# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- HMD PF03201.16 CEG35072.1 - 0.024 14.9 0.6 2.7 8.3 0.2 2.2 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase IGPD PF00475.18 CEG35072.1 - 0.093 13.0 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Benyvirus_14KDa PF07255.11 CEG35072.1 - 0.11 12.7 0.6 0.16 12.2 0.5 1.4 1 1 0 1 1 1 0 Benyvirus 14KDa protein GerD PF17898.1 CEG35072.1 - 0.33 10.9 5.0 2.6 8.0 1.5 2.2 1 1 1 2 2 2 0 Spore germination GerD central core domain FKBP_N PF01346.18 CEG35072.1 - 1.2 10.2 6.1 0.53 11.3 1.2 2.3 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pkinase PF00069.25 CEG35076.1 - 6.5e-65 219.1 0.0 1.1e-64 218.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35076.1 - 3.6e-26 92.0 0.0 6.5e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG35076.1 - 0.00023 20.6 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEG35076.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG35076.1 - 0.072 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 CEG35077.1 - 6.5e-18 65.1 0.4 1.1e-17 64.3 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CEG35077.1 - 4.3e-13 49.1 1.9 1.2e-12 47.7 1.9 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CEG35077.1 - 3.2e-06 27.0 0.6 0.038 13.8 0.0 3.2 2 1 1 3 3 3 2 Endonuclease-reverse transcriptase DNA_pol_E_B PF04042.16 CEG35078.1 - 1.7e-37 128.9 1.2 2.7e-37 128.2 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 CEG35078.1 - 3.4e-09 37.0 0.2 6.7e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Gon7 PF08738.10 CEG35078.1 - 0.18 11.9 0.2 0.37 10.9 0.2 1.4 1 0 0 1 1 1 0 Gon7 family PX PF00787.24 CEG35081.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PX domain Trypsin_2 PF13365.6 CEG35084.1 - 2e-17 64.5 0.0 4.4e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PPC PF04151.15 CEG35084.1 - 0.0043 18.1 12.8 0.033 15.3 1.2 4.0 3 0 0 3 3 3 2 Bacterial pre-peptidase C-terminal domain CUB PF00431.20 CEG35084.1 - 0.0051 17.1 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 CUB domain Peptidase_S46 PF10459.9 CEG35084.1 - 0.092 11.4 2.3 0.73 8.4 0.6 2.1 2 0 0 2 2 2 0 Peptidase S46 Y_Y_Y PF07495.13 CEG35084.1 - 0.1 12.6 0.2 1.2 9.1 0.0 2.8 4 0 0 4 4 4 0 Y_Y_Y domain MBG PF17883.1 CEG35084.1 - 0.32 11.6 5.0 1.2 9.8 1.2 3.4 2 1 1 3 3 3 0 MBG domain His_Phos_1 PF00300.22 CEG35085.1 - 4.3e-08 33.1 0.0 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Nup84_Nup100 PF04121.13 CEG35088.1 - 3.8e-148 494.8 11.7 4.9e-148 494.4 11.7 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 ubiquitin PF00240.23 CEG35088.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Metallopep PF12044.8 CEG35090.1 - 4.7e-58 196.8 0.0 1.1e-57 195.5 0.0 1.5 1 1 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 CEG35090.1 - 0.0027 17.6 0.2 0.0052 16.6 0.2 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 CEG35090.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CEG35090.1 - 0.031 14.8 0.2 0.056 14.0 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CEG35090.1 - 0.04 14.1 0.2 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CEG35090.1 - 0.041 13.1 1.0 0.083 12.1 0.8 1.6 2 0 0 2 2 2 0 Met-zincin Jacalin PF01419.17 CEG35090.1 - 0.041 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Jacalin-like lectin domain Peptidase_M54 PF07998.11 CEG35090.1 - 0.18 11.7 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 CEG35090.1 - 0.35 9.8 2.0 0.41 9.5 0.7 1.7 2 0 0 2 2 2 0 Peptidase M66 DJ-1_PfpI PF01965.24 CEG35091.1 - 1.4e-40 138.8 0.1 1.6e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3449 PF11931.8 CEG35092.1 - 8.7e-74 247.3 2.9 8.7e-74 247.3 2.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CEG35092.1 - 3.5e-27 94.7 0.1 9.4e-27 93.4 0.1 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 CEG35092.1 - 1.7e-10 40.6 0.4 6.5e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 CEG35092.1 - 1.5e-08 34.7 2.4 1.5e-08 34.7 2.4 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG35092.1 - 7.7e-07 29.3 6.2 1.7e-06 28.2 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEG35092.1 - 0.0043 17.4 1.3 0.072 13.4 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEG35092.1 - 0.091 13.7 3.5 14 6.9 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Csm1_B PF18211.1 CEG35092.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Csm1 subunit domain B DUF917 PF06032.12 CEG35092.1 - 0.18 10.6 0.4 0.28 10.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) Desulfoferrod_N PF06397.12 CEG35092.1 - 0.36 10.5 1.2 0.7 9.6 1.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-MIZ PF02891.20 CEG35093.1 - 1.8e-14 53.2 7.1 1.8e-14 53.2 7.1 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 CEG35093.1 - 5e-06 26.1 0.2 1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 SAP domain PINIT PF14324.6 CEG35093.1 - 8.9e-05 22.9 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 PINIT domain PHD_2 PF13831.6 CEG35093.1 - 0.00029 20.3 6.5 0.00029 20.3 6.5 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CEG35093.1 - 0.00074 19.4 9.2 0.00074 19.4 9.2 2.4 2 0 0 2 2 2 1 PHD-finger FANC_SAP PF18081.1 CEG35093.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain MCR PF18509.1 CEG35093.1 - 0.3 10.7 2.8 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Magnetochrome domain C1_1 PF00130.22 CEG35093.1 - 5.7 6.9 20.4 0.1 12.5 6.1 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CEG35094.1 - 3.2e-68 230.0 0.0 4.1e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35094.1 - 3e-42 144.7 0.0 4.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG35094.1 - 2e-05 24.1 0.0 7e-05 22.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 CEG35094.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CEG35094.1 - 0.17 10.6 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NitrOD1 PF18549.1 CEG35095.1 - 0.043 13.8 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 UQ_con PF00179.26 CEG35096.1 - 1e-30 106.2 0.0 3.8e-18 65.5 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme GHBP PF12772.7 CEG35097.1 - 0.058 12.9 6.6 0.015 14.8 2.1 2.2 2 0 0 2 2 2 0 Growth hormone receptor binding V_ATPase_I PF01496.19 CEG35097.1 - 0.14 10.0 1.1 0.32 8.8 1.1 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rab_bind PF16704.5 CEG35097.1 - 0.76 9.9 3.4 41 4.3 0.3 3.7 3 0 0 3 3 3 0 Rab binding domain Ras PF00071.22 CEG35098.1 - 1.3e-43 148.4 0.0 1.7e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG35098.1 - 5.8e-30 104.0 0.0 8.9e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG35098.1 - 6.6e-15 55.0 0.0 8.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG35098.1 - 3.7e-06 26.5 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CEG35098.1 - 6.3e-05 22.0 0.3 0.00024 20.1 0.1 1.9 1 1 2 3 3 3 1 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 CEG35098.1 - 0.017 14.5 0.1 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CEG35098.1 - 0.018 14.6 0.0 0.059 12.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CEG35098.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CEG35098.1 - 0.027 14.9 0.0 0.037 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CEG35098.1 - 0.056 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DENN PF02141.21 CEG35099.1 - 2.1e-31 109.3 0.4 7.2e-31 107.6 0.4 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CEG35099.1 - 0.0019 18.2 0.1 0.0053 16.7 0.1 1.8 1 0 0 1 1 1 1 dDENN domain RGS PF00615.19 CEG35099.1 - 0.0079 16.5 5.1 0.66 10.3 2.8 2.8 2 0 0 2 2 2 2 Regulator of G protein signaling domain 4HB_MCP_1 PF12729.7 CEG35099.1 - 0.22 11.0 1.1 0.43 10.1 1.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UPF0052 PF01933.18 CEG35100.1 - 5.3e-84 281.9 0.0 5.3e-84 281.9 0.0 2.4 3 0 0 3 3 3 1 Uncharacterised protein family UPF0052 DEAD PF00270.29 CEG35100.1 - 5.2e-44 150.1 0.0 1.4e-43 148.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG35100.1 - 6.9e-23 81.1 0.0 2e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEG35100.1 - 3.7e-16 59.1 0.1 9.7e-16 57.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) HAD_2 PF13419.6 CEG35100.1 - 1.4e-06 28.5 0.0 7.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase ResIII PF04851.15 CEG35100.1 - 3.4e-06 27.2 0.1 0.0001 22.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Hydrolase PF00702.26 CEG35100.1 - 0.00051 20.4 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cluap1 PF10234.9 CEG35101.1 - 0.07 12.5 14.1 0.094 12.1 8.2 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DTW PF03942.15 CEG35102.1 - 0.0086 15.8 1.3 0.011 15.5 1.3 1.2 1 0 0 1 1 1 1 DTW domain Laminin_B PF00052.18 CEG35102.1 - 0.19 11.6 3.8 0.58 10.0 0.1 2.7 1 1 2 3 3 3 0 Laminin B (Domain IV) DUF16 PF01519.16 CEG35102.1 - 0.4 11.2 8.9 0.061 13.8 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 CEG35102.1 - 0.87 9.9 10.7 1.3 9.2 10.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein UPF0242 PF06785.11 CEG35102.1 - 1.7 8.7 14.9 1.2 9.2 7.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 CEG35102.1 - 2 8.8 19.3 3.2 8.1 19.3 1.3 1 1 0 1 1 1 0 Fez1 SlyX PF04102.12 CEG35102.1 - 6.2 7.5 10.0 3.8 8.2 4.9 2.5 1 1 1 2 2 2 0 SlyX FlxA PF14282.6 CEG35102.1 - 7.7 6.6 16.2 0.22 11.5 9.1 2.0 2 0 0 2 2 2 0 FlxA-like protein EamA PF00892.20 CEG35103.1 - 1.2e-15 57.9 33.4 2.1e-08 34.4 8.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family NTP_transf_3 PF12804.7 CEG35103.1 - 1e-06 29.2 0.0 3.6e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CEG35103.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Vps39_2 PF10367.9 CEG35105.1 - 1.5e-30 105.9 0.3 3.5e-30 104.7 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CEG35105.1 - 9e-18 64.8 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CEG35105.1 - 1.9e-07 31.1 1.6 0.28 11.1 0.0 4.7 5 1 0 5 5 5 2 Region in Clathrin and VPS Vps39_1 PF10366.9 CEG35105.1 - 0.003 17.8 0.2 0.05 13.9 0.0 3.1 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 FAD_binding_7 PF03441.14 CEG35106.1 - 1.8e-76 256.1 0.5 2.8e-76 255.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEG35106.1 - 2.1e-39 135.2 0.1 5.5e-39 133.8 0.1 1.7 2 0 0 2 2 2 1 DNA photolyase ADH_zinc_N PF00107.26 CEG35106.1 - 0.069 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase T4SS-DNA_transf PF02534.14 CEG35106.1 - 0.086 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DHC_N1 PF08385.12 CEG35107.1 - 7e-167 556.5 13.6 7e-167 556.5 13.6 3.5 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG35107.1 - 5.6e-149 495.5 0.0 2.1e-148 493.7 0.0 2.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG35107.1 - 8.4e-120 400.5 21.2 8.4e-120 400.5 21.2 4.4 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG35107.1 - 2.4e-95 318.8 0.0 7.7e-95 317.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG35107.1 - 2.6e-85 286.4 0.1 1e-84 284.4 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG35107.1 - 3.9e-85 284.5 1.2 3.9e-85 284.5 1.2 2.4 3 0 0 3 3 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG35107.1 - 2.5e-72 242.2 0.2 2e-66 222.9 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG35107.1 - 4.6e-52 176.1 0.6 1.2e-51 174.8 0.1 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG35107.1 - 9.4e-48 163.0 11.1 2e-47 161.9 11.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG35107.1 - 5.9e-41 139.3 0.0 2.2e-39 134.2 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG35107.1 - 1e-23 83.8 0.3 3e-22 79.1 0.1 3.6 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CEG35107.1 - 4.4e-23 81.8 0.0 1.6e-08 34.7 0.0 5.6 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CEG35107.1 - 6.1e-16 58.5 0.0 5.5e-15 55.4 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 CEG35107.1 - 3.2e-09 37.4 0.6 0.074 13.4 0.0 5.8 6 0 0 6 6 5 2 AAA ATPase domain AAA PF00004.29 CEG35107.1 - 3.4e-09 37.2 2.4 0.099 13.1 0.0 6.4 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG35107.1 - 1e-08 35.5 0.6 0.037 14.3 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 CEG35107.1 - 0.00062 19.5 0.4 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CEG35107.1 - 0.00083 19.9 0.0 0.2 12.2 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CEG35107.1 - 0.001 19.4 1.4 2.4 8.5 0.0 4.4 4 0 0 4 4 3 1 AAA domain Tropomyosin_1 PF12718.7 CEG35107.1 - 0.0015 18.7 6.6 0.0015 18.7 6.6 3.2 3 0 0 3 3 1 1 Tropomyosin like UPF0242 PF06785.11 CEG35107.1 - 0.0029 17.8 3.3 0.0029 17.8 3.3 3.5 4 0 0 4 4 2 1 Uncharacterised protein family (UPF0242) N-terminus EAP30 PF04157.16 CEG35107.1 - 0.0034 16.7 7.7 0.032 13.5 0.1 3.4 2 0 0 2 2 2 1 EAP30/Vps36 family Sigma54_activat PF00158.26 CEG35107.1 - 0.0086 15.8 0.0 1.8 8.2 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CEG35107.1 - 0.0087 16.4 0.0 3.4 8.1 0.0 3.5 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 CEG35107.1 - 0.014 15.7 1.0 0.85 9.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CEG35107.1 - 0.014 14.5 0.1 0.24 10.4 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MscS_porin PF12795.7 CEG35107.1 - 0.022 14.3 8.6 0.14 11.6 8.6 2.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain PhoH PF02562.16 CEG35107.1 - 0.04 13.4 0.4 0.36 10.2 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 CEG35107.1 - 0.046 13.1 0.1 0.46 9.8 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Atg14 PF10186.9 CEG35107.1 - 0.046 12.8 2.7 0.14 11.2 2.7 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RsgA_GTPase PF03193.16 CEG35107.1 - 0.059 13.3 0.1 0.7 9.8 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 CEG35107.1 - 0.084 13.0 0.1 94 3.1 0.0 3.9 3 0 0 3 3 3 0 AAA domain Spidroin_N PF16763.5 CEG35107.1 - 0.1 12.7 3.2 9.3 6.3 0.1 3.0 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Minor_capsid_3 PF12691.7 CEG35107.1 - 0.12 12.8 0.4 0.74 10.2 0.4 2.4 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage ResIII PF04851.15 CEG35107.1 - 0.14 12.1 2.4 1 9.3 0.0 3.7 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit TolA_bind_tri PF16331.5 CEG35107.1 - 0.55 10.3 8.8 4.9 7.3 8.8 2.8 1 0 0 1 1 1 0 TolA binding protein trimerisation ArlS_N PF18719.1 CEG35107.1 - 1 9.6 4.3 4.5 7.5 0.0 3.4 2 0 0 2 2 2 0 ArlS sensor domain ADIP PF11559.8 CEG35107.1 - 2.1 8.4 14.9 0.48 10.5 9.1 3.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Snf7 PF03357.21 CEG35108.1 - 0.0069 16.0 0.4 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 Snf7 TK PF00265.18 CEG35110.1 - 0.032 14.1 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase Vps36_ESCRT-II PF11605.8 CEG35111.1 - 0.00039 20.5 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 CEG35111.1 - 0.003 17.4 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 CEG35111.1 - 0.029 14.7 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain UPF1_Zn_bind PF09416.10 CEG35112.1 - 1.9e-74 248.7 3.0 4.3e-74 247.6 1.2 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CEG35112.1 - 1.6e-59 200.9 0.0 2.8e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG35112.1 - 1.7e-50 172.2 3.6 1.1e-30 107.3 0.3 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CEG35112.1 - 5.8e-27 93.8 0.0 1.2e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CEG35112.1 - 2.4e-13 50.3 1.1 1.4e-12 47.8 1.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG35112.1 - 1.6e-09 38.3 0.3 3.4e-09 37.2 0.3 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CEG35112.1 - 0.00035 20.2 0.3 0.054 13.0 0.3 2.4 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 CEG35112.1 - 0.00037 19.8 2.1 0.0047 16.2 0.4 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CEG35112.1 - 0.00053 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CEG35112.1 - 0.00061 19.7 0.3 0.0017 18.2 0.3 1.8 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 CEG35112.1 - 0.016 14.7 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.14 CEG35112.1 - 0.018 14.2 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATPase PF06745.13 CEG35112.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Ribosomal_S13_N PF08069.12 CEG35112.1 - 0.026 14.5 0.0 0.086 12.9 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.29 CEG35112.1 - 0.052 14.0 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEG35112.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain HCMV_UL139 PF12507.8 CEG35112.1 - 0.11 12.9 0.3 0.23 11.9 0.3 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein AAA_16 PF13191.6 CEG35112.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CEG35112.1 - 0.16 12.0 0.0 0.64 10.0 0.0 2.1 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEG35112.1 - 0.17 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-H2C2_2 PF13465.6 CEG35114.1 - 2.4e-14 53.0 22.4 6.9e-07 29.4 0.6 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEG35114.1 - 2.6e-11 43.3 34.6 3.1e-05 24.2 1.5 5.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG35114.1 - 8.4e-09 35.5 31.5 0.0027 18.4 1.0 5.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEG35114.1 - 2e-06 28.0 7.2 0.0017 18.6 1.4 3.1 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CEG35114.1 - 0.00037 20.2 12.5 0.23 11.3 0.1 4.2 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CEG35114.1 - 0.00081 19.1 12.0 0.18 11.6 1.2 3.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CEG35114.1 - 0.0064 16.8 0.1 8.6 6.8 0.0 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CEG35114.1 - 0.02 15.3 3.6 3.2 8.3 0.2 3.4 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CEG35114.1 - 0.023 14.7 6.7 0.62 10.1 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Vanabin-2 PF11437.8 CEG35114.1 - 2.5 8.3 4.7 2.9 8.1 0.2 2.5 1 1 2 3 3 3 0 Vanadium-binding protein 2 EF-hand_7 PF13499.6 CEG35115.1 - 2.9e-09 37.3 1.8 0.00046 20.6 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG35115.1 - 2.3e-07 30.2 0.6 0.0021 17.9 0.1 3.2 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CEG35115.1 - 4e-07 29.1 0.1 0.0018 17.7 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEG35115.1 - 2.1e-06 27.5 0.0 0.00069 19.4 0.1 3.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG35115.1 - 0.00022 20.6 0.3 0.01 15.3 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CEG35115.1 - 0.13 12.6 1.2 34 4.9 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain Peptidase_M28 PF04389.17 CEG35116.1 - 8.4e-33 113.7 0.1 1.3e-32 113.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 DEAD PF00270.29 CEG35120.1 - 4.9e-46 156.7 0.2 1e-45 155.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG35120.1 - 6.7e-25 87.6 0.1 7.7e-24 84.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEG35120.1 - 6.5e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEG35120.1 - 9.6e-07 29.0 0.6 1.9e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEG35120.1 - 0.0027 17.4 0.1 0.02 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG35120.1 - 0.023 15.0 1.0 0.11 12.7 1.0 2.1 1 1 0 1 1 1 0 AAA domain DUF4461 PF14688.6 CEG35120.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) TauE PF01925.19 CEG35122.1 - 9.7e-23 81.0 15.6 1.2e-11 44.7 0.2 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF1391 PF07151.12 CEG35122.1 - 0.054 13.3 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Ank_2 PF12796.7 CEG35123.1 - 1.6e-06 28.6 0.0 0.00027 21.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG35123.1 - 0.00056 20.4 0.1 0.064 13.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG35123.1 - 0.00072 19.8 0.1 3.7 8.4 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CEG35123.1 - 0.024 14.9 0.2 18 5.8 0.0 3.9 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.30 CEG35123.1 - 0.084 13.4 0.3 23 5.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Na_Ca_ex_C PF16494.5 CEG35123.1 - 0.21 12.0 2.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain UPF0242 PF06785.11 CEG35128.1 - 5.7 7.0 28.1 1.8 8.6 11.3 3.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 CEG35129.1 - 3.3e-49 167.6 0.0 7.9e-49 166.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ribosomal_L26 PF16906.5 CEG35129.1 - 3e-35 120.6 4.5 6.8e-35 119.4 4.5 1.7 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Pkinase_Tyr PF07714.17 CEG35129.1 - 1.3e-30 106.6 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KOW PF00467.29 CEG35129.1 - 0.0011 18.9 1.2 0.0031 17.4 1.2 1.7 1 0 0 1 1 1 1 KOW motif Kinase-like PF14531.6 CEG35129.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEG35129.1 - 0.036 14.0 0.0 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family TLD PF07534.16 CEG35131.1 - 3.8e-34 117.9 0.6 6.6e-34 117.1 0.6 1.4 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 CEG35131.1 - 8.7e-13 48.4 0.0 2.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain RUN PF02759.19 CEG35131.1 - 2.1e-10 40.7 0.5 4.2e-10 39.7 0.5 1.6 1 0 0 1 1 1 1 RUN domain ELMO_CED12 PF04727.13 CEG35131.1 - 1.3e-06 28.6 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family SET PF00856.28 CEG35134.1 - 6.9e-20 72.1 3.4 1.6e-18 67.7 2.0 3.0 3 1 0 3 3 3 1 SET domain AWS PF17907.1 CEG35134.1 - 1e-07 31.8 1.8 1e-07 31.8 1.8 2.2 2 0 0 2 2 2 1 AWS domain PHD PF00628.29 CEG35134.1 - 8.2e-07 28.8 6.3 8.2e-07 28.8 6.3 3.0 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 CEG35134.1 - 0.00037 20.0 1.8 0.00037 20.0 1.8 2.7 3 0 0 3 3 3 1 PHD-finger TPR_2 PF07719.17 CEG35135.1 - 1.3e-12 46.8 3.8 0.0024 17.9 0.0 5.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG35135.1 - 4.4e-10 40.0 4.6 4.2e-07 30.5 0.1 4.0 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG35135.1 - 2.8e-08 33.2 0.0 0.067 13.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG35135.1 - 1e-07 32.1 8.8 0.0086 16.8 0.1 6.7 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG35135.1 - 1.1e-05 25.9 3.7 0.0016 18.9 0.0 4.6 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35135.1 - 1.8e-05 24.6 1.0 0.014 15.6 0.0 5.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG35135.1 - 4.9e-05 23.4 0.0 0.014 15.7 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG35135.1 - 0.00013 22.1 9.0 0.07 13.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG35135.1 - 0.00058 19.7 0.3 3.1 8.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG35135.1 - 0.0015 18.2 0.0 5.5 6.8 0.0 3.9 3 1 0 3 3 3 2 TPR repeat ANAPC3 PF12895.7 CEG35135.1 - 0.007 16.6 1.8 0.05 13.8 0.1 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CEG35135.1 - 0.078 13.3 8.7 0.37 11.1 0.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35135.1 - 0.15 12.0 1.1 6.5 6.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SYF2 PF08231.12 CEG35136.1 - 2.6e-08 34.4 5.9 2.6e-08 34.4 5.9 2.2 1 1 1 2 2 2 1 SYF2 splicing factor SET PF00856.28 CEG35136.1 - 0.85 10.0 4.8 0.62 10.4 3.5 1.5 1 1 1 2 2 2 0 SET domain DUF1764 PF08576.10 CEG35136.1 - 6.6 7.7 14.3 8 7.4 10.5 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SOR_SNZ PF01680.17 CEG35137.1 - 4.5e-109 363.0 9.9 4.5e-109 363.0 9.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 CEG35137.1 - 3.2e-08 33.2 8.8 1e-07 31.6 1.0 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 CEG35137.1 - 7.1e-05 22.0 2.6 0.12 11.4 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 CEG35137.1 - 0.00045 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 CEG35137.1 - 0.0031 17.0 1.1 0.078 12.4 0.1 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 CEG35137.1 - 0.013 14.7 2.2 0.042 13.0 0.1 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CEG35137.1 - 0.014 14.6 0.1 0.34 10.0 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase IMPDH PF00478.25 CEG35137.1 - 0.028 13.4 1.9 0.038 13.0 1.9 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CEG35137.1 - 0.034 13.5 9.1 0.042 13.2 0.8 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase Fapy_DNA_glyco PF01149.24 CEG35137.1 - 0.058 14.0 0.1 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain TauE PF01925.19 CEG35138.1 - 2.9e-28 99.1 31.2 8e-18 64.9 4.0 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF1345 PF07077.11 CEG35138.1 - 0.0088 15.8 1.2 0.0088 15.8 1.2 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1345) CwsA PF10814.8 CEG35138.1 - 0.053 13.7 0.3 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF485 PF04341.12 CEG35138.1 - 5.6 7.0 12.7 0.17 11.9 2.0 3.5 2 2 1 3 3 3 0 Protein of unknown function, DUF485 SgrT PF15894.5 CEG35139.1 - 0.031 14.2 0.4 0.083 12.9 0.4 1.7 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT tRNA-synt_His PF13393.6 CEG35139.1 - 0.3 10.3 1.4 0.67 9.2 1.4 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RIB43A PF05914.12 CEG35140.1 - 3.8e-69 233.3 63.1 4.7e-69 232.9 63.1 1.0 1 0 0 1 1 1 1 RIB43A AAA_2 PF07724.14 CEG35141.1 - 4.2e-44 150.7 0.0 9.8e-44 149.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEG35141.1 - 5.2e-15 56.0 0.2 1.5e-14 54.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CEG35141.1 - 1.4e-11 44.3 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 CEG35141.1 - 1e-05 25.8 0.6 9.5e-05 22.7 0.2 2.5 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CEG35141.1 - 2.3e-05 24.4 0.5 0.00057 19.9 0.3 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEG35141.1 - 3.3e-05 23.7 0.2 0.004 16.9 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 CEG35141.1 - 0.00029 20.0 0.1 0.0009 18.4 0.1 1.8 2 0 0 2 2 2 1 MCM P-loop domain IstB_IS21 PF01695.17 CEG35141.1 - 0.00044 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CEG35141.1 - 0.00059 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CEG35141.1 - 0.0014 18.4 0.0 0.0089 15.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 CEG35141.1 - 0.0016 18.9 0.1 0.0056 17.2 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 CEG35141.1 - 0.002 18.3 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CEG35141.1 - 0.0023 17.4 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEG35141.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG35141.1 - 0.0041 17.5 0.1 0.017 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 CEG35141.1 - 0.0042 17.2 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.16 CEG35141.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 CEG35141.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CEG35141.1 - 0.026 13.6 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 CEG35141.1 - 0.04 14.5 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG35141.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_8 PF12780.7 CEG35141.1 - 0.067 12.5 0.0 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 IPT PF01745.16 CEG35141.1 - 0.075 12.4 0.2 0.21 10.9 0.2 1.7 1 0 0 1 1 1 0 Isopentenyl transferase AAA_24 PF13479.6 CEG35141.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CEG35141.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CEG35141.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 CEG35141.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PDZ_6 PF17820.1 CEG35142.1 - 3.1e-09 36.5 0.6 0.00013 21.7 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 CEG35142.1 - 3.2e-09 37.0 0.0 5.7e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 PDZ domain Urease_gamma PF00547.18 CEG35142.1 - 0.024 15.0 0.2 0.069 13.5 0.2 1.7 1 0 0 1 1 1 0 Urease, gamma subunit vATP-synt_AC39 PF01992.16 CEG35142.1 - 0.052 13.0 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit DUF739 PF05339.11 CEG35143.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF910 PF06014.11 CEG35146.1 - 0.0024 17.8 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF910) Josephin PF02099.17 CEG35147.1 - 5.9e-10 39.5 0.0 8.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Josephin RELT PF12606.8 CEG35147.1 - 0.15 11.1 0.7 7.4 5.7 0.0 2.8 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 Choline_transpo PF04515.12 CEG35148.1 - 1e-83 281.3 27.3 5.4e-83 278.9 25.4 2.6 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF2628 PF10947.8 CEG35148.1 - 1.2 9.5 9.7 1.3 9.4 7.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) DUF1477 PF07346.11 CEG35150.1 - 0.015 15.5 2.3 1.9 8.7 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1477) Sec63 PF02889.16 CEG35152.1 - 4.5e-77 258.7 7.8 1.3e-53 181.8 0.4 2.9 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEG35152.1 - 1.6e-49 168.1 12.8 1.7e-28 99.5 2.3 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase Pkinase PF00069.25 CEG35152.1 - 7e-45 153.5 0.0 1.6e-44 152.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35152.1 - 3.7e-42 144.4 0.1 2e-41 142.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase ResIII PF04851.15 CEG35152.1 - 6.4e-23 81.6 5.5 6.4e-14 52.3 0.4 3.1 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEG35152.1 - 8.4e-11 42.3 0.9 0.0002 21.7 0.3 3.7 2 1 0 2 2 2 2 AAA domain Helicase_C PF00271.31 CEG35152.1 - 1.5e-10 41.4 4.5 9.7e-05 22.7 0.0 4.8 4 2 0 4 4 3 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 CEG35152.1 - 2.2e-05 24.9 5.5 0.059 13.7 0.6 4.5 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 CEG35152.1 - 0.00011 22.0 0.0 0.77 9.5 0.0 3.5 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA PF00004.29 CEG35152.1 - 0.0051 17.2 5.6 4.2 7.8 0.0 4.4 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Neurensin PF14927.6 CEG35152.1 - 0.011 15.4 0.0 0.04 13.6 0.0 2.0 1 0 0 1 1 1 0 Neurensin APH PF01636.23 CEG35152.1 - 0.018 15.0 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mg_chelatase PF01078.21 CEG35152.1 - 0.024 14.0 0.0 25 4.2 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TMEM100 PF16311.5 CEG35152.1 - 0.031 13.9 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 AAA_11 PF13086.6 CEG35152.1 - 0.065 13.0 19.6 0.18 11.5 0.1 5.8 3 2 1 5 5 5 0 AAA domain Helicase_PWI PF18149.1 CEG35152.1 - 0.065 13.4 3.9 0.25 11.6 3.9 2.0 1 0 0 1 1 1 0 N-terminal helicase PWI domain Sigma54_activ_2 PF14532.6 CEG35152.1 - 0.21 11.7 11.2 0.45 10.6 0.1 4.1 4 1 0 4 4 4 0 Sigma-54 interaction domain UvrD-helicase PF00580.21 CEG35152.1 - 0.38 10.2 14.8 0.1 12.1 0.1 4.4 4 1 0 4 4 4 0 UvrD/REP helicase N-terminal domain Peroxidase_2 PF01328.17 CEG35154.1 - 3.6e-14 53.7 0.0 3.9e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Rep_fac_C PF08542.11 CEG35156.1 - 5.9e-16 58.7 0.0 3.4e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CEG35156.1 - 5.9e-15 55.8 0.0 1.7e-14 54.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEG35156.1 - 4.6e-14 52.5 0.0 6.6e-11 42.3 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CEG35156.1 - 9.6e-08 32.2 0.0 6e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CEG35156.1 - 2.5e-05 24.1 0.0 6.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 CEG35156.1 - 3.9e-05 23.5 0.1 6.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 CEG35156.1 - 0.00024 21.5 0.0 0.00052 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG35156.1 - 0.00059 20.1 0.3 1.5 9.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 CEG35156.1 - 0.00062 19.6 0.1 0.0023 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CEG35156.1 - 0.00082 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 CEG35156.1 - 0.00088 19.3 0.5 0.017 15.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CEG35156.1 - 0.0012 18.3 0.1 0.032 13.7 0.0 2.4 2 1 1 3 3 2 1 Bacterial TniB protein AAA_18 PF13238.6 CEG35156.1 - 0.0014 19.2 0.1 0.036 14.6 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEG35156.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CEG35156.1 - 0.003 17.6 0.0 0.086 12.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG35156.1 - 0.0031 17.3 0.2 0.02 14.7 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CEG35156.1 - 0.0035 17.1 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEG35156.1 - 0.0043 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 CEG35156.1 - 0.0066 16.4 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CEG35156.1 - 0.0087 16.4 0.1 0.24 11.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEG35156.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 CEG35156.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CEG35156.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PE PF00934.20 CEG35156.1 - 0.032 14.5 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 PE family SNF2_N PF00176.23 CEG35156.1 - 0.038 12.7 0.0 0.11 11.2 0.0 1.8 3 0 0 3 3 3 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 CEG35156.1 - 0.043 13.2 0.1 0.21 11.0 0.1 1.9 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CEG35156.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MCM PF00493.23 CEG35156.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain PhoH PF02562.16 CEG35156.1 - 0.11 11.9 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 CEG35156.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CEG35156.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain GTP_EFTU PF00009.27 CEG35157.1 - 3.2e-44 150.8 0.0 4.1e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEG35157.1 - 8.3e-28 96.9 0.5 4.9e-27 94.5 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEG35157.1 - 1.7e-11 44.3 0.1 5.6e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG35157.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CEG35157.1 - 0.029 14.2 0.3 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu domain 4 FeoB_N PF02421.18 CEG35157.1 - 0.13 11.8 0.0 5.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Methyltransf_11 PF08241.12 CEG35158.1 - 1.3e-19 70.6 0.4 2.5e-14 53.7 0.1 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 CEG35158.1 - 5.3e-18 65.5 1.0 1.1e-12 48.4 0.1 3.4 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEG35158.1 - 6.5e-14 52.5 0.0 6.4e-09 36.5 0.0 3.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CEG35158.1 - 1e-12 48.1 0.0 2e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEG35158.1 - 1.2e-08 34.6 0.1 0.0026 17.3 0.0 3.4 2 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 CEG35158.1 - 6.5e-07 29.3 0.1 0.00094 19.1 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.17 CEG35158.1 - 3.9e-05 23.1 0.0 0.0013 18.2 0.0 2.9 2 1 1 3 3 3 2 Spermine/spermidine synthase domain Ubie_methyltran PF01209.18 CEG35158.1 - 0.0001 21.7 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 CEG35158.1 - 0.0037 17.0 0.1 0.019 14.6 0.1 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 CEG35158.1 - 0.031 13.6 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_3 PF01596.17 CEG35158.1 - 0.034 13.3 0.0 0.078 12.1 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase DUF2388 PF09498.10 CEG35158.1 - 0.051 13.6 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Methyltransf_5 PF01795.19 CEG35158.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 MraW methylase family EF-hand_7 PF13499.6 CEG35159.1 - 3.3e-22 78.7 1.1 3.5e-11 43.4 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair fn3 PF00041.21 CEG35159.1 - 8.3e-21 74.1 0.0 0.0006 20.1 0.0 5.3 5 0 0 5 5 5 4 Fibronectin type III domain EF-hand_1 PF00036.32 CEG35159.1 - 5.4e-17 60.0 11.7 4.5e-05 22.7 0.4 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CEG35159.1 - 2e-14 52.2 4.5 0.0022 17.8 0.1 5.0 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG35159.1 - 1.1e-13 50.8 3.9 0.0006 19.6 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG35159.1 - 1.5e-12 46.4 16.6 8e-05 22.0 0.2 5.1 5 0 0 5 5 5 3 EF hand Pur_ac_phosph_N PF16656.5 CEG35159.1 - 2.1e-08 34.6 0.3 0.11 13.0 0.0 4.8 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain PriCT_2 PF08707.11 CEG35159.1 - 1.7e-05 25.1 4.2 0.09 13.2 0.4 3.8 3 0 0 3 3 3 2 Primase C terminal 2 (PriCT-2) DUF2369 PF10179.9 CEG35159.1 - 0.0004 20.7 0.0 3.1 8.2 0.0 3.8 4 0 0 4 4 4 2 Uncharacterised conserved protein (DUF2369) CBP4 PF07960.11 CEG35159.1 - 0.018 14.9 0.3 0.056 13.3 0.3 1.8 1 0 0 1 1 1 0 CBP4 Npa1 PF11707.8 CEG35160.1 - 0.014 14.8 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Mtd_N PF18454.1 CEG35160.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain DUF4065 PF13274.6 CEG35161.1 - 0.01 16.7 2.3 0.01 16.7 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) Glyco_hydro_65N PF03636.15 CEG35161.1 - 0.029 14.0 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF3443 PF11925.8 CEG35161.1 - 0.079 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) RGS PF00615.19 CEG35162.1 - 1e-25 90.3 4.9 6.3e-18 65.2 0.3 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4211 PF13926.6 CEG35163.1 - 3.8e-21 75.7 0.6 3.8e-21 75.7 0.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) zf-C3HC4_3 PF13920.6 CEG35163.1 - 4.6e-11 42.4 8.2 4.6e-11 42.4 8.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Stealth_CR2 PF11380.8 CEG35164.1 - 3.2e-36 123.8 0.0 6.5e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CEG35164.1 - 1e-12 47.7 2.2 1.8e-12 46.9 2.2 1.4 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 CEG35164.1 - 3.3e-06 26.7 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 CEG35164.1 - 3.3e-05 23.7 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 CEG35165.1 - 6.6e-36 122.8 0.1 1.5e-35 121.7 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CEG35165.1 - 5.5e-11 42.2 2.4 1.2e-10 41.1 2.4 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 CEG35165.1 - 1.9e-08 33.8 0.0 4.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 CEG35165.1 - 2.6e-08 33.6 0.0 6.7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 NDUF_B12 PF08122.12 CEG35165.1 - 0.089 12.8 0.3 0.21 11.6 0.3 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Ten1_2 PF15490.6 CEG35166.1 - 0.052 13.3 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Pkinase PF00069.25 CEG35167.1 - 6.8e-57 192.8 0.0 8.2e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35167.1 - 1.4e-43 149.1 0.0 1.8e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG35167.1 - 0.00012 21.2 1.3 0.00026 20.1 1.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG35167.1 - 0.00057 18.8 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEG35167.1 - 0.0041 16.5 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG35167.1 - 0.0049 16.8 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG35167.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orn_Arg_deC_N PF02784.16 CEG35169.1 - 7.9e-33 113.8 0.0 2.1e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEG35169.1 - 3.3e-09 36.9 0.0 7.2e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CH_2 PF06294.11 CEG35170.1 - 1.4e-23 82.8 0.7 8.9e-23 80.2 0.0 2.1 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CEG35170.1 - 1.9e-12 46.9 0.0 3.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain dTDP_sugar_isom PF00908.17 CEG35170.1 - 0.1 12.2 0.4 1 9.1 0.0 2.3 2 1 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase bVLRF1 PF18826.1 CEG35171.1 - 6.7e-51 172.1 0.0 1.5e-50 170.9 0.0 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 CEG35171.1 - 4.5e-10 39.2 0.3 4.5e-10 39.2 0.3 2.4 3 0 0 3 3 3 1 Vms1-associating treble clef domain Ank_4 PF13637.6 CEG35171.1 - 4.2e-06 27.2 0.0 9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG35171.1 - 4.4e-05 23.7 0.0 9.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG35171.1 - 0.00022 21.5 0.3 0.00058 20.2 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 CEG35171.1 - 0.00026 21.2 0.0 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CEG35171.1 - 0.00028 21.4 0.0 0.00056 20.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) acVLRF1 PF18859.1 CEG35171.1 - 0.0067 16.7 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor AAA_23 PF13476.6 CEG35171.1 - 0.15 12.6 6.1 0.98 9.9 6.6 1.9 1 1 0 1 1 1 0 AAA domain NinG PF05766.12 CEG35171.1 - 0.17 11.8 9.4 1.5 8.7 5.7 2.7 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DHHC PF01529.20 CEG35172.1 - 1.3e-34 119.2 13.4 1.3e-34 119.2 13.4 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Epsilon_antitox PF08998.11 CEG35172.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial epsilon antitoxin SSTK-IP PF15836.5 CEG35173.1 - 0.12 12.5 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Arm PF00514.23 CEG35173.1 - 0.14 12.2 1.0 2.3 8.4 0.2 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GCFC PF07842.12 CEG35174.1 - 1.6e-60 205.1 6.7 2.4e-60 204.5 6.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CEG35174.1 - 6.5e-05 22.7 4.1 8.4e-05 22.4 2.6 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CEG35174.1 - 0.0009 19.3 1.9 0.0026 17.8 1.9 1.7 1 0 0 1 1 1 1 G-patch domain Lsm_interact PF05391.11 CEG35174.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Lsm interaction motif Tox-REase-7 PF15649.6 CEG35174.1 - 0.12 12.7 0.2 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 PAXIP1_C PF15364.6 CEG35174.1 - 0.17 12.2 0.4 0.36 11.1 0.4 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Retrotran_gag_2 PF14223.6 CEG35175.1 - 1.9e-18 66.5 0.1 2.6e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 CEG35175.1 - 2.7 7.9 11.2 4.7 7.1 11.2 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 CEG35176.1 - 3.2e-19 69.3 0.0 4.1e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG35176.1 - 3.5e-06 26.7 0.0 9e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 CEG35176.1 - 0.0044 16.8 0.0 0.0089 15.8 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease RVP_2 PF08284.11 CEG35179.1 - 0.00089 19.0 0.0 0.008 15.9 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEG35179.1 - 0.003 18.2 0.0 0.0071 17.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG35179.1 - 0.0086 16.6 0.0 0.024 15.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Methyltransf_25 PF13649.6 CEG35184.1 - 3.8e-08 33.9 0.0 6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG35184.1 - 4.8e-08 32.6 0.0 6.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CEG35184.1 - 5.8e-08 32.7 0.0 8.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG35184.1 - 1.4e-06 27.9 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CEG35184.1 - 4.4e-05 24.0 0.0 0.0001 22.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEG35184.1 - 5.6e-05 22.7 0.0 7.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 CEG35184.1 - 7.4e-05 22.5 0.3 0.00076 19.2 0.3 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.13 CEG35184.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 CEG35184.1 - 0.00012 21.7 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 CEG35184.1 - 0.00017 21.3 0.1 0.00023 20.8 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 CEG35184.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEG35184.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG35184.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CEG35184.1 - 0.0019 17.6 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 CEG35184.1 - 0.013 16.3 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 CEG35184.1 - 0.031 13.9 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 CEG35184.1 - 0.05 13.6 0.1 0.089 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.19 CEG35184.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_Mtase PF02384.16 CEG35184.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_8 PF05148.15 CEG35184.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 CEG35184.1 - 0.24 11.1 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 DNA methylase RTC PF01137.21 CEG35187.1 - 1.3e-54 184.7 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CEG35187.1 - 3.4e-34 117.4 0.0 5.7e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TIG PF01833.24 CEG35188.1 - 1.7e-280 906.1 253.2 6.2e-12 45.4 0.3 55.1 56 0 0 56 56 56 48 IPT/TIG domain TIG_plexin PF17960.1 CEG35188.1 - 4.1e-59 196.6 60.8 0.012 15.6 0.0 43.1 49 0 0 49 49 49 18 TIG domain Anth_Ig PF05587.13 CEG35188.1 - 3.5e-10 40.1 18.2 0.85 10.0 0.0 14.9 19 0 0 19 19 19 3 Anthrax receptor extracellular domain Ephrin_rec_like PF07699.13 CEG35188.1 - 0.00016 21.4 0.5 0.00016 21.4 0.5 7.6 8 2 1 9 9 9 3 Putative ephrin-receptor like DUF3871 PF12987.7 CEG35188.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) SH2_2 PF14633.6 CEG35189.1 - 4.9e-58 196.1 0.0 1.3e-57 194.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 CEG35189.1 - 1e-18 67.6 0.2 1e-18 67.6 0.2 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CEG35189.1 - 9.5e-11 42.1 1.0 2.7e-10 40.7 1.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CEG35189.1 - 4.2e-09 36.9 24.3 4.2e-09 36.9 24.3 4.5 3 1 0 4 4 4 2 Acidic N-terminal SPT6 Tex_N PF09371.10 CEG35189.1 - 5.4e-08 32.7 0.1 8.1e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 CEG35189.1 - 4.9e-07 30.5 1.2 3.4e-06 27.9 0.1 3.1 2 1 0 2 2 2 1 HHH domain YqgF PF14639.6 CEG35189.1 - 7.6e-07 29.0 0.0 3.6e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 CEG35189.1 - 0.0018 18.7 0.0 0.016 15.6 0.0 2.5 2 1 0 2 2 2 1 Tex protein YqgF-like domain HHH_3 PF12836.7 CEG35189.1 - 0.012 15.8 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif LZ_Tnp_IS66 PF13007.7 CEG35189.1 - 8.1 7.3 9.7 4.4 8.1 0.1 3.6 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Rhabdo_M1 PF03342.13 CEG35190.1 - 0.019 14.4 0.1 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Colicin_Ia PF11504.8 CEG35190.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Colicin Ia EGF_2 PF07974.13 CEG35191.1 - 1.7e-09 37.8 51.2 4.8e-05 23.6 5.4 5.4 5 0 0 5 5 5 5 EGF-like domain Rav1p_C PF12234.8 CEG35192.1 - 3.1e-41 141.5 6.3 2.6e-39 135.2 3.2 3.1 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40 PF00400.32 CEG35192.1 - 4.3e-08 33.7 10.9 0.21 12.5 0.2 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35193.1 - 0.002 18.4 0.0 0.65 10.3 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG35193.1 - 0.0059 17.4 0.0 0.058 14.3 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat R3H-assoc PF13902.6 CEG35193.1 - 1.7 9.0 4.2 0.86 10.0 0.1 2.1 1 1 1 2 2 2 0 R3H-associated N-terminal domain Dynamin_N PF00350.23 CEG35194.1 - 3.7e-11 43.4 0.0 1.5e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CEG35194.1 - 4.2e-07 30.0 0.0 1.4e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG35194.1 - 0.0069 16.3 0.2 1.7 8.5 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 CEG35194.1 - 0.0086 16.3 0.1 5.1 7.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CEG35194.1 - 0.023 14.2 0.2 3.1 7.3 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 CEG35194.1 - 0.07 12.4 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Cnn_1N PF07989.11 CEG35195.1 - 1e-10 41.6 7.4 1e-10 41.6 7.4 12.1 6 3 3 10 10 10 4 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CEG35195.1 - 0.0052 16.8 19.6 0.0052 16.8 19.6 9.3 1 1 8 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YnfE PF17452.2 CEG35195.1 - 0.018 15.3 1.9 0.018 15.3 1.9 5.2 4 1 1 5 5 5 0 Uncharacterized YnfE-like SNF2_N PF00176.23 CEG35197.1 - 1.8e-58 198.0 0.0 3.7e-58 196.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG35197.1 - 6.8e-19 68.3 0.0 2e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG35197.1 - 3.4e-10 40.2 0.1 2.4e-09 37.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEG35197.1 - 0.00013 21.2 2.7 0.00074 18.8 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.6 CEG35197.1 - 0.00082 18.4 0.0 0.0019 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 HA2 PF04408.23 CEG35198.1 - 1.3e-20 73.7 0.0 1.3e-20 73.7 0.0 3.6 5 1 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG35198.1 - 6.6e-12 45.6 0.0 1.8e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG35198.1 - 1.1e-11 45.0 0.0 3.6e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG35198.1 - 1.4e-07 31.4 0.2 3.3e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG35198.1 - 2.3e-05 24.7 0.1 8.2e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEG35198.1 - 0.00057 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG35198.1 - 0.0012 19.2 0.4 0.0037 17.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG35198.1 - 0.0045 17.5 0.4 0.02 15.4 0.0 2.3 2 0 0 2 2 1 1 ABC transporter Flavi_DEAD PF07652.14 CEG35198.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 CEG35198.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 CEG35198.1 - 0.013 15.5 0.2 0.075 13.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CEG35198.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 CEG35198.1 - 0.019 15.1 0.0 0.1 12.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CEG35198.1 - 0.029 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Rhodanese PF00581.20 CEG35198.1 - 0.043 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain AAA_7 PF12775.7 CEG35198.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 CEG35198.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CEG35198.1 - 0.12 12.7 0.2 0.5 10.7 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CEG35198.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.7 3 2 0 3 3 2 0 AAA domain Laminin_B PF00052.18 CEG35199.1 - 2.1e-11 43.8 0.0 8.1e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Laminin B (Domain IV) Sel1 PF08238.12 CEG35200.1 - 2.5e-25 88.4 20.6 1e-05 26.0 0.9 9.1 9 0 0 9 9 9 6 Sel1 repeat TPR_17 PF13431.6 CEG35200.1 - 0.085 13.3 14.9 9.5 6.9 1.2 6.5 4 2 2 6 6 6 0 Tetratricopeptide repeat HCMVantigenic_N PF12154.8 CEG35200.1 - 0.1 12.7 0.2 0.25 11.5 0.2 1.6 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV DUF4363 PF14276.6 CEG35200.1 - 6.8 6.9 7.5 6.6 6.9 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Cpn10 PF00166.21 CEG35202.1 - 2e-26 91.9 0.0 2.4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Amidohydro_1 PF01979.20 CEG35203.1 - 2e-65 221.4 0.0 2.5e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEG35203.1 - 7.1e-11 42.2 0.6 2.6e-05 23.9 0.0 2.2 2 1 0 2 2 2 2 Amidohydrolase family Herpes_UL49_1 PF03117.14 CEG35203.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 UL49 family PA14 PF07691.12 CEG35204.1 - 0.075 12.8 0.0 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 PA14 domain Amidase02_C PF12123.8 CEG35204.1 - 0.14 11.9 0.4 6.6 6.5 0.1 2.4 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase SLC3A2_N PF16028.5 CEG35205.1 - 0.0074 15.8 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Xpo1 PF08389.12 CEG35207.1 - 1.8e-09 37.8 4.2 2.1e-06 27.9 0.1 3.7 3 1 1 4 4 4 2 Exportin 1-like protein SAPS PF04499.15 CEG35209.1 - 0.016 14.0 10.7 0.02 13.7 10.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 CEG35209.1 - 2.4 7.5 13.4 4.1 6.7 13.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 CEG35209.1 - 3.6 7.6 5.5 6.5 6.7 5.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.6 CEG35209.1 - 9.1 4.9 15.1 12 4.5 15.1 1.2 1 0 0 1 1 1 0 Raftlin COX1 PF00115.20 CEG35215.1 - 1.5e-11 43.9 0.3 1.5e-11 43.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I EF-hand_8 PF13833.6 CEG35216.1 - 5e-05 23.1 0.1 7.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Acyltransferase PF01553.21 CEG35217.1 - 4.7e-21 74.8 0.0 9.3e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CEG35217.1 - 9.7e-10 38.4 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF4363 PF14276.6 CEG35217.1 - 0.029 14.5 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Pkinase PF00069.25 CEG35219.1 - 4.9e-46 157.2 0.0 6.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35219.1 - 1.3e-25 90.2 0.0 1.5e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG35219.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG35219.1 - 0.064 12.2 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CEG35219.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CEG35219.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase zf-U1 PF06220.12 CEG35220.1 - 6.2e-08 32.3 5.8 6.2e-08 32.3 5.8 1.7 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2 PF00096.26 CEG35220.1 - 0.064 13.7 1.7 0.18 12.3 1.7 1.8 1 1 0 1 1 1 0 Zinc finger, C2H2 type PyrI_C PF02748.15 CEG35220.1 - 0.16 11.9 1.0 0.25 11.3 0.4 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.6 CEG35220.1 - 0.56 10.7 0.4 0.56 10.7 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEG35220.1 - 0.82 10.7 3.5 0.44 11.5 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger EAP30 PF04157.16 CEG35221.1 - 2e-66 223.7 0.7 2.2e-66 223.5 0.7 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF836 PF05768.14 CEG35221.1 - 0.12 12.8 0.0 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Arf PF00025.21 CEG35222.1 - 3.8e-61 205.6 0.0 4.3e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CEG35222.1 - 1.2e-09 37.8 0.0 3.1e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CEG35222.1 - 8.9e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG35222.1 - 1.1e-07 31.6 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEG35222.1 - 4.1e-07 30.1 0.0 5.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEG35222.1 - 3.2e-06 26.7 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEG35222.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEG35222.1 - 0.0032 17.0 0.0 0.14 11.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CEG35222.1 - 0.031 13.9 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Antibiotic_NAT PF02522.14 CEG35222.1 - 0.059 13.2 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase PduV-EutP PF10662.9 CEG35222.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF5319 PF17252.2 CEG35222.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Torus PF16131.5 CEG35223.1 - 2.9e-32 111.6 1.0 5.1e-32 110.8 0.3 1.8 2 0 0 2 2 2 1 Torus domain WW PF00397.26 CEG35223.1 - 3.3e-10 39.9 1.4 8.8e-10 38.5 1.4 1.8 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 CEG35223.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 CEG35223.1 - 1.5e-06 27.4 3.4 3.4e-06 26.3 3.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf_CCCH_4 PF18345.1 CEG35223.1 - 0.0017 18.3 2.1 0.0046 17.0 2.1 1.8 1 0 0 1 1 1 1 Zinc finger domain DZR PF12773.7 CEG35223.1 - 0.022 14.8 1.3 0.046 13.8 1.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEG35223.1 - 0.036 13.8 2.6 0.074 12.8 2.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CEG35223.1 - 0.068 13.1 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-CCCH_4 PF18044.1 CEG35223.1 - 1.3 8.9 5.6 3 7.8 5.6 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger Pkinase PF00069.25 CEG35231.1 - 1.2e-65 221.5 0.2 2.3e-65 220.6 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 CEG35231.1 - 1.1e-48 166.1 3.8 1.7e-44 152.4 0.2 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C Pkinase_Tyr PF07714.17 CEG35231.1 - 8.9e-38 130.0 0.2 1.7e-37 129.2 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CEG35231.1 - 3.2e-37 126.5 0.0 1.7e-17 63.2 0.1 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CEG35231.1 - 2.5e-06 27.0 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG35231.1 - 3.4e-05 23.9 0.2 0.41 10.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Nif11 PF07862.11 CEG35231.1 - 0.099 13.0 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Nif11 domain Phage_pRha PF09669.10 CEG35231.1 - 0.099 13.2 3.4 25 5.5 0.2 3.9 4 0 0 4 4 4 0 Phage regulatory protein Rha (Phage_pRha) WD40 PF00400.32 CEG35232.1 - 8.1e-07 29.7 5.6 0.002 18.9 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat TFIIIC_delta PF12657.7 CEG35232.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.6 CEG35232.1 - 0.041 13.9 0.1 0.81 9.8 0.0 2.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 CEG35232.1 - 0.25 11.3 1.6 1 9.4 0.1 2.8 4 0 0 4 4 4 0 PQQ enzyme repeat GAS PF13851.6 CEG35233.1 - 8.7e-64 214.6 28.0 8.7e-64 214.6 28.0 3.3 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CEG35233.1 - 2.4 7.5 61.2 0.032 13.7 16.0 3.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 Pilus_CpaD PF09476.10 CEG35233.1 - 7.4 6.2 10.0 0.96 9.1 0.1 3.7 2 1 3 5 5 5 0 Pilus biogenesis CpaD protein (pilus_cpaD) Presenilin PF01080.17 CEG35234.1 - 4e-86 289.3 7.7 6e-86 288.7 7.7 1.2 1 0 0 1 1 1 1 Presenilin NOT2_3_5 PF04153.18 CEG35235.1 - 7.2e-24 84.4 1.0 2.7e-23 82.5 1.0 1.9 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family APG6_N PF17675.1 CEG35238.1 - 1.6 9.3 18.6 6.8 7.2 9.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Lipase_3 PF01764.25 CEG35241.1 - 2.1e-06 27.6 0.2 1.2e-05 25.2 0.1 2.3 2 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEG35241.1 - 0.0044 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CEG35241.1 - 0.01 15.6 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEG35241.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 CEG35241.1 - 0.025 13.7 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 CEG35241.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold ANAPC4_WD40 PF12894.7 CEG35243.1 - 4e-10 39.9 2.6 0.0041 17.4 0.0 5.7 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 CEG35245.1 - 9.7e-07 28.7 0.4 9.7e-07 28.7 0.4 2.3 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 Presenilin PF01080.17 CEG35245.1 - 0.086 11.6 0.5 0.14 10.9 0.5 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CEG35245.1 - 0.14 10.9 4.0 0.27 10.0 4.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec16 PF12932.7 CEG35245.1 - 2.3 8.8 5.2 2.9 8.5 0.1 3.1 2 1 1 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region DUF4834 PF16118.5 CEG35245.1 - 3.4 8.7 7.6 10 7.1 7.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CTU2 PF10288.9 CEG35245.1 - 4 7.7 9.8 23 5.3 0.1 2.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 UPF0560 PF10577.9 CEG35245.1 - 4.1 5.8 11.0 6.7 5.1 11.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 CEG35245.1 - 7.4 5.4 10.6 12 4.7 10.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 CEG35245.1 - 9.7 5.9 6.2 19 4.9 4.8 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S8 PF00082.22 CEG35246.1 - 6.8e-46 156.9 1.7 1.2e-45 156.1 1.7 1.4 1 0 0 1 1 1 1 Subtilase family zf-Di19 PF05605.12 CEG35246.1 - 4.5e-06 26.8 9.4 0.0033 17.7 0.3 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CEG35246.1 - 0.00011 21.9 3.3 0.14 12.0 1.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Zap1_zf2 PF18217.1 CEG35246.1 - 0.00055 19.9 0.1 1.3 9.1 0.1 2.6 2 0 0 2 2 2 2 Zap1 zinc finger 2 zf-C2H2_4 PF13894.6 CEG35246.1 - 0.0047 17.7 8.2 0.55 11.2 3.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2719 PF10891.8 CEG35246.1 - 0.019 14.8 2.6 2.3 8.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2719) zf-C2H2 PF00096.26 CEG35246.1 - 0.61 10.6 5.7 21 5.8 2.9 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type RT_RNaseH_2 PF17919.1 CEG35247.1 - 5.3e-24 84.2 0.0 1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEG35247.1 - 7.2e-21 74.5 0.0 1.5e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SSF PF00474.17 CEG35249.1 - 4.9e-84 282.5 15.7 4.9e-84 282.5 15.7 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family Peptidase_C1 PF00112.23 CEG35252.1 - 2.5e-50 171.6 8.3 3.6e-50 171.1 8.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CEG35252.1 - 0.084 11.6 0.4 3.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase C1-like family DUF455 PF04305.14 CEG35254.1 - 1.2e-80 270.7 1.8 1.3e-80 270.5 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) PWWP PF00855.17 CEG35255.1 - 2e-08 34.5 0.1 1.3e-07 31.9 0.1 2.4 1 0 0 1 1 1 1 PWWP domain EVE PF01878.18 CEG35255.1 - 0.24 11.4 2.4 0.71 9.9 2.4 1.8 1 0 0 1 1 1 0 EVE domain CRAL_TRIO PF00650.20 CEG35257.1 - 1.1e-15 57.7 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG35257.1 - 0.049 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GOLD_2 PF13897.6 CEG35257.1 - 5.3 7.5 0.0 5.3 7.5 0.0 2.8 2 1 1 3 3 3 0 Golgi-dynamics membrane-trafficking NPV_P10 PF05531.12 CEG35258.1 - 0.52 10.8 4.3 1.1 9.7 1.3 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DHO_dh PF01180.21 CEG35261.1 - 1.8e-102 342.5 0.0 2.2e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CEG35261.1 - 0.058 12.4 0.5 0.13 11.2 0.5 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase UCH PF00443.29 CEG35263.1 - 1.6e-33 116.3 0.4 4.5e-33 114.8 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CMS1 PF14617.6 CEG35263.1 - 1.1e-24 87.2 2.3 2.2e-24 86.2 2.3 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UCH_1 PF13423.6 CEG35263.1 - 3.5e-17 63.0 2.4 2.5e-16 60.2 2.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG35263.1 - 4e-13 48.9 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 CEG35263.1 - 6.4e-06 26.7 5.8 0.21 12.2 0.0 4.0 3 1 0 3 3 3 2 DUSP domain DEAD PF00270.29 CEG35263.1 - 7.4e-05 22.6 0.1 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Peroxin-22 PF12827.7 CEG35263.1 - 0.022 14.7 0.2 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family DUF3800 PF12686.7 CEG35263.1 - 0.17 12.5 1.6 6 7.5 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Ran_BP1 PF00638.18 CEG35267.1 - 7.5e-09 35.9 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Cupin_8 PF13621.6 CEG35267.1 - 0.038 13.7 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Cupin-like domain MFS_1 PF07690.16 CEG35270.1 - 0.0026 16.7 6.4 0.0033 16.4 6.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 CEG35270.1 - 0.02 13.9 2.8 0.024 13.6 2.8 1.1 1 0 0 1 1 1 0 PUCC protein Phageshock_PspG PF09583.10 CEG35270.1 - 0.17 12.2 2.9 0.25 11.6 0.8 2.0 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) DUF2009 PF09418.10 CEG35274.1 - 4.2e-176 586.5 0.2 4.3e-127 425.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2009) Mod_r PF07200.13 CEG35275.1 - 0.0084 16.2 0.5 0.01 15.9 0.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RraB PF06877.11 CEG35275.1 - 0.16 12.7 0.3 0.32 11.8 0.3 1.4 1 0 0 1 1 1 0 Regulator of ribonuclease activity B ABC_tran PF00005.27 CEG35276.1 - 1.5e-50 171.3 0.0 6.4e-29 101.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CEG35276.1 - 2.2e-49 168.6 39.2 7.5e-28 97.9 11.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CEG35276.1 - 6.7e-12 45.3 6.3 6.5e-06 25.7 0.2 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG35276.1 - 2.1e-06 27.3 0.7 0.014 15.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEG35276.1 - 7.5e-06 26.0 0.0 0.06 13.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CEG35276.1 - 1.6e-05 25.5 0.2 0.034 14.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CEG35276.1 - 4.4e-05 23.5 0.4 0.48 10.2 0.0 4.4 5 1 1 6 6 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEG35276.1 - 0.00012 22.5 0.2 0.07 13.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEG35276.1 - 0.00017 21.5 0.3 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 CEG35276.1 - 0.00069 19.8 1.5 0.024 14.7 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 CEG35276.1 - 0.0012 19.0 0.1 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 CEG35276.1 - 0.0021 17.7 0.9 0.038 13.6 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CEG35276.1 - 0.0038 16.7 0.2 0.67 9.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CEG35276.1 - 0.007 16.1 1.0 0.75 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 CEG35276.1 - 0.0076 15.4 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEG35276.1 - 0.0078 16.5 1.8 1.3 9.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CEG35276.1 - 0.01 15.6 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 CEG35276.1 - 0.015 15.0 0.1 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEG35276.1 - 0.021 14.2 0.5 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 CEG35276.1 - 0.028 14.8 0.2 18 5.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.12 CEG35276.1 - 0.052 12.8 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CEG35276.1 - 0.053 13.7 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 CEG35276.1 - 0.056 12.2 0.0 0.37 9.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_33 PF13671.6 CEG35276.1 - 0.06 13.5 0.1 2 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG35276.1 - 0.062 13.7 0.2 0.92 9.9 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.12 CEG35276.1 - 0.062 12.6 0.1 0.89 8.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CEG35276.1 - 0.065 13.0 1.5 1.9 8.2 0.0 3.1 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 CEG35276.1 - 0.085 13.1 0.1 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CEG35276.1 - 0.088 12.0 0.6 8.9 5.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CEG35276.1 - 0.11 11.4 0.7 3.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CEG35276.1 - 0.11 11.5 0.3 10 5.1 0.1 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_PrkA PF08298.11 CEG35276.1 - 0.13 11.2 0.1 0.34 9.8 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain AAA_35 PF14516.6 CEG35276.1 - 0.15 10.9 0.1 0.68 8.7 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ABC_ATPase PF09818.9 CEG35276.1 - 2.2 7.0 4.4 10 4.8 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 CEG35276.1 - 4.5 7.1 5.7 21 5.0 0.0 3.2 3 0 0 3 3 3 0 NTPase DUF5102 PF17104.5 CEG35279.1 - 7 6.6 16.4 3.1 7.8 9.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5102) Anoctamin PF04547.12 CEG35280.1 - 1.8e-119 399.6 8.2 2.4e-119 399.2 8.2 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 CEG35280.1 - 0.0089 15.4 1.0 0.019 14.3 1.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF2207 PF09972.9 CEG35280.1 - 0.03 13.1 3.2 2.3 6.9 0.2 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) COX15-CtaA PF02628.15 CEG35280.1 - 0.16 11.0 1.4 2.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein FeoB_associated PF12669.7 CEG35280.1 - 0.38 11.2 2.7 10 6.6 0.7 2.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF1218 PF06749.12 CEG35280.1 - 1.1 9.8 3.4 3.4 8.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF805 PF05656.14 CEG35280.1 - 4.3 7.8 8.4 0.7 10.3 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF805) NOG1_N PF17835.1 CEG35281.1 - 1.9e-56 190.5 1.4 1.9e-56 190.5 1.4 2.9 3 0 0 3 3 3 2 NOG1 N-terminal helical domain NOG1 PF06858.14 CEG35281.1 - 1.9e-27 94.8 0.9 3.6e-27 93.9 0.2 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CEG35281.1 - 6.4e-24 83.7 1.3 1.6e-23 82.4 1.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CEG35281.1 - 1.2e-17 64.1 0.0 3.8e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG35281.1 - 1.4e-10 41.0 0.1 2.3e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 CEG35281.1 - 0.00026 20.6 0.1 0.00062 19.4 0.1 1.7 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 CEG35281.1 - 0.0046 16.3 0.2 0.013 14.9 0.2 1.8 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CEG35281.1 - 0.034 14.5 0.1 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CEG35281.1 - 0.065 13.3 5.3 5.9 6.9 0.0 3.7 3 1 1 4 4 4 0 Dynamin family G-alpha PF00503.20 CEG35281.1 - 0.094 11.9 2.8 0.36 10.0 0.2 2.4 2 0 0 2 2 2 0 G-protein alpha subunit TipE PF16972.5 CEG35281.1 - 0.23 10.6 1.6 0.39 9.9 1.6 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE MeaB PF03308.16 CEG35281.1 - 0.31 10.0 0.0 0.31 10.0 0.0 2.5 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Golgin_A5 PF09787.9 CEG35282.1 - 0.0063 16.0 22.7 0.0063 16.0 22.7 8.5 2 2 6 8 8 8 3 Golgin subfamily A member 5 GPS2_interact PF15784.5 CEG35282.1 - 0.0073 16.7 3.3 0.0073 16.7 3.3 10.1 7 5 5 12 12 12 1 G-protein pathway suppressor 2-interacting domain TMF_DNA_bd PF12329.8 CEG35282.1 - 0.0096 15.9 0.6 0.0096 15.9 0.6 16.3 9 4 5 15 15 15 4 TATA element modulatory factor 1 DNA binding DUF3800 PF12686.7 CEG35282.1 - 0.019 15.6 0.1 20 5.8 0.1 5.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Shugoshin_N PF07558.11 CEG35282.1 - 0.084 12.8 0.1 0.084 12.8 0.1 7.9 9 1 0 9 9 9 0 Shugoshin N-terminal coiled-coil region DUF4042 PF13251.6 CEG35283.1 - 4.1e-16 59.2 13.5 1.8e-14 53.9 3.0 5.9 6 2 1 7 7 7 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 CEG35283.1 - 1.8e-15 57.1 2.6 0.0013 19.1 0.1 7.1 8 0 0 8 8 8 3 HEAT repeats HEAT PF02985.22 CEG35283.1 - 1e-14 53.4 20.9 0.16 12.3 0.2 11.4 11 0 0 11 11 11 4 HEAT repeat RTP1_C1 PF10363.9 CEG35283.1 - 7.9e-06 26.0 0.0 0.2 11.9 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 CEG35283.1 - 9.4e-06 24.9 7.1 0.023 13.8 0.1 4.0 5 0 0 5 5 5 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 CEG35283.1 - 0.00042 20.9 0.6 22 5.7 0.0 6.0 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEG35283.1 - 0.0009 19.7 15.3 0.37 11.3 0.5 8.2 9 1 1 10 10 8 1 HEAT-like repeat HEAT_PBS PF03130.16 CEG35283.1 - 0.01 16.5 0.5 0.49 11.2 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Tti2 PF10521.9 CEG35283.1 - 0.012 15.2 0.0 0.15 11.5 0.0 2.7 3 0 0 3 3 3 0 Tti2 family Cnd3 PF12719.7 CEG35283.1 - 0.017 14.4 0.0 0.13 11.4 0.0 2.5 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.7 CEG35283.1 - 0.031 14.2 1.1 0.56 10.1 0.0 3.6 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TAF6_C PF07571.13 CEG35283.1 - 0.05 13.9 1.6 17 5.8 0.0 4.8 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 CEG35283.1 - 0.48 10.5 9.1 1.6 8.8 1.2 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SAP PF02037.27 CEG35284.1 - 3.2e-10 39.5 3.9 3.2e-10 39.5 3.9 2.4 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 CEG35284.1 - 1.7e-09 37.9 1.2 1.7e-09 37.9 1.2 3.2 2 2 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 CEG35284.1 - 0.022 14.6 0.0 0.065 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NusG_II PF07009.11 CEG35284.1 - 0.16 12.2 3.2 0.33 11.2 3.2 1.5 1 0 0 1 1 1 0 NusG domain II Vasculin PF15337.6 CEG35284.1 - 1.1 10.1 0.1 1.1 10.1 0.1 3.1 2 1 1 3 3 3 0 Vascular protein family Vasculin-like 1 HrpB1_HrpK PF09613.10 CEG35285.1 - 0.56 9.8 2.8 1.8 8.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) API5 PF05918.11 CEG35290.1 - 1.2e-07 31.0 0.2 3.1e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) RRM_1 PF00076.22 CEG35290.1 - 3.4e-05 23.6 0.0 0.0057 16.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5578 PF17741.1 CEG35290.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5578) CENP-T_C PF15511.6 CEG35292.1 - 2.6e-08 33.9 0.1 3.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEG35292.1 - 0.00029 21.2 0.1 0.00042 20.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CEG35292.1 - 0.00042 20.4 0.1 0.00064 19.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CEG35292.1 - 0.0062 16.9 0.2 0.0094 16.3 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEG35292.1 - 0.0062 16.8 0.1 0.011 16.0 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEG35292.1 - 0.038 14.1 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEG35292.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 CEG35293.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CEG35293.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CEG35293.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEG35293.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEG35293.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEG35293.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pex2_Pex12 PF04757.14 CEG35294.1 - 1.2e-20 74.1 0.7 1.6e-20 73.6 0.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 CEG35294.1 - 0.00084 19.3 11.8 0.00084 19.3 11.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG35294.1 - 0.0085 16.4 10.3 0.022 15.1 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CEG35294.1 - 0.011 15.6 8.0 0.022 14.6 8.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG35294.1 - 0.037 13.9 12.4 0.085 12.7 12.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG35294.1 - 0.51 10.2 11.0 1.3 9.0 11.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mononeg_mRNAcap PF14318.6 CEG35295.1 - 0.076 12.3 0.1 0.076 12.3 0.1 1.0 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Ank_2 PF12796.7 CEG35298.1 - 1.5e-45 153.7 12.3 1.1e-10 41.9 0.4 6.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG35298.1 - 6.7e-32 109.5 16.2 3e-08 34.0 0.0 7.5 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG35298.1 - 9.9e-29 96.2 13.5 0.048 14.2 0.1 11.4 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 CEG35298.1 - 7.5e-28 96.2 15.0 4.6e-07 30.0 0.0 8.0 2 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CEG35298.1 - 2.8e-27 93.9 20.3 0.0005 20.4 0.1 11.3 10 1 1 11 11 11 7 Ankyrin repeat F-box PF00646.33 CEG35298.1 - 0.079 12.9 0.5 0.21 11.5 0.5 1.8 1 0 0 1 1 1 0 F-box domain Cnd2 PF05786.14 CEG35299.1 - 8.4e-96 322.4 39.8 2.5e-95 320.8 39.8 1.8 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CEG35299.1 - 0.00011 22.3 0.5 0.00011 22.3 0.5 3.4 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Protamine_P2 PF00841.19 CEG35299.1 - 5.3 7.6 19.6 1.2 9.6 9.9 2.8 2 0 0 2 2 2 0 Sperm histone P2 Solute_trans_a PF03619.16 CEG35300.1 - 2.4e-89 299.4 19.8 2.9e-89 299.1 19.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HisKA_4TM PF16926.5 CEG35300.1 - 0.14 11.7 0.2 0.33 10.5 0.2 1.6 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Coa1 PF08695.10 CEG35301.1 - 9.1e-05 22.2 1.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 PDT PF00800.18 CEG35302.1 - 6.4e-20 71.7 1.6 6.4e-20 71.7 1.6 2.6 3 0 0 3 3 3 1 Prephenate dehydratase SRP_SPB PF02978.19 CEG35302.1 - 4.1e-11 43.4 3.0 3.1e-10 40.6 0.1 2.7 2 0 0 2 2 2 1 Signal peptide binding domain RRM_1 PF00076.22 CEG35303.1 - 1.9e-83 274.3 0.2 1.5e-21 76.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEG35303.1 - 9.3e-30 102.6 1.8 4.7e-29 100.4 0.8 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CEG35303.1 - 3.9e-07 29.7 0.0 0.19 11.3 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG35303.1 - 2.1e-05 24.4 0.1 0.13 12.3 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEG35303.1 - 2.7e-05 24.2 0.0 4.5 7.5 0.0 4.1 3 0 0 3 3 3 2 RNA recognition motif SET_assoc PF11767.8 CEG35303.1 - 0.0045 16.6 0.1 8.4 6.1 0.0 3.5 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 CEG35303.1 - 0.019 15.0 0.4 0.27 11.3 0.0 3.1 4 0 0 4 4 4 0 RNA binding domain OB_RNB PF08206.11 CEG35303.1 - 0.026 14.2 1.0 9.8 5.9 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain RGP PF03214.13 CEG35303.1 - 0.032 13.4 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide RCC1 PF00415.18 CEG35304.1 - 1.2e-73 243.5 26.0 3.2e-14 53.3 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG35304.1 - 6.2e-26 89.6 57.2 4.2e-07 29.6 2.2 8.5 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat GTP-bdg_M PF16360.5 CEG35305.1 - 0.15 12.7 3.4 0.37 11.4 3.4 1.7 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region MGC-24 PF05283.11 CEG35305.1 - 0.45 10.9 7.3 0.26 11.8 0.4 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2630 PF10944.8 CEG35305.1 - 7 7.2 9.0 0.94 10.0 4.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DUF4407 PF14362.6 CEG35306.1 - 3 7.1 6.3 3.6 6.9 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAP PF08373.10 CEG35307.1 - 7.8e-07 29.1 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 RAP domain GH131_N PF18271.1 CEG35309.1 - 3.5e-08 33.4 0.0 3.9e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG35309.1 - 0.024 14.5 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase SQHop_cyclase_C PF13243.6 CEG35309.1 - 0.028 13.5 0.1 0.028 13.5 0.1 1.0 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Mitoc_L55 PF09776.9 CEG35310.1 - 0.037 13.8 0.4 0.037 13.8 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 IZUMO PF15005.6 CEG35310.1 - 1.7 9.2 6.0 1.2 9.7 3.9 1.8 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SNARE PF05739.19 CEG35311.1 - 0.008 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 CEG35311.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 FAS_I_H PF18314.1 CEG35311.1 - 0.029 14.0 1.0 0.038 13.6 1.0 1.1 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Phage_Gp23 PF10669.9 CEG35311.1 - 0.8 10.0 3.1 11 6.4 0.5 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) PP2C PF00481.21 CEG35312.1 - 1.6e-74 250.8 0.0 2.1e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG35312.1 - 1.4e-06 28.1 0.0 4.1e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C GDP_Man_Dehyd PF16363.5 CEG35313.1 - 1.9e-52 178.7 0.0 8.5e-52 176.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEG35313.1 - 2.1e-45 155.1 0.0 2.6e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CEG35313.1 - 9.7e-08 31.5 0.2 0.00028 20.2 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CEG35313.1 - 1.3e-07 31.0 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEG35313.1 - 2.9e-06 26.6 0.0 0.1 11.7 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEG35313.1 - 1.1e-05 24.7 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CEG35313.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG35313.1 - 0.0039 17.1 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 CEG35313.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thioredoxin PF00085.20 CEG35314.1 - 1.3e-21 76.5 0.0 1.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG35314.1 - 1.1e-05 25.8 0.0 0.00015 22.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CEG35314.1 - 2e-05 24.3 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CEG35314.1 - 0.00012 22.3 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 CEG35314.1 - 0.00028 21.0 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 CEG35314.1 - 0.00093 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CEG35314.1 - 0.0017 18.2 0.0 0.0022 17.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 CEG35314.1 - 0.0059 16.3 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEG35314.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF1281_C PF18406.1 CEG35314.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Thioredoxin_7 PF13899.6 CEG35314.1 - 0.069 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF4850 PF16142.5 CEG35314.1 - 0.17 11.3 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) AA_permease_2 PF13520.6 CEG35315.1 - 6.1e-34 117.6 32.5 5e-25 88.2 16.4 2.2 1 1 1 2 2 2 2 Amino acid permease PX PF00787.24 CEG35316.1 - 1.7e-12 47.3 0.1 3.7e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 PX domain RCC1 PF00415.18 CEG35320.1 - 4.4e-135 440.2 42.1 5.1e-15 55.8 0.6 14.7 14 0 0 14 14 14 14 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG35320.1 - 3.1e-69 227.6 61.9 5.6e-08 32.4 0.1 15.4 15 0 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 CEG35320.1 - 1.3e-28 99.5 1.4 1.1e-20 74.0 0.1 3.8 3 0 0 3 3 3 2 SPRY domain Kelch_4 PF13418.6 CEG35320.1 - 6.5e-19 67.7 19.7 0.0011 18.9 0.4 8.3 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG35320.1 - 7.3e-18 63.9 13.5 1.4e-05 24.6 0.1 5.4 5 0 0 5 5 4 3 Kelch motif Kelch_6 PF13964.6 CEG35320.1 - 2.7e-15 56.0 18.2 0.00016 21.8 0.1 8.4 8 1 1 9 9 8 4 Kelch motif Kelch_5 PF13854.6 CEG35320.1 - 3.1e-13 49.4 15.8 0.0084 16.1 0.0 8.0 8 0 0 8 8 8 4 Kelch motif FHA PF00498.26 CEG35320.1 - 2.4e-12 47.0 0.7 7e-12 45.5 0.7 1.9 1 0 0 1 1 1 1 FHA domain Kelch_3 PF13415.6 CEG35320.1 - 1.5e-11 44.3 9.6 0.19 12.0 0.0 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Yop-YscD_cpl PF16697.5 CEG35320.1 - 1.5e-07 31.6 0.0 4.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Vps62 PF06101.11 CEG35320.1 - 7.3e-07 27.9 0.0 1.8e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 HOIP-UBA PF16678.5 CEG35320.1 - 0.00021 21.3 1.4 0.00072 19.6 1.4 1.9 1 0 0 1 1 1 1 HOIP UBA domain pair Kelch_2 PF07646.15 CEG35320.1 - 0.00073 19.4 23.9 0.17 11.9 0.1 8.3 9 0 0 9 9 9 3 Kelch motif PX PF00787.24 CEG35321.1 - 2.8e-09 36.9 0.2 5.8e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 PX domain Caf4 PF11615.8 CEG35321.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 Mito_carr PF00153.27 CEG35322.1 - 1.4e-49 165.9 1.7 1.1e-15 57.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydant_A_N PF05378.13 CEG35322.1 - 0.058 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF1180 PF06679.12 CEG35323.1 - 0.0033 17.9 0.1 0.0062 17.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) MFS_2 PF13347.6 CEG35323.1 - 0.073 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein Nodulin_late PF07127.11 CEG35323.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.4 3 1 1 4 4 4 0 Late nodulin protein SAP30_Sin3_bdg PF13867.6 CEG35325.1 - 1.7e-14 53.9 0.2 3e-14 53.1 0.2 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 CEG35325.1 - 7.1e-06 25.8 5.7 1.3e-05 25.0 5.7 1.4 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.32 CEG35326.1 - 4.1e-22 78.1 2.8 0.0062 17.4 0.0 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35326.1 - 1.1e-06 28.8 0.0 1.6 9.1 0.0 5.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CEG35326.1 - 2.9e-05 23.6 0.6 0.00014 21.5 0.2 2.3 2 0 0 2 2 2 1 LisH-like dimerisation domain Carn_acyltransf PF00755.20 CEG35329.1 - 6.6e-176 586.4 0.0 7.6e-176 586.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase LemA PF04011.12 CEG35329.1 - 0.09 12.6 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 LemA family Pkinase PF00069.25 CEG35330.1 - 1.5e-62 211.4 0.1 1.4e-60 204.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35330.1 - 3.6e-29 101.8 0.0 6.5e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG35330.1 - 0.00013 21.4 0.5 0.00029 20.3 0.5 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG35330.1 - 0.04 13.2 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CEG35330.1 - 0.041 12.6 0.0 0.041 12.6 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CEG35330.1 - 0.07 12.1 0.0 0.67 8.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 CEG35330.1 - 0.15 10.9 0.2 0.22 10.4 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Maf1 PF09174.10 CEG35331.1 - 4.5e-54 183.2 0.1 6e-54 182.8 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator PWI PF01480.17 CEG35331.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 PWI domain VPS9 PF02204.18 CEG35332.1 - 1.9e-28 98.7 0.0 5.1e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CEG35332.1 - 0.00037 20.7 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CAP PF00188.26 CEG35333.1 - 8.3e-10 39.6 0.1 1.4e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BRCT PF00533.26 CEG35334.1 - 9.4e-18 64.4 0.0 0.00037 20.8 0.0 3.5 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEG35334.1 - 1e-17 64.3 0.0 3.1e-11 43.5 0.0 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CEG35334.1 - 6.5e-07 29.2 3.3 0.002 18.1 0.2 4.4 4 2 0 4 4 4 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 CEG35334.1 - 8.2e-06 25.6 0.0 0.0014 18.5 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 CEG35334.1 - 3.1e-05 24.0 3.2 0.4 10.8 0.1 3.9 3 2 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PDE4_UCR PF18100.1 CEG35334.1 - 0.13 12.9 1.1 0.54 10.9 1.1 2.0 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) zf-RanBP PF00641.18 CEG35334.1 - 0.14 11.5 5.6 0.35 10.2 5.6 1.8 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SWIRM-assoc_2 PF16496.5 CEG35334.1 - 0.23 10.3 0.0 0.23 10.3 0.0 2.6 3 0 0 3 3 3 0 SWIRM-associated domain at the N-terminal GBP PF02263.19 CEG35335.1 - 7.4e-52 176.2 3.2 1.8e-38 132.3 0.0 2.2 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain Anoctamin PF04547.12 CEG35336.1 - 2.7e-67 227.6 14.0 5.6e-47 160.6 12.3 2.1 2 0 0 2 2 2 2 Calcium-activated chloride channel Mem_trans PF03547.18 CEG35336.1 - 0.2 10.0 6.3 2.1 6.7 0.2 2.4 2 0 0 2 2 2 0 Membrane transport protein DUF1635 PF07795.11 CEG35336.1 - 2.4 8.0 6.8 0.95 9.3 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Peptidase_M13_N PF05649.13 CEG35337.1 - 1.2e-75 255.6 0.7 1.6e-75 255.2 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEG35337.1 - 2.1e-67 226.7 1.2 3.9e-67 225.8 1.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 DHHC PF01529.20 CEG35338.1 - 9.5e-30 103.4 11.0 9.5e-30 103.4 11.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CEG35338.1 - 7.6e-23 80.9 1.9 6.9e-12 45.8 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG35338.1 - 4.8e-22 78.0 2.1 1.2e-06 28.9 0.2 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG35338.1 - 8.8e-20 68.7 1.1 1.9e-05 24.7 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEG35338.1 - 2e-18 66.2 3.9 1.2e-06 28.6 0.0 5.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG35338.1 - 1.1e-10 41.5 6.9 1.4e-05 25.3 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Syntaphilin PF15290.6 CEG35338.1 - 7.5 6.1 6.0 12 5.5 6.0 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp ETF PF01012.21 CEG35339.1 - 2.6e-46 157.8 1.8 3.8e-46 157.2 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Abhydrolase_1 PF00561.20 CEG35340.1 - 7.4e-34 117.5 0.2 8.9e-34 117.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG35340.1 - 8e-05 23.3 0.1 0.0001 23.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CEG35340.1 - 0.021 15.0 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF3177 PF11375.8 CEG35341.1 - 0.019 14.8 0.3 0.55 10.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3177) SCP2 PF02036.17 CEG35342.1 - 0.031 14.8 0.0 0.087 13.3 0.0 1.9 1 0 0 1 1 1 0 SCP-2 sterol transfer family WD40 PF00400.32 CEG35343.1 - 2.8e-20 72.3 7.8 0.014 16.2 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35343.1 - 4.6e-12 46.1 0.0 0.11 12.8 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEG35343.1 - 1e-07 32.2 0.1 0.32 11.5 0.0 4.4 4 0 0 4 4 4 2 PQQ-like domain Ge1_WD40 PF16529.5 CEG35343.1 - 4.1e-05 22.7 3.5 0.57 9.1 0.0 4.9 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEG35343.1 - 0.00089 18.7 0.5 0.11 11.8 0.0 2.7 1 1 1 3 3 3 2 WD40-like domain PHTB1_N PF14727.6 CEG35343.1 - 0.0014 18.1 0.1 10 5.4 0.0 3.4 3 1 0 3 3 3 2 PTHB1 N-terminus Utp8 PF10395.9 CEG35343.1 - 0.12 10.9 0.0 0.43 9.0 0.0 1.8 2 0 0 2 2 2 0 Utp8 family PQQ PF01011.21 CEG35343.1 - 0.17 11.9 0.3 47 4.2 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat DUF3272 PF11676.8 CEG35344.1 - 0.11 12.7 1.8 0.2 11.9 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3272) PDZ PF00595.24 CEG35345.1 - 6.5e-08 32.8 0.0 7.4e-06 26.2 0.0 2.9 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CEG35345.1 - 7.9e-08 32.0 0.0 0.019 14.8 0.0 3.5 3 0 0 3 3 3 2 PDZ domain Fer2_3 PF13085.6 CEG35346.1 - 6.3e-31 106.6 0.0 1.1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CEG35346.1 - 2.7e-10 40.6 4.9 2.7e-10 40.6 4.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CEG35346.1 - 4.8e-08 33.0 3.6 4.8e-08 33.0 3.6 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CEG35346.1 - 1.3e-07 32.0 7.8 1.3e-07 32.0 7.8 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 CEG35346.1 - 0.0038 17.1 0.4 0.0038 17.1 0.4 2.2 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CEG35346.1 - 0.014 15.5 6.7 0.014 15.5 6.7 2.7 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEG35346.1 - 0.017 15.7 7.8 0.017 15.7 7.8 2.7 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 CEG35346.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain IBR PF01485.21 CEG35349.1 - 6.9e-08 32.6 5.6 6.9e-08 32.6 5.6 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CEG35349.1 - 1.2e-05 25.2 4.6 1.2e-05 25.2 4.6 3.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEG35349.1 - 2.8e-05 24.4 2.7 2.8e-05 24.4 2.7 4.8 4 2 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 CEG35349.1 - 0.00018 21.4 5.2 0.00018 21.4 5.2 5.1 4 1 1 5 5 5 1 zinc-RING finger domain zf-UDP PF14569.6 CEG35349.1 - 0.013 15.5 1.9 0.013 15.5 1.9 3.1 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CEG35349.1 - 0.014 15.6 6.2 0.014 15.6 6.2 4.8 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING Yip1 PF04893.17 CEG35349.1 - 0.59 9.8 9.1 1 9.1 9.1 1.3 1 0 0 1 1 1 0 Yip1 domain zf-NADH-PPase PF09297.11 CEG35349.1 - 0.95 9.2 9.9 0.87 9.3 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF4199 PF13858.6 CEG35349.1 - 3.6 8.0 6.3 0.95 9.8 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) PRA1 PF03208.19 CEG35349.1 - 4.5 6.9 14.0 9.1 5.9 14.0 1.4 1 0 0 1 1 1 0 PRA1 family protein Methyltransf_25 PF13649.6 CEG35350.1 - 1e-05 26.1 0.0 3.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG35350.1 - 0.0017 18.9 0.0 0.0059 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain RVT_2 PF07727.14 CEG35351.1 - 2.1e-26 93.1 0.3 2.5e-26 92.8 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG35351.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3523 PF12037.8 CEG35353.1 - 8.7e-97 323.6 28.9 1.3e-96 323.1 28.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 CEG35353.1 - 1.1e-22 80.9 0.0 3.2e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG35353.1 - 7e-06 26.5 7.7 0.00013 22.4 0.4 4.4 3 1 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 CEG35353.1 - 0.00014 21.7 0.0 0.0006 19.6 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CEG35353.1 - 0.0007 19.8 1.8 0.0016 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEG35353.1 - 0.001 19.1 1.0 0.013 15.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEG35353.1 - 0.0042 16.5 0.2 0.013 14.9 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG35353.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG35353.1 - 0.0071 16.6 10.0 0.016 15.5 0.0 3.8 3 2 1 4 4 3 1 AAA domain AAA_lid_3 PF17862.1 CEG35353.1 - 0.0094 15.7 0.2 0.052 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain TsaE PF02367.17 CEG35353.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CEG35353.1 - 0.021 15.4 2.6 0.025 15.1 0.0 2.7 2 2 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CEG35353.1 - 0.031 14.0 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CEG35353.1 - 0.04 14.3 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 CEG35353.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 CEG35353.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain NPL4 PF05021.15 CEG35354.1 - 1e-22 80.9 0.1 8.2e-19 68.1 0.1 3.1 1 1 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 CEG35354.1 - 3.7e-10 40.2 0.0 7.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 CEG35354.1 - 0.026 14.3 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family HAP2-GCS1 PF10699.9 CEG35354.1 - 0.05 13.6 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Male gamete fusion factor PRK PF00485.18 CEG35355.1 - 4.8e-40 137.4 0.1 8e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CEG35355.1 - 4.6e-07 30.4 0.0 8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG35355.1 - 5.9e-05 23.2 0.0 0.00021 21.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CEG35355.1 - 0.0003 21.2 1.8 0.0083 16.6 1.1 2.7 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CEG35355.1 - 0.0011 18.7 2.7 0.21 11.3 0.0 2.5 2 1 0 3 3 3 2 Cytidylate kinase ABC_tran PF00005.27 CEG35355.1 - 0.0022 18.5 0.0 0.005 17.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter MobB PF03205.14 CEG35355.1 - 0.0031 17.4 0.1 0.0088 15.9 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.20 CEG35355.1 - 0.0032 17.2 1.0 0.21 11.3 0.1 2.4 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_26 PF13500.6 CEG35355.1 - 0.0064 16.3 0.1 0.019 14.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEG35355.1 - 0.012 14.8 0.2 0.024 13.8 0.2 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CEG35355.1 - 0.027 14.9 0.0 0.073 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 CEG35355.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CEG35355.1 - 0.036 14.3 0.0 0.42 10.9 0.0 2.4 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CEG35355.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG35355.1 - 0.05 14.0 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CEG35355.1 - 0.059 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CEG35355.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG35355.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CEG35355.1 - 0.16 12.3 0.0 0.5 10.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase EF-hand_7 PF13499.6 CEG35356.1 - 7.5e-19 68.0 1.1 2.4e-10 40.7 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG35356.1 - 1.8e-18 64.7 0.2 0.00022 20.5 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CEG35356.1 - 2.7e-17 61.1 0.3 0.00029 20.5 0.0 5.5 5 0 0 5 5 5 4 EF-hand domain VPS13_C PF16909.5 CEG35356.1 - 5e-16 59.0 4.4 1.7e-07 31.2 0.0 3.9 3 1 1 4 4 4 3 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CEG35356.1 - 5.4e-14 52.2 0.0 1.2e-12 47.8 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_5 PF13202.6 CEG35356.1 - 1.4e-08 33.8 5.2 0.031 13.8 0.0 4.6 4 0 0 4 4 4 3 EF hand ATG_C PF09333.11 CEG35356.1 - 1.2e-05 25.5 0.0 4.8e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain EF-hand_8 PF13833.6 CEG35356.1 - 1.6e-05 24.7 1.8 0.07 13.0 0.0 4.7 5 0 0 5 5 5 1 EF-hand domain pair C2 PF00168.30 CEG35356.1 - 0.0011 19.2 0.0 0.0033 17.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_4 PF12763.7 CEG35356.1 - 0.025 14.5 0.9 17 5.4 0.0 3.6 2 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG35356.1 - 0.14 12.5 0.0 0.56 10.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain DUF1380 PF07128.12 CEG35356.1 - 0.18 12.0 2.2 0.21 11.7 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) LRR_4 PF12799.7 CEG35357.1 - 2.5e-10 40.5 22.1 3.3e-05 24.2 2.5 4.1 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG35357.1 - 8.7e-08 31.9 5.8 5.8e-06 25.9 4.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CEG35357.1 - 5.3e-06 26.1 20.5 0.00016 21.4 7.0 3.9 1 1 2 4 4 4 4 Leucine rich repeat Glyco_trans_1_4 PF13692.6 CEG35360.1 - 0.00016 22.1 0.0 0.00038 20.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CEG35360.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SNF2_N PF00176.23 CEG35361.1 - 6e-08 31.8 0.8 0.0014 17.4 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain Myb_DNA-bind_6 PF13921.6 CEG35361.1 - 1.4e-07 31.6 0.0 5.3e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 CEG35361.1 - 3.4e-07 30.5 1.2 3.4e-07 30.5 1.2 3.0 3 1 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 CEG35361.1 - 4.2e-07 30.1 0.0 1.6e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ion_trans PF00520.31 CEG35362.1 - 4.4e-35 121.1 16.6 6.8e-35 120.5 16.6 1.2 1 0 0 1 1 1 1 Ion transport protein PseudoU_synth_1 PF01416.20 CEG35362.1 - 1.1e-15 58.0 0.0 6.7e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ion_trans_2 PF07885.16 CEG35362.1 - 2e-12 46.9 3.6 2e-12 46.9 3.6 2.5 3 0 0 3 3 3 1 Ion channel DUF2344 PF10105.9 CEG35362.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) EF-hand_1 PF00036.32 CEG35362.1 - 0.0083 15.6 2.6 0.02 14.4 2.6 1.7 1 0 0 1 1 1 1 EF hand Peptidase_M16_C PF05193.21 CEG35363.1 - 4.6e-32 111.5 0.0 2e-31 109.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEG35363.1 - 3.4e-28 98.5 0.0 7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Glyco_hydro_17 PF00332.18 CEG35366.1 - 4e-05 23.4 0.7 0.0002 21.1 0.2 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_2_C PF02836.17 CEG35366.1 - 0.047 12.8 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 CEG35366.1 - 0.071 12.5 0.1 0.39 10.1 0.1 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Mt_ATP-synt_D PF05873.12 CEG35366.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) MgtE_N PF03448.17 CEG35370.1 - 0.43 11.2 3.7 2.2 9.0 0.1 3.1 3 0 0 3 3 3 0 MgtE intracellular N domain IBN_N PF03810.19 CEG35371.1 - 1.6e-09 37.6 0.0 5.7e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CEG35371.1 - 8.9e-08 32.3 2.9 3.3e-06 27.2 0.9 4.2 4 1 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 CEG35371.1 - 6.3e-05 22.0 0.4 0.0015 17.5 0.4 2.7 1 1 0 1 1 1 1 Cse1 RIX1 PF08167.12 CEG35371.1 - 0.00011 22.1 0.3 0.38 10.5 0.0 4.0 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 CEG35371.1 - 0.00067 20.0 0.2 3.5 8.1 0.4 4.0 3 0 0 3 3 3 2 HEAT repeats AsnC_trans_reg PF01037.21 CEG35371.1 - 0.0086 16.0 0.0 0.67 10.0 0.0 2.9 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain ParcG PF10274.9 CEG35371.1 - 0.11 12.6 0.0 36 4.4 0.0 3.4 3 0 0 3 3 3 0 Parkin co-regulated protein HEAT PF02985.22 CEG35371.1 - 1.9 9.0 4.0 1.8e+02 2.8 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat ATP11 PF06644.11 CEG35372.1 - 2.7e-25 89.7 0.4 3.4e-25 89.4 0.4 1.0 1 0 0 1 1 1 1 ATP11 protein KMP11 PF03037.16 CEG35372.1 - 0.022 15.5 0.5 1.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 HD_3 PF13023.6 CEG35372.1 - 0.061 13.3 0.1 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 HD domain E2F_TDP PF02319.20 CEG35373.1 - 1.7e-40 136.9 1.3 3e-21 75.3 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 CEG35373.1 - 0.0028 17.5 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 CEG35373.1 - 0.0058 16.8 0.3 5.2 7.3 0.0 2.5 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC HATPase_c PF02518.26 CEG35374.1 - 2e-13 50.8 0.0 2.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEG35374.1 - 4.3e-11 42.8 0.3 6e-11 42.3 0.3 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MA3 PF02847.17 CEG35375.1 - 1.1e-24 86.6 1.5 2.4e-24 85.5 1.5 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CEG35375.1 - 1.3e-16 60.9 0.1 7.2e-16 58.5 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain DHC_N1 PF08385.12 CEG35376.1 - 7.2e-171 569.6 13.9 7.2e-171 569.6 13.9 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG35376.1 - 7e-134 445.9 4.7 2.1e-72 243.9 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG35376.1 - 3.8e-94 316.0 7.0 3.8e-94 316.0 7.0 5.7 6 2 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG35376.1 - 9.5e-77 257.8 0.2 2.5e-71 240.0 0.0 4.2 3 1 1 4 4 4 2 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG35376.1 - 1.5e-75 254.3 0.0 1.5e-75 254.3 0.0 2.9 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG35376.1 - 2.2e-75 252.5 2.8 6.4e-74 247.8 1.1 3.0 2 1 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CEG35376.1 - 2.6e-74 250.3 14.1 4.6e-74 249.5 14.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 CEG35376.1 - 4.7e-65 218.5 0.8 2.2e-58 196.8 0.1 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG35376.1 - 1.5e-38 132.2 0.0 3.7e-38 130.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG35376.1 - 1.9e-37 128.0 1.2 3.6e-32 110.9 0.4 4.2 2 1 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CEG35376.1 - 1e-23 83.9 0.0 2.1e-09 37.5 0.0 5.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CEG35376.1 - 1.5e-22 79.7 0.7 7.1e-22 77.5 0.7 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CEG35376.1 - 1.8e-13 50.7 0.0 6.4e-13 48.9 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RsgA_GTPase PF03193.16 CEG35376.1 - 1.4e-08 34.8 0.1 0.01 15.8 0.0 3.4 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 CEG35376.1 - 3.9e-08 33.6 0.1 0.024 14.9 0.0 4.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CEG35376.1 - 4.7e-08 33.6 2.7 0.1 13.0 0.0 5.7 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 CEG35376.1 - 7.3e-08 33.0 0.0 0.045 14.3 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 CEG35376.1 - 1.1e-07 32.4 0.0 0.81 10.1 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEG35376.1 - 2.1e-06 27.9 0.1 0.029 14.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 CEG35376.1 - 2.7e-06 27.9 0.0 0.082 13.4 0.0 3.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CEG35376.1 - 7.2e-06 25.7 0.4 1.2 9.0 0.1 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 CEG35376.1 - 7e-05 23.2 0.1 2.4 8.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.13 CEG35376.1 - 0.00032 20.0 2.1 0.085 12.0 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CEG35376.1 - 0.00039 20.5 0.1 0.47 10.5 0.0 4.4 5 0 0 5 5 3 1 AAA domain Mg_chelatase PF01078.21 CEG35376.1 - 0.00042 19.8 0.2 0.25 10.7 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CEG35376.1 - 0.00055 19.7 1.8 1.6 8.4 0.0 3.8 4 0 0 4 4 3 1 AAA domain TniB PF05621.11 CEG35376.1 - 0.00079 18.9 0.1 0.23 10.8 0.0 3.5 3 0 0 3 3 3 1 Bacterial TniB protein Roc PF08477.13 CEG35376.1 - 0.00091 19.4 0.5 0.3 11.3 0.1 3.6 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CEG35376.1 - 0.0031 17.8 0.6 7 7.0 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CEG35376.1 - 0.0033 17.7 0.3 5.4 7.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain Cytochrom_C PF00034.21 CEG35376.1 - 0.005 17.9 0.0 0.028 15.6 0.0 2.2 2 0 0 2 2 1 1 Cytochrome c NACHT PF05729.12 CEG35376.1 - 0.0073 16.2 1.0 2 8.3 0.0 3.3 3 0 0 3 3 2 1 NACHT domain PhoH PF02562.16 CEG35376.1 - 0.0078 15.7 1.2 6.2 6.2 0.0 3.5 3 0 0 3 3 3 0 PhoH-like protein Rad17 PF03215.15 CEG35376.1 - 0.0084 16.1 0.0 0.4 10.6 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain TsaE PF02367.17 CEG35376.1 - 0.01 15.8 1.4 56 3.7 0.1 4.5 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CEG35376.1 - 0.011 14.8 2.7 3.8 6.5 0.0 4.1 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_25 PF13481.6 CEG35376.1 - 0.035 13.7 0.6 17 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 CEG35376.1 - 0.06 13.0 0.0 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Guanylate kinase Cytidylate_kin PF02224.18 CEG35376.1 - 0.062 13.0 0.1 10 5.7 0.0 3.3 2 0 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 CEG35376.1 - 0.069 13.2 0.0 17 5.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CEG35376.1 - 0.15 11.8 0.8 13 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Yuri_gagarin PF15934.5 CEG35376.1 - 0.33 10.8 10.5 0.6 9.9 2.4 2.9 2 0 0 2 2 2 0 Yuri gagarin Sod_Cu PF00080.20 CEG35377.1 - 7.5e-33 113.7 2.0 9.2e-33 113.4 2.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4298 PF14131.6 CEG35378.1 - 0.14 12.1 3.0 0.32 11.0 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Exonuc_VII_L PF02601.15 CEG35378.1 - 0.7 9.4 7.2 1.1 8.8 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit E_raikovi_mat PF06360.11 CEG35379.1 - 0.068 13.6 5.0 0.38 11.2 0.1 3.3 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone ESCRT-II PF05871.12 CEG35381.1 - 1.9e-19 70.3 0.0 2.3e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RXLR PF16810.5 CEG35382.1 - 0.077 13.4 0.1 0.28 11.6 0.0 1.9 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Myb_DNA-binding PF00249.31 CEG35383.1 - 4.8e-10 39.5 0.0 8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG35383.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tli4_N PF18443.1 CEG35383.1 - 0.16 12.3 1.3 0.29 11.5 0.4 1.9 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain DUF2547 PF10818.8 CEG35383.1 - 1.3 10.0 7.9 0.81 10.7 0.3 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2547) RNase_H PF00075.24 CEG35384.1 - 0.0015 18.7 10.2 0.0051 17.0 1.3 3.7 2 0 0 2 2 2 2 RNase H PACT_coil_coil PF10495.9 CEG35384.1 - 0.027 15.1 0.0 0.027 15.1 0.0 6.2 6 0 0 6 6 6 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Turandot PF07240.11 CEG35384.1 - 2.4 8.2 5.4 21 5.2 0.1 3.6 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot Pkinase PF00069.25 CEG35386.1 - 6.8e-47 160.1 0.0 4.7e-31 108.1 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35386.1 - 4.9e-30 104.7 0.1 1.4e-14 54.0 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase PQQ PF01011.21 CEG35386.1 - 6.6e-07 29.0 1.2 2.5e-06 27.1 0.1 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 CEG35386.1 - 0.0027 18.1 0.7 2.6 8.6 0.1 4.2 4 0 0 4 4 4 1 PQQ-like domain Kdo PF06293.14 CEG35386.1 - 0.0066 15.8 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 CEG35386.1 - 0.01 15.5 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain YycH PF07435.11 CEG35387.1 - 0.011 14.8 0.2 0.014 14.4 0.2 1.1 1 0 0 1 1 1 0 YycH protein Pho88 PF10032.9 CEG35388.1 - 6.3e-31 107.0 0.3 1.2e-30 106.1 0.3 1.4 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 CEG35388.1 - 2e-14 53.9 0.0 3.8e-08 33.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG35388.1 - 6.8e-08 32.9 0.0 0.00012 22.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG35388.1 - 2.7e-06 27.3 0.0 0.13 12.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEG35388.1 - 1.1e-05 25.6 0.0 0.56 10.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEG35388.1 - 0.0011 19.2 0.0 0.11 12.9 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) IMPDH PF00478.25 CEG35388.1 - 0.085 11.8 0.7 0.28 10.1 0.0 1.7 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain YfcL PF08891.11 CEG35389.1 - 0.58 10.5 3.3 0.3 11.5 0.4 2.0 2 0 0 2 2 2 0 YfcL protein Dak2 PF02734.17 CEG35389.1 - 0.68 9.8 5.2 0.3 11.0 0.9 2.1 1 1 1 2 2 2 0 DAK2 domain LMBR1 PF04791.16 CEG35389.1 - 1.1 8.0 8.9 1.4 7.7 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DBINO PF13892.6 CEG35389.1 - 4.6 7.6 17.1 2.3 8.6 2.2 3.2 2 1 1 3 3 3 0 DNA-binding domain CENP-F_leu_zip PF10473.9 CEG35390.1 - 0.003 17.6 15.9 0.003 17.6 15.9 3.9 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 CEG35390.1 - 0.011 16.1 10.2 0.011 16.1 10.2 3.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) rve_3 PF13683.6 CEG35390.1 - 0.16 11.8 1.8 19 5.1 0.2 3.0 2 0 0 2 2 2 0 Integrase core domain Cytokin-bind PF09265.10 CEG35390.1 - 0.16 11.3 6.4 3 7.1 0.5 2.4 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fib_alpha PF08702.10 CEG35390.1 - 0.38 11.0 26.6 0.058 13.6 4.1 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family SPOUT_MTase_2 PF14419.6 CEG35390.1 - 0.86 8.9 4.6 0.3 10.4 0.5 2.1 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Fez1 PF06818.15 CEG35390.1 - 3.5 8.0 48.0 4.3 7.7 11.5 3.4 1 1 3 4 4 4 0 Fez1 HMMR_N PF15905.5 CEG35390.1 - 7.3 6.0 50.1 0.013 15.0 18.9 3.6 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF2315 PF10231.9 CEG35391.1 - 0.36 10.9 2.6 0.45 10.6 0.9 2.0 2 0 0 2 2 2 0 Apoptogenic protein 1 zf-C2H2 PF00096.26 CEG35392.1 - 0.013 15.9 0.5 0.042 14.3 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNAPc19 PF15497.6 CEG35392.1 - 0.68 10.4 4.8 1.7 9.2 0.2 3.3 3 0 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 ASH PF15780.5 CEG35393.1 - 4.1e-21 75.0 11.1 0.0097 16.1 0.0 9.8 9 1 0 9 9 9 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEG35393.1 - 2.3e-10 40.6 2.3 0.0027 17.8 0.0 5.9 6 0 0 6 6 6 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CEG35393.1 - 8.1e-07 28.9 0.0 0.53 10.2 0.0 5.1 5 0 0 5 5 5 3 MSP (Major sperm protein) domain PI3K_p85B PF02192.16 CEG35394.1 - 0.063 13.0 0.3 0.089 12.5 0.3 1.3 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain 4HBT PF03061.22 CEG35395.1 - 3.7e-19 68.9 1.3 2.9e-14 53.2 0.2 2.2 2 0 0 2 2 2 2 Thioesterase superfamily DBD_Tnp_Mut PF03108.15 CEG35397.1 - 2.2e-08 34.0 0.1 3.7e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase SpdB PF05122.13 CEG35397.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Mobile element transfer protein Ribosomal_L50 PF10501.9 CEG35397.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal subunit 39S Retrotran_gag_2 PF14223.6 CEG35399.1 - 1.2e-25 89.8 0.2 1.5e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 CEG35399.1 - 0.00029 21.1 0.5 0.00057 20.1 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein ATP-gua_Ptrans PF00217.19 CEG35403.1 - 2e-41 141.8 0.0 8.7e-28 97.2 0.0 2.8 2 1 1 3 3 3 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CEG35403.1 - 3e-22 78.8 0.0 5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain eIF3_N PF09440.10 CEG35404.1 - 2.8e-39 134.6 0.7 1.6e-38 132.2 1.3 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CEG35404.1 - 1e-13 51.7 0.1 2.6e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 PCI domain Glyco_tranf_2_3 PF13641.6 CEG35404.1 - 0.00043 20.2 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TPR_3 PF07720.12 CEG35404.1 - 1.6 8.8 4.1 3.4 7.8 4.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaJ PF00226.31 CEG35405.1 - 1e-19 70.4 2.0 1.4e-19 70.0 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain TMPIT PF07851.13 CEG35405.1 - 2.7 7.2 8.3 3.6 6.7 8.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein adh_short PF00106.25 CEG35406.1 - 1.2e-11 44.4 0.1 1.5e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG35406.1 - 0.0017 18.0 0.1 0.002 17.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase cNMP_binding PF00027.29 CEG35408.1 - 3.4e-37 126.4 0.8 1e-15 57.6 0.0 3.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain HECT PF00632.25 CEG35410.1 - 1.5e-29 103.5 0.1 1.1e-28 100.7 0.1 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RVT_1 PF00078.27 CEG35411.1 - 0.00031 20.3 0.0 0.003 17.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4064 PF13273.6 CEG35416.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) FKBP26_C PF18046.1 CEG35416.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 FKBP26_C-terminal Methyltr_RsmB-F PF01189.17 CEG35417.1 - 3.2e-17 62.8 0.6 1.1e-15 57.9 0.6 2.6 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SepSecS PF05889.13 CEG35418.1 - 5.5e-51 173.5 3.7 2.4e-31 108.8 0.1 3.0 2 1 1 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CLU PF13236.6 CEG35419.1 - 3.8e-78 262.3 0.0 7.5e-78 261.4 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CEG35419.1 - 4.7e-35 121.2 0.0 4.7e-35 121.2 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CEG35419.1 - 7.2e-19 67.9 0.0 1.7e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CEG35419.1 - 5e-14 52.3 13.1 1.2e-06 28.7 0.5 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35419.1 - 0.0045 16.8 14.2 0.022 14.6 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG35419.1 - 1.2 9.1 3.7 13 5.8 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 CEG35422.1 - 2.2e-42 144.6 0.0 4.1e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CEG35422.1 - 1.3e-23 82.9 0.1 3.5e-23 81.5 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 CEG35422.1 - 8.1e-12 45.0 0.0 3.4e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CEG35422.1 - 3.1e-08 33.3 0.0 1e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CEG35422.1 - 1.3e-05 25.0 0.0 3.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEG35422.1 - 3.1e-05 24.4 0.1 0.0013 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEG35422.1 - 9.3e-05 22.4 0.0 0.0008 19.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CEG35422.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CEG35422.1 - 0.00013 22.2 0.1 0.0051 17.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEG35422.1 - 0.00077 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CEG35422.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CEG35422.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CEG35422.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEG35422.1 - 0.0027 17.8 0.0 0.009 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEG35422.1 - 0.0034 17.9 0.0 0.0081 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEG35422.1 - 0.0048 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CEG35422.1 - 0.0049 16.6 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG35422.1 - 0.009 15.6 0.1 0.25 10.9 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEG35422.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Use1 PF09753.9 CEG35422.1 - 0.016 14.9 1.0 0.063 13.0 1.0 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 ATPase PF06745.13 CEG35422.1 - 0.017 14.4 0.1 6.4 6.1 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_17 PF13207.6 CEG35422.1 - 0.022 15.2 0.0 0.075 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CEG35422.1 - 0.025 13.7 0.1 0.078 12.1 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 CEG35422.1 - 0.041 13.2 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEG35422.1 - 0.063 13.2 0.0 0.37 10.7 0.0 2.0 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 CEG35422.1 - 0.078 12.9 0.1 5.6 6.8 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 CEG35422.1 - 0.085 13.0 2.0 0.096 12.9 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Zot PF05707.12 CEG35422.1 - 0.09 12.4 0.1 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) CPT PF07931.12 CEG35422.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 CEG35422.1 - 0.1 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AFG1_ATPase PF03969.16 CEG35422.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase TPR_1 PF00515.28 CEG35422.1 - 0.88 9.5 3.5 0.27 11.1 0.3 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat HSP33 PF01430.19 CEG35423.1 - 1.6e-35 122.8 0.0 1.8e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein DUF3342 PF11822.8 CEG35424.1 - 1.6e-27 95.5 0.4 3.3e-27 94.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.31 CEG35424.1 - 3.5e-05 24.0 0.5 7.6e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain CHORD PF04968.12 CEG35424.1 - 0.0011 19.7 2.5 0.0038 17.9 2.5 2.1 1 0 0 1 1 1 1 CHORD Arm PF00514.23 CEG35425.1 - 7.7e-89 289.4 12.3 2e-12 46.7 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG35425.1 - 3.5e-23 81.7 1.4 9e-06 26.1 0.0 5.8 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 CEG35425.1 - 5.4e-20 71.6 0.5 7.5e-06 26.3 0.0 5.3 3 1 2 5 5 5 5 HEAT repeats IBB PF01749.20 CEG35425.1 - 3e-18 66.0 1.9 6.5e-18 65.0 1.9 1.6 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CEG35425.1 - 4.3e-18 64.6 1.1 2.2e-17 62.4 0.7 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 CEG35425.1 - 7.4e-16 56.9 2.0 0.00022 21.2 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat V-ATPase_H_C PF11698.8 CEG35425.1 - 1.7e-06 28.2 0.1 0.046 13.8 0.0 4.0 3 1 2 5 5 5 2 V-ATPase subunit H Arm_2 PF04826.13 CEG35425.1 - 3.9e-05 23.2 0.0 0.051 13.0 0.0 2.8 1 1 1 2 2 2 2 Armadillo-like HEAT_PBS PF03130.16 CEG35425.1 - 0.0017 18.8 0.7 1.7 9.6 0.1 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CEG35425.1 - 0.013 15.5 0.5 19 5.4 0.0 3.9 4 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 CEG35425.1 - 0.015 15.5 5.3 14 6.0 0.2 4.9 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 DCB PF16213.5 CEG35425.1 - 0.096 12.3 0.2 0.34 10.6 0.0 2.0 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Mo25 PF08569.11 CEG35425.1 - 0.11 11.9 0.0 2.4 7.5 0.0 2.3 1 1 0 2 2 2 0 Mo25-like IFRD PF05004.13 CEG35425.1 - 0.35 9.9 2.7 6.7 5.7 0.1 2.8 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) EF-hand_6 PF13405.6 CEG35427.1 - 6.7e-13 47.4 0.0 2.6e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CEG35427.1 - 3.5e-10 40.2 0.0 0.00024 21.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG35427.1 - 1.5e-09 36.7 0.0 0.00025 20.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CEG35427.1 - 2.9e-08 32.8 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG35427.1 - 0.00048 19.9 0.1 1.3 9.0 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CEG35427.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain UvrD-helicase PF00580.21 CEG35427.1 - 0.068 12.7 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Caleosin PF05042.13 CEG35427.1 - 0.071 13.0 0.0 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein EF-hand_14 PF17959.1 CEG35427.1 - 0.075 13.4 0.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain PH PF00169.29 CEG35430.1 - 0.11 13.0 1.8 0.32 11.5 0.1 2.4 2 1 0 2 2 2 0 PH domain Peptidase_S28 PF05577.12 CEG35432.1 - 2.1e-82 277.3 0.0 2.5e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CEG35432.1 - 7.6e-05 21.6 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 CEG35432.1 - 0.00043 19.6 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 CEG35432.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 CEG35432.1 - 0.032 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG35432.1 - 0.13 12.9 0.0 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family CTK3 PF12243.8 CEG35433.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Retrotran_gag_2 PF14223.6 CEG35437.1 - 2.3e-08 33.8 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HRDC PF00570.23 CEG35439.1 - 2e-10 40.5 0.0 5.4e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 HRDC domain KIX_2 PF16987.5 CEG35439.1 - 0.0029 17.6 0.3 0.0078 16.2 0.1 1.9 2 0 0 2 2 2 1 KIX domain KIX PF02172.16 CEG35439.1 - 0.079 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 KIX domain DUF1501 PF07394.12 CEG35439.1 - 0.095 11.7 1.3 0.18 10.8 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RelB_transactiv PF16181.5 CEG35439.1 - 0.1 12.8 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 RelB transactivation domain TFIIA PF03153.13 CEG35439.1 - 0.31 11.0 14.4 0.044 13.8 7.3 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Metal_resist PF13801.6 CEG35439.1 - 0.56 10.4 4.9 1.8 8.8 4.9 1.9 1 0 0 1 1 1 0 Heavy-metal resistance Tup_N PF08581.10 CEG35439.1 - 1.1 9.6 7.5 1.6 9.1 1.5 2.8 1 1 1 2 2 2 0 Tup N-terminal AAA PF00004.29 CEG35440.1 - 9.2e-46 155.5 0.0 3.2e-33 115.0 0.0 2.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG35440.1 - 1.5e-14 53.5 2.4 6.1e-10 38.8 0.4 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEG35440.1 - 7.3e-09 36.2 6.7 0.00086 19.7 0.1 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CEG35440.1 - 1.2e-07 32.0 0.0 0.00047 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEG35440.1 - 4.7e-06 26.9 0.7 0.0054 17.0 0.1 3.8 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 CEG35440.1 - 6.3e-05 23.5 0.5 0.061 13.8 0.2 2.6 2 1 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 CEG35440.1 - 0.00027 20.5 0.0 0.055 13.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CEG35440.1 - 0.00032 20.7 0.0 0.005 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEG35440.1 - 0.00062 19.0 0.3 0.41 9.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 CEG35440.1 - 0.00097 18.8 0.8 2.2 8.1 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain TsaE PF02367.17 CEG35440.1 - 0.0012 18.9 0.6 0.0062 16.5 0.0 2.4 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CEG35440.1 - 0.0017 18.4 0.4 0.047 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CEG35440.1 - 0.0018 18.2 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 CEG35440.1 - 0.0019 18.1 2.9 0.77 9.7 0.1 3.9 2 2 1 3 3 3 1 NACHT domain Sigma54_activat PF00158.26 CEG35440.1 - 0.0021 17.8 0.1 0.67 9.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 CEG35440.1 - 0.0024 18.0 0.0 0.065 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CEG35440.1 - 0.0026 17.0 0.4 0.1 11.8 0.1 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 CEG35440.1 - 0.003 17.9 0.1 0.092 13.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 CEG35440.1 - 0.0044 16.8 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEG35440.1 - 0.0071 15.8 2.0 0.75 9.1 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CEG35440.1 - 0.011 15.6 1.2 1.4 8.8 0.2 2.5 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 CEG35440.1 - 0.025 13.9 0.3 0.22 10.8 0.0 2.5 3 0 0 3 3 3 0 KaiC RuvB_N PF05496.12 CEG35440.1 - 0.033 13.9 0.1 0.39 10.4 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CEG35440.1 - 0.039 14.2 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEG35440.1 - 0.062 12.3 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 CEG35440.1 - 0.094 13.3 0.0 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CEG35441.1 - 5.6e-37 127.5 0.0 1e-26 93.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35441.1 - 1.6e-14 53.8 0.0 3.3e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DHOR PF06537.11 CEG35441.1 - 0.16 10.5 0.1 0.27 9.8 0.1 1.3 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase Methyltransf_16 PF10294.9 CEG35442.1 - 9.6e-26 90.6 0.0 1.9e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase TPR_2 PF07719.17 CEG35442.1 - 4.7e-06 26.3 8.5 0.00028 20.8 1.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG35442.1 - 0.00036 20.2 7.0 0.0058 16.4 1.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35442.1 - 0.0033 17.5 6.6 0.016 15.4 1.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG35442.1 - 0.0051 16.5 1.7 0.012 15.3 1.7 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.6 CEG35442.1 - 0.0093 16.2 1.0 0.0093 16.2 1.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG35442.1 - 0.032 14.8 5.5 2.2 8.8 2.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35442.1 - 0.044 13.7 0.4 0.044 13.7 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 CEG35442.1 - 0.13 12.1 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TPR_7 PF13176.6 CEG35442.1 - 0.2 11.8 2.6 0.24 11.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG35442.1 - 0.26 12.2 3.6 5.5 8.1 0.3 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG35442.1 - 1.3 9.8 10.6 1.8 9.3 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 CEG35443.1 - 2.9e-09 37.0 0.0 5.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG35443.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain MccV PF17508.2 CEG35444.1 - 0.028 15.0 0.0 0.032 14.8 0.0 1.1 1 0 0 1 1 1 0 Microcin V bacteriocin V_ATPase_I PF01496.19 CEG35445.1 - 3.9e-278 924.8 0.0 4.8e-278 924.5 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HWE_HK PF07536.14 CEG35445.1 - 0.77 10.5 2.3 32 5.3 0.1 3.0 3 0 0 3 3 3 0 HWE histidine kinase TPR_1 PF00515.28 CEG35448.1 - 1.1e-20 72.6 10.5 1.1e-07 31.3 1.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat Prefoldin PF02996.17 CEG35448.1 - 7.8e-18 64.5 1.3 7.8e-18 64.5 1.3 2.5 3 0 0 3 3 3 1 Prefoldin subunit TPR_2 PF07719.17 CEG35448.1 - 5.5e-13 48.0 15.5 1.4e-07 31.1 1.5 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35448.1 - 4e-10 39.1 11.1 6.9e-05 22.7 0.6 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG35448.1 - 1.5e-07 31.0 7.7 0.0026 17.4 0.4 3.2 1 1 2 3 3 3 2 TPR repeat TPR_17 PF13431.6 CEG35448.1 - 3e-06 27.2 4.2 0.0033 17.7 0.4 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG35448.1 - 0.00016 21.7 3.5 0.0013 18.9 1.2 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG35448.1 - 0.0014 18.9 7.3 0.0014 18.9 7.3 3.5 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG35448.1 - 0.0044 17.7 2.6 0.36 11.8 0.4 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 CEG35448.1 - 0.012 15.7 6.4 0.064 13.3 0.9 3.7 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 CEG35448.1 - 0.022 15.4 10.3 0.27 11.9 0.3 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Prefoldin_3 PF13758.6 CEG35448.1 - 0.025 14.6 0.0 0.025 14.6 0.0 2.8 1 1 2 3 3 3 0 Prefoldin subunit TPR_7 PF13176.6 CEG35448.1 - 0.03 14.3 4.8 0.83 9.8 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3835 PF12927.7 CEG35448.1 - 0.037 14.9 0.0 0.037 14.9 0.0 4.0 3 1 1 4 4 3 0 Domain of unknown function (DUF3835) DUF2813 PF11398.8 CEG35448.1 - 0.042 13.1 4.9 0.076 12.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) LMBR1 PF04791.16 CEG35448.1 - 0.049 12.5 7.3 0.07 12.0 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_3 PF07720.12 CEG35448.1 - 0.12 12.4 9.7 0.72 9.9 1.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35448.1 - 0.14 12.1 7.4 0.63 10.0 1.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG35448.1 - 0.15 12.3 12.0 0.027 14.7 6.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEG35448.1 - 5 7.7 13.0 13 6.3 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_primase_S PF01896.19 CEG35449.1 - 6.3e-55 185.9 0.0 1.1e-54 185.2 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Ribosomal_S8e PF01201.22 CEG35450.1 - 1.5e-50 170.9 2.7 2.3e-50 170.3 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2877 PF11392.8 CEG35451.1 - 0.077 13.7 0.0 0.14 12.8 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2877) TRM PF02005.16 CEG35452.1 - 2e-111 372.8 0.0 2.4e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CEG35452.1 - 3.9e-05 23.5 0.0 6.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CEG35452.1 - 0.032 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MA3 PF02847.17 CEG35453.1 - 2.5e-29 101.5 3.2 1e-14 54.4 0.1 4.1 3 1 1 4 4 4 2 MA3 domain MIF4G PF02854.19 CEG35453.1 - 3.2e-29 102.1 1.2 4.9e-18 65.6 0.0 3.0 2 0 0 2 2 2 2 MIF4G domain CNOT1_CAF1_bind PF16415.5 CEG35453.1 - 0.073 12.4 0.4 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Pet100 PF09803.9 CEG35453.1 - 0.58 10.7 2.6 6.2 7.4 1.1 2.7 2 0 0 2 2 2 0 Pet100 fn3 PF00041.21 CEG35454.1 - 0.00011 22.5 0.1 0.00014 22.1 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain DUF1804 PF08822.11 CEG35454.1 - 0.14 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Hydrolase_4 PF12146.8 CEG35458.1 - 6.1e-44 150.1 0.1 1.4e-30 106.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG35458.1 - 5.9e-09 36.8 0.0 1.2e-08 35.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CEG35458.1 - 0.032 13.9 0.2 0.087 12.4 0.2 1.7 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 CEG35458.1 - 0.048 13.1 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEG35459.1 - 4e-41 140.8 1.1 7.8e-27 94.1 0.0 2.8 4 0 0 4 4 4 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG35459.1 - 3.7e-05 24.4 0.9 6.5e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Calici_coat_C PF08435.11 CEG35459.1 - 0.13 11.8 0.4 0.28 10.6 0.4 1.5 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal PAP_central PF04928.17 CEG35461.1 - 7.9e-96 319.8 0.0 1e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEG35461.1 - 4.2e-20 72.1 0.0 1.8e-11 43.9 0.1 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEG35461.1 - 1.4e-05 25.3 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain ECH_1 PF00378.20 CEG35462.1 - 1.4e-85 286.6 1.4 1.7e-85 286.4 1.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEG35462.1 - 6.9e-35 121.1 4.8 4.2e-32 111.9 0.5 2.3 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CEG35462.1 - 0.016 15.2 1.1 0.28 11.1 0.0 2.7 3 0 0 3 3 3 0 Peptidase family S49 DUF3813 PF12758.7 CEG35462.1 - 0.059 13.7 1.4 0.23 11.8 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) RPAP2_Rtr1 PF04181.13 CEG35463.1 - 2.5e-15 56.5 0.7 5.4e-15 55.5 0.7 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Rdx PF10262.9 CEG35463.1 - 0.037 14.2 0.2 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 Rdx family GN3L_Grn1 PF08701.11 CEG35464.1 - 4.1e-17 62.0 20.5 4.1e-17 62.0 20.5 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CEG35464.1 - 1.1e-15 57.7 0.1 1.6e-12 47.5 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG35464.1 - 2e-08 33.9 0.0 0.00016 21.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG35464.1 - 9.6e-07 28.9 0.2 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG35464.1 - 4.1e-05 23.2 0.1 0.015 14.9 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.21 CEG35464.1 - 0.00017 21.1 0.6 0.032 13.7 0.0 2.7 2 1 1 3 3 3 1 ADP-ribosylation factor family cobW PF02492.19 CEG35464.1 - 0.0013 18.3 1.9 0.097 12.2 0.1 3.2 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyri_tr2 PF15891.5 CEG35464.1 - 0.0015 18.8 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Dynamin_N PF00350.23 CEG35464.1 - 0.0018 18.4 3.0 0.029 14.4 0.1 3.3 2 2 1 3 3 3 1 Dynamin family MeaB PF03308.16 CEG35464.1 - 0.004 16.2 1.0 0.014 14.4 0.0 2.3 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NAD_binding_10 PF13460.6 CEG35464.1 - 0.012 15.5 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AIG1 PF04548.16 CEG35464.1 - 0.012 14.9 0.8 0.024 14.0 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 CEG35464.1 - 0.013 15.7 0.2 0.81 9.9 0.0 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CEG35464.1 - 0.074 13.1 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG35464.1 - 0.081 13.5 0.0 0.081 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Trm112p PF03966.16 CEG35465.1 - 8.9e-07 29.4 0.1 1.2e-06 29.0 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein TMF_TATA_bd PF12325.8 CEG35466.1 - 4.9e-23 81.5 15.3 4.9e-23 81.5 15.3 9.0 4 2 5 10 10 10 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CEG35466.1 - 1.1e-06 28.5 13.2 1.1e-06 28.5 13.2 11.1 7 4 2 10 10 10 5 TATA element modulatory factor 1 DNA binding ERM PF00769.19 CEG35466.1 - 0.0081 16.0 21.1 0.0081 16.0 21.1 6.3 1 1 6 7 7 7 1 Ezrin/radixin/moesin family Spore_Cse60 PF10957.8 CEG35466.1 - 0.13 12.3 1.4 21 5.2 0.0 3.0 2 0 0 2 2 2 0 Sporulation protein Cse60 DUF787 PF05619.11 CEG35466.1 - 7 5.7 10.6 0.23 10.5 1.5 2.7 2 1 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF787) YABBY PF04690.13 CEG35469.1 - 0.074 13.6 0.1 0.096 13.2 0.1 1.2 1 0 0 1 1 1 0 YABBY protein WD40 PF00400.32 CEG35471.1 - 2.5e-14 53.4 0.9 7.7e-06 26.6 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35471.1 - 0.0026 18.0 0.0 8.6 6.7 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CEG35472.1 - 1e-76 257.8 0.0 1.4e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35472.1 - 2.4e-35 122.1 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG35472.1 - 1.8e-05 24.2 0.3 2.9e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG35472.1 - 0.00013 22.0 0.0 0.0018 18.3 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEG35472.1 - 0.0028 17.3 0.1 0.0056 16.3 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEG35472.1 - 0.0054 15.6 0.2 0.013 14.3 0.0 1.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CEG35472.1 - 0.0057 16.0 0.0 0.028 13.8 0.0 2.1 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 CEG35472.1 - 0.0098 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 CEG35472.1 - 0.12 11.9 1.8 0.093 12.3 0.3 1.5 2 0 0 2 2 2 0 RIO1 family Methyltransf_34 PF11312.8 CEG35473.1 - 0.1 11.9 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Cellulase PF00150.18 CEG35474.1 - 0.0019 17.7 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) bZIP_Maf PF03131.17 CEG35476.1 - 0.058 13.9 3.7 0.13 12.8 3.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_S4Pg PF11993.8 CEG35476.1 - 0.068 13.2 0.3 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal S4P (gammaproteobacterial) Occludin_ELL PF07303.13 CEG35476.1 - 1.1 10.0 7.1 1.8 9.3 7.1 1.3 1 0 0 1 1 1 0 Occludin homology domain Tup_N PF08581.10 CEG35476.1 - 1.3 9.4 7.1 4.1 7.8 1.3 2.3 1 1 0 2 2 2 0 Tup N-terminal Cep57_MT_bd PF06657.13 CEG35477.1 - 0.02 15.3 0.6 0.08 13.4 0.0 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ABC_tran_CTD PF16326.5 CEG35477.1 - 0.051 13.8 3.3 0.71 10.2 0.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain PEPcase PF00311.17 CEG35477.1 - 0.095 10.8 4.5 0.11 10.5 4.5 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RCDG1 PF15725.5 CEG35477.1 - 0.1 13.0 0.5 0.16 12.4 0.5 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF2207 PF09972.9 CEG35477.1 - 0.15 10.8 1.2 0.18 10.6 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) bZIP_1 PF00170.21 CEG35477.1 - 0.16 12.1 15.7 0.08 13.1 10.9 2.4 1 1 1 2 2 2 0 bZIP transcription factor bZIP_Maf PF03131.17 CEG35477.1 - 0.43 11.1 13.5 0.61 10.6 3.3 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor LMBR1 PF04791.16 CEG35477.1 - 2 7.3 3.4 2.2 7.1 3.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein TIP49 PF06068.13 CEG35479.1 - 6.9e-172 571.5 0.2 8.5e-172 571.2 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEG35479.1 - 1.4e-22 79.5 0.1 3.8e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CEG35479.1 - 1.1e-08 35.6 0.2 1.4e-05 25.5 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG35479.1 - 1.5e-08 34.6 0.2 2.3e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG35479.1 - 2.9e-06 27.6 0.1 0.016 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG35479.1 - 0.00063 20.2 0.4 0.0082 16.5 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEG35479.1 - 0.0012 18.9 0.1 0.082 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CEG35479.1 - 0.0012 19.1 0.5 0.93 9.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEG35479.1 - 0.0044 16.4 0.3 0.12 11.7 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CEG35479.1 - 0.0071 16.6 0.1 0.022 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG35479.1 - 0.0087 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CEG35479.1 - 0.0095 15.7 0.1 5 6.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 CEG35479.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HET-s_218-289 PF11558.8 CEG35479.1 - 0.034 14.2 0.3 0.12 12.5 0.0 2.1 2 0 0 2 2 1 0 Het-s 218-289 Zeta_toxin PF06414.12 CEG35479.1 - 0.055 12.8 0.2 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CEG35479.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CEG35479.1 - 0.098 12.6 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 CEG35479.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CEG35479.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain LNS2 PF08235.13 CEG35480.1 - 3.7e-44 150.9 0.0 6.5e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CEG35480.1 - 6.2e-10 39.0 0.0 3.1e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CEG35480.1 - 0.013 15.1 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ALS_ss_C PF10369.9 CEG35481.1 - 2.1e-24 85.5 0.4 5.8e-24 84.1 0.1 1.9 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 CEG35481.1 - 5e-11 42.2 0.6 1.4e-10 40.8 0.2 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 CEG35481.1 - 7.8e-07 28.8 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain Myb_DNA-binding PF00249.31 CEG35483.1 - 0.017 15.3 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MAGE PF01454.19 CEG35483.1 - 0.029 14.1 1.9 0.033 13.9 1.9 1.1 1 0 0 1 1 1 0 MAGE family Myb_DNA-bind_6 PF13921.6 CEG35483.1 - 0.08 13.2 0.7 0.15 12.4 0.6 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain PRKG1_interact PF15898.5 CEG35483.1 - 1.2 10.1 8.9 2.1 9.3 8.9 1.4 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Rpr2 PF04032.16 CEG35486.1 - 5e-13 49.1 1.6 5e-13 49.1 1.6 2.8 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4674 PF15719.5 CEG35486.1 - 0.026 14.6 15.3 0.062 13.3 15.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) Zn_Tnp_IS91 PF14319.6 CEG35486.1 - 0.12 12.4 2.5 0.56 10.3 0.0 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain zf_UBZ PF18439.1 CEG35486.1 - 0.31 10.7 1.6 13 5.5 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CEG35486.1 - 0.87 9.6 4.4 0.67 9.9 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbon domain ABC_tran PF00005.27 CEG35487.1 - 3.3e-18 66.5 0.0 5.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEG35487.1 - 2.6e-08 34.0 3.2 0.00058 19.8 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG35487.1 - 4.3e-06 26.3 1.0 3.8e-05 23.2 1.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 CEG35487.1 - 0.00052 19.7 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CEG35487.1 - 0.00061 19.6 0.2 0.0045 16.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG35487.1 - 0.00098 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 CEG35487.1 - 0.0017 18.1 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CEG35487.1 - 0.0022 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG35487.1 - 0.0087 16.5 0.4 0.018 15.5 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEG35487.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CEG35487.1 - 0.04 14.4 0.1 0.048 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEG35487.1 - 0.048 13.7 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 CEG35487.1 - 0.081 12.6 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CEG35487.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CEG35487.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 CEG35487.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CEG35487.1 - 0.18 12.0 0.9 0.79 10.0 0.9 1.9 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.15 CEG35487.1 - 0.21 11.8 0.3 0.83 9.9 0.0 1.9 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Dynamin_N PF00350.23 CEG35487.1 - 0.23 11.5 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Dynamin family Pkinase PF00069.25 CEG35488.1 - 2.7e-67 226.9 0.0 4.5e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35488.1 - 7.7e-32 110.6 0.0 1.3e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG35488.1 - 1.3e-09 38.5 0.7 5.7e-09 36.4 0.0 2.5 3 0 0 3 3 3 1 PH domain Kdo PF06293.14 CEG35488.1 - 5.2e-05 22.7 0.5 9.7e-05 21.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 CEG35488.1 - 0.0014 18.9 0.0 0.0089 16.3 0.0 2.4 3 0 0 3 3 3 1 C2 domain Haspin_kinase PF12330.8 CEG35488.1 - 0.0037 16.3 0.1 0.0069 15.4 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG35488.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEG35488.1 - 0.063 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Eaf7 PF07904.13 CEG35489.1 - 0.088 13.2 0.3 0.17 12.3 0.3 1.6 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF760 PF05542.11 CEG35489.1 - 0.11 12.9 0.0 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF760) COMM_domain PF07258.14 CEG35490.1 - 0.00013 22.0 0.0 0.003 17.7 0.0 2.4 2 0 0 2 2 2 1 COMM domain Pollen_allerg_1 PF01357.21 CEG35490.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Pollen allergen Tub PF01167.18 CEG35491.1 - 6.2e-45 153.8 0.0 1.2e-44 152.9 0.0 1.5 1 1 0 1 1 1 1 Tub family PDZ_6 PF17820.1 CEG35491.1 - 2e-08 34.0 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG35491.1 - 0.003 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 CEG35492.1 - 0.00056 20.8 0.0 0.001 20.0 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Nucleoporin_C PF03177.14 CEG35495.1 - 2.7e-05 23.2 8.5 7.9e-05 21.6 8.5 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal ArfGap PF01412.18 CEG35496.1 - 3.9e-35 120.5 0.0 6.4e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 CEG35496.1 - 3.4e-11 43.3 0.0 5.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain VPS13_C PF16909.5 CEG35496.1 - 0.00038 20.3 0.7 0.00088 19.1 0.7 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CEG35496.1 - 0.0046 17.3 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Antimicrobial_2 PF08023.12 CEG35496.1 - 0.16 12.5 0.4 1.4 9.5 0.2 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide EF-hand_7 PF13499.6 CEG35497.1 - 1.5e-13 51.0 0.1 6.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG35497.1 - 1.2e-12 46.7 0.1 0.0011 18.7 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CEG35497.1 - 1.4e-12 46.2 0.0 1.8e-05 23.9 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CEG35497.1 - 5.3e-07 29.4 0.0 0.0016 18.2 0.0 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG35497.1 - 1.2e-05 24.5 1.0 0.001 18.5 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_13 PF17958.1 CEG35497.1 - 0.047 13.5 0.0 5.2 7.0 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain B9-C2 PF07162.11 CEG35498.1 - 1.3e-30 106.8 0.2 2.9e-30 105.7 0.2 1.6 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF1713 PF08213.11 CEG35498.1 - 7.2e-10 38.6 13.4 7.2e-10 38.6 13.4 2.6 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) FHA PF00498.26 CEG35499.1 - 4.9e-10 39.6 0.4 1.3e-09 38.2 0.4 1.8 1 0 0 1 1 1 1 FHA domain AAA_16 PF13191.6 CEG35499.1 - 5.5e-06 26.9 0.1 2.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CEG35499.1 - 0.00049 19.9 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 CEG35499.1 - 0.0033 17.4 0.0 0.0093 15.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CEG35499.1 - 0.004 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEG35499.1 - 0.013 15.9 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG35499.1 - 0.029 14.4 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CEG35499.1 - 0.059 12.5 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CEG35499.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CEG35499.1 - 0.19 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPSF73-100_C PF11718.8 CEG35500.1 - 1.4e-40 139.2 0.7 4.1e-40 137.7 0.5 1.9 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CEG35500.1 - 2.8e-31 108.1 0.0 6e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CEG35500.1 - 2.6e-22 79.2 0.0 6.2e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CEG35500.1 - 3.2e-20 73.0 0.3 8.2e-20 71.6 0.2 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CEG35500.1 - 5.2e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CEG35500.1 - 1.2e-09 38.0 0.2 2.9e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEG35500.1 - 8.1e-06 25.8 0.1 3.6e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CEG35500.1 - 9.3e-06 25.0 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Sulfotransfer_1 PF00685.27 CEG35502.1 - 3.6e-10 39.8 1.6 3.8e-09 36.4 1.6 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEG35502.1 - 4e-09 37.2 0.6 3.5e-07 30.8 0.7 2.2 1 1 0 2 2 2 2 Sulfotransferase family SVIP PF15811.5 CEG35505.1 - 8.4e-05 23.0 5.9 0.00015 22.1 5.9 1.4 1 0 0 1 1 1 1 Small VCP/p97-interacting protein CBS PF00571.28 CEG35506.1 - 8.4e-26 90.2 3.1 2.9e-06 27.6 0.0 4.5 4 1 0 4 4 4 4 CBS domain Radical_SAM PF04055.21 CEG35510.1 - 1.1e-11 45.4 0.0 1.9e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 CEG35510.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain AMIN PF11741.8 CEG35510.1 - 0.0052 16.9 0.0 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 AMIN domain IQ PF00612.27 CEG35511.1 - 1.9e-06 27.1 21.8 0.11 12.4 0.2 5.4 4 0 0 4 4 4 4 IQ calmodulin-binding motif LRR_9 PF14580.6 CEG35511.1 - 0.029 13.9 0.7 0.073 12.6 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Amidohydro_1 PF01979.20 CEG35511.1 - 0.084 12.2 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family PLU-1 PF08429.11 CEG35512.1 - 1.1e-29 103.7 47.7 9.9e-08 31.5 1.4 6.9 3 1 2 6 6 6 5 PLU-1-like protein PHD PF00628.29 CEG35512.1 - 2.1e-07 30.7 2.6 5e-07 29.5 2.6 1.6 1 0 0 1 1 1 1 PHD-finger ELM2 PF01448.24 CEG35512.1 - 6.4e-06 26.8 0.1 5.8e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 ELM2 domain zf-PHD-like PF15446.6 CEG35512.1 - 0.16 11.6 4.1 0.47 10.1 2.8 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_3 PF13922.6 CEG35512.1 - 0.19 12.1 1.5 0.77 10.2 1.5 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DIL PF01843.19 CEG35512.1 - 5.8 7.2 7.0 2 8.8 1.1 3.5 4 0 0 4 4 4 0 DIL domain Band_7 PF01145.25 CEG35513.1 - 2.5e-30 105.8 0.0 2.5e-30 105.8 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CEG35513.1 - 4e-27 94.1 0.1 9.5e-27 92.9 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 CEG35513.1 - 0.012 15.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 SPFH domain-Band 7 family MutS_V PF00488.21 CEG35514.1 - 7.4e-78 260.9 0.1 1.3e-77 260.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEG35514.1 - 1e-26 94.4 0.5 2.2e-26 93.3 0.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CEG35514.1 - 1.2e-08 35.1 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV NTPase_1 PF03266.15 CEG35514.1 - 0.0079 16.1 0.6 4.6 7.1 0.0 3.4 3 0 0 3 3 3 2 NTPase AAA_28 PF13521.6 CEG35514.1 - 0.012 15.8 0.1 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CEG35514.1 - 0.039 13.6 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MutS_II PF05188.17 CEG35514.1 - 0.44 10.8 3.4 1.4 9.2 0.1 3.2 4 0 0 4 4 4 0 MutS domain II Nefa_Nip30_N PF10187.9 CEG35516.1 - 3.5e-17 62.7 0.9 7e-17 61.7 0.9 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 SNase PF00565.17 CEG35517.1 - 7.1e-54 180.9 0.2 8.5e-12 45.5 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CEG35517.1 - 3.4e-16 59.4 0.0 7.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Tudor domain FKBP_C PF00254.28 CEG35518.1 - 1.7e-23 82.8 0.1 3.9e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CEG35518.1 - 4.9e-09 35.6 2.8 0.0005 19.8 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG35518.1 - 7.6e-06 25.7 2.0 0.089 12.9 0.4 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG35518.1 - 0.0039 16.8 0.1 0.76 9.5 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 CEG35518.1 - 0.0057 17.1 1.7 8.1 7.0 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35518.1 - 0.02 15.1 7.2 1.2 9.6 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0172 PF03665.13 CEG35518.1 - 0.19 11.7 0.2 0.19 11.7 0.2 1.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) BK_channel_a PF03493.18 CEG35521.1 - 5.7e-20 71.3 0.0 2.4e-18 66.1 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 CEG35521.1 - 0.0097 16.2 0.1 1.6 9.0 0.0 2.9 2 0 0 2 2 2 2 TrkA-N domain RecA PF00154.21 CEG35522.1 - 9.8e-133 441.5 2.1 1.2e-132 441.3 2.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 CEG35522.1 - 2.9e-12 46.4 0.4 4e-11 42.7 0.4 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 CEG35522.1 - 4.9e-09 35.9 0.1 8.9e-07 28.5 0.1 2.8 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 CEG35522.1 - 5.5e-05 23.2 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CEG35522.1 - 0.0003 20.4 0.4 0.0079 15.8 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG35522.1 - 0.0015 19.0 0.1 0.0035 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CEG35522.1 - 0.0038 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEG35522.1 - 0.021 15.4 0.1 0.054 14.0 0.0 1.9 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 CEG35522.1 - 0.021 15.2 0.1 0.06 13.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEG35522.1 - 0.025 14.6 0.0 0.96 9.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain CobU PF02283.16 CEG35522.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase PF00069.25 CEG35523.1 - 3.3e-53 180.7 0.0 5.4e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cyclin_N PF00134.23 CEG35523.1 - 1e-33 115.8 5.4 7.5e-33 113.0 2.4 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEG35523.1 - 4.8e-22 78.3 0.3 1.1e-21 77.2 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase_Tyr PF07714.17 CEG35523.1 - 6.6e-13 48.5 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 CEG35523.1 - 5.7e-08 32.5 0.0 8.7e-07 28.7 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEG35523.1 - 0.00028 20.7 0.6 0.00083 19.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain Kdo PF06293.14 CEG35523.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HECT PF00632.25 CEG35524.1 - 5.1e-71 239.7 0.0 7.6e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 CEG35524.1 - 0.0014 17.9 4.3 0.0022 17.2 4.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CEG35524.1 - 0.04 13.3 2.1 0.14 11.5 2.1 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CEG35524.1 - 1.4 9.1 3.3 4 7.6 0.4 2.6 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Cupin_4 PF08007.12 CEG35525.1 - 9.8e-05 22.0 1.6 0.00025 20.6 0.0 2.4 2 2 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 CEG35525.1 - 0.055 13.2 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Glyco_transf_22 PF03901.17 CEG35526.1 - 3.3e-47 161.6 26.9 4.6e-47 161.2 26.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Choline_transpo PF04515.12 CEG35527.1 - 6.1e-95 318.2 25.2 6.1e-95 318.2 25.2 2.6 3 0 0 3 3 3 1 Plasma-membrane choline transporter MRAP PF15183.6 CEG35527.1 - 4.6 7.2 8.3 0.2 11.6 1.2 2.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family ANAPC4_WD40 PF12894.7 CEG35528.1 - 1e-10 41.8 0.1 0.0084 16.4 0.0 4.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG35528.1 - 0.00018 22.2 2.3 1.4 9.9 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Glyco_hydro_31 PF01055.26 CEG35529.1 - 2.3e-113 379.7 0.0 4.8e-87 293.0 0.0 2.1 1 1 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CEG35529.1 - 1.8e-26 92.6 0.0 4.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CEG35529.1 - 6.4e-07 29.2 14.5 1.5e-05 24.8 4.5 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CEG35529.1 - 1.1e-06 28.9 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CEG35529.1 - 0.0014 18.8 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Fibrillin_U_N PF18193.1 CEG35529.1 - 0.15 12.2 0.3 0.38 10.9 0.3 1.7 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain SAM_1 PF00536.30 CEG35530.1 - 4.7e-10 39.8 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG35530.1 - 2.4e-09 37.2 0.0 5.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_3 PF07859.13 CEG35531.1 - 1.4e-38 132.9 0.0 2.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEG35531.1 - 6.6e-09 35.1 0.0 9.8e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 CEG35531.1 - 0.0058 15.6 0.3 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family DUF3168 PF11367.8 CEG35532.1 - 0.031 14.5 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) DUF1411 PF07199.11 CEG35532.1 - 0.68 9.6 10.7 1.8 8.2 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1411) Enkurin PF13864.6 CEG35535.1 - 1.6e-24 86.2 5.9 4.9e-24 84.6 0.3 2.6 2 0 0 2 2 2 1 Calmodulin-binding SR-25 PF10500.9 CEG35535.1 - 0.013 15.1 12.7 0.014 15.1 11.2 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein YfhO PF09586.10 CEG35535.1 - 0.077 11.2 1.7 0.096 10.9 1.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO zf-C4H2 PF10146.9 CEG35535.1 - 0.37 11.1 11.2 0.24 11.7 9.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein F420_oxidored PF03807.17 CEG35537.1 - 1.1e-10 41.9 0.0 3.3e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 CEG35537.1 - 5.1e-07 29.9 0.0 8.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Semialdhyde_dh PF01118.24 CEG35537.1 - 8.7e-05 22.9 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEG35537.1 - 0.00071 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CEG35537.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3522 PF12036.8 CEG35537.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Med17 PF10156.9 CEG35538.1 - 5.2e-06 25.4 0.4 2.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Subunit 17 of Mediator complex Aldo_ket_red PF00248.21 CEG35539.1 - 2.3e-29 102.5 0.6 4.1e-14 52.5 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family HATPase_c PF02518.26 CEG35540.1 - 6.1e-12 46.0 0.0 2e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEG35540.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.13 CEG35541.1 - 0.0015 18.3 0.0 0.0061 16.3 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CEG35541.1 - 0.0016 19.1 0.7 0.005 17.5 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family HEAT PF02985.22 CEG35541.1 - 0.72 10.3 2.7 33 5.1 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 CEG35541.1 - 5.3 7.2 10.1 15 5.8 0.1 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Hydrolase_4 PF12146.8 CEG35544.1 - 0.0053 16.1 0.0 0.25 10.6 0.0 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DELLA PF12041.8 CEG35544.1 - 0.1 12.5 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal TBD PF12845.7 CEG35545.1 - 0.079 12.9 0.0 0.4 10.6 0.0 2.2 1 0 0 1 1 1 0 TBD domain IFRD PF05004.13 CEG35545.1 - 0.16 11.0 2.2 0.95 8.5 0.1 2.6 1 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) TGase_elicitor PF16683.5 CEG35546.1 - 2.2e-83 280.0 0.0 2.8e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor Presenilin PF01080.17 CEG35546.1 - 0.51 9.1 2.2 0.66 8.7 2.2 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 CEG35546.1 - 0.84 9.0 6.5 1.1 8.6 6.5 1.1 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 CEG35549.1 - 8.5e-30 103.9 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG35549.1 - 2.8e-25 89.2 0.0 5.5e-25 88.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 CEG35549.1 - 2.1e-13 50.2 21.1 7.2e-05 23.1 0.6 5.7 3 3 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG35549.1 - 3.7e-08 33.0 15.0 0.00029 20.5 0.4 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CEG35549.1 - 3.2e-06 26.8 7.8 8.4 6.7 0.0 5.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CEG35549.1 - 0.077 13.6 11.0 66 4.7 0.0 6.9 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_5 PF13306.6 CEG35549.1 - 0.13 12.3 5.4 0.21 11.6 3.3 2.2 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) WD40 PF00400.32 CEG35551.1 - 0.0091 16.8 2.5 0.57 11.2 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Ion_trans PF00520.31 CEG35552.1 - 2.8e-37 128.3 52.4 9.4e-19 67.6 20.8 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 CEG35552.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Exonuc_VII_L PF02601.15 CEG35552.1 - 5.9 6.4 7.2 13 5.2 7.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_2 PF13639.6 CEG35553.1 - 6.5e-09 36.0 10.0 1.5e-08 34.8 10.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG35553.1 - 6.4e-07 29.1 6.7 1.3e-06 28.2 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG35553.1 - 1e-06 28.5 8.8 2.2e-06 27.4 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG35553.1 - 1.1e-06 28.8 7.2 2.7e-06 27.5 7.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG35553.1 - 9.5e-06 25.4 10.1 1.9e-05 24.4 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG35553.1 - 3.1e-05 23.7 6.9 6.5e-05 22.7 6.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEG35553.1 - 5.5e-05 23.1 5.7 0.00014 21.8 5.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEG35553.1 - 0.00012 22.0 6.1 0.0012 18.8 3.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG35553.1 - 0.0015 18.4 11.7 0.057 13.4 11.9 2.5 1 1 1 2 2 2 1 zinc-RING finger domain PX PF00787.24 CEG35553.1 - 0.003 17.5 0.3 0.0087 16.0 0.3 1.7 1 0 0 1 1 1 1 PX domain Zn_ribbon_17 PF17120.5 CEG35553.1 - 0.03 13.9 5.9 0.091 12.4 5.9 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CEG35553.1 - 0.056 13.3 6.5 0.14 12.0 6.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CEG35553.1 - 0.5 10.3 8.3 2 8.3 8.3 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 CEG35553.1 - 6.6 7.0 10.8 9.4 6.4 8.9 2.3 2 0 0 2 2 2 0 RING-variant domain TBP PF00352.21 CEG35554.1 - 1.2e-40 137.4 0.1 3.4e-25 87.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CEG35554.1 - 0.066 13.3 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) LmjF365940-deam PF14421.6 CEG35555.1 - 4.4e-67 225.4 0.5 7.3e-67 224.7 0.5 1.4 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Ank_2 PF12796.7 CEG35556.1 - 2.4e-34 117.8 13.0 5e-13 49.5 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG35556.1 - 3.2e-26 91.0 6.4 6.2e-08 32.8 0.1 5.7 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CEG35556.1 - 2.4e-24 84.7 4.3 8.4e-07 29.2 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 CEG35556.1 - 2.4e-24 85.4 2.0 4.8e-10 39.8 0.0 4.8 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG35556.1 - 2e-21 73.8 0.8 0.0063 16.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat PAP_assoc PF03828.19 CEG35558.1 - 1.7e-12 47.3 0.1 3.1e-11 43.3 0.0 3.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase zf-CCHC_3 PF13917.6 CEG35558.1 - 0.045 13.7 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4701 PF15773.5 CEG35559.1 - 0.065 12.2 8.0 0.037 13.0 6.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4701) zf-C2H2_6 PF13912.6 CEG35559.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger AT_hook PF02178.19 CEG35559.1 - 0.21 11.6 6.0 0.22 11.5 1.1 3.0 2 0 0 2 2 2 0 AT hook motif SNARE PF05739.19 CEG35560.1 - 5.7e-06 26.2 1.7 9.5e-06 25.5 0.6 1.8 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 CEG35560.1 - 0.0031 17.3 0.9 0.0033 17.2 0.9 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 YjcZ PF13990.6 CEG35560.1 - 0.0039 16.6 0.3 0.0046 16.4 0.3 1.0 1 0 0 1 1 1 1 YjcZ-like protein TRIQK PF15168.6 CEG35560.1 - 0.0074 16.2 0.7 0.0074 16.2 0.7 1.5 1 1 1 2 2 2 1 Triple QxxK/R motif-containing protein family DUF4407 PF14362.6 CEG35560.1 - 0.024 14.0 0.2 0.028 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 CEG35560.1 - 0.047 13.5 3.1 0.078 12.8 2.4 1.7 1 1 1 2 2 2 0 Synaptobrevin MCU PF04678.13 CEG35560.1 - 0.05 13.7 0.2 0.057 13.5 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RasGAP_C PF03836.15 CEG35560.1 - 0.07 13.3 2.0 0.093 12.9 2.0 1.1 1 0 0 1 1 1 0 RasGAP C-terminus Phage_Coat_Gp8 PF05371.12 CEG35560.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Phage major coat protein, Gp8 DUF5527 PF17665.1 CEG35560.1 - 0.18 11.4 0.3 0.32 10.5 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Orf78 PF06024.12 CEG35560.1 - 0.62 10.4 4.3 0.31 11.4 1.7 1.7 1 1 1 2 2 2 0 Orf78 (ac78) Sec20 PF03908.13 CEG35560.1 - 0.91 9.5 4.9 1.7 8.6 3.5 1.9 1 1 1 2 2 2 0 Sec20 Phospholamban PF04272.14 CEG35560.1 - 8.1 6.0 9.0 0.71 9.4 1.9 2.5 2 1 1 3 3 3 0 Phospholamban WD40 PF00400.32 CEG35561.1 - 3.9e-16 59.2 10.2 0.0038 18.0 0.2 9.2 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35561.1 - 0.00011 22.5 0.0 2.6 8.4 0.0 5.6 5 2 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG35561.1 - 0.00038 19.5 0.1 0.039 12.9 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Astro_capsid_p PF12226.8 CEG35561.1 - 0.22 10.6 15.7 0.55 9.3 15.7 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAA_hydro_N_2 PF18288.1 CEG35561.1 - 0.47 10.9 2.4 6.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 NOA36 PF06524.12 CEG35561.1 - 0.86 8.9 17.6 2.5 7.4 17.6 1.7 1 0 0 1 1 1 0 NOA36 protein DUF1664 PF07889.12 CEG35561.1 - 1.6 8.8 7.6 1.2 9.2 1.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TFIIA PF03153.13 CEG35561.1 - 2.5 8.0 27.7 0.0093 16.0 12.1 2.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UreF PF01730.16 CEG35562.1 - 5.2e-26 91.8 1.0 7.6e-26 91.3 1.0 1.2 1 0 0 1 1 1 1 UreF DUF3269 PF11673.8 CEG35563.1 - 0.077 13.4 0.0 0.088 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) CATSPERD PF15020.6 CEG35564.1 - 0.014 13.7 0.1 0.018 13.3 0.1 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Serum_albumin PF00273.20 CEG35564.1 - 0.44 10.3 9.9 0.18 11.6 1.6 2.7 2 1 1 3 3 3 0 Serum albumin family KASH_CCD PF14662.6 CEG35564.1 - 0.58 10.0 10.6 0.21 11.4 5.7 2.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF962 PF06127.11 CEG35569.1 - 6.7e-15 54.9 3.6 1.3e-14 54.1 3.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ABC-3 PF00950.17 CEG35569.1 - 0.00018 21.1 1.9 0.00028 20.5 1.9 1.2 1 0 0 1 1 1 1 ABC 3 transport family DUF2690 PF10901.8 CEG35572.1 - 0.087 13.1 0.1 0.088 13.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2690) Pkinase PF00069.25 CEG35577.1 - 1.6e-24 86.7 0.0 5.7e-24 84.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35577.1 - 1.7e-19 70.1 0.0 8.2e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 CEG35577.1 - 7e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 CEG35577.1 - 0.0023 17.9 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rer1 PF03248.13 CEG35580.1 - 0.0056 16.4 0.1 0.0062 16.3 0.1 1.2 1 0 0 1 1 1 1 Rer1 family CaATP_NAI PF12515.8 CEG35581.1 - 0.093 12.4 1.5 0.65 9.7 0.5 2.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Abhydrolase_6 PF12697.7 CEG35582.1 - 0.00088 19.9 0.3 0.0082 16.8 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Snf7 PF03357.21 CEG35583.1 - 4.3e-40 137.1 19.9 6.3e-40 136.6 19.9 1.2 1 0 0 1 1 1 1 Snf7 GCH_III PF05165.12 CEG35583.1 - 0.0019 17.6 3.3 0.0022 17.3 0.5 2.0 1 1 1 2 2 2 1 GTP cyclohydrolase III Pollen_allerg_1 PF01357.21 CEG35583.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Pollen allergen Atg14 PF10186.9 CEG35583.1 - 0.17 10.9 4.7 0.24 10.4 4.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GLE1 PF07817.13 CEG35583.1 - 0.2 10.9 4.9 0.2 10.9 3.8 1.5 1 1 0 1 1 1 0 GLE1-like protein YlqD PF11068.8 CEG35583.1 - 0.24 11.8 18.4 0.085 13.2 9.0 2.2 1 1 1 2 2 2 0 YlqD protein DUF4854 PF16146.5 CEG35583.1 - 1.5 9.2 7.1 0.73 10.2 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) DUF4047 PF13256.6 CEG35583.1 - 1.9 8.7 10.7 0.91 9.7 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Mob1_phocein PF03637.17 CEG35584.1 - 4.4e-32 111.4 1.6 5.5e-32 111.1 1.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.25 CEG35585.1 - 1.7e-46 158.8 0.0 3.5e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35585.1 - 1.7e-17 63.6 0.0 3.3e-12 46.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Dicty_REP PF05086.12 CEG35585.1 - 0.6 8.0 3.4 0.85 7.5 3.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FYVE PF01363.21 CEG35587.1 - 1.7e-12 47.3 15.3 1.7e-12 47.3 15.3 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 CEG35587.1 - 0.0039 17.4 12.2 0.016 15.4 12.2 2.2 1 1 1 2 2 2 1 FYVE-type zinc finger DUF326 PF03860.16 CEG35587.1 - 1.3 9.1 3.8 3.7 7.6 3.8 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) OrfB_Zn_ribbon PF07282.11 CEG35587.1 - 8.3 6.4 8.6 1.1e+02 2.8 8.4 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain YhcG_C PF06250.11 CEG35593.1 - 0.065 13.1 0.2 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 YhcG PDDEXK nuclease domain Cutinase PF01083.22 CEG35594.1 - 8.3e-40 136.6 2.2 1e-39 136.3 2.2 1.1 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.22 CEG35595.1 - 7.1e-43 146.6 2.2 8.5e-43 146.4 2.2 1.0 1 0 0 1 1 1 1 Cutinase WD40 PF00400.32 CEG35596.1 - 1.8e-25 88.7 20.6 7.2e-06 26.7 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CEG35596.1 - 4.1e-23 81.4 3.7 1.3e-22 79.8 0.6 3.3 5 0 0 5 5 5 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CEG35596.1 - 0.0023 18.2 1.5 0.15 12.4 0.1 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_2 PF00703.21 CEG35596.1 - 0.096 13.4 0.2 0.3 11.8 0.2 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 CAF1C_H4-bd PF12265.8 CEG35597.1 - 2.3e-31 107.9 1.3 1e-29 102.6 0.1 3.6 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CEG35597.1 - 8.3e-30 102.4 20.2 1e-06 29.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 CEG35597.1 - 3e-07 30.5 0.5 0.0006 19.7 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CEG35597.1 - 0.00019 21.7 0.8 0.097 13.0 0.0 3.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Vps55 PF04133.14 CEG35598.1 - 1.1e-09 38.3 11.0 1.2e-09 38.1 11.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 zf-UBP PF02148.19 CEG35599.1 - 1.9e-19 69.7 6.6 6.2e-19 68.1 6.6 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 CEG35599.1 - 1.2e-16 60.8 0.2 2.4e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 CEG35599.1 - 1.1e-07 32.1 7.9 1.1e-07 32.1 7.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG35599.1 - 3.1e-07 30.1 6.5 3.1e-07 30.1 6.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG35599.1 - 8.5e-05 22.2 3.5 8.5e-05 22.2 3.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CEG35599.1 - 0.00023 21.4 5.5 0.00092 19.5 5.5 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG35599.1 - 0.00078 19.3 5.8 0.00078 19.3 5.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG35599.1 - 0.0029 17.4 15.5 0.013 15.3 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 CEG35599.1 - 0.0039 17.3 12.3 0.0084 16.2 12.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus zf-RING_UBOX PF13445.6 CEG35599.1 - 0.0076 16.3 2.1 0.0076 16.3 2.1 3.0 1 1 1 2 2 1 1 RING-type zinc-finger RRM_1 PF00076.22 CEG35599.1 - 0.089 12.6 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIN_12 PF16289.5 CEG35599.1 - 0.23 12.0 5.3 0.5 10.8 5.3 1.5 1 0 0 1 1 1 0 PIN domain zf-ANAPC11 PF12861.7 CEG35599.1 - 1.1 9.4 8.4 0.34 11.0 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.15 CEG35599.1 - 2 7.9 5.7 3.3 7.2 5.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_4 PF14570.6 CEG35599.1 - 2.8 7.8 7.7 0.96 9.3 4.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PX PF00787.24 CEG35601.1 - 1.4e-26 92.7 0.0 1.6e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CEG35601.1 - 3.2e-05 23.6 0.8 3.2e-05 23.6 0.8 2.5 3 0 0 3 3 3 2 Vps5 C terminal like BAR PF03114.18 CEG35601.1 - 5.2e-05 23.0 2.5 0.0001 22.0 2.5 1.4 1 0 0 1 1 1 1 BAR domain PCP PF02429.15 CEG35601.1 - 0.028 14.7 0.1 0.083 13.2 0.1 1.8 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein DUF3251 PF11622.8 CEG35601.1 - 0.079 12.6 1.7 0.21 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) SAM_KSR1 PF13543.6 CEG35601.1 - 0.21 11.7 1.1 0.44 10.7 0.2 1.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 PEPCK_ATP PF01293.20 CEG35602.1 - 1.6e-214 712.9 0.2 1.9e-214 712.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.6 CEG35602.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Coilin_N PF15862.5 CEG35603.1 - 5.2e-17 62.0 8.9 5.2e-17 62.0 8.9 3.5 2 1 1 3 3 3 1 Coilin N-terminus Malate_synthase PF01274.22 CEG35604.1 - 6.7e-111 371.1 0.0 8.9e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Questin_oxidase PF14027.6 CEG35604.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Questin oxidase-like SNF2_N PF00176.23 CEG35605.1 - 7.5e-62 209.1 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG35605.1 - 4.7e-21 75.2 0.0 6e-19 68.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEG35605.1 - 1.1e-09 37.9 0.3 2.3e-09 36.8 0.3 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CEG35605.1 - 1.2e-07 31.9 0.0 9.5e-07 29.0 0.0 2.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit PGA2 PF07543.12 CEG35605.1 - 0.33 10.9 5.1 0.93 9.5 5.1 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4218 PF13960.6 CEG35606.1 - 0.17 11.5 0.0 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Tricho_coat PF05892.11 CEG35610.1 - 0.0026 17.5 0.0 0.0026 17.5 0.0 1.0 1 0 0 1 1 1 1 Trichovirus coat protein DUF1892 PF08987.10 CEG35610.1 - 0.024 14.8 0.0 0.029 14.6 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1892) Lipase_chap PF03280.14 CEG35610.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Orai-1 PF07856.12 CEG35611.1 - 1.1e-19 70.8 8.9 1.7e-19 70.1 8.9 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity DHHC PF01529.20 CEG35612.1 - 4.7e-22 78.5 3.8 4.7e-22 78.5 3.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase C1_1 PF00130.22 CEG35612.1 - 0.026 14.4 6.1 0.065 13.1 6.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) START PF01852.19 CEG35612.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 START domain FYVE PF01363.21 CEG35614.1 - 0.023 14.9 7.4 0.043 14.0 7.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger Endonuclease_7 PF02945.15 CEG35614.1 - 0.042 13.8 4.3 0.046 13.7 2.9 1.8 1 1 1 2 2 2 0 Recombination endonuclease VII PetG PF02529.15 CEG35614.1 - 0.069 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 FUN14 PF04930.15 CEG35614.1 - 0.15 12.5 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 FUN14 family DUF2723 PF11028.8 CEG35617.1 - 1.8e-36 125.6 8.4 1.8e-36 125.6 8.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 CEG35617.1 - 1.2e-09 38.6 12.7 3.9e-09 36.9 12.7 1.9 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EB1 PF03271.17 CEG35618.1 - 0.061 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF1388 PF07142.12 CEG35618.1 - 0.14 12.1 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) GTP_EFTU PF00009.27 CEG35619.1 - 9.4e-59 198.2 0.0 2.7e-58 196.7 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CEG35619.1 - 5.8e-14 51.9 0.0 2e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CEG35619.1 - 3.4e-13 49.5 0.0 8.5e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEG35619.1 - 1.3e-07 31.9 0.0 4.2e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CEG35619.1 - 6.4e-07 29.2 0.0 2.9e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor G, domain IV Sec16 PF12932.7 CEG35620.1 - 0.11 13.1 0.2 0.22 12.1 0.2 1.5 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region MCM6_C PF18263.1 CEG35620.1 - 0.13 12.5 1.2 1.4 9.2 0.1 2.3 1 1 1 2 2 2 0 MCM6 C-terminal winged-helix domain Fib_alpha PF08702.10 CEG35620.1 - 0.79 9.9 3.4 1.4 9.1 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ovate PF04844.13 CEG35624.1 - 0.063 13.3 0.0 1.3 9.0 0.0 2.1 1 1 0 2 2 2 0 Transcriptional repressor, ovate Abhydrolase_3 PF07859.13 CEG35628.1 - 2.9e-18 66.5 0.5 4.9e-18 65.8 0.5 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CEG35628.1 - 1.6e-17 63.5 0.1 9.5e-17 61.0 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CEG35628.1 - 7.7e-09 36.5 0.5 1.2e-08 35.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CEG35628.1 - 0.0061 16.1 0.8 0.073 12.5 0.9 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 CEG35628.1 - 0.027 13.6 0.0 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 CEG35628.1 - 0.044 12.7 0.2 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Cutinase PF01083.22 CEG35628.1 - 0.055 13.4 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase Hydrolase_4 PF12146.8 CEG35628.1 - 0.055 12.7 0.5 2.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CEG35628.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase P16-Arc PF04699.14 CEG35629.1 - 3e-27 95.9 0.1 3.6e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CEG35629.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 Dip2/Utp12 Family Zn_ribbon_recom PF13408.6 CEG35630.1 - 0.033 14.7 0.8 0.052 14.1 0.8 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain HypA PF01155.19 CEG35630.1 - 0.042 13.9 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ArfGap PF01412.18 CEG35630.1 - 0.12 12.5 0.8 0.18 11.9 0.2 1.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DcpS_C PF11969.8 CEG35631.1 - 6.4e-30 104.0 0.0 1.4e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CEG35631.1 - 4.1e-07 30.8 0.0 8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal SNF2_N PF00176.23 CEG35632.1 - 8.4e-71 238.5 0.1 2.4e-70 237.0 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CEG35632.1 - 3.9e-37 126.7 0.1 3.9e-37 126.7 0.1 3.9 4 0 0 4 4 4 1 SLIDE Helicase_C PF00271.31 CEG35632.1 - 3.9e-20 72.3 0.0 1.9e-19 70.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box_2 PF09011.10 CEG35632.1 - 9.6e-18 64.6 5.6 9.6e-10 38.9 0.7 4.2 4 0 0 4 4 2 2 HMG-box domain HMG_box PF00505.19 CEG35632.1 - 2.6e-12 46.9 5.0 5.3e-09 36.4 0.9 3.3 3 0 0 3 3 2 2 HMG (high mobility group) box ResIII PF04851.15 CEG35632.1 - 6.9e-08 32.7 2.2 2.1e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG35632.1 - 8.3e-07 28.9 0.0 3.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CEG35632.1 - 2.5e-05 23.6 0.1 2.5e-05 23.6 0.1 3.0 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 CEG35632.1 - 4.4e-05 23.6 0.0 0.00066 19.8 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain HMG_box_5 PF14887.6 CEG35632.1 - 0.035 14.1 8.6 0.024 14.6 1.6 3.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Myb_DNA-bind_6 PF13921.6 CEG35632.1 - 0.054 13.7 0.0 0.31 11.3 0.0 2.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ald_Xan_dh_C2 PF02738.18 CEG35634.1 - 3.4e-189 629.9 0.0 5e-189 629.3 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CEG35634.1 - 7.4e-45 152.7 0.0 1.7e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 CEG35634.1 - 2e-28 99.0 0.0 4.8e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 CEG35634.1 - 6.6e-28 96.6 0.4 1.5e-27 95.4 0.4 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 CEG35634.1 - 1.2e-26 92.8 0.0 4.4e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 CEG35634.1 - 7.7e-08 32.2 2.0 7.7e-08 32.2 2.0 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 CEG35634.1 - 2.3 8.1 7.7 0.67 9.8 3.1 2.4 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Sep15_SelM PF08806.11 CEG35635.1 - 0.00013 22.1 0.1 0.00023 21.3 0.1 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain LisH_TPL PF17814.1 CEG35636.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 LisH-like dimerisation domain Carb_kinase PF01256.17 CEG35637.1 - 1.3e-46 159.1 0.0 1.8e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 CEG35637.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 CEG35637.1 - 0.066 12.6 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase DUF1974 PF09317.11 CEG35638.1 - 5.6e-56 190.2 0.0 1e-55 189.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 CEG35638.1 - 7e-19 68.6 0.0 1.9e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CEG35638.1 - 2.3e-10 40.9 0.1 4.2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEG35638.1 - 5.8e-09 36.0 0.0 1.8e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF501 PF04417.12 CEG35639.1 - 2.5 7.9 6.8 0.74 9.6 2.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF501) LRR_4 PF12799.7 CEG35640.1 - 4.2e-11 42.9 31.6 0.025 15.0 0.6 8.9 5 3 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG35640.1 - 2.8e-05 23.8 20.2 6.7 7.0 0.1 9.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 CEG35640.1 - 0.00065 19.9 25.4 2.2 9.2 0.1 9.2 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 CEG35640.1 - 1.2 9.0 29.8 8 6.3 1.7 8.2 5 4 1 6 6 6 0 Leucine rich repeat SlyX PF04102.12 CEG35641.1 - 0.043 14.4 12.0 0.32 11.6 1.8 2.4 2 0 0 2 2 2 0 SlyX TMEM131_like PF12371.8 CEG35641.1 - 0.089 13.1 0.7 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 131-like PDCD7 PF16021.5 CEG35641.1 - 0.097 11.8 10.7 0.15 11.2 10.7 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 RNA_pol_Rpa2_4 PF06883.12 CEG35641.1 - 0.14 12.2 0.1 0.49 10.4 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain DivIC PF04977.15 CEG35641.1 - 0.48 10.2 14.2 0.83 9.5 1.0 2.5 3 0 0 3 3 3 0 Septum formation initiator TSC22 PF01166.18 CEG35641.1 - 1.4 9.3 8.3 1 9.7 0.1 2.8 3 1 0 3 3 3 0 TSC-22/dip/bun family Csm1_N PF18504.1 CEG35641.1 - 5.4 7.4 12.5 0.75 10.2 4.1 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain FAD_binding_1 PF00667.20 CEG35646.1 - 7.6e-55 185.9 0.0 1.2e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEG35646.1 - 4.8e-35 120.8 0.2 1.5e-34 119.3 0.4 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CEG35646.1 - 8.6e-20 71.4 0.0 3.9e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEG35646.1 - 0.03 14.5 0.0 0.27 11.3 0.0 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF1428 PF07237.11 CEG35646.1 - 0.11 12.7 0.0 0.47 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Flavodoxin_5 PF12724.7 CEG35646.1 - 0.14 12.4 0.0 0.61 10.3 0.0 2.0 1 1 0 1 1 1 0 Flavodoxin domain POPLD PF08170.12 CEG35648.1 - 1.7e-16 60.3 0.0 3.9e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 CEG35648.1 - 0.0037 17.3 1.2 0.0099 15.9 0.0 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.21 CEG35648.1 - 0.0065 15.9 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain SIR2 PF02146.17 CEG35649.1 - 1.3e-56 191.4 0.0 1.9e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CEG35649.1 - 0.0012 18.6 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 CEG35649.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) UvrC_HhH_N PF08459.11 CEG35649.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NfeD PF01957.18 CEG35650.1 - 0.043 14.2 0.8 0.12 12.8 0.2 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF3945 PF13101.6 CEG35650.1 - 0.16 11.7 1.5 9.8 6.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) ArdA PF07275.11 CEG35650.1 - 3.1 8.3 6.6 2.2 8.8 0.4 2.8 2 1 0 2 2 2 0 Antirestriction protein (ArdA) LsmAD PF06741.13 CEG35650.1 - 3.9 8.1 15.8 0.13 12.8 1.3 4.0 3 1 0 3 3 3 0 LsmAD domain DUF2607 PF10795.9 CEG35652.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) DUF2909 PF11137.8 CEG35652.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) TPR_2 PF07719.17 CEG35653.1 - 1e-28 97.1 0.0 0.032 14.3 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEG35653.1 - 7.1e-22 77.8 0.0 5.3e-07 30.2 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35653.1 - 2.3e-20 71.1 0.1 0.066 13.5 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG35653.1 - 7.2e-19 66.8 1.6 0.0084 15.9 0.0 8.7 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG35653.1 - 9.2e-19 67.7 0.1 5.7e-05 23.5 0.0 6.2 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEG35653.1 - 1e-18 66.4 0.0 0.03 15.1 0.0 9.1 4 1 5 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG35653.1 - 1.6e-17 62.9 0.0 0.0013 18.4 0.0 6.8 6 2 1 7 7 6 3 TPR repeat TPR_12 PF13424.6 CEG35653.1 - 1.6e-17 63.5 0.8 0.012 15.9 0.0 6.7 3 2 3 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG35653.1 - 7.4e-16 58.2 1.1 0.00022 21.4 0.0 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CEG35653.1 - 2.1e-12 46.5 0.1 0.33 11.4 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG35653.1 - 3.5e-07 29.8 0.1 9.7 6.5 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG35653.1 - 1.1e-06 28.9 0.1 2.5 8.9 0.0 6.8 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG35653.1 - 4.9e-06 26.6 0.0 0.92 9.7 0.0 4.8 2 1 5 7 7 6 3 Tetratricopeptide repeat Rhodanese PF00581.20 CEG35653.1 - 8.1e-06 26.3 0.0 2.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain TPR_4 PF07721.14 CEG35653.1 - 3.1e-05 24.2 0.0 6.1 7.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35653.1 - 9.2e-05 22.2 3.6 0.25 11.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG35653.1 - 0.00038 19.8 0.0 0.068 12.4 0.0 3.3 1 1 2 4 4 4 2 Tetratricopeptide repeat Tryp_alpha_amyl PF00234.22 CEG35653.1 - 0.0018 18.7 1.5 0.043 14.2 1.0 2.8 2 0 0 2 2 2 1 Protease inhibitor/seed storage/LTP family HrpB1_HrpK PF09613.10 CEG35653.1 - 0.0065 16.1 0.0 0.24 11.1 0.0 3.0 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) SHNi-TPR PF10516.9 CEG35653.1 - 0.012 15.0 0.2 0.2 11.1 0.0 2.9 3 0 0 3 3 3 0 SHNi-TPR TPR_20 PF14561.6 CEG35653.1 - 0.016 15.5 1.4 1.1 9.6 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat NARP1 PF12569.8 CEG35653.1 - 0.034 13.1 0.0 0.034 13.1 0.0 3.2 3 1 0 4 4 3 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 CEG35653.1 - 0.036 14.1 0.1 44 4.1 0.0 3.8 3 1 1 4 4 3 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 CEG35653.1 - 0.047 13.8 6.4 6.7 6.8 0.0 4.9 4 1 2 6 6 4 0 MAS20 protein import receptor DUF4810 PF16068.5 CEG35653.1 - 0.064 13.8 0.1 1.6 9.3 0.0 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4810) NADH-G_4Fe-4S_3 PF10588.9 CEG35653.1 - 0.52 9.9 2.2 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region AIF-MLS PF14962.6 CEG35653.1 - 7.8 6.4 6.8 87 3.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Phostensin_N PF13916.6 CEG35654.1 - 0.0012 19.1 6.7 0.0023 18.2 0.8 2.1 1 1 1 2 2 2 2 PP1-regulatory protein, Phostensin N-terminal BACK PF07707.15 CEG35654.1 - 0.047 13.8 2.6 0.34 11.0 1.5 2.2 1 1 1 2 2 2 0 BTB And C-terminal Kelch CREPT PF16566.5 CEG35654.1 - 0.048 13.8 5.4 0.093 12.9 5.3 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Anoctamin PF04547.12 CEG35655.1 - 3.5e-79 266.8 13.7 1e-51 176.3 12.5 2.3 1 1 1 2 2 2 2 Calcium-activated chloride channel NepR PF18557.1 CEG35655.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor NepR His_Phos_2 PF00328.22 CEG35656.1 - 4e-08 33.0 0.3 1.5e-05 24.6 0.3 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA_SAD PF07973.14 CEG35658.1 - 1.2e-05 25.3 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CEG35658.1 - 0.00086 17.9 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DUF1882 PF08966.11 CEG35660.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) TFIID_20kDa PF03847.13 CEG35664.1 - 1.5e-19 70.3 0.0 3.1e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 CEG35664.1 - 0.017 15.5 1.1 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Thioredoxin PF00085.20 CEG35665.1 - 7.6e-49 164.0 0.7 4.8e-23 81.1 0.2 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CEG35665.1 - 7.8e-12 45.1 1.4 1.8e-05 24.2 0.4 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CEG35665.1 - 1.1e-09 38.5 2.0 0.0011 19.2 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CEG35665.1 - 1.4e-08 35.2 0.8 0.003 18.0 0.1 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEG35665.1 - 1e-07 32.1 0.7 0.011 15.9 0.2 2.5 2 0 0 2 2 2 2 Thioredoxin-like Phosducin PF02114.16 CEG35665.1 - 3.3e-07 29.5 0.0 0.011 14.7 0.0 2.0 1 1 0 2 2 2 2 Phosducin Redoxin PF08534.10 CEG35665.1 - 0.00014 21.6 1.7 0.012 15.3 0.1 2.6 2 1 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 CEG35665.1 - 0.00017 21.5 1.2 0.015 15.2 0.4 2.6 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 CEG35665.1 - 0.00023 20.9 0.6 0.37 10.6 0.5 2.4 2 0 0 2 2 2 2 Thioredoxin Nucleocap_ssRNA PF11128.8 CEG35665.1 - 0.012 15.3 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid Erf4 PF10256.9 CEG35665.1 - 0.068 13.3 0.0 0.87 9.7 0.0 2.5 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family PP28 PF10252.9 CEG35666.1 - 2.5e-20 72.7 25.0 2.5e-20 72.7 25.0 2.9 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 CEG35666.1 - 7.1e-09 35.2 1.3 1.4e-08 34.3 1.3 1.5 1 0 0 1 1 1 1 SAP domain Thioredoxin PF00085.20 CEG35667.1 - 1.1e-08 35.0 0.1 2.1e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CEG35667.1 - 0.00034 19.7 0.3 0.00048 19.2 0.3 1.3 1 0 0 1 1 1 1 Phosducin OmpH PF03938.14 CEG35667.1 - 0.0021 18.4 2.9 0.0045 17.3 2.9 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Herpes_UL6 PF01763.16 CEG35667.1 - 0.008 14.8 0.6 0.0097 14.5 0.6 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF3086 PF11285.8 CEG35667.1 - 0.05 12.7 0.7 0.21 10.6 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Spc7 PF08317.11 CEG35667.1 - 0.059 12.2 3.6 0.1 11.5 3.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Mating_N PF12731.7 CEG35667.1 - 0.06 13.4 0.5 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 E3_UbLigase_R4 PF13764.6 CEG35667.1 - 0.083 11.0 1.9 0.13 10.5 1.9 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Cytochrom_B562 PF07361.11 CEG35667.1 - 0.15 12.7 4.8 0.22 12.2 3.9 1.8 2 0 0 2 2 2 0 Cytochrome b562 SesA PF17107.5 CEG35667.1 - 0.27 11.4 4.3 0.61 10.3 2.3 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF465 PF04325.13 CEG35667.1 - 0.43 10.7 15.6 0.28 11.2 11.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF465) EF-1_beta_acid PF10587.9 CEG35667.1 - 1.4 9.4 10.2 0.16 12.4 4.9 2.2 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Herpes_UL14 PF03580.14 CEG35667.1 - 3.6 7.8 9.9 11 6.2 0.9 3.3 2 1 1 3 3 3 0 Herpesvirus UL14-like protein DUF4306 PF14154.6 CEG35669.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) C2 PF00168.30 CEG35670.1 - 4.3e-37 126.5 0.0 1.1e-15 57.7 0.0 3.5 3 0 0 3 3 3 3 C2 domain EF-hand_7 PF13499.6 CEG35670.1 - 2.1e-25 89.0 8.1 1.9e-11 44.2 0.5 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG35670.1 - 5.4e-24 81.9 8.1 4e-08 32.3 0.4 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 CEG35670.1 - 7.3e-17 59.8 5.0 0.00045 19.9 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CEG35670.1 - 2.2e-15 56.2 11.2 1.4e-07 31.3 0.5 4.8 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG35670.1 - 6.9e-14 50.6 5.1 0.00067 19.0 0.2 4.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CEG35670.1 - 5.7e-07 29.8 0.3 0.0022 18.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG35670.1 - 1.1e-06 28.9 0.7 0.0075 16.6 0.2 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG35670.1 - 0.0012 18.7 0.5 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CEG35670.1 - 0.019 15.1 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF3418 PF11898.8 CEG35671.1 - 0.028 13.1 0.4 0.032 12.9 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) TEX19 PF15553.6 CEG35674.1 - 0.2 11.6 7.9 5.6 6.9 0.0 3.5 3 0 0 3 3 3 0 Testis-expressed protein 19 gag_pre-integrs PF13976.6 CEG35678.1 - 0.025 14.4 0.2 0.042 13.7 0.2 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain rve PF00665.26 CEG35678.1 - 0.079 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.14 CEG35679.1 - 0.00086 19.0 0.5 0.0012 18.5 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane PF01061.24 CEG35680.1 - 2.1e-65 220.1 72.5 4.6e-36 124.2 27.9 3.1 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CEG35680.1 - 3e-35 121.7 0.0 3e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG35680.1 - 9.1e-09 35.5 0.0 0.079 12.7 0.0 3.7 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 CEG35680.1 - 6e-08 32.5 0.1 6e-08 32.5 0.1 3.4 3 0 0 3 3 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 CEG35680.1 - 4.4e-07 30.0 0.2 0.0066 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CEG35680.1 - 6e-07 30.0 0.0 0.007 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEG35680.1 - 2.7e-05 23.8 6.0 0.019 14.7 1.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CEG35680.1 - 4.2e-05 23.2 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEG35680.1 - 4.8e-05 23.6 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEG35680.1 - 0.00033 20.4 0.1 1 9.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 CEG35680.1 - 0.00034 20.1 1.4 0.46 9.9 0.1 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CEG35680.1 - 0.00056 19.2 0.9 0.055 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 CEG35680.1 - 0.00081 19.8 0.4 4.7 7.6 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG35680.1 - 0.0011 19.6 0.0 0.47 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEG35680.1 - 0.0036 17.4 0.8 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 CEG35680.1 - 0.0042 17.0 0.8 4.2 7.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain cobW PF02492.19 CEG35680.1 - 0.0072 15.9 0.2 0.72 9.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CEG35680.1 - 0.013 16.1 3.8 0.83 10.1 0.7 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CEG35680.1 - 0.026 14.5 0.1 1.8 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CEG35680.1 - 0.032 14.4 0.2 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CEG35680.1 - 0.033 14.3 0.1 13 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEG35680.1 - 0.036 14.5 0.2 7.8 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 CEG35680.1 - 0.045 13.7 0.2 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 CEG35680.1 - 0.05 13.7 3.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RuvB_N PF05496.12 CEG35680.1 - 0.089 12.5 0.3 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Baculo_11_kDa PF06143.11 CEG35680.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 1 0 Baculovirus 11 kDa family AAA_24 PF13479.6 CEG35680.1 - 0.12 12.1 0.3 11 5.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG35680.1 - 0.2 11.6 0.2 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CEG35680.1 - 0.24 11.7 1.9 27 5.0 1.1 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 CEG35680.1 - 0.48 9.5 59.0 0.033 13.3 18.3 3.8 2 2 0 2 2 1 0 ABC-2 family transporter protein Pkinase PF00069.25 CEG35681.1 - 6.2e-32 111.0 0.0 8.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG35681.1 - 1.4e-10 40.9 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Bmt2 PF11968.8 CEG35688.1 - 4.8e-12 46.2 0.3 5.4e-11 42.8 0.0 2.0 1 1 1 2 2 2 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Es2 PF09751.9 CEG35689.1 - 4.3e-45 155.2 15.3 1.3e-41 143.8 15.2 3.3 1 1 0 1 1 1 1 Nuclear protein Es2 Pyr_redox_2 PF07992.14 CEG35690.1 - 6.1e-10 38.8 0.1 2.3e-08 33.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEG35690.1 - 0.00016 20.9 0.1 0.00045 19.5 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CEG35690.1 - 0.0012 18.2 0.4 0.52 9.5 0.2 3.1 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase IBR PF01485.21 CEG35691.1 - 5.3e-14 52.2 50.0 1.2e-07 31.8 16.0 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain ATP-synt_Eps PF04627.13 CEG35692.1 - 9.7e-18 63.9 0.6 1.3e-17 63.5 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Wyosine_form PF08608.12 CEG35693.1 - 2.2e-26 91.9 0.0 5.3e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 CEG35693.1 - 7.1e-24 84.6 0.3 2.4e-23 82.9 0.1 2.0 2 0 0 2 2 2 1 Flavodoxin Radical_SAM PF04055.21 CEG35693.1 - 9.7e-23 81.4 0.1 1.8e-22 80.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF4464 PF14713.6 CEG35693.1 - 0.12 12.0 1.9 0.18 11.3 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Microtub_bind PF13931.6 CEG35693.1 - 0.26 11.6 2.4 0.45 10.9 1.7 1.8 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding WBS_methylT PF12589.8 CEG35693.1 - 1.1 10.0 7.0 0.21 12.3 2.5 2.1 1 1 1 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Moulting_cycle PF04870.16 CEG35693.1 - 1.2 8.4 7.8 1.9 7.7 7.8 1.2 1 0 0 1 1 1 0 Moulting cycle NDK PF00334.19 CEG35694.1 - 3.1e-34 117.9 0.0 2.6e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CEG35694.1 - 0.0061 16.4 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 DUF1126 PH-like domain Yop-YscD_ppl PF16693.5 CEG35695.1 - 0.029 13.8 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain PAN_1 PF00024.26 CEG35696.1 - 1.1e-10 41.3 0.4 2.2e-10 40.3 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 CEG35696.1 - 2.4e-08 33.8 1.7 2.4e-08 33.8 1.7 2.6 2 1 0 2 2 2 1 PAN domain PAN_2 PF08276.11 CEG35696.1 - 0.0055 16.8 1.8 0.0055 16.8 1.8 2.2 2 0 0 2 2 2 1 PAN-like domain Trp_oprn_chp PF09534.10 CEG35698.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) WBP-1 PF11669.8 CEG35698.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 Pkinase PF00069.25 CEG35699.1 - 1.4e-65 221.3 0.0 2.5e-65 220.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.22 CEG35699.1 - 7.7e-48 162.1 0.9 1.2e-38 132.3 0.1 2.4 1 1 1 2 2 2 2 Ras family Pkinase_Tyr PF07714.17 CEG35699.1 - 1.4e-34 119.6 0.0 3.9e-34 118.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Roc PF08477.13 CEG35699.1 - 2.4e-29 102.0 0.3 1e-28 99.9 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG35699.1 - 9.2e-13 48.0 0.1 1.8e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Kinase-like PF14531.6 CEG35699.1 - 7.6e-07 28.7 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CEG35699.1 - 3.3e-05 22.8 0.0 6.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Gtr1_RagA PF04670.12 CEG35699.1 - 8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region APH PF01636.23 CEG35699.1 - 0.0022 18.0 0.7 0.0063 16.5 0.7 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family SRPRB PF09439.10 CEG35699.1 - 0.004 16.6 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEG35699.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Kdo PF06293.14 CEG35699.1 - 0.0058 16.0 0.2 0.011 15.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 CEG35699.1 - 0.024 15.2 0.0 0.095 13.2 0.0 2.0 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase MMR_HSR1 PF01926.23 CEG35699.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EAP30 PF04157.16 CEG35700.1 - 5.4e-39 133.9 0.1 7.9e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CEG35700.1 - 2.4e-16 59.7 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 CEG35700.1 - 0.0087 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DCX PF03607.17 CEG35701.1 - 0.051 13.7 0.2 0.19 11.8 0.1 2.0 2 1 0 2 2 2 0 Doublecortin SirA PF10747.9 CEG35701.1 - 0.13 12.6 0.1 0.16 12.3 0.1 1.1 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Glyco_transf_90 PF05686.12 CEG35702.1 - 1.2e-18 67.2 7.4 5.9e-18 65.0 1.6 3.5 2 2 0 2 2 2 2 Glycosyl transferase family 90 SpoIIE PF07228.12 CEG35703.1 - 1.2e-09 38.3 0.0 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CEG35703.1 - 1.8e-08 34.3 0.1 3.8e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C RVT_2 PF07727.14 CEG35704.1 - 0.048 13.3 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PIN_11 PF18479.1 CEG35706.1 - 0.1 12.8 0.0 1.9 8.7 0.0 2.0 1 1 0 2 2 2 0 PIN like domain zinc_ribbon_13 PF09855.9 CEG35706.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) IQ PF00612.27 CEG35707.1 - 1.5e-09 36.8 80.1 0.0043 16.7 0.9 13.0 13 0 0 13 13 13 8 IQ calmodulin-binding motif LRR_6 PF13516.6 CEG35707.1 - 1.9e-07 30.6 27.5 8.9 6.7 0.1 11.8 13 0 0 13 13 13 3 Leucine Rich repeat LRR_1 PF00560.33 CEG35707.1 - 3.1e-06 27.0 13.3 2.4 9.0 0.1 9.6 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_4 PF12799.7 CEG35707.1 - 1.8e-05 25.0 18.3 1.7 9.2 0.0 8.5 8 2 1 10 10 10 2 Leucine Rich repeats (2 copies) DUF3598 PF12204.8 CEG35707.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) EF-hand_7 PF13499.6 CEG35709.1 - 1.9e-28 98.7 18.6 4.2e-08 33.5 0.1 9.7 9 1 0 9 9 9 4 EF-hand domain pair EF-hand_1 PF00036.32 CEG35709.1 - 2.2e-22 76.9 18.3 0.00019 20.7 0.1 10.9 11 0 0 11 11 11 5 EF hand EF-hand_8 PF13833.6 CEG35709.1 - 1.3e-19 69.7 12.6 2.4e-05 24.1 0.2 8.3 8 1 1 9 9 9 4 EF-hand domain pair EF-hand_6 PF13405.6 CEG35709.1 - 1.1e-15 56.2 20.4 0.014 15.3 0.0 10.6 10 0 0 10 10 10 4 EF-hand domain EF-hand_9 PF14658.6 CEG35709.1 - 3.8e-09 36.7 0.9 0.011 16.1 0.0 6.7 6 0 0 6 6 6 1 EF-hand domain EF-hand_5 PF13202.6 CEG35709.1 - 1.5e-07 30.6 9.0 0.091 12.3 0.1 6.7 7 0 0 7 7 7 3 EF hand EF-hand_11 PF08976.11 CEG35709.1 - 0.00082 20.2 3.2 0.067 14.1 0.1 5.3 7 0 0 7 7 7 1 EF-hand domain EF-hand_4 PF12763.7 CEG35709.1 - 0.0045 16.9 3.9 0.41 10.6 0.0 5.0 5 0 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CEG35709.1 - 0.013 15.7 0.1 0.084 13.1 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Choline_transpo PF04515.12 CEG35710.1 - 2.7e-51 174.7 18.2 2.7e-51 174.7 18.2 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF3285 PF11688.8 CEG35710.1 - 3.6 7.6 5.5 1.3 9.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Chromo PF00385.24 CEG35712.1 - 2e-09 37.2 0.4 3.8e-09 36.3 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BNR_3 PF13859.6 CEG35712.1 - 0.024 13.9 0.0 0.027 13.8 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain Mtf2_C PF14061.6 CEG35712.1 - 0.046 13.9 0.1 0.072 13.3 0.1 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 OSCP PF00213.18 CEG35716.1 - 1.3e-45 155.7 1.8 1.5e-45 155.4 1.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Ras PF00071.22 CEG35717.1 - 2.6e-47 160.4 0.0 3.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG35717.1 - 7e-36 123.1 0.0 1.3e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG35717.1 - 1.2e-14 54.2 0.0 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEG35717.1 - 1.4e-05 24.7 0.3 0.0029 17.1 0.3 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEG35717.1 - 3.9e-05 23.6 0.0 0.0078 16.1 0.0 2.8 1 1 2 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 CEG35717.1 - 6.9e-05 22.3 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG35717.1 - 0.0003 20.3 0.0 0.00049 19.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG35717.1 - 0.00045 20.3 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PGP_phosphatase PF09419.10 CEG35717.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase PduV-EutP PF10662.9 CEG35717.1 - 0.05 13.3 0.0 5.8 6.7 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tfb2_C PF18307.1 CEG35717.1 - 0.088 13.3 0.0 4.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain AAA_15 PF13175.6 CEG35717.1 - 0.091 12.4 0.0 4.4 6.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 CEG35717.1 - 0.096 12.1 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein zf-RING_2 PF13639.6 CEG35718.1 - 1.6e-05 25.2 3.7 1.6e-05 25.2 3.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG35718.1 - 3.2e-05 24.1 1.4 3.2e-05 24.1 1.4 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG35718.1 - 8.1e-05 22.4 4.6 8.1e-05 22.4 4.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG35718.1 - 0.00026 20.9 3.0 0.00026 20.9 3.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain PX PF00787.24 CEG35718.1 - 0.0014 18.6 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 PX domain zf-C3HC4 PF00097.25 CEG35718.1 - 0.0023 17.8 3.8 0.0023 17.8 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG35718.1 - 0.0036 17.0 1.1 0.0036 17.0 1.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger Zn-ribbon_8 PF09723.10 CEG35718.1 - 0.031 14.4 0.8 0.031 14.4 0.8 2.2 2 1 0 2 2 2 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 CEG35718.1 - 0.042 13.9 1.8 0.12 12.5 1.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG35718.1 - 0.049 13.5 2.5 0.12 12.3 2.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEG35718.1 - 0.053 13.4 2.1 0.14 12.1 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CEG35718.1 - 0.087 12.7 4.1 0.26 11.2 4.1 1.9 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 CEG35718.1 - 0.73 9.9 3.9 0.42 10.7 1.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CEG35718.1 - 7.8 6.6 11.5 0.33 11.0 4.7 2.3 2 0 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 CEG35719.1 - 0.0097 16.2 3.3 0.049 13.9 2.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG35719.1 - 0.011 16.0 0.5 0.011 16.0 0.5 3.3 4 0 0 4 4 4 0 Ring finger domain PX PF00787.24 CEG35719.1 - 0.031 14.3 0.2 0.074 13.0 0.2 1.6 1 0 0 1 1 1 0 PX domain Glyco_trans_2_3 PF13632.6 CEG35720.1 - 7.8e-18 65.1 0.0 7.8e-18 65.1 0.0 3.3 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 CEG35720.1 - 1.6e-12 46.8 3.7 1e-07 30.9 0.1 2.7 3 1 1 4 4 4 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 CEG35720.1 - 1e-08 35.4 0.0 2.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 PH PF00169.29 CEG35720.1 - 1.1e-08 35.5 0.1 2.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Glycos_transf_2 PF00535.26 CEG35720.1 - 2.7e-07 30.5 0.0 0.027 14.3 0.0 3.3 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEG35720.1 - 1.8e-05 24.3 0.0 0.0015 18.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_8 PF15409.6 CEG35720.1 - 0.0055 17.0 0.4 0.045 14.0 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 CEG35720.1 - 0.0055 17.0 9.0 0.0055 17.0 9.0 2.1 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 CEG35720.1 - 0.0077 16.6 1.1 0.017 15.6 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_trans_2_3 PF13632.6 CEG35721.1 - 2.2e-14 53.8 3.9 3.5e-14 53.2 0.0 2.9 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 CEG35721.1 - 1.8e-09 36.7 1.7 1.2e-05 24.0 0.0 2.9 2 1 1 3 3 3 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 CEG35721.1 - 3.5e-09 36.9 0.0 0.00011 22.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 PH PF00169.29 CEG35721.1 - 3.6e-09 37.1 0.2 1.8e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 PH domain Glycos_transf_2 PF00535.26 CEG35721.1 - 1.7e-08 34.4 0.0 0.0034 17.2 0.0 3.4 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEG35721.1 - 1.1e-05 25.0 0.0 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_11 PF15413.6 CEG35721.1 - 0.002 18.5 0.3 0.0063 16.9 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG35721.1 - 0.0047 17.2 2.6 0.027 14.7 0.4 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain zf-C6H2 PF15801.5 CEG35721.1 - 0.012 15.9 11.3 0.012 15.9 11.3 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Peptidase_A24 PF01478.18 CEG35721.1 - 0.33 11.4 3.0 5.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Type IV leader peptidase family DUF2873 PF11395.8 CEG35721.1 - 0.69 9.8 4.4 1.9 8.4 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Peptidase_C39 PF03412.15 CEG35722.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase C39 family Anthrax_toxA PF03497.16 CEG35724.1 - 0.069 13.3 0.0 0.078 13.1 0.0 1.0 1 0 0 1 1 1 0 Anthrax toxin LF subunit DUF423 PF04241.15 CEG35726.1 - 1.1e-28 99.2 1.6 1.5e-28 98.8 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) EGF_2 PF07974.13 CEG35727.1 - 1.3e-13 51.0 66.6 1.8e-05 25.0 9.9 5.8 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.24 CEG35727.1 - 1.9 8.7 59.5 0.31 11.2 9.0 4.8 4 1 1 5 5 5 0 Laminin EGF domain EGF PF00008.27 CEG35727.1 - 4.6 7.6 45.5 1.2 9.5 5.5 5.8 5 0 0 5 5 5 0 EGF-like domain Rad51 PF08423.11 CEG35728.1 - 4.1e-37 127.8 0.1 8.6e-37 126.8 0.0 1.5 2 0 0 2 2 2 1 Rad51 ATPase PF06745.13 CEG35728.1 - 5.1e-08 32.5 0.1 2e-07 30.6 0.1 1.9 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CEG35728.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CEG35728.1 - 2.7e-06 26.9 0.0 0.0058 16.0 0.0 2.5 2 1 1 3 3 3 2 DnaB-like helicase C terminal domain RecA PF00154.21 CEG35728.1 - 0.00014 21.5 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 CEG35728.1 - 0.042 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEG35728.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG35728.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CEG35729.1 - 4.3e-09 35.6 0.0 6.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ASH PF15780.5 CEG35731.1 - 1.6e-16 60.3 15.2 0.036 14.3 0.1 12.0 14 1 1 15 15 15 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Transglut_C PF00927.22 CEG35731.1 - 0.03 14.4 0.0 0.84 9.8 0.0 2.7 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain PapD-like PF14874.6 CEG35731.1 - 0.047 13.9 6.7 0.058 13.5 0.2 4.1 5 0 0 5 5 5 0 Flagellar-associated PapD-like 6PF2K PF01591.18 CEG35732.1 - 1.4e-64 217.4 0.0 2e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEG35732.1 - 6.4e-23 81.5 0.0 2.4e-22 79.6 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEG35732.1 - 6.1e-10 39.4 0.1 9.8e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEG35732.1 - 0.00028 20.4 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CEG35732.1 - 0.042 14.3 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S7 PF00177.21 CEG35734.1 - 3.2e-36 124.2 2.3 3.9e-36 123.9 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L6e PF01159.19 CEG35734.1 - 0.053 14.0 0.3 0.12 12.9 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L6e Kinesin PF00225.23 CEG35735.1 - 1.6e-101 339.6 1.4 1.6e-101 339.6 1.4 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG35735.1 - 1.8e-46 157.7 6.1 2e-46 157.6 0.1 3.6 2 0 0 2 2 2 1 Microtubule binding MFS_1 PF07690.16 CEG35735.1 - 2.6e-17 62.8 12.4 5.4e-12 45.3 4.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_helicase PF00910.22 CEG35735.1 - 0.01 16.2 0.2 0.74 10.2 0.1 3.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 CEG35735.1 - 0.45 10.8 3.4 17 5.7 0.0 4.0 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 CEG35736.1 - 0.11 11.8 5.2 0.14 11.5 5.2 1.1 1 0 0 1 1 1 0 KaiC U3_snoRNA_assoc PF08297.11 CEG35736.1 - 0.43 11.3 16.5 0.11 13.2 1.4 2.3 2 0 0 2 2 2 0 U3 snoRNA associated Methyltransf_25 PF13649.6 CEG35737.1 - 3.9e-09 37.1 0.0 5.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG35737.1 - 3e-08 33.3 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CEG35737.1 - 3.9e-07 30.0 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG35737.1 - 2.2e-06 27.3 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CEG35737.1 - 4.4e-06 26.7 0.1 7.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG35737.1 - 5.7e-06 26.3 0.1 0.00013 21.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEG35737.1 - 2.5e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 CEG35737.1 - 2.7e-05 24.7 0.0 4.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CEG35737.1 - 0.00035 20.2 0.0 0.0011 18.5 0.0 1.7 1 1 1 2 2 2 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 CEG35737.1 - 0.00048 20.8 0.1 0.0008 20.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain ADP_PFK_GK PF04587.15 CEG35737.1 - 0.00089 17.9 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region TrmK PF04816.12 CEG35737.1 - 0.0063 16.1 0.1 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase PCMT PF01135.19 CEG35737.1 - 0.0068 16.2 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CEG35737.1 - 0.021 14.4 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 CEG35737.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 CEG35737.1 - 0.072 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 CEG35737.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEG35737.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PEX11 PF05648.14 CEG35739.1 - 1.6e-38 132.4 2.8 1.8e-38 132.2 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) VPS11_C PF12451.8 CEG35739.1 - 0.094 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal TRAP-gamma PF07074.12 CEG35740.1 - 0.28 10.7 0.8 0.44 10.1 0.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) HTH_Tnp_Tc3_2 PF01498.18 CEG35741.1 - 0.0088 16.3 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Transposase RNase_H PF00075.24 CEG35742.1 - 2.9e-27 95.6 0.5 2.9e-27 95.6 0.5 1.6 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 CEG35742.1 - 1.5e-19 70.0 6.9 1.2e-17 63.9 2.7 2.8 2 0 0 2 2 2 2 Caulimovirus viroplasmin tRNA_Me_trans PF03054.16 CEG35743.1 - 1e-112 376.5 0.0 2.3e-106 355.6 0.0 2.0 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 CEG35743.1 - 3e-07 29.8 0.0 1.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 CEG35743.1 - 1.3e-05 24.9 0.0 9.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CEG35743.1 - 0.0014 18.1 0.3 0.0077 15.8 0.2 2.3 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 CEG35743.1 - 0.0018 18.1 0.2 0.0095 15.7 0.2 2.2 1 1 0 1 1 1 1 PP-loop family DUF1479 PF07350.12 CEG35744.1 - 6.1e-07 28.6 0.0 0.00059 18.7 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 CEG35744.1 - 1.8e-06 28.4 0.0 3.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Lipid_bd PF12888.7 CEG35745.1 - 0.085 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipid-binding putative hydrolase AFG1_ATPase PF03969.16 CEG35746.1 - 1.8e-100 336.4 0.2 2.2e-100 336.1 0.2 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 CEG35746.1 - 0.0015 18.9 0.4 0.21 11.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG35746.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEG35746.1 - 0.029 14.7 0.3 14 6.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.18 CEG35746.1 - 0.072 12.9 0.4 0.66 9.8 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein Glyco_trans_1_2 PF13524.6 CEG35747.1 - 2.4 8.6 15.5 7.4 7.0 1.4 3.6 1 1 2 3 3 3 0 Glycosyl transferases group 1 ApbA_C PF08546.11 CEG35750.1 - 7.8e-31 106.9 0.2 1.3e-30 106.2 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CEG35750.1 - 1.3e-13 50.9 0.0 2.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 CEG35750.1 - 0.078 13.6 3.4 0.3 11.7 0.0 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_C2 PF00648.21 CEG35751.1 - 1.8e-46 158.5 0.0 5.8e-46 156.9 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CEG35751.1 - 5.6e-21 75.3 1.3 1.1e-08 35.4 0.1 4.7 4 1 0 4 4 4 3 Calpain large subunit, domain III Myb_DNA-binding PF00249.31 CEG35752.1 - 1.2e-30 105.5 1.7 1.5e-15 57.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG35752.1 - 1.8e-20 72.9 0.9 6.1e-15 55.2 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG35752.1 - 1.1e-06 28.5 0.1 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 CEG35752.1 - 0.047 13.7 0.0 0.26 11.3 0.0 2.1 1 1 1 2 2 2 0 SLIDE SAPS PF04499.15 CEG35756.1 - 0.002 17.0 0.0 0.0056 15.5 0.0 1.8 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Hexapep PF00132.24 CEG35757.1 - 3.9e-20 70.8 26.4 3.3e-07 29.8 0.4 5.8 3 2 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 CEG35757.1 - 8.5e-13 48.6 0.0 2.5e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 WD40 PF00400.32 CEG35757.1 - 3.2e-11 43.6 2.3 0.011 16.6 0.0 6.6 5 1 0 5 5 5 2 WD domain, G-beta repeat WW PF00397.26 CEG35757.1 - 9.1e-06 25.7 0.3 2.4e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 WW domain EF-hand_7 PF13499.6 CEG35757.1 - 0.00085 19.7 0.4 0.25 11.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CEG35757.1 - 0.0017 18.2 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG35757.1 - 0.025 14.5 0.2 0.33 11.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CEG35757.1 - 0.12 12.0 0.4 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 EF hand Kinesin PF00225.23 CEG35758.1 - 1.3e-89 300.4 0.6 2e-89 299.8 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG35758.1 - 6.5e-19 68.3 0.1 1.4e-17 64.0 0.1 2.4 1 1 0 1 1 1 1 Microtubule binding Guanylate_cyc PF00211.20 CEG35758.1 - 3.3e-08 33.4 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4618 PF15397.6 CEG35758.1 - 0.0019 17.7 0.3 0.0019 17.7 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) VMR2 PF17055.5 CEG35758.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Viral matrix protein M2 Telomerase_RBD PF12009.8 CEG35759.1 - 1.3e-27 96.5 2.3 1.3e-27 96.5 2.3 2.2 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CEG35759.1 - 6.3e-16 58.6 0.1 2e-12 47.1 0.1 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) FYVE PF01363.21 CEG35763.1 - 6.6e-09 35.8 9.0 6.6e-09 35.8 9.0 2.7 2 0 0 2 2 2 1 FYVE zinc finger Rad50_zn_hook PF04423.14 CEG35763.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif C1_2 PF03107.16 CEG35763.1 - 0.42 11.0 11.5 0.21 11.9 7.7 2.5 2 0 0 2 2 2 0 C1 domain TniQ PF06527.11 CEG35763.1 - 0.62 10.8 6.9 1.2 9.8 6.9 1.5 1 0 0 1 1 1 0 TniQ FYVE_2 PF02318.16 CEG35763.1 - 1.4 9.1 11.4 0.32 11.2 7.6 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger RXLR_WY PF18634.1 CEG35764.1 - 1.8e-09 37.4 0.1 0.023 14.6 0.0 4.0 3 0 0 3 3 3 3 RXLR phytopathogen effector protein WY-domain HrcA PF01628.21 CEG35764.1 - 0.1 12.5 0.2 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 HrcA protein C terminal domain T3RM_EcoP15I_C PF18273.1 CEG35764.1 - 1.4 9.2 3.7 1.4 9.3 0.3 2.5 3 0 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain Reprolysin_5 PF13688.6 CEG35765.1 - 0.022 14.9 0.6 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CEG35765.1 - 0.03 14.8 0.2 0.79 10.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like RXLR_WY PF18634.1 CEG35767.1 - 6.2e-05 22.9 0.4 0.78 9.7 0.0 3.9 4 0 0 4 4 4 2 RXLR phytopathogen effector protein WY-domain Peptidase_S74 PF13884.6 CEG35768.1 - 7.3e-06 26.2 0.0 5.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Chaperone of endosialidase Vps51 PF08700.11 CEG35769.1 - 1.5e-23 82.6 0.8 6.7e-23 80.6 0.8 2.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 CEG35769.1 - 5.7e-14 51.5 11.4 1.2e-13 50.5 11.4 1.4 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 CEG35769.1 - 6.1e-13 49.0 3.4 1.8e-12 47.4 3.4 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps54_N PF10475.9 CEG35769.1 - 1.5e-07 31.0 4.4 5.4e-07 29.2 4.4 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CEG35769.1 - 1.3e-05 25.2 0.8 7e-05 22.9 0.8 2.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CEG35769.1 - 0.0002 21.5 2.4 0.00034 20.8 0.2 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 BORCS6 PF10157.9 CEG35769.1 - 0.00021 21.5 0.3 0.00065 20.0 0.3 1.9 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 LIF_OSM PF01291.17 CEG35769.1 - 0.0038 17.4 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 LIF / OSM family MIF4G_like_2 PF09090.11 CEG35769.1 - 0.016 14.7 0.1 0.1 12.1 0.0 2.4 3 0 0 3 3 3 0 MIF4G like DUF1198 PF06711.11 CEG35769.1 - 0.2 11.7 2.5 0.82 9.7 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1198) HIP1_clath_bdg PF16515.5 CEG35769.1 - 0.63 10.7 3.8 0.4 11.3 0.1 2.7 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CRT-like PF08627.10 CEG35770.1 - 1.9e-59 201.3 12.8 2.2e-59 201.1 12.8 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 CEG35770.1 - 9.9e-08 31.8 0.4 9.9e-08 31.8 0.4 2.2 2 0 0 2 2 2 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 CEG35770.1 - 0.00011 21.5 3.1 0.00035 19.8 1.2 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter peroxidase PF00141.23 CEG35772.1 - 1.3e-45 155.8 0.0 2.6e-45 154.9 0.0 1.4 1 1 0 1 1 1 1 Peroxidase baeRF_family6 PF18848.1 CEG35775.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 RSN1_7TM PF02714.15 CEG35776.1 - 2.8e-55 187.6 19.0 2.8e-55 187.6 19.0 2.2 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEG35776.1 - 7.4e-28 97.3 0.5 7.4e-28 97.3 0.5 3.5 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEG35776.1 - 7.4e-25 88.2 1.2 1.8e-15 57.6 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF5081 PF16887.5 CEG35777.1 - 0.085 11.9 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) Amidase PF01425.21 CEG35778.1 - 5e-88 296.0 0.1 1.5e-87 294.4 0.1 1.6 1 1 0 1 1 1 1 Amidase Put_DNA-bind_N PF06971.13 CEG35778.1 - 0.61 10.2 2.4 1.8 8.6 0.1 2.9 2 1 1 3 3 3 0 Putative DNA-binding protein N-terminus 7TM_GPCR_Srd PF10317.9 CEG35779.1 - 0.089 12.0 0.1 0.09 11.9 0.1 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Peptidase_C2 PF00648.21 CEG35780.1 - 1.4e-57 195.0 0.6 4.6e-54 183.4 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Toxin_29 PF08116.11 CEG35780.1 - 0.046 13.7 2.2 8.8 6.4 0.1 3.4 3 0 0 3 3 3 0 PhTx neurotoxin family AA_permease_2 PF13520.6 CEG35783.1 - 7.4e-37 127.2 37.3 7.4e-37 127.2 37.3 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 CEG35783.1 - 4.4e-26 91.5 38.7 2.2e-25 89.2 38.3 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 CEG35783.1 - 2.1e-12 46.9 6.9 2.1e-12 46.9 6.9 3.5 3 0 0 3 3 3 1 C-terminus of AA_permease DUF1270 PF06900.11 CEG35783.1 - 0.081 13.3 0.7 0.081 13.3 0.7 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1270) ELFV_dehydrog PF00208.21 CEG35785.1 - 4.4e-35 121.6 0.0 7.8e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEG35785.1 - 1.6e-22 79.0 3.5 2.1e-19 68.7 0.8 3.4 3 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CEG35785.1 - 0.052 13.4 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TSC22 PF01166.18 CEG35786.1 - 0.096 13.0 0.2 0.096 13.0 0.2 6.1 5 1 1 6 6 6 0 TSC-22/dip/bun family Rnk_N PF14760.6 CEG35786.1 - 0.61 10.6 14.4 0.8 10.2 0.3 4.9 4 1 0 4 4 4 0 Rnk N-terminus DUF1682 PF07946.14 CEG35787.1 - 8.5e-64 215.8 0.2 1e-63 215.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CLTH PF10607.9 CEG35788.1 - 2e-27 95.9 1.9 1.4e-26 93.2 0.0 2.4 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain MnmE_helical PF12631.7 CEG35788.1 - 0.021 15.0 4.8 0.034 14.3 4.8 1.2 1 0 0 1 1 1 0 MnmE helical domain EH_Signature PF15611.6 CEG35788.1 - 0.077 12.4 1.2 0.15 11.5 1.2 1.6 1 1 0 1 1 1 0 EH_Signature domain DUF572 PF04502.13 CEG35788.1 - 0.23 11.1 4.1 0.19 11.3 1.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) C12orf66_like PF09404.10 CEG35789.1 - 4.2e-35 121.4 6.0 1.3e-14 54.0 0.0 4.3 3 1 0 4 4 4 4 KICSTOR complex C12orf66 like DNA_pol_B_2 PF03175.13 CEG35790.1 - 5.3e-28 98.1 18.6 1e-24 87.3 5.2 2.8 2 1 1 3 3 3 2 DNA polymerase type B, organellar and viral Pepsin-I3 PF06394.13 CEG35791.1 - 0.076 13.2 1.2 0.23 11.7 1.2 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain FANCI_S1 PF14675.6 CEG35792.1 - 0.012 15.1 0.3 0.041 13.4 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 Suf PF05843.14 CEG35793.1 - 1e-46 160.3 22.5 5e-46 158.0 10.8 5.2 3 2 3 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEG35793.1 - 2.5e-08 34.1 5.6 6.2e-05 23.5 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CEG35793.1 - 4.9e-06 25.9 5.7 0.03 13.4 0.0 4.7 3 2 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 CEG35793.1 - 3e-05 24.4 0.0 0.087 13.3 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35793.1 - 0.0082 16.3 0.0 0.23 11.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG35793.1 - 0.064 13.9 11.1 1.4 9.6 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2368 PF10166.9 CEG35793.1 - 0.59 9.7 4.9 1.2 8.7 4.9 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Androgen_recep PF02166.16 CEG35793.1 - 4.2 6.1 7.5 6.9 5.4 7.5 1.2 1 0 0 1 1 1 0 Androgen receptor TPR_2 PF07719.17 CEG35793.1 - 9.1 6.7 8.5 6.5 7.1 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PspB PF06667.12 CEG35794.1 - 0.011 15.7 0.9 0.036 14.1 0.9 1.8 1 0 0 1 1 1 0 Phage shock protein B CENP-Q PF13094.6 CEG35794.1 - 0.76 10.0 8.6 0.95 9.6 2.0 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GOLD_2 PF13897.6 CEG35795.1 - 3.6e-05 24.3 0.4 0.042 14.4 0.0 2.8 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking F-box-like PF12937.7 CEG35795.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF16 PF01519.16 CEG35795.1 - 0.69 10.4 5.0 0.38 11.3 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 S8_pro-domain PF16470.5 CEG35795.1 - 4.6 8.1 7.9 0.19 12.5 1.3 2.1 2 0 0 2 2 2 0 Peptidase S8 pro-domain Csm1_N PF18504.1 CEG35795.1 - 5.5 7.4 7.1 0.61 10.5 0.9 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF5352 PF17303.2 CEG35801.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) PX PF00787.24 CEG35802.1 - 2e-08 34.2 0.1 4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 PX domain Tubulin PF00091.25 CEG35803.1 - 1.4e-39 136.3 0.9 2.1e-39 135.8 0.9 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 CEG35803.1 - 1.6e-33 114.9 1.1 1.6e-33 114.9 1.1 2.6 2 1 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 CEG35803.1 - 2.7 7.1 7.6 12 4.9 1.9 2.7 1 1 1 2 2 2 0 Tubulin like ArAE_1_C PF11728.8 CEG35804.1 - 0.093 12.7 0.8 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain SSXT PF05030.12 CEG35805.1 - 3.8e-06 26.4 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 SSXT protein (N-terminal region) ATP-synt_ab PF00006.25 CEG35806.1 - 8.1e-68 228.3 0.0 1.2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEG35806.1 - 1.6e-11 44.5 0.2 3.7e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Exonuc_VII_L PF02601.15 CEG35807.1 - 0.29 10.7 9.9 0.36 10.4 9.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MRP-S26 PF14943.6 CEG35807.1 - 1.7 8.5 20.1 2.7 7.9 20.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Neur_chan_memb PF02932.16 CEG35807.1 - 3.3 7.7 4.8 5.5 7.0 4.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DnaJ PF00226.31 CEG35808.1 - 6e-19 67.9 0.1 1.3e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF92 PF01940.16 CEG35809.1 - 3.7e-72 242.6 4.6 4.6e-72 242.2 4.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF3429 PF11911.8 CEG35809.1 - 0.67 10.2 7.3 1.1 9.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DUF4939 PF16297.5 CEG35811.1 - 0.044 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) C2 PF00168.30 CEG35812.1 - 2.2e-14 53.6 0.0 5.2e-06 26.7 0.0 2.9 3 0 0 3 3 3 2 C2 domain C1_1 PF00130.22 CEG35812.1 - 8e-07 28.8 6.3 8e-07 28.8 6.3 2.9 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEG35812.1 - 0.00015 22.0 2.5 0.0015 18.8 1.3 2.7 2 0 0 2 2 2 1 C1 domain Reticulon PF02453.17 CEG35812.1 - 0.0024 17.9 5.4 0.0082 16.1 0.1 2.4 2 0 0 2 2 2 1 Reticulon Pex24p PF06398.11 CEG35812.1 - 0.0032 16.5 0.1 0.66 8.9 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Rhamno_transf PF11316.8 CEG35814.1 - 0.38 10.1 4.1 0.48 9.8 2.6 1.7 1 1 1 2 2 2 0 Putative rhamnosyl transferase Retrotran_gag_2 PF14223.6 CEG35815.1 - 4.4e-15 55.6 0.1 5.1e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Lentiviral_Tat PF02998.14 CEG35816.1 - 0.13 12.3 1.5 1.2 9.2 0.5 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein EST1_DNA_bind PF10373.9 CEG35817.1 - 1.2e-47 162.8 0.4 3.1e-47 161.4 0.4 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CEG35817.1 - 2e-13 51.2 3.8 2e-13 51.2 3.8 2.3 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_1 PF00515.28 CEG35817.1 - 0.037 13.8 0.2 0.65 9.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0240 PF06784.11 CEG35818.1 - 6.5e-07 29.6 0.0 8.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Neugrin PF06413.11 CEG35818.1 - 0.006 16.6 0.3 0.054 13.5 0.0 2.0 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 CEG35818.1 - 0.0089 16.2 0.0 0.026 14.7 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Hydrolase PF00702.26 CEG35819.1 - 2.7e-14 54.0 0.1 4.9e-14 53.1 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG35819.1 - 1.1e-10 42.3 0.0 2.5e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CEG35819.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 CEG35819.1 - 5.2e-06 26.0 0.1 1.2e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 CEG35819.1 - 0.023 14.8 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Borrelia_REV PF03978.13 CEG35819.1 - 0.057 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein HTH_IclR PF09339.10 CEG35819.1 - 0.087 12.6 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain Brix PF04427.18 CEG35820.1 - 3.9e-38 131.5 0.2 5.9e-38 130.9 0.2 1.3 1 0 0 1 1 1 1 Brix domain Bud13 PF09736.9 CEG35820.1 - 0.038 14.4 1.7 0.065 13.6 1.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex BRO1 PF03097.18 CEG35821.1 - 1.5e-101 340.1 0.5 2.9e-101 339.1 0.5 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEG35821.1 - 4.2e-56 190.4 18.8 4.2e-56 190.4 18.8 2.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV SRP54 PF00448.22 CEG35821.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Prefoldin PF02996.17 CEG35824.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF3567 PF12091.8 CEG35824.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Gly_kinase PF02595.15 CEG35824.1 - 0.18 10.8 0.0 0.21 10.6 0.0 1.0 1 0 0 1 1 1 0 Glycerate kinase family SKIP_SNW PF02731.15 CEG35825.1 - 6.2e-72 240.5 2.1 6.2e-72 240.5 2.1 2.1 2 0 0 2 2 2 1 SKIP/SNW domain DUF572 PF04502.13 CEG35825.1 - 0.56 9.8 15.1 0.055 13.1 10.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Presenilin PF01080.17 CEG35825.1 - 8.6 5.0 8.7 14 4.3 8.7 1.3 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 CEG35826.1 - 2.1e-05 24.3 0.6 2.5e-05 24.0 0.6 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit FPP PF05911.11 CEG35826.1 - 0.0024 16.2 0.0 0.0029 15.9 0.0 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil MscS_porin PF12795.7 CEG35826.1 - 0.0092 15.6 0.3 0.027 14.0 0.3 1.8 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain KxDL PF10241.9 CEG35826.1 - 0.012 15.9 0.5 1.4 9.2 0.0 3.0 2 1 1 4 4 3 0 Uncharacterized conserved protein TMF_DNA_bd PF12329.8 CEG35826.1 - 0.016 15.2 8.0 5 7.2 0.5 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 CEG35826.1 - 0.036 14.3 9.6 0.27 11.5 4.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 CEG35826.1 - 0.039 12.1 4.0 0.047 11.9 4.0 1.1 1 0 0 1 1 1 0 HOOK protein ABC_tran_CTD PF16326.5 CEG35826.1 - 0.051 13.8 10.6 0.089 13.0 0.6 3.7 2 1 3 5 5 5 0 ABC transporter C-terminal domain Spc7 PF08317.11 CEG35826.1 - 0.055 12.4 0.3 0.56 9.0 0.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 CEG35826.1 - 0.066 13.4 2.9 9 6.5 0.6 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2802 PF10975.8 CEG35826.1 - 0.071 13.2 5.1 32 4.7 0.1 4.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2802) Tropomyosin PF00261.20 CEG35826.1 - 0.086 12.2 15.9 0.068 12.5 12.1 2.4 2 1 0 2 2 2 0 Tropomyosin MPS2 PF17060.5 CEG35826.1 - 0.095 12.0 7.4 0.27 10.5 7.0 1.9 1 1 0 1 1 1 0 Monopolar spindle protein 2 DHR10 PF18595.1 CEG35826.1 - 0.24 11.4 13.3 0.41 10.7 3.9 2.9 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain UPF0183 PF03676.14 CEG35826.1 - 0.27 10.5 0.1 0.39 10.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) CorA PF01544.18 CEG35826.1 - 0.34 10.2 6.7 1.5 8.1 5.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Lebercilin PF15619.6 CEG35826.1 - 0.41 10.3 13.7 2.4 7.8 2.7 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MetOD2 PF18548.1 CEG35826.1 - 0.56 10.3 5.9 13 6.0 0.7 3.4 1 1 2 3 3 3 0 Metanogen output domain 2 CdvA PF18822.1 CEG35826.1 - 0.94 9.3 11.1 2.6 7.9 0.1 3.9 2 1 3 5 5 5 0 CdvA-like coiled-coil domain XhlA PF10779.9 CEG35826.1 - 1.5 9.1 3.9 7.3 6.9 0.1 3.2 2 1 2 4 4 4 0 Haemolysin XhlA Uds1 PF15456.6 CEG35826.1 - 2 8.6 9.6 2.7 8.2 1.8 3.0 1 1 1 2 2 2 0 Up-regulated During Septation SlyX PF04102.12 CEG35826.1 - 2.2 9.0 7.6 28 5.4 0.1 3.5 1 1 1 2 2 2 0 SlyX FUSC PF04632.12 CEG35826.1 - 2.7 6.4 5.3 3.4 6.1 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.11 CEG35826.1 - 3.5 8.1 7.0 13 6.3 0.3 4.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) MutS_IV PF05190.18 CEG35826.1 - 4.8 7.6 9.5 2.8 8.4 0.1 3.9 2 1 2 4 4 4 0 MutS family domain IV Tropomyosin_1 PF12718.7 CEG35826.1 - 8.4 6.5 16.0 1.1 9.4 7.4 2.9 2 1 0 2 2 2 0 Tropomyosin like PDDEXK_3 PF13366.6 CEG35828.1 - 4.3e-31 107.7 0.0 6.8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 CEG35828.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Got1 PF04178.12 CEG35829.1 - 3.4e-31 108.0 11.7 4.6e-31 107.6 10.6 1.6 1 1 1 2 2 2 1 Got1/Sft2-like family TMEM43 PF07787.12 CEG35829.1 - 0.3 10.4 1.1 0.41 10.0 1.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 MMPL PF03176.15 CEG35829.1 - 0.64 8.9 7.0 0.73 8.7 6.1 1.6 2 0 0 2 2 2 0 MMPL family FA_desaturase PF00487.24 CEG35829.1 - 0.72 9.6 2.2 1.1 9.0 2.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase CCB1 PF12046.8 CEG35829.1 - 1.4 8.2 4.8 2.5 7.4 4.8 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B PrgI PF12666.7 CEG35829.1 - 6.9 7.5 13.5 5.3 7.8 5.9 2.2 1 1 0 2 2 2 0 PrgI family protein Arteri_Gl PF00951.18 CEG35830.1 - 0.028 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Fungal_trans_2 PF11951.8 CEG35830.1 - 0.029 13.2 0.0 0.029 13.2 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 CEG35832.1 - 5.4e-72 242.7 0.0 6.9e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CEG35832.1 - 9.6e-24 83.1 1.7 9.6e-24 83.1 1.7 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CEG35832.1 - 8.8e-19 68.3 0.7 2.2e-18 67.0 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 CEG35834.1 - 1.3e-44 149.9 0.0 1.3e-17 63.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG35834.1 - 0.00019 21.4 0.0 0.0056 16.6 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CEG35834.1 - 0.0015 18.5 0.0 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 CEG35834.1 - 0.0017 18.4 0.1 1.5 9.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 CEG35834.1 - 0.013 15.8 0.0 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 CEG35835.1 - 1.6e-05 25.5 10.7 0.68 10.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35835.1 - 0.00067 19.9 1.4 1.6 9.1 0.2 3.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_16 PF10294.9 CEG35836.1 - 3.8e-11 43.0 0.0 3.1e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Lysine methyltransferase 2OG-FeII_Oxy_2 PF13532.6 CEG35836.1 - 1.1e-06 28.9 0.1 2.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PrmA PF06325.13 CEG35836.1 - 7.7e-05 22.2 0.2 0.00019 21.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG35836.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Asp_Arg_Hydrox PF05118.15 CEG35836.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase malic PF00390.19 CEG35836.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Pkinase_Tyr PF07714.17 CEG35837.1 - 4.8e-46 157.1 0.0 6e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG35837.1 - 4.4e-32 111.5 0.0 1.1e-30 106.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain RTT107_BRCT_5 PF16770.5 CEG35840.1 - 1.1e-16 60.5 0.2 2.5e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CEG35840.1 - 2.5e-07 31.0 0.6 0.028 14.8 0.0 3.5 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain DUF3945 PF13101.6 CEG35840.1 - 0.032 13.9 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) BAH PF01426.18 CEG35840.1 - 0.04 13.8 0.1 0.67 9.8 0.0 2.9 3 0 0 3 3 3 0 BAH domain NFACT-C PF11923.8 CEG35842.1 - 0.27 11.2 1.2 1.5 8.8 0.0 2.5 3 0 0 3 3 3 0 NFACT protein C-terminal domain Fes1 PF08609.10 CEG35842.1 - 2.2 9.2 6.2 1 10.3 4.0 1.6 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Peptidase_C69 PF03577.15 CEG35844.1 - 2.2e-55 188.2 0.0 9.5e-55 186.1 0.0 2.1 2 1 0 2 2 2 1 Peptidase family C69 DEAD PF00270.29 CEG35845.1 - 1.9e-43 148.2 0.5 1.1e-42 145.8 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG35845.1 - 9.7e-20 71.0 0.1 3.4e-18 66.0 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG35845.1 - 3.5e-09 36.9 0.0 6.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CEG35845.1 - 0.063 13.5 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) AAA_22 PF13401.6 CEG35845.1 - 0.13 12.5 0.8 0.55 10.5 0.8 2.2 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 CEG35846.1 - 2.4e-23 83.0 0.5 3.5e-23 82.5 0.5 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CBP_BcsQ PF06564.12 CEG35846.1 - 0.046 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ HSF_DNA-bind PF00447.17 CEG35848.1 - 8e-20 71.3 3.4 1.1e-19 70.8 3.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding RCC1 PF00415.18 CEG35850.1 - 7.9e-32 109.7 0.3 1.8e-15 57.3 0.3 3.1 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG35850.1 - 3e-10 39.6 14.5 5.8e-06 26.0 1.7 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 CEG35850.1 - 0.23 11.5 1.4 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain NAGLU PF05089.12 CEG35851.1 - 4.6e-124 413.7 6.5 6.1e-124 413.3 6.5 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 CEG35851.1 - 6.2e-76 255.5 8.1 9.4e-76 254.9 8.1 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 CEG35851.1 - 5.9e-19 67.6 0.0 2.2e-18 65.8 0.0 2.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DLIC PF05783.11 CEG35852.1 - 3.1e-33 115.3 0.7 7.5e-33 114.1 0.7 1.6 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 CEG35852.1 - 0.00038 20.1 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 CEG35852.1 - 0.001 18.7 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 2 Ras family AAA_16 PF13191.6 CEG35852.1 - 0.013 15.8 0.3 0.08 13.3 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 CEG35852.1 - 0.022 15.0 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CEG35852.1 - 0.035 14.4 0.0 0.49 10.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CEG35852.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 CEG35852.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cas_Cas6 PF01881.16 CEG35852.1 - 0.18 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Spc24 PF08286.11 CEG35853.1 - 1.4e-05 25.3 5.6 0.00036 20.7 0.1 2.3 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 CEG35853.1 - 0.0057 16.7 8.4 0.0057 16.7 8.4 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein CREPT PF16566.5 CEG35853.1 - 0.0094 16.1 6.6 0.047 13.9 4.3 2.1 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Caps_synth_GfcC PF06251.11 CEG35853.1 - 0.028 14.1 1.1 0.038 13.6 1.1 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Phage_GPO PF05929.11 CEG35853.1 - 0.062 12.9 3.9 0.052 13.2 2.5 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin-6_N PF09177.11 CEG35853.1 - 0.12 13.0 3.1 0.71 10.5 2.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3685 PF12452.8 CEG35853.1 - 2.4 7.8 4.6 2.7 7.7 2.9 1.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3685) TPR_2 PF07719.17 CEG35854.1 - 1.1e-25 87.6 21.8 0.002 18.1 0.0 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 CEG35854.1 - 7.7e-21 73.0 13.4 0.0041 17.8 0.1 10.6 7 1 4 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEG35854.1 - 1.1e-20 72.0 21.5 0.021 15.0 0.0 10.1 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEG35854.1 - 1.1e-18 67.5 19.9 0.0003 21.3 0.5 8.5 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG35854.1 - 1e-16 59.9 12.0 0.0042 16.9 0.0 8.8 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEG35854.1 - 8.1e-16 56.8 16.7 0.0085 16.1 0.0 10.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG35854.1 - 1.1e-15 57.6 25.0 0.011 15.9 0.4 10.1 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEG35854.1 - 1e-12 48.4 8.3 0.0034 18.0 0.1 7.5 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG35854.1 - 2e-12 46.9 18.4 0.81 10.5 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG35854.1 - 1.3e-11 44.5 21.0 1.9e-07 31.2 0.6 6.8 8 1 0 8 8 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEG35854.1 - 1.2e-08 34.5 11.8 0.035 13.8 0.0 8.4 8 1 1 9 9 9 3 TPR repeat TPR_17 PF13431.6 CEG35854.1 - 1.2e-08 34.7 12.2 0.016 15.6 0.0 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG35854.1 - 1.1e-07 31.9 12.5 0.00092 19.3 0.5 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 CEG35854.1 - 1.4e-06 28.6 10.7 1 9.8 0.1 6.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG35854.1 - 0.00014 21.6 15.7 7 6.7 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat BTAD PF03704.17 CEG35854.1 - 0.00017 22.1 0.8 0.57 10.6 0.1 2.9 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 CEG35854.1 - 0.00099 18.6 5.8 0.046 13.1 1.1 3.6 4 0 0 4 4 4 1 MalT-like TPR region ChAPs PF09295.10 CEG35854.1 - 0.001 18.2 3.4 0.41 9.6 0.1 3.6 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 CEG35854.1 - 0.0011 18.3 5.7 0.57 9.3 4.2 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat YL1 PF05764.13 CEG35854.1 - 0.0038 17.4 0.6 0.0068 16.6 0.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Ribonuc_red_lgN PF00317.21 CEG35854.1 - 0.012 15.6 0.3 0.17 11.9 0.1 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Profilin PF00235.19 CEG35855.1 - 0.00037 20.8 0.0 0.00048 20.4 0.0 1.2 1 0 0 1 1 1 1 Profilin SAP18 PF06487.12 CEG35856.1 - 1.2e-27 96.8 0.0 2.5e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) SRP14 PF02290.15 CEG35856.1 - 2.4e-13 50.2 1.8 7.1e-13 48.7 1.8 1.8 1 0 0 1 1 1 1 Signal recognition particle 14kD protein AAA PF00004.29 CEG35857.1 - 0.00058 20.3 0.0 0.0024 18.3 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEG35857.1 - 0.0047 16.9 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CEG35857.1 - 0.01 16.2 0.1 0.055 13.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEG35857.1 - 0.029 14.7 0.3 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG35857.1 - 0.1 12.8 0.0 0.57 10.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain Comm PF15957.5 CEG35859.1 - 0.084 13.2 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Commissureless Mitoc_mL59 PF18126.1 CEG35860.1 - 8.1e-11 42.3 6.3 2e-10 41.1 6.2 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 SSXT PF05030.12 CEG35861.1 - 1.6e-18 66.0 3.8 2.5e-18 65.5 3.8 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Elf4 PF07011.11 CEG35861.1 - 0.095 12.6 2.3 0.24 11.3 2.3 1.9 1 1 0 1 1 1 0 Early Flowering 4 domain TFIIA PF03153.13 CEG35862.1 - 6.4 6.7 31.9 7.4 6.5 31.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-WRNIP1_ubi PF18279.1 CEG35864.1 - 0.059 14.0 1.8 0.72 10.6 0.7 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Pyr_redox_2 PF07992.14 CEG35866.1 - 3.4e-21 75.7 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 CEG35866.1 - 7.1e-15 55.5 0.0 1.3e-06 28.7 0.0 2.3 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 CEG35866.1 - 1.5e-09 38.2 0.0 7.1e-09 36.1 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEG35866.1 - 0.0011 18.6 0.4 0.69 9.4 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CEG35866.1 - 0.0079 15.4 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEG35866.1 - 0.036 14.3 0.4 15 5.9 0.0 3.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 CEG35866.1 - 0.082 13.0 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CEG35866.1 - 0.091 12.7 0.4 4.7 7.2 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding ThiF PF00899.21 CEG35866.1 - 0.21 10.9 0.4 0.62 9.4 0.6 1.6 2 0 0 2 2 2 0 ThiF family FYVE PF01363.21 CEG35868.1 - 0.00033 20.8 4.7 0.00075 19.6 4.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG35868.1 - 0.0017 18.5 3.9 0.0017 18.5 3.9 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger DNA_RNApol_7kD PF03604.13 CEG35868.1 - 0.86 9.3 6.4 1.9 8.2 6.4 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbon_6 PF10005.9 CEG35868.1 - 1.1 10.0 6.9 4.1 8.2 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CEG35868.1 - 2.2 8.6 5.6 0.45 10.8 1.3 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CEG35871.1 - 6.1e-05 23.1 13.2 0.00014 21.9 13.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG35871.1 - 0.0062 16.7 8.2 0.018 15.2 8.2 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 CEG35872.1 - 0.027 14.6 12.0 0.061 13.5 12.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger START PF01852.19 CEG35872.1 - 0.039 13.4 1.4 0.058 12.8 0.2 1.9 2 1 0 2 2 2 0 START domain zf-AN1 PF01428.16 CEG35872.1 - 2.1 8.6 5.0 6.4 7.0 5.0 1.9 1 0 0 1 1 1 0 AN1-like Zinc finger C1_1 PF00130.22 CEG35872.1 - 4 7.4 8.6 4.4 7.3 5.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 CEG35872.1 - 5.3 7.3 11.7 26 5.0 11.7 2.2 1 1 0 1 1 1 0 FYVE-type zinc finger IBN_N PF03810.19 CEG35873.1 - 2.8e-06 27.2 0.8 1.4e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF5106 PF17127.4 CEG35873.1 - 0.12 12.7 3.7 5.2 7.3 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF5106) EMP24_GP25L PF01105.24 CEG35877.1 - 3.9e-54 183.4 0.2 4.8e-54 183.1 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BicD PF09730.9 CEG35877.1 - 0.0045 15.5 0.0 0.0052 15.3 0.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DASH_Dad1 PF08649.10 CEG35878.1 - 3.2e-15 56.0 2.0 3.8e-15 55.8 2.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SUV3_C PF12513.8 CEG35878.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF2461 PF09365.10 CEG35878.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Asp_protease PF09668.10 CEG35879.1 - 4e-57 191.4 0.3 7.5e-57 190.5 0.3 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG35879.1 - 6.6e-22 77.9 0.0 3e-21 75.8 0.0 2.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DnaJ PF00226.31 CEG35879.1 - 9.1e-14 51.3 0.2 2.1e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.31 CEG35879.1 - 8.7e-11 41.5 0.2 3.4e-10 39.6 0.2 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.6 CEG35879.1 - 2.9e-10 40.7 0.0 1.2e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 CEG35879.1 - 4.5e-09 35.9 0.1 1.1e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG35879.1 - 3.7e-06 26.7 0.6 1e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 CEG35879.1 - 0.00026 20.8 0.1 0.00076 19.3 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 CEG35879.1 - 0.0033 17.2 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEG35879.1 - 0.04 14.2 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Iron_permease PF04120.12 CEG35879.1 - 1.3 8.8 5.2 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Low affinity iron permease Pro_CA PF00484.19 CEG35881.1 - 1.4e-48 165.2 0.9 1.4e-48 165.2 0.9 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Ret2_MD PF18528.1 CEG35881.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Pro_CA PF00484.19 CEG35882.1 - 1.4e-48 165.2 0.1 1.4e-48 165.2 0.1 1.8 3 0 0 3 3 3 1 Carbonic anhydrase EcoEI_R_C PF08463.10 CEG35882.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 EcoEI R protein C-terminal Exo84_C PF16528.5 CEG35883.1 - 2.4e-17 63.4 2.7 2.5e-17 63.4 0.7 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CEG35883.1 - 3.9e-13 49.3 0.8 2.4e-12 46.7 0.5 2.6 2 0 0 2 2 2 1 Vps51/Vps67 PH PF00169.29 CEG35883.1 - 5.8e-08 33.2 0.1 1.8e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG35883.1 - 0.022 15.0 0.3 0.074 13.3 0.3 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 CEG35883.1 - 0.023 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain COG2 PF06148.11 CEG35883.1 - 0.027 14.6 0.6 0.027 14.6 0.6 3.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CEG35883.1 - 0.032 14.4 0.1 0.032 14.4 0.1 3.4 3 1 0 3 3 3 0 Golgi transport complex subunit 5 RCC1 PF00415.18 CEG35884.1 - 6.9e-67 221.9 8.2 6.2e-11 42.8 0.1 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG35884.1 - 4.1e-30 102.9 27.0 3.5e-08 33.0 0.0 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_4 PF12763.7 CEG35884.1 - 9.8e-21 73.7 0.0 1.7e-10 40.8 0.0 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CEG35884.1 - 9.3e-09 34.2 0.0 0.0063 16.0 0.2 3.8 3 0 0 3 3 3 2 EF hand PHD PF00628.29 CEG35884.1 - 1.7e-07 31.0 13.7 5.2e-07 29.5 13.7 1.9 1 1 0 1 1 1 1 PHD-finger EF-hand_7 PF13499.6 CEG35884.1 - 2.9e-07 30.8 0.2 7.9e-05 23.0 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG35884.1 - 0.00017 21.3 0.0 0.11 12.5 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 CEG35884.1 - 0.018 14.6 0.7 0.17 11.5 0.7 2.5 2 0 0 2 2 2 0 EF hand Zf_RING PF16744.5 CEG35884.1 - 0.018 15.1 6.9 0.045 13.9 6.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-PHD-like PF15446.6 CEG35884.1 - 0.21 11.2 4.6 0.39 10.3 4.6 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CEG35884.1 - 0.74 9.8 9.4 1.7 8.6 9.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Siva PF05458.12 CEG35884.1 - 0.75 9.5 6.9 1.6 8.4 6.9 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Prim_Zn_Ribbon PF08273.12 CEG35884.1 - 8.2 6.8 10.5 1.4 9.3 4.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Ras PF00071.22 CEG35886.1 - 6.9e-64 214.3 0.3 8e-64 214.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG35886.1 - 8.3e-36 122.8 0.1 1.2e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG35886.1 - 7.5e-16 58.1 0.0 9e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG35886.1 - 4.1e-06 26.9 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEG35886.1 - 3.1e-05 23.5 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEG35886.1 - 0.00011 21.9 0.3 0.00038 20.1 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEG35886.1 - 0.0002 21.3 0.3 0.082 12.8 0.0 2.5 1 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CEG35886.1 - 0.0011 18.4 0.4 0.0017 17.8 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEG35886.1 - 0.0059 16.9 0.0 0.0091 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG35886.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CENP-M PF11111.8 CEG35886.1 - 0.027 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ABC_tran PF00005.27 CEG35886.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 CEG35886.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 CEG35886.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 CEG35886.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pro_CA PF00484.19 CEG35887.1 - 2.9e-48 164.1 0.2 4.4e-48 163.5 0.2 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Vac_Fusion PF02346.16 CEG35887.1 - 0.04 13.5 1.9 0.11 12.1 1.9 1.7 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF2540 PF10802.8 CEG35887.1 - 0.048 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Complex1_49kDa PF00346.19 CEG35887.1 - 0.064 12.3 0.1 0.19 10.8 0.1 1.7 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF563 PF04577.14 CEG35888.1 - 4.8e-05 23.6 0.0 8.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sugar_tr PF00083.24 CEG35889.1 - 3.7e-89 299.7 24.4 4.6e-89 299.4 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG35889.1 - 1.3e-31 109.8 45.8 1.2e-27 96.8 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CEG35889.1 - 0.0004 18.9 9.6 0.047 12.1 3.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 CEG35889.1 - 0.00075 18.5 17.0 0.0012 17.8 1.1 2.5 1 1 1 2 2 2 2 MFS_1 like family Herpes_pp38 PF04846.13 CEG35889.1 - 0.074 13.0 0.7 0.77 9.7 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein Med27 PF11571.8 CEG35891.1 - 6.2e-17 61.7 1.0 6.2e-17 61.7 1.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 6PF2K PF01591.18 CEG35891.1 - 0.099 11.9 0.6 7.1 5.9 0.0 2.9 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Retrotrans_gag PF03732.17 CEG35893.1 - 2.6e-09 37.2 0.0 3.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein LSM PF01423.22 CEG35894.1 - 8.4e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 LSM domain SAGA-Tad1 PF12767.7 CEG35895.1 - 3.4e-13 49.9 2.5 4e-13 49.7 2.5 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Fer4 PF00037.27 CEG35896.1 - 4.2e-14 51.7 17.5 1.6e-08 34.0 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CEG35896.1 - 1.1e-12 48.4 10.8 1.7e-12 47.7 10.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CEG35896.1 - 3.6e-11 43.8 5.5 3.7e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CEG35896.1 - 1.9e-09 37.5 31.6 8e-06 25.9 12.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEG35896.1 - 1.9e-08 34.3 10.5 3.1e-08 33.6 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CEG35896.1 - 2.6e-08 33.9 21.9 4.6e-06 26.6 12.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CEG35896.1 - 3.1e-07 30.2 17.8 0.00036 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CEG35896.1 - 1.2e-06 28.9 20.2 0.00027 21.3 12.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CEG35896.1 - 1.2e-06 28.2 12.1 0.0025 17.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CEG35896.1 - 1.1e-05 25.5 12.0 0.00045 20.5 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CEG35896.1 - 0.00037 21.0 11.2 0.03 14.9 12.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CEG35896.1 - 0.0052 17.0 5.5 0.64 10.3 0.4 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 CEG35896.1 - 0.014 15.9 14.7 0.64 10.6 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CEG35896.1 - 0.032 14.4 8.5 0.98 9.6 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 CEG35896.1 - 0.18 12.8 16.3 0.31 12.1 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 CEG35896.1 - 0.28 11.4 5.7 1.1 9.4 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CEG35896.1 - 0.88 10.5 11.9 2.7 8.9 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain RPA43_OB PF17875.1 CEG35897.1 - 2.3e-07 31.5 0.1 1.1e-05 26.1 0.0 3.5 2 2 1 3 3 3 2 RPA43 OB domain in RNA Pol I TBCC PF07986.12 CEG35898.1 - 2.7e-28 98.1 0.0 5.4e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_GLY PF01302.25 CEG35898.1 - 3.9e-18 65.2 0.0 7.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain TBCC_N PF16752.5 CEG35898.1 - 1.9e-17 63.8 3.9 1.9e-17 63.8 3.9 1.8 2 1 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain BTB_2 PF02214.22 CEG35899.1 - 9.5e-17 61.1 0.1 3.1e-16 59.5 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain CHASE2 PF05226.11 CEG35899.1 - 0.055 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain Prog_receptor PF02161.15 CEG35900.1 - 0.091 11.5 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Progesterone receptor TUDOR PF00567.24 CEG35901.1 - 0.00017 21.6 0.3 0.33 11.0 0.0 2.7 2 1 1 3 3 3 2 Tudor domain SMN PF06003.12 CEG35901.1 - 0.0095 15.2 0.2 0.022 14.1 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) PAC4 PF16093.5 CEG35902.1 - 7.3e-15 54.9 0.1 1.9e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 TAL_effector PF03377.13 CEG35903.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 TAL effector repeat SMC_N PF02463.19 CEG35904.1 - 2.6e-61 206.8 10.3 8e-61 205.3 10.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEG35904.1 - 1.8e-28 99.2 0.4 1.7e-27 96.0 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CEG35904.1 - 1.6e-18 67.9 5.7 1.6e-18 67.9 5.7 7.0 2 2 3 6 6 3 1 AAA domain AAA_21 PF13304.6 CEG35904.1 - 7e-13 49.0 1.6 4.5e-08 33.3 0.8 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEG35904.1 - 2.8e-08 33.4 0.0 6.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fungal_trans_2 PF11951.8 CEG35904.1 - 0.005 15.7 1.0 0.013 14.4 1.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_27 PF13514.6 CEG35904.1 - 0.026 14.1 0.0 0.026 14.1 0.0 4.3 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CEG35904.1 - 0.053 13.8 0.2 4.3 7.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain Repressor_Mnt PF11423.8 CEG35904.1 - 1.7 8.5 7.6 1.1 9.1 0.3 3.7 4 0 0 4 4 4 0 Regulatory protein Mnt HetR_C PF18460.1 CEG35904.1 - 1.8 8.5 7.7 5.4 7.0 0.1 3.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain ABC_tran PF00005.27 CEG35904.1 - 9 6.8 35.6 12 6.4 0.0 7.2 3 3 0 5 5 5 0 ABC transporter WD40 PF00400.32 CEG35905.1 - 9.7e-52 171.8 14.7 1.2e-06 29.1 0.1 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG35905.1 - 4.7e-19 68.5 0.2 0.003 17.8 0.0 6.8 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG35905.1 - 1.9e-08 34.4 0.1 0.18 11.7 0.0 4.9 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEG35905.1 - 8.2e-07 28.6 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain IKI3 PF04762.12 CEG35905.1 - 0.00086 17.4 0.1 0.84 7.5 0.0 3.4 3 1 0 3 3 3 2 IKI3 family Frtz PF11768.8 CEG35905.1 - 0.0009 17.7 0.0 2.2 6.5 0.0 3.1 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CEG35905.1 - 0.0018 17.3 0.0 4.2 6.3 0.0 3.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEG35905.1 - 0.029 14.3 0.6 22 5.1 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat NUDIX PF00293.28 CEG35909.1 - 7.9e-14 51.8 0.0 1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Rhodanese PF00581.20 CEG35910.1 - 9.9e-08 32.5 0.0 1.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 CEG35911.1 - 0.044 14.7 0.5 39 5.3 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF4233 PF14017.6 CEG35912.1 - 0.66 10.3 5.6 0.92 9.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Asp PF00026.23 CEG35915.1 - 1.8e-63 214.9 0.0 2.4e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG35915.1 - 6e-13 49.4 0.2 9.4e-10 39.0 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG35915.1 - 0.0017 18.1 0.2 0.0043 16.9 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal zf-C2H2 PF00096.26 CEG35916.1 - 5.4e-16 58.1 25.2 0.00039 20.7 3.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEG35916.1 - 1.2e-15 57.1 22.7 6.1e-06 26.4 1.1 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEG35916.1 - 9e-10 38.6 23.6 0.015 16.0 0.7 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 CEG35916.1 - 0.039 14.3 4.9 2.3 8.7 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CEG35916.1 - 0.079 13.1 4.4 0.35 11.0 0.0 2.8 2 1 0 2 2 2 0 Aberrant zinc-finger BBP1_N PF15271.6 CEG35916.1 - 0.11 13.3 0.5 0.36 11.6 0.5 1.9 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein FOXP-CC PF16159.5 CEG35916.1 - 0.21 12.3 8.4 2.2 8.9 0.3 3.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 CEG35916.1 - 1.3 9.8 12.3 5.5 7.8 3.6 3.9 2 1 1 3 3 3 0 TRAF-type zinc finger zf-C2H2_3rep PF18868.1 CEG35916.1 - 1.3 9.7 11.5 5.5 7.7 0.7 3.6 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CEG35916.1 - 1.8 8.9 9.7 0.31 11.4 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding tRNA-synt_1b PF00579.25 CEG35918.1 - 1.4e-67 228.1 0.1 3e-67 227.0 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 CEG35918.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) DEAD PF00270.29 CEG35919.1 - 1.8e-17 63.7 0.0 1e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CEG35919.1 - 1.1e-16 61.3 7.9 1.1e-16 61.3 7.9 2.6 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 CEG35919.1 - 6.9e-15 55.4 0.0 3.6e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 CEG35919.1 - 4.3e-14 52.2 0.0 3.4e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 HRDC domain RQC PF09382.10 CEG35919.1 - 2.4e-12 46.6 0.2 7e-12 45.1 0.2 1.8 1 0 0 1 1 1 1 RQC domain zf-GRF PF06839.12 CEG35919.1 - 2.5e-06 27.5 0.8 6.1e-06 26.2 0.8 1.7 1 0 0 1 1 1 1 GRF zinc finger zf-CCCH_6 PF18585.1 CEG35919.1 - 0.042 13.7 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF5308 PF17233.2 CEG35919.1 - 0.045 14.0 0.8 0.17 12.1 0.8 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5308) TSGP1 PF07771.11 CEG35919.1 - 0.094 12.9 1.1 0.29 11.3 1.1 1.8 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF4629 PF15442.6 CEG35919.1 - 8.3 6.6 18.1 0.04 14.1 4.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4629) Pantoate_ligase PF02569.15 CEG35920.1 - 5.9e-98 327.3 0.0 6.8e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Kinesin PF00225.23 CEG35921.1 - 6.4e-94 314.6 0.6 1.1e-93 313.9 0.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG35921.1 - 2e-23 83.0 0.3 6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding TSC22 PF01166.18 CEG35921.1 - 0.052 13.9 3.1 2.7 8.4 0.3 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family Pox_A_type_inc PF04508.12 CEG35921.1 - 0.49 10.3 3.5 0.68 9.9 0.6 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RXLR_WY PF18634.1 CEG35922.1 - 0.033 14.1 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain RXLR_WY PF18634.1 CEG35923.1 - 0.037 13.9 0.5 0.074 13.0 0.5 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain DUF445 PF04286.12 CEG35923.1 - 0.065 13.0 0.8 0.077 12.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) E1_dh PF00676.20 CEG35923.1 - 0.091 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component AFG1_ATPase PF03969.16 CEG35924.1 - 2e-89 300.0 3.6 1.6e-84 283.9 1.4 2.2 2 0 0 2 2 2 2 AFG1-like ATPase TsaE PF02367.17 CEG35924.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CEG35924.1 - 0.021 15.1 0.1 0.12 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG35924.1 - 0.038 14.4 0.3 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF2852 PF11014.8 CEG35924.1 - 0.053 13.7 0.4 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Sigma54_activat PF00158.26 CEG35924.1 - 0.12 12.0 0.1 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain KR PF08659.10 CEG35925.1 - 0.036 14.0 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 KR domain Spiralin PF05215.13 CEG35925.1 - 0.036 13.4 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 Spiralin PDCD2_C PF04194.13 CEG35926.1 - 4.5e-35 121.3 0.8 4.5e-35 121.3 0.8 2.8 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 CEG35926.1 - 2.3e-08 34.0 8.5 2.3e-08 34.0 8.5 3.7 4 1 1 5 5 5 1 MYND finger zf-HIT PF04438.16 CEG35926.1 - 0.0018 18.1 4.3 0.0018 18.1 4.3 3.8 5 0 0 5 5 5 1 HIT zinc finger zf-Mss51 PF13824.6 CEG35926.1 - 4 7.6 10.2 2.5 8.3 6.7 2.7 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DAO PF01266.24 CEG35927.1 - 2.3e-59 201.8 0.0 2.6e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CEG35927.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CEG35927.1 - 0.0071 16.6 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEG35927.1 - 0.011 14.9 1.6 0.016 14.3 1.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CEG35927.1 - 0.013 14.8 0.8 0.092 12.0 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG35927.1 - 0.026 13.2 0.2 0.11 11.1 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 CEG35927.1 - 0.028 14.3 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 CEG35927.1 - 0.031 13.6 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 CEG35927.1 - 0.044 13.0 0.2 0.12 11.6 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CEG35927.1 - 0.093 13.3 0.5 0.23 12.0 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 CEG35927.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 CEG35927.1 - 0.18 11.0 0.3 0.28 10.4 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEG35927.1 - 0.22 10.8 0.2 3.6 6.7 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain MurJ PF03023.14 CEG35928.1 - 0.0088 14.7 1.4 0.015 13.9 1.4 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ OAD_gamma PF04277.13 CEG35928.1 - 0.32 11.6 2.4 0.69 10.5 2.4 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain HPS6 PF15702.5 CEG35930.1 - 0.11 10.5 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein ATP-gua_PtransN PF02807.15 CEG35931.1 - 4.6e-28 97.4 1.0 6.7e-28 96.9 0.2 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.19 CEG35931.1 - 0.00023 20.7 0.3 0.00042 19.9 0.0 1.5 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain Kazal_3 PF18434.1 CEG35932.1 - 0.047 13.5 1.6 28 4.5 0.0 3.5 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain LRR_9 PF14580.6 CEG35934.1 - 1.1e-09 38.0 0.2 4.3e-09 36.1 0.2 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CEG35934.1 - 0.012 15.3 2.4 0.012 15.3 2.4 2.8 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CEG35934.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) UQ_con PF00179.26 CEG35935.1 - 7.2e-43 145.6 0.0 1.5e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glycos_transf_1 PF00534.20 CEG35935.1 - 3.8e-12 46.1 0.0 1.5e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG35935.1 - 7e-11 42.7 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEG35935.1 - 0.013 15.9 0.0 0.044 14.2 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 Arabinose_Iso_C PF11762.8 CEG35935.1 - 0.026 14.3 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain PseudoU_synth_1 PF01416.20 CEG35936.1 - 2.1e-20 73.2 0.0 1.2e-14 54.6 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ank_4 PF13637.6 CEG35937.1 - 6.3e-23 80.8 0.2 5e-07 30.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG35937.1 - 4.9e-20 71.9 0.4 4.4e-17 62.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG35937.1 - 1.6e-19 69.7 0.2 1.1e-10 41.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG35937.1 - 7.3e-16 57.8 0.2 2e-06 28.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CEG35937.1 - 8.5e-16 56.5 0.0 0.0029 18.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Sec8_exocyst PF04048.14 CEG35938.1 - 2.3e-09 37.3 0.6 2.3e-09 37.3 0.6 3.9 5 0 0 5 5 5 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CEG35938.1 - 5.7e-07 29.1 5.3 1.3e-06 27.9 5.3 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2408 PF10303.9 CEG35938.1 - 0.2 12.2 5.0 1.9 9.1 0.0 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) TssC PF17541.2 CEG35939.1 - 0.31 9.8 3.2 0.4 9.5 3.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Presenilin PF01080.17 CEG35939.1 - 2.5 6.8 6.1 3.5 6.3 6.1 1.2 1 0 0 1 1 1 0 Presenilin DUF4706 PF15797.5 CEG35939.1 - 5.4 7.6 10.3 5.5 7.6 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) peroxidase PF00141.23 CEG35943.1 - 2.6e-08 33.8 0.1 3.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Retrotran_gag_2 PF14223.6 CEG35947.1 - 0.0018 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Gal11_ABD1 PF18535.1 CEG35947.1 - 0.009 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Gal11 activator-binding domain (ABD1) Ribo_biogen_C PF04034.13 CEG35948.1 - 5.5e-51 171.6 0.0 8.8e-51 170.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CEG35948.1 - 9.2e-09 35.0 0.6 1.7e-08 34.1 0.6 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MTHFR PF02219.17 CEG35949.1 - 7.6e-92 307.7 0.0 1e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SYCP2_ARLD PF18581.1 CEG35952.1 - 0.00011 22.2 2.5 0.00011 22.2 2.5 2.3 2 1 0 3 3 3 1 Synaptonemal complex 2 armadillo-repeat-like domain Utp12 PF04003.12 CEG35952.1 - 0.098 13.0 3.5 0.66 10.3 0.2 3.4 3 1 1 4 4 4 0 Dip2/Utp12 Family Tn7_Tnp_TnsA_C PF08721.11 CEG35952.1 - 0.11 13.1 0.4 0.11 13.1 0.4 2.7 3 0 0 3 3 3 0 TnsA endonuclease C terminal APG12 PF04110.13 CEG35952.1 - 3.1 8.2 6.2 64 4.1 0.3 3.7 1 1 3 4 4 4 0 Ubiquitin-like autophagy protein Apg12 His_Phos_1 PF00300.22 CEG35955.1 - 4.5e-15 55.9 0.3 2e-09 37.4 0.1 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) GGA_N-GAT PF18308.1 CEG35955.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 GGA N-GAT domain WD40 PF00400.32 CEG35956.1 - 2.1e-18 66.4 20.8 0.00074 20.3 0.0 9.1 8 2 0 8 8 8 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CEG35956.1 - 0.029 13.1 0.0 6.9 5.3 0.0 3.5 3 2 1 4 4 4 0 Nup133 N terminal like Choline_sulf_C PF12411.8 CEG35956.1 - 0.13 12.1 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal MnmE_helical PF12631.7 CEG35957.1 - 4.2e-48 164.3 2.3 5.2e-48 163.9 2.3 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CEG35957.1 - 4.4e-37 126.9 0.0 1.2e-36 125.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CEG35957.1 - 1.2e-19 70.5 0.1 2.3e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG35957.1 - 7.2e-10 38.6 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEG35957.1 - 7.1e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family cobW PF02492.19 CEG35957.1 - 0.00029 20.5 1.6 0.015 14.9 0.5 2.6 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CEG35957.1 - 0.00033 20.4 0.0 0.0015 18.3 0.1 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CEG35957.1 - 0.0011 18.9 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CEG35957.1 - 0.0021 18.6 0.7 0.0049 17.4 0.7 1.8 1 1 0 1 1 1 1 ABC transporter MMR_HSR1_Xtn PF16897.5 CEG35957.1 - 0.0034 17.4 0.1 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 CEG35957.1 - 0.02 15.4 0.0 0.21 12.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEG35957.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG35957.1 - 0.12 12.6 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEG35957.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG35957.1 - 0.14 12.6 0.8 0.94 9.8 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 CEG35957.1 - 0.15 11.9 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain MeaB PF03308.16 CEG35957.1 - 0.36 9.8 4.2 0.74 8.7 1.8 2.5 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 CEG35958.1 - 3.6e-05 23.4 0.4 0.024 14.2 0.0 2.8 3 0 0 3 3 3 2 Ras family AAA_28 PF13521.6 CEG35958.1 - 0.00085 19.6 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 CEG35958.1 - 0.074 13.3 2.2 0.4 10.9 0.0 3.1 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Leu_leader PF08054.11 CEG35959.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 Leucine operon leader peptide TGase_elicitor PF16683.5 CEG35962.1 - 1.1e-165 550.7 0.0 1.4e-165 550.5 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor Retinal PF15449.6 CEG35962.1 - 0.68 7.7 19.0 0.96 7.1 19.0 1.1 1 0 0 1 1 1 0 Retinal protein Cellulase PF00150.18 CEG35963.1 - 3.5e-19 69.3 6.8 4.6e-19 68.9 6.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Transket_pyr PF02779.24 CEG35964.1 - 1.3e-62 210.6 0.0 2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEG35964.1 - 1.3e-55 187.2 0.0 2.7e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 CEG35964.1 - 3.7e-54 183.7 0.0 5.7e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 CEG35964.1 - 3.3e-17 61.8 1.2 3.3e-17 61.8 1.2 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CEG35964.1 - 0.00093 19.1 0.0 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 Sec34 PF04136.15 CEG35966.1 - 4.3e-15 55.9 5.2 1.7e-07 31.2 0.0 3.8 3 1 1 4 4 4 2 Sec34-like family LepB_N PF18640.1 CEG35966.1 - 0.2 11.2 1.7 2 8.0 0.8 2.7 3 0 0 3 3 3 0 LepB N-terminal domain Laminin_II PF06009.12 CEG35966.1 - 0.49 10.4 5.2 0.74 9.8 0.2 3.6 3 2 1 4 4 4 0 Laminin Domain II APCDDC PF14921.6 CEG35966.1 - 3.6 7.0 6.6 3.9 6.9 0.2 2.8 3 0 0 3 3 3 0 Adenomatosis polyposis coli down-regulated 1 DUF1664 PF07889.12 CEG35966.1 - 3.8 7.6 6.5 3.1 7.9 0.3 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CEG35967.1 - 6.6e-06 24.4 0.4 6.6e-06 24.4 0.4 4.0 4 1 1 5 5 5 2 Prominin DUF2207 PF09972.9 CEG35967.1 - 2.2e-05 23.4 9.3 0.011 14.5 0.3 3.1 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) SUR7 PF06687.12 CEG35967.1 - 5.5e-05 22.9 6.7 0.023 14.3 3.6 2.6 2 0 0 2 2 2 2 SUR7/PalI family Tweety PF04906.13 CEG35967.1 - 0.00074 18.3 9.3 0.06 12.0 1.0 2.6 3 0 0 3 3 3 2 Tweety Baculo_PEP_C PF04513.12 CEG35967.1 - 0.22 11.6 3.4 10 6.2 0.0 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ni_hydr_CYTB PF01292.20 CEG35967.1 - 0.47 10.0 5.6 0.44 10.1 2.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Ank_2 PF12796.7 CEG35972.1 - 5.2e-73 241.7 16.1 1.4e-14 54.4 0.3 7.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG35972.1 - 1.2e-62 207.1 32.5 1.6e-10 41.0 0.1 11.3 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG35972.1 - 2.9e-61 203.1 39.1 1.4e-09 38.3 0.2 10.7 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 CEG35972.1 - 3.3e-61 201.2 34.2 1.5e-05 25.2 0.3 13.3 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 CEG35972.1 - 2.5e-57 184.1 20.9 0.00014 22.0 0.0 13.2 13 0 0 13 13 13 11 Ankyrin repeat Ricin_B_lectin PF00652.22 CEG35975.1 - 2e-13 50.7 3.9 4.3e-13 49.6 3.9 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain HTH_Tnp_Tc5 PF03221.16 CEG35977.1 - 0.024 14.7 0.1 0.052 13.6 0.0 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Methyltransf_16 PF10294.9 CEG35978.1 - 5e-17 62.2 0.0 6.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEG35978.1 - 0.0015 18.1 0.1 0.0023 17.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain LRR_6 PF13516.6 CEG35979.1 - 8.2e-08 31.7 0.3 0.43 10.7 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CEG35979.1 - 3.9e-07 30.3 0.1 0.057 13.9 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG35979.1 - 0.6 9.9 4.4 29 4.5 1.2 4.2 3 1 0 3 3 3 0 Leucine rich repeat Sgf11_N PF18519.1 CEG35981.1 - 0.046 13.3 0.2 0.068 12.7 0.2 1.2 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain SBP_bac_11 PF13531.6 CEG35981.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein ABC2_membrane PF01061.24 CEG35982.1 - 8.3e-28 97.2 26.0 8.3e-28 97.2 26.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CEG35982.1 - 5.9e-27 94.9 0.1 8.9e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEG35982.1 - 5.7e-09 36.2 0.1 4.8e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG35982.1 - 2.5e-05 23.8 0.1 0.037 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG35982.1 - 0.00014 22.3 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CEG35982.1 - 0.00027 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CEG35982.1 - 0.003 17.5 0.1 0.0084 16.0 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CEG35982.1 - 0.0034 17.1 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CEG35982.1 - 0.0037 17.8 0.0 0.0077 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG35982.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 CEG35982.1 - 0.0077 14.9 0.5 0.86 8.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG35982.1 - 0.01 16.2 0.0 0.055 13.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CEG35982.1 - 0.015 15.8 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CEG35982.1 - 0.016 14.9 0.3 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase NACHT PF05729.12 CEG35982.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CEG35982.1 - 0.038 14.2 0.1 0.1 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEG35982.1 - 0.042 13.8 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 CEG35982.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 CEG35982.1 - 0.069 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CEG35982.1 - 0.086 12.6 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 CEG35982.1 - 0.11 12.7 0.2 0.19 12.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CEG35982.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG35982.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEG35982.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEG35982.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 CEG35982.1 - 0.2 11.7 0.2 0.54 10.3 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 CEG35983.1 - 2.8e-31 108.6 21.4 2.8e-31 108.6 21.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CEG35983.1 - 9.3e-24 84.5 0.1 1.4e-23 83.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEG35983.1 - 2.2e-06 27.7 0.0 0.044 13.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CEG35983.1 - 9.2e-06 25.0 19.6 9.2e-06 25.0 19.6 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 CEG35983.1 - 0.00012 22.5 0.1 0.00025 21.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEG35983.1 - 0.00049 19.8 0.2 0.0012 18.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CEG35983.1 - 0.00049 19.6 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CEG35983.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEG35983.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.6 CEG35983.1 - 0.0094 16.5 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEG35983.1 - 0.0097 16.3 0.0 0.037 14.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG35983.1 - 0.011 16.1 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEG35983.1 - 0.016 15.1 0.1 0.016 15.1 0.1 2.1 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 CEG35983.1 - 0.019 15.5 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEG35983.1 - 0.051 13.5 0.1 0.89 9.4 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 CEG35983.1 - 0.088 13.1 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEG35983.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CEG35983.1 - 0.14 12.3 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 CEG35983.1 - 0.14 11.9 0.3 0.77 9.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CEG35983.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 CEG35983.1 - 0.2 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase PDR_CDR PF06422.12 CEG35983.1 - 1.8 8.5 3.9 5.2 7.0 0.3 2.7 2 1 1 3 3 3 0 CDR ABC transporter RVT_2 PF07727.14 CEG35984.1 - 0.0015 18.3 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAP PF07174.11 CEG35984.1 - 0.015 14.8 1.6 0.019 14.5 1.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) LepB_N PF18640.1 CEG35985.1 - 0.074 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 LepB N-terminal domain Elicitin PF00964.17 CEG35986.1 - 1.7e-14 53.7 7.4 1.7e-14 53.7 7.4 1.9 2 1 1 3 3 3 1 Elicitin Gyro_capsid PF04162.12 CEG35987.1 - 0.011 14.3 0.0 0.012 14.2 0.0 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Retrotrans_gag PF03732.17 CEG35989.1 - 4.7e-09 36.4 0.0 6.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein SPATA6 PF14909.6 CEG35989.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Complex1_51K PF01512.17 CEG35991.1 - 5.1e-46 156.3 0.0 1.1e-45 155.2 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CEG35991.1 - 3.9e-29 100.5 0.1 7.5e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CEG35991.1 - 1.9e-08 34.0 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Y_phosphatase2 PF03162.13 CEG35992.1 - 2e-55 186.8 0.0 2.7e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEG35992.1 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CEG35992.1 - 5.3e-06 26.3 0.0 8.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG35992.1 - 0.00039 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Methyltransf_31 PF13847.6 CEG35992.1 - 0.056 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain G-patch_2 PF12656.7 CEG35994.1 - 1.7e-15 56.9 2.3 2.5e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 G-patch domain AIP3 PF03915.13 CEG35994.1 - 0.013 14.6 0.1 0.013 14.6 0.1 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 DUF3155 PF11352.8 CEG35996.1 - 0.024 15.1 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) PCI PF01399.27 CEG35997.1 - 3.2e-13 50.1 0.1 8.1e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 CEG35997.1 - 0.0019 17.9 0.4 0.0033 17.2 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 CSN4_RPN5_eIF3a PF18420.1 CEG35997.1 - 0.0025 18.0 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain zf-CCHC_4 PF14392.6 CEG35998.1 - 1.7e-05 24.5 17.8 0.44 10.3 0.3 4.4 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC PF00098.23 CEG35998.1 - 0.0049 16.9 30.2 0.011 15.8 3.5 4.2 4 0 0 4 4 4 3 Zinc knuckle SPATIAL PF15256.6 CEG35998.1 - 0.71 10.2 4.3 1.9 8.8 4.3 1.7 1 1 0 1 1 1 0 SPATIAL LSM PF01423.22 CEG35999.1 - 2.8e-19 68.6 0.1 3.1e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF3689 PF12463.8 CEG36001.1 - 3e-106 355.3 0.9 5e-106 354.5 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Il2rg PF15874.5 CEG36001.1 - 0.15 12.4 0.1 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Putative Interleukin 2 receptor, gamma chain WD40 PF00400.32 CEG36002.1 - 2e-15 56.9 1.4 0.00029 21.6 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36002.1 - 3.7e-06 27.1 0.0 0.56 10.5 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CEG36002.1 - 0.15 12.1 0.0 37 4.4 0.0 3.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CEG36002.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain DUF4064 PF13273.6 CEG36005.1 - 0.0019 18.4 0.1 0.0041 17.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) F5_F8_type_C PF00754.25 CEG36006.1 - 9.3e-07 29.0 0.3 1.4e-06 28.5 0.3 1.2 1 0 0 1 1 1 1 F5/8 type C domain FAM184 PF15665.5 CEG36007.1 - 5.3e-18 65.6 38.1 5.3e-18 65.6 38.1 9.1 1 1 7 8 8 8 3 Family with sequence similarity 184, A and B DUF2746 PF10874.8 CEG36007.1 - 0.016 15.6 1.2 0.49 10.8 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) HIG_1_N PF04588.13 CEG36009.1 - 0.21 11.8 1.2 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Hypoxia induced protein conserved region WD40 PF00400.32 CEG36011.1 - 0.00015 22.5 26.9 0.0011 19.7 0.9 8.8 11 0 0 11 11 11 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36011.1 - 0.078 13.3 0.8 2.6 8.4 0.1 3.8 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Kazal_2 PF07648.15 CEG36012.1 - 0.0031 17.6 0.1 0.0046 17.0 0.1 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CEG36013.1 - 5e-05 23.3 1.3 8.5e-05 22.6 0.2 1.9 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG36013.1 - 0.00019 21.4 0.7 0.00033 20.6 0.7 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain CPSF73-100_C PF11718.8 CEG36013.1 - 0.024 14.2 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Kazal_1 PF00050.21 CEG36014.1 - 1.4e-07 31.4 1.1 2.5e-07 30.6 1.1 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CEG36014.1 - 8e-06 25.9 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain ProRS-C_1 PF09180.11 CEG36015.1 - 2.7e-20 72.4 1.4 7.7e-20 70.9 1.4 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 CEG36015.1 - 4.3e-20 72.0 0.2 7.9e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 CEG36015.1 - 5.4e-18 65.6 0.0 9.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEG36015.1 - 1.6e-17 63.4 0.0 1.2e-16 60.6 0.0 2.4 3 0 0 3 3 3 1 Anticodon binding domain Acyl-CoA_dh_1 PF00441.24 CEG36017.1 - 4.4e-50 169.8 3.5 6.7e-50 169.2 3.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG36017.1 - 8.2e-26 90.9 0.1 2.3e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEG36017.1 - 2.3e-25 88.6 0.1 4.4e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG36017.1 - 3.7e-20 72.6 1.6 6.5e-20 71.8 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CEG36017.1 - 0.0024 17.6 0.1 0.0088 15.7 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal IFP_35_N PF07334.13 CEG36017.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BK_channel_a PF03493.18 CEG36019.1 - 2.3e-19 69.4 0.0 4.1e-18 65.4 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 CEG36019.1 - 1.5e-06 28.4 0.0 0.014 15.6 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans_2 PF07885.16 CEG36019.1 - 0.73 9.8 6.1 0.12 12.4 1.2 2.3 2 0 0 2 2 2 0 Ion channel NAD_binding_10 PF13460.6 CEG36023.1 - 6.6e-13 49.0 0.0 8.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEG36023.1 - 1.1e-10 41.5 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 CEG36023.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 CEG36023.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FYVE PF01363.21 CEG36024.1 - 1.5e-10 41.1 10.9 6.4e-10 39.0 10.9 2.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG36024.1 - 0.0014 18.9 8.0 0.0064 16.7 8.0 2.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 CEG36024.1 - 0.046 13.7 5.0 0.17 12.0 5.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CEG36024.1 - 0.11 12.4 11.8 0.31 11.1 11.8 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CEG36024.1 - 0.85 9.5 10.0 2.8 7.9 10.0 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG36024.1 - 1.6 9.0 9.9 3 8.1 7.2 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING HSF_DNA-bind PF00447.17 CEG36025.1 - 6.3e-22 78.0 1.1 8.2e-22 77.6 1.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding HIGH_NTase1 PF05636.11 CEG36025.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Phosphodiest PF01663.22 CEG36027.1 - 2.2e-09 37.4 0.3 3.2e-09 36.9 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CEG36027.1 - 0.0086 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 CEG36027.1 - 0.016 15.3 0.3 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 PglZ domain Sulfatase PF00884.23 CEG36027.1 - 0.017 14.5 0.1 0.044 13.2 0.0 1.7 2 0 0 2 2 2 0 Sulfatase LRR_8 PF13855.6 CEG36028.1 - 5.8e-12 45.2 16.9 4.7e-05 23.1 0.9 4.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CEG36028.1 - 2e-10 40.7 20.7 7.4e-05 23.0 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG36028.1 - 4.4e-09 36.1 6.0 4.9e-09 35.9 4.0 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CEG36028.1 - 0.27 11.4 20.9 4.4 7.6 0.7 7.0 7 1 1 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 CEG36028.1 - 0.6 10.9 12.6 25 5.9 0.4 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat UCH PF00443.29 CEG36029.1 - 4.4e-44 150.9 0.0 1.1e-43 149.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG36029.1 - 3.7e-15 56.3 1.1 1.4e-11 44.6 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG36029.1 - 0.00042 20.0 0.1 0.0012 18.5 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family zf-PARP PF00645.18 CEG36030.1 - 2.6e-06 28.2 0.1 3.8e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MOZ_SAS PF01853.18 CEG36031.1 - 3.2e-82 274.5 0.5 4.5e-82 274.1 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEG36031.1 - 2.2e-18 65.6 1.0 5.5e-18 64.3 1.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CEG36031.1 - 1.5e-13 50.4 0.7 3.7e-13 49.1 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain FCP1_C PF09309.10 CEG36031.1 - 0.12 12.3 12.3 0.15 11.9 10.8 1.8 3 0 0 3 3 3 0 FCP1, C-terminal UPF0560 PF10577.9 CEG36031.1 - 4.7 5.6 7.5 23 3.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF3712 PF12505.8 CEG36032.1 - 3.2e-30 105.0 8.1 1.1e-11 45.0 0.1 5.1 5 0 0 5 5 5 4 Protein of unknown function (DUF3712) WD40 PF00400.32 CEG36033.1 - 1.8e-39 133.0 19.6 2.5e-08 34.4 1.6 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CEG36033.1 - 2.3e-05 23.3 1.8 0.14 10.9 0.3 3.1 2 1 0 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 CEG36033.1 - 0.0011 19.2 2.4 3.1 8.2 0.4 4.4 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MRJP PF03022.16 CEG36033.1 - 0.016 14.6 0.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Major royal jelly protein WD40_like PF17005.5 CEG36033.1 - 0.03 13.6 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain DUF963 PF06131.11 CEG36033.1 - 0.17 11.4 0.4 0.4 10.1 0.4 1.7 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) SAP PF02037.27 CEG36034.1 - 1.7e-11 43.6 0.5 1.7e-11 43.6 0.5 2.8 3 0 0 3 3 3 1 SAP domain Tho1_MOS11_C PF18592.1 CEG36034.1 - 8.6e-05 22.3 16.6 0.0012 18.6 4.1 5.5 3 2 3 6 6 6 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 CEG36034.1 - 0.0029 17.3 0.1 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 HeH/LEM domain Myosin_head PF00063.21 CEG36035.1 - 4.6e-197 656.4 0.0 5.8e-197 656.0 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CEG36035.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Myosin_N PF02736.19 CEG36035.1 - 0.069 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CEG36035.1 - 0.094 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.17 CEG36037.1 - 2e-24 86.0 0.8 5.2e-24 84.7 0.8 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding ATG16 PF08614.11 CEG36037.1 - 0.0062 16.8 3.4 0.0062 16.8 3.4 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 CEG36037.1 - 0.021 14.9 2.9 0.021 14.9 2.9 2.5 2 1 1 3 3 3 0 bZIP transcription factor SlyX PF04102.12 CEG36037.1 - 0.44 11.2 3.1 1.7 9.3 3.1 2.0 1 0 0 1 1 1 0 SlyX JIP_LZII PF16471.5 CEG36037.1 - 3.9 7.7 7.1 3.8 7.8 1.0 3.3 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 CEG36037.1 - 7.6 6.8 9.1 0.27 11.5 2.6 1.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 CEG36037.1 - 9 6.7 7.8 1 9.7 3.1 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain GAF PF01590.26 CEG36038.1 - 9.4e-35 120.1 0.0 1.9e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 CEG36038.1 - 8.6e-24 84.4 0.0 1.2e-14 54.8 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 CEG36038.1 - 6.9e-12 45.8 0.0 7.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 GAF domain RIIa PF02197.17 CEG36038.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF2853 PF11015.8 CEG36038.1 - 0.031 14.9 0.0 0.078 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Transketolase_N PF00456.21 CEG36038.1 - 0.13 11.1 0.0 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain dCache_1 PF02743.18 CEG36038.1 - 0.16 11.7 0.1 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Cache domain Anoctamin PF04547.12 CEG36039.1 - 9.5e-51 173.0 21.9 1.3e-50 172.6 21.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ZYG-11_interact PF05884.12 CEG36040.1 - 0.024 14.0 0.8 0.043 13.2 0.5 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 Retrotran_gag_2 PF14223.6 CEG36046.1 - 0.055 13.1 0.8 0.55 9.9 0.8 2.0 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type HECT PF00632.25 CEG36049.1 - 2.6e-78 263.6 0.0 3.7e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps36-NZF-N PF16988.5 CEG36049.1 - 0.12 11.8 3.1 0.56 9.6 3.1 2.0 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 CEG36049.1 - 0.19 11.0 6.1 0.073 12.4 3.0 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DMRL_synthase PF00885.19 CEG36050.1 - 2.2e-59 199.3 0.3 2.9e-59 199.0 0.3 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DnaJ PF00226.31 CEG36051.1 - 1.2e-16 60.6 0.3 4.2e-16 58.8 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CEG36051.1 - 5.9e-11 41.7 10.5 1.7e-06 27.6 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36051.1 - 4.5e-10 39.0 7.8 2e-08 33.8 0.8 2.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 CEG36051.1 - 5.3e-09 35.5 15.2 6.6e-05 22.7 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36051.1 - 2.4e-07 30.6 0.6 0.00014 22.0 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36051.1 - 3.8e-06 26.7 5.7 0.027 14.7 0.1 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG36051.1 - 3e-05 24.5 10.5 0.033 15.0 0.1 4.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36051.1 - 0.0069 16.5 1.9 0.26 11.4 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG36051.1 - 0.013 16.1 0.7 0.013 16.1 0.7 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36051.1 - 0.015 15.6 6.8 0.14 12.5 0.9 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36051.1 - 0.079 13.5 0.8 0.079 13.5 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG36051.1 - 0.16 12.0 1.1 0.79 9.9 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG36051.1 - 0.44 10.6 4.2 56 3.9 0.2 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PAS_3 PF08447.12 CEG36051.1 - 0.57 10.5 2.9 0.89 9.9 0.1 2.5 2 0 0 2 2 2 0 PAS fold TPR_6 PF13174.6 CEG36051.1 - 1.9 9.3 8.7 4.9 8.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ART-PolyVal PF18760.1 CEG36051.1 - 7.6 7.6 9.2 6.7 7.7 1.0 2.7 2 0 0 2 2 2 0 ADP-Ribosyltransferase in polyvalent proteins Ku PF02735.16 CEG36053.1 - 1.1e-44 152.6 0.2 2e-44 151.7 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CEG36053.1 - 7e-25 87.5 1.3 2.2e-23 82.7 0.2 2.5 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 CEG36053.1 - 1.3e-14 54.5 0.6 4.2e-14 52.8 0.6 1.9 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 CEG36053.1 - 4.5e-08 33.7 0.9 5.2e-06 27.1 0.2 3.7 2 2 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 CEG36053.1 - 0.00031 21.0 0.7 0.001 19.4 0.7 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 CEG36053.1 - 0.017 15.8 0.0 0.4 11.4 0.0 3.0 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm WGG PF10273.9 CEG36054.1 - 2.8e-18 66.3 0.0 5.8e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RhoGEF PF00621.20 CEG36055.1 - 2.2e-66 223.6 0.4 6e-35 121.1 0.0 3.5 3 1 0 3 3 3 2 RhoGEF domain PH PF00169.29 CEG36055.1 - 1.8e-21 76.6 0.7 2.9e-05 24.5 0.1 5.9 5 0 0 5 5 5 3 PH domain FYVE PF01363.21 CEG36055.1 - 6.8e-16 58.2 6.2 2.5e-15 56.4 6.2 2.0 1 0 0 1 1 1 1 FYVE zinc finger PH_13 PF16652.5 CEG36055.1 - 2.1e-05 24.4 6.4 0.00032 20.5 0.1 4.7 5 0 0 5 5 5 1 Pleckstrin homology domain PH_11 PF15413.6 CEG36055.1 - 0.031 14.7 5.6 5 7.6 0.0 5.4 5 0 0 5 5 5 0 Pleckstrin homology domain FYVE_2 PF02318.16 CEG36055.1 - 9.9 6.4 18.6 0.082 13.1 4.9 3.5 3 0 0 3 3 3 0 FYVE-type zinc finger DUF2672 PF10878.8 CEG36056.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) MMR_HSR1_Xtn PF16897.5 CEG36057.1 - 5.3e-43 145.4 0.4 1.3e-42 144.1 0.4 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CEG36057.1 - 1.6e-19 70.1 0.0 3.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CEG36057.1 - 6e-17 61.5 0.0 1.4e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CEG36057.1 - 6.4e-10 38.8 0.0 2.5e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CEG36057.1 - 0.00067 18.7 0.2 0.0035 16.4 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CEG36057.1 - 0.0016 18.5 0.4 0.44 10.6 0.0 2.7 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CEG36057.1 - 0.021 14.4 1.1 4.3 6.8 0.0 3.8 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 CEG36057.1 - 0.05 13.8 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 CEG36058.1 - 5.1e-33 113.5 4.0 5.4e-08 33.3 0.1 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) RasGEF PF00617.19 CEG36058.1 - 1.5e-30 106.7 0.0 6.4e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain Ank_5 PF13857.6 CEG36058.1 - 1.1e-22 79.8 10.1 1.4e-05 25.3 0.0 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG36058.1 - 4.1e-22 78.3 3.7 6.2e-06 26.7 0.1 6.3 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CEG36058.1 - 8.8e-22 76.5 5.0 0.0075 16.7 0.0 9.3 8 1 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 CEG36058.1 - 8.5e-21 71.8 2.9 0.098 13.3 0.0 8.6 8 0 0 8 8 8 5 Ankyrin repeat PH PF00169.29 CEG36058.1 - 8.7e-09 35.8 0.0 2.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 PH domain VPS9 PF02204.18 CEG36058.1 - 7.1e-07 29.4 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH_8 PF15409.6 CEG36058.1 - 2.1e-06 27.9 0.1 0.015 15.6 0.0 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain FYVE PF01363.21 CEG36059.1 - 0.039 14.1 6.1 0.067 13.3 6.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-AN1 PF01428.16 CEG36059.1 - 2 8.7 10.0 0.57 10.4 6.9 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.21 CEG36059.1 - 4.3 7.6 11.0 9.3 6.6 7.8 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain YrhK PF14145.6 CEG36060.1 - 4e-17 61.8 8.3 5e-17 61.5 8.3 1.1 1 0 0 1 1 1 1 YrhK-like protein Saf_2TM PF18303.1 CEG36060.1 - 0.25 10.9 3.4 1.4 8.5 0.3 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4874 PF16173.5 CEG36061.1 - 0.033 13.9 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Mannosyl_trans2 PF04188.13 CEG36062.1 - 1.2e-31 110.5 8.0 1.6e-31 110.1 8.0 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) PHD PF00628.29 CEG36063.1 - 4.7e-16 58.4 28.3 1.6e-09 37.5 10.2 2.7 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 CEG36063.1 - 0.00021 20.7 22.4 0.0021 17.6 4.6 2.9 3 0 0 3 3 3 2 PHD-finger zf-CSL PF05207.13 CEG36063.1 - 0.045 13.5 15.6 0.021 14.6 4.3 2.9 2 0 0 2 2 2 0 CSL zinc finger PHD_4 PF16866.5 CEG36063.1 - 0.084 13.0 24.3 1.3 9.2 7.8 3.0 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 CEG36063.1 - 1.1 9.2 19.0 0.24 11.3 3.4 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GTP_EFTU PF00009.27 CEG36064.1 - 2.7e-36 125.0 1.1 8.2e-35 120.1 1.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEG36064.1 - 3.7e-22 78.4 0.7 1.1e-21 77.0 0.2 2.1 2 0 0 2 2 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CEG36064.1 - 1.8e-10 40.9 0.1 5.7e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG36064.1 - 2e-05 24.6 0.5 0.028 14.3 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEG36064.1 - 0.002 17.6 0.1 0.002 17.6 0.1 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CEG36064.1 - 0.0032 17.2 0.1 0.064 13.0 0.1 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CEG36064.1 - 0.009 16.1 0.9 0.13 12.4 0.0 2.6 2 1 1 3 3 3 1 Dynamin family Ras PF00071.22 CEG36064.1 - 0.017 14.7 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 CEG36064.1 - 0.018 14.5 0.2 0.11 12.0 0.2 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B IF2_N PF04760.15 CEG36064.1 - 0.027 14.3 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GntR PF00392.21 CEG36064.1 - 0.03 14.0 0.1 0.073 12.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family ABC_tran PF00005.27 CEG36066.1 - 6.9e-53 178.8 0.1 4.5e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CEG36066.1 - 4.1e-52 177.4 64.0 8.3e-32 110.6 26.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CEG36066.1 - 7.5e-18 65.4 2.7 4.7e-07 29.9 0.0 4.0 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG36066.1 - 1.6e-05 24.5 0.0 0.13 11.7 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CEG36066.1 - 4.4e-05 23.3 0.6 0.18 11.5 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CEG36066.1 - 0.00094 19.7 2.9 0.0095 16.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.6 CEG36066.1 - 0.0012 19.5 0.6 2.3 9.0 0.0 3.7 5 0 0 5 5 3 1 Domain of unknown function (DUF4162) ABC2_membrane_5 PF13346.6 CEG36066.1 - 0.0028 17.2 18.0 0.0028 17.2 18.0 3.6 3 1 1 4 4 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CEG36066.1 - 0.0077 16.2 0.5 0.028 14.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CEG36066.1 - 0.01 15.6 0.2 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEG36066.1 - 0.011 15.5 1.7 0.047 13.4 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CEG36066.1 - 0.049 13.9 0.0 20 5.5 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nre_C PF04895.12 CEG36066.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal Nre, C-terminal AAA_22 PF13401.6 CEG36066.1 - 0.11 12.8 0.4 3.9 7.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain Ubiq_cyt_C_chap PF03981.12 CEG36066.1 - 0.14 12.3 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone MMR_HSR1 PF01926.23 CEG36066.1 - 0.17 12.0 0.5 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2813 PF11398.8 CEG36066.1 - 0.21 10.8 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) SRP54 PF00448.22 CEG36066.1 - 0.24 11.0 3.3 4.8 6.7 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 CEG36066.1 - 0.25 11.1 3.1 7.5 6.3 0.2 2.9 3 0 0 3 3 3 0 MukB N-terminal AAA PF00004.29 CEG36066.1 - 0.57 10.6 3.0 52 4.3 0.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEG36066.1 - 0.8 9.4 2.5 11 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CEG36066.1 - 1.1 8.5 46.5 4.5 6.5 0.1 4.1 3 2 0 3 3 3 0 ABC-2 family transporter protein Orn_Arg_deC_N PF02784.16 CEG36067.1 - 8.9e-40 136.6 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEG36067.1 - 2.6e-20 72.5 0.0 2.8e-20 72.3 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RVT_2 PF07727.14 CEG36069.1 - 3.7e-35 121.7 0.5 5.3e-35 121.2 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG36069.1 - 0.00071 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.20 CEG36070.1 - 5e-144 480.8 8.2 6.2e-144 480.4 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG36070.1 - 1.5e-13 50.3 0.0 2.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Big_3 PF07523.12 CEG36070.1 - 0.0011 19.2 0.1 0.0032 17.7 0.1 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) StbA PF06406.11 CEG36070.1 - 0.0033 16.7 0.6 0.12 11.6 0.1 2.4 2 1 0 2 2 2 1 StbA protein DUF2190 PF09956.9 CEG36070.1 - 0.0042 17.6 1.7 0.045 14.2 0.8 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2190) TPP_enzyme_N PF02776.18 CEG36070.1 - 0.017 14.7 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FtsA PF14450.6 CEG36070.1 - 0.36 11.3 6.7 17 5.9 0.7 3.8 3 1 0 3 3 3 0 Cell division protein FtsA Yip1 PF04893.17 CEG36071.1 - 3.3e-07 30.2 10.4 4.2e-07 29.8 10.4 1.2 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 CEG36071.1 - 0.013 15.1 7.3 0.29 10.6 7.3 2.0 1 1 0 1 1 1 0 YIF1 Ion_trans PF00520.31 CEG36072.1 - 2.2e-05 23.8 7.7 2.2e-05 23.8 7.7 1.6 2 0 0 2 2 2 1 Ion transport protein Glyoxalase PF00903.25 CEG36073.1 - 0.027 14.7 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-UBR PF02207.20 CEG36074.1 - 8.5e-18 64.3 16.3 8.5e-18 64.3 16.3 3.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) KH_1 PF00013.29 CEG36075.1 - 8.3e-76 249.8 22.2 2e-10 40.4 0.0 11.0 11 0 0 11 11 11 9 KH domain SLS PF14611.6 CEG36075.1 - 2.6e-12 47.0 25.9 1.5e-05 25.0 2.8 8.1 3 2 5 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CEG36075.1 - 1.4e-11 44.1 4.6 0.69 9.8 0.0 8.0 7 1 0 7 7 7 4 KH domain KH_2 PF07650.17 CEG36075.1 - 3.2e-11 42.9 21.7 0.18 11.7 0.4 8.8 6 2 1 8 8 8 5 KH domain KH_5 PF13184.6 CEG36075.1 - 6.4e-06 26.2 12.1 4.4 7.5 0.5 7.3 7 0 0 7 7 7 2 NusA-like KH domain KAsynt_C_assoc PF16197.5 CEG36075.1 - 0.91 10.0 4.4 1.5 9.3 0.1 3.6 4 0 0 4 4 4 0 Ketoacyl-synthetase C-terminal extension Secretin_N PF03958.17 CEG36075.1 - 4.2 7.8 5.4 27 5.3 0.3 4.4 4 1 0 4 4 4 0 Bacterial type II/III secretion system short domain Kinesin PF00225.23 CEG36076.1 - 2.3e-18 66.2 0.0 5.6e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG36076.1 - 1.1e-05 25.4 0.4 3.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DUF1623 PF07785.11 CEG36076.1 - 0.08 13.1 1.5 0.38 10.9 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) TMF_DNA_bd PF12329.8 CEG36076.1 - 0.12 12.4 4.3 0.47 10.5 4.3 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 CEG36076.1 - 0.43 10.2 14.6 1.2 8.8 14.6 1.8 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 CEG36076.1 - 2 8.6 17.3 0.19 11.9 11.9 2.0 2 0 0 2 2 2 0 Tropomyosin like Cep57_CLD_2 PF14197.6 CEG36076.1 - 5 7.3 9.1 1.3 9.1 0.1 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 CEG36076.1 - 5 7.5 17.6 0.29 11.5 11.3 2.2 3 0 0 3 3 3 0 Fez1 NBP1 PF08537.10 CEG36076.1 - 8.3 5.7 11.6 0.43 10.0 5.3 2.0 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 Agenet PF05641.12 CEG36077.1 - 0.00034 21.0 0.3 0.00091 19.6 0.0 1.8 2 0 0 2 2 2 1 Agenet domain Tudor_3 PF18115.1 CEG36077.1 - 0.003 17.4 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 CEG36077.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 RRP7 PF12923.7 CEG36077.1 - 0.026 14.6 1.1 0.026 14.6 1.1 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain HemY_N PF07219.13 CEG36077.1 - 0.11 12.7 0.8 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus RAP1 PF07218.11 CEG36077.1 - 9.6 4.3 7.8 4.7 5.4 0.2 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2 PF00096.26 CEG36081.1 - 1.7e-17 62.8 48.0 2.5e-05 24.5 0.8 7.6 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEG36081.1 - 5e-15 55.1 47.2 1.7e-05 25.0 0.3 7.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEG36081.1 - 7.3e-13 48.2 45.8 0.0035 18.0 1.0 7.8 7 0 0 7 7 7 5 C2H2-type zinc finger Exo_endo_phos PF03372.23 CEG36081.1 - 2.2e-10 40.5 0.0 7e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-Di19 PF05605.12 CEG36081.1 - 0.00084 19.6 1.4 0.00084 19.6 1.4 4.8 4 1 1 5 5 5 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CEG36081.1 - 0.00086 19.6 17.2 2 8.8 0.3 5.1 4 1 1 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CEG36081.1 - 0.0018 18.7 21.3 1.4 9.4 0.6 5.5 4 2 0 4 4 4 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CEG36081.1 - 0.035 14.1 34.4 0.074 13.1 0.7 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEG36081.1 - 0.13 12.6 0.3 0.13 12.6 0.3 5.9 6 1 0 6 6 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 CEG36081.1 - 0.31 10.9 3.3 1.4 8.8 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-FPG_IleRS PF06827.14 CEG36081.1 - 1.3 9.0 5.9 0.26 11.2 0.2 2.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 CEG36081.1 - 2.2 7.9 10.9 6.6 6.4 0.1 3.8 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 CEG36081.1 - 4.7 7.1 9.3 2.4 8.1 0.2 3.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-C2H2_aberr PF17017.5 CEG36081.1 - 6 7.0 12.7 0.4 10.8 0.1 3.7 3 1 1 4 4 4 0 Aberrant zinc-finger Kazal_1 PF00050.21 CEG36082.1 - 2.6e-30 104.2 24.9 1e-09 38.3 6.2 3.6 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CEG36082.1 - 3.7e-29 100.6 29.1 1.2e-10 41.3 6.2 3.6 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain Myf5 PF12232.8 CEG36082.1 - 0.045 14.5 4.6 0.045 14.5 4.6 3.1 2 1 1 3 3 3 0 Myogenic determination factor 5 PDZ PF00595.24 CEG36085.1 - 1.9e-21 76.2 0.0 0.00032 21.0 0.0 5.3 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 CEG36085.1 - 2.1e-18 65.9 0.0 0.0095 15.8 0.0 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 CEG36085.1 - 1.8e-07 31.4 0.2 0.44 10.9 0.0 4.3 4 0 0 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 CEG36085.1 - 4.7e-05 23.3 0.0 7.4 6.6 0.0 5.0 5 0 0 5 5 5 1 Tricorn protease PDZ domain SPATA9 PF15824.5 CEG36085.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 TTC5_OB PF16669.5 CEG36087.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain LCAT PF02450.15 CEG36089.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase rve PF00665.26 CEG36090.1 - 0.011 16.0 0.2 0.034 14.3 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DDE_3 PF13358.6 CEG36090.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease SDA1 PF05285.12 CEG36090.1 - 0.33 10.3 13.3 0.43 10.0 13.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CEG36090.1 - 2.1 6.5 12.2 2.8 6.1 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family PHD PF00628.29 CEG36091.1 - 1.4e-11 44.1 12.1 1.4e-11 44.1 12.1 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CEG36091.1 - 0.0023 17.8 4.0 0.0023 17.8 4.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C2 PF00168.30 CEG36092.1 - 6.3e-100 328.4 0.0 3.8e-15 56.0 0.0 8.8 9 0 0 9 9 9 8 C2 domain FerI PF08151.12 CEG36092.1 - 0.00046 20.2 0.0 0.002 18.2 0.0 2.1 1 0 0 1 1 1 1 FerI (NUC094) domain Ferlin_C PF16165.5 CEG36092.1 - 0.024 14.6 0.3 0.024 14.6 0.3 3.8 4 1 0 4 4 4 0 Ferlin C-terminus IQ PF00612.27 CEG36092.1 - 0.8 9.7 13.0 4.7 7.3 0.5 3.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif Aph-1 PF06105.12 CEG36094.1 - 1.4e-45 155.5 17.1 1.7e-45 155.3 17.1 1.0 1 0 0 1 1 1 1 Aph-1 protein DUF4181 PF13789.6 CEG36094.1 - 2.9 8.2 6.6 0.49 10.7 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) EPSP_synthase PF00275.20 CEG36095.1 - 5.7e-123 410.7 0.1 8.4e-123 410.1 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CEG36095.1 - 5.1e-95 317.6 0.2 1.1e-94 316.5 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CEG36095.1 - 3e-42 145.4 0.0 5.6e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CEG36095.1 - 2.2e-27 96.1 0.0 1.1e-25 90.6 0.0 3.4 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 CEG36095.1 - 5.7e-18 64.9 0.0 1.6e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 CEG36095.1 - 2.3e-11 43.9 0.0 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 CEG36095.1 - 2.1e-08 34.3 0.0 4.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 CEG36095.1 - 0.00032 20.4 0.9 0.00062 19.5 0.1 2.0 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH PF00465.19 CEG36095.1 - 0.00075 18.4 0.1 0.0018 17.1 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 CEG36095.1 - 0.023 15.1 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CEG36095.1 - 0.028 14.6 0.0 0.099 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CEG36095.1 - 0.03 13.5 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEG36095.1 - 0.07 13.7 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CEG36095.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.17 CEG36095.1 - 0.11 13.1 0.1 0.32 11.6 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent tRNA-synt_1 PF00133.22 CEG36096.1 - 2.6e-40 138.3 0.0 3.3e-26 91.7 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CEG36096.1 - 1.3e-18 67.0 0.0 7e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEG36096.1 - 2.4e-14 53.6 0.0 5.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CEG36096.1 - 3.5e-08 33.2 0.0 9e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CEG36096.1 - 0.081 11.8 0.0 6.9 5.5 0.0 3.1 2 1 1 3 3 3 0 tRNA synthetases class I (K) IMS_HHH PF11798.8 CEG36096.1 - 0.11 12.8 0.0 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 IMS family HHH motif eIF2_C PF09173.11 CEG36097.1 - 2.7e-37 126.9 0.9 7.9e-37 125.4 0.9 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CEG36097.1 - 9.9e-24 83.9 1.0 6.1e-23 81.4 1.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEG36097.1 - 1.1e-13 51.3 0.8 1.1e-12 48.1 0.9 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG36097.1 - 0.0029 17.6 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG36097.1 - 0.026 14.4 1.2 0.46 10.4 0.2 2.5 2 0 0 2 2 2 0 RsgA GTPase DUF1098 PF06497.11 CEG36097.1 - 0.036 14.5 0.3 0.14 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) WD40 PF00400.32 CEG36098.1 - 4.9e-16 58.8 12.2 4.3e-05 24.2 0.1 9.2 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36098.1 - 1.7e-07 31.4 0.0 0.23 11.8 0.0 6.3 6 1 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain KASH_CCD PF14662.6 CEG36098.1 - 0.00034 20.5 19.3 0.00034 20.5 19.3 4.5 3 2 2 5 5 5 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CEG36098.1 - 0.00079 19.5 12.4 0.00079 19.5 12.4 5.9 2 2 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 CEG36098.1 - 0.005 16.7 2.6 0.005 16.7 2.6 7.0 6 1 2 8 8 8 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Cytochrom_D1 PF02239.16 CEG36098.1 - 0.051 12.1 0.5 2.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Rad21_Rec8_N PF04825.13 CEG36098.1 - 0.12 12.6 1.2 1.3 9.2 0.2 3.1 2 1 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein LSM PF01423.22 CEG36099.1 - 7.8e-08 31.9 0.4 1.2e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEG36099.1 - 4.1e-06 26.8 0.1 6.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HTH_Tnp_Tc5 PF03221.16 CEG36100.1 - 4.3e-10 39.5 0.1 1.1e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.6 CEG36100.1 - 0.00014 21.4 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CEG36100.1 - 0.00099 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_32 PF13565.6 CEG36100.1 - 0.012 16.2 0.2 9 7.0 0.0 2.6 1 1 1 2 2 2 0 Homeodomain-like domain Augurin PF15187.6 CEG36104.1 - 0.044 14.0 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 LRR_4 PF12799.7 CEG36105.1 - 2.8e-08 33.9 6.9 0.0014 19.0 0.4 3.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) NRDE-2 PF08424.10 CEG36105.1 - 9.2e-07 28.3 1.9 3e-06 26.6 1.9 1.9 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference LRR_8 PF13855.6 CEG36105.1 - 6.4e-06 25.8 9.2 0.00032 20.4 3.9 3.3 2 1 0 2 2 2 2 Leucine rich repeat zf-C3H1 PF10650.9 CEG36105.1 - 0.00059 19.5 0.9 0.0014 18.3 0.9 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain Rop PF01815.16 CEG36105.1 - 0.012 15.4 0.0 0.047 13.6 0.0 2.0 1 0 0 1 1 1 0 Rop protein zf-NF-X1 PF01422.17 CEG36105.1 - 0.021 14.8 1.0 0.052 13.6 1.0 1.6 1 0 0 1 1 1 0 NF-X1 type zinc finger LRR_1 PF00560.33 CEG36105.1 - 0.54 11.0 2.8 1.8e+02 3.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat Elong_Iki1 PF10483.9 CEG36108.1 - 0.04 13.4 0.0 0.048 13.2 0.0 1.0 1 0 0 1 1 1 0 Elongator subunit Iki1 Clat_adaptor_s PF01217.20 CEG36112.1 - 1.1e-52 177.8 4.0 1.2e-52 177.6 4.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BolA PF01722.18 CEG36113.1 - 6e-30 103.3 0.8 8.9e-30 102.8 0.8 1.3 1 0 0 1 1 1 1 BolA-like protein DFP PF04127.15 CEG36114.1 - 2.3e-18 66.7 0.0 1.2e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Spindle_Spc25 PF08234.12 CEG36115.1 - 1.2e-18 67.1 1.6 1.9e-18 66.4 0.6 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 MMR1 PF08505.10 CEG36115.1 - 0.34 11.2 8.2 0.51 10.6 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Tmemb_185A PF10269.9 CEG36118.1 - 0.0012 18.5 26.3 0.014 15.1 26.6 2.4 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein AC_N PF16214.5 CEG36118.1 - 0.07 12.2 5.4 0.16 11.1 5.4 1.5 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PIG-P PF08510.12 CEG36118.1 - 0.39 10.6 9.7 3.8 7.4 3.9 2.9 2 0 0 2 2 2 0 PIG-P DUF4239 PF14023.6 CEG36118.1 - 4.7 6.9 6.7 1.1 9.0 1.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) DEAD PF00270.29 CEG36119.1 - 2.3e-47 161.0 0.0 6.6e-47 159.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CEG36119.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEG36119.1 - 7.9e-05 23.0 0.2 0.0023 18.3 0.1 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CEG36119.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.9 2 1 1 3 3 3 1 SWI2/SNF2 ATPase CPSase_L_D3 PF02787.19 CEG36119.1 - 0.25 11.7 1.8 0.44 10.9 1.1 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RCC1 PF00415.18 CEG36120.1 - 2.3e-78 258.6 13.5 2.7e-14 53.5 0.0 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CEG36120.1 - 1.1e-58 199.2 0.1 2.6e-58 197.9 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 CEG36120.1 - 2.4e-36 122.8 34.0 1.2e-07 31.3 0.1 8.8 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 CEG36120.1 - 4.1e-19 68.9 0.0 1.4e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 CEG36120.1 - 6.4e-09 36.1 0.0 7.3e-08 32.7 0.0 2.6 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 CEG36120.1 - 0.00026 20.8 0.0 0.00099 19.0 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain Trypsin_2 PF13365.6 CEG36121.1 - 1.5e-16 61.7 0.1 2.4e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG36121.1 - 5.7e-06 26.3 1.1 0.00014 21.8 1.1 2.4 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.19 CEG36121.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 Folate_rec PF03024.14 CEG36126.1 - 1.1e-10 41.7 10.1 1.5e-10 41.2 10.1 1.2 1 0 0 1 1 1 1 Folate receptor family NDUF_B7 PF05676.13 CEG36127.1 - 6e-28 96.4 1.0 9e-28 95.8 1.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CEG36127.1 - 0.00021 21.2 0.2 0.00029 20.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CEG36127.1 - 0.088 13.1 1.9 0.34 11.2 1.2 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 AD PF09793.9 CEG36128.1 - 4.6e-25 87.6 0.0 6.7e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 CEG36128.1 - 4.6e-12 45.8 0.1 1e-10 41.4 0.1 2.1 1 1 0 1 1 1 1 Gemin6 protein LSM PF01423.22 CEG36128.1 - 0.016 14.9 0.1 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 LSM domain HSCB_C PF07743.13 CEG36128.1 - 0.039 14.5 0.4 0.072 13.6 0.4 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain LSM14 PF12701.7 CEG36128.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Scd6-like Sm domain Mad3_BUB1_I PF08311.12 CEG36129.1 - 2.3e-39 134.2 2.8 5.2e-39 133.0 2.8 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 YmaF PF12788.7 CEG36129.1 - 0.023 15.2 0.6 0.081 13.5 0.1 2.0 2 0 0 2 2 2 0 YmaF family His_Phos_1 PF00300.22 CEG36129.1 - 0.027 14.1 0.2 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HBS1_N PF08938.10 CEG36130.1 - 0.58 10.5 4.3 2.4 8.5 0.1 3.2 3 0 0 3 3 3 0 HBS1 N-terminus DUF4710 PF15828.5 CEG36130.1 - 1.8 8.7 8.8 23 5.2 5.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) Glycoprot_B_PH2 PF17417.2 CEG36133.1 - 0.01 16.1 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain Tyrosinase PF00264.20 CEG36135.1 - 1.7e-05 25.3 0.0 1.7e-05 25.3 0.0 4.1 3 2 0 3 3 3 1 Common central domain of tyrosinase Suppressor_P21 PF11479.8 CEG36141.1 - 0.037 14.2 0.1 0.053 13.7 0.1 1.3 1 1 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain RXLR_WY PF18634.1 CEG36142.1 - 0.00022 21.1 0.8 0.00041 20.2 0.8 1.5 1 0 0 1 1 1 1 RXLR phytopathogen effector protein WY-domain Snapin_Pallidin PF14712.6 CEG36142.1 - 0.056 13.9 9.5 1.4 9.4 3.8 2.6 2 1 1 3 3 3 0 Snapin/Pallidin DASH_Dad2 PF08654.10 CEG36142.1 - 0.059 13.8 0.7 0.059 13.8 0.7 1.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 Lzipper-MIP1 PF14389.6 CEG36142.1 - 1.1 9.6 6.1 1.3 9.4 3.4 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Hexapep_loop PF18776.1 CEG36145.1 - 1.1 9.0 3.1 0.57 9.9 0.3 1.9 2 0 0 2 2 2 0 Hexapeptide repeat including loop Adaptin_N PF01602.20 CEG36146.1 - 7.3e-84 282.2 4.5 1.1e-83 281.6 4.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CEG36146.1 - 4.4e-58 194.8 0.4 1.1e-57 193.5 0.1 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CEG36146.1 - 5e-50 169.1 0.0 1.2e-49 167.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 CEG36146.1 - 1e-08 35.5 4.5 0.053 13.9 0.0 5.8 4 2 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CEG36146.1 - 1.9e-08 34.5 2.7 1.1e-07 32.0 0.2 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 CEG36146.1 - 4.5e-05 23.5 0.0 0.00018 21.6 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 CEG36146.1 - 0.00035 20.6 0.3 1.7 9.1 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 CEG36146.1 - 0.13 12.4 0.1 2.3 8.4 0.1 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat GCP_C_terminal PF04130.13 CEG36146.1 - 0.16 11.4 1.3 0.23 10.9 0.2 1.8 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal Glyco_hydro_47 PF01532.20 CEG36147.1 - 1.9e-112 376.5 0.0 2.8e-112 376.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 CEG36147.1 - 6.7e-11 42.1 0.0 1.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PA domain PRKCSH PF07915.13 CEG36147.1 - 1.8e-09 38.5 0.0 8.7e-09 36.3 0.0 2.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CEG36147.1 - 1.9e-07 30.9 0.1 4.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Vma12 PF11712.8 CEG36148.1 - 1.7e-10 41.1 0.6 2.5e-10 40.5 0.6 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2615 PF11027.8 CEG36148.1 - 0.12 12.5 2.5 1.6 8.9 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2615) DUF4407 PF14362.6 CEG36148.1 - 9.5 5.5 11.4 0.22 10.8 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NEMP PF10225.9 CEG36149.1 - 5.9e-17 62.2 9.2 1.1e-08 35.1 0.1 2.4 2 0 0 2 2 2 2 NEMP family DUF2157 PF09925.9 CEG36149.1 - 0.46 10.3 14.1 1.1 9.1 8.0 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) C2 PF00168.30 CEG36152.1 - 6.3e-24 84.2 0.0 8.1e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 CEG36153.1 - 2.7e-23 82.2 0.0 4.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.11 CEG36153.1 - 3.3e-05 23.1 1.8 4e-05 22.8 1.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin F5_F8_type_C PF00754.25 CEG36153.1 - 0.024 14.8 0.2 0.066 13.3 0.1 1.7 2 0 0 2 2 2 0 F5/8 type C domain HSP70 PF00012.20 CEG36154.1 - 5e-65 219.8 4.1 6.1e-62 209.6 0.5 2.2 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 CEG36154.1 - 3.2e-10 39.4 11.5 5e-05 22.9 1.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36154.1 - 4.4e-09 35.8 12.5 0.0022 17.9 2.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36154.1 - 5.8e-06 26.1 8.1 0.025 14.8 0.9 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36154.1 - 2.7e-05 23.8 1.7 0.0087 15.7 1.4 2.7 2 0 0 2 2 2 1 TPR repeat MreB_Mbl PF06723.13 CEG36154.1 - 0.00016 20.6 4.3 0.00017 20.5 2.0 2.1 2 1 0 2 2 2 1 MreB/Mbl protein TPR_9 PF13371.6 CEG36154.1 - 0.00034 20.7 3.1 0.00034 20.7 3.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG36154.1 - 0.0013 19.3 8.8 0.0058 17.2 5.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36154.1 - 0.0019 18.5 4.5 0.0033 17.7 0.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat FAA_hydrolase PF01557.18 CEG36154.1 - 0.015 15.0 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family TPR_7 PF13176.6 CEG36154.1 - 0.023 14.7 2.9 2.2 8.5 1.5 3.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 CEG36154.1 - 0.032 13.2 0.6 0.059 12.4 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_19 PF14559.6 CEG36154.1 - 0.046 14.2 10.2 0.11 13.0 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CEG36154.1 - 0.054 13.6 3.7 0.089 12.9 0.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 CEG36154.1 - 0.3 11.8 5.4 7.8 7.4 1.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG36154.1 - 0.31 11.3 7.8 1 9.7 7.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CEG36154.1 - 0.38 11.3 3.9 2.1 8.9 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG36154.1 - 5.2 8.2 7.7 61 4.8 3.5 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat HNH PF01844.23 CEG36155.1 - 1.9e-06 27.9 3.4 6.4e-06 26.2 3.4 1.9 1 0 0 1 1 1 1 HNH endonuclease DUF5476 PF17570.2 CEG36155.1 - 0.049 14.0 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5476) HisK_N PF09385.10 CEG36155.1 - 0.055 13.4 0.2 0.26 11.2 0.0 2.0 1 1 1 2 2 2 0 Histidine kinase N terminal DnaG_DnaB_bind PF08278.11 CEG36155.1 - 0.087 13.4 1.6 0.2 12.2 1.1 1.8 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding TUDOR PF00567.24 CEG36155.1 - 0.089 12.8 0.0 0.3 11.1 0.0 1.9 1 1 0 1 1 1 0 Tudor domain Biopterin_H PF00351.21 CEG36156.1 - 2.7e-151 503.3 0.0 4.4e-151 502.6 0.0 1.3 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 CEG36156.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain CEP44 PF15007.6 CEG36157.1 - 0.0098 16.1 0.1 0.099 12.8 0.0 2.5 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 L27 PF02828.16 CEG36157.1 - 0.029 14.1 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 L27 domain FA_desaturase PF00487.24 CEG36157.1 - 0.031 14.1 0.4 0.059 13.2 0.4 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Thymidylate_kin PF02223.17 CEG36158.1 - 1.6e-47 161.6 0.0 1.9e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 CEG36158.1 - 0.00071 19.9 0.0 0.0015 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 CEG36158.1 - 0.06 13.4 0.0 0.26 11.4 0.0 1.9 2 1 0 2 2 2 0 Adenylate kinase DSPn PF14671.6 CEG36159.1 - 0.0024 18.4 0.3 0.44 11.0 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CEG36159.1 - 0.068 13.0 0.7 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Ank_2 PF12796.7 CEG36160.1 - 2e-41 140.5 12.9 1.5e-08 35.1 0.0 10.7 7 3 3 10 10 10 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG36160.1 - 1.5e-30 105.1 15.3 4.7e-05 23.9 0.1 11.7 10 2 2 12 12 12 6 Ankyrin repeats (many copies) zf-TRAF PF02176.18 CEG36160.1 - 3.8e-30 104.3 181.4 0.00013 22.6 5.4 17.9 6 5 12 18 18 18 15 TRAF-type zinc finger Ank_3 PF13606.6 CEG36160.1 - 1.4e-22 77.3 16.7 0.023 15.2 0.0 13.9 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 CEG36160.1 - 2.9e-19 68.6 9.6 0.29 11.6 0.0 12.2 11 1 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 CEG36160.1 - 8.4e-15 54.7 9.0 0.0049 17.1 0.0 8.2 7 3 3 10 10 10 5 Ankyrin repeats (many copies) RasGEF_N PF00618.20 CEG36160.1 - 0.041 14.1 1.9 0.26 11.6 1.9 2.4 1 0 0 1 1 1 0 RasGEF N-terminal motif DIPSY PF11763.8 CEG36160.1 - 0.051 13.8 1.1 0.43 10.8 0.4 2.9 2 0 0 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal PARP_reg PF02877.14 CEG36160.1 - 3.4 7.8 8.4 3.7 7.6 0.1 3.6 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain Gag_p19 PF02228.16 CEG36161.1 - 0.034 14.6 0.1 0.061 13.8 0.1 1.4 1 0 0 1 1 1 0 Major core protein p19 LPD38 PF18857.1 CEG36161.1 - 0.079 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Bestrophin PF01062.21 CEG36163.1 - 1.5e-19 70.5 3.0 1.9e-19 70.1 3.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel APG6 PF04111.12 CEG36164.1 - 3.6e-54 183.4 0.1 7.9e-54 182.3 0.1 1.6 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CEG36164.1 - 7.2e-21 75.1 3.0 7.2e-21 75.1 3.0 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region Activator_LAG-3 PF11498.8 CEG36164.1 - 1 8.3 15.9 2.1 7.3 15.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pkinase_Tyr PF07714.17 CEG36166.1 - 1.7e-37 129.1 0.0 7.5e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG36166.1 - 2.3e-37 128.8 0.0 1e-24 87.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.21 CEG36166.1 - 2.1e-06 27.7 0.0 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 CEG36166.1 - 0.0089 16.0 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG36166.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like CLLAC PF15675.5 CEG36167.1 - 3.8 7.1 11.2 0.41 10.3 2.4 3.2 2 1 0 2 2 2 0 CLLAC-motif containing domain Myb_DNA-binding PF00249.31 CEG36172.1 - 5.6e-31 106.5 3.5 8e-16 58.0 1.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG36172.1 - 1.6e-25 89.1 0.6 1.5e-16 60.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG36172.1 - 1.8e-08 34.2 0.4 0.00011 22.0 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEG36172.1 - 1.3e-05 25.2 0.6 0.051 13.8 0.0 2.4 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CEG36172.1 - 0.011 15.7 0.1 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 SLIDE Thymidylat_synt PF00303.19 CEG36173.1 - 1.4e-118 394.9 0.0 1.9e-118 394.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CEG36173.1 - 1.1e-38 132.4 0.0 2.9e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Dihydrofolate reductase EMP24_GP25L PF01105.24 CEG36176.1 - 5.8e-32 111.1 0.3 6.6e-32 110.9 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Baculo_ODV-E27 PF05314.11 CEG36176.1 - 0.013 14.7 0.3 0.019 14.1 0.3 1.2 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 ATP-grasp_3 PF02655.14 CEG36177.1 - 0.085 12.9 0.0 55 3.8 0.0 4.7 3 0 0 3 3 3 0 ATP-grasp domain DMT_YdcZ PF04657.13 CEG36177.1 - 4.9 7.4 7.7 11 6.3 0.1 4.6 5 0 0 5 5 5 0 Putative inner membrane exporter, YdcZ cwf18 PF08315.12 CEG36179.1 - 3.9e-19 69.7 8.6 3.9e-19 69.7 8.6 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor LMBR1 PF04791.16 CEG36179.1 - 1.1 8.1 2.5 1.2 8.0 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4633 PF15464.6 CEG36179.1 - 1.6 8.9 4.7 2 8.6 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4633) Cyclin_C_2 PF16899.5 CEG36180.1 - 2.5e-11 43.9 0.1 1.3e-10 41.6 0.1 2.2 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CEG36180.1 - 4.5e-06 26.4 0.1 8.6e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF885 PF05960.11 CEG36180.1 - 0.0084 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) TFIIB PF00382.19 CEG36180.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF4061 PF13270.6 CEG36180.1 - 0.63 10.4 7.2 7.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) PDGF_N PF04692.13 CEG36180.1 - 0.74 10.6 3.6 1.5 9.7 0.1 2.5 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Peptidase_C1 PF00112.23 CEG36181.1 - 6.9e-42 144.0 1.4 1.4e-41 143.0 1.4 1.5 2 0 0 2 2 2 1 Papain family cysteine protease PCMT PF01135.19 CEG36181.1 - 1.6e-35 122.8 0.0 3.8e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CEG36181.1 - 1e-09 38.4 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG36181.1 - 1.9e-06 28.5 0.0 4.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG36181.1 - 2.5e-06 28.0 0.0 7.9e-06 26.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CEG36181.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CEG36181.1 - 5.7e-05 22.6 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Drc1-Sld2 PF11719.8 CEG36181.1 - 0.00028 20.6 1.0 0.00035 20.2 0.2 1.6 2 0 0 2 2 2 1 DNA replication and checkpoint protein Methyltransf_23 PF13489.6 CEG36181.1 - 0.00049 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG36181.1 - 0.00052 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG36181.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CEG36181.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ish1 PF10281.9 CEG36181.1 - 0.0093 16.2 0.5 0.098 13.0 0.1 2.3 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Peptidase_C1_2 PF03051.15 CEG36181.1 - 0.027 13.3 1.3 0.15 10.8 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family UPF0179 PF03684.13 CEG36181.1 - 0.077 12.9 0.9 0.16 11.9 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) Methyltransf_32 PF13679.6 CEG36181.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 CEG36181.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase GPI-anchored PF10342.9 CEG36182.1 - 1.1 10.0 5.4 33 5.3 0.1 4.0 3 1 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5592 PF17332.2 CEG36183.1 - 0.083 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5592) Avidin PF01382.17 CEG36184.1 - 0.12 12.9 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Avidin family FYVE PF01363.21 CEG36185.1 - 2.2e-06 27.7 15.0 6.2e-06 26.3 15.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG36185.1 - 0.11 12.8 11.2 0.3 11.3 11.2 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Peptidase_S74 PF13884.6 CEG36187.1 - 0.0041 17.4 0.1 0.0068 16.7 0.1 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase MinC_C PF03775.16 CEG36188.1 - 0.048 13.7 0.1 0.094 12.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain GNVR PF13807.6 CEG36190.1 - 0.0062 16.4 0.1 0.052 13.5 0.1 2.3 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase VIT1 PF01988.19 CEG36190.1 - 0.59 10.0 1.2 0.9 9.4 0.3 1.7 2 0 0 2 2 2 0 VIT family Ribosomal_L28e PF01778.17 CEG36191.1 - 5.1e-37 127.1 12.7 5.2e-37 127.1 1.7 3.1 3 0 0 3 3 3 2 Ribosomal L28e protein family Mak16 PF04874.14 CEG36191.1 - 6.9e-31 106.8 17.1 6.9e-31 106.8 17.1 2.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CEG36191.1 - 0.0028 17.1 14.6 0.0039 16.6 14.6 1.1 1 0 0 1 1 1 1 BUD22 GSHPx PF00255.19 CEG36192.1 - 2.3e-29 101.2 0.0 3.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEG36192.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF4497 PF14924.6 CEG36195.1 - 1.8e-13 50.9 0.0 4.4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4497) GATase PF00117.28 CEG36196.1 - 5.3e-16 58.9 0.0 7.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEG36196.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 adh_short_C2 PF13561.6 CEG36197.1 - 2.8e-63 213.6 5.1 3.2e-63 213.4 5.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG36197.1 - 3.1e-46 157.3 3.6 4e-46 157.0 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG36197.1 - 3e-10 40.3 2.8 4.2e-10 39.8 2.2 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEG36197.1 - 0.0091 15.9 3.2 0.021 14.7 2.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CEG36197.1 - 0.045 13.8 0.9 0.086 12.9 0.9 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF484 PF04340.12 CEG36197.1 - 0.051 13.3 0.3 2 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Aldedh PF00171.22 CEG36198.1 - 6.8e-117 390.8 0.0 8.2e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lipase_GDSL_2 PF13472.6 CEG36198.1 - 0.042 14.3 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GATase PF00117.28 CEG36199.1 - 8e-16 58.4 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEG36199.1 - 4.3e-05 23.4 0.0 0.00014 21.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 ERO1 PF04137.15 CEG36200.1 - 8.9e-119 396.8 0.1 1.1e-118 396.4 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CcmH PF03918.14 CEG36200.1 - 8.2 5.7 6.5 1.5 8.1 0.1 2.5 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Myb_DNA-binding PF00249.31 CEG36202.1 - 1.4e-12 47.6 0.5 2.3e-12 46.9 0.5 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PPP4R2 PF09184.11 CEG36203.1 - 0.0031 17.1 32.8 0.0046 16.6 22.7 2.2 2 0 0 2 2 2 2 PPP4R2 Spore_coat_CotO PF14153.6 CEG36203.1 - 0.12 12.3 28.0 0.019 14.9 15.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO BSMAP PF12280.8 CEG36203.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.1 2 1 0 2 2 2 0 Brain specific membrane anchored protein MDM1 PF15501.6 CEG36203.1 - 2.3 7.3 37.3 0.1 11.8 26.9 2.1 2 0 0 2 2 2 0 Nuclear protein MDM1 GAGA_bind PF06217.12 CEG36203.1 - 5 7.3 18.0 0.9 9.8 11.9 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Nop14 PF04147.12 CEG36203.1 - 7.6 4.6 45.9 0.19 9.9 31.3 2.1 2 0 0 2 2 2 0 Nop14-like family Mod_r PF07200.13 CEG36205.1 - 0.49 10.5 8.2 0.38 10.9 1.5 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Aminotran_1_2 PF00155.21 CEG36209.1 - 4.8e-39 134.6 0.0 8.7e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEG36209.1 - 0.0074 15.6 0.1 0.073 12.3 0.0 2.3 2 0 0 2 2 2 1 Beta-eliminating lyase BBS2_C PF14782.6 CEG36210.1 - 3.3e-150 500.7 0.2 3.4e-149 497.3 0.1 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CEG36210.1 - 6.9e-43 145.1 0.2 3.5e-39 133.2 0.1 3.0 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 CEG36210.1 - 2.6e-39 133.3 0.0 1.3e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 CEG36210.1 - 8.9e-07 28.3 0.8 0.44 9.5 0.0 4.0 1 1 4 5 5 5 3 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CEG36210.1 - 0.0021 18.6 0.4 3.8 8.2 0.0 3.4 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Rad60-SLD PF11976.8 CEG36210.1 - 0.043 13.7 0.2 0.79 9.6 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like PHTB1_N PF14727.6 CEG36210.1 - 0.052 12.9 0.0 11 5.2 0.0 2.8 3 0 0 3 3 3 0 PTHB1 N-terminus Ham1p_like PF01725.16 CEG36211.1 - 2.3e-52 177.6 0.0 2.6e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF5621 PF18532.1 CEG36211.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) Rhodanese PF00581.20 CEG36212.1 - 8.5e-11 42.3 0.0 1.1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain PTPlike_phytase PF14566.6 CEG36212.1 - 0.048 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate BRCT PF00533.26 CEG36213.1 - 1.3e-20 73.5 0.0 1.7e-05 25.1 0.0 5.6 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEG36213.1 - 1.3e-16 60.3 3.9 1.3e-10 41.0 0.0 5.4 5 0 0 5 5 5 2 twin BRCT domain BRCT_2 PF16589.5 CEG36213.1 - 1.6e-15 57.2 0.0 0.014 15.8 0.1 6.6 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CEG36213.1 - 1.3e-09 37.8 0.0 1.3e-07 31.4 0.0 3.1 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain COG4 PF08318.12 CEG36214.1 - 2.9e-30 105.5 0.0 4.8e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein Sec15 PF04091.12 CEG36214.1 - 0.0017 17.8 5.7 0.0021 17.5 0.7 3.2 3 2 0 3 3 3 1 Exocyst complex subunit Sec15-like DIL PF01843.19 CEG36214.1 - 0.0052 17.0 3.3 0.0093 16.2 0.0 3.0 3 0 0 3 3 3 1 DIL domain Vps53_N PF04100.12 CEG36214.1 - 0.0088 15.1 0.9 0.03 13.3 0.6 2.1 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec6 PF06046.13 CEG36214.1 - 0.029 12.8 0.4 4.1 5.7 0.1 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec6 RsbRD_N PF14361.6 CEG36214.1 - 1.9 9.2 6.3 3.1 8.5 0.2 4.0 5 1 1 6 6 6 0 RsbT co-antagonist protein rsbRD N-terminal domain SPRY PF00622.28 CEG36215.1 - 7.4e-29 100.3 0.0 2.5e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 SPRY domain UBA PF00627.31 CEG36215.1 - 0.00072 19.4 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HECT PF00632.25 CEG36221.1 - 1.2e-46 159.6 0.0 1.5e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank PF00023.30 CEG36223.1 - 7e-29 99.0 1.6 2.9e-05 24.3 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 CEG36223.1 - 3.8e-27 94.7 4.5 1.8e-12 47.7 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG36223.1 - 2.4e-25 85.8 4.0 0.0035 17.7 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 CEG36223.1 - 1.4e-22 79.7 2.1 5.1e-11 42.9 0.0 4.9 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG36223.1 - 6.5e-20 70.9 2.4 2.9e-07 30.6 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Orf78 PF06024.12 CEG36223.1 - 0.12 12.7 0.3 0.3 11.4 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DNA_pol_A_exo1 PF01612.20 CEG36225.1 - 0.042 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease XPG_I PF00867.18 CEG36225.1 - 0.16 12.4 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 XPG I-region Pkinase PF00069.25 CEG36226.1 - 4.1e-121 403.3 0.6 1.3e-39 136.2 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36226.1 - 2.4e-68 230.2 0.0 1e-34 120.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG36226.1 - 4.5e-10 38.9 0.2 6.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CEG36226.1 - 1.5e-07 31.6 0.2 0.0082 16.1 0.0 3.4 3 1 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG36226.1 - 5e-05 22.7 0.0 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 CEG36226.1 - 0.0022 17.1 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 Haspin_kinase PF12330.8 CEG36226.1 - 0.058 12.3 0.1 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Haspin like kinase domain CTP_transf_1 PF01148.20 CEG36227.1 - 0.0012 18.7 5.0 0.0024 17.7 5.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase family PLDc_2 PF13091.6 CEG36228.1 - 5e-18 65.3 0.0 5.1e-09 36.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEG36228.1 - 0.022 14.9 2.2 1.3 9.3 0.1 3.2 3 0 0 3 3 3 0 Phospholipase D Active site motif Adaptin_binding PF10199.9 CEG36229.1 - 9.6e-15 55.3 6.6 1.7e-14 54.4 6.6 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF2325 PF10087.9 CEG36229.1 - 0.056 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) NPR1_interact PF15699.5 CEG36229.1 - 0.19 12.4 3.6 0.19 12.4 0.4 2.2 2 0 0 2 2 2 0 NPR1 interacting Prefoldin PF02996.17 CEG36230.1 - 1.9e-26 92.3 0.7 1.9e-26 92.3 0.7 2.2 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 CEG36230.1 - 0.0014 18.6 0.0 0.0061 16.6 0.0 2.2 1 0 0 1 1 1 1 Prefoldin subunit Ssl1 PF04056.14 CEG36230.1 - 0.05 13.4 1.9 0.11 12.3 0.5 2.0 2 0 0 2 2 2 0 Ssl1-like DASH_Dad2 PF08654.10 CEG36230.1 - 0.57 10.6 5.9 15 6.1 0.1 3.2 2 1 0 2 2 2 0 DASH complex subunit Dad2 Aida_N PF08910.10 CEG36230.1 - 5.8 7.4 6.7 0.56 10.6 0.5 2.5 3 0 0 3 3 3 0 Aida N-terminus DUF4750 PF15938.5 CEG36231.1 - 4.4e-18 64.7 1.5 5.1e-18 64.5 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) DUF1656 PF07869.12 CEG36231.1 - 0.0054 16.7 1.1 0.0073 16.3 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) WD40 PF00400.32 CEG36232.1 - 2e-26 91.7 17.9 4.6e-05 24.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat WW PF00397.26 CEG36232.1 - 1.9e-07 31.0 0.3 5.3e-07 29.6 0.3 1.8 1 0 0 1 1 1 1 WW domain ANAPC4_WD40 PF12894.7 CEG36232.1 - 3.4e-07 30.5 4.5 0.0032 17.7 1.9 3.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG36232.1 - 0.021 13.5 6.4 0.036 12.7 0.8 3.1 1 1 0 3 3 3 0 Nucleoporin Nup120/160 RsfS PF02410.15 CEG36233.1 - 2.6e-22 79.1 0.4 1.2e-21 77.0 0.2 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation FAM221 PF14753.6 CEG36234.1 - 0.049 13.2 1.0 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein FAM221A/B Caprin-1_dimer PF18293.1 CEG36234.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.9 2 2 1 3 3 3 0 Caprin-1 dimerization domain DUF5595 PF18077.1 CEG36234.1 - 0.24 11.5 0.2 0.24 11.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Lebercilin PF15619.6 CEG36234.1 - 3 7.5 38.3 3 7.5 18.2 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMCO5 PF14992.6 CEG36234.1 - 7.6 6.0 31.0 13 5.2 11.7 3.2 1 1 1 2 2 2 0 TMCO5 family Syndecan PF01034.20 CEG36237.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Glyco_hydro_72 PF03198.14 CEG36238.1 - 5.8e-22 78.3 2.9 9.4e-17 61.2 1.5 3.1 2 1 0 2 2 2 2 Glucanosyltransferase RVT_2 PF07727.14 CEG36238.1 - 2e-05 24.4 0.0 4.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LapA_dom PF06305.11 CEG36238.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EGF_alliinase PF04863.13 CEG36238.1 - 0.15 12.5 11.3 0.51 10.8 11.3 2.0 1 0 0 1 1 1 0 Alliinase EGF-like domain YchF-GTPase_C PF06071.13 CEG36239.1 - 1.7e-29 101.8 0.3 4.2e-29 100.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CEG36239.1 - 9.4e-19 67.6 0.0 2.7e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG36239.1 - 3.1e-06 26.8 0.1 9.1e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CEG36239.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CEG36239.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 CEG36240.1 - 1.3e-135 451.6 0.0 1.8e-132 441.3 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CEG36240.1 - 6.2e-91 304.3 0.0 1.2e-90 303.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 CEG36240.1 - 1.6e-89 300.8 2.5 4.6e-89 299.3 2.5 1.9 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG36240.1 - 2.8e-76 256.7 0.0 7.2e-76 255.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG36240.1 - 2e-75 252.7 0.7 2.3e-74 249.2 0.3 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CEG36240.1 - 3.3e-70 236.8 11.6 5.1e-70 236.2 11.6 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 CEG36240.1 - 3.6e-59 199.3 0.9 1.1e-54 184.7 0.1 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG36240.1 - 2.4e-50 170.5 0.2 1.6e-48 164.7 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Kelch_5 PF13854.6 CEG36240.1 - 4e-35 119.2 0.6 6.8e-07 29.1 0.2 6.9 6 0 0 6 6 6 6 Kelch motif Dynein_heavy PF03028.15 CEG36240.1 - 1.6e-32 112.1 0.0 6.1e-32 110.2 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Kelch_4 PF13418.6 CEG36240.1 - 3.3e-29 100.6 12.4 4.4e-07 29.8 0.0 7.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG36240.1 - 6.7e-26 89.7 11.5 1.1e-05 25.5 0.0 6.8 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CEG36240.1 - 8.3e-24 83.3 5.8 7.5e-09 35.7 0.0 6.5 6 0 0 6 6 5 4 Galactose oxidase, central domain AAA_lid_1 PF17857.1 CEG36240.1 - 1.1e-22 80.1 1.9 4.8e-22 78.0 0.4 3.0 3 0 0 3 3 1 1 AAA+ lid domain Kelch_1 PF01344.25 CEG36240.1 - 1.1e-22 79.3 8.5 0.00013 21.5 0.1 6.3 6 0 0 6 6 6 4 Kelch motif AAA_5 PF07728.14 CEG36240.1 - 6.2e-22 78.1 0.0 6.4e-09 35.9 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEG36240.1 - 1.3e-19 70.5 2.7 3.4e-19 69.2 2.7 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 CEG36240.1 - 1.9e-14 54.3 0.0 6.3e-14 52.7 0.0 2.0 2 0 0 2 2 1 1 Filamin/ABP280 repeat Kelch_2 PF07646.15 CEG36240.1 - 3.6e-14 52.1 12.5 1.7e-05 24.6 0.2 6.6 7 0 0 7 7 5 4 Kelch motif AAA_16 PF13191.6 CEG36240.1 - 2.4e-07 31.3 0.1 1.9 8.9 0.0 5.3 5 0 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 CEG36240.1 - 7.6e-07 29.7 0.1 3.5 8.2 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 CEG36240.1 - 3.1e-06 27.5 0.8 1.4 9.2 0.0 4.7 5 0 0 5 5 3 1 AAA domain AAA_33 PF13671.6 CEG36240.1 - 5e-05 23.5 0.5 0.5 10.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 CEG36240.1 - 8e-05 23.1 0.6 3.2 8.2 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CEG36240.1 - 0.00037 20.9 3.5 0.072 13.4 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CEG36240.1 - 0.0018 18.0 0.3 16 5.1 0.1 4.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CEG36240.1 - 0.0087 16.4 0.6 21 5.6 0.0 4.1 4 0 0 4 4 3 0 RNA helicase TIG PF01833.24 CEG36240.1 - 0.0091 16.0 0.4 0.025 14.6 0.4 1.8 1 0 0 1 1 1 1 IPT/TIG domain Sigma54_activat PF00158.26 CEG36240.1 - 0.025 14.3 0.1 1.6 8.4 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Invasin_D3 PF09134.10 CEG36240.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Invasin, domain 3 AAA_28 PF13521.6 CEG36240.1 - 0.19 12.0 0.7 53 4.0 0.1 3.7 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 CEG36240.1 - 0.22 11.2 5.6 1.4 8.7 0.0 4.2 4 0 0 4 4 4 0 AAA domain DUF1168 PF06658.12 CEG36241.1 - 9.6e-25 87.0 18.4 9.6e-25 87.0 18.4 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) MDM10 PF12519.8 CEG36241.1 - 0.13 11.1 5.8 0.14 11.0 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Selenoprotein_S PF06936.11 CEG36241.1 - 0.2 11.4 11.5 0.4 10.5 11.5 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) ArAE_2_N PF10337.9 CEG36241.1 - 1.9 7.4 3.3 2.4 7.1 3.3 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Presenilin PF01080.17 CEG36241.1 - 3.5 6.3 4.0 3.6 6.3 4.0 1.1 1 0 0 1 1 1 0 Presenilin Myb_DNA-bind_7 PF15963.5 CEG36243.1 - 0.0017 18.2 0.2 0.94 9.4 0.0 2.9 2 0 0 2 2 2 2 Myb DNA-binding like DUF659 PF04937.15 CEG36243.1 - 0.003 17.4 0.0 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CEG36243.1 - 0.013 15.3 0.1 0.057 13.2 0.1 2.1 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-BED PF02892.15 CEG36243.1 - 0.049 13.7 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 BED zinc finger FTHFS PF01268.19 CEG36243.1 - 0.18 10.0 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF5600 PF18150.1 CEG36243.1 - 0.51 10.9 2.6 0.61 10.7 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) HTH_19 PF12844.7 CEG36245.1 - 4.1e-06 26.7 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CEG36245.1 - 1.2e-05 25.6 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 CEG36245.1 - 1.8e-05 24.7 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 Helix-turn-helix Pou PF00157.17 CEG36245.1 - 0.035 14.1 0.1 0.68 10.0 0.1 2.2 1 1 1 2 2 2 0 Pou domain - N-terminal to homeobox domain DndB PF14072.6 CEG36246.1 - 5.7e-107 357.9 0.6 2.1e-106 356.0 0.0 2.2 2 0 0 2 2 2 1 DNA-sulfur modification-associated SMC_N PF02463.19 CEG36246.1 - 8.7e-11 41.7 0.9 7.3e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG36246.1 - 8.7e-10 39.4 53.0 0.00019 22.0 45.8 4.7 2 1 0 2 2 2 1 AAA domain PAPS_reduct PF01507.19 CEG36246.1 - 4.9e-08 33.2 0.0 2.6e-07 30.9 0.0 2.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PSK_trans_fac PF07704.11 CEG36246.1 - 0.36 11.6 8.6 5.4 7.8 0.0 4.9 4 0 0 4 4 4 0 Rv0623-like transcription factor AAA_21 PF13304.6 CEG36246.1 - 1.2 8.9 7.8 0.14 12.0 0.2 3.2 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 CEG36247.1 - 5.5e-09 36.5 0.1 7.4e-08 32.8 0.0 3.1 2 1 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CEG36247.1 - 2.8e-05 23.2 0.7 0.023 13.6 0.2 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 CEG36247.1 - 0.00016 22.0 0.3 2.2 8.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CEG36247.1 - 0.0062 15.9 0.1 0.12 11.7 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family ABC_tran PF00005.27 CEG36247.1 - 0.01 16.4 0.2 7.4 7.1 0.0 3.4 3 0 0 3 3 2 1 ABC transporter AAA_16 PF13191.6 CEG36247.1 - 0.012 16.0 0.0 0.29 11.5 0.0 3.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CEG36247.1 - 0.028 14.6 0.1 38 4.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEG36247.1 - 0.045 14.3 0.1 0.95 10.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain Inv-AAD PF18785.1 CEG36247.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase RsgA_GTPase PF03193.16 CEG36247.1 - 0.11 12.3 0.6 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 CEG36247.1 - 0.16 12.4 0.0 17 5.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase TetR_C_8 PF14278.6 CEG36247.1 - 0.89 9.7 4.9 0.39 10.8 0.2 2.9 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region DUF2115 PF09888.9 CEG36247.1 - 5.2 7.6 8.7 0.61 10.6 0.1 3.6 4 0 0 4 4 3 0 Uncharacterized protein conserved in archaea (DUF2115) AAA_16 PF13191.6 CEG36248.1 - 0.15 12.4 0.0 0.62 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain UPF0147 PF03685.13 CEG36250.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Amelogenin PF02948.15 CEG36251.1 - 0.034 14.8 0.0 3.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Amelogenin Vps26 PF03643.15 CEG36252.1 - 3.4e-80 269.0 2.4 4e-80 268.7 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CEG36252.1 - 0.0064 17.0 0.1 1.1 9.7 0.0 2.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.22 CEG36253.1 - 1.4e-28 98.5 0.0 2.5e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEG36253.1 - 0.00042 20.3 1.2 0.082 13.0 0.1 2.7 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 CEG36253.1 - 0.0037 17.3 0.0 0.013 15.6 0.0 1.8 2 1 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 CEG36253.1 - 0.0074 16.4 0.0 0.029 14.5 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CEG36253.1 - 0.038 13.6 0.0 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CEG36253.1 - 0.047 13.7 0.2 11 6.0 0.0 2.9 2 1 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 CEG36253.1 - 0.081 12.8 0.0 13 5.7 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CEG36253.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hid1 PF12722.7 CEG36254.1 - 0.28 9.3 7.4 0.27 9.3 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 CEG36254.1 - 0.64 10.1 5.5 0.83 9.8 5.5 1.4 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.6 CEG36254.1 - 5 7.7 10.7 6.6 7.3 10.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 CEG36254.1 - 5.8 6.6 13.1 8 6.2 13.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPRTase PF14681.6 CEG36255.1 - 8e-25 87.5 0.5 1.2e-24 86.9 0.5 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HTH_23 PF13384.6 CEG36255.1 - 0.047 13.5 0.1 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 CEG36255.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LRR_8 PF13855.6 CEG36258.1 - 2e-07 30.6 8.8 0.0027 17.4 0.5 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CEG36258.1 - 0.00039 20.7 6.3 0.033 14.6 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) ASF1_hist_chap PF04729.13 CEG36261.1 - 0.014 15.4 0.0 0.095 12.6 0.0 2.0 1 1 0 1 1 1 0 ASF1 like histone chaperone FeS_assembly_P PF01883.19 CEG36262.1 - 1.6e-13 50.6 0.0 3.5e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein PIGA PF08288.12 CEG36262.1 - 0.0043 17.6 0.0 0.0088 16.6 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) PP2C PF00481.21 CEG36263.1 - 2.5e-20 73.2 0.0 2.8e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Proteasome PF00227.26 CEG36265.1 - 2.9e-56 190.0 0.0 4.2e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEG36265.1 - 7.6e-14 51.1 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TACC_C PF05010.14 CEG36265.1 - 0.078 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IF2_assoc PF08364.11 CEG36267.1 - 0.043 14.1 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region PLAC8 PF04749.17 CEG36269.1 - 1.2e-06 29.5 0.5 4.2e-06 27.7 0.5 1.9 1 0 0 1 1 1 1 PLAC8 family Phage_holin_3_6 PF07332.11 CEG36269.1 - 0.0028 17.7 1.0 0.0058 16.7 1.0 1.5 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 CEG36269.1 - 0.0097 15.7 1.0 0.015 15.1 1.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 CEG36269.1 - 0.07 11.9 1.1 0.11 11.2 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3810 PF12725.7 CEG36269.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) LapA_dom PF06305.11 CEG36269.1 - 0.17 11.7 1.4 8.9 6.2 0.2 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PDGF PF00341.17 CEG36269.1 - 1.6 9.1 8.2 5.4 7.4 8.0 2.0 1 1 0 1 1 1 0 PDGF/VEGF domain fn3 PF00041.21 CEG36270.1 - 2.4e-91 300.2 65.2 4.3e-08 33.4 0.3 29.1 30 2 0 30 30 30 19 Fibronectin type III domain PA14 PF07691.12 CEG36270.1 - 4.1e-62 208.4 0.9 4.7e-21 75.1 0.1 5.2 5 0 0 5 5 5 3 PA14 domain Filamin PF00630.19 CEG36270.1 - 2.6e-27 95.6 0.0 2e-07 31.8 0.1 9.1 8 1 0 8 8 8 4 Filamin/ABP280 repeat Pur_ac_phosph_N PF16656.5 CEG36270.1 - 1.7e-09 38.2 33.6 0.046 14.3 0.1 15.3 16 1 0 16 16 16 2 Purple acid Phosphatase, N-terminal domain POTRA_1 PF08478.10 CEG36270.1 - 3.8e-06 27.1 1.9 8.1 6.8 0.0 7.6 10 0 0 10 10 10 2 POTRA domain, FtsQ-type GLEYA PF10528.9 CEG36270.1 - 0.00012 22.5 4.9 2.7 8.5 0.1 6.6 6 0 0 6 6 6 2 GLEYA domain DUF2369 PF10179.9 CEG36270.1 - 0.25 11.8 5.0 50 4.4 0.1 6.5 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) DUF5312 PF17239.2 CEG36272.1 - 0.012 14.0 0.4 0.028 12.8 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5312) DUF4143 PF13635.6 CEG36272.1 - 0.05 13.8 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4143) PCM1_C PF15717.5 CEG36273.1 - 1.7 7.2 26.5 2.1 6.9 26.5 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Catalase PF00199.19 CEG36274.1 - 1.2e-189 630.4 0.1 1.5e-189 630.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEG36274.1 - 1.2e-20 73.5 0.4 7.4e-20 70.9 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive F420_oxidored PF03807.17 CEG36276.1 - 1.2e-08 35.4 0.0 4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CEG36276.1 - 0.0041 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 CEG36276.1 - 0.0088 16.3 0.0 0.21 11.8 0.0 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 CEG36276.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PTA_PTB PF01515.19 CEG36277.1 - 5.5e-118 393.9 1.2 8.2e-118 393.3 1.2 1.3 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 CEG36277.1 - 2.1e-17 63.6 0.0 3.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 CEG36277.1 - 6.3e-16 58.1 0.3 2.9e-15 55.9 0.1 2.3 2 0 0 2 2 2 1 DRTGG domain CbiA PF01656.23 CEG36277.1 - 0.004 17.2 0.1 0.13 12.3 0.0 3.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1018 PF06252.12 CEG36277.1 - 0.081 13.9 0.5 1 10.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) EGF_2 PF07974.13 CEG36278.1 - 5.1e-22 77.9 113.0 4.2e-05 23.8 3.1 11.2 12 0 0 12 12 12 9 EGF-like domain Laminin_EGF PF00053.24 CEG36278.1 - 0.00092 19.3 87.5 0.059 13.5 1.7 8.2 8 1 1 9 9 9 7 Laminin EGF domain EGF PF00008.27 CEG36278.1 - 0.0018 18.5 8.7 0.0018 18.5 8.7 11.8 13 0 0 13 13 13 7 EGF-like domain hEGF PF12661.7 CEG36278.1 - 0.0029 18.2 3.5 0.0029 18.2 3.5 11.7 11 0 0 11 11 11 5 Human growth factor-like EGF Ribonuc_red_lgN PF00317.21 CEG36278.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain AAA PF00004.29 CEG36281.1 - 3e-16 60.0 0.0 5.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CEG36281.1 - 2.6e-12 47.0 0.3 7.9e-12 45.4 0.1 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CEG36281.1 - 3.4e-12 46.5 0.0 1e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CEG36281.1 - 5.3e-06 26.7 0.2 2.3e-05 24.6 0.0 2.1 3 0 0 3 3 2 1 AAA C-terminal domain AAA_16 PF13191.6 CEG36281.1 - 1.6e-05 25.3 0.1 0.00065 20.1 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CEG36281.1 - 2.2e-05 24.4 0.0 4.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CEG36281.1 - 7.7e-05 22.5 0.0 0.00035 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG36281.1 - 0.00013 22.2 0.0 0.17 12.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 CEG36281.1 - 0.00021 21.1 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG36281.1 - 0.00034 20.5 0.1 0.0011 18.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 CEG36281.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CEG36281.1 - 0.011 15.1 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 CEG36281.1 - 0.016 15.3 0.0 0.045 13.8 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEG36281.1 - 0.017 15.4 0.1 0.051 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEG36281.1 - 0.037 13.7 0.0 0.23 11.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 CEG36281.1 - 0.046 13.7 0.3 0.73 9.8 0.1 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF5338 PF17273.2 CEG36281.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) DEAD PF00270.29 CEG36281.1 - 0.055 13.2 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 CEG36281.1 - 0.069 13.7 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG36281.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 CEG36282.1 - 4e-11 43.3 5.8 0.027 15.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36282.1 - 0.00016 21.9 0.1 0.039 14.2 0.0 3.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PTCB-BRCT PF12738.7 CEG36283.1 - 2.2e-08 33.9 0.1 4.5e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CEG36283.1 - 4.2e-06 27.1 0.0 8.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEG36283.1 - 0.00093 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CEG36283.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Ras PF00071.22 CEG36284.1 - 9.3e-67 223.7 1.0 1.1e-66 223.4 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG36284.1 - 6.7e-37 126.4 0.7 1.9e-36 124.9 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG36284.1 - 4.6e-18 65.3 0.1 5.6e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEG36284.1 - 4.5e-06 26.7 0.9 0.06 13.2 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEG36284.1 - 6.3e-06 25.7 0.1 8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEG36284.1 - 2e-05 24.1 0.1 2.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG36284.1 - 2.5e-05 24.3 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG36284.1 - 6.8e-05 22.5 0.4 0.00015 21.3 0.2 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CEG36284.1 - 0.0018 18.7 0.4 0.29 11.6 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CEG36284.1 - 0.0036 16.9 0.1 0.025 14.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 CEG36284.1 - 0.0056 16.2 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 CEG36284.1 - 0.021 14.6 0.1 0.44 10.3 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 CEG36284.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG36284.1 - 0.031 14.6 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CEG36284.1 - 0.041 14.2 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEG36284.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 CEG36284.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 CEG36284.1 - 0.06 13.9 0.0 0.089 13.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CEG36284.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Atg8 PF02991.16 CEG36286.1 - 5.6e-51 171.1 0.1 7e-51 170.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CEG36286.1 - 9.8e-07 29.1 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 WD40 PF00400.32 CEG36287.1 - 1.3e-13 51.2 35.2 2e-05 25.3 0.2 10.3 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36287.1 - 7.2e-08 32.6 2.4 0.78 10.1 0.1 5.9 6 1 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEG36287.1 - 0.0026 18.2 1.2 0.46 11.0 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain Vps16_N PF04841.13 CEG36287.1 - 0.0047 15.7 0.0 0.0087 14.9 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region RVT_1 PF00078.27 CEG36288.1 - 6.3e-08 32.4 0.0 6.8e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXLR_WY PF18634.1 CEG36290.1 - 0.0013 18.6 0.0 0.037 13.9 0.1 2.9 2 0 0 2 2 2 1 RXLR phytopathogen effector protein WY-domain RXLR PF16810.5 CEG36290.1 - 0.036 14.5 0.3 0.25 11.8 0.0 2.6 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity DASH_Hsk3 PF08227.11 CEG36290.1 - 0.051 13.9 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like UDPG_MGDP_dh_N PF03721.14 CEG36294.1 - 1e-54 185.0 0.3 1.7e-54 184.3 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CEG36294.1 - 5.1e-35 120.1 0.1 4e-33 114.0 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CEG36294.1 - 2.2e-31 107.9 0.0 4.9e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 CEG36294.1 - 0.016 15.4 0.2 0.25 11.5 0.0 2.8 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase PriCT_2 PF08707.11 CEG36297.1 - 0.0073 16.7 0.5 0.0091 16.4 0.5 1.2 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) Sad1_UNC PF07738.13 CEG36299.1 - 1.3e-31 109.4 0.0 3e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 CEG36299.1 - 0.0045 17.1 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF4457 PF14652.6 CEG36299.1 - 0.0093 15.2 0.0 0.16 11.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4457) DUF5000 PF16391.5 CEG36299.1 - 0.14 12.3 0.1 0.31 11.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function BHD_3 PF10405.9 CEG36300.1 - 1.3e-24 86.3 0.0 2.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CEG36300.1 - 7.1e-17 61.5 3.6 1.6e-16 60.3 3.6 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 CEG36300.1 - 1.7e-14 53.4 0.0 3.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CEG36300.1 - 4.9e-10 40.2 2.9 4.9e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Aminotran_4 PF01063.19 CEG36300.1 - 0.019 14.9 0.9 6.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Amino-transferase class IV DUF2570 PF10828.8 CEG36300.1 - 0.037 13.9 1.6 11 5.9 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) UCH PF00443.29 CEG36301.1 - 4e-60 203.5 0.0 8e-60 202.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEG36301.1 - 9.1e-21 74.3 0.0 2e-19 70.0 0.0 3.2 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 CEG36301.1 - 2.7e-09 37.0 0.7 0.0014 18.3 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 CEG36301.1 - 6.8e-05 22.1 0.1 0.00018 20.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG36301.1 - 0.00085 19.1 0.0 0.004 17.0 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CEG36301.1 - 0.0017 18.2 0.0 0.0055 16.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CEG36301.1 - 0.021 15.3 0.0 0.077 13.5 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 CEG36301.1 - 0.059 12.9 0.7 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 EF hand PHB_acc_N PF07879.11 CEG36302.1 - 0.17 12.0 0.3 58 3.9 0.0 3.3 4 0 0 4 4 4 0 PHB/PHA accumulation regulator DNA-binding domain Elf1 PF05129.13 CEG36304.1 - 2.5e-30 104.3 4.7 2.8e-30 104.2 4.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 CEG36304.1 - 0.033 14.2 3.7 0.85 9.7 0.4 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_4 PF13894.6 CEG36304.1 - 0.5 11.3 5.4 7.8 7.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.12 CEG36304.1 - 0.63 10.3 6.6 0.19 12.0 1.4 2.1 1 1 2 3 3 3 0 TFIIH C1-like domain DDE_3 PF13358.6 CEG36307.1 - 0.064 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF3110 PF11360.8 CEG36307.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) CREPT PF16566.5 CEG36308.1 - 0.0053 16.9 4.1 0.0053 16.9 4.1 4.7 1 1 3 4 4 4 1 Cell-cycle alteration and expression-elevated protein in tumour DUF3584 PF12128.8 CEG36308.1 - 0.06 10.9 48.1 0.0053 14.4 34.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 CEG36308.1 - 0.28 10.0 48.1 0.67 8.8 47.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Adhesin_P1_N PF18652.1 CEG36308.1 - 6.8 6.8 9.9 5.1 7.2 0.1 3.3 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain ATG16 PF08614.11 CEG36308.1 - 8.5 6.6 52.6 0.15 12.3 8.7 4.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) La PF05383.17 CEG36309.1 - 5.4e-18 64.8 0.1 1.5e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 CEG36309.1 - 1.5e-15 57.1 2.8 5.4e-10 39.2 0.2 4.5 4 0 0 4 4 4 2 RNA binding motif SRP19 PF01922.17 CEG36309.1 - 0.068 14.1 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 SRP19 protein DUF4144 PF13642.6 CEG36309.1 - 0.15 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 protein structure with unknown function Mito_carr PF00153.27 CEG36310.1 - 2e-63 210.3 3.8 9.3e-23 80.0 0.4 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEG36310.1 - 0.033 13.3 0.2 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease ASH PF15780.5 CEG36311.1 - 1.2e-07 31.8 0.1 0.0059 16.8 0.0 3.3 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CEG36311.1 - 0.00058 19.7 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain F5_F8_type_C PF00754.25 CEG36312.1 - 9.5e-05 22.5 0.2 0.00024 21.2 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain VEFS-Box PF09733.9 CEG36313.1 - 7.9e-42 142.3 3.1 1.5e-41 141.5 3.1 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Hemocyanin_N PF03722.14 CEG36313.1 - 0.36 11.3 2.9 0.59 10.7 1.2 2.3 2 1 0 2 2 2 0 Hemocyanin, all-alpha domain PPI_Ypi1 PF07491.11 CEG36314.1 - 3.1e-18 65.3 5.2 3.1e-18 65.3 5.2 2.1 1 1 1 2 2 2 1 Protein phosphatase inhibitor YL1 PF05764.13 CEG36314.1 - 0.0031 17.7 3.0 0.0033 17.6 3.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein TFIIF_alpha PF05793.12 CEG36314.1 - 0.15 10.7 11.7 0.18 10.4 11.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GEN1_C PF18380.1 CEG36314.1 - 0.18 12.7 5.8 0.67 10.9 5.8 2.0 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CDC45 PF02724.14 CEG36314.1 - 0.24 9.6 5.7 0.28 9.4 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3433 PF11915.8 CEG36315.1 - 0.014 15.9 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Pkinase PF00069.25 CEG36316.1 - 1.5e-19 70.4 0.3 2.5e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain WW PF00397.26 CEG36316.1 - 1.1e-14 54.2 0.6 6.6e-07 29.3 0.2 2.6 2 0 0 2 2 2 2 WW domain LBR_tudor PF09465.10 CEG36318.1 - 0.00044 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain rve PF00665.26 CEG36319.1 - 1.3e-21 77.0 0.0 2.7e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG36319.1 - 5.6e-09 35.7 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CEG36319.1 - 3.5e-05 23.5 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MIase PF02426.16 CEG36323.1 - 0.008 16.3 0.2 0.036 14.2 0.2 2.1 1 0 0 1 1 1 1 Muconolactone delta-isomerase IQ PF00612.27 CEG36323.1 - 0.018 14.8 3.1 0.1 12.5 3.1 2.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif QslA_E PF18226.1 CEG36323.1 - 0.63 10.0 3.4 0.78 9.7 0.1 2.9 3 0 0 3 3 3 0 LasR-specific antiactivator QslA chain E MtrG PF04210.13 CEG36323.1 - 1.8 8.5 3.1 0.99 9.3 0.2 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pkinase PF00069.25 CEG36325.1 - 4.7e-50 170.4 0.0 6.8e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36325.1 - 8.5e-48 162.9 0.0 1.3e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG36325.1 - 1.9e-12 46.8 5.8 9.3e-07 28.5 0.8 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEG36325.1 - 3.4e-08 33.7 8.3 0.00027 21.3 0.4 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG36325.1 - 4.5e-06 26.5 4.9 1.7 9.5 0.0 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat Haspin_kinase PF12330.8 CEG36325.1 - 0.0028 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain LRR_6 PF13516.6 CEG36325.1 - 0.0029 17.5 4.6 0.67 10.2 0.7 4.4 4 0 0 4 4 4 1 Leucine Rich repeat PHtD_u1 PF16645.5 CEG36325.1 - 5.8 7.4 9.2 22 5.6 1.4 3.1 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein CCM2_C PF16545.5 CEG36326.1 - 0.022 15.3 0.0 5.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Syntaxin-6_N PF09177.11 CEG36328.1 - 9.3e-19 67.8 0.4 9.3e-19 67.8 0.4 2.7 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 CEG36328.1 - 4.9e-08 32.8 0.4 1.4e-07 31.4 0.4 1.8 1 0 0 1 1 1 1 SNARE domain Spc7 PF08317.11 CEG36328.1 - 0.0023 16.9 20.1 0.056 12.3 6.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein RNase_T PF00929.24 CEG36328.1 - 0.012 16.1 2.4 0.015 15.9 1.4 1.5 1 1 1 2 2 2 0 Exonuclease DUF1664 PF07889.12 CEG36328.1 - 0.066 13.3 13.8 5.3 7.1 8.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tom37 PF10568.9 CEG36328.1 - 0.11 12.7 1.9 0.13 12.5 0.1 1.9 2 1 0 2 2 2 0 Outer mitochondrial membrane transport complex protein CENP-K PF11802.8 CEG36328.1 - 0.24 11.0 16.6 0.28 10.7 15.9 1.4 1 1 0 1 1 1 0 Centromere-associated protein K zf-C4H2 PF10146.9 CEG36328.1 - 0.3 11.3 13.4 0.13 12.5 9.7 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein FAM76 PF16046.5 CEG36328.1 - 0.43 9.9 11.3 0.49 9.7 11.3 1.2 1 0 0 1 1 1 0 FAM76 protein SLX9 PF15341.6 CEG36328.1 - 0.66 10.4 10.1 0.99 9.8 9.5 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 TBCA PF02970.16 CEG36328.1 - 1.1 9.6 11.6 0.32 11.3 5.5 2.6 1 1 0 2 2 2 0 Tubulin binding cofactor A DUF5082 PF16888.5 CEG36328.1 - 1.1 9.5 12.4 1.6 9.0 11.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CortBP2 PF09727.9 CEG36328.1 - 3 7.7 20.1 2.9 7.8 14.8 2.0 1 1 1 2 2 2 0 Cortactin-binding protein-2 XhlA PF10779.9 CEG36328.1 - 3.1 8.1 9.1 44 4.4 0.8 3.6 3 0 0 3 3 3 0 Haemolysin XhlA CREPT PF16566.5 CEG36328.1 - 4.9 7.3 15.3 5.6 7.1 9.4 2.8 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Cytochrom_C552 PF02335.15 CEG36328.1 - 7 5.4 10.3 0.26 10.2 2.2 2.0 1 1 1 2 2 2 0 Cytochrome c552 TMPIT PF07851.13 CEG36328.1 - 8.8 5.5 13.3 2.9 7.0 9.4 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 CEG36328.1 - 9.1 5.5 16.6 1.2e+02 1.8 16.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec15 PF04091.12 CEG36329.1 - 1.5e-41 142.8 1.5 1.5e-41 142.8 1.5 2.6 4 0 0 4 4 4 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CEG36329.1 - 4.5e-06 26.6 0.6 2.9e-05 24.1 0.2 2.6 1 1 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 CEG36329.1 - 0.00099 19.2 4.3 0.001 19.2 1.2 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CEG36329.1 - 0.011 15.6 1.1 0.011 15.6 1.1 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HMMR_N PF15905.5 CEG36329.1 - 0.024 14.1 1.0 0.079 12.4 1.0 1.9 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal COG5 PF10392.9 CEG36329.1 - 0.064 13.4 3.0 0.54 10.4 0.5 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF5082 PF16888.5 CEG36329.1 - 0.44 10.8 3.3 0.43 10.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) zf-TRM13_CCCH PF11722.8 CEG36331.1 - 0.033 13.9 2.3 0.05 13.4 2.3 1.3 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Kazal_2 PF07648.15 CEG36332.1 - 2.3e-13 50.1 21.2 8e-09 35.5 2.2 2.9 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG36332.1 - 7.3e-13 48.3 19.5 2.3e-07 30.7 2.0 3.1 3 1 0 3 3 3 2 Kazal-type serine protease inhibitor domain GAF PF01590.26 CEG36336.1 - 3.7e-06 27.6 0.0 4.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEG36336.1 - 6.6e-06 26.5 0.0 6.9e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CEG36336.1 - 0.068 13.5 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 GAF domain Metallophos PF00149.28 CEG36339.1 - 1.7e-16 61.4 2.2 1.7e-16 61.4 2.2 2.0 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG36339.1 - 4.8e-05 23.6 0.1 0.00034 20.8 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Wbp11 PF09429.10 CEG36340.1 - 8.6e-16 58.1 11.6 2.6e-15 56.6 11.6 1.9 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 CEG36340.1 - 4.8e-12 46.4 0.9 4.8e-12 46.4 0.9 3.5 3 1 0 3 3 3 1 mRNA biogenesis factor C2 PF00168.30 CEG36342.1 - 3.1e-10 40.2 0.0 5.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain YwiC PF14256.6 CEG36342.1 - 1.1 9.6 13.2 0.13 12.6 1.8 2.2 1 1 1 2 2 2 0 YwiC-like protein CENP-F_leu_zip PF10473.9 CEG36343.1 - 0.00031 20.8 12.5 0.00031 20.8 12.5 3.5 3 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TTRAP PF14203.6 CEG36343.1 - 0.029 14.4 0.7 0.22 11.5 0.2 2.6 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Amidinotransf PF02274.17 CEG36343.1 - 0.029 13.5 0.3 0.029 13.5 0.3 2.6 3 0 0 3 3 3 0 Amidinotransferase SlyX PF04102.12 CEG36343.1 - 0.099 13.3 0.5 0.099 13.3 0.5 3.8 2 1 1 3 3 3 0 SlyX Cep57_CLD_2 PF14197.6 CEG36343.1 - 1.4 9.0 10.4 0.37 10.9 2.7 3.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1192 PF06698.11 CEG36343.1 - 10 6.3 8.4 6 7.0 0.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Pkinase_Tyr PF07714.17 CEG36344.1 - 1.7e-54 184.8 0.0 4e-49 167.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG36344.1 - 4.4e-45 154.1 0.0 5.6e-40 137.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CEG36344.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG36344.1 - 0.034 13.1 0.0 0.25 10.2 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Acetyltransf_7 PF13508.7 CEG36345.1 - 8.6e-06 26.1 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEG36345.1 - 3.4e-05 23.8 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG36345.1 - 0.0013 19.0 0.1 0.0031 17.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEG36345.1 - 0.0033 17.4 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CEG36345.1 - 0.0048 17.0 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RecR PF02132.15 CEG36345.1 - 0.56 9.8 5.2 1.1 8.9 5.2 1.5 1 0 0 1 1 1 0 RecR protein RMP PF14996.6 CEG36347.1 - 2e-27 96.3 0.4 5.4e-27 94.9 0.4 1.7 1 0 0 1 1 1 1 Retinal Maintenance Acetyltransf_1 PF00583.25 CEG36347.1 - 4.7e-12 46.2 0.0 9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG36347.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG36347.1 - 1.9e-06 28.2 0.0 3.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG36347.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CEG36347.1 - 0.0016 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Uso1_p115_C PF04871.13 CEG36347.1 - 0.0043 17.4 0.4 0.0074 16.7 0.4 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Acetyltransf_4 PF13420.7 CEG36347.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEG36347.1 - 0.035 14.8 0.0 0.062 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HhH-GPD PF00730.25 CEG36348.1 - 5.4e-17 62.2 0.0 1e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CEG36348.1 - 4e-14 52.5 0.1 9.8e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 CEG36348.1 - 5.4e-08 32.3 0.5 1.7e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 CEG36348.1 - 0.047 13.9 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 Pathogenicity locus HHH_8 PF14716.6 CEG36348.1 - 0.068 13.6 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 CEG36348.1 - 0.076 13.4 2.9 0.17 12.3 2.9 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 CEG36348.1 - 0.09 13.4 0.0 0.32 11.6 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Whib PF02467.16 CEG36348.1 - 1.3 9.7 4.0 1 10.0 0.4 2.6 2 1 1 3 3 3 0 Transcription factor WhiB DBD_Tnp_Hermes PF10683.9 CEG36349.1 - 0.035 13.8 0.1 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Hermes transposase DNA-binding domain AAA_25 PF13481.6 CEG36350.1 - 1.4e-20 73.7 0.0 3.6e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEG36350.1 - 1.3e-13 50.9 0.0 2.3e-12 46.8 0.0 2.2 1 1 0 1 1 1 1 KaiC Lon_C PF05362.13 CEG36350.1 - 5.8e-13 48.8 0.1 9.3e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DnaB_C PF03796.15 CEG36350.1 - 4.1e-11 42.7 0.1 7.8e-06 25.4 0.2 2.4 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain ChlI PF13541.6 CEG36350.1 - 1.1e-10 41.3 0.1 2.1e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Rad51 PF08423.11 CEG36350.1 - 1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Rad51 AAA_22 PF13401.6 CEG36350.1 - 1.4e-06 28.6 0.0 2.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEG36350.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CEG36350.1 - 0.00014 21.7 0.0 0.0024 17.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CEG36350.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEG36350.1 - 0.0015 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 CEG36350.1 - 0.0024 18.3 0.0 0.0053 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CEG36350.1 - 0.0052 16.9 0.0 0.018 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CEG36350.1 - 0.0077 16.2 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 CEG36350.1 - 0.0098 15.9 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEG36350.1 - 0.02 14.3 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 CEG36350.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 CEG36350.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CEG36350.1 - 0.07 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEG36350.1 - 0.07 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ParA PF10609.9 CEG36350.1 - 0.079 12.4 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase NACHT PF05729.12 CEG36350.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 CEG36350.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 CEG36350.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CEG36350.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 CEG36350.1 - 0.17 11.2 0.1 0.42 9.9 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin Methyltransf_16 PF10294.9 CEG36351.1 - 7e-26 91.0 0.0 9.5e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEG36351.1 - 2.6e-05 23.9 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CEG36351.1 - 6.6e-05 22.6 0.0 8.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CEG36351.1 - 0.0028 18.3 0.0 0.0056 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG36351.1 - 0.01 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEG36351.1 - 0.051 13.4 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CEG36351.1 - 0.11 13.2 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CEG36351.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4208 PF13907.6 CEG36352.1 - 0.058 13.8 1.9 0.43 11.1 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) SlyX PF04102.12 CEG36352.1 - 0.13 12.9 13.1 4.9 7.9 0.3 5.6 3 2 1 4 4 4 0 SlyX Apolipoprotein PF01442.18 CEG36352.1 - 0.28 11.1 24.4 3.4 7.5 3.5 3.8 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CEG36352.1 - 1.3 9.0 16.0 0.82 9.7 1.9 4.7 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CEG36352.1 - 3.4 7.7 12.7 38 4.3 0.0 4.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ExsD PF16806.5 CEG36352.1 - 4.4 7.2 12.1 0.38 10.6 1.5 3.2 1 1 1 3 3 3 0 Antiactivator protein ExsD Robl_LC7 PF03259.17 CEG36353.1 - 3.3e-09 36.4 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF3395 PF11875.8 CEG36353.1 - 0.075 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Cation_efflux PF01545.21 CEG36354.1 - 2.1e-10 40.7 3.7 3e-10 40.2 3.7 1.2 1 0 0 1 1 1 1 Cation efflux family RPN13_C PF16550.5 CEG36356.1 - 9.1e-27 93.5 2.3 2.5e-25 88.8 0.3 2.5 2 0 0 2 2 2 2 UCH-binding domain Proteasom_Rpn13 PF04683.13 CEG36356.1 - 1.1e-23 83.5 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UIM PF02809.20 CEG36356.1 - 0.84 9.7 8.6 1.9 8.6 3.9 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif CN_hydrolase PF00795.22 CEG36357.1 - 8.6e-23 81.0 0.0 5.3e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_C48 PF02902.19 CEG36357.1 - 3.8e-17 62.8 0.1 6.3e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TMEM107 PF14995.6 CEG36358.1 - 1.2e-05 25.8 4.3 1.2e-05 25.8 4.3 1.9 1 1 1 2 2 2 1 Transmembrane protein Aa_trans PF01490.18 CEG36359.1 - 1.1e-21 77.0 22.8 2.6e-12 46.2 12.9 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG36359.1 - 3.1e-06 26.5 25.7 0.00028 20.0 2.1 3.5 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family SHR3_chaperone PF08229.11 CEG36359.1 - 1.9 7.4 5.7 4.2 6.3 0.0 3.1 2 1 1 3 3 3 0 ER membrane protein SH3 Pkinase PF00069.25 CEG36360.1 - 2.2e-75 253.4 0.0 2.6e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36360.1 - 1e-33 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG36360.1 - 2.2e-08 33.8 0.0 8.2e-06 25.3 0.0 2.6 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CEG36360.1 - 8.3e-08 31.4 0.0 4.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEG36360.1 - 1.9e-05 24.1 0.1 2.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG36360.1 - 0.0048 16.5 0.1 0.0075 15.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CEG36360.1 - 0.048 13.6 0.1 9 6.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CEG36360.1 - 0.09 12.3 0.4 0.49 9.9 0.0 2.1 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL TPR_14 PF13428.6 CEG36361.1 - 1.6e-05 25.3 0.2 6.7e-05 23.4 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36361.1 - 0.00033 20.3 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 CEG36361.1 - 0.0075 16.2 0.1 0.029 14.4 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG36361.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36361.1 - 0.014 15.5 0.0 0.06 13.5 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36361.1 - 0.055 13.7 0.1 0.34 11.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1054 PF06335.12 CEG36361.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Pex24p PF06398.11 CEG36361.1 - 0.074 12.0 0.1 0.16 10.9 0.1 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Aconitase PF00330.20 CEG36364.1 - 3.3e-148 494.5 0.0 4.2e-148 494.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEG36364.1 - 1.9e-45 154.4 0.0 3.5e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain TFIIA PF03153.13 CEG36366.1 - 0.0014 18.7 28.9 0.0021 18.1 28.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF702 PF05142.12 CEG36366.1 - 0.0064 17.0 6.3 0.013 16.0 6.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Plasmodium_Vir PF05795.11 CEG36366.1 - 0.011 15.2 10.9 0.015 14.7 10.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAP65_ASE1 PF03999.12 CEG36366.1 - 0.028 13.1 14.5 0.036 12.8 14.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Apt1 PF10351.9 CEG36366.1 - 0.033 13.1 7.2 0.036 12.9 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC2_membrane_2 PF12679.7 CEG36366.1 - 0.062 12.6 0.2 0.081 12.2 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Macoilin PF09726.9 CEG36366.1 - 0.13 10.8 12.1 0.16 10.5 12.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4746 PF15928.5 CEG36366.1 - 0.17 11.3 13.6 0.24 10.8 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 CEG36366.1 - 0.21 11.7 7.7 0.33 11.0 7.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 CEG36366.1 - 0.22 11.6 12.1 0.3 11.1 12.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CcmD PF04995.14 CEG36366.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.1 2 1 1 3 3 1 0 Heme exporter protein D (CcmD) eIF3_subunit PF08597.10 CEG36366.1 - 0.43 10.4 16.2 0.66 9.8 16.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MAT1 PF06391.13 CEG36366.1 - 0.64 9.8 19.1 0.8 9.5 17.1 1.9 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DDRGK PF09756.9 CEG36366.1 - 0.68 9.5 21.0 1.1 8.9 21.0 1.2 1 0 0 1 1 1 0 DDRGK domain Tim54 PF11711.8 CEG36366.1 - 0.73 8.6 17.9 1 8.1 17.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hamartin PF04388.12 CEG36366.1 - 0.76 8.4 21.0 0.96 8.0 21.0 1.1 1 0 0 1 1 1 0 Hamartin protein eIF-3_zeta PF05091.12 CEG36366.1 - 0.87 8.5 14.2 1.1 8.1 14.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 CEG36366.1 - 1.2 8.0 11.6 1.7 7.5 11.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S64 PF08192.11 CEG36366.1 - 1.5 7.2 15.9 1.9 6.9 15.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4820 PF16091.5 CEG36366.1 - 2.1 7.7 14.9 0.025 14.0 7.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Strabismus PF06638.11 CEG36366.1 - 2.4 6.7 7.6 3.2 6.3 7.6 1.2 1 0 0 1 1 1 0 Strabismus protein ATP-synt_E PF05680.12 CEG36366.1 - 2.9 8.3 18.0 18 5.7 17.6 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF3987 PF13148.6 CEG36366.1 - 3.1 6.7 11.3 4.8 6.1 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Serinc PF03348.15 CEG36366.1 - 4.1 6.2 6.2 6.5 5.6 6.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) NARP1 PF12569.8 CEG36366.1 - 4.8 6.0 13.8 7 5.4 13.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF5427 PF10310.9 CEG36366.1 - 6 5.7 24.4 8.2 5.3 24.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 CEG36366.1 - 6.7 4.9 16.0 8.9 4.5 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4471 PF14740.6 CEG36366.1 - 7 5.8 11.1 9.8 5.3 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) FAM176 PF14851.6 CEG36366.1 - 7.7 6.2 12.1 15 5.2 12.1 1.5 1 0 0 1 1 1 0 FAM176 family PA26 PF04636.13 CEG36366.1 - 8.6 5.2 10.9 12 4.7 10.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HemX PF04375.14 CEG36366.1 - 9.7 5.4 22.7 14 4.8 22.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATPase_gene1 PF09527.10 CEG36367.1 - 1.7e-06 28.0 21.7 0.69 10.1 5.1 4.9 2 1 2 4 4 4 4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter OMP_b-brl PF13505.6 CEG36367.1 - 1.6e-05 25.1 9.8 5.9e-05 23.3 9.8 2.4 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain GT87 PF09594.10 CEG36367.1 - 0.0094 15.7 12.9 15 5.2 0.1 4.9 5 0 0 5 5 5 4 Glycosyltransferase family 87 MspA PF09203.11 CEG36367.1 - 0.034 14.0 5.8 2.2 8.1 5.8 2.1 1 1 0 1 1 1 0 MspA NfrA_C PF13283.6 CEG36367.1 - 0.041 13.4 13.6 18 4.8 0.4 5.4 1 1 5 6 6 6 0 Bacteriophage N adsorption protein A C-term Peptidase_M16 PF00675.20 CEG36370.1 - 1.3e-25 90.1 0.0 3.5e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEG36370.1 - 9.4e-16 58.4 0.0 4e-15 56.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain ETC_C1_NDUFA5 PF04716.14 CEG36371.1 - 0.17 11.7 0.3 0.28 11.0 0.3 1.3 1 0 0 1 1 1 0 ETC complex I subunit conserved region Rsm22 PF09243.10 CEG36372.1 - 2.3e-55 187.8 0.1 7e-55 186.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CEG36372.1 - 1.8e-07 31.1 0.0 8.4e-07 29.0 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG36372.1 - 2.4e-05 25.0 0.0 5.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 CEG36372.1 - 0.0086 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Lipase_3 PF01764.25 CEG36373.1 - 2.3e-32 111.8 0.0 6.5e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DSPc PF00782.20 CEG36373.1 - 2.4e-18 66.3 0.0 4.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PGAP1 PF07819.13 CEG36373.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CEG36373.1 - 0.013 14.8 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 CEG36373.1 - 0.018 15.1 0.0 0.06 13.5 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.8 CEG36373.1 - 0.019 14.5 1.3 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CEG36373.1 - 0.084 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Y_phosphatase PF00102.27 CEG36373.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase YscJ_FliF_C PF08345.11 CEG36374.1 - 0.46 10.8 5.9 0.08 13.3 1.5 1.9 3 0 0 3 3 3 0 Flagellar M-ring protein C-terminal JHY PF15261.6 CEG36374.1 - 4.1 8.1 13.8 1 10.0 10.3 1.9 2 0 0 2 2 2 0 Jhy protein dsRBD2 PF17842.1 CEG36374.1 - 7 6.8 8.7 1.8 8.8 3.8 2.4 2 1 1 3 3 3 0 Double-stranded RNA binding domain 2 Pkinase PF00069.25 CEG36375.1 - 1.3e-50 172.2 0.0 2.1e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36375.1 - 1.8e-27 96.2 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG36375.1 - 9.8e-07 28.4 0.0 2.5e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG36375.1 - 1.2e-05 24.3 0.1 2.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG36375.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CEG36375.1 - 0.15 11.1 0.1 0.29 10.2 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FYVE PF01363.21 CEG36377.1 - 7.6e-11 42.0 13.4 1.5e-10 41.0 11.9 2.2 2 0 0 2 2 2 1 FYVE zinc finger GAF_2 PF13185.6 CEG36377.1 - 5.3e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain Siva PF05458.12 CEG36377.1 - 0.00011 21.9 7.3 0.0003 20.5 7.3 1.7 1 0 0 1 1 1 1 Cd27 binding protein (Siva) FYVE_2 PF02318.16 CEG36377.1 - 0.0053 17.0 6.2 0.017 15.4 6.2 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 CEG36377.1 - 0.021 15.1 5.9 0.021 15.1 5.9 2.0 2 0 0 2 2 2 0 C1 domain GAF PF01590.26 CEG36377.1 - 0.11 13.1 0.1 0.41 11.3 0.0 1.9 2 0 0 2 2 2 0 GAF domain OrfB_Zn_ribbon PF07282.11 CEG36377.1 - 0.54 10.2 7.1 1.5 8.8 7.1 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain MetOD2 PF18548.1 CEG36377.1 - 1.2 9.3 3.9 1 9.5 2.2 1.7 2 0 0 2 2 2 0 Metanogen output domain 2 zf-B_box PF00643.24 CEG36377.1 - 2.4 8.4 9.0 0.3 11.3 4.3 2.0 2 0 0 2 2 2 0 B-box zinc finger UPF0167 PF03691.14 CEG36377.1 - 3 7.6 9.6 0.13 12.0 3.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) TMPIT PF07851.13 CEG36377.1 - 5.8 6.1 5.2 0.75 9.0 0.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein DEP PF00610.21 CEG36378.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GAF_2 PF13185.6 CEG36378.1 - 1.4e-05 25.5 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 CEG36378.1 - 1.4e-05 25.1 26.1 1.8e-05 24.8 21.3 3.1 3 1 1 4 4 3 1 FYVE zinc finger PH PF00169.29 CEG36378.1 - 0.0002 21.8 0.0 0.00057 20.4 0.0 1.8 2 0 0 2 2 1 1 PH domain PH_4 PF15404.6 CEG36378.1 - 0.05 13.4 2.7 0.073 12.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 CEG36378.1 - 0.056 13.7 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Syntaxin_2 PF14523.6 CEG36378.1 - 0.07 13.5 7.2 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Golgin_A5 PF09787.9 CEG36378.1 - 0.19 11.2 11.8 0.34 10.4 11.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 AATF-Che1 PF13339.6 CEG36378.1 - 0.21 12.2 6.6 20 5.8 0.0 2.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2408 PF10303.9 CEG36378.1 - 0.26 11.9 7.1 0.66 10.5 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) AAA_12 PF13087.6 CEG36378.1 - 0.29 10.7 3.2 0.66 9.6 3.2 1.5 1 0 0 1 1 1 0 AAA domain Leu_zip PF15294.6 CEG36378.1 - 1.3 8.5 12.5 3.2 7.2 12.2 1.7 1 1 1 2 2 2 0 Leucine zipper FYVE_2 PF02318.16 CEG36378.1 - 1.4 9.1 9.9 0.76 10.0 5.6 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4407 PF14362.6 CEG36378.1 - 3.7 6.8 9.5 6.4 6.0 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CK2S PF15011.6 CEG36378.1 - 3.8 7.4 10.8 1.6 8.6 6.3 2.5 3 1 1 4 4 3 0 Casein Kinase 2 substrate MetOD2 PF18548.1 CEG36378.1 - 4 7.6 6.9 3.7 7.7 1.9 2.5 1 1 1 2 2 2 0 Metanogen output domain 2 DUF3450 PF11932.8 CEG36378.1 - 9.4 5.5 13.8 16 4.7 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2804 PF10974.8 CEG36379.1 - 0.0086 15.6 0.1 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2804) 2OG-FeII_Oxy_3 PF13640.6 CEG36380.1 - 8.9e-08 32.9 0.0 0.0075 17.1 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Cortex-I_coil PF09304.10 CEG36384.1 - 0.067 13.4 0.0 0.27 11.5 0.0 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil Peptidase_C65 PF10275.9 CEG36385.1 - 0.012 15.1 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase C65 Otubain Adeno_PV PF03910.13 CEG36388.1 - 0.07 11.8 0.5 0.087 11.5 0.5 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV CD52 PF15116.6 CEG36389.1 - 0.034 14.2 0.1 0.063 13.3 0.0 1.5 2 0 0 2 2 2 0 CAMPATH-1 antigen RNase_HII PF01351.18 CEG36392.1 - 2.1e-48 164.8 0.0 3.7e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease HII PX PF00787.24 CEG36392.1 - 5.2e-19 68.3 1.4 1e-18 67.3 0.3 2.1 2 0 0 2 2 2 1 PX domain Peptidase_C92 PF05708.12 CEG36392.1 - 2e-07 31.2 0.1 5.5e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Phage_ASH PF10554.9 CEG36392.1 - 0.025 14.9 0.3 0.082 13.3 0.1 2.0 2 0 0 2 2 2 0 Ash protein family FCH PF00611.23 CEG36394.1 - 3.4e-05 24.0 1.2 6.4e-05 23.2 0.2 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DegT_DnrJ_EryC1 PF01041.17 CEG36394.1 - 0.081 12.2 4.0 0.082 12.2 2.9 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PUB PF09409.10 CEG36395.1 - 1.5e-12 47.2 0.0 4.5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 PUB domain Tctex-1 PF03645.13 CEG36395.1 - 1.3e-11 44.6 0.1 2.8e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Tctex-1 family VSG_B PF13206.6 CEG36395.1 - 0.029 13.6 10.7 0.049 12.9 10.7 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain ALMT PF11744.8 CEG36395.1 - 0.14 10.9 6.4 0.21 10.4 6.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Borrelia_P83 PF05262.11 CEG36395.1 - 0.82 8.1 20.0 1.1 7.6 20.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 CEG36395.1 - 4.4 6.6 29.3 6.6 6.0 29.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) V_ATPase_I PF01496.19 CEG36395.1 - 5.3 4.8 11.0 6.9 4.5 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_5 PF14634.6 CEG36396.1 - 0.00068 19.5 13.4 0.0014 18.5 13.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG36396.1 - 0.0015 18.8 15.5 0.0015 18.8 15.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 CEG36396.1 - 0.0024 17.6 11.7 0.0055 16.5 11.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CEG36396.1 - 0.0035 17.1 15.3 0.0097 15.7 15.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG36396.1 - 0.36 10.7 17.8 0.074 12.9 14.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG36396.1 - 0.52 10.4 12.0 1.2 9.3 12.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 CEG36396.1 - 0.74 10.0 9.8 1.4 9.1 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 CEG36396.1 - 1.4 9.0 9.6 0.57 10.3 6.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEG36396.1 - 5.8 7.3 16.8 0.55 10.6 11.2 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain HECT PF00632.25 CEG36397.1 - 3.1e-55 187.8 0.0 1.1e-54 186.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 CEG36397.1 - 4.6e-07 30.3 0.4 7.1e-05 23.3 0.0 2.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG36397.1 - 2.3e-06 28.0 0.5 0.0013 19.3 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG36397.1 - 0.00016 21.8 0.7 7.8 7.4 0.0 5.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CEG36397.1 - 0.044 14.3 0.2 15 6.2 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat eIF-3_zeta PF05091.12 CEG36397.1 - 0.08 11.9 1.3 0.14 11.1 1.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DENN PF02141.21 CEG36399.1 - 5.5e-37 127.5 2.9 2.2e-36 125.6 2.9 2.1 1 1 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 CEG36399.1 - 4.2e-11 43.1 0.6 0.00015 22.0 0.1 3.2 2 1 0 2 2 2 2 Regulator of G protein signaling domain uDENN PF03456.18 CEG36399.1 - 0.022 15.5 1.0 0.64 10.8 0.2 3.0 2 0 0 2 2 2 0 uDENN domain DUF2948 PF11164.8 CEG36399.1 - 0.026 14.6 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) dDENN PF03455.19 CEG36399.1 - 0.082 12.9 7.0 0.055 13.5 4.3 2.2 2 0 0 2 2 2 0 dDENN domain DUF2054 PF10218.9 CEG36399.1 - 0.094 12.8 0.4 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) SGS PF05002.15 CEG36400.1 - 1.2e-28 99.0 5.2 1.2e-28 99.0 5.2 2.3 3 0 0 3 3 3 1 SGS domain CS PF04969.16 CEG36400.1 - 3.7e-15 56.7 0.6 7e-15 55.8 0.6 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 CEG36400.1 - 3.8e-09 36.0 11.4 0.0044 16.8 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36400.1 - 2.8e-08 33.2 11.7 0.0034 17.4 0.0 4.2 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36400.1 - 1.1e-06 28.2 5.4 7e-06 25.6 0.4 3.4 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 CEG36400.1 - 0.00025 21.6 8.5 0.0022 18.6 1.2 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36400.1 - 0.00047 20.2 5.7 1.2 9.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36400.1 - 0.0006 20.3 5.1 0.034 14.6 2.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36400.1 - 0.0014 18.9 0.6 0.025 15.0 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG36400.1 - 0.0019 18.4 3.8 0.004 17.4 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4238 PF14022.6 CEG36400.1 - 0.047 13.2 0.5 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) DUF1735 PF08522.10 CEG36400.1 - 0.089 13.4 0.2 0.24 12.0 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1735) TPR_6 PF13174.6 CEG36400.1 - 0.092 13.4 2.6 0.8 10.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG36400.1 - 0.14 13.0 6.1 2.6 9.1 0.4 3.6 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36400.1 - 0.33 11.3 7.2 1 9.7 2.4 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Histone PF00125.24 CEG36401.1 - 3e-34 118.2 1.8 5.7e-34 117.3 1.8 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CEG36401.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CEG36401.1 - 0.0035 17.5 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CEG36401.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEG36401.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF2890 PF11081.8 CEG36401.1 - 0.12 12.4 9.0 0.19 11.8 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ank_4 PF13637.6 CEG36402.1 - 1.8e-11 44.3 0.0 1.2e-06 28.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG36402.1 - 4.7e-10 39.5 0.0 4.6e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG36402.1 - 8.1e-10 39.2 0.0 5e-09 36.6 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEG36402.1 - 1.8e-08 34.5 0.0 3.8e-06 27.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CEG36402.1 - 7e-08 32.2 0.0 1.1e-05 25.4 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat PAS PF00989.25 CEG36404.1 - 4.4e-136 445.5 5.6 7.6e-20 71.0 0.1 8.1 8 0 0 8 8 8 8 PAS fold PAS_4 PF08448.10 CEG36404.1 - 2.5e-96 317.4 0.0 4e-15 56.0 0.0 7.0 7 0 0 7 7 7 7 PAS fold PAS_9 PF13426.7 CEG36404.1 - 9.8e-85 279.6 17.7 2.9e-12 46.8 0.1 7.1 7 0 0 7 7 7 7 PAS domain PAS_3 PF08447.12 CEG36404.1 - 3.1e-47 158.8 0.0 1.1e-05 25.7 0.0 7.2 7 0 0 7 7 7 7 PAS fold PAS_8 PF13188.7 CEG36404.1 - 9.9e-24 82.9 1.3 0.0095 15.9 0.0 7.9 8 0 0 8 8 8 6 PAS domain PAS_10 PF13596.6 CEG36404.1 - 8.9e-16 58.4 12.9 0.00014 22.4 0.2 6.9 7 0 0 7 7 7 5 PAS domain PAS_7 PF12860.7 CEG36404.1 - 3.3e-10 40.1 22.4 0.13 12.4 0.2 9.1 7 6 0 7 7 7 4 PAS fold sCache_3_3 PF17202.4 CEG36404.1 - 0.00023 21.6 10.1 22 5.5 0.0 7.2 6 1 1 7 7 7 0 Single cache domain 3 DUF3189 PF11385.8 CEG36404.1 - 0.00056 19.8 0.4 6.4 6.6 0.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3189) MRP-L51 PF10244.9 CEG36404.1 - 0.0078 16.4 0.1 40 4.5 0.0 3.9 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit DUF5588 PF17826.1 CEG36404.1 - 0.089 11.7 4.3 21 3.9 0.0 4.7 6 0 0 6 6 6 0 Family of unknown function (DUF5588) Aminotran_5 PF00266.19 CEG36405.1 - 8.8e-32 110.5 0.0 1.3e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RnlB_antitoxin PF15933.5 CEG36405.1 - 0.046 14.0 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Antitoxin to bacterial toxin RNase LS or RnlA B12-binding PF02310.19 CEG36405.1 - 0.12 12.4 0.1 2.4 8.2 0.1 2.7 2 1 0 2 2 2 0 B12 binding domain Mce4_CUP1 PF11887.8 CEG36406.1 - 0.021 14.3 0.3 0.027 13.9 0.3 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative RXLR PF16810.5 CEG36406.1 - 2.4 8.6 5.9 5.8 7.3 5.9 1.8 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity PAS PF00989.25 CEG36408.1 - 4.4e-108 355.3 0.1 1.5e-23 82.9 0.0 6.1 6 0 0 6 6 6 6 PAS fold PAS_4 PF08448.10 CEG36408.1 - 9.5e-65 215.7 0.0 8.8e-13 48.5 0.0 6.1 6 0 0 6 6 6 6 PAS fold PAS_9 PF13426.7 CEG36408.1 - 3.6e-64 213.5 4.1 3.4e-12 46.5 0.2 6.1 6 0 0 6 6 6 6 PAS domain PAS_3 PF08447.12 CEG36408.1 - 5.2e-33 113.2 0.0 3.1e-07 30.6 0.0 6.2 6 0 0 6 6 6 6 PAS fold PAS_8 PF13188.7 CEG36408.1 - 1.9e-23 82.0 0.1 0.0033 17.4 0.0 6.4 6 0 0 6 6 6 5 PAS domain PAS_10 PF13596.6 CEG36408.1 - 2.5e-19 69.8 0.0 0.019 15.6 0.0 5.4 5 0 0 5 5 5 5 PAS domain PAS_7 PF12860.7 CEG36408.1 - 6.6e-09 36.0 2.5 1.9 8.6 0.0 8.1 6 4 0 6 6 6 2 PAS fold sCache_3_2 PF17203.4 CEG36408.1 - 0.23 11.6 3.4 40 4.3 0.0 4.5 4 1 0 4 4 4 0 Single cache domain 3 ABC_membrane PF00664.23 CEG36409.1 - 1.5e-84 283.9 32.5 4.8e-45 154.3 2.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG36409.1 - 2.4e-68 228.9 0.0 3e-34 118.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEG36409.1 - 9.9e-13 48.0 0.6 0.00014 21.4 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG36409.1 - 2.1e-08 33.8 0.2 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG36409.1 - 5.2e-07 30.0 0.9 0.027 14.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG36409.1 - 6.8e-07 29.8 1.9 0.023 15.1 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CEG36409.1 - 1.5e-06 27.6 0.0 0.0088 15.3 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin RsgA_GTPase PF03193.16 CEG36409.1 - 1.3e-05 25.2 0.1 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CEG36409.1 - 8.1e-05 22.4 0.3 0.49 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEG36409.1 - 8.2e-05 22.3 0.4 0.67 9.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 CEG36409.1 - 8.6e-05 21.5 1.5 0.2 10.4 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 CEG36409.1 - 0.00016 22.1 4.2 0.072 13.5 0.3 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 CEG36409.1 - 0.00017 21.7 2.8 2.3 8.5 0.3 4.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CEG36409.1 - 0.00019 21.4 0.3 3.1 7.5 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CEG36409.1 - 0.00074 19.5 0.8 0.68 9.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 CEG36409.1 - 0.00085 19.1 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CEG36409.1 - 0.0011 19.1 0.3 1.5 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 CEG36409.1 - 0.0013 18.0 0.0 0.51 9.5 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 CEG36409.1 - 0.0014 18.4 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 CEG36409.1 - 0.0022 17.9 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_18 PF13238.6 CEG36409.1 - 0.0023 18.5 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CEG36409.1 - 0.0037 17.4 2.7 0.85 9.7 0.1 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_7 PF12775.7 CEG36409.1 - 0.0037 16.8 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 CEG36409.1 - 0.0057 16.9 0.1 5.5 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CEG36409.1 - 0.01 15.6 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CEG36409.1 - 0.011 15.6 0.3 17 5.2 0.0 3.8 4 0 0 4 4 4 0 NTPase MMR_HSR1 PF01926.23 CEG36409.1 - 0.017 15.2 0.2 9.1 6.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 CEG36409.1 - 0.017 14.9 0.8 3.8 7.3 0.0 3.4 2 2 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 CEG36409.1 - 0.02 14.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 CEG36409.1 - 0.025 13.7 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 CEG36409.1 - 0.044 13.7 1.4 11 5.9 0.0 3.4 4 0 0 4 4 3 0 NACHT domain FtsL PF04999.13 CEG36409.1 - 0.061 13.3 0.0 0.38 10.8 0.0 2.5 1 0 0 1 1 1 0 Cell division protein FtsL LON_substr_bdg PF02190.16 CEG36409.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain RNA_helicase PF00910.22 CEG36409.1 - 0.11 12.9 0.1 9.5 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CEG36409.1 - 0.11 12.2 0.2 12 5.5 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEG36409.1 - 0.14 11.5 0.0 4.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CEG36409.1 - 0.14 12.6 0.1 13 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CEG36409.1 - 0.17 11.8 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 CEG36409.1 - 0.51 10.8 2.0 44 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain CLASP_N PF12348.8 CEG36410.1 - 1.7e-17 63.8 1.4 2.9e-17 63.0 1.4 1.4 1 0 0 1 1 1 1 CLASP N terminal DUF1538 PF07556.11 CEG36410.1 - 0.24 10.7 0.1 0.39 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) DUF16 PF01519.16 CEG36410.1 - 1.3 9.5 5.6 9.9 6.7 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 OmpH PF03938.14 CEG36410.1 - 2.5 8.5 4.8 0.9 9.9 1.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LRR_6 PF13516.6 CEG36411.1 - 1.6e-32 108.8 27.4 0.00051 19.9 0.0 11.7 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.7 CEG36411.1 - 4e-06 27.1 25.9 0.021 15.2 1.5 7.1 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG36411.1 - 0.0064 16.2 31.4 0.057 13.2 0.5 7.0 3 2 5 9 9 9 5 Leucine rich repeat LRR_1 PF00560.33 CEG36411.1 - 0.035 14.6 14.8 67 4.6 0.0 7.9 9 0 0 9 9 9 0 Leucine Rich Repeat PI-PLC-X PF00388.19 CEG36411.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Pentapeptide_4 PF13599.6 CEG36411.1 - 0.13 12.4 4.2 0.37 11.0 2.9 2.4 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Pkinase_Tyr PF07714.17 CEG36413.1 - 1e-39 136.4 0.0 6.8e-28 97.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG36413.1 - 1.9e-38 132.4 0.0 8.8e-29 100.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain STT3 PF02516.14 CEG36414.1 - 2.5e-90 303.8 31.6 1.1e-88 298.3 31.6 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit HAUS-augmin3 PF14932.6 CEG36415.1 - 0.00091 18.9 2.9 0.0011 18.7 2.9 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Snf7 PF03357.21 CEG36415.1 - 0.0069 16.0 2.6 0.0083 15.7 2.6 1.1 1 0 0 1 1 1 1 Snf7 Na_Ca_ex_C PF16494.5 CEG36415.1 - 0.013 16.0 1.3 0.016 15.7 1.3 1.1 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Prefoldin PF02996.17 CEG36415.1 - 0.015 15.2 1.2 0.015 15.2 1.2 1.5 2 0 0 2 2 2 0 Prefoldin subunit T2SSF PF00482.23 CEG36415.1 - 0.027 14.4 0.5 0.031 14.2 0.5 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CDC37_N PF03234.14 CEG36415.1 - 0.046 14.6 2.1 0.054 14.4 2.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Formin_GBD_N PF18382.1 CEG36415.1 - 0.048 14.1 1.1 0.06 13.8 1.1 1.1 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain HHH_6 PF14579.6 CEG36415.1 - 0.062 13.6 0.3 0.98 9.7 0.0 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF1664 PF07889.12 CEG36415.1 - 0.09 12.8 2.4 0.19 11.8 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FRB_dom PF08771.11 CEG36415.1 - 0.13 12.6 2.0 2.1 8.8 0.7 2.1 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Prominin PF05478.11 CEG36415.1 - 0.3 9.0 1.7 0.36 8.7 1.7 1.1 1 0 0 1 1 1 0 Prominin UPF0449 PF15136.6 CEG36415.1 - 0.47 11.0 3.7 1.3 9.6 2.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DASH_Dam1 PF08653.10 CEG36415.1 - 0.48 10.3 1.8 1.2 9.0 0.5 2.1 1 1 1 2 2 2 0 DASH complex subunit Dam1 DFRP_C PF16543.5 CEG36416.1 - 5.6e-20 71.6 0.3 5.6e-20 71.6 0.3 4.1 3 2 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 CEG36416.1 - 1.6e-05 24.7 0.9 1.6e-05 24.7 0.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG36416.1 - 4.2e-05 23.4 5.2 4.2e-05 23.4 5.2 2.9 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEG36416.1 - 0.00011 21.8 9.0 0.00067 19.4 2.1 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 CEG36416.1 - 0.00099 19.8 19.4 0.0011 19.6 5.9 4.0 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 CEG36416.1 - 0.2 12.2 8.6 0.37 11.3 2.7 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CEG36416.1 - 0.64 10.3 10.7 0.11 12.7 1.2 3.3 2 1 2 4 4 4 0 Zinc-finger containing family DUF220 PF02713.14 CEG36417.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF220 DNA_ligase_A_M PF01068.21 CEG36418.1 - 3.9e-35 121.4 0.1 1.5e-34 119.4 0.1 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 CEG36418.1 - 1.7e-22 79.9 0.0 3.9e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 CEG36418.1 - 3.8e-20 72.9 0.1 7.6e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus GAF_2 PF13185.6 CEG36418.1 - 6.3e-05 23.3 0.0 0.00019 21.7 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 CEG36418.1 - 0.0018 18.9 0.0 0.0063 17.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain DNA_ligase_OB_2 PF14743.6 CEG36418.1 - 0.0049 16.9 2.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 DNA ligase OB-like domain LSM PF01423.22 CEG36419.1 - 8.4e-13 47.8 0.0 1.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEG36419.1 - 0.00016 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain RhoGAP PF00620.27 CEG36420.1 - 3.4e-16 59.4 0.1 5.7e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain UPF0552 PF10574.9 CEG36420.1 - 0.0035 16.7 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin PH_8 PF15409.6 CEG36420.1 - 0.0077 16.5 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CEG36420.1 - 0.008 16.7 3.3 0.024 15.2 0.5 2.8 2 1 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 CEG36421.1 - 6.4e-49 166.6 0.0 1.5e-48 165.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG36421.1 - 1.9e-39 135.7 0.0 3.6e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Chorion_2 PF03964.15 CEG36421.1 - 0.64 10.9 5.9 1.7 9.5 5.9 1.7 1 0 0 1 1 1 0 Chorion family 2 TauD PF02668.16 CEG36422.1 - 1.1e-35 123.7 0.0 1.7e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CEG36422.1 - 1.7e-11 44.6 0.3 2.9e-10 40.7 0.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 CEG36422.1 - 4.7e-05 22.7 0.2 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 CsiD IL17 PF06083.11 CEG36422.1 - 0.0058 17.1 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Interleukin-17 Ferric_reduct PF01794.19 CEG36423.1 - 1.9e-17 63.5 15.7 1.9e-17 63.5 15.7 3.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG36423.1 - 4e-14 53.0 0.0 7.5e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG36423.1 - 7.6e-11 42.1 0.1 3.5e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Aminotran_5 PF00266.19 CEG36424.1 - 5.4e-32 111.2 0.0 7.5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEG36424.1 - 0.072 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Ferric_reduct PF01794.19 CEG36425.1 - 1.3e-18 67.3 13.1 1.3e-18 67.3 13.1 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG36425.1 - 7.5e-15 55.4 0.0 1.6e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG36425.1 - 1.7e-12 47.3 0.0 1e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Csm1 PF12539.8 CEG36428.1 - 0.008 16.8 0.0 0.024 15.2 0.0 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Ribosomal_L3 PF00297.22 CEG36429.1 - 7.7e-179 594.4 8.8 8.7e-179 594.2 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PCIF1_WW PF12237.8 CEG36430.1 - 1e-65 220.6 0.2 1.6e-65 219.9 0.2 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF3924 PF13062.6 CEG36430.1 - 0.12 12.3 0.0 23 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) DUF645 PF04875.12 CEG36430.1 - 0.12 12.4 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF645 SMC_N PF02463.19 CEG36431.1 - 1.1e-65 221.1 1.8 4e-64 216.1 1.8 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEG36431.1 - 1e-25 90.3 0.2 4.1e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CEG36431.1 - 7.4e-10 39.1 9.1 1.2e-05 25.2 0.0 3.7 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEG36431.1 - 3.5e-07 30.3 17.6 3.5e-07 30.3 17.6 4.5 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CEG36431.1 - 0.002 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 CEG36431.1 - 0.0032 18.0 16.3 0.0032 18.0 16.3 8.4 4 2 4 8 8 8 1 Apg6 coiled-coil region AAA_23 PF13476.6 CEG36431.1 - 0.46 11.0 111.2 0.0094 16.5 55.9 6.4 3 2 1 4 4 4 0 AAA domain RVT_1 PF00078.27 CEG36432.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YokU PF14122.6 CEG36439.1 - 0.015 15.3 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin Caskin-tail PF16632.5 CEG36439.1 - 0.044 14.2 0.9 2.2 8.7 0.2 2.5 2 0 0 2 2 2 0 C-terminal region of Caskin Bromodomain PF00439.25 CEG36441.1 - 1.3e-20 73.2 0.1 2.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Bromodomain COBRA1 PF06209.13 CEG36441.1 - 1.9e-14 53.4 3.3 1.6e-07 30.6 1.5 3.6 3 1 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) Acetyltransf_1 PF00583.25 CEG36442.1 - 7.4e-16 58.4 0.1 1e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG36442.1 - 1.3e-08 34.9 0.4 1.7e-08 34.4 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG36442.1 - 1.7e-08 34.8 0.1 2.7e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG36442.1 - 2.2e-07 30.7 0.1 3.5e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CEG36442.1 - 0.013 16.1 0.1 0.018 15.7 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEG36442.1 - 0.022 14.8 0.1 0.04 14.0 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CEG36442.1 - 0.11 12.4 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase IQ PF00612.27 CEG36443.1 - 1.1e-07 31.0 18.0 0.011 15.4 0.1 5.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif CEBP_ZZ PF16366.5 CEG36443.1 - 0.0049 17.1 4.8 0.013 15.7 4.8 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain MpPF1 PF07668.11 CEG36443.1 - 0.01 15.2 1.3 0.024 13.9 1.3 1.6 1 0 0 1 1 1 0 M penetrans paralogue family 1 zf-B_box PF00643.24 CEG36443.1 - 0.015 15.4 5.8 0.032 14.4 5.8 1.5 1 0 0 1 1 1 0 B-box zinc finger Focal_AT PF03623.13 CEG36443.1 - 3.6 7.6 9.4 0.36 10.8 2.8 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region C2 PF00168.30 CEG36444.1 - 3.4e-09 36.9 0.0 3.5e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain NUT PF12881.7 CEG36444.1 - 0.6 8.5 10.0 1.2 7.4 10.0 1.4 1 0 0 1 1 1 0 NUT protein DDE_1 PF03184.19 CEG36445.1 - 7.8e-13 48.5 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DnaJ PF00226.31 CEG36447.1 - 0.00017 21.6 0.0 0.0007 19.7 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain IMS PF00817.20 CEG36447.1 - 0.098 12.6 5.9 1.6 8.7 3.6 2.5 2 0 0 2 2 2 0 impB/mucB/samB family Hemagglutinin PF00509.18 CEG36447.1 - 0.18 10.1 1.6 0.34 9.2 1.6 1.6 1 0 0 1 1 1 0 Haemagglutinin DUF948 PF06103.11 CEG36447.1 - 1.4 9.3 3.4 2.6 8.4 1.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CEG36447.1 - 8.8 6.9 11.9 1.3 9.6 0.4 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Calx-beta PF03160.14 CEG36448.1 - 4.7e-21 74.8 0.0 0.00086 19.4 0.0 4.9 5 0 0 5 5 5 4 Calx-beta domain TNFR_c6 PF00020.18 CEG36448.1 - 2.5e-11 43.8 38.8 1.1e-06 28.9 7.3 5.7 2 1 4 6 6 6 4 TNFR/NGFR cysteine-rich region DUF4843 PF16132.5 CEG36448.1 - 0.04 13.5 0.1 2.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4843) Methyltransf_16 PF10294.9 CEG36449.1 - 3.9e-18 65.8 0.0 6.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Borrelia_P13 PF05628.12 CEG36449.1 - 0.18 11.8 0.0 1.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Borrelia membrane protein P13 Peptidase_C50 PF03568.17 CEG36450.1 - 4.9e-64 216.9 0.0 3.3e-63 214.2 0.0 2.4 1 1 0 1 1 1 1 Peptidase family C50 SAP PF02037.27 CEG36450.1 - 0.00013 21.7 0.8 0.00038 20.1 0.8 1.9 1 0 0 1 1 1 1 SAP domain TPR_2 PF07719.17 CEG36450.1 - 0.0032 17.5 0.1 3.4 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat CHAT PF12770.7 CEG36450.1 - 0.015 14.8 0.1 0.084 12.3 0.0 2.1 2 0 0 2 2 2 0 CHAT domain Arm_vescicular PF18770.1 CEG36450.1 - 0.11 12.4 0.7 0.59 10.1 0.7 2.3 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor DUF725 PF05267.12 CEG36450.1 - 0.51 10.3 6.6 0.17 11.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF725) BPL_LplA_LipB PF03099.19 CEG36451.1 - 4.5e-12 46.0 0.1 6.3e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ADH_N_assoc PF13823.6 CEG36451.1 - 0.91 9.5 3.2 3.1 7.8 1.1 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Flavoprotein PF02441.19 CEG36452.1 - 1.9e-43 147.9 0.0 2.3e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Prenyltrans PF00432.21 CEG36456.1 - 5.6e-20 70.8 8.1 2.7e-08 33.4 0.1 6.2 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat RICTOR_N PF14664.6 CEG36456.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF1279 PF06916.13 CEG36457.1 - 4e-11 43.3 0.1 6.2e-11 42.7 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) RabGAP-TBC PF00566.18 CEG36459.1 - 9.5e-23 81.0 0.4 1.2e-22 80.7 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UVR PF02151.19 CEG36460.1 - 1.4e-11 43.7 15.8 2.1e-06 27.3 3.1 2.4 2 0 0 2 2 2 2 UvrB/uvrC motif PspA_IM30 PF04012.12 CEG36460.1 - 0.0079 15.8 7.6 0.011 15.4 7.6 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF4140 PF13600.6 CEG36460.1 - 0.36 11.3 5.3 0.37 11.2 4.6 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pcc1 PF09341.10 CEG36461.1 - 4.9e-17 61.8 0.2 8.9e-17 61.0 0.2 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 PRTase_3 PF15610.6 CEG36462.1 - 0.13 11.4 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 PRTase ComF-like P22_CoatProtein PF11651.8 CEG36463.1 - 0.13 10.9 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 PSD2 PF07624.11 CEG36465.1 - 0.0016 18.2 2.7 0.8 9.5 0.5 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1585) VWD PF00094.25 CEG36465.1 - 3.7 7.8 4.7 1.2 9.3 1.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type D domain tRNA-synt_1e PF01406.19 CEG36466.1 - 6.4e-107 357.4 0.8 1.2e-106 356.4 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CEG36466.1 - 4.4e-11 42.2 0.3 4.9e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEG36466.1 - 9.8e-05 20.8 0.0 0.0095 14.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CEG36466.1 - 0.0041 16.0 0.0 0.013 14.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 CEG36466.1 - 0.0079 16.7 0.1 0.024 15.1 0.1 1.8 1 0 0 1 1 1 1 DALR domain PAP_PilO PF06864.12 CEG36467.1 - 0.0065 15.4 0.0 0.0097 14.8 0.0 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) HIG_1_N PF04588.13 CEG36467.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region KIX_2 PF16987.5 CEG36469.1 - 3.4e-06 27.0 0.2 3.4e-06 27.0 0.2 2.7 2 1 1 3 3 3 1 KIX domain Csa1 PF06023.12 CEG36469.1 - 0.14 11.5 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 FYVE PF01363.21 CEG36470.1 - 1.4e-14 54.0 15.8 3.2e-14 52.8 15.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger SPX PF03105.19 CEG36470.1 - 5.3 6.9 8.7 5.4 6.8 2.1 2.1 2 0 0 2 2 2 0 SPX domain KIX_2 PF16987.5 CEG36473.1 - 1.4e-06 28.2 0.1 4.7e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 KIX domain DUF1041 PF06292.17 CEG36473.1 - 0.009 16.4 0.6 0.021 15.2 0.4 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) EloA-BP1 PF15870.5 CEG36473.1 - 0.0097 16.2 0.5 0.017 15.4 0.5 1.5 1 1 0 1 1 1 1 ElonginA binding-protein 1 TsaE PF02367.17 CEG36475.1 - 5.1e-32 110.5 0.0 6.9e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CEG36475.1 - 0.00085 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CEG36475.1 - 0.001 19.5 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 CEG36475.1 - 0.0023 17.1 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 CEG36475.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 CEG36475.1 - 0.017 14.3 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CEG36475.1 - 0.024 14.2 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEG36475.1 - 0.03 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 CEG36475.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CEG36475.1 - 0.047 14.0 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEG36475.1 - 0.047 14.1 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AFG1_ATPase PF03969.16 CEG36475.1 - 0.065 12.1 0.1 0.13 11.2 0.0 1.5 1 1 1 2 2 2 0 AFG1-like ATPase AAA PF00004.29 CEG36475.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEG36475.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ufd2P_core PF10408.9 CEG36476.1 - 3.4e-162 541.3 3.4 5.8e-162 540.5 3.4 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CEG36476.1 - 1.5e-30 105.1 0.5 4.7e-30 103.6 0.5 1.9 1 0 0 1 1 1 1 U-box domain Med9 PF07544.13 CEG36476.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TGase_elicitor PF16683.5 CEG36480.1 - 1.4e-29 103.0 0.1 1.6e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor IQ PF00612.27 CEG36481.1 - 2.5e-08 33.0 22.0 0.05 13.4 2.2 5.4 4 0 0 4 4 4 4 IQ calmodulin-binding motif DUF3670 PF12419.8 CEG36481.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein NifU_N PF01592.16 CEG36482.1 - 0.15 12.2 0.0 0.16 12.1 0.0 1.0 1 0 0 1 1 1 0 NifU-like N terminal domain Kinesin PF00225.23 CEG36488.1 - 9.9e-82 274.5 0.8 1.7e-81 273.8 0.8 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG36488.1 - 8.2e-35 119.9 0.0 1.8e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding CREPT PF16566.5 CEG36488.1 - 0.042 14.0 4.2 0.12 12.6 4.2 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS6_N PF14661.6 CEG36488.1 - 0.78 9.3 5.3 1.7 8.2 5.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF87 PF01935.17 CEG36488.1 - 1.2 9.2 4.9 1.2 9.2 0.2 3.0 3 1 0 3 3 3 0 Helicase HerA, central domain FH2 PF02181.23 CEG36489.1 - 7.7e-80 268.8 5.7 1.4e-79 268.0 5.7 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG36489.1 - 2.6e-42 144.9 16.7 3.9e-12 46.8 0.1 6.3 6 0 0 6 6 6 4 Subunit CCDC53 of WASH complex zf-PHD-like PF15446.6 CEG36489.1 - 0.00076 19.1 2.1 0.0029 17.3 2.1 2.1 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD PF00628.29 CEG36489.1 - 0.002 18.0 3.9 0.006 16.5 3.9 1.9 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 CEG36489.1 - 0.015 15.4 1.1 0.044 13.9 1.1 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 CEG36489.1 - 0.26 11.2 4.0 0.1 12.5 0.7 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CEG36489.1 - 0.63 10.2 2.3 1.1 9.4 0.9 2.2 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 CEG36489.1 - 1.6 9.0 5.4 0.33 11.2 0.8 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain DHR10 PF18595.1 CEG36489.1 - 4.6 7.3 9.0 0.34 11.0 1.9 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain UPF0193 PF05250.11 CEG36490.1 - 6.7e-08 32.6 1.0 1e-07 32.0 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) APH_6_hur PF04655.14 CEG36490.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase GrpE PF01025.19 CEG36490.1 - 0.012 15.3 0.3 0.016 14.9 0.3 1.3 1 0 0 1 1 1 0 GrpE MalF_P2 PF14785.6 CEG36490.1 - 0.42 10.6 1.7 0.83 9.7 0.2 1.9 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain KIAA1430 PF13879.6 CEG36496.1 - 0.0013 19.5 6.2 0.0013 19.5 6.2 4.2 2 1 0 3 3 3 1 KIAA1430 homologue HypA PF01155.19 CEG36496.1 - 0.018 15.0 0.6 0.018 15.0 0.6 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATG16 PF08614.11 CEG36496.1 - 7.1 6.8 66.4 1.4 9.1 23.9 4.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PH PF00169.29 CEG36497.1 - 3.9e-19 69.1 9.0 5.4e-09 36.5 0.3 5.8 4 4 0 4 4 4 3 PH domain PH_8 PF15409.6 CEG36497.1 - 0.0013 19.0 3.0 0.02 15.2 0.2 3.8 5 0 0 5 5 5 1 Pleckstrin homology domain PH_17 PF18012.1 CEG36497.1 - 0.036 13.8 0.1 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 CEG36497.1 - 0.21 12.0 14.2 6.5 7.2 0.8 5.0 5 2 1 6 6 6 0 Pleckstrin homology domain GYF_2 PF14237.6 CEG36499.1 - 8.7e-21 73.5 1.1 1.4e-09 37.6 0.1 3.0 2 0 0 2 2 2 2 GYF domain 2 RRM_1 PF00076.22 CEG36499.1 - 3.9e-13 49.0 0.1 1.5e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG36499.1 - 0.002 18.1 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEG36499.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF1866 PF08952.11 CEG36499.1 - 0.0085 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 CEG36499.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SCVP PF17619.2 CEG36499.1 - 0.39 11.6 2.0 2.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Secreted clade V proteins MoaE PF02391.17 CEG36500.1 - 6.8e-39 132.6 0.1 1.1e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 MoaE protein CEP19 PF14933.6 CEG36500.1 - 2.9e-14 53.7 0.5 6.6e-14 52.6 0.5 1.6 1 1 0 1 1 1 1 CEP19-like protein DUF982 PF06169.12 CEG36500.1 - 0.052 13.6 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF982) DciA PF05258.12 CEG36500.1 - 0.093 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA DUF2423 PF10338.9 CEG36501.1 - 5.2e-10 39.4 4.4 5.2e-10 39.4 4.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 CEG36501.1 - 0.6 10.7 11.6 2.6 8.6 11.6 2.0 1 1 0 1 1 1 0 Learning-associated protein PB1 PF00564.24 CEG36504.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 PB1 domain Myb_DNA-binding PF00249.31 CEG36504.1 - 0.015 15.5 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Myb-like DNA-binding domain Fer4_14 PF13394.6 CEG36504.1 - 0.092 12.9 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain HupH_C PF04809.13 CEG36504.1 - 0.17 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Kelch_3 PF13415.6 CEG36505.1 - 7.4e-10 38.9 1.2 1.2e-08 35.1 0.1 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CEG36505.1 - 1.4e-08 34.6 0.0 3.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG36505.1 - 7.5e-07 29.2 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CEG36505.1 - 2.7e-06 27.2 0.1 2.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 CEG36505.1 - 6.5e-06 25.6 0.0 1.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CEG36505.1 - 2.8e-05 23.9 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Nkap_C PF06047.11 CEG36506.1 - 3.3e-48 162.0 2.2 5.1e-48 161.4 2.2 1.3 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain ACOX PF01756.19 CEG36507.1 - 9e-37 126.4 0.0 1.5e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEG36507.1 - 3.8e-12 46.8 9.8 3.6e-11 43.7 1.2 2.4 1 1 1 2 2 2 2 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEG36507.1 - 3.6e-10 39.9 0.0 8.7e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEG36507.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 CEG36508.1 - 2.2e-72 243.6 0.0 2.9e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36508.1 - 4.7e-32 111.3 0.0 6.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG36508.1 - 0.016 15.1 0.1 0.56 10.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG36508.1 - 0.097 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1754 PF08555.10 CEG36510.1 - 0.0039 17.9 19.2 0.46 11.3 19.2 2.4 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Baculo_LEF5_C PF11792.8 CEG36510.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain GAS PF13851.6 CEG36510.1 - 0.91 8.8 14.0 2.5 7.4 14.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribosomal_L37 PF08561.10 CEG36510.1 - 4.5 7.8 9.9 5.7 7.5 9.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 SAS-6_N PF16531.5 CEG36512.1 - 1.5e-30 105.6 0.1 1.5e-30 105.6 0.1 3.1 2 1 0 2 2 2 1 Centriolar protein SAS N-terminal adh_short_C2 PF13561.6 CEG36513.1 - 1.1e-53 182.2 2.6 1.2e-53 182.1 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG36513.1 - 1.1e-45 155.5 2.3 1.4e-45 155.2 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG36513.1 - 6.6e-11 42.4 1.2 9.9e-11 41.9 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG36513.1 - 0.0013 18.2 0.3 0.0027 17.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.20 CEG36513.1 - 0.01 15.9 0.6 0.034 14.2 0.0 2.1 2 1 1 3 3 3 0 Glycosyltransferase family 28 N-terminal domain F420_oxidored PF03807.17 CEG36513.1 - 0.031 14.8 0.9 0.076 13.6 0.0 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CEG36513.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CEG36513.1 - 0.35 10.7 3.6 0.68 9.8 3.6 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Lactonase PF10282.9 CEG36514.1 - 2.1e-71 241.0 0.1 2.6e-71 240.7 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF5575 PF17738.1 CEG36515.1 - 0.0019 17.3 0.4 1.2 8.1 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5575) SWIM PF04434.17 CEG36515.1 - 0.12 12.0 1.5 0.27 11.0 1.5 1.5 1 0 0 1 1 1 0 SWIM zinc finger Porin_3 PF01459.22 CEG36516.1 - 3.7e-11 43.0 0.7 5.6e-11 42.4 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic porin DUF4567 PF15131.6 CEG36516.1 - 0.07 13.2 0.4 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) DEAD PF00270.29 CEG36517.1 - 2e-48 164.5 0.0 2.8e-47 160.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG36517.1 - 1.3e-32 112.4 0.1 4.1e-32 110.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EMP24_GP25L PF01105.24 CEG36518.1 - 2.1e-26 93.0 0.1 2.5e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cyclin_N PF00134.23 CEG36519.1 - 5.6e-08 32.6 0.2 5.6e-08 32.6 0.2 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain NIF PF03031.18 CEG36520.1 - 2e-47 160.9 0.0 3.1e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Q_salvage PF10343.9 CEG36521.1 - 2.7e-80 270.0 0.0 4.6e-80 269.2 0.0 1.4 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DHC_N1 PF08385.12 CEG36522.1 - 7.6e-183 609.2 15.0 7.6e-183 609.2 15.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG36522.1 - 2e-143 477.3 0.0 1.9e-142 474.0 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG36522.1 - 1.6e-112 376.6 16.2 1.6e-112 376.6 16.2 3.9 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG36522.1 - 7.2e-84 281.6 0.0 2.7e-83 279.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CEG36522.1 - 6.7e-77 258.3 2.5 1.3e-74 250.8 0.2 3.3 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CEG36522.1 - 7.8e-77 257.3 3.0 3.9e-75 251.7 0.3 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG36522.1 - 1.2e-59 200.9 1.3 1.8e-54 184.0 0.0 4.3 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG36522.1 - 1.3e-48 164.9 0.0 3.1e-48 163.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG36522.1 - 5.1e-38 131.0 9.1 1e-37 130.0 9.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG36522.1 - 5.9e-38 129.6 0.6 5.7e-37 126.4 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG36522.1 - 2.1e-20 73.1 0.0 1.1e-19 70.8 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG36522.1 - 8.2e-15 54.8 2.0 1.4e-13 50.9 0.2 3.8 2 1 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CEG36522.1 - 5.1e-13 49.2 0.1 6.6e-05 22.9 0.0 5.8 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CEG36522.1 - 9.2e-09 35.8 1.7 0.39 11.1 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG36522.1 - 1.8e-05 25.2 1.3 8.3 6.8 0.0 5.8 6 0 0 6 6 5 0 AAA ATPase domain AAA_22 PF13401.6 CEG36522.1 - 2.4e-05 24.6 1.8 2.9 8.2 0.0 5.5 4 1 1 5 5 5 1 AAA domain DUF3583 PF12126.8 CEG36522.1 - 0.002 17.6 0.1 0.0083 15.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) AAA_18 PF13238.6 CEG36522.1 - 0.0044 17.5 0.1 4.9 7.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CEG36522.1 - 0.033 13.9 0.2 1.4 8.7 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CEG36522.1 - 0.034 14.3 0.3 22 5.2 0.0 3.7 4 0 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 CEG36522.1 - 0.14 12.6 0.8 17 5.9 0.0 3.8 3 0 0 3 3 3 0 RNA helicase Erythro-docking PF09277.11 CEG36522.1 - 0.18 11.7 0.4 3 7.8 0.0 3.0 3 0 0 3 3 3 0 Erythronolide synthase, docking AAA_19 PF13245.6 CEG36522.1 - 0.33 11.3 4.5 61 3.9 0.0 4.3 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CEG36522.1 - 0.81 9.7 3.2 10 6.1 0.1 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SLX9 PF15341.6 CEG36523.1 - 1.8e-14 54.3 10.2 1.8e-14 54.3 10.2 2.2 3 0 0 3 3 3 1 Ribosome biogenesis protein SLX9 Trypsin PF00089.26 CEG36524.1 - 1.1e-49 169.2 0.2 1.4e-49 168.9 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG36524.1 - 5.4e-07 30.6 0.1 7.9e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CEG36524.1 - 0.02 14.4 0.0 1.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Chymotrypsin family Peptidase-S1 SGT1 PF07093.11 CEG36525.1 - 2e-92 310.5 9.2 1.1e-74 252.0 0.1 2.1 1 1 1 2 2 2 2 SGT1 protein Kelch_4 PF13418.6 CEG36526.1 - 4e-32 110.0 0.7 1.9e-06 27.8 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CEG36526.1 - 9.5e-24 83.2 8.5 1.1e-05 25.6 0.0 7.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG36526.1 - 2.3e-22 78.5 0.3 6.3e-05 23.1 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CEG36526.1 - 8.5e-21 73.5 0.7 0.00012 21.9 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 CEG36526.1 - 3.4e-15 55.3 0.0 0.00057 19.4 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CEG36526.1 - 3.6e-10 39.4 1.7 1.2 9.2 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Uds1 PF15456.6 CEG36526.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.8 3 1 1 4 4 4 0 Up-regulated During Septation Ribosomal_L9_N PF01281.19 CEG36526.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Yuri_gagarin PF15934.5 CEG36526.1 - 0.2 11.5 9.4 0.4 10.5 9.4 1.4 1 0 0 1 1 1 0 Yuri gagarin Tropomyosin_1 PF12718.7 CEG36526.1 - 0.37 10.9 13.7 3.8 7.6 0.9 2.5 2 0 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 CEG36526.1 - 2.1 8.9 14.5 6.4 7.3 0.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 CEG36526.1 - 4.6 7.8 8.8 40 4.8 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 CEG36526.1 - 5.6 6.3 18.8 0.85 8.9 9.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding A_deaminase PF00962.22 CEG36527.1 - 1.4e-107 359.8 0.0 6.2e-107 357.7 0.0 2.0 2 1 0 2 2 2 1 Adenosine/AMP deaminase Aminotran_3 PF00202.21 CEG36528.1 - 2e-116 389.0 0.0 2.3e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CEG36528.1 - 0.035 13.3 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SMC_N PF02463.19 CEG36529.1 - 4.9e-27 94.8 5.3 2e-26 92.8 5.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG36529.1 - 1.5e-10 41.9 36.5 1.5e-10 41.9 36.5 6.1 3 2 0 3 3 1 1 AAA domain AAA_15 PF13175.6 CEG36529.1 - 3.7e-09 36.8 6.7 3.7e-09 36.8 6.7 3.3 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 CEG36529.1 - 9.8e-05 22.0 0.0 0.0003 20.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CEG36529.1 - 0.00076 19.4 0.1 0.00076 19.4 0.1 3.7 4 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Atg14 PF10186.9 CEG36529.1 - 0.0061 15.7 2.7 0.0061 15.7 2.7 5.6 2 2 3 5 5 4 2 Vacuolar sorting 38 and autophagy-related subunit 14 Toprim_4 PF13662.6 CEG36529.1 - 0.039 14.4 0.2 0.22 12.0 0.2 2.3 1 0 0 1 1 1 0 Toprim domain Fez1 PF06818.15 CEG36529.1 - 0.42 11.1 90.1 0.02 15.4 8.3 5.7 2 2 2 4 4 4 0 Fez1 UvrA_DNA-bind PF17755.1 CEG36529.1 - 0.5 10.7 0.0 0.5 10.7 0.0 3.3 2 1 0 3 3 3 0 UvrA DNA-binding domain AAA_16 PF13191.6 CEG36529.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.6 4 2 0 4 4 3 0 AAA ATPase domain HisKA PF00512.25 CEG36529.1 - 2.2 8.4 8.3 0.23 11.5 0.7 3.3 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Nucleoside_tran PF01733.18 CEG36531.1 - 3.3e-31 108.8 11.6 2.8e-30 105.8 11.6 2.1 1 1 0 1 1 1 1 Nucleoside transporter Gram_pos_anchor PF00746.21 CEG36531.1 - 0.056 13.4 0.4 0.056 13.4 0.4 3.4 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Corona_3 PF04694.12 CEG36531.1 - 0.15 12.4 0.4 0.55 10.6 0.4 2.0 1 1 0 1 1 1 0 Coronavirus ORF3 protein Ufd2P_core PF10408.9 CEG36532.1 - 4e-24 85.2 1.4 5.4e-21 74.9 0.5 2.9 2 1 0 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 CEG36532.1 - 4.5e-21 74.8 0.0 1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain ZZ PF00569.17 CEG36532.1 - 3.5e-06 26.7 13.0 3.5e-06 26.7 13.0 3.9 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_2 PF03107.16 CEG36532.1 - 0.00022 21.5 4.5 0.00022 21.5 4.5 3.6 3 0 0 3 3 3 2 C1 domain Phasin_2 PF09361.10 CEG36532.1 - 0.13 12.6 0.6 0.44 10.8 0.6 1.9 1 0 0 1 1 1 0 Phasin protein Proteasome PF00227.26 CEG36533.1 - 4.1e-49 166.6 0.0 5.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEG36533.1 - 3.3e-14 52.3 0.1 5.7e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 CEG36533.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Kinesin PF00225.23 CEG36535.1 - 2.9e-98 328.9 0.3 2.9e-98 328.9 0.3 2.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEG36535.1 - 9.9e-48 161.9 4.8 1.4e-47 161.3 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding Spt46 PF17734.1 CEG36535.1 - 0.29 10.9 3.0 0.89 9.3 0.4 2.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 FYVE PF01363.21 CEG36536.1 - 2.7e-19 69.1 9.0 3.7e-19 68.6 9.0 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG36536.1 - 0.013 15.8 9.6 0.04 14.1 9.7 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 CEG36536.1 - 0.42 10.5 7.6 0.56 10.1 4.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEG36536.1 - 0.78 10.1 9.7 1.2 9.5 4.9 2.2 2 0 0 2 2 2 0 C1 domain UPRTase PF14681.6 CEG36537.1 - 2.7e-70 236.0 0.0 3.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CEG36537.1 - 1e-05 25.1 0.5 2e-05 24.1 0.5 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF3263 PF11662.8 CEG36537.1 - 0.088 12.7 0.2 6.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) adh_short PF00106.25 CEG36538.1 - 8.9e-21 74.2 0.0 3.4e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEG36538.1 - 8e-18 64.9 0.0 6.7e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Zn-ribbon_8 PF09723.10 CEG36538.1 - 0.079 13.1 1.3 0.24 11.6 1.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DUF1776 PF08643.10 CEG36538.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NFACT-C PF11923.8 CEG36544.1 - 2.2e-08 34.0 7.0 4.9e-08 32.8 0.0 2.9 2 1 1 3 3 3 1 NFACT protein C-terminal domain EOS1 PF12326.8 CEG36544.1 - 1.8 8.5 4.6 0.51 10.3 0.4 1.8 1 1 1 2 2 2 0 N-glycosylation protein Pro_Al_protease PF02983.14 CEG36547.1 - 0.081 13.0 1.8 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain WD40 PF00400.32 CEG36548.1 - 2.4e-11 44.0 8.8 0.0003 21.5 0.1 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CEG36548.1 - 0.00027 20.0 0.2 0.034 13.1 0.1 2.3 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M24 PF00557.24 CEG36549.1 - 1.6e-48 165.1 0.0 2.2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CEG36549.1 - 2.8e-17 62.8 6.0 6e-17 61.7 6.0 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CEG36549.1 - 0.0037 17.3 3.6 0.0093 16.0 3.6 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 CEG36549.1 - 1.6 8.6 6.2 3.4 7.6 6.2 1.5 1 0 0 1 1 1 0 HIT zinc finger SWIB PF02201.18 CEG36550.1 - 5.5e-16 58.2 0.0 1.6e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C2HC_2 PF13913.6 CEG36550.1 - 3.1e-12 46.1 18.8 1.1e-07 31.6 4.1 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type FYVE PF01363.21 CEG36550.1 - 0.04 14.1 0.1 0.04 14.1 0.1 2.9 3 0 0 3 3 3 0 FYVE zinc finger zf-RING_7 PF02591.15 CEG36550.1 - 0.15 12.3 4.4 3.4 7.9 0.1 3.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C2H2 PF00096.26 CEG36550.1 - 0.32 11.5 16.4 0.74 10.4 2.0 4.3 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG36550.1 - 3.8 8.6 19.0 2.5 9.2 0.9 4.5 3 1 1 4 4 4 0 C2H2-type zinc finger efThoc1 PF11957.8 CEG36553.1 - 2.8e-104 349.5 0.1 3.5e-104 349.2 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor ABM PF03992.16 CEG36553.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Mcp5_PH PF12814.7 CEG36556.1 - 0.09 12.9 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology zf-UBR PF02207.20 CEG36557.1 - 4e-20 71.7 9.9 4e-20 71.7 9.9 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Mei4 PF13971.6 CEG36557.1 - 0.0093 15.5 0.5 0.84 9.1 0.0 2.8 3 0 0 3 3 3 2 Meiosis-specific protein Mei4 Pkinase_Tyr PF07714.17 CEG36558.1 - 5e-28 98.1 0.0 7.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG36558.1 - 2.9e-20 72.7 0.0 4.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Laminin_G_3 PF13385.6 CEG36558.1 - 9.6e-07 29.1 0.0 2.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PDZ_6 PF17820.1 CEG36558.1 - 0.00015 21.5 0.1 0.00037 20.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG36558.1 - 0.0078 16.6 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 CEG36558.1 - 0.028 14.3 0.0 0.028 14.3 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG36558.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_2 PF07727.14 CEG36563.1 - 1.5e-05 24.8 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1077 PF06417.12 CEG36563.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) LRR_4 PF12799.7 CEG36564.1 - 2.6e-15 56.3 19.7 9.1e-08 32.3 2.3 3.5 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG36564.1 - 2.7e-14 53.0 2.6 4.6e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CEG36564.1 - 2e-09 37.1 13.2 0.00031 20.4 3.8 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CEG36564.1 - 0.82 9.9 6.0 17 5.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat NAD_binding_2 PF03446.15 CEG36565.1 - 3.7e-52 176.7 0.2 5.9e-52 176.0 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEG36565.1 - 8.9e-30 103.4 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CEG36565.1 - 2.4e-08 33.6 0.1 4.7e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CEG36565.1 - 1.5e-06 28.6 0.0 5.6e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CEG36565.1 - 1.7e-06 28.0 0.2 8.3e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CEG36565.1 - 5.8e-06 26.0 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CEG36565.1 - 0.00042 20.5 0.1 0.00095 19.4 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain PDH PF02153.17 CEG36565.1 - 0.00097 18.2 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase UDPG_MGDP_dh_C PF03720.15 CEG36565.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 CEG36565.1 - 0.0097 16.2 0.3 0.028 14.7 0.1 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEG36565.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEG36565.1 - 0.025 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 CEG36565.1 - 0.045 13.4 0.1 0.087 12.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CEG36565.1 - 0.059 12.9 0.1 0.44 10.1 0.1 2.0 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DpaA_N PF16924.5 CEG36565.1 - 0.075 13.1 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain AFOR_N PF02730.15 CEG36565.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF364 PF04016.12 CEG36565.1 - 0.087 12.4 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative heavy-metal chelation DUF2325 PF10087.9 CEG36565.1 - 0.11 12.6 0.3 21 5.3 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) UDPG_MGDP_dh PF00984.19 CEG36565.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain CBFD_NFYB_HMF PF00808.23 CEG36566.1 - 4.9e-23 81.2 0.1 6.7e-23 80.8 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEG36566.1 - 8e-17 61.8 0.8 8.7e-17 61.7 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CEG36566.1 - 0.0084 16.3 0.4 0.018 15.2 0.1 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 CEG36566.1 - 0.11 12.9 1.5 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Ank_3 PF13606.6 CEG36568.1 - 6.4e-08 32.3 3.2 0.0027 18.1 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 CEG36568.1 - 2.3e-07 31.3 0.2 9.5e-06 26.1 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEG36568.1 - 3.3e-07 30.4 1.1 3e-05 24.2 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CEG36568.1 - 0.00029 21.4 1.3 0.042 14.4 0.2 3.8 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG36568.1 - 0.00057 20.1 0.7 0.0067 16.7 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Nucleoporin_N PF08801.11 CEG36571.1 - 1e-38 133.3 0.0 1.5e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Phage_tail_X PF05489.12 CEG36572.1 - 0.098 12.3 0.3 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Protein X S4 PF01479.25 CEG36574.1 - 0.091 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 S4 domain UPF0020 PF01170.18 CEG36576.1 - 2.8e-20 72.9 0.0 1.3e-18 67.4 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 CEG36576.1 - 7.4e-07 29.4 0.1 1.4e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 THUMP domain Ubie_methyltran PF01209.18 CEG36576.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CEG36576.1 - 0.0044 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain AviRa PF11599.8 CEG36576.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa N6_Mtase PF02384.16 CEG36576.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_25 PF13649.6 CEG36576.1 - 0.078 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Macoilin PF09726.9 CEG36577.1 - 0.57 8.7 10.7 0.64 8.5 10.7 1.1 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 CEG36577.1 - 3.5 7.0 26.5 5 6.4 26.5 1.3 1 0 0 1 1 1 0 SDA1 AIRS_C PF02769.22 CEG36579.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Myb_DNA-binding PF00249.31 CEG36580.1 - 6.6e-10 39.0 0.1 1.9e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ABATE PF07336.11 CEG36580.1 - 0.0061 17.2 0.1 0.0085 16.8 0.1 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator Sulfate_transp PF00916.20 CEG36581.1 - 4.3e-19 68.5 20.8 7.9e-19 67.7 17.2 2.7 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 CEG36581.1 - 1.5e-06 27.9 0.1 3.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEG36581.1 - 7e-06 26.4 24.6 0.00056 20.3 4.1 3.3 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily TIP49 PF06068.13 CEG36582.1 - 0.038 13.2 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 TIP49 P-loop domain HECT PF00632.25 CEG36584.1 - 4e-55 187.5 0.0 7.4e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CEG36584.1 - 3.8e-51 172.2 2.4 2.3e-22 79.4 0.1 3.7 3 0 0 3 3 3 3 SPRY domain MIB_HERC2 PF06701.13 CEG36584.1 - 8.3e-18 64.4 6.3 2.7e-17 62.7 6.3 2.0 1 0 0 1 1 1 1 Mib_herc2 UBA PF00627.31 CEG36584.1 - 1.6e-14 53.5 1.3 5.3e-07 29.4 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UIM PF02809.20 CEG36584.1 - 0.024 14.5 0.5 0.08 12.9 0.5 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif TP53IP5 PF15331.6 CEG36584.1 - 0.2 11.8 1.3 0.59 10.3 1.3 1.7 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RNA_polI_A34 PF08208.11 CEG36587.1 - 8.2e-05 22.8 6.7 0.00035 20.7 0.0 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TMEM51 PF15345.6 CEG36587.1 - 0.054 13.3 0.5 0.069 13.0 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Polyoma_lg_T_C PF06431.11 CEG36587.1 - 5.1 5.9 6.7 6.8 5.4 6.3 1.5 1 1 0 1 1 1 0 Polyomavirus large T antigen C-terminus Adaptin_N PF01602.20 CEG36589.1 - 4.7e-89 299.3 1.1 6e-89 299.0 1.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEG36589.1 - 1.2e-16 61.2 2.4 2.5e-13 50.4 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEG36589.1 - 1.1e-05 25.7 0.1 0.23 11.9 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 CEG36589.1 - 0.0028 17.8 0.3 40 4.4 0.0 4.4 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 CEG36589.1 - 0.037 14.3 0.1 18 5.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat DM4_12 PF07841.13 CEG36589.1 - 0.058 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 DM4/DM12 family Yos1 PF08571.10 CEG36590.1 - 7.7e-21 74.2 1.6 8.7e-21 74.0 1.6 1.0 1 0 0 1 1 1 1 Yos1-like Glu_cyclase_2 PF05096.12 CEG36591.1 - 1.8e-71 240.5 0.3 2.1e-71 240.3 0.3 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase LSM PF01423.22 CEG36592.1 - 8.1e-22 76.7 0.1 9.7e-22 76.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CEG36592.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain COMM_domain PF07258.14 CEG36593.1 - 9.4e-14 51.3 0.3 3.8e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 COMM domain SPO22 PF08631.10 CEG36593.1 - 0.065 12.7 2.0 0.053 13.0 0.5 1.6 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Glu-tRNAGln PF02686.15 CEG36595.1 - 2.1e-07 31.1 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Phosducin PF02114.16 CEG36596.1 - 1.8e-09 36.9 0.4 2.2e-09 36.6 0.4 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CEG36596.1 - 0.027 14.4 0.2 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin DUF4952 PF16310.5 CEG36597.1 - 0.071 13.4 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) FPN1 PF06963.12 CEG36600.1 - 7.6e-92 308.1 23.0 2.5e-91 306.5 23.0 1.8 1 1 0 1 1 1 1 Ferroportin1 (FPN1) OGG_N PF07934.12 CEG36600.1 - 5.5e-24 84.6 0.2 3.5e-23 82.0 0.3 2.2 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CEG36600.1 - 6.2e-12 45.9 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein adh_short_C2 PF13561.6 CEG36601.1 - 9.4e-64 215.2 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG36601.1 - 8.2e-21 74.3 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 CEG36601.1 - 0.0039 16.6 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Trans-2-enoyl-CoA reductase catalytic region EccE PF11203.8 CEG36601.1 - 0.13 12.6 0.1 4.5 7.7 0.0 2.7 2 1 1 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Myotub-related PF06602.14 CEG36602.1 - 7.7e-115 383.6 0.0 1.2e-114 382.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CEG36602.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEG36602.1 - 0.00082 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Prok-RING_2 PF14445.6 CEG36602.1 - 0.0058 16.8 1.0 0.013 15.7 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 2 DSPc PF00782.20 CEG36602.1 - 0.032 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain zf-Sec23_Sec24 PF04810.15 CEG36602.1 - 0.053 13.6 0.3 6.4 6.9 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 CEG36602.1 - 0.16 11.3 6.8 0.086 12.2 4.4 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Lipase_3 PF01764.25 CEG36603.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PRELI PF04707.14 CEG36606.1 - 4.1e-36 124.2 0.0 4.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF2505 PF10698.9 CEG36606.1 - 0.0026 17.9 0.0 0.0041 17.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) HEAT PF02985.22 CEG36607.1 - 4.8e-25 85.5 13.2 0.00074 19.6 0.2 9.8 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 CEG36607.1 - 1.3e-15 57.5 0.0 0.0013 19.0 0.0 6.7 4 2 2 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.7 CEG36607.1 - 8.4e-05 23.1 0.3 0.4 11.3 0.0 4.6 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEG36607.1 - 0.01 15.4 0.0 0.96 9.0 0.0 2.9 2 0 0 2 2 2 0 CLASP N terminal Atypical_Card PF18461.1 CEG36607.1 - 0.051 13.8 0.1 0.58 10.4 0.0 2.6 1 1 1 2 2 2 0 Atypical caspase recruitment domain HEAT_EZ PF13513.6 CEG36607.1 - 0.073 13.6 5.5 7.3 7.2 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat CEP209_CC5 PF16574.5 CEG36609.1 - 0.00044 20.4 7.0 0.00044 20.4 7.0 2.9 2 1 0 3 3 3 1 Coiled-coil region of centrosome protein CE290 DUF4407 PF14362.6 CEG36609.1 - 0.0045 16.4 23.1 0.3 10.4 18.4 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) ATG16 PF08614.11 CEG36609.1 - 0.0064 16.7 26.2 0.0064 16.7 26.2 3.0 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 CEG36609.1 - 0.078 13.0 17.8 0.12 12.4 6.9 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CEG36609.1 - 0.39 10.0 28.5 3.4 7.0 10.9 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3502 PF12010.8 CEG36609.1 - 0.73 10.5 5.9 1.8 9.2 1.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) PRP38_assoc PF12871.7 CEG36609.1 - 0.9 10.2 4.9 0.49 11.0 0.5 2.5 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF641 PF04859.12 CEG36609.1 - 1.2 9.5 18.9 4.7 7.6 7.7 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 CEG36609.1 - 1.8 7.6 23.5 0.26 10.3 17.7 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC92 PF14916.6 CEG36609.1 - 2 8.2 5.9 18 5.2 0.2 3.5 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF730 PF05325.11 CEG36609.1 - 2.5 8.2 6.6 0.62 10.1 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF730) TMPIT PF07851.13 CEG36609.1 - 2.8 7.1 27.6 0.6 9.3 2.7 3.5 2 1 2 4 4 4 0 TMPIT-like protein DUF3037 PF11236.8 CEG36609.1 - 3.2 8.2 6.9 4.4 7.8 2.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) ADIP PF11559.8 CEG36609.1 - 3.3 7.8 30.6 0.36 10.9 7.5 4.1 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 CEG36609.1 - 3.4 8.3 26.7 0.058 14.0 1.9 4.7 4 1 1 5 5 5 0 SlyX Spc7 PF08317.11 CEG36609.1 - 4.5 6.1 32.2 0.6 8.9 24.2 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CEG36609.1 - 7.5 6.0 24.0 1.1 8.8 15.4 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit TolA_bind_tri PF16331.5 CEG36609.1 - 8.8 6.5 18.8 0.34 11.0 1.0 3.7 3 1 0 3 3 3 0 TolA binding protein trimerisation Sec1 PF00995.23 CEG36610.1 - 3.7e-99 333.5 0.1 4.8e-99 333.1 0.1 1.0 1 0 0 1 1 1 1 Sec1 family DNA_primase_lrg PF04104.14 CEG36611.1 - 2.8e-80 269.5 0.4 6.5e-80 268.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit LRR_10 PF18805.1 CEG36612.1 - 0.2 11.3 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat UPF0565 PF10561.9 CEG36613.1 - 3.3e-48 164.4 0.1 7e-24 84.6 0.1 2.2 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 DUF3911 PF13050.6 CEG36617.1 - 0.078 13.1 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) RNase_PH_C PF03725.15 CEG36617.1 - 0.093 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Complex1_LYR PF05347.15 CEG36620.1 - 0.0061 16.6 1.6 0.01 15.8 1.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2371 PF10177.9 CEG36621.1 - 0.08 13.1 0.0 0.087 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Cupin_4 PF08007.12 CEG36622.1 - 3e-63 214.2 0.5 3.6e-63 214.0 0.5 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CEG36622.1 - 1.4e-07 31.6 0.0 2.6e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 CEG36622.1 - 0.0039 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Frag1 PF10277.9 CEG36626.1 - 2.4e-13 50.1 9.4 3.6e-13 49.6 9.2 1.4 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1772 PF08592.11 CEG36626.1 - 0.011 16.1 3.9 0.05 13.9 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF998 PF06197.13 CEG36626.1 - 0.47 10.0 8.1 0.11 12.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) ABC2_membrane PF01061.24 CEG36627.1 - 5.6e-65 218.7 53.6 2e-32 112.3 21.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CEG36627.1 - 1.9e-21 77.0 0.0 2.4e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG36627.1 - 9.6e-06 25.6 0.5 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG36627.1 - 6.7e-05 22.4 0.1 0.23 10.9 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CEG36627.1 - 0.00072 18.8 13.3 0.00072 18.8 13.3 3.0 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 CEG36627.1 - 0.0036 17.0 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CEG36627.1 - 0.013 15.9 0.2 0.043 14.2 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain PPARgamma_N PF12577.8 CEG36627.1 - 0.032 14.9 0.1 0.11 13.2 0.1 1.8 1 0 0 1 1 1 0 PPAR gamma N-terminal region AAA_22 PF13401.6 CEG36627.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rrp44_CSD1 PF17216.3 CEG36627.1 - 0.17 11.6 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain RsgA_GTPase PF03193.16 CEG36627.1 - 0.19 11.6 0.3 0.39 10.6 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase SNARE_assoc PF09335.11 CEG36628.1 - 3.5e-20 72.7 11.4 4.9e-19 69.0 8.9 2.4 2 0 0 2 2 2 2 SNARE associated Golgi protein Bromodomain PF00439.25 CEG36629.1 - 3.7e-18 65.4 0.0 9e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CEG36629.1 - 4.4e-10 39.3 12.3 4.4e-10 39.3 12.3 2.0 2 0 0 2 2 2 1 PHD-finger F5_F8_type_C PF00754.25 CEG36629.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Prok-RING_1 PF14446.6 CEG36629.1 - 0.96 9.4 9.4 0.47 10.4 6.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 CEG36629.1 - 2.4 8.2 9.5 2 8.5 7.0 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid RNase_H2-Ydr279 PF09468.10 CEG36630.1 - 0.016 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DNA_ligase_A_M PF01068.21 CEG36631.1 - 5.9e-55 186.1 0.8 1.8e-54 184.5 0.8 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CEG36631.1 - 1.6e-40 139.3 0.1 3.9e-40 138.0 0.1 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CEG36631.1 - 7.3e-22 77.8 0.1 3.3e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region MHC_II_beta PF00969.19 CEG36631.1 - 0.057 13.5 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Ank_2 PF12796.7 CEG36632.1 - 5.9e-25 87.7 7.3 4.8e-07 30.3 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG36632.1 - 6.3e-21 74.5 8.3 3.1e-06 27.6 0.0 6.4 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG36632.1 - 5.3e-17 61.7 10.6 5.9e-06 26.5 1.6 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG36632.1 - 4.2e-16 57.4 3.6 0.076 13.6 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 CEG36632.1 - 4.1e-12 46.0 20.6 0.0031 17.9 0.4 7.7 8 0 0 8 8 8 3 Ankyrin repeat Glypican PF01153.19 CEG36633.1 - 0.03 13.2 0.0 0.032 13.1 0.0 1.0 1 0 0 1 1 1 0 Glypican Laminin_B PF00052.18 CEG36636.1 - 0.14 12.0 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Laminin B (Domain IV) ATPgrasp_ST PF14397.6 CEG36638.1 - 2.8e-12 46.5 0.4 2.2e-10 40.3 0.1 3.0 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp LRR_6 PF13516.6 CEG36639.1 - 7.1e-08 31.9 4.1 3.9 7.8 0.0 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 CEG36639.1 - 1.1e-07 32.1 1.2 0.75 10.3 0.6 5.9 3 1 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG36639.1 - 0.00084 19.6 4.2 20 6.2 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich Repeat Transp_inhibit PF18791.1 CEG36639.1 - 0.14 11.7 0.8 17 5.0 0.1 4.0 3 1 1 4 4 4 0 Transport inhibitor response 1 protein domain HHH_2 PF12826.7 CEG36640.1 - 0.0017 18.4 0.1 0.0042 17.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ADH_zinc_N_2 PF13602.6 CEG36642.1 - 3.4e-26 92.9 0.0 5.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEG36642.1 - 2.4e-13 50.2 0.2 4.2e-13 49.4 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CEG36642.1 - 0.098 12.9 0.8 0.94 9.7 0.8 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CEG36642.1 - 0.15 11.3 1.9 0.37 10.1 1.9 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RdRP_5 PF07925.11 CEG36644.1 - 0.0057 14.1 0.1 0.007 13.8 0.1 1.0 1 0 0 1 1 1 1 Reovirus RNA-dependent RNA polymerase lambda 3 CBP4 PF07960.11 CEG36644.1 - 0.06 13.2 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 CBP4 DUF2283 PF10049.9 CEG36645.1 - 0.037 14.3 0.0 0.2 11.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2283) SAYSvFN PF10260.9 CEG36647.1 - 1.2e-21 76.4 0.2 1.7e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) PH_RBD PF12068.8 CEG36647.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) Asparaginase_2 PF01112.18 CEG36647.1 - 0.21 10.6 0.5 0.29 10.1 0.5 1.1 1 0 0 1 1 1 0 Asparaginase DUF2207 PF09972.9 CEG36648.1 - 0.075 11.8 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PalH PF08733.10 CEG36648.1 - 0.079 12.0 1.8 0.096 11.7 1.8 1.4 1 1 0 1 1 1 0 PalH/RIM21 DNA_pol_A_exo1 PF01612.20 CEG36649.1 - 8.2e-25 87.5 0.2 1.4e-24 86.7 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease STE2 PF02116.15 CEG36649.1 - 0.047 13.0 0.1 1.8 7.8 0.3 2.1 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR zf-C2H2_4 PF13894.6 CEG36649.1 - 0.054 14.4 8.1 0.13 13.1 1.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 CEG36649.1 - 0.75 9.5 5.4 0.59 9.8 0.3 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 CEG36649.1 - 0.82 10.0 3.9 4.5 7.7 0.0 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Hydrolase PF00702.26 CEG36650.1 - 2.7e-45 155.2 0.2 7.1e-45 153.9 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG36650.1 - 5.5e-44 149.8 0.2 5.5e-44 149.8 0.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 CEG36650.1 - 8.3e-32 109.4 19.6 5.3e-08 33.2 0.2 5.1 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CEG36650.1 - 0.00017 21.4 3.5 0.00063 19.6 0.3 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG36650.1 - 0.015 15.7 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CEG36650.1 - 0.043 13.9 0.4 0.52 10.5 0.0 3.2 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase DUF418 PF04235.12 CEG36650.1 - 0.12 12.4 2.5 0.3 11.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) VHS PF00790.19 CEG36650.1 - 0.24 11.3 2.7 3.3 7.6 0.2 2.5 2 0 0 2 2 2 0 VHS domain Cpn60_TCP1 PF00118.24 CEG36652.1 - 1.4e-166 555.0 0.1 1.6e-166 554.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4968 PF16338.5 CEG36652.1 - 0.064 13.6 0.0 0.63 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Hydrolase PF00702.26 CEG36654.1 - 1e-44 153.3 0.1 2.1e-44 152.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG36654.1 - 3.4e-43 147.3 0.9 5.6e-43 146.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 CEG36654.1 - 1.3e-23 83.2 20.1 5.3e-10 39.6 0.1 5.0 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CEG36654.1 - 2.6e-05 24.1 0.4 7.9e-05 22.5 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CEG36654.1 - 0.048 13.8 0.2 1.1 9.4 0.0 3.3 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase POTRA PF07244.15 CEG36654.1 - 0.059 13.9 0.2 0.21 12.2 0.1 2.0 2 0 0 2 2 2 0 Surface antigen variable number repeat HAD PF12710.7 CEG36654.1 - 0.15 12.4 0.0 0.58 10.5 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase YlaC PF10777.9 CEG36654.1 - 0.16 11.8 0.5 0.46 10.3 0.5 1.8 1 0 0 1 1 1 0 Inner membrane protein YlaC GIDA PF01134.22 CEG36657.1 - 3.9e-150 500.3 0.0 5.6e-150 499.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CEG36657.1 - 1.1e-56 192.4 0.4 1.1e-56 192.4 0.4 1.8 2 0 0 2 2 2 1 GidA associated domain FAD_oxidored PF12831.7 CEG36657.1 - 2.7e-08 33.6 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEG36657.1 - 4.9e-08 32.6 0.1 9.7e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEG36657.1 - 4.2e-07 29.4 6.4 3.9e-05 22.9 2.6 2.7 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 CEG36657.1 - 0.0015 17.9 0.2 0.0036 16.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CEG36657.1 - 0.0025 18.3 0.7 0.0025 18.3 0.7 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG36657.1 - 0.0063 15.8 0.1 0.17 11.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEG36657.1 - 0.0081 15.8 1.3 0.79 9.2 1.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEG36657.1 - 0.028 13.7 1.4 0.079 12.2 0.4 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 CEG36657.1 - 0.092 13.0 2.3 0.91 9.8 1.4 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEG36657.1 - 0.17 10.9 1.4 0.41 9.6 0.8 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CEG36657.1 - 0.52 8.9 8.8 0.085 11.5 1.1 3.2 4 0 0 4 4 4 0 HI0933-like protein Trp_halogenase PF04820.14 CEG36657.1 - 2 7.2 3.5 1.3 7.8 1.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro81C PF17652.1 CEG36659.1 - 9.8e-104 347.3 0.1 1.4e-103 346.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG36659.1 - 1.6e-19 70.2 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DENN PF02141.21 CEG36661.1 - 3e-31 108.8 5.9 2.5e-30 105.8 5.9 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 CEG36661.1 - 4.4e-31 106.4 11.0 0.00023 21.9 0.0 9.1 8 0 0 8 8 8 7 WD domain, G-beta repeat uDENN PF03456.18 CEG36661.1 - 5.9e-14 52.6 0.4 2.4e-13 50.6 0.3 2.2 2 0 0 2 2 2 1 uDENN domain SPA PF08616.10 CEG36661.1 - 0.00065 19.6 0.1 0.002 18.1 0.1 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis C2 PF00168.30 CEG36661.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain PQQ_3 PF13570.6 CEG36661.1 - 0.093 13.2 0.0 36 5.0 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain dDENN PF03455.19 CEG36661.1 - 0.26 11.3 2.3 0.65 10.0 2.3 1.7 1 0 0 1 1 1 0 dDENN domain F-box-like PF12937.7 CEG36663.1 - 1.6e-07 31.1 2.0 1.7e-07 31.0 0.7 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEG36663.1 - 2.1e-07 30.6 3.0 2.1e-07 30.6 3.0 2.1 3 0 0 3 3 3 1 F-box domain Elongin_A PF06881.11 CEG36663.1 - 0.018 15.6 0.1 0.026 15.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DOT1 PF08123.13 CEG36664.1 - 9.5e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Rsa3 PF14615.6 CEG36665.1 - 1.3e-15 56.7 0.6 4.7e-15 54.9 0.2 2.2 2 0 0 2 2 2 1 Ribosome-assembly protein 3 Mog1 PF04603.12 CEG36665.1 - 0.02 15.2 0.9 0.041 14.3 0.5 1.7 1 1 0 1 1 1 0 Ran-interacting Mog1 protein Patatin PF01734.22 CEG36666.1 - 2.3e-27 96.5 0.1 5.2e-27 95.4 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 CEG36666.1 - 3e-20 72.1 0.1 6.4e-12 45.4 0.0 4.1 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain DUF3386 PF11866.8 CEG36666.1 - 0.0075 15.8 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3386) PUB PF09409.10 CEG36666.1 - 0.041 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 PUB domain Pkinase PF00069.25 CEG36667.1 - 2.4e-66 223.8 0.1 3.9e-66 223.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36667.1 - 1.1e-33 116.6 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG36667.1 - 9.7e-07 29.3 0.1 2.9e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CEG36667.1 - 1.2e-06 27.5 1.9 1.4e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEG36667.1 - 3.7e-05 23.2 0.6 9.9e-05 21.8 0.6 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Caleosin PF05042.13 CEG36667.1 - 0.00066 19.7 0.2 0.006 16.5 0.2 2.3 1 1 0 1 1 1 1 Caleosin related protein EF-hand_7 PF13499.6 CEG36667.1 - 0.0014 19.0 0.1 0.018 15.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Kinase-like PF14531.6 CEG36667.1 - 0.0032 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_1 PF00036.32 CEG36667.1 - 0.0041 16.6 0.1 0.021 14.4 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG36667.1 - 0.14 12.2 0.1 0.84 9.7 0.1 2.4 1 0 0 1 1 1 0 EF-hand domain FTA2 PF13095.6 CEG36667.1 - 0.14 11.8 0.4 0.97 9.0 0.1 2.3 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF4366 PF14283.6 CEG36667.1 - 0.17 11.9 0.3 0.39 10.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EF-hand_8 PF13833.6 CEG36667.1 - 0.17 11.8 0.6 2.1 8.2 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain pair LRR_4 PF12799.7 CEG36668.1 - 2.6e-16 59.5 21.1 0.01 16.2 1.2 8.6 5 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG36668.1 - 1.9e-12 46.2 42.4 0.015 15.3 0.0 12.0 15 0 0 15 15 15 5 Leucine Rich repeat WW PF00397.26 CEG36668.1 - 5.9e-08 32.7 5.6 6.3e-05 23.0 2.2 2.4 2 0 0 2 2 2 2 WW domain CEBP_ZZ PF16366.5 CEG36668.1 - 8.9e-05 22.7 3.0 0.00034 20.8 3.0 2.0 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 CEG36668.1 - 0.0066 16.6 5.4 0.017 15.3 5.4 1.7 1 0 0 1 1 1 1 B-box zinc finger IQ PF00612.27 CEG36668.1 - 0.0097 15.6 4.1 0.0097 15.6 4.1 10.5 12 0 0 12 12 12 6 IQ calmodulin-binding motif Opy2 PF09463.10 CEG36668.1 - 0.39 11.1 3.9 1.7 9.1 3.9 2.1 1 0 0 1 1 1 0 Opy2 protein PTR2 PF00854.21 CEG36669.1 - 9e-57 192.7 9.2 4e-56 190.5 8.8 2.0 1 1 0 1 1 1 1 POT family EF_assoc_2 PF08356.12 CEG36670.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 EF hand associated RNA_pol_Rpb2_6 PF00562.28 CEG36672.1 - 0.41 9.6 4.0 0.69 8.9 4.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Chordopox_G3 PF06129.12 CEG36672.1 - 1.2 9.9 3.3 2.8 8.7 0.6 2.8 2 1 0 2 2 2 0 Chordopoxvirus G3 protein MHCassoc_trimer PF08831.10 CEG36672.1 - 5.3 7.1 6.6 20 5.3 0.2 3.4 3 1 1 4 4 4 0 Class II MHC-associated invariant chain trimerisation domain Mtc PF03820.17 CEG36673.1 - 1.8e-99 332.7 0.4 2.1e-99 332.5 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier CbtA PF09490.10 CEG36673.1 - 0.022 14.5 1.1 0.022 14.5 1.1 1.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) ELO PF01151.18 CEG36674.1 - 4.7e-71 239.3 15.0 5.5e-71 239.0 15.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Exog_C PF18026.1 CEG36677.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Y_phosphatase3 PF13350.6 CEG36677.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DnaJ PF00226.31 CEG36678.1 - 2.9e-18 65.7 0.5 5.2e-18 64.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CEG36678.1 - 1.5e-14 53.4 0.2 2.7e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger CZB PF13682.6 CEG36678.1 - 0.095 13.2 0.4 1.2 9.7 0.0 2.3 2 1 0 2 2 2 0 Chemoreceptor zinc-binding domain Aminotran_3 PF00202.21 CEG36679.1 - 0.033 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III RRM_1 PF00076.22 CEG36680.1 - 3.2e-17 62.1 0.0 5.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CEG36680.1 - 5.8e-08 33.2 6.7 5.8e-08 33.2 6.7 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RNase_P_p30 PF01876.16 CEG36684.1 - 1.3e-45 155.5 0.0 2.6e-45 154.5 0.0 1.5 1 1 0 1 1 1 1 RNase P subunit p30 CBFD_NFYB_HMF PF00808.23 CEG36685.1 - 4.1e-06 27.0 0.1 1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEG36685.1 - 0.0032 17.8 0.4 0.0048 17.2 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CEG36685.1 - 0.02 14.9 0.4 0.04 13.9 0.1 1.6 2 0 0 2 2 2 0 Bromodomain associated Gag_p15 PF08723.10 CEG36685.1 - 0.12 12.6 0.1 0.4 10.9 0.1 1.8 1 1 0 1 1 1 0 Gag protein p15 Transp_Tc5_C PF04236.15 CEG36685.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Retrotran_gag_2 PF14223.6 CEG36688.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.7 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type T2SSF PF00482.23 CEG36688.1 - 0.021 14.8 0.2 0.051 13.5 0.2 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Spore-coat_CotZ PF10612.9 CEG36690.1 - 0.05 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Spore coat protein Z TnpV PF14198.6 CEG36690.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Trypsin_2 PF13365.6 CEG36692.1 - 3.2e-14 54.1 0.1 6.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 CEG36692.1 - 0.7 8.5 4.5 0.14 10.8 0.3 1.8 2 0 0 2 2 2 0 Peptidase S46 FYVE PF01363.21 CEG36693.1 - 0.087 13.0 6.6 0.2 11.8 6.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG36693.1 - 0.32 11.2 4.8 0.68 10.2 4.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger NUC173 PF08161.12 CEG36697.1 - 3.8e-55 186.7 5.2 8.9e-55 185.5 0.7 3.3 3 0 0 3 3 3 1 NUC173 domain IFRD PF05004.13 CEG36697.1 - 3.1e-05 23.2 0.6 3.1e-05 23.2 0.6 4.3 5 1 1 6 6 6 2 Interferon-related developmental regulator (IFRD) DUF937 PF06078.11 CEG36697.1 - 1.3 9.7 4.2 22 5.6 0.1 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) HEAT PF02985.22 CEG36697.1 - 1.8 9.0 10.7 39 4.9 0.0 6.9 6 0 0 6 6 6 0 HEAT repeat WD40 PF00400.32 CEG36698.1 - 5.2e-08 33.4 0.2 0.002 18.9 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36698.1 - 0.0002 21.6 0.0 0.37 11.1 0.0 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 CEG36698.1 - 0.052 13.6 0.1 4.9 7.2 0.0 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Kelch_1 PF01344.25 CEG36698.1 - 0.066 12.8 0.4 7.1 6.3 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Ge1_WD40 PF16529.5 CEG36698.1 - 0.19 10.6 0.0 2.5 6.9 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein XAP5 PF04921.14 CEG36699.1 - 1.6e-71 241.0 25.5 1.2e-70 238.3 25.5 2.0 1 1 0 1 1 1 1 XAP5, circadian clock regulator Phostensin PF13914.6 CEG36699.1 - 0.69 10.5 6.1 0.28 11.8 2.6 2.1 1 1 2 3 3 3 0 Phostensin PP1-binding and SH3-binding region UQ_con PF00179.26 CEG36700.1 - 2e-14 53.4 0.0 2.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KIX PF02172.16 CEG36701.1 - 0.019 15.2 5.6 0.15 12.4 1.9 3.2 3 0 0 3 3 3 0 KIX domain PemK_toxin PF02452.17 CEG36701.1 - 0.021 15.2 1.3 0.071 13.5 1.3 1.9 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system FapA PF03961.13 CEG36701.1 - 0.16 10.5 7.7 0.27 9.8 7.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CEG36701.1 - 1.9 6.3 9.2 3.2 5.5 9.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Noelin-1 PF12308.8 CEG36701.1 - 4 7.5 11.9 1.2 9.1 1.2 3.3 3 1 0 3 3 3 0 Neurogenesis glycoprotein CDP-OH_P_transf PF01066.21 CEG36702.1 - 6.3e-14 52.5 0.0 6.3e-14 52.5 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CRAL_TRIO PF00650.20 CEG36704.1 - 4.8e-22 78.4 0.0 8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG36704.1 - 0.027 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Ribosomal_S19e PF01090.19 CEG36704.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e RAP1 PF07218.11 CEG36704.1 - 0.14 10.4 0.3 0.2 9.9 0.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_9 PF00759.19 CEG36704.1 - 0.27 10.6 0.2 0.62 9.4 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 CDP-OH_P_transf PF01066.21 CEG36705.1 - 6.8e-11 42.8 0.1 6.8e-11 42.8 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NAD_binding_2 PF03446.15 CEG36706.1 - 6.1e-45 153.2 1.9 1.8e-44 151.7 0.8 2.3 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEG36706.1 - 8.7e-35 119.6 0.2 1.6e-34 118.7 0.2 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CEG36706.1 - 2.9e-09 37.4 0.0 8.5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CEG36706.1 - 2e-06 27.3 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEG36706.1 - 1.5e-05 25.1 0.0 6.5e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CEG36706.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEG36706.1 - 0.032 14.7 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF5575 PF17738.1 CEG36706.1 - 0.04 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) ApbA PF02558.16 CEG36706.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sad1_UNC PF07738.13 CEG36707.1 - 5.8e-31 107.2 0.0 1.1e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RVP_2 PF08284.11 CEG36708.1 - 0.12 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Methyltransf_23 PF13489.6 CEG36708.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HMGL-like PF00682.19 CEG36712.1 - 9.2e-93 310.6 0.0 1.4e-92 310.0 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CEG36712.1 - 6.3e-34 116.7 2.6 1.4e-33 115.6 2.6 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain SH3_14 PF18343.1 CEG36712.1 - 0.078 13.1 0.5 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Dda helicase SH3 domain NAP PF00956.18 CEG36713.1 - 1.6e-73 247.2 0.8 2.3e-73 246.7 0.8 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DMAP_binding PF06464.11 CEG36713.1 - 0.26 12.1 3.4 0.18 12.6 0.6 2.1 2 0 0 2 2 2 0 DMAP1-binding Domain Sigma70_ner PF04546.13 CEG36713.1 - 7.4 6.4 15.9 3.1 7.6 1.7 2.6 2 1 1 3 3 3 0 Sigma-70, non-essential region PBP1_TM PF14812.6 CEG36713.1 - 8.4 6.8 6.9 30 5.1 6.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYVE PF01363.21 CEG36716.1 - 2.2e-12 46.9 9.6 4.8e-12 45.8 9.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 CEG36716.1 - 0.45 10.7 4.5 1.4 9.2 4.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF326 PF03860.16 CEG36716.1 - 1.9 8.6 5.9 4 7.5 5.9 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) Pkinase PF00069.25 CEG36718.1 - 2e-11 43.8 0.1 3.9e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 CEG36718.1 - 0.0017 17.2 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG36718.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family rve PF00665.26 CEG36721.1 - 1.1e-15 57.8 0.0 2.4e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEG36721.1 - 5.1e-07 29.5 1.1 8.2e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CEG36721.1 - 0.00028 20.6 0.0 0.00077 19.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Tub PF01167.18 CEG36723.1 - 1.2e-71 241.3 0.0 1.6e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 CEG36723.1 - 7.7e-09 35.8 4.1 7.7e-09 35.8 4.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG36723.1 - 5.4e-05 23.4 3.7 0.00016 21.9 3.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 CEG36723.1 - 0.00012 22.2 3.8 0.00023 21.2 3.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 CEG36723.1 - 0.00042 20.1 4.0 0.0014 18.4 4.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3527 PF12043.8 CEG36723.1 - 0.0014 18.3 0.1 0.0035 17.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) zf-C3HC4_3 PF13920.6 CEG36723.1 - 0.026 14.4 5.4 0.057 13.3 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG36723.1 - 0.049 13.7 2.3 0.091 12.8 1.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CEG36723.1 - 0.055 13.4 2.8 0.13 12.3 2.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 CEG36723.1 - 0.59 9.9 4.6 0.31 10.8 0.8 2.5 2 1 0 2 2 2 0 RING-like zinc finger LicD PF04991.13 CEG36724.1 - 0.16 12.1 0.0 1.3 9.1 0.0 1.9 1 1 1 2 2 2 0 LicD family Pep_deformylase PF01327.21 CEG36725.1 - 6.9e-31 107.0 0.0 7.3e-23 80.9 0.0 2.0 1 1 1 2 2 2 2 Polypeptide deformylase PAXIP1_C PF15364.6 CEG36726.1 - 0.023 15.0 3.5 0.023 15.0 3.5 2.2 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Nse4_C PF08743.10 CEG36726.1 - 0.16 12.3 2.1 10 6.5 0.2 2.7 2 1 0 2 2 2 0 Nse4 C-terminal PHC2_SAM_assoc PF16616.5 CEG36726.1 - 0.28 12.0 14.8 0.19 12.6 13.0 1.7 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Histone_HNS PF00816.21 CEG36726.1 - 5.9 7.8 9.8 28 5.6 9.5 2.3 1 1 1 2 2 2 0 H-NS histone family Pkinase PF00069.25 CEG36727.1 - 6.2e-71 238.8 0.1 8.6e-71 238.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36727.1 - 1.9e-37 129.0 0.0 2.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CEG36727.1 - 4.3e-14 50.9 0.3 1.3e-05 24.4 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CEG36727.1 - 1.9e-13 50.6 0.9 0.00055 20.3 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG36727.1 - 5e-12 44.7 2.2 0.32 11.0 0.0 5.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CEG36727.1 - 4.8e-11 42.3 0.2 0.00026 20.8 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair APH PF01636.23 CEG36727.1 - 0.0002 21.4 0.4 0.07 13.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family EF-hand_5 PF13202.6 CEG36727.1 - 0.002 17.5 0.0 0.18 11.3 0.0 3.1 3 0 0 3 3 3 1 EF hand Kdo PF06293.14 CEG36727.1 - 0.0034 16.8 0.3 0.0057 16.0 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG36727.1 - 0.024 13.6 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Complex1_LYR PF05347.15 CEG36728.1 - 1.6e-15 56.8 2.4 1.6e-15 56.8 2.4 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEG36728.1 - 1.9e-07 31.7 2.0 2.2e-07 31.5 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CEG36728.1 - 0.00018 22.1 0.2 0.00021 21.9 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like SPATA24 PF15175.6 CEG36728.1 - 0.0056 16.6 0.0 0.0056 16.6 0.0 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 RVT_2 PF07727.14 CEG36732.1 - 1.5e-08 34.6 0.0 1.7e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_ParB PF17762.1 CEG36733.1 - 0.0089 15.8 0.6 0.033 14.0 0.2 2.0 1 1 0 2 2 2 1 HTH domain found in ParB protein NDUF_B5 PF09781.9 CEG36733.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Phage_tail_3 PF08813.11 CEG36733.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein, TTP Propep_M14 PF02244.16 CEG36733.1 - 0.12 12.8 0.4 15 6.1 0.0 2.4 2 1 0 2 2 2 0 Carboxypeptidase activation peptide CD45 PF12567.8 CEG36733.1 - 0.19 11.7 0.7 3.5 7.7 0.1 2.5 2 1 1 3 3 3 0 Leukocyte receptor CD45 Ribosomal_S10 PF00338.22 CEG36736.1 - 2.5e-29 101.4 0.1 3.3e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Peptidase_C26 PF07722.13 CEG36738.1 - 1e-19 71.2 0.0 3.6e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 CEG36738.1 - 1.2e-10 41.4 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 CEG36738.1 - 0.028 14.2 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 SNO glutamine amidotransferase family Exo_endo_phos PF03372.23 CEG36739.1 - 3.5e-19 69.3 0.0 1.1e-18 67.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEG36739.1 - 0.085 12.7 0.4 1.7 8.5 0.0 2.9 3 1 0 3 3 3 0 Endonuclease-reverse transcriptase His_Phos_2 PF00328.22 CEG36739.1 - 0.16 11.3 1.7 0.33 10.3 0.2 1.9 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.23 CEG36740.1 - 3.6e-08 33.2 0.0 6.3e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FYVE PF01363.21 CEG36741.1 - 5.8e-12 45.6 15.8 8.2e-12 45.1 13.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 CEG36741.1 - 2e-05 25.3 0.0 7.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 CEG36741.1 - 0.00079 19.6 5.2 0.0021 18.3 5.2 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 CEG36741.1 - 10 6.6 9.8 3.4 8.1 6.4 1.9 2 0 0 2 2 2 0 C1 domain Bromodomain PF00439.25 CEG36742.1 - 1.5e-35 121.1 0.6 4.7e-18 65.0 0.2 2.7 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 CEG36742.1 - 1e-31 108.5 15.5 6.3e-08 33.2 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-HC5HC2H PF13771.6 CEG36742.1 - 1e-08 35.3 4.6 1e-08 35.3 4.6 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG36742.1 - 4.2e-06 26.9 4.5 1.3e-05 25.3 4.5 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain CRCB PF02537.15 CEG36743.1 - 7.6e-09 35.8 16.4 2.6e-06 27.6 2.7 2.9 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) PsbL PF02419.17 CEG36743.1 - 0.57 10.2 2.9 8.5 6.5 0.5 2.7 2 0 0 2 2 2 0 PsbL protein WD40 PF00400.32 CEG36745.1 - 5.9e-13 49.1 3.8 0.0016 19.2 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36745.1 - 4.7e-05 23.6 0.0 0.56 10.5 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CEG36745.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller RRM_1 PF00076.22 CEG36746.1 - 5.4e-20 71.0 0.0 1.5e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG36746.1 - 0.00016 21.7 0.6 0.00055 20.0 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CEG36746.1 - 0.0004 20.0 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.12 CEG36746.1 - 0.022 15.1 6.1 0.027 14.7 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4175 PF13779.6 CEG36746.1 - 0.027 12.4 9.2 0.032 12.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) T-box_assoc PF16176.5 CEG36746.1 - 0.068 13.3 0.4 0.098 12.7 0.4 1.2 1 0 0 1 1 1 0 T-box transcription factor-associated LMBR1 PF04791.16 CEG36746.1 - 0.11 11.4 0.5 0.11 11.4 0.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Androgen_recep PF02166.16 CEG36746.1 - 0.18 10.6 0.4 0.24 10.2 0.4 1.1 1 0 0 1 1 1 0 Androgen receptor LicD PF04991.13 CEG36746.1 - 0.45 10.6 5.2 0.65 10.1 5.2 1.2 1 0 0 1 1 1 0 LicD family SOAR PF16533.5 CEG36746.1 - 0.51 10.3 11.4 1.1 9.3 11.4 1.5 1 0 0 1 1 1 0 STIM1 Orai1-activating region RRN3 PF05327.11 CEG36746.1 - 1.1 7.7 8.7 1.5 7.3 8.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sec62 PF03839.16 CEG36746.1 - 1.5 8.2 9.5 2.3 7.7 9.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 PIEZO PF15917.5 CEG36746.1 - 1.7 8.1 13.2 2.9 7.3 13.2 1.4 1 0 0 1 1 1 0 Piezo DUF2228 PF10228.9 CEG36746.1 - 1.7 8.3 9.6 2.6 7.7 9.6 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) OrfB_IS605 PF01385.19 CEG36746.1 - 5.5 7.2 10.6 1.2 9.4 7.0 1.8 2 0 0 2 2 2 0 Probable transposase ALMT PF11744.8 CEG36746.1 - 6 5.6 6.7 7.9 5.2 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter 5_nucleotid_C PF02872.18 CEG36747.1 - 8.5e-21 74.8 0.0 2.1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CEG36747.1 - 3.6e-07 30.9 0.0 6.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.28 CEG36748.1 - 1.2e-13 51.8 0.0 3.8e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEG36748.1 - 8e-10 38.7 14.4 8e-10 38.7 14.4 2.3 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 CEG36748.1 - 1.3e-06 28.6 0.1 5.3e-06 26.6 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG36748.1 - 0.0003 20.6 0.0 0.0014 18.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 CEG36748.1 - 0.025 14.6 0.1 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DUF5344 PF17279.2 CEG36748.1 - 0.046 14.3 0.8 0.1 13.2 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5344) FlgN PF05130.12 CEG36748.1 - 0.083 13.4 0.8 0.083 13.4 0.8 1.8 2 0 0 2 2 2 0 FlgN protein HAT_KAT11 PF08214.11 CEG36749.1 - 3.5e-26 92.3 0.3 3.5e-26 92.3 0.3 3.5 2 1 0 2 2 2 1 Histone acetylation protein zf-TAZ PF02135.16 CEG36749.1 - 3.7e-23 81.8 63.3 5.1e-11 42.9 15.5 5.4 6 0 0 6 6 6 3 TAZ zinc finger Bromodomain PF00439.25 CEG36749.1 - 2.1e-19 69.4 0.1 1.6e-18 66.5 0.1 2.6 2 0 0 2 2 2 1 Bromodomain ZZ PF00569.17 CEG36749.1 - 8.7e-08 31.9 6.1 8.7e-08 31.9 6.1 4.9 7 0 0 7 7 7 1 Zinc finger, ZZ type PHD PF00628.29 CEG36749.1 - 1.1e-05 25.3 3.4 1.1e-05 25.3 3.4 5.1 5 0 0 5 5 5 1 PHD-finger DUF902 PF06001.13 CEG36749.1 - 0.0043 17.5 3.6 0.014 15.9 3.6 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) FUSC PF04632.12 CEG36749.1 - 4.2 5.8 15.7 11 4.4 15.7 1.7 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glucan_synthase PF02364.15 CEG36750.1 - 4.1e-165 551.2 10.4 5.1e-149 498.0 5.0 2.9 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEG36750.1 - 2.2e-26 92.7 0.2 1.5e-25 90.0 0.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 CEG36750.1 - 8.9e-21 74.3 25.3 8.9e-21 74.3 25.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG36750.1 - 3.9e-10 39.2 24.9 3.9e-10 39.2 24.9 5.3 3 2 4 7 7 7 1 Major Facilitator Superfamily Ribosomal_L18A PF01775.17 CEG36752.1 - 3.3e-43 146.6 0.7 4.4e-43 146.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A TPR_1 PF00515.28 CEG36753.1 - 1.8e-26 90.8 18.5 0.00039 20.1 0.1 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 CEG36753.1 - 4.9e-24 85.0 0.0 3e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 CEG36753.1 - 6.2e-22 75.9 23.3 0.0097 16.0 0.0 8.3 8 0 0 8 8 7 7 Tetratricopeptide repeat Pkinase PF00069.25 CEG36753.1 - 2.3e-19 69.8 0.0 3.5e-18 65.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain TPR_8 PF13181.6 CEG36753.1 - 3.2e-19 67.5 16.5 0.00026 21.0 0.0 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36753.1 - 3.5e-15 55.4 13.1 0.00033 20.3 0.1 6.2 5 1 1 6 6 6 4 TPR repeat TPR_14 PF13428.6 CEG36753.1 - 2.5e-14 52.7 7.0 0.15 12.9 0.0 7.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36753.1 - 1.4e-11 44.8 5.8 0.058 13.9 0.0 6.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36753.1 - 6.7e-10 38.7 2.3 0.0065 16.8 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36753.1 - 5.8e-08 32.8 5.3 0.043 13.9 1.3 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36753.1 - 6.4e-08 32.8 12.8 0.24 11.7 1.5 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 CEG36753.1 - 8.5e-07 29.2 4.5 0.054 13.8 0.1 5.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG36753.1 - 2.4e-05 24.0 15.0 4.7 7.5 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG36753.1 - 0.0037 17.9 15.5 2.5 8.8 0.0 6.3 3 3 3 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 CEG36753.1 - 0.0098 16.4 0.7 0.67 10.7 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CEG36753.1 - 0.01 15.9 4.2 16 5.7 0.1 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 CEG36753.1 - 0.011 16.1 2.4 23 5.4 0.1 4.7 2 2 2 4 4 4 0 Bacterial transcriptional activator domain APH PF01636.23 CEG36753.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family ANAPC3 PF12895.7 CEG36753.1 - 0.086 13.1 12.7 8.3 6.7 1.4 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG36753.1 - 0.15 12.8 11.1 19 6.2 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEG36753.1 - 0.91 9.2 4.6 16 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEG36753.1 - 2.7 8.0 12.1 9.2 6.3 0.1 5.4 5 1 1 6 6 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 CEG36755.1 - 1.4e-14 54.0 0.5 1.8e-06 28.0 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HEAT_EZ PF13513.6 CEG36756.1 - 2e-20 72.9 15.1 3.7e-10 40.1 0.0 10.7 8 4 5 13 13 13 3 HEAT-like repeat HEAT PF02985.22 CEG36756.1 - 2.7e-15 55.1 17.3 0.067 13.5 0.0 11.7 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 CEG36756.1 - 9.6e-13 48.3 1.6 0.98 9.9 0.0 8.0 5 2 2 7 7 7 4 HEAT repeats IBN_N PF03810.19 CEG36756.1 - 2e-10 40.4 0.8 6.6e-10 38.8 0.4 2.2 2 0 0 2 2 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CEG36756.1 - 1.7e-09 38.1 0.0 0.085 13.5 0.0 5.2 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEG36756.1 - 4e-07 30.2 0.1 0.23 11.5 0.0 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 CEG36756.1 - 0.00024 21.0 0.0 0.93 9.4 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) UME PF08064.13 CEG36756.1 - 0.0012 18.7 0.0 0.94 9.4 0.1 3.6 4 0 0 4 4 4 1 UME (NUC010) domain RRN3 PF05327.11 CEG36756.1 - 0.017 13.7 0.5 0.031 12.8 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CLASP_N PF12348.8 CEG36756.1 - 0.042 13.4 0.0 83 2.6 0.0 3.9 3 2 1 4 4 4 0 CLASP N terminal MMS19_C PF12460.8 CEG36756.1 - 0.076 12.1 13.3 1.8 7.6 0.0 4.9 6 1 1 7 7 6 0 RNAPII transcription regulator C-terminal Tti2 PF10521.9 CEG36756.1 - 0.09 12.3 0.7 17 4.9 0.0 3.8 3 1 1 4 4 4 0 Tti2 family RTP1_C1 PF10363.9 CEG36756.1 - 0.18 12.0 0.7 7.8 6.7 0.0 3.7 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 CEG36756.1 - 0.18 10.9 4.1 7.1 5.6 0.2 3.4 2 1 1 3 3 3 0 Dopey, N-terminal Arm PF00514.23 CEG36756.1 - 0.25 11.4 11.2 27 5.0 0.0 6.8 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat Cwf_Cwc_15 PF04889.12 CEG36756.1 - 0.72 9.5 9.8 1.2 8.9 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CEG36756.1 - 5.3 5.0 5.4 6 4.8 4.4 1.5 2 0 0 2 2 2 0 DNA polymerase phi ParA PF10609.9 CEG36757.1 - 9.7e-94 313.4 0.3 3.7e-83 278.8 0.6 2.0 1 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CEG36757.1 - 3e-14 53.2 0.0 1.6e-12 47.6 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEG36757.1 - 1.6e-08 34.7 0.4 3.1e-07 30.5 0.4 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CEG36757.1 - 9.7e-08 31.6 0.0 4.3e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CEG36757.1 - 2.6e-07 30.2 3.3 2e-06 27.2 0.4 2.6 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 CEG36757.1 - 5e-05 23.0 0.1 9.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CEG36757.1 - 0.00093 19.1 0.3 0.026 14.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_26 PF13500.6 CEG36757.1 - 0.0012 18.8 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 CEG36757.1 - 0.0016 18.0 0.1 0.012 15.1 0.1 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 CEG36757.1 - 0.0017 17.4 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CEG36757.1 - 0.0022 17.9 0.1 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Fer4_NifH PF00142.18 CEG36757.1 - 0.0024 17.3 0.1 0.024 14.1 0.0 2.3 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 CEG36757.1 - 0.01 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 CEG36757.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CEG36757.1 - 0.011 15.6 0.4 0.021 14.8 0.4 1.4 1 0 0 1 1 1 0 NACHT domain CLP1_P PF16575.5 CEG36757.1 - 0.029 14.2 0.2 0.1 12.4 0.2 2.1 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DAP3 PF10236.9 CEG36757.1 - 0.037 13.2 0.1 0.072 12.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CEG36757.1 - 0.04 14.3 0.1 0.073 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 CEG36757.1 - 0.061 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 CEG36757.1 - 0.083 12.5 0.2 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirC1 PF07015.11 CEG36757.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Rad17 PF03215.15 CEG36757.1 - 0.12 12.3 0.2 0.32 10.9 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain PP2C PF00481.21 CEG36758.1 - 1.3e-53 182.3 0.0 7.2e-52 176.6 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 CEG36758.1 - 8.1e-17 61.7 1.6 2.1e-16 60.3 1.6 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG36758.1 - 5.8e-07 29.9 3.4 4.3e-06 27.1 3.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PP2C_2 PF13672.6 CEG36758.1 - 3.9e-05 23.4 0.0 9.6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Methyltransf_PK PF05891.12 CEG36760.1 - 9.2e-64 214.9 0.0 5.1e-58 196.2 0.0 2.1 1 1 1 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CEG36760.1 - 1.4e-08 35.3 0.0 2.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG36760.1 - 4.8e-08 33.5 0.0 8.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG36760.1 - 2.6e-07 31.3 0.0 4.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG36760.1 - 2.6e-05 24.1 0.0 7.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CEG36760.1 - 3.7e-05 23.1 0.0 6.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Bin3 PF06859.12 CEG36760.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) HA2 PF04408.23 CEG36761.1 - 6.4e-20 71.4 0.1 2e-19 69.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG36761.1 - 1.5e-15 57.3 0.0 3.5e-13 49.7 0.0 2.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG36761.1 - 2.6e-14 53.5 0.1 9.5e-14 51.7 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG36761.1 - 9.2e-06 25.5 0.1 2.9e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG36761.1 - 0.0012 19.2 0.5 0.0052 17.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEG36761.1 - 0.0046 16.1 0.3 0.011 14.8 0.3 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 CEG36761.1 - 0.013 14.9 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CEG36761.1 - 0.024 15.1 1.1 1.3 9.5 0.1 3.5 3 1 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 CEG36761.1 - 0.042 13.6 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKA1 PF07160.12 CEG36762.1 - 0.0016 18.4 2.7 0.0016 18.4 2.7 2.1 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Syntaxin_2 PF14523.6 CEG36762.1 - 0.0017 18.7 9.7 0.31 11.4 0.6 2.6 2 1 0 2 2 2 2 Syntaxin-like protein MCPsignal PF00015.21 CEG36762.1 - 0.0032 17.3 5.5 0.0032 17.3 5.5 2.4 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_connect_1 PF05135.13 CEG36762.1 - 0.011 16.2 0.6 0.04 14.4 0.1 2.1 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein Syntaxin PF00804.25 CEG36762.1 - 0.015 14.9 3.0 0.015 14.9 3.0 2.8 2 1 1 3 3 3 0 Syntaxin SNARE PF05739.19 CEG36762.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.3 2 0 0 2 2 2 0 SNARE domain DUF1664 PF07889.12 CEG36762.1 - 0.033 14.2 13.0 0.17 12.0 2.2 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Trimer_CC PF08954.11 CEG36762.1 - 0.048 13.2 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 0 Trimerisation motif SRPRB PF09439.10 CEG36762.1 - 0.11 12.0 2.9 0.072 12.5 0.8 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FlaC_arch PF05377.11 CEG36762.1 - 0.13 12.7 0.6 0.13 12.7 0.6 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RPN2_C PF18004.1 CEG36762.1 - 0.19 11.7 4.2 0.28 11.1 4.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Fib_alpha PF08702.10 CEG36762.1 - 0.29 11.3 10.2 9 6.5 8.9 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CEG36762.1 - 0.44 10.8 9.6 1.5 9.1 1.2 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Phage_GPL PF05926.11 CEG36762.1 - 0.51 10.3 8.2 4.3 7.3 0.1 2.9 2 1 1 3 3 3 0 Phage head completion protein (GPL) DUF3734 PF12536.8 CEG36762.1 - 0.61 10.5 6.4 0.21 12.0 0.8 2.6 2 1 0 3 3 3 0 Patatin phospholipase Syntaxin-6_N PF09177.11 CEG36762.1 - 0.8 10.3 9.3 4 8.0 0.1 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 CEG36762.1 - 1.1 9.3 9.9 0.5 10.4 2.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 CEG36762.1 - 1.2 9.0 2.9 2.1 8.2 0.6 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 RasGAP_C PF03836.15 CEG36762.1 - 1.6 8.9 8.6 0.42 10.8 3.9 2.1 1 1 1 2 2 2 0 RasGAP C-terminus Spc7 PF08317.11 CEG36762.1 - 1.8 7.4 16.3 0.66 8.8 13.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 CEG36762.1 - 5.2 7.1 16.6 1.8 8.6 11.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V-SNARE PF05008.15 CEG36762.1 - 5.2 7.5 11.5 1.3 9.4 2.5 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus ABC_tran_CTD PF16326.5 CEG36762.1 - 8.1 6.8 12.0 1.1 9.6 3.8 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Presenilin PF01080.17 CEG36764.1 - 1.8e-103 346.4 0.3 1.8e-103 346.4 0.3 2.2 2 1 0 2 2 2 1 Presenilin LCE PF14672.6 CEG36764.1 - 0.17 12.5 0.9 0.47 11.1 0.9 1.7 1 0 0 1 1 1 0 Late cornified envelope Orthopox_F8 PF05886.11 CEG36764.1 - 0.64 10.2 3.7 0.31 11.2 1.0 1.8 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Oxidored_q2 PF00420.24 CEG36764.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2052 PF09747.9 CEG36765.1 - 3e-32 112.4 16.1 8.6e-17 61.9 7.6 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) GlutR_N PF05201.15 CEG36765.1 - 0.069 12.9 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain DUF2779 PF11074.8 CEG36765.1 - 0.086 13.3 1.0 0.15 12.6 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) BBE PF08031.12 CEG36765.1 - 0.3 11.2 2.4 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Berberine and berberine like Acyl-CoA_dh_C PF12806.7 CEG36767.1 - 0.058 13.5 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Ribosomal_S30 PF04758.14 CEG36770.1 - 7.5e-29 99.7 5.0 9e-29 99.4 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 MTHFR PF02219.17 CEG36770.1 - 0.061 12.6 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase DivIC PF04977.15 CEG36771.1 - 0.043 13.6 0.6 0.043 13.6 0.6 5.2 4 2 1 5 5 5 0 Septum formation initiator FYVE PF01363.21 CEG36772.1 - 4.6e-14 52.3 10.4 9e-14 51.4 10.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger YABBY PF04690.13 CEG36772.1 - 0.14 12.7 3.4 0.1 13.1 0.9 2.0 2 0 0 2 2 2 0 YABBY protein FYVE_2 PF02318.16 CEG36772.1 - 0.16 12.2 8.4 0.34 11.1 8.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Mito_carr PF00153.27 CEG36777.1 - 7e-53 176.5 5.2 1e-18 67.0 0.2 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein RhoGEF67_u1 PF16615.5 CEG36777.1 - 0.083 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 zf-RING_2 PF13639.6 CEG36779.1 - 2e-10 40.8 11.7 4.1e-10 39.8 11.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG36779.1 - 9.5e-10 38.2 6.5 1.9e-09 37.2 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG36779.1 - 1.1e-08 34.7 10.1 2.1e-08 33.9 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG36779.1 - 4.5e-08 33.0 6.9 8.4e-08 32.1 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG36779.1 - 5.7e-08 32.6 8.7 1.2e-07 31.6 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEG36779.1 - 1.8e-07 30.9 6.7 3.8e-07 29.8 6.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG36779.1 - 2.6e-07 30.4 10.5 5e-07 29.5 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG36779.1 - 1.4e-05 25.3 6.7 3.4e-05 24.0 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CEG36779.1 - 4e-05 23.7 10.3 7.7e-05 22.8 10.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CEG36779.1 - 0.00021 21.1 5.2 0.00044 20.1 5.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 CEG36779.1 - 0.016 15.3 2.3 0.033 14.2 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CEG36779.1 - 0.02 14.5 6.2 0.046 13.4 6.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF5533 PF17685.1 CEG36779.1 - 0.022 15.2 0.5 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5533) zf-RING_11 PF17123.5 CEG36779.1 - 0.068 12.9 5.6 0.15 11.8 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CEG36779.1 - 0.12 12.2 4.6 0.24 11.3 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CEG36779.1 - 0.39 10.9 4.3 0.97 9.6 4.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 CEG36779.1 - 1.6 8.8 5.0 3.4 7.7 5.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 CEG36779.1 - 6.7 6.6 7.8 39 4.1 7.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RXLR PF16810.5 CEG36780.1 - 0.00046 20.6 0.1 0.00053 20.4 0.1 1.2 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Myosin_head PF00063.21 CEG36782.1 - 2.9e-228 759.5 0.3 4.6e-228 758.8 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) WW PF00397.26 CEG36782.1 - 3.4e-09 36.6 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 WW domain IQ PF00612.27 CEG36782.1 - 1e-05 24.9 22.3 0.037 13.8 0.3 5.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif APG6_N PF17675.1 CEG36782.1 - 0.0037 17.8 4.4 0.0037 17.8 4.4 2.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Myosin_N PF02736.19 CEG36782.1 - 0.0041 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ZapB PF06005.12 CEG36782.1 - 0.0084 16.5 16.3 0.059 13.8 0.3 4.3 4 0 0 4 4 4 2 Cell division protein ZapB AAA_16 PF13191.6 CEG36782.1 - 0.011 16.1 0.0 0.06 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEG36782.1 - 0.03 14.6 0.0 0.15 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 CEG36782.1 - 0.041 14.0 7.7 0.87 9.7 2.7 3.1 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 CEG36782.1 - 0.072 12.9 19.8 0.057 13.2 2.7 3.7 2 1 1 3 3 3 0 Septum formation initiator Torsin PF06309.11 CEG36782.1 - 0.098 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Torsin SlyX PF04102.12 CEG36782.1 - 0.11 13.2 0.1 0.11 13.2 0.1 4.3 4 1 1 5 5 4 0 SlyX AAA_18 PF13238.6 CEG36782.1 - 0.16 12.5 1.9 0.4 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CEG36782.1 - 0.16 12.5 2.8 0.19 12.2 0.1 2.5 2 0 0 2 2 2 0 ABC transporter FlaC_arch PF05377.11 CEG36782.1 - 0.55 10.7 4.1 23 5.4 0.7 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 CEG36782.1 - 0.64 10.1 11.8 1.9 8.6 11.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 CEG36782.1 - 0.98 10.4 14.4 0.16 12.9 6.7 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 CEG36782.1 - 1 9.2 16.6 0.35 10.7 9.9 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CEG36782.1 - 1.4 9.0 17.9 0.069 13.2 8.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CEG36782.1 - 4 6.7 10.0 9.4 5.5 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 CEG36782.1 - 5.4 7.1 20.4 0.43 10.6 2.9 3.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 CEG36782.1 - 6 6.9 18.0 15 5.7 8.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3847 PF12958.7 CEG36782.1 - 6.3 7.0 7.9 7 6.9 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) MCD PF05292.11 CEG36783.1 - 4.2e-94 314.9 0.0 6.8e-94 314.2 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 CEG36783.1 - 2.1e-12 47.0 0.2 6.8e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain EF-hand_1 PF00036.32 CEG36783.1 - 3.1e-12 45.1 4.3 1.6e-06 27.3 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEG36783.1 - 2.1e-09 37.1 3.6 7e-05 22.6 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CEG36783.1 - 3.7e-09 36.9 0.1 0.001 19.5 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG36783.1 - 1e-07 31.1 2.1 0.00029 20.2 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG36783.1 - 6.9e-07 28.7 1.7 0.0064 16.3 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain DUF962 PF06127.11 CEG36785.1 - 5.5e-26 90.5 0.6 1e-25 89.6 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Pkinase PF00069.25 CEG36786.1 - 1.4e-43 149.2 0.0 2.3e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36786.1 - 9e-39 133.3 0.0 1.7e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG36786.1 - 3.1e-07 30.1 10.4 8.5e-05 22.2 2.3 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEG36786.1 - 6e-06 26.5 12.6 0.0016 18.8 0.2 4.4 1 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG36786.1 - 0.0064 16.9 1.8 16 6.5 0.0 5.0 5 1 0 5 5 5 1 Leucine Rich Repeat Haspin_kinase PF12330.8 CEG36786.1 - 0.013 14.4 0.1 0.043 12.8 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Syndecan PF01034.20 CEG36786.1 - 0.082 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Kdo PF06293.14 CEG36786.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 CEG36786.1 - 7.8 6.8 11.5 26 5.2 0.5 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Aa_trans PF01490.18 CEG36788.1 - 6.1e-06 25.2 0.8 2.4e-05 23.2 0.6 1.8 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein Sel1 PF08238.12 CEG36789.1 - 1.2e-38 130.6 10.8 1.7e-08 34.9 0.1 5.9 6 0 0 6 6 6 5 Sel1 repeat mRNA_cap_enzyme PF01331.19 CEG36790.1 - 1.4e-37 129.4 0.3 6.7e-37 127.2 0.2 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CEG36790.1 - 8.4e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DSPc PF00782.20 CEG36790.1 - 9.2e-05 22.3 0.0 0.00033 20.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain TPR_1 PF00515.28 CEG36792.1 - 2e-29 100.2 49.5 2e-06 27.4 1.0 16.4 15 2 3 18 18 18 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36792.1 - 4.4e-27 92.0 50.1 0.0011 18.9 1.1 15.3 16 2 2 18 18 15 8 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36792.1 - 2.1e-12 47.2 48.8 0.016 15.5 0.9 11.1 4 4 8 12 12 11 5 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36792.1 - 4.7e-12 45.9 31.7 0.37 11.0 0.0 9.9 7 2 1 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36792.1 - 6.2e-11 41.8 21.6 0.0062 16.2 0.0 9.4 9 1 2 11 11 10 4 TPR repeat TPR_6 PF13174.6 CEG36792.1 - 4.5e-10 39.5 19.6 0.00059 20.3 0.0 10.1 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG36792.1 - 3.8e-09 37.0 33.1 0.00088 19.9 0.3 7.0 7 1 2 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36792.1 - 7.1e-09 35.5 20.9 2.5 8.7 0.0 10.1 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36792.1 - 1.5e-07 31.1 25.9 1.4 9.3 0.5 11.0 12 1 0 13 13 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36792.1 - 2.1e-07 31.3 13.6 0.0082 16.6 0.1 6.6 7 1 1 8 8 6 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEG36792.1 - 5.5e-06 26.4 4.3 0.0036 17.3 0.1 3.3 3 1 0 3 3 3 2 Putative TPR-like repeat ANAPC3 PF12895.7 CEG36792.1 - 4e-05 23.7 31.1 0.15 12.3 0.0 6.6 6 1 1 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 Paf67 PF10255.9 CEG36792.1 - 0.00056 19.0 10.1 1.2 8.1 0.1 4.7 4 1 1 5 5 5 2 RNA polymerase I-associated factor PAF67 TPR_14 PF13428.6 CEG36792.1 - 0.0006 20.4 21.0 0.012 16.3 0.1 8.2 7 2 2 9 9 9 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CEG36792.1 - 0.0028 17.1 1.5 0.85 9.0 0.1 2.5 2 0 0 2 2 2 2 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 CEG36792.1 - 0.0055 16.7 5.0 0.38 10.9 0.5 4.4 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 CEG36792.1 - 0.0056 15.9 1.5 5.2 6.2 0.1 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CEG36792.1 - 0.0092 15.4 17.0 0.21 11.1 0.2 7.5 7 0 0 7 7 7 1 SHNi-TPR TPR_7 PF13176.6 CEG36792.1 - 0.02 14.9 18.3 0.24 11.5 0.1 8.0 8 1 1 9 9 7 0 Tetratricopeptide repeat MIT PF04212.18 CEG36792.1 - 0.024 14.7 12.8 13 6.0 0.0 6.4 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CEG36792.1 - 0.089 13.1 3.0 4.1 7.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF357 PF04010.13 CEG36792.1 - 6.1 7.0 8.4 12 6.1 0.2 4.0 4 1 1 5 5 4 0 Protein of unknown function (DUF357) TPR_4 PF07721.14 CEG36792.1 - 6.6 7.7 8.1 4.5 8.2 0.2 4.5 4 0 0 4 4 2 0 Tetratricopeptide repeat tRNA_synthFbeta PF17759.1 CEG36794.1 - 3.7e-46 157.3 0.0 6.8e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CEG36794.1 - 2.5e-34 117.3 0.1 7.2e-34 115.9 0.1 1.8 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CEG36794.1 - 7.4e-28 97.4 0.1 1.6e-27 96.3 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CEG36794.1 - 1.8e-11 44.2 0.1 5.2e-09 36.3 0.1 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF5082 PF16888.5 CEG36795.1 - 0.0087 16.3 6.5 0.0087 16.3 6.5 6.7 3 2 3 6 6 6 2 Domain of unknown function (DUF5082) DUF1652 PF07865.11 CEG36795.1 - 0.011 15.5 0.3 0.043 13.7 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) CENP-F_leu_zip PF10473.9 CEG36795.1 - 0.012 15.6 11.2 0.012 15.6 11.2 7.8 1 1 6 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 CEG36795.1 - 0.064 13.5 0.4 0.064 13.5 0.4 7.7 7 0 0 7 7 7 0 Homeobox associated leucine zipper Mce4_CUP1 PF11887.8 CEG36795.1 - 0.14 11.5 7.4 3.2 7.2 0.4 3.6 3 1 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3584 PF12128.8 CEG36795.1 - 0.15 9.6 93.6 0.13 9.7 4.7 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) ketoacyl-synt PF00109.26 CEG36796.1 - 5.2e-55 186.8 0.6 9.3e-55 185.9 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CEG36796.1 - 2.4e-34 117.9 1.0 2.4e-34 117.9 1.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CEG36796.1 - 0.0001 21.8 0.4 0.00017 21.0 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CEG36796.1 - 0.02 14.7 0.3 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myotub-related PF06602.14 CEG36798.1 - 5.9e-126 420.1 0.0 8.4e-126 419.6 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 CEG36798.1 - 6.2e-30 104.5 1.2 9.6e-28 97.3 1.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PDZ PF00595.24 CEG36798.1 - 0.00029 21.1 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain 3-PAP PF12578.8 CEG36798.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein Y_phosphatase3 PF13350.6 CEG36798.1 - 0.043 13.8 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 CEG36798.1 - 0.077 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 GRAM domain PDZ_6 PF17820.1 CEG36798.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain CoA_transf_3 PF02515.17 CEG36799.1 - 5.1e-112 374.6 0.1 8.3e-112 373.9 0.0 1.4 2 0 0 2 2 2 1 CoA-transferase family III zinc_ribbon_9 PF14369.6 CEG36801.1 - 6.4e-08 32.7 5.9 6.4e-08 32.7 5.9 2.6 2 1 0 2 2 2 1 zinc-ribbon HypA PF01155.19 CEG36801.1 - 0.0037 17.3 6.9 0.3 11.1 1.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 CEG36801.1 - 0.016 15.0 2.1 0.016 15.0 2.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CEG36801.1 - 0.17 11.7 0.5 0.17 11.7 0.5 3.3 4 0 0 4 4 4 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 CEG36801.1 - 1.7 8.7 7.0 38 4.3 0.4 3.5 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zinc-ribbons_6 PF07191.12 CEG36801.1 - 4.8 7.2 10.3 11 6.0 1.6 2.3 2 0 0 2 2 2 0 zinc-ribbons DpnI_C PF17726.1 CEG36802.1 - 0.013 15.7 0.1 7.1 6.8 0.1 2.8 2 0 0 2 2 2 0 Dam-replacing HTH domain Mei5_like PF17021.5 CEG36802.1 - 0.076 13.1 0.2 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Putative double-strand recombination repair-like EZH2_N PF18601.1 CEG36802.1 - 0.081 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 EZH2 N-terminal domain DUF3950 PF13132.6 CEG36802.1 - 0.12 12.1 0.2 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) PAP_assoc PF03828.19 CEG36803.1 - 1.3e-12 47.8 0.0 3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEG36803.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CEG36803.1 - 0.079 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PDZ_6 PF17820.1 CEG36804.1 - 7.1e-09 35.4 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG36804.1 - 1.2e-06 28.8 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CEG36804.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PUB PF09409.10 CEG36805.1 - 9.3e-15 54.3 0.0 1.9e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 CEG36805.1 - 2.7e-13 49.5 0.1 4.7e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CEG36805.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEG36805.1 - 0.0059 17.2 0.3 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CEG36805.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 CEG36805.1 - 0.1 12.4 31.1 2.3 8.0 15.1 3.9 2 1 1 3 3 3 0 XPC-binding domain STI1 PF17830.1 CEG36805.1 - 0.12 12.4 26.2 1.5 8.8 21.7 2.7 1 1 1 2 2 2 0 STI1 domain Bep_C_terminal PF17841.1 CEG36805.1 - 0.16 12.2 0.5 0.58 10.4 0.2 2.1 1 1 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) GerD PF17898.1 CEG36805.1 - 0.46 10.4 8.4 1.3 9.0 8.4 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain ARS2 PF04959.13 CEG36805.1 - 5.6 7.3 5.4 5.8 7.2 4.3 1.5 1 1 0 1 1 1 0 Arsenite-resistance protein 2 PDGF_N PF04692.13 CEG36807.1 - 0.1 13.4 0.0 0.27 12.1 0.0 1.7 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Retrotran_gag_2 PF14223.6 CEG36809.1 - 4.6e-10 39.3 0.0 6.2e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG36809.1 - 1.6e-07 31.1 1.8 1.6e-07 31.1 1.8 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG36809.1 - 0.0017 18.2 2.2 0.0028 17.4 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEG36809.1 - 0.039 13.9 0.4 0.071 13.1 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle DHHC PF01529.20 CEG36810.1 - 1.3e-34 119.2 7.3 1.3e-34 119.2 7.3 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAP_fibrillin PF04755.12 CEG36810.1 - 0.044 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 PAP_fibrillin TMEM100 PF16311.5 CEG36810.1 - 0.51 9.9 4.1 0.14 11.7 0.4 1.9 2 0 0 2 2 2 0 Transmembrane protein 100 Methyltransf_16 PF10294.9 CEG36811.1 - 8.8e-23 80.9 0.5 5.7e-14 52.2 0.1 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Ank_2 PF12796.7 CEG36811.1 - 4.4e-15 56.0 0.4 3.7e-14 53.1 0.2 2.5 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG36811.1 - 8.9e-13 48.5 0.2 1.8e-11 44.3 0.2 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG36811.1 - 2.2e-12 47.0 1.3 7.3e-06 26.2 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG36811.1 - 6.2e-12 45.4 0.5 2.2e-05 24.7 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG36811.1 - 3.8e-11 42.2 0.2 0.00016 21.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.18 CEG36811.1 - 5.5e-10 39.2 13.9 1.6e-09 37.7 13.9 1.9 1 0 0 1 1 1 1 MYND finger Met_10 PF02475.16 CEG36811.1 - 2.6e-05 24.1 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CEG36811.1 - 0.00019 21.1 0.3 0.0043 16.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CEG36811.1 - 0.00082 19.2 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG36811.1 - 0.0019 17.7 0.2 0.0048 16.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) zf-C6H2 PF15801.5 CEG36811.1 - 0.0057 16.9 4.3 0.016 15.5 4.3 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Methyltransf_12 PF08242.12 CEG36811.1 - 0.026 15.3 0.1 2.7 8.8 0.0 2.5 1 1 0 2 2 2 0 Methyltransferase domain TFIIE_alpha PF02002.17 CEG36811.1 - 0.029 14.2 0.4 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 TFIIE alpha subunit Arm-DNA-bind_5 PF17293.2 CEG36811.1 - 0.08 13.4 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain Methyltransf_25 PF13649.6 CEG36811.1 - 0.085 13.6 0.2 2.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_S8 PF00082.22 CEG36812.1 - 2.7e-36 125.4 0.7 5.6e-36 124.3 0.7 1.5 1 1 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy_3 PF13640.6 CEG36813.1 - 0.12 13.3 1.5 0.29 12.1 0.3 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MCM PF00493.23 CEG36814.1 - 3.9e-102 340.1 0.1 7.3e-102 339.2 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEG36814.1 - 4.3e-32 110.6 1.0 1.2e-31 109.1 0.4 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CEG36814.1 - 1.2e-19 70.5 0.6 6.1e-19 68.2 0.6 2.3 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEG36814.1 - 1.5e-13 51.2 0.0 4.9e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEG36814.1 - 1.1e-07 31.4 0.4 6.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEG36814.1 - 1.6e-05 24.9 0.1 6.1e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CEG36814.1 - 5.6e-05 23.0 0.1 0.00017 21.4 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CEG36814.1 - 0.0097 15.7 0.1 0.033 14.0 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 CEG36814.1 - 0.013 15.9 0.4 0.046 14.1 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CEG36814.1 - 0.013 15.9 0.1 0.051 14.0 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 CEG36814.1 - 0.052 14.2 0.3 0.25 12.0 0.3 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 CEG36814.1 - 0.13 11.9 0.1 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain FAD_binding_8 PF08022.12 CEG36816.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 FAD-binding domain RVT_2 PF07727.14 CEG36818.1 - 5.3e-23 81.9 0.0 7.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transgly PF00912.22 CEG36818.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase GRIP PF01465.20 CEG36819.1 - 5.1e-18 64.7 0.6 1.2e-17 63.5 0.6 1.7 1 0 0 1 1 1 1 GRIP domain HMMR_N PF15905.5 CEG36819.1 - 0.0035 16.9 16.8 0.0035 16.9 16.8 4.6 2 1 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 CEG36819.1 - 0.0053 17.3 3.7 0.0053 17.3 3.7 10.3 7 4 3 10 10 10 1 SlyX YabA PF06156.13 CEG36819.1 - 0.013 16.1 5.7 0.013 16.1 5.7 8.0 3 1 4 7 7 7 0 Initiation control protein YabA Mod_r PF07200.13 CEG36819.1 - 0.016 15.3 10.4 0.016 15.3 10.4 6.4 2 1 5 7 7 7 0 Modifier of rudimentary (Mod(r)) protein GLE1 PF07817.13 CEG36819.1 - 0.041 13.1 0.3 0.041 13.1 0.3 3.1 3 0 0 3 3 3 0 GLE1-like protein Filament PF00038.21 CEG36819.1 - 0.76 9.3 71.2 0.83 9.2 14.3 5.3 2 1 2 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 CEG36819.1 - 0.91 8.3 77.4 0.49 9.2 14.0 5.6 2 1 4 6 6 6 0 Spc7 kinetochore protein GAS PF13851.6 CEG36819.1 - 2.7 7.3 78.6 0.3 10.4 0.5 5.4 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CEG36819.1 - 2.9 8.2 27.2 2.6 8.3 1.1 7.3 6 2 0 6 6 6 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 CEG36819.1 - 7 6.0 76.6 0.24 10.9 22.6 5.5 2 1 4 6 6 6 0 Golgin subfamily A member 5 WD40 PF00400.32 CEG36821.1 - 0.0072 17.2 9.2 3.2 8.8 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Nif11 PF07862.11 CEG36821.1 - 0.1 12.9 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Nif11 domain HflK_N PF12221.8 CEG36823.1 - 0.1 12.6 2.5 1.4 9.0 1.4 2.6 2 1 0 2 2 2 0 Bacterial membrane protein N terminal AAA_6 PF12774.7 CEG36824.1 - 3.2e-161 535.8 0.0 1.8e-159 530.0 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG36824.1 - 5.3e-125 417.6 5.9 5.3e-125 417.6 5.9 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG36824.1 - 7.3e-105 350.0 0.1 3.7e-104 347.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG36824.1 - 4.6e-95 318.4 0.0 4.2e-92 308.7 0.0 2.9 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG36824.1 - 3.1e-91 304.4 0.2 1.5e-90 302.2 0.3 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG36824.1 - 1.7e-67 226.4 0.1 4e-63 212.2 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG36824.1 - 5e-50 169.5 0.2 2.1e-49 167.5 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG36824.1 - 1.4e-46 157.5 0.0 6.1e-43 145.7 0.0 3.4 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CEG36824.1 - 6e-43 147.2 9.3 1.5e-42 145.9 9.3 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CEG36824.1 - 2.9e-21 75.5 0.2 6.6e-20 71.2 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CEG36824.1 - 6.8e-17 61.8 0.1 1.1e-05 25.5 0.0 6.8 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEG36824.1 - 1.1e-15 57.9 2.3 4.4e-08 33.3 0.3 3.4 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CEG36824.1 - 3.9e-08 33.7 0.3 0.16 12.2 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CEG36824.1 - 6e-07 30.0 1.0 0.9 9.9 0.0 5.1 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 CEG36824.1 - 8.8e-06 26.2 0.1 0.32 11.4 0.0 4.6 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEG36824.1 - 2.6e-05 24.6 1.8 2.7 8.4 0.0 5.0 5 0 0 5 5 4 1 RNA helicase AAA_18 PF13238.6 CEG36824.1 - 9.3e-05 23.0 0.0 0.49 10.9 0.0 3.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CEG36824.1 - 0.00013 22.1 0.3 0.93 9.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 CEG36824.1 - 0.00045 19.9 0.1 0.063 13.0 0.0 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.12 CEG36824.1 - 0.0018 18.2 0.0 2.1 8.2 0.0 3.6 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.26 CEG36824.1 - 0.0059 16.3 0.0 0.28 10.8 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 CEG36824.1 - 0.0089 15.8 0.2 4.9 6.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 CEG36824.1 - 0.01 16.4 0.0 0.99 9.9 0.0 3.6 3 0 0 3 3 2 0 ABC transporter T2SSE PF00437.20 CEG36824.1 - 0.01 14.9 0.4 1.6 7.7 0.0 3.5 4 0 0 4 4 3 0 Type II/IV secretion system protein TsaE PF02367.17 CEG36824.1 - 0.027 14.5 0.5 64 3.6 0.1 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CEG36824.1 - 0.065 13.5 0.1 1.9 8.7 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 CEG36824.1 - 0.074 12.8 0.0 14 5.4 0.1 2.8 2 0 0 2 2 2 0 Cytidylate kinase DUF87 PF01935.17 CEG36824.1 - 0.29 11.2 7.1 5.3 7.1 0.0 4.4 4 0 0 4 4 3 0 Helicase HerA, central domain Bromodomain PF00439.25 CEG36825.1 - 4e-17 62.1 0.0 6.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain ELH PF02323.15 CEG36825.1 - 0.045 13.1 0.6 0.067 12.6 0.6 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor PRF PF06875.11 CEG36825.1 - 0.079 12.4 0.1 0.099 12.1 0.1 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Pkinase PF00069.25 CEG36826.1 - 2.8e-25 89.2 0.0 4.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36826.1 - 2.4e-13 50.0 0.0 3.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DHC_N1 PF08385.12 CEG36827.1 - 1.4e-170 568.7 10.9 1.4e-170 568.7 10.9 1.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG36827.1 - 2.9e-134 447.2 0.0 1.4e-133 444.9 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG36827.1 - 2.3e-96 323.3 2.8 4.4e-59 200.6 0.1 5.1 5 1 1 6 6 5 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG36827.1 - 2.6e-83 279.3 0.0 9.5e-83 277.5 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG36827.1 - 2.1e-77 260.3 0.1 1.7e-76 257.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG36827.1 - 1.2e-70 237.0 0.0 7.7e-67 224.6 0.1 2.8 2 0 0 2 2 2 2 ATP-binding dynein motor region AAA_7 PF12775.7 CEG36827.1 - 2.2e-51 174.0 0.0 4.3e-46 156.7 0.0 4.3 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG36827.1 - 1.3e-45 155.1 0.0 3.8e-45 153.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG36827.1 - 1.5e-37 128.3 0.0 2.4e-36 124.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CEG36827.1 - 1.4e-34 119.7 9.9 3.7e-34 118.3 9.9 1.7 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CEG36827.1 - 2.5e-16 59.9 0.0 1.5e-15 57.4 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CEG36827.1 - 5.1e-16 58.9 0.1 8.3e-06 25.9 0.0 5.8 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CEG36827.1 - 4.2e-13 49.4 0.0 3.4e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CEG36827.1 - 8e-13 49.1 8.6 0.00023 21.6 0.0 6.2 5 0 0 5 5 4 3 AAA ATPase domain AAA PF00004.29 CEG36827.1 - 3.9e-11 43.5 1.0 0.12 12.9 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG36827.1 - 6.4e-07 29.7 10.1 0.06 13.6 0.0 5.9 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 CEG36827.1 - 2.1e-06 27.6 0.9 0.5 10.0 0.0 4.3 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 CEG36827.1 - 9.3e-05 21.7 0.1 0.84 8.7 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CEG36827.1 - 0.00011 22.4 0.6 6.3 7.0 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 CEG36827.1 - 0.00014 22.4 5.3 2.8 8.5 0.0 5.8 6 0 0 6 6 4 1 AAA domain ABC_tran PF00005.27 CEG36827.1 - 0.00016 22.2 1.4 2.1 8.8 0.0 4.0 4 0 0 4 4 3 2 ABC transporter AAA_19 PF13245.6 CEG36827.1 - 0.00022 21.6 2.2 1.8 8.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CEG36827.1 - 0.00046 19.9 0.3 3.1 7.6 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG36827.1 - 0.0045 16.9 0.5 3 7.7 0.0 3.2 3 0 0 3 3 2 1 RsgA GTPase TsaE PF02367.17 CEG36827.1 - 0.0054 16.7 1.6 15 5.6 0.0 3.9 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CEG36827.1 - 0.0054 16.1 0.1 17 4.7 0.0 3.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CEG36827.1 - 0.0062 16.9 0.0 14 6.1 0.0 3.8 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 CEG36827.1 - 0.014 14.8 0.4 7.8 5.8 0.1 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CEG36827.1 - 0.017 15.2 0.1 4.8 7.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CEG36827.1 - 0.019 14.3 0.1 11 5.3 0.0 3.1 3 0 0 3 3 2 0 Zeta toxin MCM PF00493.23 CEG36827.1 - 0.019 14.1 0.2 0.32 10.1 0.0 2.8 3 0 0 3 3 3 0 MCM P-loop domain Sigma54_activat PF00158.26 CEG36827.1 - 0.023 14.4 0.0 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 CEG36827.1 - 0.024 14.4 2.3 7.2 6.3 0.0 4.6 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 CEG36827.1 - 0.03 14.5 0.3 4.4 7.5 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3583 PF12126.8 CEG36827.1 - 0.063 12.7 0.0 0.063 12.7 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF3583) Rad17 PF03215.15 CEG36827.1 - 0.11 12.4 0.0 64 3.4 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 CEG36827.1 - 0.18 11.9 1.7 1 9.4 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain NACHT PF05729.12 CEG36827.1 - 0.46 10.4 6.2 6.7 6.6 0.0 4.9 6 0 0 6 6 4 0 NACHT domain DUF87 PF01935.17 CEG36827.1 - 0.6 10.2 6.8 6.7 6.7 0.0 4.6 4 0 0 4 4 4 0 Helicase HerA, central domain zf-RING_2 PF13639.6 CEG36830.1 - 1.1e-11 44.9 11.4 1.1e-11 44.9 11.4 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CEG36830.1 - 1.9e-07 31.3 10.6 4e-07 30.2 9.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG36830.1 - 4.3e-07 29.7 11.1 1.5e-06 27.9 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG36830.1 - 1.1e-05 25.0 8.2 3.9e-05 23.3 8.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEG36830.1 - 3.3e-05 23.6 6.7 7.2e-05 22.6 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG36830.1 - 7.2e-05 22.6 7.4 0.00021 21.1 7.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG36830.1 - 0.00042 20.1 9.3 0.0037 17.1 9.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG36830.1 - 0.00069 19.2 9.3 0.00069 19.2 9.3 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CEG36830.1 - 0.0049 16.9 7.3 0.016 15.2 7.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CEG36830.1 - 0.011 15.7 8.5 0.011 15.7 8.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 CEG36830.1 - 0.44 10.7 10.1 0.21 11.8 3.9 2.3 1 1 1 2 2 2 0 PHD-zinc-finger like domain Anophelin PF10731.9 CEG36830.1 - 0.74 9.7 3.4 3.5 7.5 3.4 2.1 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito zf-RING_UBOX PF13445.6 CEG36830.1 - 0.9 9.6 13.5 0.1 12.7 7.8 2.5 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 CEG36830.1 - 1.9 8.6 9.0 6.2 7.0 9.0 2.0 1 0 0 1 1 1 0 Zinc-finger PX PF00787.24 CEG36832.1 - 1.3e-07 31.6 1.4 1.9e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 PX domain Gmx_para_CXXCG PF09535.10 CEG36832.1 - 0.019 14.3 0.0 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Zn-ribbon_8 PF09723.10 CEG36832.1 - 0.052 13.7 0.1 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF2072 PF09845.9 CEG36832.1 - 1.7 8.9 6.5 31 4.8 6.4 2.5 1 1 0 1 1 1 0 Zn-ribbon containing protein Abhydrolase_1 PF00561.20 CEG36833.1 - 4.4e-18 65.8 0.1 1.8e-13 50.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG36833.1 - 2.2e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG36833.1 - 9.1e-11 42.8 0.1 1.3e-10 42.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CEG36833.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 CEG36833.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 CEG36833.1 - 0.12 11.8 0.1 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CEG36834.1 - 1.4e-14 54.3 0.1 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG36834.1 - 1.4e-07 31.0 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG36834.1 - 2.3e-06 28.4 0.0 3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CEG36834.1 - 0.00033 20.4 0.7 0.00054 19.7 0.7 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 CEG36834.1 - 0.00071 19.2 0.1 0.68 9.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 CEG36834.1 - 0.0034 17.5 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein FAM177 PF14774.6 CEG36834.1 - 0.028 14.8 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 FAM177 family Peptidase_S15 PF02129.18 CEG36834.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 CEG36834.1 - 0.083 12.7 0.1 4.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GHMP_kinases_N PF00288.26 CEG36835.1 - 0.023 14.9 0.1 0.087 13.1 0.1 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain HAD_2 PF13419.6 CEG36836.1 - 8e-15 55.4 0.0 1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEG36836.1 - 7.7e-12 45.9 0.0 1.1e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG36836.1 - 0.0007 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HSP70 PF00012.20 CEG36840.1 - 7.9e-138 460.3 1.8 2e-137 459.0 1.8 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG36840.1 - 1.4e-05 24.1 0.0 3.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 MreB/Mbl protein LytR_cpsA_psr PF03816.14 CEG36840.1 - 0.00025 21.3 0.1 0.00064 19.9 0.1 1.7 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Zincin_2 PF10103.9 CEG36840.1 - 0.018 14.3 0.0 0.87 8.8 0.0 2.4 2 0 0 2 2 2 0 Zincin-like metallopeptidase LSM PF01423.22 CEG36841.1 - 1.1e-17 63.4 0.2 1.5e-17 63.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain F-box-like PF12937.7 CEG36842.1 - 7.5e-05 22.5 0.2 7.5e-05 22.5 0.2 1.8 2 0 0 2 2 2 1 F-box-like DUF4595 PF15283.6 CEG36842.1 - 0.00013 22.1 0.0 0.00014 22.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4595) with porin-like fold F-box_4 PF15966.5 CEG36842.1 - 0.04 13.8 0.7 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 F-box F-box PF00646.33 CEG36842.1 - 0.067 13.1 0.2 0.22 11.4 0.2 2.0 1 1 0 1 1 1 0 F-box domain Pkinase PF00069.25 CEG36844.1 - 1.2e-69 234.7 0.0 1.8e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36844.1 - 9e-32 110.4 0.0 1.7e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG36844.1 - 1.3e-10 41.7 0.1 3.6e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG36844.1 - 6.1e-05 23.4 1.8 0.00078 19.8 1.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 CEG36844.1 - 0.003 17.8 0.0 0.0093 16.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 CEG36844.1 - 0.013 14.5 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG36844.1 - 0.022 14.1 0.2 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SnoaL_2 PF12680.7 CEG36844.1 - 0.023 15.3 0.1 0.064 13.9 0.1 1.8 1 0 0 1 1 1 0 SnoaL-like domain Tub PF01167.18 CEG36845.1 - 1.8e-91 306.2 0.0 3.3e-91 305.3 0.0 1.4 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CEG36845.1 - 0.007 16.0 0.2 0.031 13.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3527) CTD_bind PF04818.13 CEG36846.1 - 7.2e-11 42.8 1.4 8.2e-10 39.4 0.1 3.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Saccharop_dh_N PF04455.12 CEG36846.1 - 0.12 12.7 2.2 2.3 8.7 0.1 3.2 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region DUF4140 PF13600.6 CEG36846.1 - 0.31 11.5 2.9 0.92 10.0 2.9 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CREPT PF16566.5 CEG36846.1 - 6.6 6.9 10.4 2.9 8.1 1.1 3.4 3 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DZR PF12773.7 CEG36847.1 - 9.1e-06 25.6 19.2 0.01 15.8 2.6 3.3 3 1 0 3 3 3 2 Double zinc ribbon zf-RanBP PF00641.18 CEG36847.1 - 0.00063 19.0 2.5 0.00063 19.0 2.5 4.8 5 0 0 5 5 5 2 Zn-finger in Ran binding protein and others HalX PF08663.10 CEG36847.1 - 0.014 15.7 0.5 0.029 14.7 0.3 1.6 2 0 0 2 2 2 0 HalX domain DUF2318 PF10080.9 CEG36847.1 - 2.1 8.5 15.6 0.43 10.7 0.4 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2318) Put_Phosphatase PF06888.12 CEG36849.1 - 0.081 12.3 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase AAA_28 PF13521.6 CEG36850.1 - 2.8e-23 82.9 0.0 4.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CEG36850.1 - 0.00025 20.1 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 CEG36850.1 - 0.0015 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DAP3 PF10236.9 CEG36850.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 CEG36850.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CEG36851.1 - 1.7e-44 152.1 0.0 6.4e-44 150.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36851.1 - 1.1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF547 PF04784.14 CEG36851.1 - 7.7e-24 84.1 0.0 1.5e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Kinase-like PF14531.6 CEG36851.1 - 4.7e-06 26.1 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DEP PF00610.21 CEG36851.1 - 0.0008 19.4 0.1 0.049 13.7 0.0 3.0 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase_fungal PF17667.1 CEG36851.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NIF PF03031.18 CEG36853.1 - 4.1e-23 81.9 0.0 5.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-RING_2 PF13639.6 CEG36856.1 - 4.8e-14 52.4 4.9 1.5e-13 50.8 4.9 1.9 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 CEG36856.1 - 4.9e-13 48.9 0.0 9.1e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 CEG36856.1 - 1.2e-11 44.2 4.2 1.2e-11 44.2 4.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG36856.1 - 9.1e-10 38.1 3.7 9.1e-10 38.1 3.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CEG36856.1 - 5e-09 36.3 2.7 1.5e-08 34.7 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG36856.1 - 5.9e-09 35.7 2.2 5.9e-09 35.7 2.2 2.0 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG36856.1 - 1.7e-07 31.0 2.5 3.6e-07 30.0 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG36856.1 - 2.3e-07 30.7 3.4 2.4e-07 30.7 1.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG36856.1 - 2.3e-06 27.4 1.1 5.5e-06 26.1 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG36856.1 - 3.1e-06 27.2 0.9 7.3e-06 26.0 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEG36856.1 - 5.1e-05 23.0 4.6 0.00013 21.7 4.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CEG36856.1 - 0.00032 20.5 6.5 0.041 13.8 7.2 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG36856.1 - 0.00086 19.4 4.3 0.002 18.2 4.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 CEG36856.1 - 0.071 13.3 2.3 0.083 13.1 0.1 2.2 3 0 0 3 3 3 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 CEG36856.1 - 0.11 12.2 3.5 0.14 11.8 2.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CEG36856.1 - 0.18 12.0 4.9 3.3 8.0 4.9 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CEG36856.1 - 0.2 11.5 2.9 0.58 10.1 2.9 1.9 1 0 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.14 CEG36856.1 - 0.22 11.4 2.0 11 5.9 0.4 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.7 CEG36856.1 - 0.65 10.2 3.3 0.84 9.8 1.1 2.4 2 1 0 2 2 1 0 RING-variant domain Prok-RING_1 PF14446.6 CEG36856.1 - 3.3 7.7 6.4 16 5.5 6.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RSN1_7TM PF02714.15 CEG36857.1 - 2.1e-29 102.7 20.8 2.1e-29 102.7 20.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEG36857.1 - 8.5e-14 51.6 0.4 8.5e-14 51.6 0.4 2.6 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEG36857.1 - 8.7e-06 26.1 0.1 0.0008 19.7 0.1 2.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Ax_dynein_light PF10211.9 CEG36858.1 - 2.6e-06 27.5 3.2 2.6e-06 27.5 3.2 2.4 2 0 0 2 2 2 1 Axonemal dynein light chain HALZ PF02183.18 CEG36858.1 - 0.15 12.3 2.4 0.51 10.6 2.4 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper WHIM1 PF15612.6 CEG36859.1 - 7.6e-07 28.5 0.2 1.8e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 TP2 PF01254.18 CEG36859.1 - 0.32 11.6 2.6 0.61 10.7 2.6 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 PIN_2 PF10130.9 CEG36859.1 - 1.5 9.0 6.2 3.5 7.9 5.7 1.9 1 1 0 1 1 1 0 PIN domain DNA_pol_A_exo1 PF01612.20 CEG36860.1 - 7.7e-40 136.5 1.2 1.7e-39 135.3 1.2 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CEG36860.1 - 1.6e-12 47.2 0.1 4.5e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CEG36860.1 - 6.5e-05 23.6 3.3 0.00012 22.7 0.2 2.8 2 0 0 2 2 2 1 PMC2NT (NUC016) domain Flagellin_C PF00700.21 CEG36860.1 - 0.004 17.5 0.7 0.87 10.0 0.2 2.7 2 0 0 2 2 2 2 Bacterial flagellin C-terminal helical region CHASE2 PF05226.11 CEG36860.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 CHASE2 domain OTCace PF00185.24 CEG36868.1 - 1.9e-52 177.5 0.1 2.8e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CEG36868.1 - 5.7e-41 140.0 0.0 9.4e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DHC_N1 PF08385.12 CEG36869.1 - 2.4e-186 620.7 1.2 2.4e-186 620.7 1.2 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG36869.1 - 4.5e-125 417.0 3.6 8.2e-61 205.8 0.0 4.4 4 1 1 5 5 5 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG36869.1 - 7.6e-114 380.9 13.6 7.6e-114 380.9 13.6 3.7 2 1 1 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG36869.1 - 1.8e-91 306.1 0.0 1.1e-90 303.5 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG36869.1 - 7.4e-87 291.4 1.1 1.5e-86 290.4 0.1 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG36869.1 - 2.2e-79 265.7 2.5 2.2e-79 265.7 2.5 3.3 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG36869.1 - 6.1e-69 231.1 0.3 1.3e-62 210.6 0.1 4.0 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 CEG36869.1 - 1.1e-66 225.2 13.6 1.1e-66 225.2 13.6 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CEG36869.1 - 1.6e-43 148.4 0.0 3.5e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG36869.1 - 2.3e-36 124.5 0.0 2e-35 121.5 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CEG36869.1 - 9.4e-25 87.2 0.3 5.2e-10 39.5 0.0 5.9 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEG36869.1 - 4e-22 78.7 0.0 2e-21 76.4 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG36869.1 - 5.6e-22 77.8 0.1 3.2e-21 75.4 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CEG36869.1 - 3.2e-08 34.1 0.7 1.3 9.5 0.0 5.8 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG36869.1 - 9.1e-07 29.5 0.0 0.069 13.7 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CEG36869.1 - 2.8e-06 27.2 3.7 0.39 10.4 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CEG36869.1 - 3.5e-06 27.5 3.0 0.016 15.6 0.0 5.4 5 0 0 5 5 4 1 AAA ATPase domain AAA_28 PF13521.6 CEG36869.1 - 1.3e-05 25.5 0.1 6.6 7.0 0.0 5.0 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 CEG36869.1 - 3.3e-05 24.2 0.1 0.036 14.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CEG36869.1 - 7e-05 23.2 0.1 0.16 12.3 0.0 3.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CEG36869.1 - 0.00018 21.8 0.2 3.2 8.2 0.0 4.2 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 CEG36869.1 - 0.00025 21.0 0.1 1.2 9.0 0.0 3.5 3 0 0 3 3 3 2 NACHT domain Rad17 PF03215.15 CEG36869.1 - 0.00041 20.3 0.0 0.21 11.5 0.0 4.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_25 PF13481.6 CEG36869.1 - 0.0015 18.1 4.6 1.1 8.8 0.0 4.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 CEG36869.1 - 0.0045 16.1 1.3 0.6 9.1 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.6 CEG36869.1 - 0.0063 16.5 0.0 0.12 12.4 0.0 3.3 4 0 0 4 4 2 1 AAA domain BCDHK_Adom3 PF10436.9 CEG36869.1 - 0.01 15.7 0.1 0.1 12.4 0.1 2.8 3 0 0 3 3 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Roc PF08477.13 CEG36869.1 - 0.015 15.6 2.2 0.049 13.8 0.0 3.2 3 0 0 3 3 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CEG36869.1 - 0.018 14.7 0.0 4 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 CEG36869.1 - 0.026 14.0 0.1 0.21 11.0 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.6 CEG36869.1 - 0.06 13.5 4.9 0.49 10.5 0.0 4.3 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 CEG36869.1 - 0.062 12.9 2.7 6.1 6.4 0.0 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain TsaE PF02367.17 CEG36869.1 - 0.066 13.2 0.3 18 5.3 0.0 3.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ras PF00071.22 CEG36869.1 - 0.067 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Ras family CBAH PF02275.18 CEG36869.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family PduV-EutP PF10662.9 CEG36869.1 - 0.097 12.4 0.5 24 4.7 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CEG36869.1 - 0.24 11.9 6.9 0.26 11.8 0.0 3.9 4 0 0 4 4 2 0 ABC transporter FPN1 PF06963.12 CEG36869.1 - 0.24 9.9 0.5 0.52 8.8 0.5 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Autophagy_N PF03986.13 CEG36870.1 - 3.5e-43 146.8 0.7 5.4e-43 146.2 0.1 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CEG36870.1 - 3.9e-17 62.6 1.6 9.2e-17 61.4 1.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CEG36870.1 - 5.2e-14 51.4 3.0 9.2e-14 50.7 3.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF3597 PF12200.8 CEG36871.1 - 0.019 15.5 0.2 4.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Ras PF00071.22 CEG36872.1 - 5.2e-56 188.7 0.0 6.3e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG36872.1 - 8.5e-31 106.7 0.2 1.8e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG36872.1 - 2.6e-12 46.6 0.0 3.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEG36872.1 - 7.5e-06 25.6 0.1 6.2e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG36872.1 - 1.5e-05 25.0 0.0 2.6e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEG36872.1 - 0.0035 16.7 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG36872.1 - 0.0045 16.9 0.0 1.1 9.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 CEG36872.1 - 0.018 14.8 0.3 0.061 13.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 CEG36872.1 - 0.051 13.4 0.3 0.18 11.6 0.3 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Dynamin_N PF00350.23 CEG36872.1 - 0.055 13.5 0.0 4.9 7.2 0.0 2.5 2 1 0 2 2 2 0 Dynamin family DUF501 PF04417.12 CEG36873.1 - 1.7e-42 144.5 0.4 2.2e-42 144.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF501) MukF_C PF17193.4 CEG36873.1 - 0.028 14.6 0.2 0.04 14.1 0.2 1.4 1 0 0 1 1 1 0 MukF C-terminal domain TPR_1 PF00515.28 CEG36874.1 - 5.5e-16 57.6 9.2 7.1e-06 25.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36874.1 - 1.2e-11 43.8 7.4 0.00015 21.6 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36874.1 - 5e-07 30.1 0.4 5.6e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36874.1 - 6.9e-05 23.0 1.7 0.11 13.0 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36874.1 - 7.1e-05 22.4 3.2 0.017 14.8 1.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CEG36874.1 - 0.00014 21.8 4.6 0.24 11.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36874.1 - 0.00015 21.9 0.1 0.00044 20.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG36874.1 - 0.00021 21.9 0.0 0.0049 17.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG36874.1 - 0.00028 20.7 1.4 0.27 11.3 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36874.1 - 0.0025 18.1 0.8 0.0025 18.1 0.8 3.2 3 1 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG36874.1 - 0.036 14.3 3.3 0.1 12.8 1.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CEG36874.1 - 0.1 12.7 1.1 2.3 8.3 0.1 2.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MitMem_reg PF13012.6 CEG36874.1 - 0.14 12.6 2.5 5.6 7.4 0.6 3.7 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Ank_4 PF13637.6 CEG36876.1 - 4.5e-08 33.5 0.2 0.00032 21.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG36876.1 - 5.7e-07 30.0 0.0 1.3e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG36876.1 - 8.3e-07 29.2 0.1 2e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG36876.1 - 9.5e-06 25.8 1.8 0.00059 20.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CEG36876.1 - 0.00017 21.8 0.4 0.2 12.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat MinC_N PF05209.13 CEG36876.1 - 0.063 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF1515 PF07439.11 CEG36876.1 - 1.1 9.3 9.2 35 4.5 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) ParcG PF10274.9 CEG36877.1 - 3.6e-71 239.1 0.0 7.8e-71 238.0 0.0 1.6 1 0 0 1 1 1 1 Parkin co-regulated protein LRR_6 PF13516.6 CEG36877.1 - 7.7e-09 34.9 26.8 0.25 11.5 0.1 9.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 CEG36877.1 - 4e-06 27.1 15.4 2.1 8.9 0.3 6.7 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) DCB PF16213.5 CEG36877.1 - 0.043 13.5 0.0 0.043 13.5 0.0 3.1 3 1 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF726 PF05277.12 CEG36878.1 - 3e-17 62.6 0.1 2.8e-11 43.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Lipase_3 PF01764.25 CEG36878.1 - 0.0074 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CEG36878.1 - 0.045 13.3 0.2 0.086 12.3 0.2 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) TPR_2 PF07719.17 CEG36879.1 - 2.9e-12 45.7 4.0 0.00027 20.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG36879.1 - 3.6e-09 36.0 4.7 0.00017 21.3 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36879.1 - 6.2e-08 33.0 2.3 1.9e-06 28.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG36879.1 - 8.4e-08 32.4 1.1 0.21 12.3 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG36879.1 - 2.2e-07 31.0 2.0 1.3e-06 28.6 0.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CEG36879.1 - 1e-06 29.0 0.2 0.019 15.7 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36879.1 - 4.5e-06 26.7 0.3 2e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36879.1 - 6.1e-06 26.1 2.1 0.16 12.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36879.1 - 1.8e-05 24.8 0.5 0.52 10.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG36879.1 - 0.00019 21.4 2.9 0.15 12.1 0.0 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEG36879.1 - 0.00081 19.3 0.1 2.9 8.1 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36879.1 - 0.00081 19.6 0.3 0.74 10.1 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG36879.1 - 0.0057 16.1 2.3 0.015 14.7 2.3 1.8 1 1 0 1 1 1 1 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 CEG36879.1 - 0.014 15.8 0.5 0.55 10.7 0.2 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_16 PF13432.6 CEG36879.1 - 0.025 15.2 1.7 9.6 7.0 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEG36879.1 - 0.05 13.6 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat Mito_carr PF00153.27 CEG36880.1 - 4.1e-50 167.7 6.8 9e-18 64.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M1 PF01433.20 CEG36882.1 - 5.3e-49 166.7 0.1 8.9e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CEG36882.1 - 4.8e-27 94.3 0.0 1.2e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CEG36882.1 - 3.1e-21 76.4 0.2 6.4e-21 75.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Voltage_CLC PF00654.20 CEG36884.1 - 2.4e-87 293.5 30.4 2.4e-87 293.5 30.4 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CEG36884.1 - 2.6e-06 27.8 0.0 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 CBS domain UEV PF05743.13 CEG36885.1 - 1.6e-32 111.9 0.3 3.4e-32 110.9 0.3 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CEG36885.1 - 3e-10 39.9 1.8 3.3e-09 36.6 0.1 3.3 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 CEG36885.1 - 1.3e-05 24.9 0.5 6.7e-05 22.6 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme gpW PF02831.15 CEG36885.1 - 0.064 13.2 0.9 0.26 11.2 0.9 2.0 1 0 0 1 1 1 0 gpW Exonuc_VII_S PF02609.16 CEG36885.1 - 0.2 11.7 3.3 3.2 7.9 0.1 3.3 2 0 0 2 2 2 0 Exonuclease VII small subunit Sld5 PF05916.11 CEG36885.1 - 1.9 9.0 12.6 2.3 8.7 0.0 4.3 4 1 1 5 5 5 0 GINS complex protein Ion_trans PF00520.31 CEG36886.1 - 9.3e-22 77.4 14.1 1.3e-21 76.9 14.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEG36886.1 - 9.9e-15 54.3 6.2 9.9e-15 54.3 6.2 2.5 2 1 1 3 3 3 1 Ion channel PKD_channel PF08016.12 CEG36886.1 - 8.2e-05 21.4 2.1 0.00015 20.6 2.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel DZR PF12773.7 CEG36886.1 - 0.00068 19.6 0.7 0.0011 18.9 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEG36886.1 - 0.0015 18.2 1.0 0.0033 17.1 1.0 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEG36886.1 - 0.045 13.2 0.3 0.099 12.1 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 CEG36886.1 - 0.065 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_1 PF14446.6 CEG36886.1 - 0.13 12.3 0.6 0.22 11.5 0.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Lig_chan PF00060.26 CEG36886.1 - 0.94 9.3 3.4 15 5.4 0.0 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel SCAMP PF04144.13 CEG36886.1 - 1.8 8.8 6.6 11 6.2 1.2 2.3 2 0 0 2 2 2 0 SCAMP family DUF2434 PF10361.9 CEG36886.1 - 5.7 5.8 6.8 12 4.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) PH PF00169.29 CEG36887.1 - 0.016 15.7 0.1 0.031 14.8 0.1 1.5 1 1 0 1 1 1 0 PH domain DUF5482 PF17579.2 CEG36887.1 - 0.2 11.5 0.0 0.48 10.3 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5482) AAA_18 PF13238.6 CEG36888.1 - 6.6e-05 23.5 2.2 0.0002 21.9 0.4 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CEG36888.1 - 0.00028 20.2 0.0 0.00074 18.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 CEG36888.1 - 0.00043 20.6 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG36888.1 - 0.0012 19.0 1.5 0.01 16.0 1.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG36888.1 - 0.0045 17.4 0.1 0.0045 17.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 CEG36888.1 - 0.0075 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 CEG36888.1 - 0.015 15.2 1.7 0.11 12.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase CbiA PF01656.23 CEG36888.1 - 0.016 15.3 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CEG36888.1 - 0.018 14.9 0.0 0.071 13.0 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CEG36888.1 - 0.021 14.4 1.5 0.093 12.3 0.9 2.4 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CEG36888.1 - 0.027 14.4 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CEG36888.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CEG36888.1 - 0.069 13.6 0.2 0.26 11.7 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CEG36888.1 - 0.16 12.5 2.1 0.33 11.5 0.0 2.6 4 0 0 4 4 3 0 ABC transporter CENP-B_dimeris PF09026.10 CEG36888.1 - 3.2 8.2 14.5 8.5 6.8 11.9 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIA PF03153.13 CEG36888.1 - 5.6 6.8 17.8 7.9 6.4 1.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_1 PF00515.28 CEG36889.1 - 1.3e-15 56.5 0.0 0.00031 20.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG36889.1 - 4.3e-15 54.6 0.0 0.00042 20.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG36889.1 - 6.2e-15 54.0 0.0 0.0035 17.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG36889.1 - 1.7e-14 53.2 0.0 9.6e-08 31.6 0.0 2.8 2 1 1 3 3 3 2 TPR repeat FYVE PF01363.21 CEG36889.1 - 5.1e-13 49.0 9.9 9.5e-13 48.1 9.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger TPR_16 PF13432.6 CEG36889.1 - 1.6e-10 41.5 3.2 5.6e-06 26.9 0.0 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG36889.1 - 1.7e-09 37.9 0.0 7.2e-05 23.0 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG36889.1 - 2e-08 33.7 0.0 0.012 15.6 0.0 4.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG36889.1 - 6.7e-08 32.7 2.9 0.0026 18.4 0.0 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG36889.1 - 7.5e-08 32.8 1.2 1.6e-05 25.3 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG36889.1 - 3.5e-05 24.2 0.0 1.5 9.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CEG36889.1 - 0.001 18.8 0.1 0.0029 17.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEG36889.1 - 0.002 17.9 0.1 3.3 7.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG36889.1 - 0.0021 18.2 0.0 0.019 15.1 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG36889.1 - 0.0028 17.9 0.0 0.84 10.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_5 PF13857.6 CEG36889.1 - 0.026 14.8 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) OrfB_Zn_ribbon PF07282.11 CEG36889.1 - 0.043 13.7 1.9 0.1 12.5 1.9 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ANAPC3 PF12895.7 CEG36889.1 - 0.16 12.2 0.0 0.6 10.4 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2180 PF09947.9 CEG36889.1 - 2.4 8.2 5.2 9.3 6.3 5.2 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) RWP-RK PF02042.15 CEG36892.1 - 5.7e-13 48.6 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain UPF0121 PF03661.13 CEG36892.1 - 0.0026 17.2 0.1 0.0039 16.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HTH_6 PF01418.17 CEG36892.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family NUMOD1 PF07453.13 CEG36892.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain HTH_8 PF02954.19 CEG36892.1 - 0.16 11.8 0.1 0.48 10.2 0.0 1.9 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family DUF1084 PF06454.11 CEG36893.1 - 8e-07 28.7 4.6 1.9e-06 27.5 4.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) MIG-14_Wnt-bd PF06664.12 CEG36893.1 - 0.11 11.7 5.0 0.21 10.8 5.0 1.5 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Iso_dh PF00180.20 CEG36894.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.3 1 1 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Glyco_transf_4 PF13439.6 CEG36895.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CEG36895.1 - 6.2e-05 23.5 0.4 0.0031 17.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CEG36895.1 - 0.0002 20.9 0.1 0.14 11.7 0.1 2.3 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEG36895.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 Elicitin PF00964.17 CEG36896.1 - 1e-17 64.0 1.2 1e-17 64.0 1.2 1.9 1 1 1 2 2 2 1 Elicitin ATG7_N PF16420.5 CEG36899.1 - 1.1e-77 261.7 0.1 1.4e-77 261.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CEG36899.1 - 6.1e-49 166.6 0.0 1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CEG36899.1 - 0.0004 20.5 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CEG36899.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 CEG36899.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding EF-hand_1 PF00036.32 CEG36900.1 - 8.4e-22 75.0 0.6 3.5e-06 26.2 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG36900.1 - 1e-21 77.1 1.6 3e-11 43.6 0.7 2.7 2 0 0 2 2 2 2 EF-hand domain pair FKBP_C PF00254.28 CEG36900.1 - 2.3e-21 75.9 0.0 5.3e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_6 PF13405.6 CEG36900.1 - 3.7e-16 57.6 0.5 8.2e-05 22.2 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG36900.1 - 8.9e-11 41.5 3.3 1.1e-05 25.2 1.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG36900.1 - 7.1e-10 37.9 2.2 0.00042 19.7 0.3 3.6 4 0 0 4 4 4 2 EF hand WW PF00397.26 CEG36900.1 - 1.8e-08 34.3 1.5 3.3e-08 33.5 1.5 1.4 1 0 0 1 1 1 1 WW domain SPARC_Ca_bdg PF10591.9 CEG36900.1 - 0.0026 18.1 9.3 0.13 12.6 0.1 3.6 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region IQ PF00612.27 CEG36900.1 - 0.082 12.7 1.9 0.19 11.6 1.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_9 PF14658.6 CEG36900.1 - 0.12 12.8 0.1 14 6.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain eRF1_2 PF03464.15 CEG36901.1 - 2.2e-44 151.0 0.0 3.5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEG36901.1 - 1.4e-37 128.6 0.0 2.8e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CEG36901.1 - 7.4e-19 68.0 0.0 1.6e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CEG36901.1 - 2.6e-10 40.7 0.0 3.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CEG36901.1 - 2.9e-09 37.3 0.0 4.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 CEG36901.1 - 0.099 12.4 0.0 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MoCF_biosynth PF00994.24 CEG36902.1 - 8.6e-61 203.8 0.3 7.1e-33 113.3 0.3 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CEG36902.1 - 1.5e-41 141.8 1.3 2.5e-41 141.1 1.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CEG36902.1 - 3.4e-14 52.8 0.0 8.5e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Rdx PF10262.9 CEG36903.1 - 1.2e-16 60.6 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Rdx family ZF-HD_dimer PF04770.12 CEG36903.1 - 0.059 13.7 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 ZF-HD protein dimerisation region CPT_N PF16484.5 CEG36904.1 - 0.12 12.4 0.6 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus B-block_TFIIIC PF04182.12 CEG36905.1 - 2.7e-09 37.0 0.2 2e-08 34.3 0.1 2.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC LRR_4 PF12799.7 CEG36906.1 - 2.2e-11 43.8 7.7 0.00026 21.3 0.1 4.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG36906.1 - 2.9e-10 39.9 4.3 1.4e-07 31.2 0.8 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CEG36906.1 - 6e-08 32.3 5.8 0.0026 17.5 0.0 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CEG36906.1 - 3.1e-05 23.7 12.4 6.1 7.2 0.0 6.4 5 1 1 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 CEG36906.1 - 0.038 14.5 8.1 3.3 8.6 0.1 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat Ank_2 PF12796.7 CEG36907.1 - 2.6e-06 27.9 1.0 0.00012 22.6 0.0 3.6 2 2 2 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG36907.1 - 6.8e-06 26.0 8.1 0.016 15.7 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CEG36907.1 - 1.8e-05 25.0 0.7 0.00026 21.2 0.1 3.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG36907.1 - 0.0013 19.1 3.3 0.016 15.6 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat DUF2920 PF11144.8 CEG36907.1 - 0.14 11.3 2.8 0.25 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Ank_4 PF13637.6 CEG36907.1 - 0.2 12.3 3.4 26 5.6 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeats (many copies) HECT PF00632.25 CEG36908.1 - 2.9e-59 201.0 0.0 9.2e-59 199.4 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Mod_r PF07200.13 CEG36909.1 - 2.3e-27 95.9 9.3 3.6e-27 95.3 9.3 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 CEG36909.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4795 PF16043.5 CEG36909.1 - 0.0027 17.3 1.4 0.0048 16.5 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Adap_comp_sub PF00928.21 CEG36910.1 - 4.5e-67 226.2 0.0 6.2e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEG36910.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 CEG36910.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Mon1 PF03164.14 CEG36910.1 - 0.068 12.2 0.0 0.098 11.7 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 MRP-S28 PF10213.9 CEG36911.1 - 4.1e-12 46.6 0.1 8e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein BCAS2 PF05700.11 CEG36912.1 - 2.1e-42 145.2 7.0 2.6e-42 144.9 7.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Cellulase PF00150.18 CEG36913.1 - 8.5e-30 104.1 0.3 1.2e-29 103.6 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PQQ PF01011.21 CEG36913.1 - 0.063 13.2 0.2 0.2 11.6 0.2 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Myb_DNA-bind_4 PF13837.6 CEG36915.1 - 1.5e-06 28.5 2.8 0.63 10.4 0.0 6.5 6 0 0 6 6 6 2 Myb/SANT-like DNA-binding domain RHH_4 PF13467.6 CEG36915.1 - 0.14 12.0 0.8 23 4.9 0.1 3.6 3 0 0 3 3 3 0 Ribbon-helix-helix domain DUF1451 PF07295.11 CEG36915.1 - 2 8.4 8.2 2.8 8.0 0.5 3.6 3 0 0 3 3 3 0 Zinc-ribbon containing domain WD40 PF00400.32 CEG36917.1 - 8.3e-55 181.5 16.6 3.8e-07 30.7 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36917.1 - 3.8e-15 56.0 0.2 0.0001 22.5 0.0 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEG36917.1 - 9.3e-07 27.9 0.1 0.0026 16.6 0.0 3.4 2 1 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 CEG36917.1 - 2.2e-06 26.6 0.5 0.11 11.1 0.1 4.1 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG36917.1 - 0.0019 17.3 0.3 0.061 12.3 0.3 3.0 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CEG36917.1 - 0.033 12.5 0.0 0.76 8.0 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA PF00004.29 CEG36918.1 - 6.2e-38 130.2 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ribosomal_S28e PF01200.18 CEG36918.1 - 2.9e-30 104.1 0.7 6.4e-30 102.9 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S28e AAA_lid_3 PF17862.1 CEG36918.1 - 1.4e-07 31.2 0.1 5e-07 29.4 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 CEG36918.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG36918.1 - 9.9e-05 22.6 0.3 0.02 15.2 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG36918.1 - 0.0015 19.0 0.5 0.034 14.6 0.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain LisH PF08513.11 CEG36918.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 LisH TIP49 PF06068.13 CEG36918.1 - 0.0032 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CEG36918.1 - 0.0033 16.9 0.0 0.0091 15.4 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CEG36918.1 - 0.0051 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CEG36918.1 - 0.0061 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEG36918.1 - 0.0062 16.9 0.0 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 CEG36918.1 - 0.012 15.6 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CEG36918.1 - 0.015 15.3 0.0 0.065 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CEG36918.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CEG36918.1 - 0.019 14.5 0.5 0.16 11.5 0.1 2.5 1 1 2 3 3 3 0 AAA domain AAA_24 PF13479.6 CEG36918.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG36918.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 CEG36918.1 - 0.042 13.7 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEG36918.1 - 0.051 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain LisH_TPL PF17814.1 CEG36918.1 - 0.066 12.9 0.3 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain AAA_18 PF13238.6 CEG36918.1 - 0.083 13.4 0.0 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG36918.1 - 0.16 11.5 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_C2 PF00648.21 CEG36919.1 - 3.7e-12 45.9 0.0 8.3e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease ARL2_Bind_BART PF11527.8 CEG36920.1 - 6.5e-11 42.4 0.2 1.3e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tn7_Tnp_TnsA_C PF08721.11 CEG36920.1 - 0.05 14.2 1.3 0.16 12.6 0.1 2.5 3 2 2 5 5 5 0 TnsA endonuclease C terminal Pribosyltran_N PF13793.6 CEG36922.1 - 2.8e-50 169.1 0.1 3.3e-49 165.7 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEG36922.1 - 3.9e-27 95.5 0.2 1.1e-26 94.0 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEG36922.1 - 2.6e-11 43.3 0.0 1e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEG36922.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase bZIP_1 PF00170.21 CEG36923.1 - 0.00012 22.1 8.7 0.00012 22.1 8.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEG36923.1 - 0.0012 18.8 9.3 0.0032 17.5 9.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEG36923.1 - 1.5 9.4 10.1 1.7 9.2 4.7 3.0 3 0 0 3 3 3 0 bZIP Maf transcription factor GATase PF00117.28 CEG36924.1 - 2.4e-50 171.0 0.0 2.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEG36924.1 - 0.00026 20.8 1.1 0.0016 18.2 1.1 1.9 1 1 0 1 1 1 1 Peptidase C26 XPG_N PF00752.17 CEG36927.1 - 2.7e-17 63.1 0.0 1.5e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CEG36927.1 - 2.1e-14 53.6 0.6 1.2e-13 51.2 0.1 2.5 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CEG36927.1 - 2.9e-07 30.2 0.1 2e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 XPG domain containing DUF3391 PF11871.8 CEG36927.1 - 0.0012 19.4 0.2 0.0033 17.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) UCH_C PF18031.1 CEG36927.1 - 3 7.8 7.5 1.2 9.1 2.0 2.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Isochorismatase PF00857.20 CEG36928.1 - 4.2e-26 92.2 0.1 1.1e-25 90.9 0.1 1.7 1 0 0 1 1 1 1 Isochorismatase family DUF2688 PF10892.8 CEG36928.1 - 0.038 13.5 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) DUF917 PF06032.12 CEG36928.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) GET2 PF08690.10 CEG36928.1 - 0.8 9.3 5.6 1.3 8.7 5.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Fer4_19 PF06902.11 CEG36929.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.5 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster ANAPC4_WD40 PF12894.7 CEG36931.1 - 0.011 16.0 0.7 7.9 6.9 0.0 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG36931.1 - 6.9 7.7 8.5 14 6.8 0.1 4.4 5 1 0 5 5 5 0 WD domain, G-beta repeat Vps35 PF03635.17 CEG36932.1 - 0.00017 20.3 2.8 0.0088 14.6 0.0 2.6 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Nup54 PF13874.6 CEG36933.1 - 1.3e-33 116.1 1.1 3.8e-33 114.6 0.8 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 CEG36933.1 - 0.0022 17.9 1.3 0.0046 16.8 1.3 1.5 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain ZnuA PF01297.17 CEG36933.1 - 0.016 14.7 0.4 0.023 14.1 0.4 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Rnk_N PF14760.6 CEG36933.1 - 0.18 12.3 0.1 0.71 10.4 0.0 2.0 2 0 0 2 2 2 0 Rnk N-terminus GrpE PF01025.19 CEG36933.1 - 0.57 9.8 3.2 1.2 8.8 3.2 1.4 1 0 0 1 1 1 0 GrpE CENP-H PF05837.12 CEG36933.1 - 1.8 9.0 5.4 1.9 8.9 2.9 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Nucleoporin_FG2 PF15967.5 CEG36933.1 - 2 6.9 85.8 0.67 8.4 35.9 3.1 1 1 1 2 2 2 0 Nucleoporin FG repeated region Fib_alpha PF08702.10 CEG36933.1 - 4.5 7.4 11.6 2.9 8.1 1.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CEG36933.1 - 7.5 7.1 7.9 12 6.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4915 PF16261.5 CEG36935.1 - 0.043 13.1 0.0 0.17 11.1 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4915) STT3 PF02516.14 CEG36936.1 - 6.2e-108 361.8 43.2 1.7e-107 360.3 43.2 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Proteasome PF00227.26 CEG36937.1 - 6.7e-64 214.9 0.3 8.7e-64 214.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEG36937.1 - 4.1e-15 55.1 0.1 1e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 CEG36938.1 - 9.5e-46 156.8 1.4 9.5e-46 156.8 1.4 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEG36938.1 - 2.5e-35 122.4 13.7 2.4e-33 115.9 4.3 3.1 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal Gpi1 PF05024.15 CEG36942.1 - 2.4e-48 164.7 13.4 4.6e-48 163.8 13.4 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) HLH PF00010.26 CEG36945.1 - 3.9e-08 33.1 0.7 9e-08 32.0 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CEG36945.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold Ribosomal_L20 PF00453.18 CEG36945.1 - 0.057 13.5 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2007 PF09413.10 CEG36945.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein UDG PF03167.19 CEG36947.1 - 1.6e-23 83.4 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ELMO_CED12 PF04727.13 CEG36948.1 - 3.1e-23 82.8 0.0 5.5e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 ELMO/CED-12 family AA_kinase PF00696.28 CEG36950.1 - 3.9e-14 52.8 0.1 5.5e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 CEG36950.1 - 1.8e-08 34.7 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEG36950.1 - 1.6e-07 31.6 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEG36950.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CEG36950.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EGF_2 PF07974.13 CEG36951.1 - 6.3e-12 45.7 49.1 5.7e-05 23.4 3.2 6.0 6 0 0 6 6 6 4 EGF-like domain EGF PF00008.27 CEG36951.1 - 2.2e-05 24.6 37.0 0.28 11.5 7.3 5.0 4 0 0 4 4 4 4 EGF-like domain FlgD_ig PF13860.6 CEG36951.1 - 0.024 14.5 0.3 4.2 7.3 0.0 3.7 3 1 0 3 3 3 0 FlgD Ig-like domain Laminin_EGF PF00053.24 CEG36951.1 - 2.1 8.6 36.5 1.9 8.7 6.7 3.8 3 0 0 3 3 3 0 Laminin EGF domain Big_8 PF17961.1 CEG36951.1 - 2.4 8.3 5.6 3 8.0 0.0 3.7 6 0 0 6 6 6 0 Bacterial Ig domain zf-DNL PF05180.12 CEG36952.1 - 1e-29 102.2 1.2 1.3e-29 101.9 0.1 1.7 2 0 0 2 2 2 1 DNL zinc finger zf-C2H2_6 PF13912.6 CEG36953.1 - 4.5e-07 29.7 0.5 3.5e-06 26.9 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG36953.1 - 8e-05 22.9 4.8 0.00097 19.5 0.3 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEG36953.1 - 0.0025 18.1 2.1 0.81 10.1 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEG36953.1 - 0.0026 18.5 0.3 0.0026 18.5 0.3 3.3 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CEG36953.1 - 0.016 15.1 1.6 0.46 10.4 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zf_RING PF16744.5 CEG36953.1 - 0.026 14.6 0.1 0.11 12.6 0.1 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger zf-met PF12874.7 CEG36953.1 - 0.04 14.3 1.9 4.7 7.8 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEG36953.1 - 0.059 13.7 1.5 3.5 8.0 0.2 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CEG36953.1 - 0.16 12.7 1.7 7.1 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 CEG36953.1 - 0.17 12.2 1.0 0.49 10.7 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S19 PF00203.21 CEG36953.1 - 0.18 11.7 1.2 0.32 10.9 0.0 2.1 2 1 0 2 2 1 0 Ribosomal protein S19 DUF5518 PF17647.1 CEG36953.1 - 0.21 11.7 0.0 0.34 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5518) Rad50_zn_hook PF04423.14 CEG36953.1 - 0.53 10.2 0.0 0.53 10.2 0.0 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-GRF PF06839.12 CEG36953.1 - 0.67 10.1 3.0 6.1 7.0 0.1 2.4 2 0 0 2 2 2 0 GRF zinc finger Methyltransf_11 PF08241.12 CEG36956.1 - 7.5e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG36956.1 - 5.1e-11 43.1 0.0 9.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG36956.1 - 2.7e-09 37.1 0.0 8.5e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG36956.1 - 3.3e-09 37.4 0.6 6.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG36956.1 - 5.8e-08 32.7 0.3 1.6e-06 28.0 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG36956.1 - 2.6e-06 26.9 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family IZUMO PF15005.6 CEG36960.1 - 0.041 14.4 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated WD40 PF00400.32 CEG36962.1 - 4.7e-47 157.0 19.6 1.7e-08 35.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG36962.1 - 2e-10 40.8 2.4 0.15 12.4 0.0 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG36962.1 - 5.8e-05 21.9 6.4 0.39 9.3 0.0 4.6 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG36962.1 - 0.00028 20.0 0.1 10 5.0 0.0 4.2 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CEG36962.1 - 0.009 14.6 0.2 0.3 9.6 0.2 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 CEG36962.1 - 0.014 14.7 0.0 5.1 6.3 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain ubiquitin PF00240.23 CEG36963.1 - 4.9e-33 112.7 0.3 7.9e-33 112.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CEG36963.1 - 1.1e-27 95.6 11.0 1.8e-27 95.0 11.0 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CEG36963.1 - 5.4e-15 55.0 0.5 8.4e-15 54.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEG36963.1 - 9.8e-05 22.7 0.1 0.00036 20.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEG36963.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEG36963.1 - 0.034 14.5 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEG36963.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEG36963.1 - 0.07 13.7 0.1 0.098 13.2 0.1 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MFP2b PF12150.8 CEG36965.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 0 Cytosolic motility protein COX6B PF02297.17 CEG36965.1 - 0.018 15.2 0.8 0.024 14.9 0.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 CEG36965.1 - 0.06 13.7 0.2 11 6.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mt_ATP-synt_D PF05873.12 CEG36966.1 - 9.9e-15 54.7 0.9 1.4e-14 54.3 0.9 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) UTP15_C PF09384.10 CEG36966.1 - 0.0016 18.1 0.1 0.0038 16.9 0.1 1.6 1 0 0 1 1 1 1 UTP15 C terminal Hrs_helical PF12210.8 CEG36966.1 - 0.013 16.0 2.9 2.8 8.5 0.1 2.7 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ApoLp-III PF07464.11 CEG36966.1 - 0.023 14.8 0.7 0.17 12.0 1.4 2.1 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ThiS PF02597.20 CEG36966.1 - 0.026 15.2 1.3 11 6.8 0.1 2.9 3 1 1 4 4 4 0 ThiS family Syntaxin-6_N PF09177.11 CEG36966.1 - 0.49 11.0 5.4 0.42 11.2 3.0 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.6 CEG36966.1 - 0.64 10.3 5.1 0.5 10.7 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HIG_1_N PF04588.13 CEG36967.1 - 1.6e-10 41.0 4.8 2.1e-10 40.7 4.8 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Syntaxin PF00804.25 CEG36968.1 - 2.2e-07 30.8 13.0 0.0014 18.4 6.7 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin-6_N PF09177.11 CEG36968.1 - 0.0083 16.7 1.9 0.019 15.5 1.9 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Phasin PF05597.11 CEG36968.1 - 0.014 15.4 1.2 0.25 11.4 0.4 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 CEG36968.1 - 0.035 14.1 1.8 0.035 14.1 1.8 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep3 PF16846.5 CEG36968.1 - 0.042 12.3 0.9 0.052 12.0 0.9 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B DUF4745 PF15923.5 CEG36968.1 - 0.064 13.2 2.2 2.2 8.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4745) Spectrin PF00435.21 CEG36968.1 - 0.58 10.7 6.3 1.9 9.0 0.4 3.0 2 1 1 3 3 3 0 Spectrin repeat PMC2NT PF08066.12 CEG36968.1 - 0.95 10.2 4.2 2.6 8.8 1.1 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Corona_S2 PF01601.16 CEG36968.1 - 1 7.8 6.8 0.22 9.9 2.5 1.8 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Baculo_p24 PF05073.12 CEG36968.1 - 1.5 8.6 7.2 1.1 9.0 4.5 2.0 2 1 0 2 2 2 0 Baculovirus P24 capsid protein PAS PF00989.25 CEG36971.1 - 5.7e-183 596.5 5.9 5.1e-20 71.6 0.0 10.3 10 0 0 10 10 10 10 PAS fold PAS_4 PF08448.10 CEG36971.1 - 2.8e-106 349.4 0.0 3.3e-12 46.6 0.0 10.5 10 0 0 10 10 10 10 PAS fold PAS_9 PF13426.7 CEG36971.1 - 9e-100 327.9 16.7 2e-10 40.8 0.0 10.6 11 0 0 11 11 11 10 PAS domain PAS_3 PF08447.12 CEG36971.1 - 3.7e-53 177.8 0.0 4.7e-07 30.0 0.1 10.3 10 0 0 10 10 10 9 PAS fold PAS_8 PF13188.7 CEG36971.1 - 1.1e-28 98.8 4.2 0.1 12.6 0.0 10.5 10 0 0 10 10 10 8 PAS domain HATPase_c PF02518.26 CEG36971.1 - 7e-27 94.2 0.0 2.4e-26 92.4 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 CEG36971.1 - 7.8e-24 84.3 3.1 0.014 16.0 0.0 9.4 10 0 0 10 10 10 5 PAS domain Response_reg PF00072.24 CEG36971.1 - 4.2e-22 78.4 0.0 1.7e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CEG36971.1 - 2.6e-17 62.6 0.3 1.2e-16 60.5 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 CEG36971.1 - 8.5e-12 45.3 13.2 0.13 12.5 0.0 10.9 10 5 0 10 10 10 3 PAS fold Hpt PF01627.23 CEG36971.1 - 2.3e-07 31.0 0.5 6.5e-07 29.5 0.5 1.8 1 0 0 1 1 1 1 Hpt domain HlyD PF00529.20 CEG36971.1 - 3.1e-05 23.8 2.1 13 5.8 0.0 5.7 6 0 0 6 6 6 1 HlyD membrane-fusion protein of T1SS GP79 PF17463.2 CEG36971.1 - 0.13 12.3 1.1 87 3.2 0.0 4.0 3 0 0 3 3 3 0 Gene product 79 sCache_3_3 PF17202.4 CEG36971.1 - 1.5 9.3 7.0 54 4.3 0.0 5.9 7 0 0 7 7 7 0 Single cache domain 3 Arm PF00514.23 CEG36972.1 - 6.1e-179 575.5 221.3 9.2e-10 38.2 0.0 70.9 76 1 0 76 76 74 45 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 CEG36972.1 - 3.4e-50 170.9 0.0 7.4e-50 169.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Arm_2 PF04826.13 CEG36972.1 - 5.3e-39 134.2 62.5 0.0025 17.3 1.3 21.4 10 4 11 21 21 21 15 Armadillo-like Pkinase_Tyr PF07714.17 CEG36972.1 - 8e-32 110.5 0.0 2.4e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CEG36972.1 - 4.7e-29 100.6 110.9 0.024 15.0 0.2 30.3 18 9 18 39 39 39 14 HEAT repeats V-ATPase_H_N PF03224.14 CEG36972.1 - 3.5e-14 52.8 31.8 0.015 14.6 0.0 16.0 10 6 3 15 15 15 4 V-ATPase subunit H KAP PF05804.12 CEG36972.1 - 3.7e-13 48.6 30.5 0.0016 16.7 1.4 11.4 7 6 3 12 12 12 5 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 CEG36972.1 - 1.4e-11 44.6 118.4 0.02 15.4 0.2 30.1 31 2 1 32 32 31 5 HEAT-like repeat RICTOR_V PF14668.6 CEG36972.1 - 7.9e-09 35.6 16.1 0.00062 19.9 0.0 11.3 13 0 0 13 13 12 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF383 PF04063.14 CEG36972.1 - 4.3e-06 26.5 30.8 0.077 12.7 1.5 10.9 10 1 0 10 10 10 4 Domain of unknown function (DUF383) Vac14_Fab1_bd PF12755.7 CEG36972.1 - 2.6e-05 24.7 15.2 19 5.9 0.0 12.2 14 1 1 15 15 12 0 Vacuolar 14 Fab1-binding region Pkinase_fungal PF17667.1 CEG36972.1 - 0.006 15.4 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEG36972.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HEAT PF02985.22 CEG36972.1 - 0.086 13.1 0.1 0.086 13.1 0.1 33.1 43 0 0 43 43 39 0 HEAT repeat Seadorna_VP7 PF07387.11 CEG36972.1 - 0.1 11.6 0.1 0.26 10.3 0.1 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Nipped-B_C PF12830.7 CEG36972.1 - 2.4 8.1 6.5 12 5.8 0.0 5.2 6 0 0 6 6 6 0 Sister chromatid cohesion C-terminus PRELI PF04707.14 CEG36973.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family ACBP PF00887.19 CEG36973.1 - 7.1e-07 29.4 0.1 1.5e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein COX1 PF00115.20 CEG36973.1 - 0.071 11.9 0.2 0.094 11.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I ERM PF00769.19 CEG36975.1 - 0.0092 15.8 7.9 0.012 15.5 7.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 CEG36975.1 - 0.022 12.7 2.3 0.024 12.6 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FPP PF05911.11 CEG36975.1 - 0.036 12.3 8.4 0.051 11.8 8.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 CEG36975.1 - 1.1 9.8 20.1 0.34 11.4 12.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CEG36975.1 - 3.1 7.8 13.2 7.5 6.6 12.6 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 CEG36975.1 - 6.4 7.5 11.5 2 9.1 4.0 2.8 1 1 1 2 2 2 0 SlyX Spc24 PF08286.11 CEG36975.1 - 8.4 6.7 7.9 6.7 7.0 3.4 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4509 PF14970.6 CEG36976.1 - 2.8e-10 40.4 1.3 2.8e-10 40.4 1.3 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4509) DUF2730 PF10805.8 CEG36976.1 - 0.053 13.6 0.2 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) PARG_cat PF05028.14 CEG36976.1 - 0.28 10.4 6.5 0.22 10.8 4.3 1.7 1 1 1 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) Syntaxin_2 PF14523.6 CEG36976.1 - 0.59 10.5 7.6 4.6 7.7 1.4 3.4 2 2 1 3 3 3 0 Syntaxin-like protein BLOC1_2 PF10046.9 CEG36976.1 - 1.2 9.4 5.9 8.7 6.7 0.0 3.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 CEG36976.1 - 3.2 7.9 7.5 0.57 10.3 0.2 2.9 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase LPP PF04728.13 CEG36976.1 - 4.9 7.6 7.7 8.9 6.8 0.8 3.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Pyr_redox_2 PF07992.14 CEG36977.1 - 1.1e-40 139.7 0.0 1.7e-40 139.1 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEG36977.1 - 0.001 19.6 0.1 0.0077 16.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEG36977.1 - 0.017 15.1 0.0 0.72 9.8 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 CEG36977.1 - 0.098 12.2 0.0 59 3.1 0.0 3.1 1 1 2 4 4 4 0 FAD dependent oxidoreductase Peptidase_M22 PF00814.25 CEG36978.1 - 4.7e-87 292.1 0.0 8.2e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family U3snoRNP10 PF12397.8 CEG36978.1 - 0.75 10.2 4.8 2.2 8.7 0.5 3.5 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 MFS_1 PF07690.16 CEG36980.1 - 1.6e-13 50.4 21.5 1.6e-13 50.4 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG36980.1 - 0.00033 19.7 21.2 0.00071 18.6 21.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter ThiC_Rad_SAM PF01964.18 CEG36980.1 - 0.27 10.0 0.4 0.38 9.5 0.4 1.1 1 0 0 1 1 1 0 Radical SAM ThiC family Sacchrp_dh_C PF16653.5 CEG36984.1 - 2.1e-84 283.8 0.0 3.1e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 CEG36984.1 - 1.1e-27 97.0 0.0 2.1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 CEG36984.1 - 1.2e-16 61.2 0.0 3.4e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 CEG36984.1 - 2e-09 37.8 0.0 5.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 CEG36984.1 - 6.4e-05 22.3 0.0 0.18 11.1 0.0 3.4 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAM212 PF15342.6 CEG36991.1 - 0.016 15.0 0.5 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 FAM212 family Pkinase PF00069.25 CEG36993.1 - 5.6e-52 176.7 0.0 8.8e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG36993.1 - 8.3e-49 166.2 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG36993.1 - 0.00021 20.2 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 CEG36993.1 - 0.079 13.1 0.0 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 ABC1 family DUF4690 PF15756.5 CEG36993.1 - 0.12 13.0 3.6 0.14 12.8 2.1 1.8 1 1 0 1 1 1 0 Small Novel Rich in Cartilage FTCD_C PF04961.12 CEG36993.1 - 0.14 11.9 0.3 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Haspin_kinase PF12330.8 CEG36993.1 - 0.17 10.8 0.0 0.38 9.6 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Amnionless PF14828.6 CEG36993.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Sugar_tr PF00083.24 CEG36994.1 - 5.3e-35 121.1 19.5 8.1e-35 120.6 19.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG36994.1 - 7e-25 87.7 54.4 3.1e-22 79.0 29.0 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily GGACT PF06094.12 CEG36995.1 - 0.09 13.4 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like LRR_1 PF00560.33 CEG36996.1 - 0.057 14.0 4.4 7.5 7.5 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 CEG36996.1 - 0.06 13.8 12.3 1.3 9.5 0.6 4.9 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG36996.1 - 0.066 13.0 7.7 2.5 7.9 0.1 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_12 PF18837.1 CEG36996.1 - 0.25 11.0 1.3 0.86 9.3 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat F-box PF00646.33 CEG36996.1 - 4.2 7.4 6.5 9.8 6.2 0.0 2.9 3 0 0 3 3 3 0 F-box domain IQ PF00612.27 CEG36997.1 - 0.00078 19.0 1.0 0.0027 17.3 0.3 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif ARL2_Bind_BART PF11527.8 CEG36998.1 - 3.1e-20 72.4 5.7 4.4e-20 71.9 5.7 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART EB1 PF03271.17 CEG36999.1 - 2.8e-16 59.5 0.2 6.9e-16 58.2 0.2 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CEG36999.1 - 3.2e-09 36.9 1.0 4.3e-09 36.5 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 CEG36999.1 - 0.0015 18.6 0.1 0.0024 17.9 0.1 1.3 1 0 0 1 1 1 1 CH-like domain in sperm protein APG6_N PF17675.1 CEG36999.1 - 0.014 16.0 1.7 0.024 15.2 1.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 CEG36999.1 - 0.02 15.0 0.5 0.044 13.9 0.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.8 CEG36999.1 - 0.14 12.2 2.7 0.24 11.4 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 CEG36999.1 - 0.4 11.2 4.3 0.21 12.0 2.1 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Med3 PF11593.8 CEG36999.1 - 7 5.7 9.8 12 5.0 9.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AMPK1_CBM PF16561.5 CEG37001.1 - 1.3e-32 111.8 0.5 2.4e-32 111.0 0.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CEG37001.1 - 8.1e-19 67.7 0.5 1.8e-18 66.5 0.5 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 CEG37001.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ost5 PF05251.12 CEG37002.1 - 6.6e-20 71.1 4.3 7.3e-20 71.0 4.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 YlaH PF14036.6 CEG37002.1 - 0.045 14.1 1.7 0.055 13.8 1.7 1.1 1 0 0 1 1 1 0 YlaH-like protein CbtB PF09489.10 CEG37002.1 - 0.065 13.3 5.0 0.12 12.4 0.7 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF5392 PF17370.2 CEG37002.1 - 0.12 12.5 0.9 0.13 12.3 0.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5392) GNVR PF13807.6 CEG37002.1 - 0.18 11.8 1.9 5.7 6.9 0.4 2.0 1 1 1 2 2 2 0 G-rich domain on putative tyrosine kinase SSPI PF14098.6 CEG37002.1 - 0.26 11.5 1.3 4.3 7.6 0.5 2.0 2 0 0 2 2 2 0 Small, acid-soluble spore protein I DUF2721 PF11026.8 CEG37002.1 - 0.3 11.0 5.9 0.37 10.7 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pinin_SDK_memA PF04696.13 CEG37003.1 - 5.3e-23 81.5 10.0 5.3e-23 81.5 10.0 4.2 3 1 1 4 4 4 1 pinin/SDK/memA/ protein conserved region SAP PF02037.27 CEG37003.1 - 1.1e-11 44.2 0.9 2.2e-11 43.2 0.9 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 CEG37003.1 - 0.062 13.0 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 HeH/LEM domain B9-C2 PF07162.11 CEG37004.1 - 1.2e-44 152.5 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF2183 PF09949.9 CEG37005.1 - 1.2e-05 25.5 0.0 3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) HTH_psq PF05225.16 CEG37006.1 - 3.5e-09 36.2 2.0 0.00084 19.0 0.3 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 CEG37006.1 - 0.19 11.6 1.4 18 5.3 0.5 2.5 2 0 0 2 2 2 0 Homeodomain-like domain START PF01852.19 CEG37010.1 - 4.3e-21 75.3 0.1 5.2e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 START domain PH PF00169.29 CEG37013.1 - 0.01 16.4 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_17 PF18012.1 CEG37013.1 - 0.11 12.2 0.1 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 PH domain Elicitin PF00964.17 CEG37014.1 - 1.3e-10 41.2 5.6 2.5e-10 40.3 5.6 1.5 1 0 0 1 1 1 1 Elicitin Glyco_hydro81C PF17652.1 CEG37020.1 - 1.3e-121 406.1 4.0 1.9e-121 405.6 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG37020.1 - 1.6e-44 152.4 0.3 3.1e-44 151.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Acetyltransf_10 PF13673.7 CEG37021.1 - 3.2e-05 23.9 0.0 7.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEG37021.1 - 0.00015 21.8 0.0 0.00036 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG37021.1 - 0.0014 18.8 0.0 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEG37021.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG37021.1 - 0.0025 17.8 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Ipi1_N PF12333.8 CEG37023.1 - 5.4e-10 39.8 4.0 3.6e-09 37.1 0.1 3.8 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 CEG37023.1 - 0.0034 17.5 0.6 0.21 11.9 0.1 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CEG37023.1 - 0.065 13.6 0.9 0.23 11.9 0.3 2.4 2 0 0 2 2 2 0 HEAT repeats MBOAT_2 PF13813.6 CEG37023.1 - 0.75 10.1 2.5 1.7 9.0 0.0 2.9 4 0 0 4 4 4 0 Membrane bound O-acyl transferase family PP2C PF00481.21 CEG37025.1 - 4.9e-50 170.6 1.3 3.5e-45 154.7 0.1 3.0 2 1 1 3 3 3 2 Protein phosphatase 2C GHMP_kinases_C PF08544.13 CEG37025.1 - 6e-06 26.5 0.0 2.3e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal FlxA PF14282.6 CEG37025.1 - 0.013 15.4 6.5 0.013 15.4 6.5 2.1 2 0 0 2 2 2 0 FlxA-like protein NAS PF03059.16 CEG37025.1 - 0.036 13.4 0.4 0.057 12.7 0.4 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein RACo_linker PF17650.1 CEG37025.1 - 0.042 13.7 0.3 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 RACo linker region Tachystatin_A PF11406.8 CEG37025.1 - 0.092 12.8 0.5 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Antimicrobial peptide tachystatin A GHMP_kinases_N PF00288.26 CEG37026.1 - 6.1e-17 61.6 0.3 9.3e-16 57.8 0.2 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF667 PF05018.13 CEG37027.1 - 1.6e-27 96.4 0.0 3.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) zf-UBR PF02207.20 CEG37028.1 - 9.3e-17 61.0 14.0 9.3e-17 61.0 14.0 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CEG37028.1 - 3.3e-08 33.2 0.0 1.2e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Dimerisation PF08100.11 CEG37028.1 - 0.18 11.9 0.3 17 5.5 0.1 3.4 3 0 0 3 3 3 0 Dimerisation domain Dzip-like_N PF13815.6 CEG37029.1 - 1.4e-07 31.5 1.4 1.2e-06 28.5 0.5 2.4 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Collagen_bind_2 PF12904.7 CEG37029.1 - 0.065 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Lipase_GDSL_3 PF14606.6 CEG37030.1 - 0.11 12.6 1.5 0.19 11.9 0.9 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Na_H_Exchanger PF00999.21 CEG37031.1 - 1.2e-49 169.1 40.1 1.5e-49 168.9 40.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SP_C-Propep PF08999.10 CEG37031.1 - 1.7 8.5 6.8 0.98 9.3 0.1 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Sulfatase PF00884.23 CEG37032.1 - 1.1e-28 100.6 0.3 1.7e-28 99.9 0.3 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CEG37032.1 - 2.7e-06 26.3 0.2 4.8e-06 25.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CEG37032.1 - 0.00036 20.2 0.3 0.0042 16.7 0.3 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2092 PF09865.9 CEG37032.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) 4HBT_2 PF13279.6 CEG37033.1 - 1.6e-06 28.6 0.1 2.3e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Lon_C PF05362.13 CEG37038.1 - 4.5e-70 235.4 0.1 8.2e-70 234.5 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CEG37038.1 - 3.4e-36 125.1 0.9 1.2e-35 123.3 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CEG37038.1 - 2.3e-22 79.8 0.0 8.9e-22 77.9 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) 4HBT_2 PF13279.6 CEG37038.1 - 2.9e-18 66.5 0.0 7.1e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase-like superfamily ChlI PF13541.6 CEG37038.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 CEG37038.1 - 1.5e-06 28.4 0.0 5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CEG37038.1 - 7.5e-05 22.5 0.0 0.00046 20.0 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 CEG37038.1 - 8.5e-05 21.6 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_5 PF07728.14 CEG37038.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG37038.1 - 0.00042 20.6 0.6 0.012 15.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG37038.1 - 0.0011 19.4 0.2 0.0062 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEG37038.1 - 0.0018 18.2 0.0 0.011 15.7 0.0 2.3 3 0 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 CEG37038.1 - 0.0071 16.9 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CEG37038.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CEG37038.1 - 0.03 13.5 1.5 0.088 12.0 0.0 2.3 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 CEG37038.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CEG37038.1 - 0.041 14.0 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase RNA_helicase PF00910.22 CEG37038.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CEG37038.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 CEG37038.1 - 0.087 13.3 0.9 0.56 10.7 0.1 2.5 2 0 0 2 2 2 0 ABC transporter Retrotran_gag_2 PF14223.6 CEG37039.1 - 1.6e-27 95.8 2.1 2.1e-27 95.5 2.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG37039.1 - 2.3e-06 27.4 1.8 4e-06 26.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle SPK PF04435.18 CEG37039.1 - 0.049 14.0 1.1 0.57 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF545) zf-CCHC_4 PF14392.6 CEG37039.1 - 0.15 11.8 3.1 0.16 11.7 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEG37039.1 - 0.48 10.3 1.6 0.82 9.5 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle BBS1 PF14779.6 CEG37042.1 - 3.6e-77 259.2 0.3 1.1e-38 133.2 0.0 2.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 CEG37042.1 - 1.4e-08 34.8 0.2 0.15 12.1 0.0 3.7 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 CEG37042.1 - 0.0088 15.4 0.1 0.064 12.6 0.1 2.3 2 1 0 3 3 3 1 PTHB1 N-terminus PPPI_inhib PF14895.6 CEG37042.1 - 0.032 13.4 0.1 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor NUP214 PF16755.5 CEG37042.1 - 0.055 12.7 0.2 0.34 10.1 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 FIST_C PF10442.9 CEG37044.1 - 1.6e-15 57.2 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 CEG37044.1 - 2.4e-15 56.9 0.7 3.2e-14 53.3 0.3 2.4 2 0 0 2 2 2 1 FIST N domain FYVE PF01363.21 CEG37044.1 - 3.7e-14 52.6 13.5 7.7e-14 51.6 13.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG37044.1 - 0.74 10.0 8.0 1.9 8.7 8.0 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 CEG37044.1 - 2.4 8.5 8.6 0.37 11.0 3.9 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 CEG37044.1 - 8.3 6.7 9.4 3.1 8.0 3.8 2.5 2 0 0 2 2 2 0 B-box zinc finger DEAD PF00270.29 CEG37045.1 - 1.1e-49 168.6 0.0 2.4e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG37045.1 - 1.5e-25 89.7 0.0 5.6e-25 87.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain QRPTase_C PF01729.19 CEG37045.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain SUZ PF12752.7 CEG37047.1 - 9.6 7.1 6.6 4.6 8.1 0.2 2.7 2 0 0 2 2 2 0 SUZ domain SQS_PSY PF00494.19 CEG37048.1 - 1.2e-50 172.4 1.0 1.6e-50 172.1 1.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PikAIV_N PF18605.1 CEG37050.1 - 4.1 7.1 11.6 1.9 8.2 0.3 3.6 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain GDI PF00996.18 CEG37051.1 - 0.13 10.7 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor CDC37_N PF03234.14 CEG37051.1 - 1.9 9.4 6.2 0.88 10.5 1.4 2.3 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Adaptin_N PF01602.20 CEG37053.1 - 2.5e-102 343.1 0.0 3.5e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CEG37053.1 - 1.2e-14 54.5 1.0 2.4e-14 53.6 1.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 CEG37053.1 - 1.6e-11 44.4 0.0 3.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 CEG37053.1 - 9e-06 25.8 0.1 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Coatamer_beta_C PF07718.12 CEG37053.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Coatomer beta C-terminal region Kinesin PF00225.23 CEG37054.1 - 4.8e-81 272.3 0.1 2.3e-40 138.5 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CEG37054.1 - 2.4e-27 95.7 1.0 2.9e-26 92.2 0.1 2.6 2 0 0 2 2 2 1 Microtubule binding Filament PF00038.21 CEG37054.1 - 3.5e-05 23.6 5.8 3.5e-05 23.6 5.8 2.8 4 0 0 4 4 4 1 Intermediate filament protein RILP PF11461.8 CEG37054.1 - 0.082 13.1 0.4 0.41 10.9 0.4 2.3 1 0 0 1 1 1 0 Rab interacting lysosomal protein Mt_ATP-synt_D PF05873.12 CEG37054.1 - 0.22 11.4 8.4 0.99 9.2 0.4 2.9 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4510 PF14971.6 CEG37054.1 - 0.31 11.4 0.1 0.31 11.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) Prefoldin PF02996.17 CEG37054.1 - 1.4 8.9 15.0 1.5 8.8 1.0 3.2 4 0 0 4 4 4 0 Prefoldin subunit DUF4140 PF13600.6 CEG37054.1 - 3.3 8.2 5.9 4.4 7.8 0.5 3.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PKcGMP_CC PF16808.5 CEG37054.1 - 3.4 7.6 9.9 8.7 6.3 0.2 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lzipper-MIP1 PF14389.6 CEG37054.1 - 5.2 7.4 10.2 16 5.9 0.0 4.1 4 0 0 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 WD40_alt PF14077.6 CEG37054.1 - 9.5 6.2 9.3 1.9 8.4 0.0 3.6 4 0 0 4 4 4 0 Alternative WD40 repeat motif Macro PF01661.21 CEG37058.1 - 4.4e-30 104.1 0.4 1.7e-29 102.2 0.1 1.8 1 1 1 2 2 2 1 Macro domain Macro_2 PF14519.6 CEG37058.1 - 0.021 14.2 0.3 0.1 11.9 0.0 2.2 2 1 0 2 2 2 0 Macro-like domain HEAT_2 PF13646.6 CEG37059.1 - 0.0014 19.0 0.1 0.032 14.6 0.0 3.0 4 0 0 4 4 4 1 HEAT repeats Peptidase_M1_N PF17900.1 CEG37059.1 - 0.0017 18.6 0.0 2.1 8.5 0.0 2.3 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CEG37059.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF4203 PF13886.6 CEG37062.1 - 6.8e-49 166.3 30.0 8.6e-49 165.9 30.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CPP1-like PF11833.8 CEG37062.1 - 2.4 7.8 15.1 2.8 7.6 4.4 2.8 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DPM2 PF07297.12 CEG37062.1 - 3.2 8.1 9.2 0.41 11.0 0.6 3.1 1 1 2 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Rax2 PF12768.7 CEG37062.1 - 3.5 7.0 5.2 2.5 7.5 0.8 2.4 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Ysc84 PF04366.12 CEG37064.1 - 1e-33 115.8 0.1 2.1e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator zf-C2HC5 PF06221.13 CEG37064.1 - 0.0035 17.3 2.4 0.099 12.6 0.6 2.4 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.6 CEG37064.1 - 0.064 13.2 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 CEG37064.1 - 0.074 13.1 0.8 0.14 12.2 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CEG37064.1 - 0.17 11.4 2.5 0.51 9.8 2.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Aminotran_1_2 PF00155.21 CEG37066.1 - 2.4e-14 53.3 0.0 2.1e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II DHHC PF01529.20 CEG37067.1 - 2.3e-33 115.2 5.6 2.3e-33 115.2 5.6 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CEG37067.1 - 5.5e-24 84.6 3.1 1.1e-10 41.9 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG37067.1 - 5.7e-19 67.9 1.7 1.7e-08 34.5 0.2 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG37067.1 - 2.9e-14 53.2 1.0 7e-06 26.5 0.0 5.3 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG37067.1 - 2.2e-12 46.8 11.6 7.8e-05 22.9 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CEG37067.1 - 1.1e-10 40.8 0.1 0.0047 17.3 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Lyase_1 PF00206.20 CEG37070.1 - 1.9e-19 70.2 0.1 3.3e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CEG37070.1 - 1.4e-16 60.8 0.2 6.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Bromodomain PF00439.25 CEG37071.1 - 4.3e-22 78.0 0.0 8.6e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 CEG37071.1 - 1.3e-05 25.4 0.1 2.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 CEG37071.1 - 0.013 15.4 1.2 0.051 13.5 1.2 2.0 1 0 0 1 1 1 0 PHD-finger WHIM1 PF15612.6 CEG37071.1 - 0.02 14.4 0.0 0.059 12.9 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 mit_SMPDase PF14724.6 CEG37072.1 - 1.1e-15 56.7 0.0 5.6e-08 31.3 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase CorA PF01544.18 CEG37072.1 - 0.056 12.8 5.9 0.17 11.2 5.9 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2569 PF10754.9 CEG37072.1 - 0.058 13.8 1.4 0.14 12.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) BCIP PF13862.6 CEG37076.1 - 0.093 12.5 0.1 0.12 12.2 0.1 1.3 1 1 0 1 1 1 0 p21-C-terminal region-binding protein FYVE PF01363.21 CEG37078.1 - 0.0038 17.3 6.5 0.014 15.5 6.5 2.0 1 0 0 1 1 1 1 FYVE zinc finger Vps39_2 PF10367.9 CEG37078.1 - 0.024 15.1 1.5 0.081 13.4 1.5 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Peptidase_S49 PF01343.18 CEG37078.1 - 0.033 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 PSCyt3 PF07627.11 CEG37078.1 - 0.072 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) FYVE_2 PF02318.16 CEG37078.1 - 0.82 9.9 9.3 0.51 10.6 7.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Rootletin PF15035.6 CEG37080.1 - 0.076 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FYVE PF01363.21 CEG37081.1 - 0.52 10.5 8.7 1.3 9.2 8.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG37081.1 - 1.5 9.0 12.8 0.17 12.1 7.8 2.0 2 1 1 3 3 3 0 FYVE-type zinc finger C6_DPF PF10170.9 CEG37081.1 - 6 7.3 11.4 2e+02 2.4 11.4 3.0 2 1 0 2 2 2 0 Cysteine-rich domain FYVE_2 PF02318.16 CEG37084.1 - 0.48 10.7 7.6 0.94 9.7 7.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG37084.1 - 3 8.1 10.3 5.9 7.1 10.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE PF01363.21 CEG37085.1 - 0.006 16.7 9.2 0.012 15.8 9.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-CHY PF05495.12 CEG37085.1 - 0.93 10.0 7.2 2 8.9 7.2 1.6 1 0 0 1 1 1 0 CHY zinc finger zf_Rg PF17915.1 CEG37085.1 - 2.2 7.7 6.8 7.1 6.1 6.7 1.9 1 1 0 1 1 1 0 Reverse gyrase zinc finger FYVE_2 PF02318.16 CEG37086.1 - 0.034 14.4 7.6 0.087 13.0 7.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Cupin_8 PF13621.6 CEG37087.1 - 6e-69 232.6 0.9 7.8e-69 232.2 0.9 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEG37087.1 - 0.00052 19.6 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CEG37087.1 - 0.035 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase PUL PF08324.11 CEG37091.1 - 4.8e-40 137.5 1.7 6.2e-40 137.2 1.7 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 CEG37091.1 - 1.8e-30 104.5 8.7 1.5e-06 28.8 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.11 CEG37091.1 - 1.5e-23 83.2 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Calci_bind_CcbP PF11535.8 CEG37092.1 - 0.21 12.1 1.8 0.29 11.7 1.6 1.3 1 1 0 1 1 1 0 Calcium binding Glyc_hyd_38C_2 PF18230.1 CEG37093.1 - 0.071 13.2 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain Raf1_HTH PF18579.1 CEG37094.1 - 0.028 14.1 2.6 7 6.4 0.0 4.6 5 0 0 5 5 5 0 Rubisco accumulation factor 1 helix turn helix domain RXLR PF16810.5 CEG37095.1 - 0.021 15.2 0.0 0.024 15.1 0.0 1.0 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Apo-CII PF05355.11 CEG37096.1 - 0.071 13.3 0.0 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Apolipoprotein C-II TMC PF07810.13 CEG37098.1 - 0.21 12.2 3.9 1 9.9 1.3 2.0 1 1 1 2 2 2 0 TMC domain DUF3337 PF11816.8 CEG37102.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) PCI PF01399.27 CEG37106.1 - 9.8e-11 42.1 0.1 1.6e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 PCI domain Ribosomal_L35Ae PF01247.18 CEG37107.1 - 2.3e-41 139.8 1.5 4.8e-41 138.8 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L35Ae HA2 PF04408.23 CEG37107.1 - 1.8e-21 76.4 0.1 3.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEG37107.1 - 2.6e-16 59.9 0.0 9.4e-16 58.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG37107.1 - 5.2e-09 36.1 0.2 1.4e-08 34.7 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG37107.1 - 5.4e-05 23.5 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CEG37107.1 - 0.00023 21.1 0.2 0.00066 19.7 0.2 1.7 1 1 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 CEG37107.1 - 0.00034 20.6 0.0 0.0032 17.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CEG37107.1 - 0.0016 19.0 0.1 0.12 12.9 0.1 3.2 2 1 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 CEG37107.1 - 0.002 18.5 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEG37107.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEG37107.1 - 0.021 14.9 0.0 0.85 9.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CEG37107.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 CEG37107.1 - 0.047 13.1 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CEG37107.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 CEG37107.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CEG37107.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 KaiC Ferric_reduct PF01794.19 CEG37108.1 - 2.7e-19 69.5 6.0 2.7e-19 69.5 6.0 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CEG37108.1 - 9.6e-13 48.2 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CEG37108.1 - 1.2e-08 35.2 0.0 9.3e-08 32.3 0.0 2.2 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CEG37108.1 - 0.0071 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SVM_signal PF12113.8 CEG37108.1 - 5 7.1 12.5 0.21 11.5 6.1 2.1 2 0 0 2 2 2 0 SVM protein signal sequence CbiX PF01903.17 CEG37110.1 - 3.3e-05 24.2 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 2 CbiX ADSL_C PF10397.9 CEG37111.1 - 1.3 9.6 4.2 58 4.3 0.1 4.6 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus GAS PF13851.6 CEG37112.1 - 0.0016 17.8 16.1 0.0086 15.4 9.3 2.4 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 CEG37112.1 - 0.077 12.8 10.1 0.14 12.0 8.6 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF1485 PF07364.12 CEG37112.1 - 0.13 11.5 0.1 0.32 10.2 0.1 1.6 1 0 0 1 1 1 0 Metallopeptidase family M81 APG6_N PF17675.1 CEG37112.1 - 1 9.9 20.5 1 9.9 13.1 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 CEG37112.1 - 1.6 8.8 19.7 1.9 8.6 10.9 2.7 3 0 0 3 3 3 0 Tropomyosin like Val_tRNA-synt_C PF10458.9 CEG37112.1 - 5.5 7.3 14.8 3.2 8.1 0.9 3.9 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Cnn_1N PF07989.11 CEG37112.1 - 6.7 6.9 11.7 6.7 7.0 4.9 3.7 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 EF-hand_1 PF00036.32 CEG37114.1 - 2.1e-10 39.4 1.2 0.00081 18.8 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG37114.1 - 7e-10 38.0 2.4 0.00013 21.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CEG37114.1 - 2.2e-08 33.2 1.1 0.0031 16.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG37114.1 - 5e-08 33.3 1.1 1.3e-07 32.0 0.5 2.0 2 0 0 2 2 2 1 EF-hand domain pair MIP-T3 PF10243.9 CEG37114.1 - 1.5e-07 31.3 0.1 4.4e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain EF-hand_8 PF13833.6 CEG37114.1 - 1.6e-05 24.6 1.3 0.00011 22.0 0.4 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 CEG37114.1 - 0.028 14.3 1.6 0.2 11.5 0.6 2.7 1 1 1 2 2 2 0 EF hand DUF2624 PF11116.8 CEG37114.1 - 0.062 14.2 0.5 0.71 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) DUF2201_N PF13203.6 CEG37114.1 - 0.32 10.5 4.6 7.9 6.0 0.6 2.8 2 1 1 3 3 3 0 Putative metallopeptidase domain SNF2_N PF00176.23 CEG37115.1 - 8.5e-61 205.6 0.2 1.4e-59 201.6 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-HC5HC2H_2 PF13832.6 CEG37115.1 - 4.3e-21 75.1 13.3 1.8e-20 73.1 6.5 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain Helicase_C PF00271.31 CEG37115.1 - 5.7e-19 68.5 0.0 1.5e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 CEG37115.1 - 9.2e-17 61.1 15.2 1.1e-16 60.9 4.3 2.9 2 1 0 2 2 2 1 PHD-like zinc-binding domain Chromo PF00385.24 CEG37115.1 - 1.6e-16 60.0 5.9 2.8e-08 33.6 3.4 3.3 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.6 CEG37115.1 - 1.6e-11 43.5 2.4 1.6e-11 43.5 2.4 2.7 3 0 0 3 3 3 1 PHD-finger ResIII PF04851.15 CEG37115.1 - 5.8e-09 36.2 7.8 6.1e-09 36.1 0.0 3.7 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit PHD PF00628.29 CEG37115.1 - 8.6e-09 35.2 17.9 1.8e-08 34.2 6.3 2.8 2 0 0 2 2 2 1 PHD-finger HDA2-3 PF11496.8 CEG37115.1 - 7.2e-06 25.4 0.0 2.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 QLQ PF08880.11 CEG37115.1 - 5.6e-05 22.8 1.5 7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 QLQ PDZ_2 PF13180.6 CEG37115.1 - 0.00061 20.1 0.0 0.024 15.0 0.0 2.8 2 0 0 2 2 2 1 PDZ domain FYVE_2 PF02318.16 CEG37115.1 - 0.0063 16.7 1.0 0.0063 16.7 1.0 3.0 2 0 0 2 2 2 1 FYVE-type zinc finger DEAD PF00270.29 CEG37115.1 - 0.0085 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HemolysinCabind PF00353.19 CEG37115.1 - 0.015 15.3 1.4 0.034 14.1 1.4 1.5 1 0 0 1 1 1 0 RTX calcium-binding nonapeptide repeat (4 copies) PDZ PF00595.24 CEG37115.1 - 0.079 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 PDZ domain AT_hook PF02178.19 CEG37115.1 - 0.16 12.0 3.9 0.69 10.0 3.9 2.2 1 0 0 1 1 1 0 AT hook motif TFIIF_beta PF02270.15 CEG37117.1 - 3.2e-21 75.2 0.3 5.6e-21 74.4 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CEG37117.1 - 2.3e-07 31.5 0.8 6.6e-07 30.1 0.8 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus REC1 PF18501.1 CEG37117.1 - 0.038 13.9 2.1 0.23 11.3 1.9 1.9 1 1 1 2 2 2 0 Alpha helical recognition lobe domain HEM4 PF02602.15 CEG37118.1 - 3.7e-22 78.8 0.0 4.9e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Serglycin PF04360.12 CEG37126.1 - 0.029 14.3 0.5 0.034 14.1 0.5 1.1 1 0 0 1 1 1 0 Serglycin IQ PF00612.27 CEG37127.1 - 0.0015 18.1 36.5 0.0095 15.7 0.1 5.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Ecm29 PF13001.7 CEG37129.1 - 4.3e-45 154.3 17.4 1.1e-43 149.7 9.5 3.7 4 0 0 4 4 4 2 Proteasome stabiliser dCMP_cyt_deam_1 PF00383.23 CEG37129.1 - 1.5e-21 76.1 1.8 5.1e-21 74.5 1.8 2.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEG37129.1 - 1.7e-18 66.7 0.3 4.1e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 CEG37129.1 - 0.00032 20.8 0.9 0.0027 17.8 0.1 2.5 2 0 0 2 2 2 1 APOBEC3 SNAD4 PF18750.1 CEG37129.1 - 0.0024 18.0 0.2 0.0091 16.1 0.2 2.0 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 CEG37129.1 - 0.0094 16.0 0.9 0.027 14.5 0.1 2.2 2 0 0 2 2 2 1 APOBEC2 NAD1 PF18778.1 CEG37129.1 - 0.023 14.8 0.2 0.18 11.9 0.1 2.3 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CEG37129.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase NAD2 PF18782.1 CEG37129.1 - 0.12 12.4 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 HU-CCDC81_euk_1 PF14908.6 CEG37129.1 - 0.13 12.5 0.1 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 CCDC81 eukaryotic HU domain 1 HEAT PF02985.22 CEG37129.1 - 0.92 9.9 31.6 4.5 7.8 0.4 8.9 9 0 0 9 9 8 0 HEAT repeat GGACT PF06094.12 CEG37131.1 - 3.2e-18 66.5 0.1 4.3e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CEG37131.1 - 2.9e-05 24.4 0.1 4.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family DUF659 PF04937.15 CEG37133.1 - 2.4e-12 47.0 0.1 5.1e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CEG37133.1 - 0.0011 18.7 0.0 0.0038 17.0 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CEG37133.1 - 0.0034 17.4 1.3 0.005 16.8 0.1 2.0 2 0 0 2 2 2 1 BED zinc finger DUF3668 PF12416.8 CEG37134.1 - 7e-19 68.5 0.1 1.9e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 Cep120 protein UPF0227 PF05728.12 CEG37134.1 - 1.3 8.9 6.9 0.07 13.1 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ribosomal_S17_N PF16205.5 CEG37137.1 - 1.7e-31 108.4 2.1 1.7e-31 108.4 2.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CEG37137.1 - 1.7e-26 92.1 1.2 1.7e-26 92.1 1.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Mg_trans_NIPA PF05653.14 CEG37138.1 - 5.5e-28 97.9 9.6 1.5e-19 70.3 0.8 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA UbiA PF01040.18 CEG37138.1 - 0.00074 18.9 1.3 0.00074 18.9 1.3 2.2 2 1 0 2 2 2 1 UbiA prenyltransferase family CytochromB561_N PF09786.9 CEG37138.1 - 0.0022 17.1 0.3 0.0063 15.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome B561, N terminal Multi_Drug_Res PF00893.19 CEG37138.1 - 0.018 15.7 7.4 0.066 13.9 0.5 3.1 2 2 0 2 2 2 0 Small Multidrug Resistance protein DUF3098 PF11297.8 CEG37138.1 - 0.073 12.7 0.3 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) EamA PF00892.20 CEG37138.1 - 0.35 11.0 12.9 0.064 13.4 2.2 3.1 3 0 0 3 3 3 0 EamA-like transporter family His_Phos_2 PF00328.22 CEG37143.1 - 1.2e-20 74.2 0.2 1.7e-18 67.1 0.2 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Kinesin PF00225.23 CEG37144.1 - 7.6e-96 320.9 1.9 7.6e-96 320.9 1.9 2.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEG37144.1 - 5.5e-28 97.8 12.6 1e-27 96.9 0.0 4.8 4 1 1 5 5 5 2 Microtubule binding Fez1 PF06818.15 CEG37144.1 - 0.45 10.9 112.1 0.052 14.0 20.9 5.7 2 1 3 5 5 5 0 Fez1 Halo_GVPC PF05465.13 CEG37144.1 - 4.9 7.5 9.4 5.7 7.3 0.0 4.2 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat OSTMP1 PF09777.9 CEG37146.1 - 0.0015 17.9 0.3 0.0028 17.1 0.0 1.5 2 0 0 2 2 2 1 Osteopetrosis-associated transmembrane protein 1 precursor Hydrolase_4 PF12146.8 CEG37146.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 YojJ PF10372.9 CEG37150.1 - 0.41 10.8 11.1 1.9 8.6 0.0 5.0 3 2 2 5 5 5 0 Bacterial membrane-spanning protein N-terminus LsmAD PF06741.13 CEG37151.1 - 2.1e-24 85.8 3.4 2.1e-24 85.8 3.4 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CEG37151.1 - 4.4e-11 42.8 0.0 1.4e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 CEG37151.1 - 0.00045 19.7 5.3 0.037 13.7 0.5 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Abhydro_lipase PF04083.16 CEG37152.1 - 2.2e-19 68.8 0.0 5.4e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEG37152.1 - 1.1e-13 51.5 1.6 1.7e-13 50.8 1.6 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG37152.1 - 0.0064 15.8 0.1 0.0094 15.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CEG37152.1 - 0.12 11.2 0.5 7.5 5.4 0.1 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme rpo30_N PF12410.8 CEG37152.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit 2-Hacid_dh_C PF02826.19 CEG37153.1 - 6e-56 188.6 0.0 8.8e-56 188.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEG37153.1 - 7.3e-28 96.9 0.0 8.4e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 CEG37153.1 - 0.06 13.9 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CEG37153.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CEG37153.1 - 0.12 12.4 0.0 0.71 9.9 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M18 PF02127.15 CEG37156.1 - 1e-165 551.8 0.0 1.2e-165 551.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CEG37156.1 - 2e-06 27.1 0.1 3.7e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase ECH_2 PF16113.5 CEG37157.1 - 1.1e-115 386.7 0.0 2e-115 385.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEG37157.1 - 7.4e-31 107.3 0.1 2e-29 102.7 0.0 2.6 1 1 2 3 3 3 1 Enoyl-CoA hydratase/isomerase DUF1765 PF08578.10 CEG37160.1 - 3.7e-18 66.2 1.6 1.2e-17 64.5 1.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) C2 PF00168.30 CEG37160.1 - 6.9e-09 35.9 0.0 2.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain PH PF00169.29 CEG37160.1 - 4.7e-08 33.5 0.4 1.4e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 PH domain DUF1825 PF08855.10 CEG37160.1 - 0.025 14.5 0.6 0.089 12.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) DUF2457 PF10446.9 CEG37160.1 - 6.6 5.8 6.0 12 4.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FKBP_C PF00254.28 CEG37165.1 - 7.5e-34 115.9 0.0 1.5e-33 115.0 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ric8 PF10165.9 CEG37166.1 - 1.2e-15 57.6 0.4 1.5e-15 57.2 0.4 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Glyco_transf_20 PF00982.21 CEG37167.1 - 3.1e-133 444.9 0.0 4.6e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG37167.1 - 1.9e-43 148.3 0.0 1.8e-39 135.2 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase TPR_14 PF13428.6 CEG37169.1 - 4.6e-19 67.5 11.6 0.00047 20.7 0.0 7.9 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37169.1 - 1.3e-16 60.8 15.7 0.00018 21.9 0.0 7.8 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37169.1 - 2.9e-16 58.5 0.1 2.5e-06 27.1 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37169.1 - 3e-16 58.1 5.5 1.8e-05 24.5 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG37169.1 - 9.2e-14 51.8 18.1 0.0038 17.8 0.2 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG37169.1 - 1.9e-13 49.4 2.4 0.0013 18.7 0.0 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG37169.1 - 8.3e-09 35.5 3.2 0.74 10.6 0.0 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG37169.1 - 1.1e-08 34.6 2.5 0.066 12.9 0.2 6.4 7 1 0 7 7 7 2 TPR repeat ANAPC3 PF12895.7 CEG37169.1 - 2.9e-07 30.6 11.1 0.0019 18.4 0.0 5.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CEG37169.1 - 1e-06 28.9 16.9 0.0079 16.5 0.2 6.8 5 2 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG37169.1 - 2.3e-06 27.2 7.0 0.11 12.6 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG37169.1 - 1.3e-05 25.2 2.3 2.3 8.8 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG37169.1 - 5.2e-05 23.3 6.8 0.057 13.6 0.1 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 CEG37169.1 - 0.00039 20.2 2.9 1.3 8.7 0.2 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEG37169.1 - 0.001 18.8 1.0 0.032 14.1 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CEG37169.1 - 0.0038 16.9 0.1 0.013 15.1 0.1 1.9 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 CEG37169.1 - 0.005 16.1 6.2 0.29 10.3 0.0 3.8 2 1 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.6 CEG37169.1 - 0.0051 16.6 1.7 0.14 11.8 0.0 3.1 3 1 0 3 3 3 1 Outer membrane lipoprotein BTAD PF03704.17 CEG37169.1 - 0.0088 16.5 3.1 0.1 13.0 0.3 3.5 1 1 4 5 5 5 1 Bacterial transcriptional activator domain DUF5113 PF17140.4 CEG37169.1 - 0.014 15.2 1.3 5.5 6.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) TPR_20 PF14561.6 CEG37169.1 - 0.017 15.5 4.4 4.1 7.8 0.0 4.8 5 1 1 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG37169.1 - 0.026 14.6 0.5 6.8 6.9 0.1 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_18 PF13512.6 CEG37169.1 - 0.046 13.8 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 CEG37169.1 - 0.61 10.5 2.3 31 5.1 0.0 4.1 4 0 0 4 4 4 0 PPR repeat TPR_3 PF07720.12 CEG37169.1 - 3.2 7.8 5.4 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CEG37169.1 - 3.9 7.6 9.0 6.3 6.9 0.1 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Orn_Arg_deC_N PF02784.16 CEG37170.1 - 9.8e-75 251.1 0.0 1.3e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEG37170.1 - 3.2e-16 59.3 0.0 5.1e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 CEG37170.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain PIP5K PF01504.18 CEG37177.1 - 4.1e-65 219.7 0.1 1.4e-63 214.7 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 CEG37177.1 - 0.66 9.0 11.7 2.5 7.1 11.7 1.7 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region HTH_psq PF05225.16 CEG37178.1 - 0.052 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Hva1_TUDOR PF11160.8 CEG37178.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain Ricin_B_lectin PF00652.22 CEG37184.1 - 6.2e-15 55.6 1.6 1.4e-14 54.5 1.7 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 CEG37184.1 - 5.6e-08 32.7 0.8 1.9e-06 27.7 0.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RicinB_lectin_2 PF14200.6 CEG37184.1 - 7e-07 29.9 2.1 0.018 15.8 0.1 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 CEG37184.1 - 0.00035 20.2 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain GcpE PF04551.14 CEG37184.1 - 0.0055 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 GcpE protein AAA_5 PF07728.14 CEG37185.1 - 8.8e-43 145.6 0.0 1.4e-37 128.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Chromo PF00385.24 CEG37185.1 - 2.6e-11 43.2 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.6 CEG37185.1 - 1.5e-05 25.5 0.0 0.011 16.1 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Mtf2_C PF14061.6 CEG37185.1 - 0.0022 18.1 0.1 0.0046 17.1 0.1 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 AAA_22 PF13401.6 CEG37185.1 - 0.0049 17.1 0.1 0.25 11.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CEG37185.1 - 0.0084 16.3 0.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG37185.1 - 0.013 16.0 0.1 0.15 12.6 0.1 2.3 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 CEG37185.1 - 0.028 14.3 0.2 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CEG37185.1 - 0.034 14.4 0.1 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG37185.1 - 0.073 13.2 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 CEG37185.1 - 0.075 12.4 0.1 0.31 10.4 0.0 1.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 CEG37185.1 - 0.08 13.1 0.1 1.6 8.9 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.29 CEG37185.1 - 0.091 13.2 0.1 5.3 7.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CEG37185.1 - 0.096 12.1 0.7 10 5.4 0.1 3.2 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CEG37185.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CEG37185.1 - 0.18 12.2 0.0 1.5 9.2 0.0 2.4 3 0 0 3 3 3 0 RNA helicase zf_CCCH_4 PF18345.1 CEG37188.1 - 3e-07 30.3 3.2 7.8e-07 28.9 3.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEG37188.1 - 1.4e-05 24.8 1.2 3.5e-05 23.6 1.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG37188.1 - 0.00013 21.7 3.9 0.0013 18.5 1.4 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG37188.1 - 0.0025 18.2 2.1 0.0025 18.2 2.1 2.2 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Methyltransf_32 PF13679.6 CEG37188.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH_3 PF15663.5 CEG37188.1 - 0.015 15.5 2.4 0.11 12.7 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger containing family RasGAP PF00616.19 CEG37190.1 - 1.4e-12 47.7 0.7 1.2e-10 41.4 0.2 2.1 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase YodL PF14191.6 CEG37190.1 - 0.15 12.9 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 YodL-like SIP1 PF04938.12 CEG37192.1 - 2.8e-55 187.4 0.1 3.5e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2095 PF09868.9 CEG37193.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DEAD PF00270.29 CEG37194.1 - 9e-49 165.6 0.7 1.6e-48 164.8 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG37194.1 - 5.9e-22 78.1 0.0 3.9e-19 69.0 0.0 3.8 4 1 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEG37194.1 - 2.2e-17 63.0 0.6 6.8e-17 61.5 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEG37194.1 - 1.2e-08 35.1 0.0 3.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEG37194.1 - 0.018 15.3 1.2 0.14 12.4 1.2 2.4 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 CEG37195.1 - 3.7e-153 510.7 14.4 4.3e-153 510.5 14.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.25 CEG37197.1 - 2.4e-47 160.9 0.0 3.1e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG37197.1 - 2.1e-31 109.3 0.0 2.9e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG37197.1 - 6.5e-13 49.0 0.4 1.1e-12 48.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG37197.1 - 0.00045 19.8 0.1 0.011 15.2 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 CEG37197.1 - 0.001 19.6 0.2 0.0021 18.6 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 CEG37197.1 - 0.0022 17.9 0.7 0.0059 16.5 0.8 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 CEG37197.1 - 0.0043 16.2 0.2 0.0066 15.6 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CEG37197.1 - 0.005 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 CEG37197.1 - 0.0099 15.8 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 CEG37197.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEG37197.1 - 0.022 15.2 0.2 0.037 14.4 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 CEG37197.1 - 0.027 13.5 0.1 0.062 12.3 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 CEG37197.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase YjeF_N PF03853.15 CEG37197.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.8 CEG37197.1 - 0.11 12.2 2.4 0.38 10.6 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 CEG37197.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2564 PF10819.8 CEG37197.1 - 0.24 11.8 0.7 0.57 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) HA2 PF04408.23 CEG37198.1 - 1.1e-24 86.7 0.0 1.1e-24 86.7 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG37198.1 - 3e-23 82.0 0.0 6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG37198.1 - 1.6e-13 50.9 0.0 6.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.23 CEG37198.1 - 9.9e-11 41.8 0.3 2.3e-10 40.7 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CEG37198.1 - 5e-07 30.1 0.1 1.4e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CEG37198.1 - 1.3e-06 28.3 0.1 2.8e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CEG37198.1 - 0.0045 17.3 0.2 0.01 16.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEG37198.1 - 0.0062 15.6 0.1 0.02 14.0 0.1 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 CEG37198.1 - 0.0068 16.5 0.5 5.8 7.0 0.0 3.0 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 CEG37198.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEG37198.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CEG37198.1 - 0.028 14.4 0.8 0.28 11.2 0.3 2.6 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CEG37198.1 - 0.04 13.4 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 CEG37198.1 - 0.061 13.3 0.1 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Microtubule binding DUF1418 PF07214.12 CEG37198.1 - 0.07 13.0 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) AAA_7 PF12775.7 CEG37198.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CEG37198.1 - 0.097 13.2 0.4 1.3 9.5 0.3 2.6 1 1 0 2 2 2 0 ABC transporter zf-H2C2_2 PF13465.6 CEG37199.1 - 2.5e-18 65.6 23.1 6.6e-09 35.8 0.6 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEG37199.1 - 8e-18 63.8 26.3 4.8e-05 23.6 0.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG37199.1 - 3.4e-14 52.3 26.0 0.0057 17.4 1.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 CEG37199.1 - 2.1e-07 31.4 12.9 0.01 16.5 0.8 4.1 2 1 2 4 4 4 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEG37199.1 - 2.4e-06 27.7 9.3 0.0082 16.4 7.2 3.1 1 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CEG37199.1 - 7.4e-06 26.1 4.5 0.6 10.5 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG37199.1 - 8.6e-05 22.8 6.3 0.26 11.8 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CEG37199.1 - 0.0019 18.0 13.1 0.13 12.2 0.1 4.3 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 CEG37199.1 - 0.0019 17.9 16.4 0.49 10.2 1.4 5.1 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CEG37199.1 - 0.0059 16.8 11.2 0.12 12.6 2.7 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_11 PF16622.5 CEG37199.1 - 0.044 13.6 7.6 2.2 8.1 1.4 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-TRAF PF02176.18 CEG37199.1 - 0.58 10.9 8.0 0.09 13.5 2.0 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-LYAR PF08790.11 CEG37199.1 - 1.6 8.7 8.7 1.9 8.5 0.7 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 CEG37199.1 - 8.9 6.5 9.3 2.8 8.1 0.2 3.5 4 0 0 4 4 4 0 Zic proteins zinc finger domain DUF4505 PF14956.6 CEG37201.1 - 4.8e-40 137.2 0.0 6.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) DDE_1 PF03184.19 CEG37202.1 - 0.034 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease PITH PF06201.13 CEG37204.1 - 3.8e-38 131.1 0.0 5.1e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 PITH domain Zip PF02535.22 CEG37204.1 - 0.33 10.1 0.7 0.31 10.2 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RCC1 PF00415.18 CEG37205.1 - 3e-58 194.2 12.6 2.4e-14 53.7 0.0 5.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG37205.1 - 2.3e-34 116.5 36.0 5.1e-10 38.9 1.4 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CEG37205.1 - 0.0012 18.6 1.5 0.3 10.8 0.0 2.8 2 1 1 3 3 3 2 TUP1-like enhancer of split ABC_tran PF00005.27 CEG37206.1 - 4.8e-36 124.3 0.0 9.7e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CEG37206.1 - 5.3e-32 111.6 2.7 6.6e-32 111.2 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CEG37206.1 - 5.6e-10 39.0 0.5 1.3e-07 31.3 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG37206.1 - 3.6e-06 27.5 0.9 7e-05 23.3 0.9 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 CEG37206.1 - 0.00093 19.0 0.0 0.0032 17.3 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG37206.1 - 0.0029 17.9 0.4 0.036 14.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 CEG37206.1 - 0.0049 16.6 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 CEG37206.1 - 0.0074 16.4 0.3 0.02 15.0 0.1 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CEG37206.1 - 0.0079 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin G-alpha PF00503.20 CEG37206.1 - 0.0091 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.6 CEG37206.1 - 0.012 16.2 0.1 0.065 13.8 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 CEG37206.1 - 0.017 15.0 0.3 0.064 13.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CEG37206.1 - 0.02 14.1 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 CEG37206.1 - 0.042 13.2 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CEG37206.1 - 0.079 12.7 0.0 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEG37206.1 - 0.12 12.0 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEG37206.1 - 0.12 12.6 0.8 0.3 11.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG37206.1 - 0.13 12.4 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CEG37206.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 CEG37206.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 CEG37206.1 - 0.24 11.7 0.7 4.2 7.7 0.7 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sod_Fe_C PF02777.18 CEG37207.1 - 6.2e-41 138.7 0.1 1.5e-40 137.5 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CEG37207.1 - 2.2e-27 95.3 0.9 4e-27 94.5 0.9 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Gar1 PF04410.14 CEG37209.1 - 2.8e-34 118.1 0.1 2.8e-34 118.1 0.1 1.9 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region UPF0183 PF03676.14 CEG37210.1 - 6.8e-100 335.1 0.0 7.8e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Robl_LC7 PF03259.17 CEG37212.1 - 2.5e-15 56.0 0.0 2.8e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CEG37212.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.2 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 MCM_bind PF09739.9 CEG37213.1 - 2.5e-94 316.8 10.4 8e-92 308.6 10.8 2.2 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Torsin PF06309.11 CEG37215.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Torsin Methyltransf_23 PF13489.6 CEG37216.1 - 1.1e-20 74.1 0.1 1.4e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG37216.1 - 3e-14 53.5 0.1 5.4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG37216.1 - 1.3e-13 51.4 0.1 2.3e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG37216.1 - 8.9e-11 41.6 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CEG37216.1 - 6.6e-08 32.5 0.0 9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG37216.1 - 1.3e-07 32.2 0.0 2.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CEG37216.1 - 0.00097 18.8 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF3013 PF11217.8 CEG37216.1 - 0.06 13.2 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) CBS PF00571.28 CEG37218.1 - 4.4e-11 43.1 0.3 1.1e-05 25.8 0.1 2.8 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.12 CEG37218.1 - 2e-06 27.9 0.1 4.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Mannosyl_trans PF05007.13 CEG37222.1 - 3.6e-77 259.7 19.9 6e-77 259.0 19.9 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CEG37222.1 - 1.2e-12 47.6 26.2 1.9e-12 46.9 26.2 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CEG37222.1 - 1.1e-05 25.2 7.8 1.1e-05 25.2 7.8 3.1 1 1 0 2 2 2 1 Glycosyltransferase family 87 Med12-LCEWAV PF12145.8 CEG37223.1 - 5.7e-05 22.1 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DUF3915 PF13054.6 CEG37223.1 - 2.3 8.2 3.9 5.3 7.1 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) EF-hand_6 PF13405.6 CEG37224.1 - 2e-15 55.3 3.2 0.0037 17.1 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CEG37224.1 - 8.3e-15 53.2 7.8 0.00014 21.2 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG37224.1 - 2.8e-14 53.3 3.9 4.2e-07 30.3 0.4 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEG37224.1 - 1.2e-08 34.6 11.7 0.0063 16.3 0.5 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG37224.1 - 2.2e-07 30.1 1.6 0.016 14.7 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CEG37224.1 - 0.0051 16.8 2.1 0.17 11.9 0.0 2.7 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG37224.1 - 0.051 13.9 1.7 2.4 8.5 0.0 2.6 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CEG37224.1 - 0.19 11.7 1.4 3.7 7.5 0.0 2.8 2 1 0 3 3 3 0 Caleosin related protein TFIID-18kDa PF02269.16 CEG37225.1 - 3e-20 72.0 0.2 4.8e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 CEG37225.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CBFB_NFYA PF02045.15 CEG37228.1 - 2.3e-27 95.4 8.5 4.3e-27 94.5 8.5 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CTP_transf_1 PF01148.20 CEG37230.1 - 5.2e-41 141.2 19.2 1.5e-37 129.8 14.4 2.7 2 1 0 2 2 2 2 Cytidylyltransferase family DUF1295 PF06966.12 CEG37230.1 - 0.018 14.6 0.6 0.052 13.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) SNAP PF14938.6 CEG37231.1 - 9.9e-14 51.4 9.2 1.3e-13 51.0 9.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF5326 PF17260.2 CEG37231.1 - 0.77 9.9 4.0 1.7 8.8 4.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Pkinase PF00069.25 CEG37232.1 - 4.8e-57 193.3 0.0 7.3e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 CEG37232.1 - 1.5e-53 182.1 0.0 2.6e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 CEG37232.1 - 1e-36 126.6 0.0 1.5e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG37232.1 - 2.2e-06 27.2 0.0 5.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG37232.1 - 0.00019 20.3 0.8 0.00038 19.4 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CEG37232.1 - 0.019 14.6 0.7 0.05 13.2 0.6 1.8 2 0 0 2 2 2 0 RIO1 family NECFESHC PF16621.5 CEG37232.1 - 0.066 13.2 0.3 0.28 11.2 0.3 2.1 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 DUF977 PF06163.11 CEG37232.1 - 0.1 12.6 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sema PF01403.19 CEG37233.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Sema domain HMw1_D2 PF18254.1 CEG37235.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 HMW1 domain 2 Ank_2 PF12796.7 CEG37236.1 - 1.5e-13 51.1 2.1 1.5e-08 35.1 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG37236.1 - 5e-10 39.7 0.9 3.6e-05 24.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG37236.1 - 9.6e-10 37.9 0.8 9.5e-05 22.5 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.26 CEG37236.1 - 1.2e-07 31.6 11.3 2.8e-06 27.3 3.4 2.8 2 0 0 2 2 2 2 WW domain Ank_5 PF13857.6 CEG37236.1 - 5.2e-06 26.6 1.4 0.00012 22.3 0.3 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG37236.1 - 6.3e-06 26.4 2.7 0.00023 21.5 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeat IQ PF00612.27 CEG37236.1 - 0.005 16.5 0.1 0.017 14.9 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Syntaxin-18_N PF10496.9 CEG37237.1 - 1.2e-05 25.5 0.0 1.2e-05 25.5 0.0 3.4 3 1 1 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus Ly49 PF08391.10 CEG37237.1 - 0.085 13.2 1.6 0.16 12.3 1.0 1.8 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Synaptobrevin PF00957.21 CEG37237.1 - 2 8.3 7.6 2 8.3 1.4 2.8 3 0 0 3 3 3 0 Synaptobrevin HBS1_N PF08938.10 CEG37237.1 - 2.2 8.7 5.0 0.7 10.2 0.4 2.4 3 0 0 3 3 3 0 HBS1 N-terminus Guanylate_cyc PF00211.20 CEG37239.1 - 1.3e-07 31.4 0.0 3.1e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 CEG37239.1 - 0.0014 17.9 0.3 0.0014 17.9 0.3 1.5 2 0 0 2 2 2 1 Ion transport protein MetJ PF01340.20 CEG37239.1 - 0.14 12.2 1.0 0.37 10.8 1.0 1.7 1 0 0 1 1 1 0 Met Apo-repressor, MetJ ABC_membrane_2 PF06472.15 CEG37239.1 - 0.15 11.5 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 ATP_synth_reg PF14960.6 CEG37240.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase regulation CDC73_C PF05179.14 CEG37241.1 - 1.6e-43 148.1 0.9 1.6e-43 148.1 0.9 1.8 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 CEG37241.1 - 7e-14 51.8 15.2 2.4e-06 27.1 13.4 2.2 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Glft2_N PF17994.1 CEG37243.1 - 0.043 13.7 0.3 0.085 12.8 0.3 1.4 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal tRNA-synt_1 PF00133.22 CEG37245.1 - 1.2e-180 601.8 0.0 1.4e-179 598.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEG37245.1 - 1.6e-32 112.6 0.1 4e-32 111.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEG37245.1 - 3.1e-13 49.3 0.1 2.4e-06 26.6 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEG37245.1 - 2.4e-11 43.5 0.2 3.1e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CEG37245.1 - 0.0027 17.1 0.0 1.3 8.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain DUF1153 PF06627.11 CEG37245.1 - 0.041 14.0 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) tRNA-synt_1d PF00750.19 CEG37245.1 - 0.087 11.8 0.1 0.91 8.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) Val_tRNA-synt_C PF10458.9 CEG37245.1 - 7 7.0 10.9 0.13 12.6 3.1 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Pro_isomerase PF00160.21 CEG37246.1 - 2.5e-21 76.6 0.1 4.2e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CEG37246.1 - 1.6e-10 40.7 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 CEG37247.1 - 6.4e-07 29.6 9.9 9.4e-05 22.6 1.2 3.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37247.1 - 1.6e-06 27.7 7.7 5.2e-05 22.9 4.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG37247.1 - 1.4e-05 24.8 11.5 3.5e-05 23.5 1.6 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37247.1 - 7.6e-05 22.5 7.9 0.00067 19.6 3.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.27 CEG37247.1 - 0.00032 20.2 10.0 0.057 13.2 1.4 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif TPR_8 PF13181.6 CEG37247.1 - 0.0032 17.6 3.0 0.0032 17.6 3.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG37247.1 - 0.39 11.2 3.8 2 9.0 0.9 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LNS2 PF08235.13 CEG37248.1 - 8.7e-53 179.1 0.0 1.3e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CEG37248.1 - 3e-25 88.1 0.2 1.2e-24 86.2 0.2 2.1 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CEG37248.1 - 2.4e-08 34.0 0.0 6.9e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF2794 PF10984.8 CEG37252.1 - 0.092 12.9 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2794) LRAT PF04970.13 CEG37253.1 - 5.8e-09 36.3 0.1 2.6e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Ribosomal_S25 PF03297.15 CEG37253.1 - 0.033 14.4 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 S25 ribosomal protein P21-Arc PF04062.14 CEG37254.1 - 1.8e-69 233.3 0.0 2e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos_3 PF14582.6 CEG37254.1 - 0.0017 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Coatomer_E PF04733.14 CEG37255.1 - 6.6e-75 252.2 0.1 7.4e-75 252.0 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CEG37255.1 - 1e-05 26.0 2.0 0.16 12.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG37255.1 - 0.00052 20.6 0.5 6.7 7.4 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37255.1 - 0.00054 19.9 0.9 0.39 10.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG37255.1 - 0.0047 17.2 3.9 1.1 9.6 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37255.1 - 0.0061 16.3 3.1 0.48 10.3 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG37255.1 - 0.011 15.7 6.0 0.66 10.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37255.1 - 0.017 15.9 0.7 15 6.7 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat LSDAT_prok PF18171.1 CEG37255.1 - 0.048 12.9 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote PPR PF01535.20 CEG37255.1 - 0.28 11.5 0.9 29 5.2 0.1 3.4 3 0 0 3 3 3 0 PPR repeat CUE PF02845.16 CEG37256.1 - 2.8e-09 36.5 0.9 4.4e-08 32.7 0.0 3.0 3 0 0 3 3 3 1 CUE domain zf-RING_2 PF13639.6 CEG37256.1 - 1.9e-05 24.9 9.0 9.7e-05 22.6 4.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CEG37256.1 - 9.9e-05 22.3 2.9 9.9e-05 22.3 2.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG37256.1 - 0.0004 20.2 5.1 0.0004 20.2 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG37256.1 - 0.00082 19.2 5.9 0.00082 19.2 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG37256.1 - 0.0017 18.1 5.4 0.0017 18.1 5.4 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CEG37256.1 - 0.16 11.9 10.1 0.99 9.4 10.1 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 CEG37256.1 - 0.62 9.9 2.0 2.9 7.8 1.7 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CEG37256.1 - 1.3 9.4 9.0 1.6 9.1 5.4 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEG37256.1 - 1.8 8.5 11.8 3.1 7.7 4.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF485 PF04341.12 CEG37256.1 - 3.2 7.8 6.0 3.7 7.6 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Zf_RING PF16744.5 CEG37256.1 - 3.8 7.7 5.5 0.58 10.3 1.1 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_4 PF14447.6 CEG37256.1 - 8.6 6.3 10.7 1.1 9.2 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DAGAT PF03982.13 CEG37257.1 - 1.1e-33 116.5 0.1 2.3e-33 115.4 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Pkinase PF00069.25 CEG37258.1 - 1.4e-42 145.9 0.0 1.6e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37258.1 - 1.3e-26 93.5 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG37258.1 - 0.003 16.5 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG37258.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG37258.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG37258.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CEG37258.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WAPL PF07814.13 CEG37260.1 - 5e-09 35.4 23.4 5e-09 35.4 23.4 3.6 2 2 1 3 3 3 1 Wings apart-like protein regulation of heterochromatin ubiquitin PF00240.23 CEG37265.1 - 0.00062 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.8 CEG37265.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pkinase_Tyr PF07714.17 CEG37267.1 - 1.8e-30 106.1 0.0 1.9e-29 102.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG37267.1 - 1.2e-24 87.1 0.0 6.8e-12 45.3 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain NADH_dehy_S2_C PF06444.11 CEG37269.1 - 0.091 13.3 0.2 0.1 13.1 0.2 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Asp_protease_2 PF13650.6 CEG37271.1 - 1.7e-07 31.8 0.0 2.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG37271.1 - 3.1e-07 30.8 0.0 4.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CEG37271.1 - 0.11 12.8 0.0 1.8 8.9 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1084 PF06454.11 CEG37273.1 - 0.00046 19.7 11.7 0.00073 19.0 8.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1084) DUF1516 PF07457.11 CEG37273.1 - 0.46 10.7 3.7 5.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) DHHA2 PF02833.14 CEG37274.1 - 9.2e-20 71.3 0.1 1.9e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CEG37274.1 - 5.4e-12 45.8 0.4 1.2e-11 44.8 0.4 1.4 1 0 0 1 1 1 1 DHH family Cpn60_TCP1 PF00118.24 CEG37275.1 - 1.2e-139 466.1 12.0 2e-74 251.0 3.9 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family BslA PF17735.1 CEG37275.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Biofilm surface layer A DUF3338 PF11819.8 CEG37276.1 - 0.056 13.4 5.6 0.21 11.6 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) TraI_2B PF18340.1 CEG37276.1 - 0.21 11.7 1.0 0.62 10.2 0.1 2.2 1 1 1 2 2 2 0 DNA relaxase TraI 2B/2B-like domain Cep57_MT_bd PF06657.13 CEG37276.1 - 7.2 7.1 8.4 3.4 8.2 0.2 3.4 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ank_2 PF12796.7 CEG37278.1 - 6.8e-40 135.5 6.2 1.3e-12 48.2 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG37278.1 - 3.2e-22 78.6 2.4 4.8e-09 36.6 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG37278.1 - 3.5e-20 69.9 0.4 6.4e-05 23.0 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEG37278.1 - 5.4e-19 68.0 1.0 4.6e-05 23.6 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG37278.1 - 2.8e-18 65.5 1.3 1.7e-05 25.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat DUF1843 PF08898.10 CEG37278.1 - 0.014 15.9 0.6 0.2 12.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) GTP_EFTU PF00009.27 CEG37279.1 - 2.1e-59 200.4 0.0 5.5e-59 199.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CEG37279.1 - 4.7e-36 123.2 0.1 9.8e-36 122.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CEG37279.1 - 6.2e-34 115.9 0.1 5.7e-33 112.8 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 CEG37279.1 - 3.7e-25 87.8 0.0 1.2e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEG37279.1 - 1.6e-10 41.2 0.1 5.3e-10 39.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEG37279.1 - 3.9e-07 29.9 0.1 1.2e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CEG37279.1 - 0.00083 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 CEG37279.1 - 0.0013 19.2 0.0 0.33 11.5 0.0 3.1 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain DUF442 PF04273.13 CEG37279.1 - 0.032 14.3 0.0 0.89 9.7 0.0 2.6 2 0 0 2 2 2 0 Putative phosphatase (DUF442) AIG1 PF04548.16 CEG37279.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DnaJ PF00226.31 CEG37280.1 - 5.8e-22 77.6 0.5 1.1e-21 76.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain PGC7_Stella PF15549.6 CEG37280.1 - 5.7 6.9 9.3 3.8 7.5 6.9 1.8 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain DnaJ PF00226.31 CEG37281.1 - 8.3e-17 61.1 0.6 2.6e-16 59.5 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain Monooxygenase_B PF04744.12 CEG37281.1 - 0.079 11.8 0.2 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 Monooxygenase subunit B protein Phage_holin_3_6 PF07332.11 CEG37281.1 - 1.2 9.2 7.5 3.6 7.7 4.5 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RabGAP-TBC PF00566.18 CEG37282.1 - 1e-10 41.6 0.4 1e-10 41.6 0.4 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 CEG37283.1 - 1.4e-21 76.8 4.1 1.3e-11 44.9 0.1 3.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG37283.1 - 3.4e-14 51.6 6.3 0.0015 18.8 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CEG37283.1 - 4.4e-11 43.1 7.4 4.1e-07 30.4 0.1 4.6 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG37283.1 - 8.5e-09 35.5 8.0 0.033 14.6 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 CEG37283.1 - 1.1e-06 28.8 5.1 0.28 11.6 0.2 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) HECT PF00632.25 CEG37283.1 - 9.5e-06 25.3 4.1 5.7e-05 22.7 0.0 2.8 2 1 1 3 3 3 1 HECT-domain (ubiquitin-transferase) PHD PF00628.29 CEG37283.1 - 0.00015 21.6 6.8 0.00015 21.6 6.8 2.4 2 0 0 2 2 2 1 PHD-finger TFIIA PF03153.13 CEG37283.1 - 0.39 10.7 25.7 0.68 9.9 25.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAP7 PF05672.11 CEG37283.1 - 1.9 8.1 41.7 3.1 7.5 41.7 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Exonuc_VII_L PF02601.15 CEG37283.1 - 8.2 5.9 19.7 15 5.1 19.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mito_carr PF00153.27 CEG37284.1 - 1.8e-65 216.9 5.7 6.7e-22 77.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEG37284.1 - 0.0082 15.3 0.9 0.028 13.6 0.3 2.1 1 1 0 2 2 2 1 Gammaproteobacterial serine protease WW PF00397.26 CEG37287.1 - 0.0041 17.2 1.8 0.0091 16.1 0.2 2.4 2 0 0 2 2 2 1 WW domain Exo_endo_phos PF03372.23 CEG37288.1 - 3.7e-06 26.6 0.1 1.2e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mito_carr PF00153.27 CEG37289.1 - 4.8e-28 96.9 2.4 2.9e-13 49.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ZapA PF05164.13 CEG37293.1 - 0.0084 16.5 2.5 0.0084 16.5 2.5 1.6 2 0 0 2 2 2 1 Cell division protein ZapA FOXP-CC PF16159.5 CEG37293.1 - 2.2 9.0 5.9 0.46 11.1 1.4 2.1 2 1 0 2 2 2 0 FOXP coiled-coil domain adh_short PF00106.25 CEG37295.1 - 2.8e-28 98.7 0.1 1.4e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEG37295.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG37295.1 - 3.4e-08 33.6 0.1 5.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG37295.1 - 0.00025 20.6 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 CEG37295.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 CEG37295.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 CEG37295.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.25 CEG37296.1 - 1.4e-33 116.0 0.0 1.3e-29 103.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEG37296.1 - 1.3e-19 70.7 0.0 2.3e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG37296.1 - 1.6e-08 34.7 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG37296.1 - 1.8e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 CEG37296.1 - 3.9e-05 23.0 0.0 5.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CEG37296.1 - 0.0043 16.9 0.1 0.0064 16.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 CEG37296.1 - 0.024 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 CEG37296.1 - 0.025 14.5 0.0 0.081 12.8 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CEG37296.1 - 0.075 12.4 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 CEG37296.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase N2227 PF07942.12 CEG37296.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein E1_dh PF00676.20 CEG37296.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component AAA_16 PF13191.6 CEG37297.1 - 0.12 12.7 0.0 0.48 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CEG37297.1 - 0.18 12.1 0.0 1.5 9.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain Plasmid_stab_B PF10784.9 CEG37298.1 - 0.041 13.7 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Plasmid stability protein UCH PF00443.29 CEG37299.1 - 3.6e-49 167.6 1.5 8.9e-49 166.3 0.4 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG37299.1 - 4e-22 79.2 0.5 1.5e-21 77.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG37299.1 - 0.014 15.1 0.0 0.052 13.3 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin family SLC35F PF06027.12 CEG37301.1 - 3.4e-55 187.7 28.6 4e-55 187.4 28.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CEG37301.1 - 5.4e-11 42.8 35.9 2.1e-07 31.2 16.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CEG37301.1 - 2.1e-08 33.5 8.4 2.1e-08 33.5 8.4 1.6 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Xpo1 PF08389.12 CEG37302.1 - 3.9e-19 69.2 0.3 1.8e-18 67.0 0.2 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 CEG37302.1 - 0.0015 18.4 0.2 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Hpr_kinase_C PF07475.12 CEG37302.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Fringe PF02434.16 CEG37303.1 - 2.8e-15 56.5 2.7 3.9e-15 56.0 2.7 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CEG37303.1 - 1.3e-05 25.1 0.6 1.9e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF2203 PF09969.9 CEG37304.1 - 0.23 12.2 0.3 0.23 12.2 0.3 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) FAM76 PF16046.5 CEG37304.1 - 0.89 8.9 7.4 7.1 5.9 7.4 1.9 1 1 0 1 1 1 0 FAM76 protein CAP PF00188.26 CEG37305.1 - 2.7e-19 70.2 0.5 4.1e-19 69.6 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PA PF02225.22 CEG37306.1 - 1.7e-13 50.4 0.2 3.4e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 PA domain zf-RING_2 PF13639.6 CEG37306.1 - 1.7e-12 47.4 7.3 1.7e-12 47.4 7.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG37306.1 - 2e-08 33.9 7.7 2e-08 33.9 7.7 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG37306.1 - 3.2e-08 33.7 5.1 3.2e-08 33.7 5.1 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG37306.1 - 3.7e-07 29.7 3.0 3.7e-07 29.7 3.0 2.6 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEG37306.1 - 9e-06 25.5 5.8 9e-06 25.5 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG37306.1 - 1.3e-05 24.7 5.2 1.3e-05 24.7 5.2 2.4 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEG37306.1 - 4e-05 23.4 5.0 4e-05 23.4 5.0 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG37306.1 - 6.6e-05 22.7 6.8 6.6e-05 22.7 6.8 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG37306.1 - 0.00055 19.9 1.8 0.0012 18.9 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 CEG37306.1 - 0.0011 19.1 1.8 0.0011 19.1 1.8 1.8 2 1 0 2 2 1 1 PHD-zinc-finger like domain zf-RING_UBOX PF13445.6 CEG37306.1 - 0.002 18.1 1.7 0.002 18.1 1.7 3.0 2 2 1 3 3 3 1 RING-type zinc-finger zf-HC5HC2H PF13771.6 CEG37306.1 - 0.0021 18.3 2.6 0.0021 18.3 2.6 2.1 2 1 1 3 3 3 1 PHD-like zinc-binding domain zf-RING_5 PF14634.6 CEG37306.1 - 0.012 15.6 7.5 0.012 15.6 7.5 2.7 2 1 1 3 3 3 0 zinc-RING finger domain FANCL_C PF11793.8 CEG37306.1 - 0.02 15.1 6.9 0.47 10.7 6.9 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 CEG37306.1 - 0.43 10.7 9.2 0.098 12.8 3.1 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 CTU2 PF10288.9 CEG37306.1 - 1.7 8.9 6.9 30 4.9 2.6 3.0 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PHD PF00628.29 CEG37306.1 - 5.1 7.1 9.0 57 3.7 0.0 2.9 2 1 0 2 2 2 0 PHD-finger TFIIS_C PF01096.18 CEG37307.1 - 1.6e-17 63.0 1.8 1.6e-17 63.0 1.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 CEG37307.1 - 9.8e-05 22.3 12.2 0.0015 18.5 1.9 2.9 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CEG37307.1 - 0.00088 18.7 15.7 0.0063 16.0 4.0 3.0 2 1 0 2 2 2 2 TFIIB zinc-binding C1_1 PF00130.22 CEG37307.1 - 0.0031 17.3 0.8 0.0031 17.3 0.8 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.7 CEG37307.1 - 0.0057 16.6 16.0 0.0094 15.9 0.9 3.3 2 1 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 CEG37307.1 - 0.01 15.7 13.1 0.43 10.5 2.3 3.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.12 CEG37307.1 - 0.015 15.4 1.4 0.015 15.4 1.4 2.9 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CEG37307.1 - 0.019 14.8 1.0 0.019 14.8 1.0 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 IBR PF01485.21 CEG37307.1 - 0.023 14.9 9.4 0.74 10.1 1.3 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Terminase_GpA PF05876.12 CEG37307.1 - 0.033 12.8 2.0 1.4 7.4 0.5 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-ribbon_3 PF13248.6 CEG37307.1 - 0.038 13.4 17.7 0.52 9.8 4.8 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEG37307.1 - 0.059 13.4 11.5 0.37 10.8 1.2 2.7 2 1 1 3 3 3 0 zinc-ribbons DUF2387 PF09526.10 CEG37307.1 - 0.066 13.4 0.8 0.066 13.4 0.8 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.8 CEG37307.1 - 0.091 12.4 0.0 0.091 12.4 0.0 2.3 4 0 0 4 4 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-RING_7 PF02591.15 CEG37307.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 CEG37307.1 - 0.33 11.1 21.4 0.25 11.5 1.0 4.3 3 1 1 4 4 4 0 Zinc ribbon domain HypA PF01155.19 CEG37307.1 - 0.38 10.8 10.0 18 5.4 4.8 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 CEG37307.1 - 0.38 10.9 7.5 5.8 7.2 0.1 3.4 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like tRNA-synt_1f PF01921.18 CEG37307.1 - 0.54 9.1 1.9 0.25 10.2 0.2 1.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf_C2H2_10 PF18414.1 CEG37307.1 - 0.56 9.8 0.1 0.56 9.8 0.1 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger zinc_ribbon_2 PF13240.6 CEG37307.1 - 0.58 9.9 19.6 1.9 8.3 5.4 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 CEG37307.1 - 0.64 10.0 14.3 1.2 9.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DpnI PF06044.12 CEG37307.1 - 0.97 9.0 5.0 5.3 6.6 0.6 2.1 2 0 0 2 2 2 0 Dam-replacing family zf-H2C2_2 PF13465.6 CEG37307.1 - 1 9.9 13.6 2.4 8.8 1.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain Nudix_N_2 PF14803.6 CEG37307.1 - 1.4 8.9 13.9 27 4.8 5.8 4.1 3 1 0 3 3 3 0 Nudix N-terminal DUF2318 PF10080.9 CEG37307.1 - 1.4 9.1 6.2 3 8.0 0.2 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) Zn_ribbon_SprT PF17283.2 CEG37307.1 - 2.3 8.2 13.4 3.7 7.6 4.5 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CEG37307.1 - 2.7 8.0 13.3 0.37 10.7 2.0 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 CEG37307.1 - 2.8 8.1 19.8 0.52 10.4 0.5 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.6 CEG37307.1 - 3.4 7.8 14.4 3 8.0 3.2 2.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 CEG37307.1 - 3.5 8.1 10.9 2.6 8.5 0.7 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ANAPC11 PF12861.7 CEG37307.1 - 4.4 7.4 8.2 0.36 10.9 0.7 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HECT PF00632.25 CEG37308.1 - 3.1e-76 256.8 0.2 5.1e-76 256.1 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 CEG37308.1 - 7.8e-06 25.1 1.2 2.2e-05 23.6 1.2 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Pkinase PF00069.25 CEG37309.1 - 1.8e-69 234.1 0.0 2.5e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37309.1 - 7.3e-32 110.7 0.0 1.2e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG37309.1 - 0.00047 19.6 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG37309.1 - 0.026 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TFIIF_beta PF02270.15 CEG37309.1 - 0.1 12.8 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain Str_synth PF03088.16 CEG37310.1 - 6.7e-18 64.6 0.0 1.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 CEG37310.1 - 4.1e-11 42.9 0.0 1.1e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CEG37310.1 - 0.018 15.0 0.1 1.8 8.8 0.0 3.3 4 0 0 4 4 4 0 NHL repeat PP2C PF00481.21 CEG37311.1 - 3.6e-45 154.6 0.1 1.8e-44 152.4 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG37311.1 - 7e-09 35.6 0.1 1.3e-08 34.7 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C GTP_EFTU PF00009.27 CEG37313.1 - 2.7e-44 151.1 0.3 5.9e-44 149.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG37313.1 - 1e-06 28.8 0.0 0.0015 18.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF1296 PF06972.11 CEG37313.1 - 0.00056 20.0 0.4 0.0014 18.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) E3_UbLigase_EDD PF11547.8 CEG37313.1 - 0.055 13.2 1.1 0.16 11.7 1.1 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD HBS1_N PF08938.10 CEG37313.1 - 0.13 12.6 9.4 0.46 10.8 9.4 2.0 1 1 0 1 1 1 0 HBS1 N-terminus DUF2524 PF10732.9 CEG37313.1 - 1.2 9.5 5.5 3.2 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF1218 PF06749.12 CEG37314.1 - 0.11 13.1 1.1 0.29 11.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) PHD PF00628.29 CEG37316.1 - 1.9e-10 40.5 9.5 3.2e-10 39.7 9.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEG37316.1 - 0.00056 20.1 4.5 0.0015 18.8 4.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain Myb_DNA-binding PF00249.31 CEG37316.1 - 0.0051 17.0 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-HC5HC2H_2 PF13832.6 CEG37316.1 - 0.01 16.0 2.7 0.022 14.9 2.7 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain VWA_N2 PF16164.5 CEG37316.1 - 0.021 14.9 2.2 0.05 13.8 2.2 1.6 1 0 0 1 1 1 0 VWA N-terminal zf-RING_2 PF13639.6 CEG37316.1 - 0.057 13.8 9.5 0.095 13.0 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 CEG37316.1 - 0.085 13.1 2.6 0.2 11.9 2.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_L18p PF00861.22 CEG37322.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast FANCAA PF15146.6 CEG37323.1 - 1.2e-05 24.7 0.5 2.1e-05 23.8 0.5 1.3 1 0 0 1 1 1 1 Fanconi anemia-associated HMw1_D2 PF18254.1 CEG37324.1 - 0.0021 18.4 0.1 0.0025 18.1 0.1 1.2 1 0 0 1 1 1 1 HMW1 domain 2 ATPase_gene1 PF09527.10 CEG37327.1 - 0.085 13.0 1.5 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CTP_transf_1 PF01148.20 CEG37328.1 - 5.7e-42 144.3 15.7 9.8e-42 143.5 15.7 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 CEG37328.1 - 0.011 15.8 0.2 0.011 15.8 0.2 2.6 2 2 1 3 3 3 0 CDP-archaeol synthase RVT_2 PF07727.14 CEG37330.1 - 5e-11 42.7 0.0 6.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YwqJ-deaminase PF14431.6 CEG37330.1 - 0.0019 18.4 0.7 0.0072 16.5 0.7 2.0 1 1 0 1 1 1 1 YwqJ-like deaminase T3SS_needle_E PF08988.10 CEG37330.1 - 0.11 12.7 2.0 0.18 12.0 2.0 1.4 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle gag_pre-integrs PF13976.6 CEG37332.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain FAM220 PF15487.6 CEG37334.1 - 0.035 13.7 0.0 0.039 13.6 0.0 1.0 1 0 0 1 1 1 0 FAM220 family Utp14 PF04615.13 CEG37335.1 - 8.4e-137 457.8 73.8 1.6e-75 255.2 34.5 2.9 1 1 2 3 3 3 2 Utp14 protein RNase_PH PF01138.21 CEG37335.1 - 0.065 13.7 2.0 0.31 11.5 2.0 2.3 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 tRNA-synt_2d PF01409.20 CEG37336.1 - 6.9e-84 281.2 0.1 1e-83 280.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CEG37336.1 - 1.7e-16 60.2 0.1 5.9e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 CEG37336.1 - 2.5e-09 36.8 0.0 9.4e-09 34.9 0.0 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 CEG37336.1 - 7.1e-09 35.4 0.0 4.3e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CEG37336.1 - 5.2e-05 22.5 0.0 0.00016 20.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CEG37336.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ras PF00071.22 CEG37337.1 - 3.7e-42 143.7 0.2 5.2e-42 143.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG37337.1 - 1.9e-27 95.9 0.0 3.2e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG37337.1 - 3.2e-11 43.0 0.2 4.4e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG37337.1 - 0.00017 21.1 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CEG37337.1 - 0.0023 17.2 0.5 0.084 12.0 0.0 2.6 1 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CEG37337.1 - 0.014 15.5 0.1 0.061 13.4 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase Ribosomal_60s PF00428.19 CEG37338.1 - 3.5e-09 37.1 3.5 3.6e-09 37.1 3.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein YjbE PF11106.8 CEG37338.1 - 0.19 12.0 5.4 0.31 11.3 5.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Ribosomal_L22e PF01776.17 CEG37339.1 - 7.2e-46 155.1 0.6 9.3e-46 154.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Pkinase PF00069.25 CEG37340.1 - 9.4e-66 221.9 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37340.1 - 2.1e-36 125.5 0.1 2.8e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 CEG37340.1 - 5.1e-33 113.3 0.1 5.1e-33 113.3 0.1 1.7 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CEG37340.1 - 5.7e-05 22.6 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG37340.1 - 9.2e-05 22.5 0.0 0.034 14.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG37340.1 - 9.3e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CEG37340.1 - 0.0014 18.3 0.1 1.1 8.9 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEG37340.1 - 0.0017 17.7 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG37340.1 - 0.014 14.4 0.7 0.029 13.3 0.7 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Ras PF00071.22 CEG37343.1 - 1.7e-54 183.8 0.0 2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG37343.1 - 4.9e-19 68.7 0.0 7.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG37343.1 - 2.4e-09 36.9 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEG37343.1 - 1.5e-06 28.2 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG37343.1 - 0.00014 21.5 0.1 0.0012 18.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG37343.1 - 0.0057 16.7 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEG37343.1 - 0.0098 15.1 0.1 2.4 7.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit LigT_PEase PF02834.16 CEG37343.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 LigT like Phosphoesterase Frigida PF07899.11 CEG37344.1 - 0.00065 19.1 1.1 5.1 6.3 0.0 3.6 3 0 0 3 3 3 3 Frigida-like protein MA3 PF02847.17 CEG37344.1 - 0.12 12.3 1.7 13 5.8 0.0 3.0 2 2 1 3 3 3 0 MA3 domain TPR_19 PF14559.6 CEG37344.1 - 0.2 12.2 3.1 1.6 9.3 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37344.1 - 0.91 9.8 2.5 10 6.5 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG37344.1 - 1.6 9.0 4.3 8.1 6.7 0.2 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 vATP-synt_AC39 PF01992.16 CEG37346.1 - 1.3e-97 327.3 0.0 1.5e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit tRNA-synt_1 PF00133.22 CEG37347.1 - 1e-66 225.5 1.6 1.3e-46 159.1 6.2 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CEG37347.1 - 2.1e-50 170.8 0.0 3.1e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CEG37347.1 - 3.7e-26 91.8 0.0 2.2e-20 72.8 0.0 3.7 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEG37347.1 - 5.8e-13 49.1 0.1 1e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CEG37347.1 - 0.026 13.9 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Dynein_light PF01221.18 CEG37349.1 - 3.2e-43 146.0 1.8 3.5e-43 145.8 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 zf-AN1 PF01428.16 CEG37350.1 - 4.6e-19 68.3 44.9 1.4e-12 47.5 10.2 4.9 4 1 1 5 5 5 2 AN1-like Zinc finger zf-C2H2_4 PF13894.6 CEG37350.1 - 0.0019 18.8 2.0 0.11 13.3 0.4 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG37350.1 - 0.0027 18.0 0.9 0.11 13.0 0.2 5.2 6 0 0 6 6 6 2 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 CEG37350.1 - 0.0052 16.6 1.0 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-WRNIP1_ubi PF18279.1 CEG37350.1 - 0.025 15.2 1.8 0.025 15.2 1.8 4.7 4 1 0 4 4 4 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 CEG37350.1 - 0.088 13.3 10.1 3.5 8.2 0.1 4.1 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 CEG37350.1 - 0.1 12.6 0.0 0.1 12.6 0.0 4.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CEG37350.1 - 0.41 10.5 6.7 1.2 9.0 0.3 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) NUDE_C PF04880.13 CEG37350.1 - 0.76 10.2 7.1 0.56 10.7 2.8 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Transp_Tc5_C PF04236.15 CEG37350.1 - 1.5 9.2 30.2 2.2 8.7 6.2 3.8 3 1 1 4 4 4 0 Tc5 transposase C-terminal domain Ribosomal_L35p PF01632.19 CEG37351.1 - 0.00029 21.3 7.1 0.055 14.0 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L35 PCP_red PF08369.10 CEG37351.1 - 0.085 13.1 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit G6PD_C PF02781.16 CEG37353.1 - 2.5e-33 115.5 0.1 4.8e-33 114.6 0.1 1.4 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEG37353.1 - 5.9e-22 79.1 1.1 1e-21 78.4 0.1 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Aa_trans PF01490.18 CEG37354.1 - 1.9e-09 36.7 28.5 6.9e-09 34.9 28.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L27e PF01777.18 CEG37355.1 - 4.8e-27 94.1 3.3 6.9e-27 93.6 3.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CEG37355.1 - 0.00091 19.1 1.6 0.00091 19.1 1.6 2.2 3 0 0 3 3 3 1 KOW motif DENN PF02141.21 CEG37356.1 - 2.4e-51 174.4 4.7 4.7e-51 173.4 4.7 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain ArfGap PF01412.18 CEG37356.1 - 1.5e-29 102.4 0.1 3.8e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3490 PF11995.8 CEG37356.1 - 1.1e-10 41.6 3.8 9.9e-06 25.5 0.6 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF3490) uDENN PF03456.18 CEG37356.1 - 1.5e-09 38.5 0.1 3.8e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CEG37356.1 - 2e-09 37.3 3.4 6.5e-09 35.6 3.4 2.0 1 0 0 1 1 1 1 dDENN domain IQ PF00612.27 CEG37356.1 - 0.0003 20.3 29.6 0.022 14.5 1.6 6.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif SPRY PF00622.28 CEG37357.1 - 2.1e-08 34.3 0.0 3.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain XPG_N PF00752.17 CEG37362.1 - 7.6e-29 100.2 0.0 1.5e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEG37362.1 - 3.6e-27 94.5 0.0 8.3e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CEG37362.1 - 0.00047 20.7 0.0 0.0015 19.1 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 CEG37362.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Sld3_N PF18523.1 CEG37363.1 - 0.062 13.4 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Sld3 N-terminal domain Chromo PF00385.24 CEG37364.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rubis-subs-bind PF09273.11 CEG37367.1 - 4.6e-14 53.2 1.5 9.1e-14 52.3 1.5 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding FYVE_2 PF02318.16 CEG37368.1 - 0.12 12.6 8.4 0.37 11.0 8.1 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 CEG37368.1 - 0.13 12.4 2.2 0.44 10.7 2.2 1.9 1 0 0 1 1 1 0 B-box zinc finger RWP-RK PF02042.15 CEG37369.1 - 2.2e-13 50.0 0.0 5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 CEG37369.1 - 0.001 18.7 0.1 0.0056 16.3 0.1 1.8 1 1 1 2 2 2 2 Sigma-70, region 4 HTH_38 PF13936.6 CEG37369.1 - 0.016 14.9 0.4 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_50 PF18024.1 CEG37369.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 CEG37369.1 - 0.036 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TnsD PF15978.5 CEG37369.1 - 0.09 11.7 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D DUF4158 PF13700.6 CEG37369.1 - 0.091 12.6 0.1 0.2 11.5 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4158) HTH_17 PF12728.7 CEG37369.1 - 0.15 12.2 0.1 2.8 8.2 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain RWP-RK PF02042.15 CEG37370.1 - 1.7e-13 50.3 0.0 3.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 CEG37370.1 - 0.0001 21.9 0.0 0.0041 16.8 0.1 2.9 2 1 1 3 3 3 2 Sigma-70, region 4 HTH_50 PF18024.1 CEG37370.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 CEG37370.1 - 0.02 13.9 0.2 0.022 13.8 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_6 PF01418.17 CEG37370.1 - 0.033 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_38 PF13936.6 CEG37370.1 - 0.044 13.5 0.1 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ubiquitin PF00240.23 CEG37371.1 - 9.5e-06 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 CEG37371.1 - 0.024 14.6 0.0 2.4 8.3 0.0 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 CEG37371.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_M24 PF00557.24 CEG37372.1 - 9.8e-41 139.7 0.0 1.7e-40 139.0 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 bZIP_1 PF00170.21 CEG37373.1 - 0.0064 16.6 0.3 0.0064 16.6 0.3 21.8 23 3 2 25 25 25 4 bZIP transcription factor IKKbetaNEMObind PF12179.8 CEG37373.1 - 0.9 9.6 8.2 8.8 6.5 1.0 4.6 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain Ribosomal_S5_C PF03719.15 CEG37374.1 - 4.1e-21 74.2 0.0 1.2e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CEG37374.1 - 5.1e-18 64.8 0.4 1.1e-17 63.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Arf PF00025.21 CEG37375.1 - 2.6e-44 150.7 0.0 3.2e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CEG37375.1 - 6.5e-13 48.6 0.0 9.1e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG37375.1 - 2.3e-12 47.2 0.0 4.4e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEG37375.1 - 2.4e-10 40.2 0.0 3.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEG37375.1 - 3.8e-10 39.4 0.1 3.4e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CEG37375.1 - 9.2e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEG37375.1 - 9e-06 25.2 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEG37375.1 - 1.3e-05 24.8 0.1 0.014 14.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CEG37375.1 - 0.00079 19.3 0.0 0.008 16.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CEG37375.1 - 0.0051 16.7 0.1 0.095 12.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CEG37375.1 - 0.013 15.2 0.1 6.7 6.5 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CEG37375.1 - 0.018 15.5 0.0 6.9 7.0 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEG37375.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEG37375.1 - 0.048 14.2 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEG37375.1 - 0.088 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CEG37375.1 - 0.16 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DLIC PF05783.11 CEG37375.1 - 0.21 10.4 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ubiquitin PF00240.23 CEG37376.1 - 1.4e-25 88.8 0.7 1.5e-25 88.7 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG37376.1 - 6.3e-14 51.6 0.7 6.9e-14 51.4 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CEG37376.1 - 7.8e-06 26.0 0.1 1.8e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CEG37376.1 - 1.6e-05 25.2 0.2 1.7e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CEG37376.1 - 7.5e-05 23.1 0.1 0.00028 21.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CEG37376.1 - 0.0036 17.8 0.0 0.0042 17.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Blt1 PF12754.7 CEG37376.1 - 0.085 13.2 0.0 0.087 13.1 0.0 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain Peptidase_C12 PF01088.21 CEG37377.1 - 1.5e-70 237.3 0.0 2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CEG37377.1 - 1.3e-19 69.8 1.6 1.3e-19 69.8 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases DUF3203 PF11462.8 CEG37377.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) ABC_tran PF00005.27 CEG37378.1 - 9.5e-55 184.9 0.0 6.4e-28 98.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CEG37378.1 - 4.5e-29 101.6 40.0 6.7e-17 61.6 9.5 3.8 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CEG37378.1 - 3.8e-18 66.3 2.2 7e-06 26.1 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEG37378.1 - 4.8e-05 23.9 0.6 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CEG37378.1 - 0.00019 20.9 0.0 3.5 7.0 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG37378.1 - 0.00021 20.9 1.1 0.056 13.2 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CEG37378.1 - 0.00047 20.3 0.0 2.3 8.5 0.0 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CEG37378.1 - 0.0015 18.5 0.1 0.076 12.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 CEG37378.1 - 0.0018 18.1 0.1 0.095 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 CEG37378.1 - 0.0086 15.8 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 CEG37378.1 - 0.038 13.8 1.1 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.6 CEG37378.1 - 0.046 14.1 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 CEG37378.1 - 0.057 12.7 0.1 6.9 5.9 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 CEG37378.1 - 0.086 13.1 0.5 6.7 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CEG37378.1 - 1 9.0 6.0 6.4 6.3 0.2 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Wzy_C PF04932.15 CEG37379.1 - 0.047 13.3 0.2 0.066 12.8 0.2 1.2 1 0 0 1 1 1 0 O-Antigen ligase Spore_GerAC PF05504.11 CEG37381.1 - 0.063 13.5 0.1 0.095 12.9 0.1 1.3 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Peptidase_A3 PF02160.15 CEG37381.1 - 0.23 10.9 2.5 0.28 10.7 2.5 1.1 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) HAUS6_N PF14661.6 CEG37381.1 - 0.46 10.0 7.1 0.58 9.7 7.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Abhydrolase_1 PF00561.20 CEG37382.1 - 5e-13 49.3 0.0 1.1e-10 41.6 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG37382.1 - 3.4e-05 23.2 0.0 7e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CEG37382.1 - 4e-05 23.1 0.1 5.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Malic_M PF03949.15 CEG37383.1 - 1.3e-93 313.0 0.0 1.8e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEG37383.1 - 5.2e-72 241.5 0.0 7.9e-72 240.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NAD_Gly3P_dh_N PF01210.23 CEG37383.1 - 0.029 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tubulin PF00091.25 CEG37384.1 - 1.9e-62 211.0 0.0 3.1e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG37384.1 - 3e-29 101.7 0.1 6.8e-29 100.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CEG37384.1 - 0.00068 18.9 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 CEG37384.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Suv3_N PF18114.1 CEG37385.1 - 0.05 13.7 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Rab3-GTPase_cat PF13890.6 CEG37388.1 - 1.9e-55 187.0 0.2 3.7e-55 186.0 0.2 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit gag_pre-integrs PF13976.6 CEG37391.1 - 3.3e-06 26.9 0.1 8e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 CEG37391.1 - 0.00051 20.2 0.1 0.001 19.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain CMV_US PF08001.11 CEG37391.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 CMV US RVT_2 PF07727.14 CEG37394.1 - 7.3e-31 107.7 0.1 9e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydantoinase_B PF02538.14 CEG37397.1 - 2.2e-213 709.4 0.2 3.7e-213 708.6 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CEG37397.1 - 6.1e-99 330.9 0.1 1e-98 330.2 0.1 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CEG37397.1 - 7.9e-58 195.1 1.1 1.1e-55 188.1 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region zf-CCHC_4 PF14392.6 CEG37398.1 - 8.5e-06 25.4 8.7 0.00023 20.8 1.1 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CEG37398.1 - 9.1e-05 22.4 17.4 0.005 16.9 2.1 2.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 CEG37398.1 - 0.036 13.9 7.0 0.32 10.8 1.6 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEG37398.1 - 0.04 13.9 4.1 0.87 9.6 0.6 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.6 CEG37398.1 - 0.064 12.7 3.0 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CEG37398.1 - 0.09 12.5 2.8 5.6 6.8 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CEG37398.1 - 0.62 10.1 6.0 0.43 10.6 4.1 1.7 2 0 0 2 2 2 0 Double zinc ribbon Rubredoxin_2 PF18073.1 CEG37398.1 - 3.6 7.4 6.6 11 5.9 0.2 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain CLIP1_ZNF PF16641.5 CEG37398.1 - 5.7 6.9 7.1 14 5.7 0.3 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle CAF1 PF04857.20 CEG37399.1 - 2e-19 69.9 3.7 4.8e-12 45.7 0.0 2.8 2 1 0 2 2 2 2 CAF1 family ribonuclease SRPRB PF09439.10 CEG37400.1 - 3.7e-32 111.2 0.0 5.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CEG37400.1 - 4.3e-14 52.3 0.0 6.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CEG37400.1 - 2e-07 30.7 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG37400.1 - 9.2e-07 29.1 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CEG37400.1 - 4.2e-05 23.0 0.0 5.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG37400.1 - 6.2e-05 23.1 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG37400.1 - 0.0017 17.9 0.3 0.0051 16.4 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CEG37400.1 - 0.0084 15.3 0.1 0.72 8.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 CEG37400.1 - 0.054 13.5 0.0 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 Dynamin family RPA_interact_M PF14767.6 CEG37400.1 - 0.07 13.7 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting middle ATP_bind_1 PF03029.17 CEG37400.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 CEG37400.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain HMA PF00403.26 CEG37403.1 - 1.5e-05 25.3 0.1 0.0004 20.8 0.0 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain PUB PF09409.10 CEG37405.1 - 4.3e-12 45.8 0.1 1.5e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 PUB domain Transglut_core PF01841.19 CEG37405.1 - 1.4e-11 44.8 0.3 3.7e-11 43.5 0.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CEG37405.1 - 8.5e-10 38.5 0.7 1.8e-09 37.4 0.7 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain AZUL PF16558.5 CEG37405.1 - 0.00017 21.7 0.8 0.00067 19.8 0.8 2.1 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PAW PF04721.17 CEG37405.1 - 0.056 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Jacalin PF01419.17 CEG37405.1 - 0.08 12.9 0.2 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Jacalin-like lectin domain Ras PF00071.22 CEG37406.1 - 4e-43 146.8 0.0 4.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG37406.1 - 6.7e-12 45.7 0.0 9.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CEG37406.1 - 2.1e-05 24.5 0.0 0.093 12.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG37406.1 - 4.9e-05 23.4 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG37406.1 - 0.001 18.6 0.0 0.004 16.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEG37406.1 - 0.0084 15.7 0.6 0.58 9.7 0.6 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG37406.1 - 0.031 14.7 0.0 0.035 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CEG37406.1 - 0.13 11.2 0.0 6.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Gp_dh_C PF02800.20 CEG37407.1 - 2.8e-66 222.0 0.0 3.9e-66 221.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEG37407.1 - 1.1e-39 134.8 0.1 1.5e-38 131.2 0.0 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CEG37407.1 - 0.0047 17.0 0.1 0.019 15.1 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus LRR_4 PF12799.7 CEG37408.1 - 3.5e-07 30.4 8.4 0.15 12.5 0.1 6.4 5 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG37408.1 - 1.1e-06 28.2 8.3 3.6 7.9 0.1 7.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 CEG37408.1 - 0.00094 18.9 2.9 0.01 15.6 0.9 3.8 4 0 0 4 4 4 1 Leucine rich repeat DUF2957 PF11170.8 CEG37408.1 - 0.12 11.2 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2957) Myb_DNA-binding PF00249.31 CEG37409.1 - 1.6e-41 140.2 16.9 5.4e-15 55.3 0.8 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG37409.1 - 3.4e-35 120.1 6.3 7.9e-16 58.1 0.5 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEG37409.1 - 7.2e-07 29.2 0.0 0.11 12.5 0.0 3.4 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 CEG37409.1 - 1.1e-05 25.2 2.3 0.62 10.0 0.1 3.4 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEG37409.1 - 0.0002 21.5 0.2 0.13 12.5 0.1 2.6 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 CEG37409.1 - 0.0066 16.7 9.3 0.53 10.6 0.6 3.5 2 1 1 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 CEG37409.1 - 0.022 14.8 0.2 0.62 10.2 0.1 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 CEG37409.1 - 0.025 14.7 0.1 0.06 13.5 0.1 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 CEG37409.1 - 3.3 8.2 12.1 2.8 8.4 0.5 3.4 1 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Acyl_transf_3 PF01757.22 CEG37410.1 - 1.6e-15 57.0 37.3 2.1e-15 56.7 37.3 1.1 1 0 0 1 1 1 1 Acyltransferase family Oxidored_q2 PF00420.24 CEG37410.1 - 0.19 11.4 2.8 0.71 9.5 0.2 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cadherin_C_2 PF16492.5 CEG37410.1 - 1.3 9.9 4.9 13 6.6 0.0 3.4 3 1 1 4 4 4 0 Cadherin cytoplasmic C-terminal LRR_9 PF14580.6 CEG37412.1 - 4.9e-12 45.7 9.4 3.5e-09 36.4 0.6 3.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 CEG37412.1 - 6.6e-08 32.7 33.2 4.4e-05 23.8 8.3 5.1 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG37412.1 - 5e-05 23.0 20.0 0.0048 16.6 9.0 3.8 2 1 2 4 4 4 3 Leucine rich repeat Dip PF17679.1 CEG37412.1 - 0.0016 18.1 0.1 0.0038 16.9 0.1 1.6 1 0 0 1 1 1 1 gp37/Dip protein TipAS PF07739.13 CEG37412.1 - 0.069 13.7 0.1 0.069 13.7 0.1 2.9 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Musclin PF11037.8 CEG37412.1 - 0.29 11.0 3.6 0.36 10.7 0.5 2.4 1 1 1 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle HUN PF08729.10 CEG37413.1 - 1.6e-12 47.2 6.4 3.4e-12 46.2 6.1 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.6 CEG37413.1 - 0.00051 19.8 0.8 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 1 Ubinuclein conserved middle domain XPG_I PF00867.18 CEG37417.1 - 8.1e-21 74.2 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEG37417.1 - 2e-18 66.7 0.0 4.2e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEG37417.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 CEG37417.1 - 0.03 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DNA_pol_phi PF04931.13 CEG37419.1 - 4.8e-84 282.9 40.5 4e-81 273.3 25.8 3.6 2 1 1 3 3 3 2 DNA polymerase phi HEAT_EZ PF13513.6 CEG37419.1 - 0.015 15.8 1.6 9.9 6.8 0.2 3.6 2 0 0 2 2 2 0 HEAT-like repeat PMT2_N PF17987.1 CEG37419.1 - 0.034 14.3 3.2 1.1 9.5 0.0 3.5 3 0 0 3 3 3 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Nop52 PF05997.12 CEG37419.1 - 1.5 8.6 7.4 0.35 10.6 0.3 3.6 4 0 0 4 4 4 0 Nucleolar protein,Nop52 Sec61_beta PF03911.16 CEG37420.1 - 4.6e-19 68.2 0.1 6e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family DUF591 PF04569.14 CEG37420.1 - 0.24 11.5 5.8 1 9.5 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function LRR_4 PF12799.7 CEG37421.1 - 6.3e-05 23.3 8.4 0.056 13.9 0.5 3.6 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG37421.1 - 0.00014 21.6 8.7 0.09 12.6 1.3 3.9 2 2 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CEG37421.1 - 0.073 12.6 1.1 0.42 10.1 1.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Fe-ADH PF00465.19 CEG37421.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase LRR_5 PF13306.6 CEG37421.1 - 0.095 12.7 4.4 0.11 12.5 2.4 1.8 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Haemagg_act PF05860.13 CEG37421.1 - 2.3 8.1 8.3 7.7 6.4 1.6 2.8 2 1 1 3 3 3 0 haemagglutination activity domain Tam41_Mmp37 PF09139.11 CEG37422.1 - 1.2e-100 337.1 1.5 1.5e-100 336.8 1.5 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Ribosomal_L32e PF01655.18 CEG37422.1 - 0.089 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L32 RICTOR_N PF14664.6 CEG37423.1 - 0.0025 16.8 0.4 1.9 7.4 0.0 3.1 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term DUF3361 PF11841.8 CEG37423.1 - 0.01 15.8 0.1 4.9 7.1 0.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) DUF2312 PF10073.9 CEG37423.1 - 0.038 13.6 0.7 0.12 12.1 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3834 PF12916.7 CEG37423.1 - 0.043 13.1 0.0 0.092 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3834) Alkyl_sulf_dimr PF14863.6 CEG37423.1 - 0.08 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation HEAT_2 PF13646.6 CEG37423.1 - 0.22 12.0 1.8 14 6.1 0.0 3.5 3 1 2 5 5 5 0 HEAT repeats Fes1 PF08609.10 CEG37423.1 - 0.99 10.3 4.7 0.89 10.5 1.6 2.6 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 SCO1-SenC PF02630.14 CEG37426.1 - 1.2e-28 99.7 0.1 1.4e-27 96.2 0.1 2.1 1 1 1 2 2 2 2 SCO1/SenC Thioredoxin_8 PF13905.6 CEG37426.1 - 0.0078 16.5 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CEG37426.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family NatB_MDM20 PF09797.9 CEG37427.1 - 3.2e-57 194.2 7.7 3.2e-57 194.2 7.7 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit AbiJ_NTD5 PF18865.1 CEG37427.1 - 1.7 8.5 5.5 22 4.9 0.2 3.7 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 WD40 PF00400.32 CEG37428.1 - 1.6e-15 57.2 7.8 0.00058 20.6 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CEG37428.1 - 4.3e-12 45.5 12.6 8.2e-12 44.6 12.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 CEG37428.1 - 2.9e-05 24.3 6.8 2.9e-05 24.3 6.8 2.5 1 1 1 2 2 2 1 Zinc-ribbon like family rRNA_processing PF08524.11 CEG37429.1 - 3e-11 43.5 25.6 2.6e-10 40.5 25.6 2.0 1 1 0 1 1 1 1 rRNA processing TRAF_BIRC3_bd PF16673.5 CEG37429.1 - 6.6 6.6 13.6 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain PP-binding PF00550.25 CEG37430.1 - 1.1e-11 44.9 0.1 1.4e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CEG37430.1 - 6.5e-05 23.1 0.4 8.5e-05 22.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier ATG16 PF08614.11 CEG37431.1 - 4.9 7.3 36.3 9.2 6.4 15.6 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CEG37431.1 - 7.8 6.9 31.0 1.9 8.9 23.5 2.2 1 1 0 2 2 2 0 Fez1 Prefoldin_2 PF01920.20 CEG37432.1 - 6e-22 77.6 5.4 6.8e-22 77.4 5.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 CEG37432.1 - 0.00019 21.5 1.3 0.00061 19.8 0.4 1.9 2 0 0 2 2 2 1 DASH complex subunit Dad3 Prefoldin PF02996.17 CEG37432.1 - 0.00057 19.8 3.1 0.081 12.8 0.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit ZapB PF06005.12 CEG37432.1 - 0.0058 17.1 0.9 0.0058 17.1 0.9 2.1 2 0 0 2 2 2 1 Cell division protein ZapB DUF4201 PF13870.6 CEG37432.1 - 0.0064 16.2 3.9 0.24 11.1 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) DUF1488 PF07369.11 CEG37432.1 - 0.012 15.6 0.2 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) CCDC24 PF15669.5 CEG37432.1 - 0.014 15.3 1.7 0.052 13.4 1.7 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DivIVA PF05103.13 CEG37432.1 - 0.044 13.9 5.8 0.14 12.2 1.9 2.0 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.15 CEG37432.1 - 0.071 12.9 0.8 0.071 12.9 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.13 CEG37432.1 - 0.079 13.7 2.0 1 10.1 0.1 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF4795 PF16043.5 CEG37432.1 - 0.096 12.3 2.6 2 7.9 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) PhoU PF01895.19 CEG37432.1 - 0.15 12.5 1.2 5 7.7 0.3 2.1 1 1 1 2 2 2 0 PhoU domain TPR_MLP1_2 PF07926.12 CEG37432.1 - 0.24 11.5 9.7 1.4 9.0 1.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 CEG37432.1 - 0.32 11.3 6.4 0.4 11.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 CEG37432.1 - 0.47 10.7 8.7 0.36 11.0 2.5 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CEG37432.1 - 1 9.9 9.2 3.5 8.1 2.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 CEG37432.1 - 1.2 9.0 6.5 0.19 11.6 1.7 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 CEG37432.1 - 6.1 7.5 10.7 2.9 8.6 3.1 2.6 2 1 0 2 2 2 0 SlyX Ribosomal_S21e PF01249.18 CEG37433.1 - 5.2e-35 119.4 0.1 6.1e-35 119.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e zf-Tim10_DDP PF02953.15 CEG37434.1 - 8.3e-19 67.0 3.2 1e-18 66.7 3.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Toxin_13 PF07822.11 CEG37434.1 - 0.015 15.4 0.4 0.022 14.9 0.4 1.2 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Cmc1 PF08583.10 CEG37437.1 - 6.4e-11 42.1 2.5 8.5e-11 41.7 2.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CEG37437.1 - 0.00029 20.9 1.6 0.0004 20.4 1.6 1.2 1 0 0 1 1 1 1 CHCH domain Ubiq_cyt_C_chap PF03981.12 CEG37438.1 - 7.4e-23 81.2 0.1 1.1e-22 80.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 CEG37438.1 - 4.4e-05 23.5 0.5 8.1e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 WW domain Sas10 PF09368.10 CEG37439.1 - 3.3e-25 88.3 11.1 1e-24 86.8 11.1 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CEG37439.1 - 1.2e-09 38.7 2.9 1.2e-09 38.7 2.9 2.8 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Rep_4 PF05797.11 CEG37439.1 - 0.25 10.4 7.7 0.58 9.2 7.7 1.6 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) ETC_C1_NDUFA5 PF04716.14 CEG37440.1 - 1e-24 86.1 0.3 1.7e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region LSM PF01423.22 CEG37441.1 - 5.2e-15 54.9 1.3 5.8e-15 54.7 0.4 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 CEG37441.1 - 0.043 13.5 0.1 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein CHCH PF06747.13 CEG37442.1 - 2.7 8.3 6.8 4 7.7 0.1 2.8 3 0 0 3 3 3 0 CHCH domain YceG PF02618.16 CEG37443.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 YceG-like family WXG100 PF06013.12 CEG37444.1 - 0.91 9.8 4.5 1.7 9.0 0.0 3.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG TPR_16 PF13432.6 CEG37444.1 - 3.7 8.3 8.0 5.7 7.7 2.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 CEG37444.1 - 5.9 7.4 10.6 2 9.0 6.0 2.2 1 1 0 2 2 2 0 Apg6 coiled-coil region PTEN_C2 PF10409.9 CEG37447.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 CEG37447.1 - 3.1e-05 23.7 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG37447.1 - 0.00047 20.0 0.1 0.00077 19.3 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEG37447.1 - 0.00078 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CEG37447.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CEG37447.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CEG37447.1 - 0.035 14.2 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate EF-hand_6 PF13405.6 CEG37448.1 - 1.3e-10 40.4 2.9 0.066 13.2 0.1 6.7 8 0 0 8 8 8 3 EF-hand domain EF-hand_7 PF13499.6 CEG37448.1 - 2.4e-10 40.7 2.8 0.024 15.1 0.0 6.1 5 2 1 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 CEG37448.1 - 3.8e-09 35.4 0.2 0.092 12.3 0.1 5.9 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 CEG37448.1 - 0.00011 22.0 2.5 0.27 11.1 0.0 5.4 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG37448.1 - 0.0003 20.2 0.5 0.49 10.0 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CEG37448.1 - 0.042 14.2 0.0 25 5.3 0.0 3.8 3 0 0 3 3 3 0 EF-hand domain Gtr1_RagA PF04670.12 CEG37449.1 - 9.9e-70 234.5 0.9 1.2e-69 234.2 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CEG37449.1 - 4.1e-05 23.1 0.0 0.00013 21.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEG37449.1 - 5.5e-05 22.7 0.0 9.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG37449.1 - 0.00099 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CEG37449.1 - 0.0019 18.4 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CEG37449.1 - 0.016 15.6 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CEG37449.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sulfate_transp PF00916.20 CEG37450.1 - 9.4e-23 80.6 28.7 1.5e-22 79.9 28.7 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CEG37450.1 - 1.1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CEG37450.1 - 2.1e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain Thioredoxin_10 PF17991.1 CEG37451.1 - 0.13 12.8 0.1 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Bcr-Abl_Oligo PF09036.10 CEG37451.1 - 0.31 11.1 2.2 0.76 9.8 0.2 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Borrelia_REV PF03978.13 CEG37451.1 - 1.8 8.5 7.5 3.3 7.6 7.5 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Atg14 PF10186.9 CEG37451.1 - 9 5.3 12.7 15 4.5 12.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 CEG37452.1 - 2.1e-19 69.9 0.9 3.3e-14 53.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG37452.1 - 1.7e-18 66.5 0.5 1.6e-09 37.8 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG37452.1 - 5.5e-17 61.9 0.0 5.2e-08 33.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG37452.1 - 5e-16 58.3 0.1 4.2e-05 23.8 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CEG37452.1 - 8.5e-12 44.2 0.0 8.9e-05 22.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Pfk_N PF18468.1 CEG37452.1 - 0.2 12.1 0.0 3.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast Peptidase_C13 PF01650.18 CEG37453.1 - 6.9e-101 337.1 0.6 9.8e-101 336.6 0.6 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF3943 PF13084.6 CEG37453.1 - 0.033 14.0 0.3 0.36 10.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3943) bZIP_1 PF00170.21 CEG37455.1 - 0.015 15.3 3.6 0.015 15.3 3.6 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF2672 PF10878.8 CEG37455.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Pkip-1 PF06878.11 CEG37455.1 - 0.081 13.0 4.6 0.3 11.2 0.5 2.8 2 1 1 3 3 3 0 Pkip-1 protein HR1 PF02185.16 CEG37455.1 - 1.8 8.7 8.2 1.9 8.7 2.7 2.5 2 0 0 2 2 2 0 Hr1 repeat zf-RanBP PF00641.18 CEG37456.1 - 2.6e-15 55.4 22.4 3.4e-08 32.7 5.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Transformer PF06495.11 CEG37456.1 - 0.28 11.2 21.2 0.55 10.3 21.2 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Prim_Zn_Ribbon PF08273.12 CEG37456.1 - 0.39 11.0 17.1 3.3 8.1 4.8 4.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF35_N PF12172.8 CEG37456.1 - 1.8 8.6 8.8 0.7 9.8 0.8 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NopRA1 PF16201.5 CEG37457.1 - 2.1e-50 171.1 1.2 2.1e-50 171.1 1.2 2.7 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 TAL_effector PF03377.13 CEG37457.1 - 0.0017 18.6 0.2 0.12 12.7 0.0 2.8 2 0 0 2 2 2 1 TAL effector repeat RTP1_C1 PF10363.9 CEG37457.1 - 0.0049 17.0 1.6 4.8 7.4 0.0 4.2 3 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 EF-hand_7 PF13499.6 CEG37458.1 - 3.2e-10 40.3 1.8 1.4e-09 38.3 1.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair IQ PF00612.27 CEG37458.1 - 2.2e-09 36.3 43.8 0.0045 16.7 1.0 8.9 8 0 0 8 8 8 4 IQ calmodulin-binding motif EF-hand_6 PF13405.6 CEG37458.1 - 1.5e-08 33.9 1.3 0.00046 19.9 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEG37458.1 - 6.1e-08 31.7 1.0 0.00018 20.8 0.2 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG37458.1 - 7e-08 32.2 0.8 0.0026 17.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG37458.1 - 7.1e-06 25.3 0.5 0.029 13.8 0.1 2.9 2 0 0 2 2 2 2 EF hand DUF2738 PF10927.8 CEG37460.1 - 0.18 10.9 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) CCT PF06203.14 CEG37461.1 - 1.7e-16 60.0 14.3 4.1e-16 58.8 14.3 1.7 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 CEG37461.1 - 0.071 13.0 4.3 0.18 11.7 4.3 1.7 1 0 0 1 1 1 0 Divergent CCT motif dsrm PF00035.26 CEG37463.1 - 3.8e-06 27.5 0.0 8.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif CLZ PF16526.5 CEG37463.1 - 0.36 11.2 10.3 11 6.4 3.4 4.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMEM138 PF14935.6 CEG37464.1 - 2e-16 60.7 4.7 2.8e-16 60.2 4.7 1.2 1 0 0 1 1 1 1 Transmembrane protein 138 DAD PF02109.16 CEG37464.1 - 0.25 11.7 5.6 14 6.0 4.1 2.4 1 1 1 2 2 2 0 DAD family zf-C2H2 PF00096.26 CEG37466.1 - 8.1e-20 70.1 23.9 3.3e-05 24.1 0.6 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG37466.1 - 3e-13 49.4 20.4 0.0079 17.0 0.4 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEG37466.1 - 2e-11 43.8 27.2 1.2e-06 28.7 1.3 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEG37466.1 - 1.3e-05 25.4 9.5 0.0019 18.5 4.8 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CEG37466.1 - 6.1e-05 22.9 13.0 0.92 9.6 0.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEG37466.1 - 0.00059 20.0 7.7 3.9 7.6 0.4 4.1 1 1 3 4 4 4 2 Aberrant zinc-finger zf_Hakai PF18408.1 CEG37466.1 - 0.0028 17.3 12.8 0.039 13.7 0.6 3.9 4 0 0 4 4 4 2 C2H2 Hakai zinc finger domain GAGA PF09237.11 CEG37466.1 - 0.0031 17.3 0.5 0.1 12.4 0.3 2.4 2 0 0 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.8 CEG37466.1 - 0.034 14.4 9.0 5.2 7.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEG37466.1 - 0.17 12.5 7.5 0.7 10.6 0.1 3.5 1 1 1 3 3 3 0 FOXP coiled-coil domain Sina PF03145.16 CEG37466.1 - 1.1 9.2 10.6 0.27 11.2 2.7 2.2 1 1 1 2 2 2 0 Seven in absentia protein family zf-H2C2_5 PF13909.6 CEG37466.1 - 1.4 8.7 0.0 1.4 8.7 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-DNA_Pol PF08996.10 CEG37466.1 - 1.8 8.2 7.6 2.2 8.0 1.5 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_11 PF16622.5 CEG37466.1 - 2.2 8.1 14.3 8.5 6.2 1.1 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 CEG37466.1 - 2.5 8.1 11.2 18 5.4 1.6 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TA0956 PF11513.8 CEG37467.1 - 0.061 13.6 0.0 0.062 13.5 0.0 1.1 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Lar_N PF09861.9 CEG37468.1 - 1.9e-11 43.5 0.0 6.4e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Lactate racemase N-terminal domain TTRAP PF14203.6 CEG37468.1 - 0.017 15.1 0.0 0.055 13.5 0.0 1.9 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Sedlin_N PF04628.13 CEG37471.1 - 1.6e-38 131.7 0.1 1.8e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CEG37471.1 - 3.3e-13 49.8 0.1 3.9e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family CCM2_C PF16545.5 CEG37471.1 - 0.093 13.3 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Ribosomal_S19e PF01090.19 CEG37472.1 - 7.8e-57 190.8 0.4 9.5e-57 190.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e ASCH PF04266.14 CEG37472.1 - 0.085 13.4 0.1 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 ASCH domain Nop PF01798.18 CEG37473.1 - 5.9e-86 287.7 0.4 1.2e-85 286.6 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CEG37473.1 - 6.3e-19 68.1 2.6 6.3e-19 68.1 2.6 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Csd3_N PF18059.1 CEG37473.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Csd3 N-terminal Coilin_N PF15862.5 CEG37473.1 - 0.89 9.4 7.5 1.7 8.5 7.5 1.4 1 0 0 1 1 1 0 Coilin N-terminus Acylphosphatase PF00708.18 CEG37474.1 - 3e-13 50.0 0.2 4e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 Acylphosphatase DUF2012 PF09430.10 CEG37475.1 - 5.9e-21 74.8 0.1 8.9e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CEG37475.1 - 0.00027 21.1 0.1 0.00044 20.5 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2846 PF11008.8 CEG37475.1 - 0.058 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) CarbopepD_reg_2 PF13715.6 CEG37475.1 - 0.094 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 CarboxypepD_reg-like domain PNP_UDP_1 PF01048.20 CEG37477.1 - 6.2e-36 123.8 0.0 6.8e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Abhydrolase_6 PF12697.7 CEG37478.1 - 6.5e-13 49.8 0.0 8.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEG37478.1 - 8.1e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fer2 PF00111.27 CEG37483.1 - 6.2e-12 45.3 0.3 8.7e-12 44.8 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain AAA_6 PF12774.7 CEG37484.1 - 9.9e-155 514.4 0.0 2.6e-152 506.5 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG37484.1 - 5.7e-134 447.2 12.2 5.7e-134 447.2 12.2 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG37484.1 - 2.9e-102 342.0 3.1 1.5e-101 339.7 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CEG37484.1 - 7.6e-97 323.7 2.3 2.7e-96 321.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CEG37484.1 - 4.3e-84 281.0 7.4 1.5e-83 279.3 0.0 3.6 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG37484.1 - 3.9e-81 270.9 0.5 1.4e-76 256.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG37484.1 - 2.6e-51 173.7 0.0 7.3e-51 172.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG37484.1 - 7.2e-49 164.8 0.0 4.1e-44 149.5 0.1 3.3 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CEG37484.1 - 4.2e-43 147.7 14.7 7.9e-43 146.8 14.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CEG37484.1 - 9.7e-30 103.3 0.9 7.6e-29 100.4 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CEG37484.1 - 4.9e-23 81.7 0.0 3.1e-06 27.2 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CEG37484.1 - 6.8e-17 61.5 2.0 2.7e-16 59.6 0.1 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 CEG37484.1 - 2.1e-07 31.4 1.9 0.035 14.5 0.0 5.4 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG37484.1 - 1.7e-06 28.3 4.9 0.078 13.3 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 CEG37484.1 - 9.6e-06 26.1 4.0 0.75 10.2 0.0 5.6 5 1 0 5 5 5 2 AAA ATPase domain T2SSE PF00437.20 CEG37484.1 - 8.4e-05 21.8 0.1 0.082 11.9 0.0 3.9 4 0 0 4 4 4 1 Type II/IV secretion system protein RNA_helicase PF00910.22 CEG37484.1 - 0.00014 22.2 3.7 2.6 8.5 0.0 5.0 5 0 0 5 5 3 1 RNA helicase DUF853 PF05872.12 CEG37484.1 - 0.00019 20.2 1.1 1.1 7.8 0.0 3.5 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) AAA_14 PF13173.6 CEG37484.1 - 0.0024 17.9 0.0 0.49 10.4 0.0 3.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CEG37484.1 - 0.0078 16.8 0.1 0.63 10.6 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 CEG37484.1 - 0.008 15.9 0.5 6.5 6.4 0.2 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CEG37484.1 - 0.0083 15.9 0.1 4.6 6.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG37484.1 - 0.0096 16.4 0.0 2.5 8.6 0.0 3.2 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.21 CEG37484.1 - 0.023 14.1 0.4 7.8 5.8 0.0 3.6 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 CEG37484.1 - 0.034 13.5 0.2 4.4 6.6 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 CEG37484.1 - 0.063 13.2 0.6 17 5.3 0.0 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain DUF87 PF01935.17 CEG37484.1 - 0.071 13.2 12.3 1.1 9.3 0.1 4.8 5 0 0 5 5 3 0 Helicase HerA, central domain ATPase PF06745.13 CEG37484.1 - 0.13 11.6 2.9 0.38 10.1 0.0 2.9 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 CEG37484.1 - 0.14 12.5 1.6 46 4.3 0.0 4.0 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 CEG37484.1 - 2.8 6.8 8.4 1.6 7.5 0.0 3.6 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 CEG37484.1 - 3.5 7.2 7.2 59 3.2 0.1 4.3 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF745 PF05335.13 CEG37484.1 - 9.6 5.9 19.3 1.3 8.7 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) AKNA PF12443.8 CEG37485.1 - 0.29 11.8 6.6 5.4 7.7 0.3 4.3 2 1 1 3 3 3 0 AT-hook-containing transcription factor HALZ PF02183.18 CEG37485.1 - 0.99 9.7 6.0 1.3 9.3 0.4 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper HrpA_pilin PF09589.10 CEG37485.1 - 1.3 9.8 5.3 1.2 9.9 2.1 2.8 2 0 0 2 2 2 0 HrpA pilus formation protein Peptidase_M41 PF01434.18 CEG37486.1 - 2.7e-17 63.2 0.6 4.8e-17 62.4 0.6 1.4 1 1 0 1 1 1 1 Peptidase family M41 HTH_WhiA PF02650.14 CEG37486.1 - 0.097 13.0 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 WhiA C-terminal HTH domain YebG PF07130.12 CEG37487.1 - 0.07 13.0 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 YebG protein Furin-like_2 PF15913.5 CEG37488.1 - 0.0074 16.4 6.3 0.022 14.9 6.2 1.7 1 1 0 1 1 1 1 Furin-like repeat, cysteine-rich MIT_LIKE_ACTX PF17556.2 CEG37488.1 - 0.056 14.0 1.3 0.056 14.0 1.3 2.3 1 1 1 2 2 2 0 MIT-like atracotoxin family Dickkopf_N PF04706.12 CEG37488.1 - 2.8 8.5 11.3 16 6.0 11.3 2.3 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PRORP PF16953.5 CEG37489.1 - 1.4e-09 37.8 13.9 5.1e-08 32.7 1.6 4.7 3 1 0 3 3 3 2 Protein-only RNase P PPR_long PF17177.4 CEG37489.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 CEG37489.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Sec7 PF01369.20 CEG37490.1 - 9.3e-65 217.7 0.0 2.2e-64 216.5 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEG37490.1 - 4.4e-44 150.2 0.8 4.4e-44 150.2 0.8 2.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CEG37490.1 - 1e-28 99.0 0.0 4.2e-27 93.8 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 CEG37490.1 - 2.5e-25 89.2 10.0 3.5e-24 85.4 4.1 3.9 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 CEG37490.1 - 0.0011 17.2 0.0 0.0042 15.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein HrpA_pilin PF09589.10 CEG37490.1 - 0.21 12.3 1.9 0.86 10.4 1.9 2.1 1 0 0 1 1 1 0 HrpA pilus formation protein Imm32 PF15566.6 CEG37491.1 - 0.018 14.8 0.1 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 32 Glyco_hydro_72 PF03198.14 CEG37491.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase DNA_topoisoIV PF00521.20 CEG37492.1 - 4.6e-113 378.3 0.0 6.8e-113 377.8 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CEG37492.1 - 3.5e-43 146.9 2.5 4.2e-43 146.7 0.9 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CEG37492.1 - 5.3e-18 65.1 0.2 9.7e-17 61.0 0.0 2.3 2 0 0 2 2 2 1 DNA gyrase B UQ_con PF00179.26 CEG37492.1 - 2.7e-12 46.5 0.0 5.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HATPase_c PF02518.26 CEG37492.1 - 1.2e-08 35.5 0.0 4.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CEG37492.1 - 3.9e-06 27.0 0.0 1.8e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Toprim domain LTD PF00932.19 CEG37493.1 - 1.7e-05 25.1 0.0 2.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lamin Tail Domain AcrZ PF10766.9 CEG37493.1 - 0.033 13.8 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ UBX PF00789.20 CEG37494.1 - 1.6e-11 44.3 0.0 1.7e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 UBX domain RMI2 PF16100.5 CEG37495.1 - 1.4e-20 73.4 0.0 1.7e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Thioredoxin PF00085.20 CEG37496.1 - 6.9e-55 183.4 0.0 1.3e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CEG37496.1 - 4.9e-09 36.6 0.2 0.0014 19.0 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG37496.1 - 2.3e-08 34.2 0.0 0.043 14.1 0.0 3.4 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CEG37496.1 - 5.9e-07 29.3 0.0 0.0056 16.4 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CEG37496.1 - 8.2e-06 25.9 0.1 0.062 13.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 CEG37496.1 - 1.4e-05 25.0 0.0 0.065 13.0 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein OST3_OST6 PF04756.13 CEG37496.1 - 7.1e-05 22.3 0.0 0.011 15.1 0.0 2.4 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CEG37496.1 - 0.00013 21.9 0.1 0.67 9.9 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.6 CEG37496.1 - 0.00014 21.8 0.0 0.081 13.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.10 CEG37496.1 - 0.0013 18.4 0.8 1.4 8.6 0.1 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 CEG37496.1 - 0.01 15.8 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 CEG37496.1 - 0.29 11.4 3.3 7 7.0 0.1 3.0 2 1 0 2 2 2 0 Glutaredoxin ThiS PF02597.20 CEG37497.1 - 8e-11 42.4 0.0 1.1e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family BRCA2 PF00634.18 CEG37499.1 - 0.0087 15.7 0.2 0.0087 15.7 0.2 1.6 2 0 0 2 2 2 1 BRCA2 repeat Golgin_A5 PF09787.9 CEG37500.1 - 8.2e-06 25.5 16.3 8.2e-06 25.5 16.3 3.2 1 1 1 3 3 3 2 Golgin subfamily A member 5 YnfE PF17452.2 CEG37500.1 - 0.024 14.9 1.1 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized YnfE-like Thiamine_BP PF01910.17 CEG37500.1 - 0.049 13.6 0.1 0.2 11.6 0.1 2.1 1 0 0 1 1 1 0 Thiamine-binding protein DUF1192 PF06698.11 CEG37500.1 - 0.087 12.9 6.6 1.5 9.0 0.3 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) COG2 PF06148.11 CEG37500.1 - 0.23 11.5 27.8 0.058 13.5 5.1 4.6 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 CEG37500.1 - 4.9 5.9 50.4 0.25 10.2 10.5 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein IFT57 PF10498.9 CEG37500.1 - 9.7 5.0 38.5 0.19 10.7 5.2 3.5 2 2 2 4 4 4 0 Intra-flagellar transport protein 57 DEAD PF00270.29 CEG37502.1 - 5e-38 130.6 0.1 1.6e-37 129.0 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG37502.1 - 2.3e-26 92.3 0.3 4.3e-25 88.2 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG37502.1 - 5.7e-07 29.7 0.8 1.8e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flagellin_N PF00669.20 CEG37502.1 - 0.06 13.5 3.9 0.17 12.0 3.9 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region AAA_25 PF13481.6 CEG37503.1 - 4.4e-23 81.9 0.0 9.3e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 CEG37503.1 - 1e-11 45.1 0.0 4.2e-11 43.1 0.0 2.1 2 0 0 2 2 1 1 Toprim-like DnaB_C PF03796.15 CEG37503.1 - 9.1e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CEG37503.1 - 2.7e-08 34.2 0.0 8e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Toprim_3 PF13362.6 CEG37503.1 - 1.1e-07 32.1 0.0 5.9e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Toprim domain AAA_16 PF13191.6 CEG37503.1 - 6.7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Toprim_4 PF13662.6 CEG37503.1 - 2.4e-05 24.7 0.0 0.00019 21.9 0.0 2.3 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 CEG37503.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 KaiC zf-CHC2 PF01807.20 CEG37503.1 - 0.00054 19.7 0.4 0.0012 18.6 0.4 1.5 1 0 0 1 1 1 1 CHC2 zinc finger ABC_tran PF00005.27 CEG37503.1 - 0.00071 20.1 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 CEG37503.1 - 0.004 17.7 0.2 0.0089 16.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEG37503.1 - 0.0045 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.6 CEG37503.1 - 0.0057 16.4 0.1 0.021 14.6 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG37503.1 - 0.0067 16.3 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 1 1 RsgA GTPase PRK PF00485.18 CEG37503.1 - 0.0069 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CEG37503.1 - 0.01 16.1 0.6 0.026 14.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEG37503.1 - 0.013 15.5 0.2 0.054 13.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEG37503.1 - 0.014 15.4 0.1 0.037 13.9 0.1 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain cobW PF02492.19 CEG37503.1 - 0.014 15.0 0.5 0.034 13.7 0.2 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CEG37503.1 - 0.018 15.0 0.0 0.058 13.3 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CEG37503.1 - 0.019 14.9 0.2 0.045 13.7 0.2 1.6 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CEG37503.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CEG37503.1 - 0.026 14.9 0.1 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 RNA helicase Toprim PF01751.22 CEG37503.1 - 0.037 14.2 0.0 0.22 11.7 0.0 2.3 2 1 0 2 2 1 0 Toprim domain NTPase_1 PF03266.15 CEG37503.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 CEG37503.1 - 0.072 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 CEG37503.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lar_restr_allev PF14354.6 CEG37503.1 - 0.086 13.2 0.4 0.3 11.5 0.4 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar AAA_18 PF13238.6 CEG37503.1 - 0.088 13.3 0.1 0.32 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CEG37503.1 - 0.099 12.6 0.1 0.36 10.8 0.1 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 CEG37503.1 - 0.12 11.6 0.2 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.6 CEG37503.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zn_Tnp_IS1595 PF12760.7 CEG37503.1 - 0.32 11.0 1.4 0.8 9.7 1.4 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_2 PF13696.6 CEG37503.1 - 4.3 7.2 6.5 0.8 9.6 1.6 2.2 2 0 0 2 2 2 0 Zinc knuckle PriA_CRR PF18319.1 CEG37503.1 - 4.9 7.2 8.5 0.15 12.1 1.5 2.0 2 0 0 2 2 1 0 PriA DNA helicase Cys-rich region (CRR) domain Mito_carr PF00153.27 CEG37504.1 - 6.3e-52 173.5 3.2 7.1e-20 70.7 0.3 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEG37504.1 - 0.00023 20.4 1.4 0.35 10.0 0.2 3.3 3 1 0 3 3 3 2 Gammaproteobacterial serine protease TMEM234 PF10639.9 CEG37506.1 - 1.3e-35 121.9 0.5 2.5e-35 121.0 0.5 1.4 1 0 0 1 1 1 1 Putative transmembrane family 234 BCNT PF07572.12 CEG37506.1 - 1e-23 83.2 5.0 2.2e-23 82.1 5.0 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development EamA PF00892.20 CEG37506.1 - 0.0067 16.6 1.0 0.014 15.6 0.5 1.7 2 0 0 2 2 2 1 EamA-like transporter family Hist_deacetyl PF00850.19 CEG37507.1 - 1.5e-83 280.9 0.0 2.1e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF1295 PF06966.12 CEG37508.1 - 2.5e-17 63.2 0.1 3.1e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) RrnaAD PF00398.20 CEG37509.1 - 4.2e-05 22.8 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEG37509.1 - 0.042 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Hamartin PF04388.12 CEG37510.1 - 0.043 12.5 0.2 0.062 12.0 0.2 1.1 1 0 0 1 1 1 0 Hamartin protein Plasmodium_Vir PF05795.11 CEG37510.1 - 0.12 11.8 4.5 0.21 11.0 4.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SDA1 PF05285.12 CEG37510.1 - 0.24 10.8 13.4 0.35 10.2 13.4 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CEG37510.1 - 2.6 6.0 16.7 26 2.7 15.8 2.3 2 0 0 2 2 2 0 DNA polymerase phi Apt1 PF10351.9 CEG37510.1 - 5.5 5.7 12.4 8.9 5.0 12.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CEG37510.1 - 7.5 5.0 10.8 11 4.4 10.8 1.1 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 CEG37511.1 - 3.1e-60 199.9 0.0 1.9e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG37511.1 - 2.8e-05 24.1 0.0 0.81 9.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif YflT PF11181.8 CEG37511.1 - 3.4e-05 24.3 0.1 0.13 12.7 0.0 3.2 3 0 0 3 3 3 2 Heat induced stress protein YflT Limkain-b1 PF11608.8 CEG37511.1 - 7.4e-05 22.8 0.1 3.9 7.6 0.0 3.7 3 1 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 CEG37511.1 - 0.00011 22.1 0.0 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 CEG37511.1 - 0.00026 20.8 0.0 0.47 10.4 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CEG37511.1 - 0.00035 20.2 0.0 1.2 8.7 0.0 3.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CEG37511.1 - 0.0079 16.2 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 0 DbpA RNA binding domain ATP-grasp_2 PF08442.10 CEG37511.1 - 0.02 14.5 0.3 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 ATP-grasp domain RRM_Rrp7 PF17799.1 CEG37511.1 - 0.076 12.8 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FleQ PF06490.11 CEG37511.1 - 0.19 12.1 0.0 5.9 7.3 0.0 2.6 2 1 1 3 3 3 0 Flagellar regulatory protein FleQ DUF4944 PF16302.5 CEG37511.1 - 0.26 11.4 3.6 13 5.9 0.5 4.0 2 1 1 4 4 4 0 Domain of unknown function (DUF4944) WD40 PF00400.32 CEG37512.1 - 2.1e-19 69.5 15.7 0.0023 18.7 0.1 9.0 8 1 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG37512.1 - 5e-10 39.6 0.1 0.8 10.0 0.0 6.3 6 2 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 CEG37512.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 HELP motif LysE PF01810.18 CEG37513.1 - 3.6e-16 59.2 6.6 3.6e-16 59.2 6.6 1.9 2 0 0 2 2 2 1 LysE type translocator Dynein_attach_N PF15867.5 CEG37514.1 - 2.6e-18 65.7 0.8 2.6e-18 65.7 0.8 1.7 2 0 0 2 2 2 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 CEG37514.1 - 1.6e-13 51.0 0.2 4.5e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 KIAA1430 PF13879.6 CEG37515.1 - 1.7e-27 96.1 13.4 3.2e-27 95.3 13.4 1.4 1 0 0 1 1 1 1 KIAA1430 homologue TMCO5 PF14992.6 CEG37515.1 - 0.022 14.4 0.4 0.022 14.4 0.4 2.1 1 1 1 2 2 2 0 TMCO5 family FH2 PF02181.23 CEG37516.1 - 1.8e-29 103.0 7.1 2.4e-25 89.4 0.6 2.5 3 0 0 3 3 3 2 Formin Homology 2 Domain Ank_2 PF12796.7 CEG37516.1 - 2.7e-29 101.6 5.6 9.2e-12 45.4 0.9 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG37516.1 - 2.4e-24 85.4 4.8 2.1e-12 47.3 0.8 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CEG37516.1 - 9e-20 70.2 11.3 2.7e-05 24.4 0.1 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CEG37516.1 - 1.5e-17 61.8 10.2 0.0004 20.6 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CEG37516.1 - 4.6e-14 52.3 10.8 0.00041 20.6 1.2 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) WW PF00397.26 CEG37516.1 - 1.7e-06 28.0 4.3 3.5e-06 27.0 4.3 1.5 1 0 0 1 1 1 1 WW domain C2 PF00168.30 CEG37516.1 - 2.2e-05 24.7 0.0 5.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 CEG37516.1 - 0.00027 21.5 0.0 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CEG37516.1 - 0.0044 17.5 0.1 0.015 15.8 0.1 2.0 1 0 0 1 1 1 1 PH domain Mito_carr PF00153.27 CEG37517.1 - 3e-68 225.8 5.4 3e-25 88.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Radial_spoke_3 PF06098.11 CEG37518.1 - 7.6e-97 324.0 4.4 8.6e-97 323.8 4.4 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 FadA PF09403.10 CEG37518.1 - 2.7 8.5 13.9 0.17 12.4 5.3 2.5 2 1 0 2 2 2 0 Adhesion protein FadA GTP_EFTU_D3 PF03143.17 CEG37519.1 - 7.6e-23 80.9 0.6 6.3e-22 78.0 0.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain TnsD PF15978.5 CEG37519.1 - 0.054 12.5 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Glutaredoxin PF00462.24 CEG37520.1 - 4.2e-58 193.4 0.0 1.4e-18 66.8 0.0 3.9 4 0 0 4 4 4 3 Glutaredoxin SH3BGR PF04908.15 CEG37520.1 - 3.2e-09 36.8 0.0 0.032 14.4 0.0 3.6 3 0 0 3 3 3 3 SH3-binding, glutamic acid-rich protein Thioredoxin PF00085.20 CEG37520.1 - 5.4e-07 29.6 0.0 1.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.6 CEG37520.1 - 0.0054 17.1 0.0 0.95 9.9 0.0 3.4 4 0 0 4 4 4 1 Glutathione S-transferase, N-terminal domain MgtE_N PF03448.17 CEG37520.1 - 0.0054 17.3 0.2 0.019 15.5 0.2 2.0 1 0 0 1 1 1 1 MgtE intracellular N domain PPR PF01535.20 CEG37520.1 - 0.031 14.5 2.5 4.8 7.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat TrbC_Ftype PF09673.10 CEG37520.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TFIIA_gamma_N PF02268.16 CEG37520.1 - 0.076 13.0 1.8 13 5.9 0.1 2.9 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF2535 PF10751.9 CEG37520.1 - 0.13 12.8 0.2 1.1e+02 3.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2535) FYVE PF01363.21 CEG37521.1 - 7.4e-17 61.3 7.7 7.4e-17 61.3 7.7 4.1 3 2 1 4 4 3 1 FYVE zinc finger Arm PF00514.23 CEG37521.1 - 3.2e-09 36.5 1.1 4 7.6 0.0 7.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat zf-LSD1 PF06943.12 CEG37521.1 - 6.3e-06 25.9 22.0 0.00013 21.7 3.6 5.0 5 0 0 5 5 5 2 LSD1 zinc finger Zn-ribbon_8 PF09723.10 CEG37521.1 - 0.035 14.2 0.2 0.035 14.2 0.2 5.5 4 1 1 5 5 4 0 Zinc ribbon domain Dynein_AAA_lid PF17852.1 CEG37521.1 - 0.038 14.1 0.0 0.37 10.9 0.0 2.8 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain HEAT_2 PF13646.6 CEG37521.1 - 0.11 12.9 5.1 11 6.5 0.0 4.9 5 0 0 5 5 4 0 HEAT repeats QH-AmDH_gamma PF08992.11 CEG37521.1 - 0.12 12.4 0.4 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, gamma subunit HEAT PF02985.22 CEG37521.1 - 0.15 12.4 0.2 5.4 7.6 0.0 4.0 4 0 0 4 4 2 0 HEAT repeat XAF1_C PF18608.1 CEG37521.1 - 0.45 10.1 4.7 2.9 7.5 0.4 3.0 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain Tim54 PF11711.8 CEG37521.1 - 2.4 6.9 8.1 5.1 5.8 8.1 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mu-like_Com PF10122.9 CEG37521.1 - 8.3 5.9 12.7 0.95 9.0 2.3 3.9 2 1 1 3 3 3 0 Mu-like prophage protein Com Ribosomal_L27A PF00828.19 CEG37522.1 - 1.1e-23 84.4 0.1 2e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SIS PF01380.22 CEG37522.1 - 5.8e-16 58.5 0.0 2e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 CEG37522.1 - 4.4e-05 23.5 0.1 0.36 10.8 0.0 3.0 2 1 1 3 3 3 2 SIS domain Pkinase PF00069.25 CEG37523.1 - 1.3e-18 67.3 0.0 2.3e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37523.1 - 2.4e-12 46.7 0.0 5.2e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_10 PF05971.12 CEG37524.1 - 5.7e-67 226.2 0.9 8.8e-66 222.3 0.9 2.1 1 1 0 1 1 1 1 RNA methyltransferase AAA PF00004.29 CEG37524.1 - 2.3e-61 206.0 0.0 9.2e-31 107.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG37524.1 - 4.8e-15 55.1 1.3 1.6e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEG37524.1 - 6.5e-11 42.9 1.4 4.6e-06 27.1 0.0 4.3 3 1 0 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 CEG37524.1 - 4e-09 36.1 0.1 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 CEG37524.1 - 8.7e-09 35.4 0.0 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein MTS PF05175.14 CEG37524.1 - 3e-08 33.4 0.1 9.1e-08 31.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase small domain AAA_18 PF13238.6 CEG37524.1 - 4.1e-08 33.8 0.0 0.0013 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEG37524.1 - 6.9e-08 32.8 0.0 0.0081 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CEG37524.1 - 2.6e-07 30.5 0.2 0.036 13.8 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG37524.1 - 1.3e-06 28.7 0.3 0.004 17.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEG37524.1 - 2e-06 27.8 0.5 0.049 13.5 0.0 3.7 2 1 0 3 3 3 2 NACHT domain AAA_2 PF07724.14 CEG37524.1 - 5.4e-06 26.6 0.0 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 CEG37524.1 - 8.1e-06 25.8 0.6 0.0077 16.2 0.0 3.6 4 0 0 4 4 3 1 NTPase Zeta_toxin PF06414.12 CEG37524.1 - 3e-05 23.4 0.0 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 CEG37524.1 - 3.1e-05 24.4 0.0 0.028 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEG37524.1 - 3.7e-05 23.5 0.0 0.003 17.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 CEG37524.1 - 0.00011 22.2 0.0 0.2 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEG37524.1 - 0.00041 20.7 0.0 0.66 10.4 0.0 2.9 2 0 0 2 2 2 1 RNA helicase T2SSE PF00437.20 CEG37524.1 - 0.0005 19.2 0.0 0.0012 18.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein MCM PF00493.23 CEG37524.1 - 0.00074 18.7 0.0 0.016 14.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_24 PF13479.6 CEG37524.1 - 0.00081 19.2 0.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEG37524.1 - 0.0011 19.3 0.7 0.22 11.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CEG37524.1 - 0.0015 18.6 0.0 0.46 10.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 CEG37524.1 - 0.0017 18.4 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CEG37524.1 - 0.0023 17.3 0.3 0.55 9.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CEG37524.1 - 0.0024 17.0 0.1 2.2 7.3 0.0 2.6 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CEG37524.1 - 0.0036 17.2 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PrmA PF06325.13 CEG37524.1 - 0.0041 16.6 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AAA_28 PF13521.6 CEG37524.1 - 0.0046 17.2 0.1 0.19 12.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG37524.1 - 0.005 17.4 0.4 1.7 9.2 0.0 3.1 2 1 0 2 2 2 1 ABC transporter KTI12 PF08433.10 CEG37524.1 - 0.0065 15.9 0.0 0.95 8.9 0.0 2.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Bac_DnaA PF00308.18 CEG37524.1 - 0.0086 15.9 0.0 2.9 7.7 0.0 3.3 3 1 0 3 3 3 1 Bacterial dnaA protein cobW PF02492.19 CEG37524.1 - 0.011 15.3 0.2 0.46 10.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CEG37524.1 - 0.014 15.3 0.0 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 CEG37524.1 - 0.017 14.5 0.0 11 5.4 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG37524.1 - 0.019 14.7 0.1 0.52 10.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CEG37524.1 - 0.024 14.4 0.4 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CEG37524.1 - 0.032 14.4 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 CEG37524.1 - 0.039 13.8 0.1 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 CEG37524.1 - 0.049 12.8 0.2 11 5.2 0.0 2.9 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 CEG37524.1 - 0.062 12.8 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 CEG37524.1 - 0.097 11.8 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CEG37524.1 - 0.11 12.2 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Methyltransf_18 PF12847.7 CEG37524.1 - 0.13 12.2 0.0 0.48 10.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.23 CEG37524.1 - 0.15 12.1 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2075 PF09848.9 CEG37524.1 - 0.16 11.2 0.6 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CEG37524.1 - 2.7 8.5 9.0 11 6.5 0.1 3.2 3 1 0 3 3 2 0 AAA domain RXLR_WY PF18634.1 CEG37527.1 - 5.5e-05 23.0 3.4 0.065 13.2 3.2 3.5 3 0 0 3 3 3 2 RXLR phytopathogen effector protein WY-domain RXLR PF16810.5 CEG37527.1 - 0.039 14.4 0.2 0.16 12.4 0.0 2.1 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity bZIP_1 PF00170.21 CEG37529.1 - 0.00028 20.9 4.8 0.041 14.0 1.8 2.4 2 0 0 2 2 2 2 bZIP transcription factor AlaDh_PNT_N PF05222.15 CEG37529.1 - 0.074 13.4 0.0 29 5.0 0.0 3.6 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, N-terminal domain CENP-F_leu_zip PF10473.9 CEG37529.1 - 0.085 12.9 3.0 0.17 11.9 3.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MDMPI_N PF11716.8 CEG37529.1 - 0.14 12.9 0.2 10 6.8 0.1 2.3 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Enkurin PF13864.6 CEG37529.1 - 0.54 10.7 3.7 0.72 10.3 0.7 2.2 1 1 1 2 2 2 0 Calmodulin-binding bZIP_2 PF07716.15 CEG37529.1 - 1.8 8.7 8.7 3 8.0 2.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUSP PF06337.12 CEG37530.1 - 1.8e-09 38.1 0.1 3.2e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 DUSP domain Pkinase PF00069.25 CEG37532.1 - 1.2e-44 152.7 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37532.1 - 1.4e-24 86.8 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG37532.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG37532.1 - 4.1e-06 26.5 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CEG37532.1 - 5.4e-05 23.2 1.0 0.006 16.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG37532.1 - 0.00033 20.1 0.0 0.00051 19.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 CEG37532.1 - 0.004 16.7 0.1 0.0073 15.9 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CEG37532.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_1 PF00076.22 CEG37533.1 - 1.3e-35 121.1 0.0 7.7e-17 60.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CEG37533.1 - 1.8e-30 104.2 35.0 5e-06 26.3 0.8 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG37533.1 - 2.7e-26 90.8 60.5 7.9e-07 28.9 4.2 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_4 PF18044.1 CEG37533.1 - 3.8e-20 71.2 38.8 1.2e-05 25.0 1.3 5.4 5 0 0 5 5 5 5 CCCH-type zinc finger Torus PF16131.5 CEG37533.1 - 2.1e-15 57.3 32.4 9.8e-05 23.0 1.3 5.6 2 2 3 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 CEG37533.1 - 4.6e-09 36.5 25.8 0.11 12.7 1.3 5.3 2 2 3 5 5 5 5 Zinc-finger containing family RRM_7 PF16367.5 CEG37533.1 - 8.7e-09 35.4 0.1 0.00031 20.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif zf-CCCH_2 PF14608.6 CEG37533.1 - 0.0006 20.2 41.8 0.017 15.6 1.3 5.6 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger Nup35_RRM_2 PF14605.6 CEG37533.1 - 0.0047 16.9 0.3 0.095 12.7 0.3 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Sld5 PF05916.11 CEG37535.1 - 1.4e-19 70.5 1.0 2.4e-19 69.8 1.0 1.4 1 0 0 1 1 1 1 GINS complex protein PX PF00787.24 CEG37536.1 - 6.8e-10 38.9 0.2 1.9e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 PX domain DUF872 PF05915.12 CEG37536.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Aida_C2 PF14186.6 CEG37537.1 - 1.2e-52 177.5 0.1 1.6e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 CEG37537.1 - 1.6e-18 67.0 0.0 4.5e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Aida N-terminus Sec6 PF06046.13 CEG37538.1 - 1.4e-38 132.6 15.2 1.7e-38 132.4 14.3 1.5 1 1 1 2 2 2 1 Exocyst complex component Sec6 zf-RING_2 PF13639.6 CEG37542.1 - 4.1e-13 49.4 6.4 8.9e-13 48.4 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG37542.1 - 5.6e-09 36.2 7.1 2.4e-08 34.1 7.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG37542.1 - 1.5e-08 34.3 6.2 3e-08 33.4 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG37542.1 - 2.1e-08 33.8 3.7 5.1e-08 32.5 3.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 CEG37542.1 - 5.9e-08 32.4 4.0 1.3e-07 31.3 4.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEG37542.1 - 9.1e-08 31.8 3.3 1.7e-07 30.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG37542.1 - 1.2e-07 31.5 5.9 2.4e-07 30.5 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG37542.1 - 1.3e-06 28.2 4.7 2.6e-06 27.3 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG37542.1 - 6.5e-05 22.9 4.7 6.5e-05 22.9 4.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CEG37542.1 - 0.00072 19.6 2.2 0.0018 18.3 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CEG37542.1 - 0.0016 18.0 4.9 0.0033 17.0 4.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CEG37542.1 - 0.03 14.5 4.4 0.078 13.1 4.0 2.0 1 1 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.14 CEG37542.1 - 0.054 13.3 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3H2C3 PF17122.5 CEG37542.1 - 0.087 12.9 1.8 0.22 11.6 1.8 1.7 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CEG37542.1 - 0.33 10.9 4.6 1.9 8.5 1.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 CEG37542.1 - 0.48 10.6 4.7 3.6 7.8 4.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Sporozoite_P67 PF05642.11 CEG37542.1 - 0.57 8.2 3.5 0.79 7.7 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING-like PF08746.11 CEG37542.1 - 0.59 10.5 4.8 1.6 9.1 4.7 1.8 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 CEG37542.1 - 0.84 9.8 5.8 1.9 8.7 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING XPG_I PF00867.18 CEG37543.1 - 1.6e-23 82.9 0.2 3.9e-23 81.6 0.2 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEG37543.1 - 2.1e-23 82.7 0.0 5.6e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEG37543.1 - 8.8e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 CEG37543.1 - 0.024 14.7 0.1 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat 5_3_exonuc PF01367.20 CEG37543.1 - 0.033 14.8 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold SUI1 PF01253.22 CEG37546.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CEG37546.1 - 3.9e-06 27.5 0.0 8.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CEG37546.1 - 2.6e-05 24.1 0.4 6.7e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 PUA domain Kin17_mid PF10357.9 CEG37546.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 CEG37546.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain PGAP1 PF07819.13 CEG37547.1 - 1.6e-51 175.3 0.1 2.6e-51 174.6 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CEG37547.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG37547.1 - 0.0028 18.3 0.0 0.0058 17.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CEG37547.1 - 0.045 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MnhB PF04039.13 CEG37547.1 - 7 7.0 15.3 6.7 7.0 5.1 3.1 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter MFS_1 PF07690.16 CEG37548.1 - 1.1e-20 73.8 32.2 1.7e-20 73.3 32.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 CEG37548.1 - 5e-15 56.3 16.5 8e-07 29.3 9.1 3.1 1 1 2 3 3 3 3 SPX domain Sugar_tr PF00083.24 CEG37548.1 - 1.1e-06 27.9 7.3 1.1e-06 27.9 7.3 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter AAA PF00004.29 CEG37549.1 - 4e-41 140.5 0.0 2e-39 135.0 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 CEG37549.1 - 4.8e-20 71.4 0.2 1.3e-19 70.0 0.2 1.8 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 CEG37549.1 - 5.1e-12 45.4 0.1 5.9e-11 42.0 0.1 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 CEG37549.1 - 7.8e-06 26.1 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEG37549.1 - 4.8e-05 23.8 0.2 0.0016 18.9 0.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 CEG37549.1 - 7.9e-05 22.5 7.8 0.00019 21.3 7.8 1.7 1 0 0 1 1 1 1 PHD-finger AAA_28 PF13521.6 CEG37549.1 - 0.00026 21.3 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CEG37549.1 - 0.0004 20.7 0.1 0.0041 17.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain zf-HC5HC2H PF13771.6 CEG37549.1 - 0.00058 20.1 3.3 0.0016 18.7 3.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain AAA_33 PF13671.6 CEG37549.1 - 0.00084 19.5 0.1 0.032 14.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEG37549.1 - 0.0038 17.2 0.1 0.027 14.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 CEG37549.1 - 0.0058 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 CEG37549.1 - 0.0078 15.6 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI zf-PHD-like PF15446.6 CEG37549.1 - 0.024 14.3 3.4 0.096 12.3 3.4 2.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain IstB_IS21 PF01695.17 CEG37549.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CEG37549.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CEG37549.1 - 0.047 14.2 0.0 0.047 14.2 0.0 2.9 4 0 0 4 4 1 0 AAA domain RuvB_N PF05496.12 CEG37549.1 - 0.049 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zf_RING PF16744.5 CEG37549.1 - 0.12 12.5 2.5 0.43 10.7 2.5 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CEG37549.1 - 0.13 12.3 6.0 0.3 11.0 6.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 LicD PF04991.13 CEG37549.1 - 0.55 10.3 3.7 1 9.5 3.0 1.9 1 1 0 1 1 1 0 LicD family Orf78 PF06024.12 CEG37550.1 - 0.074 13.3 0.3 9.6 6.6 0.1 3.5 3 0 0 3 3 3 0 Orf78 (ac78) DUF2418 PF10332.9 CEG37550.1 - 0.093 13.3 0.4 0.64 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Ilm1 PF10311.9 CEG37550.1 - 0.13 11.9 1.9 0.88 9.2 0.7 2.5 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Cas1_AcylT PF07779.12 CEG37550.1 - 4.4 6.1 10.0 4.2 6.2 7.1 2.3 2 1 0 2 2 2 0 10 TM Acyl Transferase domain found in Cas1p EcoEI_R_C PF08463.10 CEG37551.1 - 0.054 13.6 1.2 7 6.7 0.1 2.4 2 0 0 2 2 2 0 EcoEI R protein C-terminal DUF4519 PF15012.6 CEG37551.1 - 0.36 11.0 2.8 2.1 8.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) C2 PF00168.30 CEG37552.1 - 1.5e-19 70.2 0.0 2.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain mTERF PF02536.14 CEG37553.1 - 1.2e-29 103.2 0.1 1.3e-20 73.6 0.0 2.4 1 1 1 2 2 2 2 mTERF DUF3243 PF11588.8 CEG37553.1 - 0.0015 18.8 0.0 5.5 7.4 0.0 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3243) TetR_C_1 PF02909.17 CEG37553.1 - 0.017 14.9 0.0 9.3 6.1 0.0 3.2 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain UBA_6 PF18039.1 CEG37553.1 - 0.033 14.1 0.0 4.4 7.3 0.0 3.5 4 0 0 4 4 4 0 UBA-like domain 3HCDH_N PF02737.18 CEG37555.1 - 2.6e-53 180.6 0.6 5.2e-53 179.6 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 CEG37555.1 - 9.5e-45 152.9 3.1 1.9e-44 151.9 0.8 2.5 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 CEG37555.1 - 7.5e-35 119.4 0.0 2.9e-25 88.7 0.0 3.4 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 CEG37555.1 - 4.3e-30 105.3 0.3 9e-30 104.3 0.3 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_8 PF13450.6 CEG37555.1 - 0.072 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ras PF00071.22 CEG37556.1 - 3e-50 170.0 0.0 2.5e-49 167.0 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CEG37556.1 - 4.5e-21 75.3 0.0 1.8e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Abhydrolase_1 PF00561.20 CEG37556.1 - 2.1e-16 60.4 0.2 9.9e-12 45.0 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG37556.1 - 5.3e-14 52.1 0.0 1.1e-11 44.5 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Arf PF00025.21 CEG37556.1 - 7.9e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AXE1 PF05448.12 CEG37556.1 - 4.6e-08 32.1 0.1 0.01 14.6 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 CEG37556.1 - 1.2e-06 29.3 0.0 2.9e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CEG37556.1 - 1.8e-05 24.4 0.0 0.00015 21.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CEG37556.1 - 2.6e-05 24.2 0.0 0.0034 17.2 0.0 3.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CEG37556.1 - 3.1e-05 23.6 0.0 0.00019 21.0 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CEG37556.1 - 0.0034 17.0 0.0 1.6 8.2 0.0 2.4 2 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 CEG37556.1 - 0.017 14.9 0.0 0.73 9.6 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1100 PF06500.11 CEG37556.1 - 0.022 13.6 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF1057 PF06342.12 CEG37556.1 - 0.022 13.8 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 CEG37556.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 CEG37556.1 - 0.095 12.5 0.1 0.3 10.9 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold BLOC1_2 PF10046.9 CEG37557.1 - 3.2e-18 65.8 6.2 3.9e-18 65.5 6.2 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CEG37557.1 - 0.0023 18.0 3.3 0.13 12.3 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Med9 PF07544.13 CEG37557.1 - 0.0097 16.0 0.8 0.2 11.8 0.1 2.3 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.18 CEG37557.1 - 0.011 15.0 1.2 0.012 14.9 1.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF722 PF05263.11 CEG37557.1 - 0.022 15.0 3.5 0.032 14.4 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF722) DUF3450 PF11932.8 CEG37557.1 - 0.024 14.0 2.6 0.029 13.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 CEG37557.1 - 0.024 14.7 3.0 0.033 14.2 2.1 1.6 1 1 1 2 2 2 0 Laminin Domain II CLZ PF16526.5 CEG37557.1 - 0.026 14.9 4.6 0.052 13.9 1.1 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 CEG37557.1 - 0.028 14.3 2.9 0.31 10.9 0.3 2.0 1 1 1 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 CEG37557.1 - 0.031 14.5 4.1 0.049 13.8 4.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Lge1 PF11488.8 CEG37557.1 - 0.051 13.8 4.6 0.045 13.9 2.8 1.9 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF3552 PF12072.8 CEG37557.1 - 0.052 13.0 0.8 0.062 12.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DASH_Dam1 PF08653.10 CEG37557.1 - 0.071 12.9 0.8 0.071 12.9 0.8 2.6 2 1 0 3 3 3 0 DASH complex subunit Dam1 Fes1 PF08609.10 CEG37557.1 - 0.071 14.0 4.2 0.15 13.0 4.2 1.5 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF745 PF05335.13 CEG37557.1 - 0.1 12.3 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Ima1_N PF09779.9 CEG37557.1 - 0.12 13.2 0.4 0.24 12.3 0.4 1.5 1 1 0 1 1 1 0 Ima1 N-terminal domain TMF_DNA_bd PF12329.8 CEG37557.1 - 0.13 12.2 0.6 0.13 12.2 0.6 1.8 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding CCDC53 PF10152.9 CEG37557.1 - 0.15 12.4 2.7 2 8.8 0.4 2.1 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Nsp1_C PF05064.13 CEG37557.1 - 0.2 11.5 4.0 0.31 10.9 3.7 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region V-SNARE PF05008.15 CEG37557.1 - 0.35 11.3 4.3 0.24 11.8 1.0 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus BLI1 PF17324.2 CEG37557.1 - 0.44 11.2 5.9 0.71 10.6 5.9 1.5 1 1 0 1 1 1 0 BLOC-1 interactor 1 ABC_tran_CTD PF16326.5 CEG37557.1 - 0.9 9.8 5.3 0.55 10.5 3.0 1.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 CEG37557.1 - 9 6.5 6.3 11 6.2 1.0 2.9 2 1 2 4 4 4 0 bZIP transcription factor PX PF00787.24 CEG37558.1 - 1.3e-08 34.8 0.0 3.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PX domain UBA_3 PF09288.10 CEG37559.1 - 0.0018 18.0 0.0 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain DDE_Tnp_1_assoc PF13808.6 CEG37564.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-associated DUF4768 PF15989.5 CEG37567.1 - 0.082 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) WD40 PF00400.32 CEG37568.1 - 4.7e-64 210.8 24.8 4.6e-08 33.6 0.0 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 CEG37568.1 - 1.5e-38 131.9 0.1 2.5e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CEG37568.1 - 1.3e-17 63.9 5.4 4.5e-05 23.7 0.0 8.2 5 2 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG37568.1 - 4.9e-10 38.9 10.2 0.16 10.9 0.2 7.2 2 2 5 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CEG37568.1 - 5.3e-09 35.1 0.2 2e-06 26.6 0.1 3.8 4 0 0 4 4 4 1 Cytochrome D1 heme domain Nup160 PF11715.8 CEG37568.1 - 6.1e-07 28.5 12.7 0.18 10.4 0.0 5.9 4 2 1 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CEG37568.1 - 0.00079 18.8 0.1 0.98 8.7 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 CEG37568.1 - 0.0012 17.7 0.7 1.4 7.6 0.0 4.1 3 2 1 4 4 4 1 Nup133 N terminal like Pox_TAP PF03355.14 CEG37568.1 - 0.013 15.1 1.0 13 5.2 0.0 3.4 2 1 1 3 3 3 0 Viral Trans-Activator Protein VID27 PF08553.10 CEG37568.1 - 0.023 13.8 0.0 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain nos_propeller PF18764.1 CEG37568.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat PALB2_WD40 PF16756.5 CEG37568.1 - 0.21 10.5 5.2 0.4 9.5 0.4 3.3 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DUF3716 PF12511.8 CEG37569.1 - 0.044 13.8 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Myosin_head PF00063.21 CEG37571.1 - 1.7e-233 776.8 0.2 2.3e-233 776.3 0.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CEG37571.1 - 4.9e-17 62.2 0.0 3.2e-12 46.5 0.0 2.7 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding zf-Tim10_DDP PF02953.15 CEG37571.1 - 4.3e-13 48.7 2.7 1.3e-12 47.1 2.7 1.9 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FYVE PF01363.21 CEG37571.1 - 6.7e-11 42.2 0.9 5e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 FYVE zinc finger Hpr_kinase_C PF07475.12 CEG37571.1 - 0.0014 18.1 0.0 0.25 10.8 0.0 2.7 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 CEG37571.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEG37571.1 - 0.27 11.6 1.5 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Nop53 PF07767.11 CEG37571.1 - 2.2 7.6 21.5 4 6.7 21.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1682 PF07946.14 CEG37571.1 - 4.3 6.5 18.2 9.1 5.4 18.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_L4 PF00573.22 CEG37572.1 - 3.1e-68 229.3 0.1 3.8e-68 229.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Pkinase PF00069.25 CEG37573.1 - 3.9e-12 46.1 0.1 6.9e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 CEG37573.1 - 0.0011 17.8 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG37573.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CEG37575.1 - 2.6e-12 46.7 3.4 6e-10 38.9 1.3 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 CEG37575.1 - 1.6e-06 27.2 0.0 2.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEG37575.1 - 5.9e-06 25.8 3.6 0.003 16.9 2.4 3.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEG37575.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG37575.1 - 0.093 12.1 0.1 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Not3 PF04065.15 CEG37576.1 - 1.7e-84 282.9 19.0 1.7e-84 282.9 19.0 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component PALP PF00291.25 CEG37576.1 - 6.2e-57 193.3 3.2 4.9e-29 101.7 0.3 2.3 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme NOT2_3_5 PF04153.18 CEG37576.1 - 7.9e-43 145.7 7.1 2.3e-42 144.2 7.1 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DegT_DnrJ_EryC1 PF01041.17 CEG37576.1 - 0.027 13.8 2.4 0.62 9.3 0.1 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1664 PF07889.12 CEG37576.1 - 3.3 7.8 8.1 2.3 8.3 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 CEG37576.1 - 5 7.5 12.4 13 6.2 1.7 2.7 2 0 0 2 2 2 0 Syntaxin-like protein Med29 PF11568.8 CEG37577.1 - 0.0035 17.5 0.3 0.0043 17.3 0.3 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF4570 PF15134.6 CEG37577.1 - 0.0068 16.4 1.0 0.17 11.9 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4570) DUF2935 PF11155.8 CEG37577.1 - 0.093 13.1 0.3 0.2 12.0 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF150 PF02576.17 CEG37578.1 - 0.096 13.1 0.1 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 RimP N-terminal domain HAT_KAT11 PF08214.11 CEG37579.1 - 4.8e-18 65.5 0.1 1.1e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 CEG37579.1 - 1.2e-14 54.1 0.0 2.8e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DENN PF02141.21 CEG37579.1 - 1.5e-14 54.4 0.9 3.7e-14 53.1 0.9 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 CEG37579.1 - 3.1e-10 40.3 1.9 0.00036 20.8 0.1 3.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain Polysacc_deac_1 PF01522.21 CEG37580.1 - 1.6e-16 60.4 0.0 4e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase Cofilin_ADF PF00241.20 CEG37581.1 - 4.8e-35 120.0 0.1 5.4e-35 119.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HEAT_EZ PF13513.6 CEG37582.1 - 0.0001 22.7 1.9 0.33 11.5 0.0 4.0 4 0 0 4 4 4 2 HEAT-like repeat Rcd1 PF04078.13 CEG37582.1 - 0.00032 20.1 2.7 0.0016 17.8 2.2 2.5 1 1 1 2 2 2 1 Cell differentiation family, Rcd1-like Arm PF00514.23 CEG37582.1 - 0.00078 19.4 2.6 1.7 8.8 0.0 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CEG37582.1 - 0.0013 18.8 0.5 0.0013 18.8 0.5 2.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 CEG37582.1 - 0.0043 17.3 2.8 0.73 10.2 0.2 3.4 1 1 1 3 3 3 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 CEG37582.1 - 0.005 17.2 3.8 0.014 15.7 0.0 3.3 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CEG37582.1 - 0.007 16.5 9.3 0.08 13.2 0.0 4.8 6 0 0 6 6 6 1 HEAT repeat V-ATPase_H_N PF03224.14 CEG37582.1 - 0.019 14.3 3.3 0.049 12.9 0.8 2.0 1 1 0 2 2 2 0 V-ATPase subunit H C2 PF00168.30 CEG37583.1 - 2e-22 79.4 0.1 2.7e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF2076 PF09849.9 CEG37583.1 - 0.00042 20.4 15.6 0.00042 20.4 15.6 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Drf_FH1 PF06346.12 CEG37583.1 - 8 6.2 41.7 14 5.3 41.7 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 PDZ PF00595.24 CEG37585.1 - 4.2e-14 52.7 0.0 0.013 15.8 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CEG37585.1 - 1.5e-10 40.7 0.2 0.13 12.2 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CEG37585.1 - 0.0018 18.6 0.1 7.7 6.9 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Glyco_hydro_79n PF03662.14 CEG37585.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain DUF1039 PF06287.11 CEG37586.1 - 0.05 14.0 0.1 0.43 11.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1039) DUF3267 PF11667.8 CEG37586.1 - 0.054 13.8 0.5 0.054 13.8 0.5 1.9 2 0 0 2 2 2 0 Putative zincin peptidase Pkinase PF00069.25 CEG37587.1 - 2.7e-57 194.1 0.0 3.7e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37587.1 - 4.5e-42 144.1 0.0 6.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG37587.1 - 1.5e-08 34.3 0.3 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CEG37587.1 - 2.6e-05 23.2 3.8 5.3e-05 22.2 0.0 2.6 2 1 1 3 3 3 1 Fungal protein kinase Kdo PF06293.14 CEG37587.1 - 0.00031 20.2 0.1 0.00066 19.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEG37587.1 - 0.028 13.9 0.2 0.077 12.5 0.0 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L33 PF00471.20 CEG37588.1 - 0.00027 21.3 0.1 0.00039 20.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 Kelch_5 PF13854.6 CEG37590.1 - 1.2e-26 92.2 4.9 2.3e-05 24.3 0.1 6.1 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CEG37590.1 - 4.2e-22 77.6 3.4 3.1e-05 24.1 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CEG37590.1 - 2.5e-21 75.4 4.8 1.6e-05 24.8 0.0 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG37590.1 - 3.7e-21 74.4 0.0 1.3e-06 27.9 0.0 5.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CEG37590.1 - 5.8e-21 74.3 16.1 0.00015 21.9 0.1 9.1 7 1 0 7 7 7 5 Galactose oxidase, central domain fn3 PF00041.21 CEG37590.1 - 1.4e-16 60.6 0.2 5e-06 26.8 0.0 5.5 4 1 0 4 4 4 3 Fibronectin type III domain Kelch_2 PF07646.15 CEG37590.1 - 2e-12 46.6 1.2 0.00034 20.5 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Gly_rich PF12810.7 CEG37590.1 - 1.5e-09 38.2 70.1 6e-09 36.2 33.9 2.4 1 1 1 2 2 2 1 Glycine rich protein P_proprotein PF01483.20 CEG37590.1 - 0.00026 20.9 0.1 1.3 9.1 0.0 2.9 3 0 0 3 3 3 2 Proprotein convertase P-domain DDE_1 PF03184.19 CEG37592.1 - 0.00025 20.8 0.1 0.00039 20.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UbiA PF01040.18 CEG37596.1 - 1.2e-54 185.2 16.2 1.8e-54 184.7 16.2 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family RecX PF02631.16 CEG37598.1 - 0.011 16.1 0.1 0.57 10.6 0.1 3.0 2 1 1 3 3 3 0 RecX family CaiF_GrlA PF07180.11 CEG37598.1 - 0.027 14.5 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator UBA PF00627.31 CEG37598.1 - 0.033 14.1 0.6 54 3.8 0.0 3.8 4 0 0 4 4 4 0 UBA/TS-N domain RXLR PF16810.5 CEG37598.1 - 0.049 14.1 5.1 9 6.7 0.1 4.0 4 0 0 4 4 4 0 RXLR phytopathogen effector protein, Avirulence activity EcoR124_C PF12008.8 CEG37598.1 - 0.057 13.1 0.2 4.4 6.9 0.1 2.8 3 0 0 3 3 3 0 Type I restriction and modification enzyme - subunit R C terminal Death PF00531.22 CEG37598.1 - 0.092 12.9 0.2 5.6 7.2 0.0 3.2 4 0 0 4 4 4 0 Death domain HNOB PF07700.15 CEG37598.1 - 0.2 11.6 0.7 17 5.3 0.1 2.9 3 0 0 3 3 3 0 Haem-NO-binding mRNA_triPase PF02940.15 CEG37600.1 - 3.8e-19 69.3 0.0 9.4e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 CEG37600.1 - 9.2e-19 68.0 0.0 5e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CEG37600.1 - 0.00051 20.7 0.0 0.0014 19.2 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CEG37600.1 - 0.0059 16.3 0.0 0.58 9.8 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain bZIP_1 PF00170.21 CEG37601.1 - 1.4e-09 37.9 17.0 1.4e-09 37.9 17.0 3.6 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 CEG37601.1 - 1.2e-06 28.5 12.5 1.2e-06 28.5 12.5 3.2 3 1 0 3 3 3 1 Basic region leucine zipper YabA PF06156.13 CEG37601.1 - 0.096 13.3 14.3 0.96 10.1 1.2 2.8 2 1 1 3 3 3 0 Initiation control protein YabA DUF573 PF04504.14 CEG37601.1 - 0.1 13.3 2.8 0.51 11.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Med15_fungi PF05397.12 CEG37601.1 - 0.22 11.8 4.3 0.15 12.4 0.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 15 LTXXQ PF07813.12 CEG37601.1 - 0.29 11.9 10.0 2.4 8.9 0.2 3.4 2 2 1 3 3 3 0 LTXXQ motif family protein Bacillus_HBL PF05791.11 CEG37601.1 - 0.64 9.8 5.7 0.29 10.9 1.7 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Wtap PF17098.5 CEG37601.1 - 1.8 8.5 14.1 1.6 8.7 7.7 2.7 2 1 1 3 3 3 0 WTAP/Mum2p family NYD-SP28_assoc PF14775.6 CEG37601.1 - 4.5 7.5 6.9 3.2 7.9 0.8 3.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain TSC22 PF01166.18 CEG37601.1 - 6.5 7.2 10.6 1 9.7 0.7 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family DIRP PF06584.13 CEG37603.1 - 0.12 12.5 2.0 0.23 11.7 0.3 2.2 2 0 0 2 2 2 0 DIRP Pkinase PF00069.25 CEG37604.1 - 4.1e-38 131.3 0.0 2e-20 73.3 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37604.1 - 4.2e-13 49.2 0.1 1.2e-07 31.3 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG37604.1 - 0.0049 15.7 0.5 0.011 14.6 0.2 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG37604.1 - 0.0078 16.2 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family EF-hand_6 PF13405.6 CEG37605.1 - 8.7e-06 25.3 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEG37605.1 - 4.3e-05 22.8 0.0 0.38 10.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG37605.1 - 5.4e-05 23.6 4.6 0.00012 22.4 0.1 3.1 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.6 CEG37605.1 - 0.00035 20.8 0.1 0.28 11.5 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CEG37605.1 - 0.0029 17.4 0.1 0.43 10.5 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG37605.1 - 0.0051 16.3 0.0 0.99 9.0 0.0 2.7 2 0 0 2 2 2 2 EF hand Yip1 PF04893.17 CEG37607.1 - 4e-14 52.7 17.3 5e-14 52.4 17.3 1.2 1 0 0 1 1 1 1 Yip1 domain Copine PF07002.16 CEG37608.1 - 1.1e-46 159.0 0.0 1.5e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 CEG37608.1 - 4.3e-10 40.0 0.0 6.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 CEG37608.1 - 0.0098 16.2 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3055 PF11256.8 CEG37609.1 - 0.0093 16.2 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3055) NPP1 PF05630.11 CEG37612.1 - 5.7e-47 160.4 0.0 6.7e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) PA14 PF07691.12 CEG37613.1 - 0.032 14.0 0.4 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 PA14 domain Sporozoite_P67 PF05642.11 CEG37613.1 - 0.072 11.2 7.1 0.094 10.8 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 CEG37615.1 - 8.9 4.5 7.8 11 4.1 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PA14 PF07691.12 CEG37616.1 - 0.04 13.7 0.1 0.078 12.8 0.0 1.5 2 0 0 2 2 2 0 PA14 domain ATP-gua_Ptrans PF00217.19 CEG37619.1 - 1.7e-12 47.3 0.0 1.4e-09 37.8 0.0 2.0 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain TPR_1 PF00515.28 CEG37621.1 - 3.8e-14 51.8 0.0 2.2e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37621.1 - 7.8e-11 41.2 0.0 9.2e-05 22.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG37621.1 - 4.6e-08 33.6 0.0 3.1e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG37621.1 - 7.8e-07 29.2 0.0 0.0023 18.0 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37621.1 - 2.5e-06 27.9 0.0 5.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG37621.1 - 3.1e-06 26.8 0.0 0.069 12.8 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CEG37621.1 - 6e-06 26.1 0.0 0.27 11.6 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG37621.1 - 7.5e-05 22.8 0.0 0.088 13.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37621.1 - 0.0017 19.0 0.0 0.21 12.5 0.0 3.4 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG37621.1 - 0.0018 18.5 0.6 0.17 12.2 0.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEG37621.1 - 0.0082 16.5 0.0 0.26 11.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG37621.1 - 0.0092 16.2 0.3 0.61 10.4 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2401 PF10287.9 CEG37622.1 - 7.6e-53 179.5 0.1 1.2e-52 178.7 0.1 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CEG37622.1 - 1.2e-11 44.8 0.1 3.5e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) cwf21 PF08312.12 CEG37623.1 - 0.0029 17.7 0.8 0.21 11.7 0.0 3.7 2 2 0 2 2 2 1 cwf21 domain Filament PF00038.21 CEG37623.1 - 0.06 12.9 20.9 0.78 9.3 1.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF1269 PF06897.12 CEG37623.1 - 0.096 13.0 0.1 3.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) MerR_2 PF13591.6 CEG37623.1 - 0.79 9.6 5.9 0.9 9.5 4.1 2.1 1 1 0 1 1 1 0 MerR HTH family regulatory protein SlyX PF04102.12 CEG37623.1 - 0.81 10.3 15.8 0.3 11.8 0.6 3.6 1 1 1 3 3 3 0 SlyX Atg14 PF10186.9 CEG37623.1 - 3 6.8 8.8 4.7 6.2 8.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OSTbeta PF15048.6 CEG37624.1 - 0.079 13.1 0.9 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Myb_DNA-binding PF00249.31 CEG37625.1 - 5.4e-08 32.9 0.1 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain TCP PF03634.13 CEG37625.1 - 0.13 12.8 38.5 1.5 9.3 7.3 3.5 3 0 0 3 3 3 0 TCP family transcription factor TERB2 PF15101.6 CEG37625.1 - 1.4 8.9 47.5 3 7.8 4.6 3.5 3 0 0 3 3 3 0 Telomere-associated protein TERB2 AAA_11 PF13086.6 CEG37625.1 - 3.3 7.4 37.5 6 6.6 0.5 3.3 3 0 0 3 3 3 0 AAA domain Actin PF00022.19 CEG37627.1 - 1.9e-93 313.3 0.0 2e-91 306.7 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CEG37627.1 - 0.0011 19.3 0.0 0.034 14.6 0.0 2.4 2 1 0 2 2 2 1 Cell division protein FtsA Epimerase PF01370.21 CEG37628.1 - 4.8e-26 91.7 0.0 6.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEG37628.1 - 1.8e-19 70.3 0.3 9.5e-18 64.7 0.1 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CEG37628.1 - 6.4e-14 51.7 0.0 8.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEG37628.1 - 1.7e-11 43.9 0.2 3.5e-10 39.5 0.2 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CEG37628.1 - 1.8e-10 40.3 0.0 3.1e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEG37628.1 - 4.8e-08 32.5 0.1 2.7e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 CEG37628.1 - 0.085 12.8 0.5 0.98 9.3 0.5 2.2 1 1 0 1 1 1 0 KR domain Ephrin_rec_like PF07699.13 CEG37629.1 - 1.2e-10 40.9 20.1 8.8e-07 28.6 1.6 4.4 3 1 3 6 6 6 4 Putative ephrin-receptor like Furin-like PF00757.20 CEG37629.1 - 0.00066 19.6 5.2 0.019 14.9 0.3 2.3 1 1 0 2 2 2 2 Furin-like cysteine rich region NCD3G PF07562.14 CEG37629.1 - 0.018 15.0 15.1 0.68 9.9 2.6 3.8 2 1 2 4 4 4 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 CEG37629.1 - 0.19 12.2 10.8 3.3 8.2 0.3 4.4 2 1 3 5 5 5 0 TNFR/NGFR cysteine-rich region Pkinase_Tyr PF07714.17 CEG37631.1 - 7.3e-50 169.7 0.0 9.9e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG37631.1 - 5.1e-49 167.0 0.0 7.5e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 CEG37631.1 - 3.3e-05 23.6 9.8 0.0093 15.7 2.2 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEG37631.1 - 0.00014 22.2 15.5 0.0006 20.1 1.6 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) AMA-1 PF02430.15 CEG37631.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 APH PF01636.23 CEG37631.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG37631.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RXLR_WY PF18634.1 CEG37632.1 - 2.8e-08 33.5 3.3 0.046 13.6 0.0 4.1 4 0 0 4 4 4 3 RXLR phytopathogen effector protein WY-domain NolX PF05819.11 CEG37632.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 NolX protein DEFB136 PF17333.2 CEG37633.1 - 0.036 14.0 0.3 0.044 13.7 0.3 1.2 1 0 0 1 1 1 0 Beta defensin 136 Asp PF00026.23 CEG37637.1 - 2.5e-46 158.6 2.2 7e-31 107.8 1.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG37637.1 - 1.6e-11 44.8 1.3 1e-05 25.8 0.2 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEG37637.1 - 2.4e-05 24.9 0.1 5.8e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG37637.1 - 0.0024 18.4 0.0 0.0049 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CEG37637.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal HECT PF00632.25 CEG37638.1 - 3e-79 266.7 0.0 5.1e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 CEG37638.1 - 2.1e-05 23.7 3.4 3.9e-05 22.9 3.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CEG37638.1 - 0.037 13.4 0.4 0.095 12.1 0.4 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SUKH_5 PF14567.6 CEG37638.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall N_BRCA1_IG PF16158.5 CEG37639.1 - 4.3e-20 72.4 0.0 7.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 CEG37639.1 - 1.2e-12 47.5 5.3 7.8e-12 44.8 1.4 2.4 1 1 1 2 2 2 2 UBA-like domain TAP_C PF03943.13 CEG37639.1 - 0.013 15.1 1.3 0.025 14.2 0.4 1.9 2 0 0 2 2 2 0 TAP C-terminal domain CUE PF02845.16 CEG37639.1 - 0.071 12.8 0.1 0.071 12.8 0.1 1.9 2 0 0 2 2 2 0 CUE domain UBA PF00627.31 CEG37639.1 - 0.087 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Amidinotransf PF02274.17 CEG37640.1 - 1.8e-09 37.2 0.0 1.2e-06 27.9 0.0 3.5 3 1 0 3 3 3 2 Amidinotransferase PAD_porph PF04371.15 CEG37640.1 - 0.059 12.7 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase SF3A2 PF16835.5 CEG37642.1 - 9e-35 118.9 0.1 1.4e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CactinC_cactus PF09732.9 CEG37642.1 - 2.6e-05 24.1 0.1 4e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein zf-met PF12874.7 CEG37642.1 - 0.00022 21.5 0.5 0.00054 20.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type FA_desaturase PF00487.24 CEG37643.1 - 7.1e-33 114.5 20.2 7.1e-33 114.5 20.2 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEG37643.1 - 3.5e-17 62.3 0.5 6.9e-17 61.4 0.5 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain XG_FTase PF03254.13 CEG37643.1 - 0.045 12.4 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase AAA_22 PF13401.6 CEG37645.1 - 2.7e-07 30.9 0.3 1.6e-06 28.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CEG37645.1 - 4e-07 30.6 4.4 1.7e-06 28.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CEG37645.1 - 8.6e-06 25.8 0.0 4.3e-05 23.5 0.0 2.3 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CEG37645.1 - 0.009 16.2 0.6 0.097 12.8 0.0 3.1 4 0 0 4 4 4 1 AAA domain Sec20 PF03908.13 CEG37645.1 - 0.013 15.4 3.0 0.17 11.8 0.2 3.2 2 0 0 2 2 2 0 Sec20 AAA_7 PF12775.7 CEG37645.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CEG37645.1 - 0.074 13.0 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase PP2C PF00481.21 CEG37646.1 - 6.2e-28 98.1 0.5 9.8e-28 97.5 0.5 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG37646.1 - 8.7e-06 25.5 0.5 1.4e-05 24.9 0.5 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C tRNA-synt_1b PF00579.25 CEG37647.1 - 1.3e-94 316.8 0.0 1.6e-50 172.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Lipoprotein_20 PF13942.6 CEG37647.1 - 0.18 11.7 1.3 2 8.3 0.2 2.5 2 1 1 3 3 3 0 YfhG lipoprotein BLOC1_2 PF10046.9 CEG37649.1 - 0.00068 19.9 9.0 0.0048 17.2 4.5 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CEG37649.1 - 0.0018 18.3 7.1 0.0025 17.9 7.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 CEG37649.1 - 0.0034 16.3 9.2 0.004 16.1 9.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CEG37649.1 - 0.004 17.2 13.4 0.0059 16.6 13.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 CEG37649.1 - 0.0048 15.6 6.3 0.0067 15.1 6.3 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A CdvA PF18822.1 CEG37649.1 - 0.0055 16.5 0.4 0.0055 16.5 0.4 2.0 1 1 1 2 2 2 1 CdvA-like coiled-coil domain DUF16 PF01519.16 CEG37649.1 - 0.011 16.3 10.9 0.02 15.3 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 SNAD3 PF18749.1 CEG37649.1 - 0.012 14.8 1.5 0.014 14.6 1.5 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 OmpH PF03938.14 CEG37649.1 - 0.019 15.3 4.5 0.96 9.8 0.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliD_C PF07195.12 CEG37649.1 - 0.019 14.4 7.6 0.042 13.3 7.6 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TolA_bind_tri PF16331.5 CEG37649.1 - 0.026 14.6 5.4 0.18 11.9 0.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation MPS2 PF17060.5 CEG37649.1 - 0.032 13.5 6.5 0.086 12.1 6.5 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4618 PF15397.6 CEG37649.1 - 0.034 13.6 12.1 0.13 11.6 11.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.12 CEG37649.1 - 0.042 13.9 8.1 0.13 12.3 7.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.13 CEG37649.1 - 0.044 13.6 8.5 0.064 13.1 8.5 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF4407 PF14362.6 CEG37649.1 - 0.055 12.8 2.2 0.082 12.2 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1465 PF07323.12 CEG37649.1 - 0.065 13.1 4.4 0.51 10.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) HrpB7 PF09486.10 CEG37649.1 - 0.075 13.4 4.0 0.15 12.4 4.0 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Tropomyosin_1 PF12718.7 CEG37649.1 - 0.079 13.1 14.9 0.48 10.6 15.0 2.0 1 1 0 1 1 1 0 Tropomyosin like HTH_34 PF13601.6 CEG37649.1 - 0.09 13.0 0.7 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF4709 PF15821.5 CEG37649.1 - 0.092 13.0 8.2 0.13 12.5 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) DUF4795 PF16043.5 CEG37649.1 - 0.095 12.3 10.9 0.22 11.1 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF2703 PF10865.8 CEG37649.1 - 0.096 12.9 3.6 7.4 6.8 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Prominin PF05478.11 CEG37649.1 - 0.11 10.4 8.7 0.12 10.3 8.7 1.0 1 0 0 1 1 1 0 Prominin DUF848 PF05852.11 CEG37649.1 - 0.11 12.6 7.4 0.11 12.7 5.6 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Trimer_CC PF08954.11 CEG37649.1 - 0.12 12.0 0.0 0.12 12.0 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif CorA PF01544.18 CEG37649.1 - 0.13 11.6 3.7 0.14 11.4 3.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HTH_Mga PF08280.11 CEG37649.1 - 0.23 11.5 5.0 5.9 7.0 1.1 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain WXG100 PF06013.12 CEG37649.1 - 0.24 11.7 3.6 2.6 8.3 0.1 2.5 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Spc29 PF17082.5 CEG37649.1 - 0.25 11.1 6.0 14 5.4 6.0 2.0 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF730 PF05325.11 CEG37649.1 - 0.26 11.3 2.3 1.4 9.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF730) COG2 PF06148.11 CEG37649.1 - 0.29 11.2 9.4 0.66 10.1 9.3 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.6 CEG37649.1 - 0.29 11.2 7.6 2.1 8.4 7.5 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 AKNA PF12443.8 CEG37649.1 - 0.3 11.8 8.4 1.3 9.8 2.6 2.6 1 1 2 3 3 3 0 AT-hook-containing transcription factor DUF1451 PF07295.11 CEG37649.1 - 0.33 11.0 6.6 0.18 11.9 4.4 1.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF4988 PF16378.5 CEG37649.1 - 0.37 10.5 4.1 3.5 7.3 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function Syntaxin-6_N PF09177.11 CEG37649.1 - 0.43 11.2 9.0 0.2 12.2 1.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 CEG37649.1 - 0.51 10.6 8.3 1.6 9.0 3.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 CEG37649.1 - 0.64 10.5 9.4 5.1 7.6 3.6 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 CEG37649.1 - 0.71 8.7 5.2 0.78 8.6 5.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CEG37649.1 - 0.76 9.3 6.2 0.91 9.0 6.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.11 CEG37649.1 - 0.79 9.9 13.5 2.6 8.2 7.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 CEG37649.1 - 0.89 8.9 8.8 1 8.7 8.8 1.0 1 0 0 1 1 1 0 FAM76 protein FlxA PF14282.6 CEG37649.1 - 0.93 9.5 11.3 2.6 8.1 5.4 2.1 2 0 0 2 2 2 0 FlxA-like protein YjcZ PF13990.6 CEG37649.1 - 0.94 8.8 6.4 1.8 7.9 1.1 2.0 1 1 1 2 2 2 0 YjcZ-like protein Prefoldin_2 PF01920.20 CEG37649.1 - 1.2 9.1 13.8 23 5.0 13.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF1818 PF08848.11 CEG37649.1 - 1.3 9.2 6.4 8.2 6.6 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1818) UPF0449 PF15136.6 CEG37649.1 - 1.5 9.3 9.7 2 8.9 0.5 2.3 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 PspB PF06667.12 CEG37649.1 - 1.7 8.7 4.5 3.3 7.8 0.1 2.3 1 1 2 3 3 3 0 Phage shock protein B DASH_Dam1 PF08653.10 CEG37649.1 - 2 8.3 5.3 27 4.7 0.1 3.1 1 1 1 2 2 2 0 DASH complex subunit Dam1 Swi5 PF07061.11 CEG37649.1 - 2.3 8.4 8.6 6.7 6.9 2.8 2.4 2 0 0 2 2 2 0 Swi5 SlyX PF04102.12 CEG37649.1 - 3.2 8.4 11.9 7.9 7.2 5.4 2.3 1 1 1 2 2 2 0 SlyX Rho_Binding PF08912.11 CEG37649.1 - 3.5 8.5 14.1 11 6.9 6.0 2.3 1 1 1 2 2 2 0 Rho Binding Spc24 PF08286.11 CEG37649.1 - 7.8 6.8 12.9 12 6.2 1.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tetraspanin PF00335.20 CEG37650.1 - 4.1e-07 30.0 4.9 6.5e-07 29.3 4.9 1.4 1 0 0 1 1 1 1 Tetraspanin family DUF2892 PF11127.8 CEG37650.1 - 4.9 7.3 6.3 0.61 10.2 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Thioredoxin PF00085.20 CEG37652.1 - 1.8e-07 31.1 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Tetraspanin PF00335.20 CEG37652.1 - 0.0097 15.6 8.8 0.0097 15.6 8.8 1.9 1 1 0 2 2 2 1 Tetraspanin family RXLR_WY PF18634.1 CEG37653.1 - 0.16 11.9 0.5 6.5 6.8 0.1 2.5 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain LRR_6 PF13516.6 CEG37655.1 - 1.1e-27 93.6 23.0 2.6e-05 23.9 0.2 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 CEG37655.1 - 1.3e-14 54.0 6.6 0.0017 18.7 0.1 5.9 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG37655.1 - 2e-09 36.7 1.7 7.1 7.6 0.0 8.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 CEG37655.1 - 7e-07 28.9 20.4 0.059 13.1 5.2 6.9 2 1 5 7 7 7 5 Leucine rich repeat DUF1515 PF07439.11 CEG37655.1 - 0.16 12.0 1.6 0.68 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Ysc84 PF04366.12 CEG37656.1 - 2.5e-35 121.0 0.7 5.7e-35 119.9 0.7 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator PGM_PMM_I PF02878.16 CEG37656.1 - 1.2e-17 64.0 0.1 2.9e-07 30.3 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I FYVE PF01363.21 CEG37656.1 - 6.9e-12 45.3 2.4 6.9e-12 45.3 2.4 2.4 2 0 0 2 2 2 1 FYVE zinc finger PGM_PMM_IV PF00408.20 CEG37656.1 - 9.2e-11 41.8 0.1 3.5e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CEG37656.1 - 2.9e-06 27.5 0.0 8.8e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CEG37656.1 - 0.001 19.7 0.0 0.0034 18.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1677 PF07911.13 CEG37656.1 - 0.24 11.8 2.3 0.62 10.5 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) HypA PF01155.19 CEG37656.1 - 0.26 11.3 6.3 3.3 7.8 0.5 2.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_2 PF14445.6 CEG37656.1 - 0.36 11.0 3.9 1 9.6 3.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 OST3_OST6 PF04756.13 CEG37657.1 - 2.1e-11 43.7 6.8 6e-11 42.2 7.3 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family DUF608 PF04685.13 CEG37658.1 - 0.12 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region VitD-bind_III PF09164.10 CEG37660.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.6 1 1 0 1 1 1 0 Vitamin D binding protein, domain III TMEM71 PF15121.6 CEG37660.1 - 0.097 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 TMEM71 protein family Elicitin PF00964.17 CEG37662.1 - 5.8e-16 58.4 7.1 1.6e-15 56.9 7.1 1.8 1 0 0 1 1 1 1 Elicitin Mucin-like PF16058.5 CEG37662.1 - 0.0021 18.1 20.9 0.0021 18.1 20.9 1.8 2 0 0 2 2 2 1 Mucin-like RXLR_WY PF18634.1 CEG37665.1 - 0.00097 19.0 0.3 0.0028 17.5 0.3 1.8 1 0 0 1 1 1 1 RXLR phytopathogen effector protein WY-domain DUF2407_C PF13373.6 CEG37668.1 - 0.02 15.0 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain RXLR_WY PF18634.1 CEG37669.1 - 0.84 9.6 0.1 0.84 9.6 0.1 2.8 3 0 0 3 3 3 0 RXLR phytopathogen effector protein WY-domain RXLR_WY PF18634.1 CEG37672.1 - 0.084 12.8 0.1 49 4.0 0.0 3.3 3 0 0 3 3 3 0 RXLR phytopathogen effector protein WY-domain TMEM154 PF15102.6 CEG37673.1 - 0.081 12.8 2.2 0.19 11.7 0.5 1.9 1 1 1 2 2 2 0 TMEM154 protein family PHA_synth_III_E PF09712.10 CEG37674.1 - 0.0053 15.9 7.0 0.0059 15.7 7.0 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Flu_NS2 PF00601.19 CEG37674.1 - 0.037 14.3 1.4 0.05 13.9 0.8 1.5 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) OTCace_N PF02729.21 CEG37674.1 - 0.041 13.9 0.4 0.049 13.7 0.4 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain zf-C2H2_12 PF18658.1 CEG37674.1 - 0.05 13.2 0.9 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type WXG100 PF06013.12 CEG37674.1 - 0.15 12.4 8.6 0.11 12.8 7.3 1.4 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Retrotrans_gag PF03732.17 CEG37675.1 - 0.0001 22.5 0.3 0.00023 21.4 0.3 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 CEG37675.1 - 0.031 14.0 0.3 0.087 12.6 0.3 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 CEG37676.1 - 1.2e-26 93.0 0.0 1.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEG37676.1 - 3.5e-17 62.3 0.0 6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEG37677.1 - 3.1e-16 59.2 0.9 4.7e-16 58.6 0.9 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain Kinesin PF00225.23 CEG37679.1 - 1e-105 353.4 1.8 1.2e-105 353.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG37679.1 - 4.5e-20 72.1 0.0 1.8e-19 70.2 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding TPR_MLP1_2 PF07926.12 CEG37679.1 - 0.00087 19.4 13.0 0.00087 19.4 13.0 8.0 5 1 3 8 8 8 1 TPR/MLP1/MLP2-like protein AvrLm4-7 PF18661.1 CEG37679.1 - 0.77 10.8 3.7 1.6 9.8 1.2 2.8 2 0 0 2 2 2 0 Avirulence Effector AvrLm4-7 DASH_Dad4 PF08650.10 CEG37679.1 - 1.3 9.1 6.3 3.9 7.5 0.3 4.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF1843 PF08898.10 CEG37679.1 - 1.6 9.3 9.7 2 9.0 0.9 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Glyco_trans_1_2 PF13524.6 CEG37679.1 - 4 7.9 10.4 3.8 8.0 2.2 3.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Dzip-like_N PF13815.6 CEG37682.1 - 4.6e-36 123.4 3.9 4.6e-36 123.4 3.9 4.7 4 1 1 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Ribosomal_S3_C PF00189.20 CEG37682.1 - 0.0094 16.4 0.1 0.032 14.7 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain zf-C2H2 PF00096.26 CEG37682.1 - 0.028 14.9 0.4 0.071 13.6 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEG37682.1 - 0.04 14.2 0.5 0.14 12.5 0.5 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FGAR-AT_linker PF18072.1 CEG37682.1 - 0.05 14.1 2.5 4.1 8.0 0.0 3.9 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain IQ PF00612.27 CEG37682.1 - 0.087 12.7 0.1 0.087 12.7 0.1 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif zf-C2H2_4 PF13894.6 CEG37682.1 - 0.13 13.2 0.6 0.5 11.3 0.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2935 PF11155.8 CEG37682.1 - 7.6 6.9 19.6 1.3 9.3 2.4 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF2935) RVT_1 PF00078.27 CEG37684.1 - 3.5e-21 75.7 0.1 5.5e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BrnT_toxin PF04365.13 CEG37685.1 - 0.086 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Tho2 PF11262.8 CEG37686.1 - 2.4e-79 266.7 0.2 5.6e-79 265.5 0.2 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CEG37686.1 - 1.4e-64 218.9 0.9 3e-41 141.8 0.3 3.3 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CEG37686.1 - 4.5e-29 100.3 0.1 1.7e-28 98.5 0.1 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Acyl_transf_1 PF00698.21 CEG37687.1 - 4.4e-29 102.0 0.4 5.1e-29 101.8 0.4 1.0 1 0 0 1 1 1 1 Acyl transferase domain BAR PF03114.18 CEG37688.1 - 1.5e-10 41.1 4.4 2.1e-10 40.7 4.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CEG37688.1 - 0.00065 19.5 9.5 0.00098 18.9 9.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Occludin_ELL PF07303.13 CEG37688.1 - 0.038 14.7 4.5 0.87 10.4 0.9 2.8 2 1 1 3 3 3 0 Occludin homology domain SlyX PF04102.12 CEG37688.1 - 0.044 14.4 2.1 1.3 9.7 0.7 2.6 2 0 0 2 2 2 0 SlyX DUF3879 PF12995.7 CEG37688.1 - 0.22 11.2 0.9 0.34 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) 3HCDH_N PF02737.18 CEG37688.1 - 0.26 11.1 2.0 0.3 11.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4745 PF15923.5 CEG37688.1 - 0.34 10.9 6.2 0.084 12.9 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Tape_meas_lam_C PF09718.10 CEG37688.1 - 0.39 10.9 3.7 0.23 11.6 0.7 2.1 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) FapA PF03961.13 CEG37688.1 - 1.4 7.4 3.8 6.4 5.3 3.8 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2802 PF10975.8 CEG37688.1 - 7.1 6.8 12.0 0.3 11.3 1.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) AAR2 PF05282.11 CEG37689.1 - 1.2e-74 251.8 2.1 4.7e-38 131.5 1.1 2.2 2 0 0 2 2 2 2 AAR2 protein DUF402 PF04167.13 CEG37689.1 - 0.053 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF402) MIF4G PF02854.19 CEG37690.1 - 4.4e-41 140.9 4.0 9.6e-26 90.7 0.5 2.2 2 0 0 2 2 2 2 MIF4G domain DUF966 PF06136.13 CEG37690.1 - 0.0053 16.5 13.7 0.0094 15.7 13.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Abhydrolase_6 PF12697.7 CEG37692.1 - 3.5e-24 86.6 0.0 4.6e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEG37692.1 - 4.4e-11 42.9 0.3 3.5e-10 40.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG37692.1 - 2.7e-09 36.6 0.3 4.4e-09 35.9 0.3 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CEG37692.1 - 6.9e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CEG37692.1 - 0.0025 17.6 0.6 0.0072 16.1 0.1 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 CEG37692.1 - 0.0086 15.9 0.5 0.24 11.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 CEG37692.1 - 0.0095 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CEG37692.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 CEG37692.1 - 0.021 13.7 0.3 0.058 12.3 0.3 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme CD4-extracel PF09191.10 CEG37692.1 - 0.056 13.9 0.2 0.14 12.6 0.2 1.5 1 1 0 1 1 1 0 CD4, extracellular Abhydrolase_5 PF12695.7 CEG37692.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CEG37692.1 - 0.14 12.2 0.2 0.58 10.2 0.2 2.0 1 1 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 CEG37692.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 CEG37692.1 - 0.28 11.0 1.6 3.4 7.4 1.6 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Nuc_sug_transp PF04142.15 CEG37693.1 - 9.9e-82 274.6 21.1 1.2e-81 274.4 21.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CEG37693.1 - 1.2e-08 34.5 18.5 1.8e-08 33.9 18.5 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CEG37693.1 - 3.2e-06 26.6 10.8 3.2e-06 26.6 10.8 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 CEG37693.1 - 0.00014 20.9 4.1 0.00014 20.9 4.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CEG37693.1 - 0.0014 18.8 24.7 0.0022 18.2 5.5 3.3 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 CEG37693.1 - 0.0021 17.5 5.3 0.0021 17.5 5.3 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Metallophos_2 PF12850.7 CEG37694.1 - 5.4e-24 85.2 0.3 6.7e-24 84.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CEG37694.1 - 1.6e-05 25.6 0.4 0.14 12.6 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase BMFP PF04380.13 CEG37694.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity ACT_7 PF13840.6 CEG37696.1 - 3.4e-25 87.6 0.0 7.5e-16 57.7 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 CEG37696.1 - 0.00024 20.9 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Pex24p PF06398.11 CEG37697.1 - 0.0019 17.2 0.0 0.0019 17.2 0.0 2.4 3 0 0 3 3 3 1 Integral peroxisomal membrane peroxin HALZ PF02183.18 CEG37697.1 - 0.22 11.8 0.1 0.22 11.8 0.1 4.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper CD52 PF15116.6 CEG37697.1 - 0.34 11.0 3.6 1.3 9.1 3.6 2.0 1 0 0 1 1 1 0 CAMPATH-1 antigen DUF1319 PF07028.11 CEG37697.1 - 1.5 9.1 17.4 1.4 9.1 1.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) Nuc_sug_transp PF04142.15 CEG37698.1 - 7.7e-50 169.8 18.9 1.3e-49 169.1 18.9 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CEG37698.1 - 0.0043 17.2 8.8 0.0043 17.2 8.8 2.6 2 1 0 2 2 2 1 EamA-like transporter family DUF2859 PF11072.8 CEG37698.1 - 0.29 10.9 2.4 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Chorein_N PF12624.7 CEG37699.1 - 5.2e-23 81.4 0.1 6.2e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 RVT_2 PF07727.14 CEG37700.1 - 1.5e-18 67.3 0.0 2.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2009 PF09418.10 CEG37702.1 - 0.14 11.2 6.9 0.27 10.2 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Ras PF00071.22 CEG37703.1 - 2.1e-20 73.0 0.0 4.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Ras family EF_assoc_2 PF08356.12 CEG37703.1 - 9.2e-12 44.8 0.0 2.5e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 CEG37703.1 - 4.9e-11 42.9 0.0 2.7e-10 40.5 0.0 2.3 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_5 PF13202.6 CEG37703.1 - 6e-09 35.0 2.6 0.0012 18.3 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG37703.1 - 2.2e-08 33.3 2.0 0.00051 19.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEG37703.1 - 2.8e-08 32.8 1.9 0.00013 21.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF_assoc_1 PF08355.12 CEG37703.1 - 9.2e-07 28.4 0.0 4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF-hand_7 PF13499.6 CEG37703.1 - 1.6e-06 28.5 0.1 0.0074 16.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEG37703.1 - 2.1e-06 27.5 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 CEG37703.1 - 7.8e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG37703.1 - 0.00012 22.1 0.1 0.0039 17.3 0.0 2.9 2 1 1 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG37703.1 - 0.0047 16.5 0.3 0.03 13.9 0.1 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SPARC_Ca_bdg PF10591.9 CEG37703.1 - 0.0059 16.9 0.3 1.5 9.2 0.1 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF608 PF04685.13 CEG37703.1 - 0.047 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region RsgA_GTPase PF03193.16 CEG37703.1 - 0.049 13.5 0.5 0.42 10.5 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase Bile_Hydr_Trans PF04775.14 CEG37703.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region ATPase_2 PF01637.18 CEG37703.1 - 0.082 12.8 0.1 1 9.2 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea HTH_19 PF12844.7 CEG37704.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4007 PF13182.6 CEG37704.1 - 0.17 11.0 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) DSPn PF14671.6 CEG37707.1 - 2.2e-41 141.6 0.0 5.7e-41 140.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CEG37707.1 - 3.1e-15 56.1 0.0 2e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG37707.1 - 6.5e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEG37707.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate PRO8NT PF08082.11 CEG37707.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Y_phosphatase3 PF13350.6 CEG37707.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family 6PGD PF00393.19 CEG37712.1 - 9.2e-127 422.4 0.0 1.1e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEG37712.1 - 3.1e-46 157.4 0.0 4.7e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEG37712.1 - 0.0063 17.1 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CEG37712.1 - 0.0089 15.9 0.0 0.022 14.6 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEG37712.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phage_portal PF04860.12 CEG37712.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein adh_short PF00106.25 CEG37712.1 - 0.19 11.1 0.0 0.47 9.9 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase CAP PF00188.26 CEG37713.1 - 2.6e-19 70.3 1.1 5.9e-19 69.1 1.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 CEG37713.1 - 2.1e-05 24.3 7.1 2.1e-05 24.3 7.1 2.4 2 0 0 2 2 2 1 PAN domain Orn_Arg_deC_N PF02784.16 CEG37715.1 - 1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEG37715.1 - 7.1e-11 42.2 0.0 1.6e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain EMP24_GP25L PF01105.24 CEG37716.1 - 4.3e-20 72.4 1.1 6.9e-12 45.7 0.2 2.3 2 1 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Peptidase_S24 PF00717.23 CEG37717.1 - 2.7e-10 40.0 0.0 3.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CEG37717.1 - 7.8e-07 29.0 0.0 0.00048 19.9 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Complex1_LYR PF05347.15 CEG37718.1 - 9.3e-13 48.0 0.1 1.4e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CEG37718.1 - 3.1e-07 30.9 0.1 4.3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 CEG37718.1 - 0.00016 22.3 0.2 0.00021 22.0 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_2 PF13240.6 CEG37718.1 - 0.0013 18.4 2.8 0.0013 18.4 2.8 1.6 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 CEG37718.1 - 0.0016 18.4 0.7 0.0016 18.4 0.7 1.7 2 0 0 2 2 2 1 Double zinc ribbon ADK_lid PF05191.14 CEG37718.1 - 0.0063 16.5 0.4 0.013 15.4 0.4 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 CEG37718.1 - 0.027 13.9 1.8 0.027 13.9 1.8 2.1 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 CEG37718.1 - 0.039 14.1 4.6 0.041 14.0 2.6 2.0 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like NinF PF05810.12 CEG37718.1 - 0.051 13.5 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 NinF protein HypA PF01155.19 CEG37718.1 - 0.11 12.6 2.6 0.077 13.0 1.6 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CLP_protease PF00574.23 CEG37720.1 - 2.8e-80 268.5 0.0 3.3e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Clp protease PGAP1 PF07819.13 CEG37720.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-HIT PF04438.16 CEG37721.1 - 8.1e-12 44.8 12.3 1.2e-11 44.2 12.3 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CEG37721.1 - 0.054 13.6 11.2 0.095 12.8 11.2 1.5 1 0 0 1 1 1 0 MYND finger Cyclin_N2 PF16500.5 CEG37721.1 - 0.065 14.0 1.1 0.079 13.7 1.1 1.1 1 0 0 1 1 1 0 N-terminal region of cyclin_N Cylicin_N PF15241.6 CEG37721.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Cylicin N-terminus PolC_DP2 PF03833.13 CEG37721.1 - 0.17 9.7 5.2 0.18 9.6 5.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 CEG37721.1 - 0.23 11.7 10.8 0.38 10.9 10.8 1.5 1 0 0 1 1 1 0 B-box zinc finger PMI_typeI PF01238.21 CEG37722.1 - 3.4e-108 362.2 0.0 4.4e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I bact-PGI_C PF10432.9 CEG37722.1 - 0.069 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Pkinase PF00069.25 CEG37723.1 - 8.3e-62 208.9 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37723.1 - 3.1e-45 154.5 0.0 8.9e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG37723.1 - 1e-05 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG37723.1 - 8.3e-05 21.5 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Ndufs5 PF10200.9 CEG37723.1 - 0.0012 19.0 3.2 0.0097 16.1 1.0 2.4 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 CEG37723.1 - 0.0066 16.6 5.5 0.015 15.4 5.5 1.6 1 0 0 1 1 1 1 CHCH domain APH PF01636.23 CEG37723.1 - 0.11 12.4 0.0 3.7 7.4 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family NiFeSe_Hases PF00374.19 CEG37723.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Cmc1 PF08583.10 CEG37723.1 - 0.29 11.2 3.5 0.7 10.0 3.5 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CEG37723.1 - 8.4 6.8 7.8 35 4.8 1.9 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Glyco_hydro_12 PF01670.16 CEG37727.1 - 4.5e-09 36.6 0.1 5.5e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 TPR_2 PF07719.17 CEG37730.1 - 2.6e-09 36.5 5.5 0.0006 19.7 1.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 CEG37730.1 - 7.8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_8 PF13181.6 CEG37730.1 - 2.2e-07 30.5 5.5 0.0024 17.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37730.1 - 5.4e-07 29.2 7.4 0.0019 17.9 2.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37730.1 - 8.2e-06 26.2 5.5 0.008 16.7 0.1 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG37730.1 - 1.6e-05 24.5 3.2 0.0014 18.3 1.2 3.0 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 CEG37730.1 - 2.2e-05 24.9 0.2 0.13 13.2 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG37730.1 - 2.4e-05 24.5 3.4 0.062 13.6 0.4 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG37730.1 - 0.0012 19.5 0.2 0.045 14.4 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG37730.1 - 0.0018 18.3 7.7 0.0059 16.6 0.5 3.1 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CEG37730.1 - 0.0067 16.3 4.7 0.35 10.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG37730.1 - 0.0087 16.0 0.5 0.18 11.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG37730.1 - 0.017 15.7 1.4 7.5 7.4 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CEG37730.1 - 0.023 14.7 0.8 0.023 14.7 0.8 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CEG37730.1 - 0.026 14.8 2.8 0.58 10.4 2.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Death PF00531.22 CEG37730.1 - 0.043 14.0 1.7 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Death domain CAP_C PF08603.11 CEG37730.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal SHNi-TPR PF10516.9 CEG37730.1 - 0.08 12.4 0.6 0.44 10.0 0.1 2.3 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.6 CEG37730.1 - 0.081 13.3 1.7 0.91 10.0 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat SPO22 PF08631.10 CEG37730.1 - 0.18 11.3 6.8 0.34 10.3 1.7 2.3 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.9 CEG37730.1 - 0.64 9.7 6.3 1.3 8.7 6.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Alkyl_sulf_dimr PF14863.6 CEG37730.1 - 2 8.9 5.5 6.7 7.2 0.3 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Dynamin_M PF01031.20 CEG37731.1 - 2e-39 135.5 1.1 5.4e-28 98.0 0.2 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CEG37731.1 - 1.5e-37 129.3 0.4 3.5e-37 128.0 0.4 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CEG37731.1 - 3.1e-08 33.7 2.0 5.1e-08 33.0 0.3 2.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GED PF02212.18 CEG37731.1 - 7.4e-06 26.0 4.5 2.6e-05 24.3 0.4 3.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain ABC_tran PF00005.27 CEG37731.1 - 0.0034 17.9 0.2 0.015 15.8 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 CEG37731.1 - 0.01 16.2 1.3 0.15 12.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CEG37731.1 - 0.019 14.7 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CEG37731.1 - 0.025 14.8 0.2 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ImcF-related_N PF14331.6 CEG37731.1 - 0.028 13.8 3.1 19 4.5 0.1 4.0 4 0 0 4 4 4 0 ImcF-related N-terminal domain FeoB_N PF02421.18 CEG37731.1 - 0.047 13.2 0.4 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 CEG37731.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4404 PF14357.6 CEG37731.1 - 2.3 8.9 8.5 0.7 10.6 0.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) Pectinesterase PF01095.19 CEG37732.1 - 5.6e-65 219.0 18.7 1.3e-32 112.7 4.7 2.4 2 0 0 2 2 2 2 Pectinesterase MOSP_C PF02722.15 CEG37732.1 - 0.018 14.8 0.2 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Major Outer Sheath Protein C-terminal domain DUF4905 PF16248.5 CEG37732.1 - 0.026 14.4 0.2 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4905) DUF3618 PF12277.8 CEG37732.1 - 0.064 13.5 0.2 14 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) BpuJI_N PF11564.8 CEG37732.1 - 0.079 12.2 0.8 11 5.2 0.0 2.6 2 0 0 2 2 2 0 Restriction endonuclease BpuJI - N terminal Lar_N PF09861.9 CEG37732.1 - 0.1 11.7 1.0 11 5.1 0.1 2.3 2 0 0 2 2 2 0 Lactate racemase N-terminal domain ATS3 PF06232.11 CEG37732.1 - 0.21 11.5 1.7 15 5.5 0.2 3.4 2 2 2 4 4 4 0 Embryo-specific protein 3, (ATS3) MIF PF01187.18 CEG37734.1 - 8.9e-23 80.8 0.4 9.8e-23 80.6 0.4 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CEG37734.1 - 0.084 12.8 0.0 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme PRA-CH PF01502.18 CEG37735.1 - 5e-27 93.5 0.1 1.1e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CEG37735.1 - 4.3e-11 43.1 0.8 9.1e-11 42.1 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase PrpR_N PF06506.11 CEG37735.1 - 0.039 13.5 0.5 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator SF3a60_bindingd PF12108.8 CEG37735.1 - 0.35 10.8 0.9 0.72 9.8 0.9 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain UCR_UQCRX_QCR9 PF05365.12 CEG37736.1 - 1.1e-14 54.0 0.2 1.5e-14 53.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF1115 PF06544.12 CEG37736.1 - 0.1 12.7 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) NOA36 PF06524.12 CEG37736.1 - 1.7 7.9 13.3 1.9 7.7 13.3 1.1 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 CEG37736.1 - 1.7 6.5 5.2 1.8 6.4 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Astro_capsid_p PF12226.8 CEG37736.1 - 2.7 7.1 7.7 2.6 7.1 7.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 CEG37736.1 - 4.6 5.3 12.0 4.6 5.3 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CEG37736.1 - 8.6 4.5 10.3 9.1 4.4 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_A51 PF04948.13 CEG37737.1 - 0.18 10.6 0.2 0.27 10.0 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein RNA_pol_Rpb4 PF03874.16 CEG37738.1 - 2.3e-16 60.2 2.4 3.7e-16 59.6 2.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 RRM_1 PF00076.22 CEG37739.1 - 1.2e-38 130.7 0.6 7e-16 57.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CEG37739.1 - 5.1e-12 46.7 0.4 1.8e-11 45.0 0.4 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CEG37739.1 - 0.00031 20.5 0.0 2.7 7.9 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RL PF17797.1 CEG37739.1 - 0.013 15.5 0.0 0.085 12.8 0.0 2.5 3 0 0 3 3 3 0 RL domain RRM_7 PF16367.5 CEG37739.1 - 0.017 15.3 0.1 2.2 8.4 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif Cas_Cas2CT1978 PF09707.10 CEG37739.1 - 0.081 13.0 0.0 2 8.6 0.0 2.6 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) FAM76 PF16046.5 CEG37739.1 - 0.28 10.5 13.6 0.46 9.8 13.6 1.3 1 0 0 1 1 1 0 FAM76 protein RSRP PF17069.5 CEG37739.1 - 1.3 8.5 54.0 2.5 7.6 54.0 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.9 CEG37739.1 - 4.3 6.1 20.0 6.8 5.4 20.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_1 PF00515.28 CEG37740.1 - 1.4e-13 50.0 2.6 4.2e-06 26.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37740.1 - 9.5e-13 47.2 0.4 0.0093 16.0 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG37740.1 - 1.9e-06 27.9 3.1 2e-06 27.8 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37740.1 - 1.6e-05 25.4 1.1 8.9e-05 22.9 1.1 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG37740.1 - 4.9e-05 23.2 4.6 0.69 10.3 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG37740.1 - 7.3e-05 22.8 3.0 0.0022 18.0 0.1 3.0 2 1 1 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CEG37740.1 - 0.00038 21.0 1.2 0.21 12.3 0.5 3.3 1 1 0 2 2 2 1 Tetratricopeptide repeat Arm PF00514.23 CEG37740.1 - 0.0018 18.2 9.6 12 6.2 0.1 6.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat TPR_17 PF13431.6 CEG37740.1 - 0.0024 18.1 0.7 0.16 12.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37740.1 - 0.0035 18.0 6.0 0.058 14.2 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Mistic PF11458.8 CEG37740.1 - 0.0059 16.5 0.8 0.018 15.0 0.2 2.2 2 0 0 2 2 2 1 Membrane-integrating protein Mistic TPR_11 PF13414.6 CEG37740.1 - 0.021 14.5 3.0 1.9 8.2 0.0 3.3 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 CEG37740.1 - 0.2 12.0 4.4 1.7 9.0 0.4 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat Hemolysin_N PF12563.8 CEG37740.1 - 0.59 9.7 3.9 8.7 5.9 0.0 3.2 3 0 0 3 3 3 0 Hemolytic toxin N terminal Tctex-1 PF03645.13 CEG37741.1 - 5.1e-27 94.1 0.3 5.8e-27 93.9 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 CEG37741.1 - 0.019 14.6 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family OspD PF03207.13 CEG37741.1 - 0.034 13.5 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) UQ_con PF00179.26 CEG37742.1 - 3.9e-43 146.5 0.0 4.4e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEG37742.1 - 0.00026 20.7 0.0 0.00032 20.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Proteasome PF00227.26 CEG37743.1 - 1.4e-34 119.2 0.1 1.9e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Tim17 PF02466.19 CEG37744.1 - 1.2e-29 103.0 5.5 1.4e-29 102.7 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.6 CEG37744.1 - 0.0035 17.4 0.1 0.031 14.3 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4235) Sec20 PF03908.13 CEG37745.1 - 2.9e-07 30.3 0.7 5.5e-07 29.4 0.7 1.5 1 0 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 CEG37745.1 - 5.9e-06 26.5 2.1 1.2e-05 25.4 2.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 CEG37745.1 - 0.015 15.2 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) KxDL PF10241.9 CEG37745.1 - 0.023 14.9 4.5 0.032 14.5 1.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Peptidase_C25 PF01364.18 CEG37745.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 DASH_Duo1 PF08651.10 CEG37745.1 - 0.086 12.6 0.3 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 Spc7 PF08317.11 CEG37745.1 - 0.38 9.6 4.3 1.3 7.8 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein LUC7 PF03194.15 CEG37745.1 - 0.42 10.3 4.1 0.82 9.3 3.8 1.7 1 1 0 1 1 1 0 LUC7 N_terminus Ank_2 PF12796.7 CEG37746.1 - 9.7e-20 71.0 0.8 1e-09 38.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEG37746.1 - 2.7e-16 59.2 1.8 2.1e-05 24.7 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CEG37746.1 - 5e-13 48.0 0.1 0.0067 16.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CEG37746.1 - 1.2e-12 47.8 0.2 0.0015 18.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG37746.1 - 2.3e-11 44.0 0.1 0.00023 21.6 0.1 2.9 1 1 1 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 CEG37746.1 - 2.7e-07 30.9 0.0 6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG37746.1 - 1.1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AnkUBD PF18418.1 CEG37746.1 - 0.0097 16.0 0.0 8 6.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin ubiquitin-binding domain Pns11_12 PF17464.2 CEG37746.1 - 0.044 13.5 0.5 0.092 12.5 0.5 1.5 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Eaf7 PF07904.13 CEG37746.1 - 0.096 13.1 2.0 0.2 12.1 2.0 1.5 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Sugar_tr PF00083.24 CEG37748.1 - 4e-96 322.6 19.9 4.9e-96 322.3 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG37748.1 - 1e-28 100.3 50.6 6.2e-25 87.9 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CEG37748.1 - 0.17 10.2 10.1 1.7 6.9 0.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector CytB6-F_Fe-S PF08802.10 CEG37748.1 - 0.18 11.8 4.5 1.5 8.9 0.4 2.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DUF4084 PF13321.6 CEG37748.1 - 0.29 10.7 7.4 0.31 10.6 6.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4084) DUF2583 PF10762.9 CEG37748.1 - 1.4 9.4 8.7 1.3 9.5 3.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Sugar_tr PF00083.24 CEG37751.1 - 2.1e-86 290.6 28.0 8.6e-86 288.6 28.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG37751.1 - 1.1e-23 83.7 35.0 1.1e-23 83.7 35.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEG37751.1 - 2.8e-05 22.8 3.2 2.8e-05 22.8 3.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TssN PF17555.2 CEG37751.1 - 0.0047 16.4 0.5 0.0047 16.4 0.5 2.2 3 0 0 3 3 3 1 Type VI secretion system, TssN SET PF00856.28 CEG37753.1 - 5.5e-11 43.1 0.0 1.3e-10 42.0 0.0 1.7 2 0 0 2 2 2 1 SET domain UPF0113 PF03657.13 CEG37753.1 - 0.065 13.5 0.0 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 UPF0113 PUA domain FUR PF01475.19 CEG37753.1 - 0.14 12.4 3.4 0.077 13.1 0.8 1.9 2 0 0 2 2 2 0 Ferric uptake regulator family UBA_4 PF14555.6 CEG37753.1 - 0.21 11.4 0.3 0.6 10.0 0.1 1.9 2 0 0 2 2 2 0 UBA-like domain Pkinase_Tyr PF07714.17 CEG37754.1 - 7.5e-53 179.4 0.0 8.8e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG37754.1 - 5e-50 170.3 0.0 6.3e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEG37754.1 - 0.0044 16.4 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG37754.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEG37754.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPALS PF18178.1 CEG37754.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Sugar_tr PF00083.24 CEG37755.1 - 6e-88 295.7 21.8 7.7e-88 295.3 21.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG37755.1 - 6.1e-22 78.0 27.9 6.1e-22 78.0 27.9 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 CEG37755.1 - 0.00039 19.0 5.7 0.00039 19.0 5.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EF-hand_7 PF13499.6 CEG37758.1 - 2.9e-24 85.3 3.9 5.1e-12 46.1 0.5 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG37758.1 - 7.7e-21 72.0 0.3 0.00021 20.6 0.0 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CEG37758.1 - 2.7e-17 61.2 7.3 0.00015 21.4 0.1 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEG37758.1 - 5.5e-15 54.1 4.2 0.0031 17.0 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEG37758.1 - 1e-13 50.9 1.3 2.5e-05 24.0 0.1 4.0 2 2 2 4 4 4 3 EF-hand domain pair Ank_2 PF12796.7 CEG37758.1 - 4.4e-09 36.8 0.5 0.014 15.9 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) WW PF00397.26 CEG37758.1 - 1.6e-06 28.1 3.0 2.6e-06 27.4 1.5 2.1 2 0 0 2 2 2 1 WW domain Ank_5 PF13857.6 CEG37758.1 - 2.7e-05 24.4 1.3 3.8 7.9 0.0 6.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG37758.1 - 0.0011 19.5 3.3 0.83 10.3 0.0 5.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) EF-hand_4 PF12763.7 CEG37758.1 - 0.0015 18.4 3.2 6.5 6.8 0.1 3.8 2 1 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG37758.1 - 0.0018 18.6 0.0 0.71 10.2 0.0 3.0 3 0 0 3 3 2 1 EF-hand domain Ank_3 PF13606.6 CEG37758.1 - 0.0033 17.8 10.0 3.1 8.7 0.1 7.0 7 0 0 7 7 7 1 Ankyrin repeat IQ PF00612.27 CEG37758.1 - 0.011 15.5 0.1 0.054 13.3 0.1 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_10 PF14788.6 CEG37758.1 - 0.017 15.0 0.1 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 EF hand 3HCDH_N PF02737.18 CEG37759.1 - 1.8e-42 145.2 0.1 2.5e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEG37759.1 - 4.2e-07 29.7 0.3 6.5e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CEG37759.1 - 0.00011 21.6 0.8 0.00019 20.8 0.7 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CEG37759.1 - 0.00033 20.1 0.0 0.00068 19.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 CEG37759.1 - 0.00039 20.1 0.0 0.00043 20.0 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 CEG37759.1 - 0.00056 20.1 0.7 0.014 15.6 0.7 2.2 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 CEG37759.1 - 0.0021 18.3 0.1 0.0053 16.9 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 CEG37759.1 - 0.0032 16.7 0.1 0.0055 16.0 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 CEG37759.1 - 0.0058 16.0 1.5 0.0089 15.4 0.5 1.7 1 1 0 1 1 1 1 ThiF family DUF1188 PF06690.11 CEG37759.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_Gly3P_dh_N PF01210.23 CEG37759.1 - 0.0086 16.1 0.8 0.048 13.6 0.8 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UPF0146 PF03686.13 CEG37759.1 - 0.01 15.7 0.2 0.028 14.3 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0146) F420_oxidored PF03807.17 CEG37759.1 - 0.014 15.9 0.0 0.032 14.8 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 CEG37759.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CEG37759.1 - 0.024 15.2 0.1 0.046 14.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CEG37759.1 - 0.027 14.5 1.1 0.4 10.7 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CEG37759.1 - 0.037 13.6 0.3 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 CEG37759.1 - 0.055 13.1 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 CEG37759.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AdoHcyase_NAD PF00670.21 CEG37759.1 - 0.17 11.9 1.2 0.31 11.1 1.1 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.24 CEG37761.1 - 2e-85 287.4 24.3 2.5e-85 287.0 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG37761.1 - 6.4e-23 81.2 32.7 6.4e-23 81.2 32.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEG37761.1 - 7.2e-06 24.7 3.9 7.2e-06 24.7 3.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2583 PF10762.9 CEG37761.1 - 0.98 9.9 8.2 1.6 9.2 4.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) GST_N_3 PF13417.6 CEG37762.1 - 3.5e-13 49.8 0.0 9.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEG37762.1 - 8.6e-13 48.4 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEG37762.1 - 9.3e-08 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEG37762.1 - 6.9e-06 26.2 0.2 2e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEG37762.1 - 3.1e-05 24.1 0.0 0.00024 21.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEG37762.1 - 0.00043 20.2 0.0 0.00097 19.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CEG37762.1 - 0.012 16.0 0.0 0.2 12.0 0.0 2.4 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CEG37762.1 - 0.037 14.8 0.0 1.1 10.0 0.0 2.8 2 1 0 3 3 3 0 Glutathione S-transferase N-terminal domain FYVE PF01363.21 CEG37763.1 - 1.3e-12 47.7 11.5 3e-12 46.5 11.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG37763.1 - 0.00076 19.7 6.3 0.00076 19.7 6.3 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Vinculin PF01044.19 CEG37763.1 - 1.4 7.1 5.0 2.4 6.3 5.0 1.3 1 0 0 1 1 1 0 Vinculin family Kinesin PF00225.23 CEG37768.1 - 4.8e-118 393.9 0.3 9.8e-118 392.9 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG37768.1 - 5.9e-27 94.4 0.2 2.7e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 CEG37768.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.8 3 1 1 4 4 4 0 AAA domain ZapB PF06005.12 CEG37769.1 - 0.29 11.6 16.9 8.1 7.0 0.4 2.8 1 1 1 2 2 2 0 Cell division protein ZapB CC2-LZ PF16516.5 CEG37769.1 - 0.37 11.2 9.0 0.93 9.9 9.0 1.7 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Seryl_tRNA_N PF02403.22 CEG37769.1 - 0.4 10.9 6.9 1 9.6 6.9 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NRBF2 PF08961.10 CEG37769.1 - 0.73 9.4 7.5 1.3 8.6 7.5 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Exonuc_VII_L PF02601.15 CEG37769.1 - 2.3 7.7 6.9 3.2 7.2 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HALZ PF02183.18 CEG37769.1 - 7.2 6.9 14.4 0.046 14.0 3.7 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper PH PF00169.29 CEG37770.1 - 1.3e-20 73.9 0.1 1.1e-09 38.7 0.1 2.7 2 2 0 2 2 2 2 PH domain PH_11 PF15413.6 CEG37770.1 - 3.1e-10 40.4 1.9 6.2e-06 26.6 0.0 2.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CEG37770.1 - 6.6e-05 23.1 1.5 4.3 7.7 0.1 4.0 3 1 0 4 4 4 2 Pleckstrin homology domain PH_6 PF15406.6 CEG37770.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain CUE PF02845.16 CEG37771.1 - 5.9e-09 35.5 1.1 0.00089 18.9 0.1 3.7 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 CEG37771.1 - 3.4e-07 30.5 0.3 1.3e-06 28.6 0.3 2.0 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 CEG37771.1 - 5.2e-05 22.8 0.1 0.0077 15.8 0.0 2.9 3 0 0 3 3 3 1 DMRTA motif UBA_4 PF14555.6 CEG37771.1 - 0.0025 17.6 0.1 1.3 8.9 0.0 3.3 3 0 0 3 3 3 1 UBA-like domain HOIP-UBA PF16678.5 CEG37771.1 - 0.011 15.7 0.1 0.011 15.7 0.1 2.8 4 0 0 4 4 4 0 HOIP UBA domain pair HBS1_N PF08938.10 CEG37771.1 - 0.044 14.1 0.2 13 6.2 0.0 2.9 2 0 0 2 2 2 0 HBS1 N-terminus zf-RING_2 PF13639.6 CEG37772.1 - 2.9e-10 40.3 6.6 5.2e-10 39.5 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG37772.1 - 4.4e-07 29.6 7.0 8.5e-07 28.7 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG37772.1 - 9.1e-07 28.5 3.9 9.1e-07 28.5 3.9 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CEG37772.1 - 1.3e-06 28.3 4.3 2.2e-06 27.5 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEG37772.1 - 1.4e-06 28.5 4.8 3.3e-06 27.3 4.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEG37772.1 - 2.4e-05 24.1 5.5 4.2e-05 23.3 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEG37772.1 - 6.3e-05 22.9 1.8 0.00015 21.7 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG37772.1 - 9e-05 22.3 5.2 0.00015 21.5 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG37772.1 - 0.00014 21.7 6.2 0.00025 20.9 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG37772.1 - 0.0012 18.4 5.9 0.0026 17.4 5.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CEG37772.1 - 0.0017 18.1 5.1 0.0035 17.1 5.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CEG37772.1 - 0.011 15.8 3.1 0.026 14.6 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CEG37772.1 - 0.037 14.2 3.7 0.093 12.9 3.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 CEG37772.1 - 0.24 11.5 3.5 0.51 10.5 3.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 CEG37772.1 - 0.79 9.9 6.4 1.7 8.8 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 CEG37772.1 - 3.4 7.8 8.0 0.52 10.4 3.5 2.0 2 0 0 2 2 2 0 Zinc-finger Fungal_KA1 PF16797.5 CEG37777.1 - 0.2 11.4 2.2 2.4 7.9 0.2 2.7 2 0 0 2 2 2 0 Fungal kinase associated-1 domain DUF4238 PF14022.6 CEG37777.1 - 0.56 9.7 6.0 8.7 5.8 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) Malate_DH PF12434.8 CEG37777.1 - 6 7.0 7.3 2.3 8.3 0.3 3.0 3 0 0 3 3 3 0 Malate dehydrogenase enzyme rve PF00665.26 CEG37779.1 - 2.6e-06 27.6 0.1 4.2e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DUF5330 PF17264.2 CEG37779.1 - 0.092 12.8 0.0 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5330) Pkinase PF00069.25 CEG37780.1 - 1.9e-50 171.7 0.0 2.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37780.1 - 7.8e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG37780.1 - 1.2e-05 24.9 11.7 0.015 15.1 2.7 2.7 1 1 2 3 3 2 2 Leucine rich repeat LRR_4 PF12799.7 CEG37780.1 - 1.6e-05 25.1 10.6 0.0015 18.9 2.2 3.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Kdo PF06293.14 CEG37780.1 - 0.0034 16.8 1.6 0.0056 16.1 1.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CEG37780.1 - 0.015 14.5 0.1 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase Pkinase_fungal PF17667.1 CEG37780.1 - 0.018 13.8 0.2 0.028 13.2 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 CEG37780.1 - 0.042 13.9 2.8 0.36 11.0 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 CEG37780.1 - 0.063 13.9 5.1 13 6.8 0.1 4.4 3 1 1 4 4 3 0 Leucine Rich Repeat APH PF01636.23 CEG37780.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3377 PF11857.8 CEG37780.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4519 PF15012.6 CEG37780.1 - 0.22 11.7 1.2 0.7 10.1 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Pep3_Vps18 PF05131.14 CEG37781.1 - 9.3e-42 142.4 0.0 3.5e-41 140.5 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CEG37781.1 - 1.9e-12 47.3 4.9 6.3e-09 35.8 0.2 3.6 4 1 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CEG37781.1 - 0.021 15.3 0.0 0.22 12.0 0.0 2.7 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 CEG37781.1 - 0.039 13.7 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger GrpE PF01025.19 CEG37781.1 - 0.31 10.7 4.2 3.9 7.1 0.7 2.5 2 0 0 2 2 2 0 GrpE Prefoldin PF02996.17 CEG37781.1 - 0.48 10.3 5.8 0.065 13.1 0.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CEG37781.1 - 2.2 8.4 12.4 2.9 7.9 0.7 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tektin PF03148.14 CEG37782.1 - 0.029 13.1 1.1 0.066 12.0 1.1 1.6 1 1 0 1 1 1 0 Tektin family Aminotran_3 PF00202.21 CEG37783.1 - 4.7e-122 407.5 0.0 5.7e-122 407.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.25 CEG37784.1 - 0.00046 19.6 0.1 0.0038 16.6 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain ABM PF03992.16 CEG37785.1 - 1.2e-11 44.6 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 CEG37785.1 - 0.0031 18.1 0.0 0.0039 17.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.11 CEG37785.1 - 0.0032 17.7 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Dehydratase_hem PF13816.6 CEG37785.1 - 0.059 12.8 0.1 0.069 12.5 0.1 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Caps_synth_GfcC PF06251.11 CEG37786.1 - 0.016 14.9 2.1 0.02 14.5 2.1 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Uds1 PF15456.6 CEG37786.1 - 0.016 15.4 2.1 0.028 14.6 2.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DUF4509 PF14970.6 CEG37786.1 - 0.016 15.1 2.0 0.019 14.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF3740 PF12548.8 CEG37786.1 - 0.045 14.2 0.2 0.08 13.4 0.1 1.4 1 1 0 1 1 1 0 Sulfatase protein DUF2417 PF10329.9 CEG37787.1 - 0.034 13.6 0.1 0.038 13.4 0.1 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF3713 PF12506.8 CEG37788.1 - 0.074 13.4 0.2 0.084 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) FAST_2 PF08368.12 CEG37789.1 - 0.068 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Thump_like PF18096.1 CEG37790.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 THUMP domain-like Peptidase_M50B PF13398.6 CEG37792.1 - 1.6e-56 191.1 17.4 1.6e-56 191.1 17.4 1.7 2 0 0 2 2 2 1 Peptidase M50B-like YfhO PF09586.10 CEG37792.1 - 0.51 8.5 7.3 0.82 7.8 7.3 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PI3_PI4_kinase PF00454.27 CEG37793.1 - 6.9e-28 98.1 0.0 9.1e-21 74.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 CEG37793.1 - 3.8e-06 27.4 0.0 9.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 CEG37793.1 - 0.09 12.9 5.0 0.27 11.4 5.0 1.8 1 0 0 1 1 1 0 FYVE zinc finger BOP1NT PF08145.12 CEG37794.1 - 4.6e-106 354.5 4.9 7.8e-106 353.7 4.9 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CEG37794.1 - 9e-33 111.8 6.5 2.2e-08 34.6 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG37794.1 - 9e-11 41.9 0.1 0.032 14.5 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CEG37794.1 - 0.049 12.0 0.0 0.087 11.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 CEG37794.1 - 0.16 12.5 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain DUF3295 PF11702.8 CEG37794.1 - 1.7 7.9 12.1 3 7.1 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.12 CEG37794.1 - 4.8 5.3 19.1 8.3 4.5 19.1 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4794 PF16042.5 CEG37795.1 - 0.093 13.7 29.4 6.7 7.8 29.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) Lin-8 PF03353.15 CEG37795.1 - 0.98 8.9 9.8 1.2 8.6 9.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HSF_DNA-bind PF00447.17 CEG37796.1 - 4.7e-21 75.2 0.7 8.5e-21 74.4 0.7 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 CEG37796.1 - 0.00085 19.7 0.1 0.0013 19.1 0.1 1.4 1 1 0 1 1 1 1 Ets-domain Bac_transf PF02397.16 CEG37797.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial sugar transferase TGT PF01702.18 CEG37798.1 - 1.7e-138 461.6 0.0 2.1e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase GCK PF07802.11 CEG37798.1 - 0.04 14.3 0.6 0.085 13.3 0.1 1.7 2 0 0 2 2 2 0 GCK domain COX6B PF02297.17 CEG37799.1 - 9.9e-17 61.0 5.5 1.2e-16 60.7 5.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CEG37799.1 - 0.024 14.7 1.5 0.035 14.1 1.5 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TPR_8 PF13181.6 CEG37799.1 - 0.056 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat CHCH PF06747.13 CEG37799.1 - 0.12 12.5 3.1 0.39 10.9 1.9 2.3 1 1 2 3 3 3 0 CHCH domain TPR_2 PF07719.17 CEG37799.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat C2 PF00168.30 CEG37800.1 - 5.9e-10 39.4 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Peptidase_C1 PF00112.23 CEG37801.1 - 3.9e-67 226.5 3.5 3.9e-67 226.5 3.5 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CEG37801.1 - 1.6e-12 47.6 0.9 3.4e-12 46.6 0.9 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CEG37801.1 - 4.1e-07 29.1 0.9 0.0021 16.9 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Corona_nucleoca PF00937.18 CEG37805.1 - 0.089 11.8 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-CCHC PF00098.23 CEG37806.1 - 3e-05 23.9 2.3 6.2e-05 22.9 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEG37806.1 - 0.31 10.8 4.0 0.64 9.8 4.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger Ndufs5 PF10200.9 CEG37808.1 - 0.0029 17.8 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa zf-RING_2 PF13639.6 CEG37809.1 - 1.7e-11 44.2 6.9 1.7e-11 44.2 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG37809.1 - 5.4e-07 29.3 7.4 5.4e-07 29.3 7.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG37809.1 - 1.2e-06 28.7 6.8 1.2e-06 28.7 6.8 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG37809.1 - 4.3e-06 26.6 4.1 4.3e-06 26.6 4.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CEG37809.1 - 2.8e-05 23.6 5.1 2.8e-05 23.6 5.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CEG37809.1 - 3.3e-05 23.5 2.7 3.3e-05 23.5 2.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEG37809.1 - 6.9e-05 22.6 5.9 6.9e-05 22.6 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG37809.1 - 9.6e-05 22.3 7.9 9.6e-05 22.3 7.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG37809.1 - 0.00051 19.8 4.2 0.00051 19.8 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG37809.1 - 0.00053 20.0 3.2 0.00077 19.5 1.5 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEG37809.1 - 0.054 13.4 1.5 0.054 13.4 1.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CEG37809.1 - 0.072 13.1 8.4 0.27 11.3 8.4 2.1 1 1 0 1 1 1 0 Zinc-finger TF_Zn_Ribbon PF08271.12 CEG37809.1 - 0.26 10.8 3.7 13 5.4 0.0 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Di19 PF05605.12 CEG37809.1 - 0.48 10.8 5.5 5.8 7.3 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 CEG37809.1 - 1.2 9.4 15.5 0.1 12.7 8.6 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Glyco_hydro_32C PF08244.12 CEG37812.1 - 5.8e-18 65.4 0.5 6.6e-18 65.2 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 CEG37812.1 - 0.018 15.1 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Peptidase_M8 PF01457.16 CEG37813.1 - 2e-49 168.7 0.3 1.8e-28 99.5 0.1 3.2 3 0 0 3 3 3 3 Leishmanolysin Glyco_hydro_32N PF00251.20 CEG37813.1 - 2.1e-44 152.3 9.4 4.8e-44 151.1 9.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CEG37813.1 - 5.3e-24 85.0 2.5 8.7e-24 84.3 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 CEG37813.1 - 0.077 13.1 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) NTP_transferase PF00483.23 CEG37814.1 - 7.6e-53 179.6 0.0 9.8e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEG37814.1 - 4.8e-11 41.9 10.3 2.4e-09 36.5 1.9 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEG37814.1 - 7e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CEG37814.1 - 0.00041 20.0 3.9 0.00041 20.0 3.9 3.0 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CEG37814.1 - 0.00093 18.2 0.2 0.24 10.3 0.2 2.8 2 1 0 2 2 2 1 L-fucokinase IspD PF01128.19 CEG37814.1 - 0.063 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase E1-E2_ATPase PF00122.20 CEG37815.1 - 1.2e-42 145.5 3.0 1.2e-42 145.5 3.0 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEG37815.1 - 1.2e-38 132.6 1.1 1.2e-38 132.6 1.1 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEG37815.1 - 5.6e-19 69.3 1.8 2.4e-15 57.4 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG37815.1 - 7.6e-18 64.0 0.0 1.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEG37815.1 - 2.3e-17 62.8 0.1 1.3e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEG37815.1 - 0.021 14.6 0.7 0.021 14.6 0.7 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Arm PF00514.23 CEG37816.1 - 1.5e-26 91.5 15.7 2.1e-09 37.1 0.1 7.7 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CEG37816.1 - 1.8e-09 37.0 0.0 4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 CEG37816.1 - 9e-07 29.3 0.9 2.7e-06 27.7 0.4 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 CEG37816.1 - 4.7e-06 26.9 2.3 0.18 12.2 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CEG37816.1 - 1.4e-05 25.5 5.7 0.18 12.3 0.9 4.8 3 2 2 5 5 5 3 HEAT-like repeat HEAT PF02985.22 CEG37816.1 - 0.0051 17.0 6.1 4.9 7.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Arm_2 PF04826.13 CEG37816.1 - 0.054 13.0 0.1 2.3 7.6 0.1 2.9 3 0 0 3 3 3 0 Armadillo-like Cnd1 PF12717.7 CEG37816.1 - 0.072 13.1 0.2 4.4 7.3 0.1 2.8 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AKAP28 PF14469.6 CEG37816.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 28 kDa A-kinase anchor DUF1841 PF08897.11 CEG37818.1 - 0.22 11.6 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Complex1_LYR PF05347.15 CEG37819.1 - 3.2e-10 39.9 0.2 4.2e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CEG37819.1 - 0.00026 21.5 0.0 0.00032 21.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 CEG37819.1 - 0.061 14.1 0.9 0.076 13.8 0.9 1.2 1 0 0 1 1 1 0 Complex1_LYR-like IFT46_B_C PF12317.8 CEG37820.1 - 3.7e-93 311.1 0.2 7.4e-93 310.1 0.2 1.5 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal OTU PF02338.19 CEG37821.1 - 3.5e-14 53.4 0.0 1.5e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEG37821.1 - 5.4e-06 26.0 0.4 0.0062 16.0 0.0 2.5 1 1 1 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 CEG37822.1 - 5.3e-15 56.0 0.6 2.4e-14 53.9 0.2 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEG37822.1 - 0.0028 17.2 0.6 2.5 7.5 0.3 2.6 2 1 0 2 2 2 2 Peptidase C65 Otubain DUF1704 PF08014.11 CEG37822.1 - 0.051 12.6 0.6 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1704) Fcf2 PF08698.11 CEG37823.1 - 3.5e-33 113.9 0.7 3.5e-33 113.9 0.7 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Abhydrolase_3 PF07859.13 CEG37824.1 - 4.7e-11 43.0 1.8 0.00066 19.6 0.0 3.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEG37824.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase EamA PF00892.20 CEG37826.1 - 6.1e-29 100.9 24.2 1.3e-16 61.0 14.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CEG37826.1 - 0.00036 20.0 14.8 0.011 15.1 4.2 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CEG37827.1 - 1.5e-30 106.1 34.1 6.8e-19 68.4 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CEG37827.1 - 0.61 9.4 20.7 6.9 5.9 20.5 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family Ank_2 PF12796.7 CEG37828.1 - 5.2e-26 91.1 1.3 2e-14 53.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG37828.1 - 6.2e-22 77.4 1.3 1.8e-07 31.3 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG37828.1 - 7.3e-22 77.5 0.0 2.6e-08 34.2 0.0 4.8 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG37828.1 - 3.3e-20 71.6 3.1 1.8e-05 24.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CEG37828.1 - 5.1e-17 60.2 0.2 0.00065 20.0 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 CEG37828.1 - 2.9e-16 59.4 11.0 4.5e-16 58.7 11.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG37828.1 - 0.013 15.7 7.5 0.013 15.7 7.5 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger ER_lumen_recept PF00810.18 CEG37829.1 - 1.3e-34 120.1 5.5 1.3e-34 120.1 5.5 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor Y_phosphatase PF00102.27 CEG37832.1 - 1e-09 38.3 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG37832.1 - 8.8e-09 35.3 0.0 2.8e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CEG37832.1 - 0.00034 20.3 0.1 0.00065 19.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 CEG37832.1 - 0.0028 17.3 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE PF01363.21 CEG37832.1 - 0.011 15.9 0.5 0.042 14.0 0.5 2.0 1 0 0 1 1 1 0 FYVE zinc finger Y_phosphatase3 PF13350.6 CEG37832.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GAS PF13851.6 CEG37833.1 - 0.0041 16.5 17.9 0.0041 16.5 17.9 9.3 3 3 5 8 8 8 2 Growth-arrest specific micro-tubule binding ToxB_N PF18224.1 CEG37833.1 - 0.023 14.6 0.1 0.072 13.0 0.1 1.8 1 0 0 1 1 1 0 ToxB N-terminal domain CheY-binding PF09078.11 CEG37833.1 - 1.7 8.8 11.4 0.081 13.1 0.4 4.3 4 0 0 4 4 4 0 CheY binding Ank_2 PF12796.7 CEG37839.1 - 4.5e-37 126.5 1.4 4.3e-12 46.4 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG37839.1 - 3.2e-31 107.3 0.1 1.2e-08 35.3 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG37839.1 - 1.2e-29 99.0 0.1 0.00077 19.7 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 CEG37839.1 - 5.3e-28 96.2 0.4 0.00025 21.3 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CEG37839.1 - 8e-25 86.6 0.8 3.7e-05 23.9 0.1 5.0 2 2 1 4 4 4 4 Ankyrin repeats (many copies) TPR_1 PF00515.28 CEG37839.1 - 7.9e-06 25.5 8.3 0.038 13.8 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG37839.1 - 2.9e-05 23.6 1.8 0.00024 20.7 1.7 2.4 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 CEG37839.1 - 7e-05 23.4 6.4 0.037 14.7 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37839.1 - 0.00015 21.6 16.0 0.02 14.9 0.2 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG37839.1 - 0.0055 16.8 1.7 0.0055 16.8 1.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Glyoxalase_6 PF18029.1 CEG37839.1 - 0.0063 17.3 0.5 0.27 12.0 0.1 2.9 2 1 0 2 2 2 1 Glyoxalase-like domain ANAPC3 PF12895.7 CEG37839.1 - 0.024 14.9 3.7 0.044 14.0 2.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3231 PF11553.8 CEG37839.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) PEGA PF08308.11 CEG37839.1 - 0.051 13.5 0.2 8.3 6.4 0.0 3.1 3 0 0 3 3 3 0 PEGA domain COesterase PF00135.28 CEG37839.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family YlbD_coat PF14071.6 CEG37839.1 - 2.5 8.4 8.9 0.067 13.4 1.1 2.2 2 0 0 2 2 2 0 Putative coat protein TPR_8 PF13181.6 CEG37839.1 - 2.9 8.3 5.6 1.8 9.0 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37839.1 - 7.3 7.2 9.1 20 5.8 3.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37839.1 - 9.1 7.4 7.7 6.3 7.9 0.3 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 CEG37840.1 - 1.6e-33 115.8 0.0 1.9e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Rsm1 PF08600.10 CEG37844.1 - 0.024 14.8 0.3 0.044 13.9 0.3 1.4 1 0 0 1 1 1 0 Rsm1-like Retrotran_gag_2 PF14223.6 CEG37846.1 - 3.2e-18 65.7 0.4 3.8e-18 65.5 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tetraspanin PF00335.20 CEG37849.1 - 4e-08 33.3 11.5 9e-08 32.1 11.5 1.5 1 1 0 1 1 1 1 Tetraspanin family ABC2_membrane_2 PF12679.7 CEG37849.1 - 1.6 8.0 5.9 2.4 7.4 3.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2733 PF10813.8 CEG37849.1 - 2.8 7.8 5.4 0.38 10.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DUF5480 PF17576.2 CEG37849.1 - 2.9 7.9 6.0 0.39 10.7 0.2 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5480) Tetraspanin PF00335.20 CEG37850.1 - 7.5e-14 52.0 10.5 1.4e-13 51.1 10.5 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2157 PF09925.9 CEG37850.1 - 4.8e-05 23.2 0.9 0.0037 17.1 0.0 3.1 2 1 0 3 3 3 1 Predicted membrane protein (DUF2157) UPF0239 PF06783.11 CEG37850.1 - 0.21 11.8 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Phage_holin_3_6 PF07332.11 CEG37850.1 - 0.37 10.9 16.8 0.21 11.7 8.2 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III EphA2_TM PF14575.6 CEG37850.1 - 1.6 9.7 8.7 3.1 8.8 0.0 3.4 2 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain zf-RING_2 PF13639.6 CEG37852.1 - 2.8e-09 37.1 15.4 4.8e-09 36.4 15.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG37852.1 - 4.4e-06 26.4 16.3 7.4e-06 25.7 16.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG37852.1 - 2.4e-05 24.5 15.7 0.00011 22.4 15.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG37852.1 - 0.00064 19.5 15.9 0.0012 18.7 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG37852.1 - 0.0046 16.8 13.2 0.0074 16.1 13.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CEG37852.1 - 0.005 17.0 7.8 0.0085 16.2 7.8 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CEG37852.1 - 0.013 15.6 5.7 0.026 14.6 5.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PAD_N PF08526.10 CEG37852.1 - 0.05 14.0 2.8 7.1 7.0 0.1 2.5 3 0 0 3 3 3 0 Protein-arginine deiminase (PAD) N-terminal domain zf-RING_5 PF14634.6 CEG37852.1 - 0.13 12.3 13.7 0.22 11.5 13.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CEG37852.1 - 0.52 10.0 10.6 1 9.0 10.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CEG37852.1 - 3.5 7.9 9.8 18 5.6 9.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 CEG37852.1 - 9.9 6.0 19.6 0.055 13.2 10.5 2.0 2 0 0 2 2 2 0 RING-like zinc finger Neurochondrin PF05536.11 CEG37853.1 - 6.1e-34 117.4 12.8 1.3e-20 73.3 6.7 2.1 2 0 0 2 2 2 2 Neurochondrin GTP_cyclohydro2 PF00925.20 CEG37854.1 - 9e-54 181.5 0.0 1.3e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4903 PF16246.5 CEG37854.1 - 0.18 11.4 0.0 0.63 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4903) Got1 PF04178.12 CEG37856.1 - 6.4e-16 58.8 12.9 8.2e-16 58.4 12.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1624 PF07786.12 CEG37856.1 - 0.24 10.9 7.9 0.3 10.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF308 PF03729.13 CEG37856.1 - 0.33 11.3 18.2 0.11 12.8 10.5 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF2157 PF09925.9 CEG37856.1 - 0.34 10.7 8.5 0.46 10.3 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF373 PF04123.13 CEG37856.1 - 1.3 8.4 6.0 2 7.8 5.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Anoctamin PF04547.12 CEG37856.1 - 3.5 6.3 5.2 0.72 8.6 1.9 1.5 1 1 1 2 2 2 0 Calcium-activated chloride channel FlaC_arch PF05377.11 CEG37857.1 - 5.5 7.5 9.6 36 4.8 0.1 4.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HisG PF01634.18 CEG37858.1 - 1.4e-53 181.2 0.1 1.9e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CEG37858.1 - 1.7e-23 82.6 0.1 2.8e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 CEG37858.1 - 1.7e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Glyco_hydro_115 PF15979.5 CEG37858.1 - 0.15 11.5 0.3 4.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 115 Imm30 PF15565.6 CEG37859.1 - 0.017 15.2 0.5 0.029 14.4 0.5 1.4 1 0 0 1 1 1 0 Immunity protein 30 PAH PF02671.21 CEG37860.1 - 0.0063 16.6 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat GldM_N PF12081.8 CEG37860.1 - 0.03 14.4 0.3 0.053 13.6 0.2 1.4 1 1 0 1 1 1 0 GldM N-terminal domain Sec34 PF04136.15 CEG37860.1 - 0.052 13.4 2.9 0.041 13.8 1.2 1.7 2 0 0 2 2 2 0 Sec34-like family UPF0449 PF15136.6 CEG37860.1 - 0.059 13.8 0.8 0.12 12.8 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 FapA PF03961.13 CEG37860.1 - 0.071 11.7 0.5 0.084 11.5 0.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 CEG37860.1 - 0.15 11.9 2.9 0.98 9.3 0.2 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FGAR-AT_linker PF18072.1 CEG37860.1 - 0.93 10.1 3.3 2.2 8.9 0.4 2.7 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain TPR_12 PF13424.6 CEG37861.1 - 2.6e-24 85.3 6.0 1.1e-11 44.8 0.0 4.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG37861.1 - 6.8e-16 57.6 0.5 2.8e-06 27.0 0.0 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37861.1 - 8.8e-12 44.8 2.2 0.15 13.0 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37861.1 - 2.6e-11 42.7 4.7 0.12 12.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG37861.1 - 9.6e-07 29.4 0.7 9 7.0 0.0 4.7 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG37861.1 - 1.2e-06 29.0 9.1 0.16 12.5 0.2 4.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG37861.1 - 6.3e-06 26.0 9.1 0.016 15.4 0.0 5.9 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG37861.1 - 8.2e-06 25.4 0.8 1.5e-05 24.6 0.8 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 CEG37861.1 - 1.1e-05 25.1 0.8 21 5.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37861.1 - 0.00024 20.8 3.5 1.7 8.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG37861.1 - 0.00031 20.4 0.2 6.6 6.5 0.1 4.4 5 0 0 5 5 4 1 TPR repeat ANAPC3 PF12895.7 CEG37861.1 - 0.00033 20.8 2.2 5.4 7.3 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF4094 PF13334.6 CEG37861.1 - 0.0035 17.7 0.2 1.3 9.5 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4094) TPR_6 PF13174.6 CEG37861.1 - 0.0066 17.0 5.5 18 6.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 CEG37861.1 - 0.0076 16.7 1.0 0.05 14.0 0.1 2.5 2 2 0 2 2 2 1 Bacterial transcriptional activator domain Lambda_Kil PF06301.11 CEG37861.1 - 0.058 13.0 0.6 0.43 10.2 0.0 2.6 3 0 0 3 3 2 0 Bacteriophage lambda Kil protein HTH_50 PF18024.1 CEG37861.1 - 0.076 12.6 2.4 0.12 12.1 0.3 2.4 2 1 2 4 4 4 0 Helix-turn-helix domain DUF3856 PF12968.7 CEG37861.1 - 0.096 12.8 2.5 1.5 8.9 0.2 3.5 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 CEG37861.1 - 0.098 12.7 0.2 20 5.3 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 CEG37861.1 - 0.14 12.4 0.0 46 4.6 0.0 3.7 4 0 0 4 4 3 0 PPR repeat PPR_2 PF13041.6 CEG37861.1 - 0.17 12.1 0.4 40 4.5 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family TPR_21 PF09976.9 CEG37861.1 - 0.17 11.6 6.9 0.91 9.2 2.0 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain YL1 PF05764.13 CEG37862.1 - 1.5e-26 94.0 23.9 1.5e-26 94.0 23.9 2.7 2 1 0 2 2 2 1 YL1 nuclear protein PQ-loop PF04193.14 CEG37863.1 - 7.9e-27 92.8 3.2 4.1e-13 48.9 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat IgaA PF07095.11 CEG37863.1 - 0.037 12.0 0.6 0.052 11.5 0.6 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA SAICAR_synt PF01259.18 CEG37864.1 - 9.9e-80 267.8 0.0 1.3e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HTH_3 PF01381.22 CEG37864.1 - 0.099 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix Mg_trans_NIPA PF05653.14 CEG37865.1 - 4.9e-37 127.6 14.2 3.5e-36 124.8 14.2 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEG37865.1 - 7.1e-07 29.5 2.3 7.1e-07 29.5 2.3 2.6 3 0 0 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 CEG37865.1 - 9.8e-06 25.6 1.9 1.8e-05 24.7 0.0 2.3 3 0 0 3 3 3 1 Putative transmembrane family 234 CRT-like PF08627.10 CEG37865.1 - 0.00021 20.3 0.4 0.00047 19.2 0.4 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RWP-RK PF02042.15 CEG37866.1 - 1.3e-21 76.3 0.3 2.4e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 RWP-RK domain Peptidase_C48 PF02902.19 CEG37868.1 - 5.4e-10 39.5 0.1 6.6e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TehB PF03848.14 CEG37868.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Tellurite resistance protein TehB IL31 PF15209.6 CEG37868.1 - 0.078 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin 31 zf-RanBP PF00641.18 CEG37870.1 - 0.00087 18.6 12.6 0.0016 17.7 12.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Rossmann-like PF10727.9 CEG37870.1 - 0.0051 16.7 0.3 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 Rossmann-like domain DUF2321 PF10083.9 CEG37870.1 - 0.11 12.2 0.3 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) NINJA_B PF16136.5 CEG37871.1 - 3.8 7.9 13.2 0.13 12.6 4.0 2.8 2 1 0 2 2 2 0 Putative nuclear localisation signal LRR_4 PF12799.7 CEG37872.1 - 1.6e-05 25.2 0.5 0.37 11.3 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG37872.1 - 3.5e-05 23.5 1.4 0.00011 21.8 0.2 2.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 CEG37872.1 - 0.017 15.6 2.1 1.2 10.0 0.2 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat DUF755 PF05501.11 CEG37872.1 - 0.02 15.2 2.6 0.047 14.0 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MTBP_N PF14918.6 CEG37872.1 - 0.062 12.8 0.7 2.4 7.6 0.3 2.2 2 0 0 2 2 2 0 MDM2-binding DUF2383 PF09537.10 CEG37872.1 - 0.15 12.4 1.0 1 9.7 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Syntaxin-6_N PF09177.11 CEG37872.1 - 0.21 12.1 3.2 0.31 11.6 0.6 2.5 2 2 0 2 2 2 0 Syntaxin 6, N-terminal PilO PF04350.13 CEG37872.1 - 1.1 9.4 7.5 0.23 11.6 0.8 2.7 3 0 0 3 3 3 0 Pilus assembly protein, PilO SpecificRecomb PF10136.9 CEG37872.1 - 1.4 7.1 7.7 0.59 8.4 1.1 2.3 1 1 1 2 2 2 0 Site-specific recombinase FPL PF09758.9 CEG37873.1 - 1.5e-41 141.9 0.1 5e-41 140.2 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein TPR_MLP1_2 PF07926.12 CEG37874.1 - 2.8e-15 56.5 21.7 2.8e-15 56.5 21.7 14.7 6 3 8 14 14 14 5 TPR/MLP1/MLP2-like protein BCL_N PF04714.13 CEG37874.1 - 2.5 8.2 5.5 1.6 8.9 0.1 3.3 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Pkinase_Tyr PF07714.17 CEG37876.1 - 6.8e-37 127.2 0.1 9.8e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG37876.1 - 1.4e-30 106.6 0.0 2.1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 CEG37876.1 - 8.4e-16 57.5 33.5 1.6e-07 30.9 6.5 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEG37876.1 - 1.3e-08 35.0 11.1 8.7e-06 26.0 4.0 3.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG37876.1 - 0.011 15.7 8.7 0.62 10.3 0.2 3.9 3 0 0 3 3 3 0 Leucine Rich repeat RIO1 PF01163.22 CEG37876.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CEG37876.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CEG37876.1 - 0.035 13.4 0.0 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM190 PF15431.6 CEG37876.1 - 0.048 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Transmembrane protein 190 DUF3827 PF12877.7 CEG37876.1 - 0.073 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) LRR_1 PF00560.33 CEG37876.1 - 0.14 12.8 3.2 1.8e+02 3.3 0.1 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat CxC6 PF18721.1 CEG37877.1 - 0.06 13.6 20.5 1.7 9.0 4.5 3.3 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Pkinase_Tyr PF07714.17 CEG37878.1 - 1.4e-20 73.7 0.1 1.9e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG37878.1 - 5.1e-16 58.8 0.0 3.5e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 CEG37878.1 - 6.7e-06 25.8 0.7 3.2e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CEG37878.1 - 0.11 13.0 2.2 0.56 10.7 0.4 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Arf PF00025.21 CEG37879.1 - 7.9e-34 116.6 0.0 1.4e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEG37879.1 - 1.8e-09 37.3 0.0 3.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CEG37879.1 - 2.3e-08 34.3 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEG37879.1 - 2.7e-08 33.4 0.0 7.9e-06 25.3 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CEG37879.1 - 3.7e-07 29.9 0.0 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEG37879.1 - 2.8e-05 24.2 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Tudor_3 PF18115.1 CEG37879.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain GTP_EFTU PF00009.27 CEG37879.1 - 0.0009 18.8 0.8 0.017 14.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 CEG37879.1 - 0.0028 17.6 0.0 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CEG37879.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CEG37879.1 - 0.013 16.0 0.2 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 CEG37879.1 - 0.014 15.0 0.4 0.7 9.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CEG37879.1 - 0.016 15.1 0.3 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 CEG37879.1 - 0.017 15.4 0.4 0.059 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CEG37879.1 - 0.025 14.2 0.3 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CEG37879.1 - 0.031 14.2 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 CEG37879.1 - 0.031 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 CEG37879.1 - 0.035 13.9 0.3 8.8 6.0 0.1 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein TUDOR_5 PF18359.1 CEG37879.1 - 0.04 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 NOG1 PF06858.14 CEG37879.1 - 0.083 12.7 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Thymidylate_kin PF02223.17 CEG37879.1 - 0.094 12.4 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 CEG37879.1 - 0.11 12.2 0.2 0.32 10.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEG37879.1 - 0.41 10.9 2.4 0.59 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2262 PF10020.9 CEG37879.1 - 2.5 8.5 4.5 2.1 8.8 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2262) DnaJ PF00226.31 CEG37880.1 - 2.8e-21 75.4 0.2 1.6e-20 72.9 0.2 2.5 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CEG37880.1 - 9.5e-09 35.3 1.8 2.6e-08 33.9 1.8 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG37880.1 - 5.4e-07 29.8 2.4 1.3e-06 28.6 2.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEG37880.1 - 0.00052 20.6 0.4 0.0016 19.1 0.4 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CEG37880.1 - 0.00063 20.0 0.4 0.00063 20.0 0.4 2.4 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CEG37880.1 - 0.006 17.0 1.0 0.021 15.3 1.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-BED PF02892.15 CEG37880.1 - 0.023 14.7 1.6 0.064 13.3 1.6 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 CEG37880.1 - 0.027 14.5 6.5 0.028 14.4 2.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.12 CEG37880.1 - 0.11 12.6 1.0 0.44 10.7 1.0 2.0 1 0 0 1 1 1 0 DBF zinc finger HD PF01966.22 CEG37880.1 - 5.3 7.3 7.0 1.1 9.4 2.8 2.1 2 0 0 2 2 2 0 HD domain Mre11_DNA_bind PF04152.14 CEG37885.1 - 7.8e-38 130.4 0.2 7.8e-38 130.4 0.2 2.6 4 0 0 4 4 4 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CEG37885.1 - 1.5e-14 55.0 0.1 2.7e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG37885.1 - 6.8e-05 23.1 0.0 0.0047 17.1 0.0 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PWI PF01480.17 CEG37886.1 - 0.00026 21.2 0.2 0.00051 20.3 0.2 1.4 1 0 0 1 1 1 1 PWI domain SPOB_ab PF14682.6 CEG37886.1 - 0.15 12.2 0.5 0.9 9.6 0.1 2.0 1 1 1 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal DUF4265 PF14085.6 CEG37886.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) TMEM154 PF15102.6 CEG37889.1 - 0.00066 19.6 0.7 0.0017 18.3 0.7 1.7 1 0 0 1 1 1 1 TMEM154 protein family HemY_N PF07219.13 CEG37889.1 - 0.0026 18.0 0.4 0.005 17.0 0.4 1.4 1 0 0 1 1 1 1 HemY protein N-terminus Amnionless PF14828.6 CEG37889.1 - 0.004 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.11 CEG37889.1 - 0.013 15.6 1.4 0.035 14.2 1.4 1.7 1 0 0 1 1 1 0 Podoplanin DUF4834 PF16118.5 CEG37889.1 - 0.19 12.7 0.1 0.19 12.7 0.1 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) Phage_holin_2_4 PF16082.5 CEG37889.1 - 0.19 11.5 0.0 0.55 10.0 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like RIFIN PF02009.16 CEG37889.1 - 0.24 11.2 0.2 0.44 10.4 0.2 1.3 1 0 0 1 1 1 0 Rifin DUF1298 PF06974.13 CEG37894.1 - 3.9e-30 104.7 0.2 9.2e-30 103.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 CEG37894.1 - 6.4e-13 49.1 0.2 4.9e-11 42.9 0.0 2.9 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain GTP_EFTU PF00009.27 CEG37895.1 - 7.2e-27 94.2 0.0 1.1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEG37895.1 - 3.5e-08 33.7 0.8 9.1e-08 32.4 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEG37895.1 - 4.9e-08 33.3 0.2 3.3e-06 27.4 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG37895.1 - 2.1e-05 24.5 0.0 5.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG37895.1 - 0.00057 19.8 1.7 0.16 11.8 0.5 2.6 2 1 0 2 2 2 2 RsgA GTPase Roc PF08477.13 CEG37895.1 - 0.0018 18.5 0.0 0.58 10.4 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CEG37895.1 - 0.0032 17.3 0.1 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CEG37895.1 - 0.043 13.4 2.0 5 6.6 0.3 2.9 3 1 0 3 3 3 0 Ferrous iron transport protein B LTV PF04180.14 CEG37896.1 - 1.9e-09 37.7 38.9 0.00051 19.9 16.2 4.0 2 1 1 3 3 3 3 Low temperature viability protein MULE PF10551.9 CEG37897.1 - 0.00023 21.5 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Cmc1 PF08583.10 CEG37897.1 - 0.074 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like MFS_1 PF07690.16 CEG37898.1 - 4.5e-16 58.7 4.2 6.6e-16 58.2 4.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily WW PF00397.26 CEG37898.1 - 2.5e-07 30.7 0.2 1.6e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 WW domain PDZ PF00595.24 CEG37898.1 - 0.0008 19.7 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CEG37898.1 - 0.0095 16.2 0.0 0.031 14.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Spc7 PF08317.11 CEG37898.1 - 0.11 11.3 10.3 0.095 11.6 4.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 CEG37898.1 - 0.16 10.5 3.4 0.27 9.8 3.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Wtap PF17098.5 CEG37898.1 - 0.35 10.8 7.3 0.77 9.7 7.3 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Seryl_tRNA_N PF02403.22 CEG37898.1 - 5.4 7.3 8.4 3.9 7.7 2.1 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain THOC7 PF05615.13 CEG37898.1 - 8.9 6.6 9.7 13 6.1 6.8 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 Fib_alpha PF08702.10 CEG37898.1 - 9.5 6.4 6.8 34 4.6 1.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_M24 PF00557.24 CEG37899.1 - 8.2e-05 22.4 0.2 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CEG37899.1 - 0.0047 17.6 0.1 0.0097 16.6 0.1 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain EutC PF05985.11 CEG37899.1 - 0.051 12.9 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Creatinase_N_2 PF16189.5 CEG37899.1 - 0.17 12.0 0.1 1.1 9.3 0.0 2.2 2 1 0 2 2 2 0 Creatinase/Prolidase N-terminal domain 2-Hacid_dh_C PF02826.19 CEG37900.1 - 7.4e-51 172.0 0.0 1.1e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEG37900.1 - 2.2e-28 98.6 0.0 3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 CEG37900.1 - 8.5e-06 25.5 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 CEG37900.1 - 0.00017 21.8 0.2 0.00077 19.7 0.2 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CEG37900.1 - 0.00026 21.1 0.3 0.0005 20.2 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 CEG37900.1 - 0.049 12.9 1.5 1 8.6 1.5 2.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACT_4 PF13291.6 CEG37900.1 - 0.11 13.1 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain Ribosomal_L37ae PF01780.19 CEG37901.1 - 5.8e-41 138.5 7.9 6.5e-41 138.3 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 CEG37901.1 - 0.018 15.0 3.2 0.032 14.2 3.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Vps39_2 PF10367.9 CEG37901.1 - 0.026 15.0 0.1 0.031 14.7 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF1451 PF07295.11 CEG37901.1 - 0.098 12.7 0.8 0.14 12.2 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-BED PF02892.15 CEG37901.1 - 0.44 10.6 9.3 0.46 10.5 0.5 2.7 2 1 1 3 3 3 0 BED zinc finger FKS1_dom1 PF14288.6 CEG37904.1 - 7e-24 84.6 2.0 1.2e-21 77.4 2.0 2.7 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aldedh PF00171.22 CEG37905.1 - 5.4e-172 572.4 0.2 6.1e-172 572.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 CEG37906.1 - 1.7e-20 72.6 0.1 2.4e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CEG37906.1 - 4.4e-10 39.5 4.9 8.7e-10 38.5 4.9 1.5 1 0 0 1 1 1 1 WW domain RRM_5 PF13893.6 CEG37906.1 - 2.2e-05 24.0 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 CEG37906.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 RVT_1 PF00078.27 CEG37910.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEG37910.1 - 0.18 12.0 0.5 0.47 10.6 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEG37910.1 - 4.4 7.4 5.8 1.2 9.1 1.8 2.0 2 0 0 2 2 2 0 Zinc knuckle Bac_luciferase PF00296.20 CEG37911.1 - 0.016 14.7 2.1 0.02 14.4 2.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Elongin_A PF06881.11 CEG37911.1 - 0.066 13.7 1.2 0.17 12.4 1.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3235 PF11574.8 CEG37911.1 - 2.3 9.1 11.3 8.3 7.4 11.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Glyco_hydro_9 PF00759.19 CEG37911.1 - 4 6.8 13.0 9.4 5.5 13.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 AIRC PF00731.20 CEG37913.1 - 2.9e-16 59.4 1.9 2.9e-16 59.4 1.9 2.4 3 0 0 3 3 3 1 AIR carboxylase Peptidase_C37 PF05416.12 CEG37913.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glycos_trans_3N PF02885.17 CEG37913.1 - 0.14 12.0 0.4 0.94 9.4 0.4 2.3 1 1 0 1 1 1 0 Glycosyl transferase family, helical bundle domain SR-25 PF10500.9 CEG37914.1 - 0.0022 17.7 0.5 0.0026 17.4 0.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Circo_capsid PF02443.15 CEG37914.1 - 0.017 14.7 4.4 0.019 14.6 4.4 1.0 1 0 0 1 1 1 0 Circovirus capsid protein Nmad3 PF18754.1 CEG37914.1 - 0.055 13.0 0.8 0.063 12.8 0.8 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Metallophos PF00149.28 CEG37915.1 - 4.7e-05 24.0 1.9 4.7e-05 24.0 1.9 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 CEG37916.1 - 2.1e-22 79.5 3.2 8.5e-09 35.9 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG37916.1 - 6.1e-19 68.1 2.2 1.7e-05 25.3 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG37916.1 - 4.1e-16 57.5 4.1 0.019 15.4 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CEG37916.1 - 2.3e-12 46.8 7.2 0.021 15.3 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CEG37916.1 - 1.5e-10 41.1 5.2 0.002 18.4 0.1 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Pkinase PF00069.25 CEG37917.1 - 3.8e-55 187.1 0.0 9.1e-55 185.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37917.1 - 1e-40 139.7 0.0 1.8e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 CEG37917.1 - 1.9e-38 132.4 0.6 2.7e-38 131.9 0.6 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 CEG37917.1 - 0.001 18.5 1.4 0.002 17.5 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 CEG37917.1 - 0.18 11.7 0.9 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fib_alpha PF08702.10 CEG37917.1 - 5.2 7.2 7.3 42 4.3 0.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PHD PF00628.29 CEG37918.1 - 6.7e-08 32.3 4.1 6.7e-08 32.3 4.1 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CEG37918.1 - 0.071 13.1 3.4 0.23 11.4 3.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ZF-HD_dimer PF04770.12 CEG37918.1 - 0.31 11.4 5.3 0.28 11.5 2.1 2.5 2 0 0 2 2 2 0 ZF-HD protein dimerisation region C1_1 PF00130.22 CEG37918.1 - 1.1 9.2 4.6 0.7 9.8 0.8 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ThiF PF00899.21 CEG37919.1 - 1.1e-60 205.1 1.9 4.1e-60 203.2 0.3 2.3 3 0 0 3 3 3 1 ThiF family Rhodanese PF00581.20 CEG37919.1 - 1.9e-05 25.2 0.0 5.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 CEG37919.1 - 0.018 15.3 1.6 0.25 11.6 1.6 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEG37919.1 - 0.023 14.8 0.2 0.11 12.6 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 CEG37919.1 - 0.033 14.8 0.1 0.074 13.7 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 CEG37919.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CEG37919.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CEG37919.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRM_1 PF00076.22 CEG37923.1 - 1.1e-13 50.8 0.1 1.6e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_4 PF13837.6 CEG37924.1 - 4.5e-05 23.7 0.7 9.5e-05 22.7 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CEG37924.1 - 0.0014 19.6 1.3 0.0035 18.3 1.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CEG37924.1 - 0.0034 17.4 1.5 0.0049 16.9 0.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CEG37924.1 - 0.038 14.3 1.5 0.11 12.8 1.5 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DBD_Tnp_Mut PF03108.15 CEG37924.1 - 0.039 13.9 0.2 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 MuDR family transposase DUF1759 PF03564.15 CEG37924.1 - 0.18 11.7 2.7 1 9.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) AMP-binding PF00501.28 CEG37925.1 - 4e-93 312.3 0.0 4.7e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEG37925.1 - 2.1e-15 57.5 0.2 6.6e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain FYVE PF01363.21 CEG37926.1 - 6.4e-15 55.1 11.5 6.4e-15 55.1 11.5 2.4 2 0 0 2 2 2 1 FYVE zinc finger ILVD_EDD PF00920.21 CEG37927.1 - 1.3e-198 660.8 0.7 2.2e-149 498.4 0.1 2.0 1 1 1 2 2 2 2 Dehydratase family FeoA PF04023.14 CEG37927.1 - 0.019 15.2 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 FeoA domain Sulfotransfer_4 PF17784.1 CEG37928.1 - 0.0047 16.8 0.1 0.0063 16.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Myotub-related PF06602.14 CEG37931.1 - 1.1e-112 376.5 0.0 1.4e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CEG37931.1 - 0.0045 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEG37931.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.8 CEG37931.1 - 0.048 13.4 0.7 0.16 11.7 0.7 1.9 1 0 0 1 1 1 0 Myotubularin-associated protein FoP_duplication PF13865.6 CEG37933.1 - 5 7.7 10.4 11 6.6 10.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SNF2_N PF00176.23 CEG37936.1 - 1.3e-62 211.5 0.7 2.6e-62 210.6 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CEG37936.1 - 1.5e-16 60.0 0.1 3.5e-07 30.0 0.0 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CEG37936.1 - 2.1e-16 60.3 0.0 6.1e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG37936.1 - 3.2e-08 33.8 0.0 8.4e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG37936.1 - 3.9e-06 26.7 0.0 1.7e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD PF00628.29 CEG37936.1 - 6.8e-06 25.9 4.8 6.8e-06 25.9 4.8 3.9 4 0 0 4 4 4 1 PHD-finger HDA2-3 PF11496.8 CEG37936.1 - 0.00037 19.8 2.3 0.00085 18.6 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 CEG37936.1 - 0.0074 16.6 0.3 0.16 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain CHDCT2 PF08074.11 CEG37936.1 - 0.1 12.8 0.0 0.1 12.8 0.0 3.4 5 0 0 5 5 5 0 CHDCT2 (NUC038) domain DZR PF12773.7 CEG37936.1 - 4.4 7.4 6.9 6.3 6.9 5.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon NHL PF01436.21 CEG37937.1 - 6.7e-27 92.1 15.0 2.4e-07 30.4 0.3 8.2 8 1 0 8 8 8 6 NHL repeat LCCL PF03815.19 CEG37937.1 - 1.9e-14 53.5 0.8 1.9e-13 50.3 0.2 3.1 3 0 0 3 3 3 1 LCCL domain EGF_2 PF07974.13 CEG37937.1 - 2.4e-07 31.0 211.3 0.053 13.9 3.5 15.1 13 2 1 14 14 14 10 EGF-like domain SGL PF08450.12 CEG37937.1 - 5e-06 26.3 0.4 0.8 9.2 0.1 4.4 4 0 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 CEG37937.1 - 0.006 16.6 1.6 1.6 8.8 0.1 3.2 2 0 0 2 2 2 2 Beta-propeller repeat Rxt3 PF08642.10 CEG37937.1 - 0.012 16.4 0.0 0.031 15.1 0.0 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Phage_holin_2_4 PF16082.5 CEG37937.1 - 0.04 13.7 0.7 0.093 12.5 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like EMG1 PF03587.14 CEG37938.1 - 5.7e-75 251.2 0.0 6.6e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Nudc_N PF14050.6 CEG37939.1 - 7.3e-22 77.1 0.1 1.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 CEG37939.1 - 7.5e-16 58.9 1.0 1.3e-15 58.2 1.0 1.4 1 0 0 1 1 1 1 CS domain SecA_SW PF07516.13 CEG37939.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Peroxin-3 PF04882.12 CEG37940.1 - 4.3e-12 45.8 13.7 2.7e-08 33.3 4.9 3.6 1 1 1 2 2 2 2 Peroxin-3 TMP_2 PF06791.13 CEG37940.1 - 0.015 15.0 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein RloB PF13707.6 CEG37940.1 - 0.088 13.0 2.5 0.14 12.4 2.5 1.3 1 0 0 1 1 1 0 RloB-like protein MotA_ExbB PF01618.16 CEG37940.1 - 0.78 9.5 2.9 0.93 9.3 0.1 2.5 2 2 0 2 2 2 0 MotA/TolQ/ExbB proton channel family G6PD_C PF02781.16 CEG37941.1 - 5.4e-107 357.3 0.0 1.3e-106 356.1 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEG37941.1 - 6.1e-56 189.8 0.0 2.2e-55 188.0 0.0 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DOT1 PF08123.13 CEG37941.1 - 1.4e-22 80.2 0.0 2.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CEG37941.1 - 1.4e-05 24.7 0.1 6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 CEG37941.1 - 0.0033 18.1 0.0 0.0074 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG37941.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CEG37941.1 - 0.022 14.4 0.1 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 CEG37941.1 - 0.061 14.1 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CEG37941.1 - 0.14 12.8 0.0 0.4 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Telomere_Sde2_2 PF13297.6 CEG37942.1 - 3.1e-24 84.4 0.4 5.4e-24 83.6 0.4 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal SPRY PF00622.28 CEG37942.1 - 2.2e-23 82.6 0.0 3.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Sde2_N_Ubi PF13019.6 CEG37942.1 - 1.1e-19 70.9 0.2 2.6e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain zf-CCCH PF00642.24 CEG37942.1 - 0.027 14.4 1.5 0.15 12.0 1.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_27 PF13514.6 CEG37942.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PMP22_Claudin PF00822.20 CEG37943.1 - 0.12 12.3 0.1 6.3 6.6 0.0 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family PCI PF01399.27 CEG37944.1 - 4.9e-12 46.3 3.5 2.3e-11 44.1 0.5 2.5 2 1 0 2 2 2 1 PCI domain DUF4477 PF14780.6 CEG37944.1 - 0.016 14.8 0.2 0.016 14.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) TyeA PF09059.10 CEG37944.1 - 0.057 13.5 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 TyeA DUF3883 PF13020.6 CEG37945.1 - 9.9e-21 73.6 0.6 2.2e-20 72.5 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 CEG37945.1 - 9.7e-05 22.2 0.1 0.00029 20.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.19 CEG37947.1 - 7.3e-52 175.3 0.0 2e-51 173.8 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEG37947.1 - 3.8e-30 104.3 0.1 7.1e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 CEG37947.1 - 4.2e-07 29.6 0.1 1.6e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 CEG37947.1 - 0.00012 22.3 0.0 0.00059 20.0 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Aminotran_5 PF00266.19 CEG37947.1 - 0.00022 20.3 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V IlvN PF07991.12 CEG37947.1 - 0.0014 18.2 0.1 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CEG37947.1 - 0.086 13.4 0.2 0.66 10.6 0.0 2.6 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent ACT_7 PF13840.6 CEG37947.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain WD40 PF00400.32 CEG37948.1 - 8.8e-28 96.0 30.8 9e-05 23.2 0.4 12.1 11 2 1 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG37948.1 - 3.2e-07 30.5 0.1 8.1 6.8 0.0 6.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CEG37948.1 - 0.0025 17.2 1.0 0.0079 15.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CEG37948.1 - 0.0072 16.8 0.1 0.022 15.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG37948.1 - 0.011 15.2 0.2 0.027 14.0 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CEG37948.1 - 0.055 13.4 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain cNMP_binding PF00027.29 CEG37949.1 - 3.8e-10 39.7 0.0 6.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CLAMP PF14769.6 CEG37950.1 - 0.00035 21.0 0.6 0.022 15.2 0.6 2.4 1 1 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 CAP_C PF08603.11 CEG37951.1 - 2.7e-54 183.0 1.1 4.1e-54 182.5 1.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CEG37951.1 - 2.7e-51 174.9 0.3 6e-49 167.2 0.0 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CEG37951.1 - 0.00099 18.8 2.2 0.003 17.3 2.2 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C RNA_pol_Rpb1_5 PF04998.17 CEG37952.1 - 2.3e-101 338.7 0.1 3.9e-101 338.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CEG37952.1 - 1.8e-94 316.6 0.0 4.9e-94 315.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CEG37952.1 - 2.7e-74 248.9 0.3 5.7e-74 247.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CEG37952.1 - 1.7e-65 220.5 1.4 3.1e-65 219.6 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CEG37952.1 - 2.1e-51 173.5 1.0 3.9e-51 172.6 1.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CEG37952.1 - 3.8e-46 156.9 0.0 1.1e-45 155.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CEG37952.1 - 8.3e-34 115.8 0.0 2.1e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CEG37952.1 - 1.6e-09 37.6 135.3 0.019 15.3 14.0 8.8 9 0 0 9 9 9 7 RNA polymerase Rpb1 C-terminal repeat zf-BED PF02892.15 CEG37952.1 - 0.67 10.0 3.5 16 5.6 1.0 2.5 2 0 0 2 2 2 0 BED zinc finger Sas10_Utp3 PF04000.15 CEG37953.1 - 1.6e-14 54.3 0.6 1.4e-13 51.2 0.1 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TolA PF06519.11 CEG37954.1 - 0.07 13.3 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 TolA C-terminal P2X_receptor PF00864.19 CEG37954.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 ATP P2X receptor cNMP_binding PF00027.29 CEG37956.1 - 7.1e-13 48.4 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CEG37956.1 - 1.1e-10 41.2 10.7 2.4e-10 40.1 10.7 1.6 1 1 0 1 1 1 1 Ion transport protein Sugarporin_N PF11471.8 CEG37956.1 - 0.18 11.8 1.9 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension His_Phos_2 PF00328.22 CEG37958.1 - 1.7e-21 77.0 0.3 2.3e-21 76.6 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pur_ac_phosph_N PF16656.5 CEG37960.1 - 2.5e-19 69.7 0.0 5.4e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 CEG37960.1 - 2.7e-13 50.9 4.0 2.7e-13 50.9 4.0 2.0 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG37960.1 - 2.7e-13 50.6 0.8 1e-12 48.7 0.8 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C DUF1743 PF08489.11 CEG37962.1 - 0.064 13.3 0.0 0.36 10.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1743) FAINT PF04385.15 CEG37962.1 - 0.075 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, DUF529 Pkinase PF00069.25 CEG37963.1 - 9.9e-57 192.3 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37963.1 - 4.4e-25 88.5 0.0 5.1e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG37963.1 - 4.3e-07 30.1 0.0 4.7e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG37963.1 - 4.4e-05 22.9 0.0 7.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG37963.1 - 0.0013 17.6 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG37963.1 - 0.0027 16.7 0.4 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CEG37963.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 CEG37964.1 - 1e-41 141.8 0.0 1.5e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG37964.1 - 0.037 14.3 1.9 0.038 14.3 0.0 2.0 2 1 0 2 2 2 0 RWD domain UFC1 PF08694.11 CEG37964.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 FA_hydroxylase PF04116.13 CEG37966.1 - 5.6e-18 65.6 12.4 8.9e-18 64.9 12.4 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily APG9 PF04109.16 CEG37967.1 - 1.8e-145 485.6 14.4 2.2e-145 485.4 14.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 POT1 PF02765.17 CEG37968.1 - 9.2e-20 70.9 0.0 3e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Pkinase PF00069.25 CEG37971.1 - 3.1e-72 243.1 0.0 3.6e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37971.1 - 9.4e-37 126.7 0.0 1.2e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEG37971.1 - 1.8e-06 28.6 2.6 3.5e-06 27.6 2.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CEG37971.1 - 6.3e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG37971.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG37971.1 - 0.00038 19.5 0.2 0.00054 19.0 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEG37971.1 - 0.0058 16.6 0.1 0.014 15.3 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEG37971.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CEG37971.1 - 0.039 13.6 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEG37971.1 - 0.051 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CN_hydrolase PF00795.22 CEG37972.1 - 1.6e-34 119.4 0.0 2.2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CEG37972.1 - 9e-24 83.9 0.0 3.1e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase ICAM_N PF03921.14 CEG37974.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain RSD-2 PF07547.13 CEG37974.1 - 0.09 13.3 0.0 0.096 13.2 0.0 1.1 1 0 0 1 1 1 0 RSD-2 N-terminal domain DUF3330 PF11809.8 CEG37975.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) USP7_ICP0_bdg PF12436.8 CEG37976.1 - 8.3e-53 179.2 0.0 8.3e-50 169.3 0.0 2.7 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 CEG37976.1 - 4.7e-49 167.2 0.5 8.8e-49 166.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CEG37976.1 - 6.8e-31 107.6 0.0 4.1e-29 101.8 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 CEG37976.1 - 8.6e-23 81.4 0.5 1.9e-22 80.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG37976.1 - 0.0044 16.7 0.0 1.7 8.5 0.0 3.7 3 0 0 3 3 3 1 Ubiquitin family Peptidase_C98 PF15499.6 CEG37976.1 - 0.056 12.9 0.6 0.14 11.6 0.6 1.7 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Rad60-SLD PF11976.8 CEG37976.1 - 0.066 13.1 0.1 21 5.1 0.0 4.6 4 2 1 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like TRP PF06011.12 CEG37977.1 - 1.6e-07 30.5 23.8 4.1e-06 25.8 7.2 3.6 2 1 1 3 3 3 2 Transient receptor potential (TRP) ion channel FANCA_interact PF15751.5 CEG37977.1 - 0.26 11.8 6.4 0.61 10.6 6.4 1.6 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain Dynamitin PF04912.14 CEG37978.1 - 3.5e-49 168.1 16.1 4.7e-49 167.8 16.1 1.1 1 0 0 1 1 1 1 Dynamitin Phasin_2 PF09361.10 CEG37978.1 - 0.31 11.3 11.1 0.26 11.6 0.3 3.1 3 0 0 3 3 3 0 Phasin protein CLZ PF16526.5 CEG37978.1 - 0.71 10.3 16.8 0.22 11.9 0.7 5.0 4 2 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snf7 PF03357.21 CEG37978.1 - 1.7 8.2 11.8 0.38 10.3 6.3 2.7 2 1 0 2 2 2 0 Snf7 Hexapep PF00132.24 CEG37979.1 - 1.4e-15 56.3 14.6 2e-06 27.3 0.1 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEG37979.1 - 5.3e-06 26.1 11.7 0.011 15.4 2.5 4.2 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase COMM_domain PF07258.14 CEG37980.1 - 1.1e-08 35.0 1.4 1.2e-08 35.0 1.4 1.0 1 0 0 1 1 1 1 COMM domain ABC_tran PF00005.27 CEG37981.1 - 4.2e-39 134.2 0.0 8.1e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CEG37981.1 - 5.3e-14 51.8 5.8 1.5e-13 50.3 5.8 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CEG37981.1 - 2.9e-11 43.2 4.1 0.0003 20.3 1.3 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEG37981.1 - 4.3e-10 39.9 7.7 0.067 13.0 0.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CEG37981.1 - 2e-07 30.5 2.9 2e-07 30.5 2.9 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 CEG37981.1 - 5.2e-07 30.2 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CEG37981.1 - 1.9e-06 27.8 1.7 0.029 14.1 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain Fer4_6 PF12837.7 CEG37981.1 - 1.4e-05 24.9 2.4 1.4e-05 24.9 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 CEG37981.1 - 1.9e-05 25.1 0.0 0.2 12.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CEG37981.1 - 4.8e-05 23.3 0.9 0.028 14.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Fer4_10 PF13237.6 CEG37981.1 - 5.4e-05 23.2 8.5 0.0011 19.0 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_22 PF13401.6 CEG37981.1 - 5.5e-05 23.5 0.2 0.037 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEG37981.1 - 7.9e-05 22.3 0.1 0.36 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG37981.1 - 0.00015 21.7 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SRP54 PF00448.22 CEG37981.1 - 0.00027 20.6 1.3 0.067 12.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 CEG37981.1 - 0.00063 19.7 1.0 0.00063 19.7 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.14 CEG37981.1 - 0.0008 19.4 0.4 0.25 11.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Fer4_21 PF14697.6 CEG37981.1 - 0.00081 19.5 11.7 0.0019 18.3 11.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 CEG37981.1 - 0.00098 19.1 0.2 0.062 13.3 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CEG37981.1 - 0.0011 19.3 0.1 2 8.8 0.0 3.4 4 0 0 4 4 3 1 RNA helicase AAA_33 PF13671.6 CEG37981.1 - 0.0014 18.8 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CEG37981.1 - 0.0016 19.0 5.5 0.024 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 CEG37981.1 - 0.0019 18.2 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 CEG37981.1 - 0.002 17.9 0.3 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEG37981.1 - 0.003 17.8 0.1 0.9 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CEG37981.1 - 0.0034 17.9 1.5 0.0034 17.9 1.5 2.5 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEG37981.1 - 0.0043 17.2 11.5 0.01 16.0 11.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CEG37981.1 - 0.0055 16.4 0.1 3.7 7.2 0.0 2.8 2 0 0 2 2 2 1 Thymidylate kinase Fer4_16 PF13484.6 CEG37981.1 - 0.0061 17.5 0.1 0.0061 17.5 0.1 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_18 PF13238.6 CEG37981.1 - 0.0066 17.0 0.1 5.4 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain VirE PF05272.11 CEG37981.1 - 0.0093 15.7 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_30 PF13604.6 CEG37981.1 - 0.016 15.0 0.2 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CEG37981.1 - 0.029 13.6 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CEG37981.1 - 0.031 14.2 0.6 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 CEG37981.1 - 0.036 14.2 0.6 9 6.4 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 CEG37981.1 - 0.056 12.8 0.1 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI BON PF04972.17 CEG37981.1 - 0.06 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 BON domain AAA_7 PF12775.7 CEG37981.1 - 0.061 12.8 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 CEG37981.1 - 0.081 12.6 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 CEG37981.1 - 0.1 12.5 0.8 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 CEG37981.1 - 0.23 10.4 0.1 2.5 7.0 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 CEG37981.1 - 0.23 10.0 1.3 0.51 8.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain Fer4_4 PF12800.7 CEG37981.1 - 1.3 9.7 14.9 0.23 12.0 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CEG37981.1 - 3.2 8.3 10.9 0.43 11.1 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CEG37981.1 - 6.1 7.5 12.0 0.13 12.9 1.5 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-C2H2_4 PF13894.6 CEG37982.1 - 1.8e-06 28.3 21.6 0.00051 20.7 0.1 6.6 7 1 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEG37982.1 - 0.003 17.5 0.1 0.003 17.5 0.1 4.8 5 1 1 6 6 6 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG37982.1 - 0.026 15.0 0.1 0.026 15.0 0.1 6.5 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-BED PF02892.15 CEG37982.1 - 0.06 13.4 2.4 4.1 7.5 0.1 3.0 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 CEG37982.1 - 0.96 9.8 0.0 0.96 9.8 0.0 5.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 CEG37982.1 - 6.3 7.0 5.8 27 5.0 0.1 3.1 3 0 0 3 3 3 0 Zic proteins zinc finger domain WH2 PF02205.20 CEG37983.1 - 9.2e-11 41.2 6.5 8.1e-09 35.0 1.3 2.6 2 0 0 2 2 2 2 WH2 motif WW PF00397.26 CEG37983.1 - 9.4e-07 28.8 4.0 1.5e-06 28.1 4.0 1.4 1 0 0 1 1 1 1 WW domain CAP_N PF01213.19 CEG37983.1 - 0.62 9.5 6.7 0.11 11.9 0.6 2.2 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal RNase_J_C PF17770.1 CEG37984.1 - 0.022 15.8 1.3 0.075 14.1 1.3 2.0 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain Dynein_C PF18199.1 CEG37984.1 - 0.022 14.0 4.1 0.032 13.4 4.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain DUF3194 PF11419.8 CEG37984.1 - 0.025 14.9 0.3 0.052 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) IFT46_B_C PF12317.8 CEG37984.1 - 0.47 10.2 5.0 0.77 9.4 5.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal SpoU_methylase PF00588.19 CEG37985.1 - 1e-30 106.8 0.0 1.5e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CEG37985.1 - 1.1e-10 41.6 0.1 3.7e-10 39.9 0.1 1.8 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HEAT_2 PF13646.6 CEG37986.1 - 0.032 14.6 1.0 12 6.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 CEG37986.1 - 0.15 12.4 0.8 12 6.5 0.3 3.2 2 0 0 2 2 2 0 HEAT repeat Pet191_N PF10203.9 CEG37986.1 - 2.7 8.4 9.9 27 5.2 0.1 3.9 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 EF-hand_1 PF00036.32 CEG37987.1 - 4.2e-07 29.1 0.2 9.6e-07 27.9 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CEG37987.1 - 1.6e-05 25.3 1.5 3.7e-05 24.1 0.3 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CEG37987.1 - 1.7e-05 24.6 0.1 4e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG37987.1 - 4.2e-05 23.1 0.1 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CEG37987.1 - 0.013 14.9 2.3 0.017 14.6 0.9 2.0 2 0 0 2 2 2 0 EF hand Fib_alpha PF08702.10 CEG37987.1 - 0.34 11.1 2.4 0.42 10.8 1.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_16 PF13432.6 CEG37988.1 - 4.3e-13 49.7 11.4 0.015 15.9 0.0 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG37988.1 - 2.1e-12 47.1 26.8 2.7e-06 27.5 5.8 6.9 5 2 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEG37988.1 - 6.7e-12 45.7 19.5 0.0025 18.3 4.5 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEG37988.1 - 2.9e-09 37.0 9.8 0.0066 17.2 0.2 8.2 6 2 4 10 10 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG37988.1 - 4.4e-09 35.8 28.5 0.12 12.5 0.2 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG37988.1 - 5.6e-09 36.2 20.1 0.0035 17.6 0.5 8.3 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 CEG37988.1 - 5.7e-09 36.1 23.4 0.013 16.1 0.1 9.0 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG37988.1 - 4.1e-06 26.4 14.6 0.54 10.4 0.8 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG37988.1 - 4.7e-06 26.2 36.5 0.068 13.0 0.9 9.9 12 0 0 12 12 11 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG37988.1 - 0.0026 17.8 17.7 1.2 9.3 0.2 6.2 5 1 2 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 CEG37988.1 - 0.0032 17.5 19.1 2 8.8 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Rubrerythrin PF02915.17 CEG37988.1 - 0.0097 16.3 6.0 0.046 14.1 1.0 3.1 3 0 0 3 3 3 1 Rubrerythrin TPR_4 PF07721.14 CEG37988.1 - 0.014 16.0 0.7 40 5.2 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 CEG37988.1 - 0.054 13.8 5.4 7.2 7.1 0.0 5.2 7 0 0 7 7 5 0 PPR repeat HrpB1_HrpK PF09613.10 CEG37988.1 - 0.074 12.7 1.7 3.5 7.3 0.0 3.4 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Acyl-CoA_ox_N PF14749.6 CEG37988.1 - 0.14 12.7 2.6 1 9.9 0.1 3.3 3 0 0 3 3 3 0 Acyl-coenzyme A oxidase N-terminal MIT PF04212.18 CEG37988.1 - 0.16 12.0 6.7 1.4 9.1 0.1 4.2 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain DUF5624 PF18538.1 CEG37988.1 - 0.49 10.5 2.4 25 5.0 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF5624) DUF3808 PF10300.9 CEG37988.1 - 0.59 8.8 11.1 0.18 10.5 0.8 3.5 2 2 1 4 4 4 0 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CEG37988.1 - 0.65 10.2 3.5 7.1 6.9 0.6 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEG37988.1 - 1.8 8.2 11.5 0.87 9.3 3.0 3.5 2 2 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEG37988.1 - 5.9 6.9 16.4 13 5.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 CEG37989.1 - 4.4e-52 177.1 0.0 6.5e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG37989.1 - 1.9e-25 89.7 0.0 3.2e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG37989.1 - 8.8e-06 25.8 0.0 0.0052 16.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Mad3_BUB1_I PF08311.12 CEG37989.1 - 3e-05 24.0 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kdo PF06293.14 CEG37989.1 - 9.8e-05 21.8 0.2 0.00017 21.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG37989.1 - 0.00048 19.5 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CEG37989.1 - 0.00056 19.6 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CEG37989.1 - 0.0016 17.3 0.0 0.003 16.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG37989.1 - 0.047 12.6 0.2 0.079 11.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AAA_12 PF13087.6 CEG37990.1 - 5.1e-31 107.9 0.0 8.7e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG37990.1 - 5.9e-18 65.6 0.0 1.6e-07 31.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CEG37990.1 - 0.0015 18.3 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CEG37990.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-RING_UBOX PF13445.6 CEG37991.1 - 0.016 15.2 0.5 0.016 15.2 0.5 4.7 5 0 0 5 5 5 0 RING-type zinc-finger Pectate_lyase PF03211.13 CEG37991.1 - 0.069 12.7 0.8 0.09 12.3 0.1 1.5 2 0 0 2 2 2 0 Pectate lyase AAA PF00004.29 CEG37992.1 - 8e-15 55.4 0.1 7.7e-11 42.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG37992.1 - 1.1e-07 32.2 0.6 0.19 12.0 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 CEG37992.1 - 4.3e-06 26.8 1.5 2.2e-05 24.5 1.5 2.3 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 CEG37992.1 - 8.6e-06 25.8 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ResIII PF04851.15 CEG37992.1 - 4.9e-05 23.4 1.1 0.0012 18.8 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CEG37992.1 - 5.7e-05 23.6 0.0 0.021 15.2 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CEG37992.1 - 6.3e-05 22.4 0.0 0.23 10.8 0.0 3.0 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CEG37992.1 - 6.4e-05 22.7 0.0 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEG37992.1 - 0.00037 21.1 0.7 0.055 14.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 CEG37992.1 - 0.00059 19.6 0.1 1.7 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 CEG37992.1 - 0.00066 19.8 0.0 0.089 12.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 CEG37992.1 - 0.00094 19.0 0.0 0.19 11.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEG37992.1 - 0.0011 18.5 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CEG37992.1 - 0.0014 19.0 0.0 0.5 10.8 0.0 3.0 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 CEG37992.1 - 0.0018 18.2 0.2 0.97 9.3 0.0 2.8 2 1 0 2 2 2 1 NTPase MCM PF00493.23 CEG37992.1 - 0.0019 17.4 0.3 0.024 13.7 0.1 2.5 3 0 0 3 3 3 1 MCM P-loop domain AAA_19 PF13245.6 CEG37992.1 - 0.0019 18.5 0.4 2.1 8.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CEG37992.1 - 0.0024 17.6 0.2 1.2 8.8 0.2 3.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 CEG37992.1 - 0.0034 17.6 0.0 1.3 9.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain TniB PF05621.11 CEG37992.1 - 0.0042 16.5 0.0 4 6.8 0.0 2.9 2 1 1 3 3 3 1 Bacterial TniB protein IstB_IS21 PF01695.17 CEG37992.1 - 0.0055 16.5 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 CEG37992.1 - 0.021 15.0 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CEG37992.1 - 0.029 13.6 0.1 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CEG37992.1 - 0.044 14.3 0.7 1.8 9.1 0.0 3.1 2 1 1 3 3 3 0 ABC transporter DUF3987 PF13148.6 CEG37992.1 - 0.054 12.5 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DNA_pol3_delta2 PF13177.6 CEG37992.1 - 0.08 12.7 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit NACHT PF05729.12 CEG37992.1 - 0.1 12.5 0.4 2.4 8.0 0.0 2.9 2 1 1 3 3 3 0 NACHT domain Viral_helicase1 PF01443.18 CEG37992.1 - 0.11 12.3 0.3 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CEG37992.1 - 0.11 12.2 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEG37992.1 - 0.14 12.6 0.1 7 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG37993.1 - 3.6e-35 121.3 2.2 2.1e-14 54.1 0.0 4.8 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 CEG37993.1 - 1.6e-16 60.2 0.0 0.00037 20.6 0.0 3.8 3 0 0 3 3 3 3 AAA lid domain RuvB_N PF05496.12 CEG37993.1 - 2.4e-11 43.6 0.7 0.00016 21.4 0.0 3.9 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG37993.1 - 6.1e-08 33.0 2.2 3 8.1 0.1 6.4 4 2 0 5 5 5 1 AAA domain AAA_2 PF07724.14 CEG37993.1 - 1.9e-07 31.4 0.1 0.1 12.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CEG37993.1 - 5e-07 29.3 4.1 0.075 12.4 0.1 4.2 2 2 1 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CEG37993.1 - 5.2e-07 29.6 7.0 0.0023 17.7 0.5 3.5 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CEG37993.1 - 4.1e-06 26.8 2.3 0.1 12.6 0.1 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG37993.1 - 1.1e-05 25.9 7.3 0.019 15.4 0.1 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_33 PF13671.6 CEG37993.1 - 1.6e-05 25.1 2.0 0.097 12.8 0.2 3.6 4 1 0 4 4 3 2 AAA domain Viral_helicase1 PF01443.18 CEG37993.1 - 2.2e-05 24.3 0.6 0.2 11.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CEG37993.1 - 4.1e-05 24.1 0.6 0.16 12.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEG37993.1 - 0.00025 21.4 0.3 1.7 9.1 0.1 3.2 3 0 0 3 3 2 2 RNA helicase Torsin PF06309.11 CEG37993.1 - 0.00037 20.6 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Torsin Sigma54_activat PF00158.26 CEG37993.1 - 0.00045 20.0 4.9 0.46 10.2 0.3 4.6 3 2 0 3 3 3 1 Sigma-54 interaction domain AAA_11 PF13086.6 CEG37993.1 - 0.00046 20.1 0.2 0.8 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEG37993.1 - 0.00096 19.2 0.2 2.6 8.1 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CEG37993.1 - 0.0037 17.6 9.0 0.8 10.0 0.4 4.4 4 2 1 5 5 5 2 AAA domain AAA_28 PF13521.6 CEG37993.1 - 0.0039 17.5 4.5 0.91 9.7 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 CEG37993.1 - 0.0043 16.9 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CEG37993.1 - 0.0046 16.1 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TrwB_AAD_bind PF10412.9 CEG37993.1 - 0.0075 15.2 0.9 0.62 8.9 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Aminotran_1_2 PF00155.21 CEG37993.1 - 0.0087 15.3 0.1 3 6.9 0.0 2.4 2 0 0 2 2 2 1 Aminotransferase class I and II AAA_7 PF12775.7 CEG37993.1 - 0.019 14.5 0.2 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region APS_kinase PF01583.20 CEG37993.1 - 0.024 14.5 0.4 6.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 CEG37993.1 - 0.025 14.3 0.6 12 5.6 0.1 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 CEG37993.1 - 0.031 13.7 0.7 2.9 7.3 0.1 2.7 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.14 CEG37993.1 - 0.035 13.3 0.2 6.2 5.9 0.0 2.7 3 0 0 3 3 2 0 PIF1-like helicase ResIII PF04851.15 CEG37993.1 - 0.035 14.1 0.3 27 4.7 0.0 4.3 4 2 2 6 6 6 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CEG37993.1 - 0.035 13.8 0.0 6.1 6.5 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein PRK PF00485.18 CEG37993.1 - 0.037 13.8 0.9 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 CEG37993.1 - 0.043 13.3 0.4 10 5.5 0.0 2.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 CEG37993.1 - 0.043 14.3 0.6 12 6.4 0.1 3.0 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 CEG37993.1 - 0.088 12.1 0.1 17 4.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 CEG37993.1 - 0.12 12.5 0.9 13 5.9 0.2 2.6 2 0 0 2 2 2 0 Shikimate kinase CdiI_N PF18228.1 CEG37993.1 - 0.12 12.2 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 CdiI N-terminal domain CbiA PF01656.23 CEG37993.1 - 0.18 11.9 0.7 19 5.3 0.1 2.9 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 CEG37993.1 - 0.19 11.7 0.3 8.2 6.3 0.1 2.7 2 0 0 2 2 2 0 NTPase Mur_ligase_M PF08245.12 CEG37993.1 - 0.19 11.7 4.0 3.8 7.4 0.4 2.5 2 0 0 2 2 2 0 Mur ligase middle domain DUF2075 PF09848.9 CEG37993.1 - 0.25 10.5 4.8 14 4.8 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CEG37993.1 - 0.72 9.8 2.5 28 4.6 0.1 3.0 3 0 0 3 3 3 0 NACHT domain DUF3987 PF13148.6 CEG37993.1 - 3.2 6.7 6.2 7.3 5.5 0.0 3.2 4 0 0 4 4 3 0 Protein of unknown function (DUF3987) FliT PF05400.13 CEG37993.1 - 6.9 7.6 9.7 1.4 9.8 2.3 3.1 3 0 0 3 3 3 0 Flagellar protein FliT zf-MYND PF01753.18 CEG37994.1 - 4.3e-11 42.7 15.2 7.6e-11 41.9 15.2 1.4 1 0 0 1 1 1 1 MYND finger Xylo_C PF12529.8 CEG37994.1 - 0.0095 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Xylosyltransferase C terminal CPSase_L_D3 PF02787.19 CEG37994.1 - 0.057 13.8 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain zf-HIT PF04438.16 CEG37994.1 - 0.065 13.1 9.3 0.11 12.3 9.3 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 CEG37994.1 - 1.4 9.2 9.9 3.3 8.1 9.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RTP1_C1 PF10363.9 CEG37998.1 - 6.3e-29 100.4 0.5 1.6e-25 89.4 0.1 2.9 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 SNARE PF05739.19 CEG37998.1 - 2.6e-15 56.1 1.0 1.9e-14 53.4 0.1 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CEG37998.1 - 5.2e-06 26.3 12.8 2.7e-05 23.9 12.8 2.2 1 1 0 1 1 1 1 Syntaxin RTP1_C2 PF10304.9 CEG37998.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 CEG37998.1 - 0.25 11.8 7.0 0.1 13.0 0.3 3.5 4 0 0 4 4 4 0 HEAT repeats DUF2951 PF11166.8 CEG37998.1 - 0.6 10.4 7.3 0.11 12.7 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Glyco_hydro_2 PF00703.21 CEG37999.1 - 2.7e-08 34.4 0.0 6.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 CEG37999.1 - 2.3e-07 30.9 0.2 6.4e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 CEG37999.1 - 3.7e-07 30.7 0.4 1.5e-06 28.7 0.0 2.3 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 CEG37999.1 - 2.7e-06 27.0 0.8 7.6e-06 25.6 0.4 1.9 2 0 0 2 2 2 1 Ig-fold domain CENP_C_N PF15622.6 CEG38001.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal bZIP_Maf PF03131.17 CEG38001.1 - 0.3 11.6 11.0 0.88 10.1 10.9 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor Nefa_Nip30_N PF10187.9 CEG38001.1 - 3.8 7.9 7.0 12 6.4 6.1 1.9 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PALP PF00291.25 CEG38004.1 - 2.4e-40 138.8 0.0 2.7e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lebercilin PF15619.6 CEG38007.1 - 0.0014 18.3 30.0 0.0014 18.3 30.0 10.8 3 1 6 10 10 10 2 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 CEG38007.1 - 0.0017 19.0 1.2 0.0017 19.0 1.2 20.9 9 5 13 22 22 22 4 SlyX Tropomyosin_1 PF12718.7 CEG38007.1 - 0.0028 17.8 19.4 0.0028 17.8 19.4 14.3 2 1 12 14 14 14 5 Tropomyosin like BRE1 PF08647.11 CEG38007.1 - 0.0053 16.8 12.1 0.0053 16.8 12.1 18.9 4 2 11 18 18 18 6 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 CEG38007.1 - 0.44 9.4 244.1 0.065 12.1 16.0 11.3 3 2 9 12 12 12 0 Spc7 kinetochore protein DUF3410 PF11890.8 CEG38007.1 - 1.6 8.6 9.8 0.1 12.4 0.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) ATG16 PF08614.11 CEG38007.1 - 3.9 7.6 275.3 0.18 12.0 13.7 14.1 1 1 10 13 13 13 0 Autophagy protein 16 (ATG16) DUF155 PF02582.14 CEG38009.1 - 6.3e-38 130.6 0.2 9.2e-38 130.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GCD14 PF08704.10 CEG38010.1 - 8.6e-81 271.2 0.0 1e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CEG38010.1 - 2e-09 37.4 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG38010.1 - 4.8e-07 29.8 0.0 7.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CEG38010.1 - 6.6e-07 30.0 0.0 1.4e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEG38010.1 - 1.3e-05 26.2 0.0 2.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38010.1 - 3.5e-05 24.4 0.0 7.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CEG38010.1 - 4.4e-05 23.2 0.0 0.00012 21.7 0.0 1.6 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 CEG38010.1 - 0.00022 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14_N PF14801.6 CEG38010.1 - 0.0048 16.7 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_12 PF08242.12 CEG38010.1 - 0.025 15.3 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 CEG38010.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase HABP4_PAI-RBP1 PF04774.15 CEG38011.1 - 0.0036 18.1 1.3 0.0039 18.0 1.3 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Ank_2 PF12796.7 CEG38012.1 - 2e-16 60.4 0.7 3.1e-05 24.5 0.0 2.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG38012.1 - 1.1e-15 57.8 1.7 1.1e-05 25.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG38012.1 - 4.8e-11 42.7 2.8 0.025 14.9 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG38012.1 - 9.7e-07 28.6 0.3 17 6.4 0.2 5.2 5 0 0 5 5 5 2 Ankyrin repeat DUF1843 PF08898.10 CEG38012.1 - 0.064 13.8 0.1 29 5.3 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) Ank_4 PF13637.6 CEG38013.1 - 1.7e-20 73.1 7.0 3.8e-06 27.3 0.3 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG38013.1 - 1.5e-12 47.9 0.1 2.7e-06 27.9 0.0 3.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG38013.1 - 2.1e-11 43.8 1.0 0.0087 16.4 0.1 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG38013.1 - 1.7e-06 27.9 0.0 20 6.2 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 CEG38013.1 - 0.049 14.1 0.0 96 3.7 0.0 4.5 1 1 2 3 3 3 0 Ankyrin repeat Y_phosphatase PF00102.27 CEG38014.1 - 1.9e-07 30.9 0.0 2.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG38014.1 - 2e-05 24.4 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CEG38014.1 - 0.00036 20.3 0.0 0.00058 19.6 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CEG38014.1 - 0.00098 19.3 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1623 PF07785.11 CEG38014.1 - 0.055 13.6 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Mid2 PF04478.12 CEG38014.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DNA_gyraseA_C PF03989.13 CEG38017.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Alk_phosphatase PF00245.20 CEG38019.1 - 0.0057 15.7 0.0 0.0068 15.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Peptidase_C2 PF00648.21 CEG38021.1 - 2.5e-11 43.1 1.7 1.3e-08 34.2 0.0 3.4 3 0 0 3 3 3 3 Calpain family cysteine protease Alk_phosphatase PF00245.20 CEG38022.1 - 1.9e-46 158.9 0.1 1.9e-46 158.9 0.1 1.7 2 0 0 2 2 2 1 Alkaline phosphatase zf-RING_2 PF13639.6 CEG38022.1 - 0.00078 19.7 6.1 0.00078 19.7 6.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG38022.1 - 0.001 19.3 4.5 0.0035 17.6 4.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG38022.1 - 0.0035 17.2 5.5 0.0035 17.2 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG38022.1 - 0.0059 16.5 3.5 0.0059 16.5 3.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG38022.1 - 0.0065 16.3 5.8 0.016 15.1 5.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEG38022.1 - 0.0076 16.1 1.9 0.02 14.7 1.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG38022.1 - 0.27 11.0 1.8 1.1 9.1 1.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger FAT PF02259.23 CEG38024.1 - 0.011 15.0 0.0 0.11 11.6 0.0 2.1 1 1 0 2 2 2 0 FAT domain V1R PF03402.14 CEG38026.1 - 0.011 15.4 1.2 0.015 14.9 0.8 1.3 1 1 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R DUF3397 PF11877.8 CEG38026.1 - 0.013 15.6 0.5 0.02 15.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3397) Cytochrom_B_C PF00032.17 CEG38026.1 - 0.21 11.9 2.8 0.34 11.2 2.8 1.3 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Atg14 PF10186.9 CEG38027.1 - 0.0011 18.2 0.1 0.0014 17.8 0.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_2 PF07727.14 CEG38027.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CC2D2AN-C2 PF15625.6 CEG38029.1 - 0.03 14.0 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Carn_acyltransf PF00755.20 CEG38030.1 - 1.9e-200 667.5 0.0 2.1e-200 667.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DCD PF06559.11 CEG38030.1 - 0.094 11.5 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Cadherin_5 PF17892.1 CEG38030.1 - 0.19 11.7 0.4 0.48 10.4 0.2 1.8 1 1 0 1 1 1 0 Cadherin-like domain PDEase_I PF00233.19 CEG38031.1 - 8.3e-69 231.9 1.0 3.7e-67 226.5 0.1 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CEG38031.1 - 6.9e-07 30.0 0.0 4e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 CEG38031.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 GAF domain E1-E2_ATPase PF00122.20 CEG38033.1 - 7.9e-46 155.9 0.5 7.9e-46 155.9 0.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEG38033.1 - 3e-16 60.4 0.0 1.6e-15 58.0 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG38033.1 - 6.3e-15 54.6 0.1 1.3e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG38033.1 - 0.0003 20.6 0.9 0.00045 20.0 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG38033.1 - 0.0066 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Phage_holin_Dp1 PF16938.5 CEG38033.1 - 0.093 12.9 2.1 1.4 9.1 0.9 2.7 2 0 0 2 2 2 0 Putative phage holin Dp-1 F-actin_cap_A PF01267.17 CEG38036.1 - 0.1 12.0 0.3 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 F-actin capping protein alpha subunit GAF_2 PF13185.6 CEG38037.1 - 2.2e-06 28.0 0.0 3.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain ABC1 PF03109.16 CEG38038.1 - 8.4e-21 74.3 0.0 1.6e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CEG38038.1 - 3e-08 33.4 0.0 6.8e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CEG38038.1 - 0.0012 18.8 1.7 0.006 16.5 0.2 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CEG38038.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Peptidase_M13_N PF05649.13 CEG38039.1 - 9.5e-67 226.3 0.0 1.3e-66 225.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEG38039.1 - 9.9e-64 214.7 1.5 3.5e-44 150.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M13 PWI PF01480.17 CEG38040.1 - 3.2e-26 91.4 0.1 6e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 PWI domain Pro-kuma_activ PF09286.11 CEG38041.1 - 2e-22 80.1 0.0 5.2e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CEG38041.1 - 0.0001 21.7 0.0 0.00038 19.8 0.0 1.9 2 0 0 2 2 2 1 Subtilase family DUF5609 PF18429.1 CEG38041.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) NIF PF03031.18 CEG38043.1 - 0.022 14.5 0.1 0.072 12.9 0.0 1.9 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase NPP1 PF05630.11 CEG38045.1 - 9.9e-64 215.1 0.0 1.4e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) TcdB_N PF12918.7 CEG38048.1 - 0.11 12.8 1.1 0.3 11.4 1.1 1.7 1 1 0 1 1 1 0 TcdB toxin N-terminal helical domain Robl_LC7 PF03259.17 CEG38049.1 - 4.6e-24 84.0 0.0 1.3e-23 82.5 0.0 1.9 1 0 0 1 1 1 1 Roadblock/LC7 domain Arm PF00514.23 CEG38049.1 - 2.9e-18 65.2 23.7 0.00086 19.3 0.1 9.3 8 1 1 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG38049.1 - 2.6e-07 31.0 5.0 0.02 15.4 0.5 5.1 4 1 0 4 4 4 2 HEAT-like repeat NopRA1 PF16201.5 CEG38049.1 - 0.00028 20.6 0.0 0.049 13.2 0.0 3.1 2 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 LAMTOR5 PF16672.5 CEG38049.1 - 0.00081 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 HEAT_2 PF13646.6 CEG38049.1 - 0.0014 19.0 0.5 1 9.8 0.1 3.9 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 CEG38049.1 - 0.06 13.6 6.5 0.17 12.2 0.0 4.6 6 0 0 6 6 6 0 HEAT repeat Beta-lactamase PF00144.24 CEG38050.1 - 7.8e-07 28.6 0.1 8.6e-07 28.5 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CEG38050.1 - 1e-05 25.3 0.0 1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase enzyme family U-box PF04564.15 CEG38052.1 - 4.9e-20 71.5 0.1 1.3e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 CEG38052.1 - 2.4e-08 33.5 5.0 0.044 13.9 1.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG38052.1 - 2.4e-05 24.0 7.6 0.025 14.4 1.4 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.18 CEG38052.1 - 0.00028 20.9 0.8 0.7 10.0 0.0 3.3 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 CEG38052.1 - 0.00063 20.0 6.6 0.0041 17.4 0.3 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG38052.1 - 0.0047 17.4 2.7 6.8 7.3 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG38052.1 - 0.0058 17.2 9.5 1.9 9.2 0.3 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 CEG38052.1 - 0.0079 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_21 PF09976.9 CEG38052.1 - 0.011 15.4 0.1 17 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 CEG38052.1 - 0.048 13.7 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 zf-Nse PF11789.8 CEG38052.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ANAPC3 PF12895.7 CEG38052.1 - 0.056 13.7 1.8 0.21 11.8 1.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CEG38052.1 - 0.076 12.7 0.5 5 6.8 0.0 3.0 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 CEG38052.1 - 0.083 12.8 0.2 2 8.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG38052.1 - 0.086 13.1 2.4 1.3 9.5 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG38052.1 - 0.23 12.2 9.6 0.4 11.4 0.4 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38052.1 - 0.26 11.0 1.1 11 5.8 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 CEG38052.1 - 2.3 9.3 8.6 32 5.7 0.3 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat APG5 PF04106.12 CEG38053.1 - 8e-53 179.4 0.0 9.9e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Glyco_hydro_17 PF00332.18 CEG38054.1 - 4.2e-05 23.3 0.2 0.00012 21.8 0.1 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_17 PF00332.18 CEG38056.1 - 0.0003 20.5 0.4 0.00056 19.6 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 MtN3_slv PF03083.16 CEG38058.1 - 1e-26 92.7 23.0 9.4e-19 67.2 4.7 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange Phtf-FEM1B_bdg PF12129.8 CEG38058.1 - 8.3 6.2 7.6 1.3 8.8 0.6 2.4 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor MtN3_slv PF03083.16 CEG38060.1 - 8.5e-22 77.0 27.4 4e-16 58.8 10.9 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange PetG PF02529.15 CEG38060.1 - 0.36 10.7 2.4 0.76 9.7 0.4 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF4407 PF14362.6 CEG38060.1 - 2.6 7.3 4.0 1.9 7.8 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCM PF00493.23 CEG38062.1 - 2.7e-66 222.9 0.0 5.6e-66 221.9 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 CEG38062.1 - 2e-12 47.4 6.3 5.7e-10 39.5 0.3 3.3 2 1 1 3 3 3 2 MCM AAA-lid domain Mg_chelatase PF01078.21 CEG38062.1 - 1e-07 31.6 0.0 2.2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG38062.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEG38062.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 CEG38062.1 - 0.087 12.7 3.3 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 AAA lid domain AAA_5 PF07728.14 CEG38062.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KBP_C PF12309.8 CEG38063.1 - 7.2e-77 259.3 0.1 2.3e-76 257.7 0.0 1.9 2 0 0 2 2 2 1 KIF-1 binding protein C terminal GAT PF03127.14 CEG38063.1 - 0.021 15.1 0.2 0.074 13.4 0.2 2.0 1 0 0 1 1 1 0 GAT domain Glyco_hydr_30_2 PF14587.6 CEG38064.1 - 3.1e-22 79.7 2.5 4.4e-22 79.2 2.5 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 CEG38064.1 - 2.2e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 CEG38064.1 - 0.029 14.6 0.2 0.082 13.1 0.2 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain MBT PF02820.18 CEG38064.1 - 0.19 12.1 0.3 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 mbt repeat NUDIX PF00293.28 CEG38065.1 - 7.9e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1d PF00750.19 CEG38066.1 - 3.1e-66 223.7 0.0 4.4e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CEG38066.1 - 9.5e-26 90.3 0.0 2.3e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CEG38066.1 - 2.5e-07 31.2 0.0 9.7e-06 26.1 0.0 2.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CEG38066.1 - 0.033 13.5 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 CEG38066.1 - 0.057 11.7 0.0 0.31 9.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) RNA_pol_L PF01193.24 CEG38066.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Sugar_tr PF00083.24 CEG38067.1 - 1.1e-68 232.2 21.3 5.2e-66 223.4 18.3 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG38067.1 - 9e-14 51.2 33.3 1.7e-07 30.5 11.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.8 CEG38067.1 - 7.4 6.4 7.4 0.69 9.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) LpxI_N PF17930.1 CEG38070.1 - 0.0058 16.5 0.0 0.0092 15.9 0.0 1.4 1 1 0 1 1 1 1 LpxI N-terminal domain EF-hand_1 PF00036.32 CEG38071.1 - 7e-07 28.4 7.0 0.11 12.1 0.6 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CEG38071.1 - 1.9e-06 27.3 5.0 0.096 12.7 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CEG38071.1 - 4.2e-05 23.9 2.7 0.026 14.9 2.7 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CEG38071.1 - 0.015 15.6 0.2 6.3 7.2 0.0 3.1 3 1 1 4 4 4 0 EF-hand domain EF-hand_8 PF13833.6 CEG38071.1 - 0.039 13.8 1.9 20 5.1 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair cIII PF08134.11 CEG38072.1 - 0.13 12.1 0.3 21 5.0 0.1 2.4 2 0 0 2 2 2 0 cIII protein family AA_kinase PF00696.28 CEG38074.1 - 6.7e-32 111.0 1.4 9e-32 110.6 1.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family Complex1_LYR_2 PF13233.6 CEG38075.1 - 3.6e-15 56.5 3.1 7e-15 55.5 3.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CEG38075.1 - 3.7e-06 26.9 1.2 3.7e-06 26.9 1.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CEG38075.1 - 0.022 15.3 1.1 0.036 14.7 1.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Urb2 PF10441.9 CEG38075.1 - 0.084 12.8 1.3 0.33 10.9 1.3 2.0 1 1 0 1 1 1 0 Urb2/Npa2 family Cnl2_NKP2 PF09447.10 CEG38075.1 - 0.087 13.0 0.7 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DENN PF02141.21 CEG38076.1 - 8.6e-30 104.1 2.3 1.7e-29 103.1 2.3 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 CEG38076.1 - 2.5e-15 56.8 10.9 3.3e-07 30.6 1.1 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain dDENN PF03455.19 CEG38076.1 - 0.1 12.6 0.0 0.48 10.5 0.0 2.3 1 0 0 1 1 1 0 dDENN domain UPF0176_N PF17773.1 CEG38078.1 - 1.3e-21 76.8 0.0 2.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CEG38078.1 - 4.2e-14 52.7 6.9 7.8e-14 51.8 6.9 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 CEG38078.1 - 4e-12 46.6 0.0 7.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain 2_5_RNA_ligase2 PF13563.6 CEG38079.1 - 0.011 15.7 0.3 0.022 14.7 0.3 1.4 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily DUF3989 PF13150.6 CEG38079.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) tRNA-synt_1d PF00750.19 CEG38080.1 - 2e-10 40.2 0.0 2.1e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (R) DUF3730 PF12530.8 CEG38082.1 - 0.083 12.5 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Foie-gras_1 PF11817.8 CEG38082.1 - 0.14 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 zf-BED PF02892.15 CEG38083.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 BED zinc finger CK_II_beta PF01214.18 CEG38083.1 - 0.017 14.9 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Choline_kinase PF01633.20 CEG38089.1 - 1.4e-51 175.1 0.0 2e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CEG38089.1 - 7.4e-14 52.2 0.0 1e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Voltage_CLC PF00654.20 CEG38091.1 - 2.2e-68 231.1 16.6 2.2e-68 231.1 16.6 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel Glyco_transf_28 PF03033.20 CEG38092.1 - 4.6e-26 91.5 0.2 4.8e-17 62.3 0.1 4.3 2 2 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 CEG38092.1 - 1.4e-06 28.5 0.0 1e-05 25.8 0.0 2.4 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 CEG38092.1 - 2.3e-05 23.4 0.0 4.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 CEG38092.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal zf-Tim10_DDP PF02953.15 CEG38094.1 - 8.9e-15 54.1 2.2 1.3e-14 53.6 2.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 CEG38095.1 - 1.6e-76 257.1 0.0 2e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38095.1 - 7.1e-39 133.6 0.3 3e-38 131.6 0.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG38095.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mg_trans_NIPA PF05653.14 CEG38096.1 - 1.3e-33 116.4 12.5 2.8e-19 69.4 1.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA TMEM234 PF10639.9 CEG38096.1 - 0.0034 17.4 0.1 0.011 15.7 0.1 1.9 1 0 0 1 1 1 1 Putative transmembrane family 234 7TMR-DISM_7TM PF07695.11 CEG38096.1 - 0.06 13.2 12.1 0.12 12.3 3.5 2.4 2 1 0 2 2 2 0 7TM diverse intracellular signalling UPF0060 PF02694.15 CEG38096.1 - 0.14 12.4 7.7 0.076 13.3 2.2 2.5 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family RIX1 PF08167.12 CEG38097.1 - 4.5e-13 49.4 2.6 4.5e-13 49.4 2.6 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Ribosomal_S21 PF01165.20 CEG38097.1 - 4.2 7.2 5.1 14 5.5 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein S21 Methyltransf_4 PF02390.17 CEG38103.1 - 1.6e-35 122.1 0.0 1.9e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 CEG38103.1 - 2.3e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38103.1 - 1.4e-06 28.9 0.0 2.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38103.1 - 7.9e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG38103.1 - 0.00013 22.6 0.0 0.00024 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG38103.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEG38103.1 - 0.01 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Foamy_virus_ENV PF03408.14 CEG38103.1 - 0.15 9.8 0.1 0.18 9.6 0.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Prenyltransf PF01255.19 CEG38104.1 - 2.5e-71 239.8 0.0 2.9e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cid2 PF09774.9 CEG38104.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Myb_DNA-binding PF00249.31 CEG38108.1 - 3.9e-59 196.6 17.5 5.7e-15 55.2 0.7 5.1 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG38108.1 - 5.7e-51 170.6 7.2 1.8e-16 60.1 0.0 5.1 4 1 1 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG38108.1 - 3.7e-10 39.6 0.1 0.15 12.0 0.0 5.0 2 2 3 5 5 5 4 Myb DNA-binding like Rap1_C PF11626.8 CEG38108.1 - 2.2e-08 34.1 0.0 0.5 10.5 0.1 4.2 2 1 2 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 CEG38108.1 - 7.2e-08 32.5 1.9 1.5 9.1 0.0 4.9 2 1 3 5 5 5 3 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CEG38108.1 - 4.1e-06 26.8 0.0 1 9.4 0.0 4.4 2 1 3 5 5 5 2 SLIDE Atg29_N PF18388.1 CEG38108.1 - 0.11 12.3 6.6 1.6 8.6 0.1 3.9 4 0 0 4 4 4 0 Atg29 N-terminal domain LexA_DNA_bind PF01726.16 CEG38108.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain DUF724 PF05266.14 CEG38109.1 - 0.032 14.1 2.4 0.046 13.5 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PPV_E1_N PF00524.18 CEG38109.1 - 0.22 11.9 6.3 0.33 11.4 6.3 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain DdrB PF12747.7 CEG38110.1 - 0.095 12.5 4.2 1.3 8.8 1.1 2.5 1 1 2 3 3 3 0 DdrB-like protein PH PF00169.29 CEG38111.1 - 0.0052 17.3 0.0 0.0083 16.6 0.0 1.4 1 0 0 1 1 1 1 PH domain SPX PF03105.19 CEG38112.1 - 1.8e-21 77.5 15.7 1.1e-11 45.3 5.4 3.1 1 1 2 3 3 3 3 SPX domain PEPcase PF00311.17 CEG38113.1 - 0.1 10.6 0.3 0.098 10.7 0.3 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Myb_DNA-binding PF00249.31 CEG38114.1 - 5.3e-10 39.3 0.1 1e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG38114.1 - 0.0051 17.0 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain GatB_Yqey PF02637.18 CEG38114.1 - 0.23 11.3 2.9 9.3 6.1 0.1 3.3 3 1 0 3 3 3 0 GatB domain PTS_EIIA_2 PF00359.22 CEG38115.1 - 0.028 14.3 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF1077 PF06417.12 CEG38118.1 - 4e-35 120.4 5.1 5.3e-35 120.0 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) BHD_1 PF10403.9 CEG38119.1 - 0.025 14.4 0.1 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 CBAH PF02275.18 CEG38121.1 - 7.1e-17 62.0 0.0 5e-16 59.2 0.0 2.4 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Voltage_CLC PF00654.20 CEG38124.1 - 1.3e-68 231.9 25.1 1.3e-68 231.9 25.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Abhydrolase_9_N PF15420.6 CEG38124.1 - 0.12 12.4 14.4 0.38 10.7 1.9 3.3 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus LRR_6 PF13516.6 CEG38125.1 - 0.00011 22.0 1.0 0.0057 16.6 0.1 3.5 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 CEG38125.1 - 0.0055 16.4 6.7 6.8 6.5 0.0 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 CEG38125.1 - 0.024 15.1 0.5 84 4.3 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 CEG38125.1 - 0.33 11.5 9.0 3 8.4 0.2 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 CEG38126.1 - 1.9e-99 333.1 11.6 3.1e-99 332.4 11.6 1.2 1 1 0 1 1 1 1 Presenilin TP6A_N PF04406.14 CEG38127.1 - 8e-15 54.6 0.0 1.6e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Tuberculin PF12198.8 CEG38129.1 - 0.014 15.4 1.5 0.022 14.8 1.5 1.3 1 0 0 1 1 1 0 Theoretical tuberculin protein DnaJ PF00226.31 CEG38130.1 - 1.3e-06 28.4 2.4 2.7e-06 27.4 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain PFU PF09070.11 CEG38130.1 - 0.00039 20.6 0.0 4.7 7.5 0.0 5.1 6 0 0 6 6 6 1 PFU (PLAA family ubiquitin binding) Pkinase PF00069.25 CEG38136.1 - 4.2e-61 206.6 0.0 1e-33 116.8 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38136.1 - 2.5e-39 135.1 0.0 7.6e-20 71.3 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG38136.1 - 0.012 15.0 1.1 7.5 5.8 0.0 3.4 4 0 0 4 4 4 0 Kinase-like C2 PF00168.30 CEG38138.1 - 8.5e-91 299.0 0.0 3.8e-18 65.7 0.0 8.4 8 0 0 8 8 8 8 C2 domain FerI PF08151.12 CEG38138.1 - 0.012 15.7 0.0 0.08 13.0 0.0 2.5 1 0 0 1 1 1 0 FerI (NUC094) domain Abhydrolase_6 PF12697.7 CEG38139.1 - 0.022 15.4 9.0 0.22 12.1 9.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mce4_CUP1 PF11887.8 CEG38140.1 - 0.0049 16.4 0.8 0.01 15.3 0.8 1.5 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative TPR_9 PF13371.6 CEG38140.1 - 0.15 12.3 3.5 1.2 9.4 1.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CX PF01705.19 CEG38140.1 - 0.71 10.5 3.1 2.7 8.6 0.7 2.5 2 0 0 2 2 2 0 CX module TPR_MLP1_2 PF07926.12 CEG38140.1 - 1 9.4 65.5 0.33 11.0 4.5 5.9 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CEG38140.1 - 6.7 6.7 63.9 0.073 13.1 5.0 5.2 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MPS2 PF17060.5 CEG38141.1 - 0.00017 21.0 1.4 0.0002 20.8 1.4 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 Kre28 PF17097.5 CEG38141.1 - 0.012 14.7 0.2 0.012 14.7 0.2 1.8 1 1 1 2 2 2 0 Spindle pole body component HIP1_clath_bdg PF16515.5 CEG38141.1 - 0.028 15.0 6.9 0.031 14.9 5.0 2.0 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COMP PF11598.8 CEG38141.1 - 0.045 14.2 0.9 0.1 13.1 0.9 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF4407 PF14362.6 CEG38141.1 - 0.19 11.0 2.6 0.27 10.6 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4240 PF14024.6 CEG38141.1 - 0.23 11.7 1.2 0.74 10.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4240) Csm1_N PF18504.1 CEG38141.1 - 0.25 11.7 9.2 0.32 11.4 3.3 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 CEG38141.1 - 2.9 8.0 9.0 4.3 7.4 9.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 CEG38141.1 - 3.3 7.8 10.3 0.67 10.1 0.9 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation Spc24 PF08286.11 CEG38141.1 - 4.6 7.5 7.3 3.5 7.9 0.4 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Ion_trans PF00520.31 CEG38143.1 - 5.6e-44 150.2 28.9 1.5e-24 86.6 9.5 2.3 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CEG38143.1 - 1.7e-24 85.6 12.3 5.8e-14 51.8 1.6 2.9 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 CEG38143.1 - 4.5e-18 65.1 0.2 3.6e-10 39.8 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain MBOAT PF03062.19 CEG38143.1 - 2.9e-05 23.6 1.5 7e-05 22.3 1.5 1.7 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family IRK PF01007.20 CEG38143.1 - 0.2 11.5 7.7 1.1 9.0 0.3 3.1 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Cytochrome-c551 PF10643.9 CEG38143.1 - 0.41 10.2 2.3 0.94 9.0 0.3 2.3 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 TMEM107 PF14995.6 CEG38143.1 - 0.75 10.2 4.4 0.4 11.1 0.5 2.5 2 0 0 2 2 2 0 Transmembrane protein DUF19 PF01579.18 CEG38144.1 - 0.03 14.1 1.2 0.057 13.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Aa_trans PF01490.18 CEG38145.1 - 6.6e-43 146.9 22.4 9.3e-43 146.5 22.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BT1 PF03092.16 CEG38148.1 - 2.1e-59 201.1 13.2 4e-32 111.2 1.8 3.8 1 1 2 3 3 3 3 BT1 family PUCC PF03209.15 CEG38148.1 - 0.00011 21.3 0.4 0.00023 20.3 0.4 1.5 1 0 0 1 1 1 1 PUCC protein MFS_3 PF05977.13 CEG38148.1 - 0.0022 16.5 1.1 0.0038 15.7 1.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Annexin PF00191.20 CEG38149.1 - 3.9e-60 199.8 3.0 6.7e-15 54.9 0.2 4.1 4 0 0 4 4 4 4 Annexin baeRF_family12 PF18856.1 CEG38149.1 - 0.0088 16.6 0.1 1.3 9.6 0.0 2.9 3 0 0 3 3 3 1 Bacterial archaeo-eukaryotic release factor family 12 Host_attach PF10116.9 CEG38149.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein required for attachment to host cells Pox_A14 PF05767.12 CEG38150.1 - 0.072 13.3 0.2 0.098 12.8 0.2 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 TMEM52 PF14979.6 CEG38150.1 - 0.87 9.5 6.4 0.75 9.7 5.5 1.3 1 1 0 1 1 1 0 Transmembrane 52 ABC_membrane PF00664.23 CEG38152.1 - 1.4e-59 202.0 35.9 2.2e-35 122.6 16.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG38152.1 - 6.4e-48 162.7 0.1 1.3e-26 93.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEG38152.1 - 1.6e-08 34.3 5.3 0.12 11.8 0.0 5.0 3 2 2 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEG38152.1 - 1.8e-07 31.3 3.9 0.048 13.5 0.6 4.8 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEG38152.1 - 6.8e-07 28.9 1.1 0.002 17.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEG38152.1 - 1.2e-06 29.0 0.0 0.00019 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEG38152.1 - 2.5e-06 27.5 0.3 0.006 16.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG38152.1 - 3.7e-06 27.0 0.1 0.15 12.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CEG38152.1 - 8.8e-06 26.4 2.9 0.016 15.7 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CEG38152.1 - 3.4e-05 23.4 0.1 0.0018 17.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 CEG38152.1 - 8.3e-05 21.8 0.3 0.0049 16.0 0.1 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 CEG38152.1 - 0.00014 22.1 0.3 0.35 11.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 CEG38152.1 - 0.00046 19.8 0.0 0.07 12.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEG38152.1 - 0.0011 18.2 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 CEG38152.1 - 0.0012 18.6 0.3 0.13 11.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 CEG38152.1 - 0.0014 17.9 0.1 0.029 13.6 0.1 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 CEG38152.1 - 0.0036 17.8 0.0 4.5 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CEG38152.1 - 0.0041 16.5 0.8 0.39 10.0 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 CEG38152.1 - 0.005 17.1 0.0 0.52 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 CEG38152.1 - 0.0062 16.6 4.6 0.81 9.7 0.0 3.8 4 0 0 4 4 3 1 Dynamin family cobW PF02492.19 CEG38152.1 - 0.017 14.7 0.8 0.6 9.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CEG38152.1 - 0.018 14.8 0.0 0.3 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CEG38152.1 - 0.024 13.6 0.4 0.31 9.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 CEG38152.1 - 0.034 14.6 0.1 0.93 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEG38152.1 - 0.047 13.9 0.0 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 CEG38152.1 - 0.065 12.0 0.2 0.21 10.3 0.2 1.8 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_11 PF13086.6 CEG38152.1 - 0.069 12.9 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG38152.1 - 0.07 13.2 3.8 5 7.1 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 CEG38152.1 - 0.12 11.5 0.4 3.8 6.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) GPI-anchored PF10342.9 CEG38154.1 - 9.3e-07 29.5 0.0 1.4e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HGTP_anticodon PF03129.20 CEG38154.1 - 0.14 12.3 0.0 0.59 10.3 0.0 1.8 1 1 1 2 2 2 0 Anticodon binding domain HEAT PF02985.22 CEG38155.1 - 8.1e-06 25.7 3.7 0.17 12.2 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Pmp3 PF01679.17 CEG38156.1 - 2.4e-21 75.6 5.6 2.7e-21 75.5 5.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Acetyltransf_13 PF13880.6 CEG38157.1 - 6.4e-21 74.1 0.0 1.6e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CEG38157.1 - 6.6e-16 57.9 0.4 1.2e-15 57.0 0.4 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 CEG38157.1 - 0.0012 19.0 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEG38157.1 - 0.013 15.9 0.0 0.04 14.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Mss51 PF13824.6 CEG38157.1 - 0.25 11.5 1.1 1.5 8.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 AdoHcyase PF05221.17 CEG38158.1 - 2.6e-143 476.6 0.1 2.9e-143 476.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CEG38158.1 - 1.4e-80 269.1 4.8 2.2e-80 268.4 4.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEG38158.1 - 2.5e-10 40.0 0.6 4.3e-10 39.3 0.6 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CEG38158.1 - 7.6e-06 25.6 0.7 1.3e-05 24.8 0.7 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 CEG38158.1 - 0.0024 17.9 0.6 0.0084 16.2 0.6 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CEG38158.1 - 0.0025 17.6 0.2 0.0048 16.6 0.2 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.19 CEG38158.1 - 0.0055 16.0 3.4 0.024 13.9 3.4 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 CEG38158.1 - 0.015 15.7 0.2 0.057 13.9 0.3 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 CEG38158.1 - 0.018 15.3 1.6 0.058 13.7 0.4 2.4 2 1 0 2 2 2 0 TrkA-N domain DUP PF00674.18 CEG38158.1 - 0.028 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 DUP family 3HCDH_N PF02737.18 CEG38158.1 - 0.24 11.3 2.0 1.5 8.7 1.9 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_desaturase PF00487.24 CEG38159.1 - 2e-13 50.7 21.3 3e-13 50.2 21.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.13 CEG38159.1 - 0.033 14.5 1.2 0.033 14.5 1.2 2.5 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily DUF5350 PF17299.2 CEG38159.1 - 0.13 12.8 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5350) Phage_holin_6_1 PF09682.10 CEG38160.1 - 0.021 15.2 0.1 0.044 14.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) ubiquitin PF00240.23 CEG38161.1 - 7.8e-34 115.3 0.3 1.7e-33 114.2 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CEG38161.1 - 4.4e-26 90.8 5.1 1.1e-25 89.5 5.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CEG38161.1 - 1.1e-15 57.2 0.6 1.1e-15 57.2 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEG38161.1 - 1.9e-05 25.0 1.6 0.00025 21.4 0.3 3.0 2 1 1 3 3 3 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEG38161.1 - 0.00059 19.9 0.3 0.0014 18.7 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CEG38161.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CEG38161.1 - 0.013 16.1 0.4 0.02 15.5 0.4 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEG38161.1 - 0.018 15.4 2.3 0.035 14.5 0.1 2.4 1 1 2 3 3 3 0 Ubiquitin-like domain Syncollin PF15138.6 CEG38162.1 - 0.012 15.8 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Syncollin DUF5065 PF16723.5 CEG38163.1 - 0.51 10.4 2.4 1.2 9.2 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) FUSC PF04632.12 CEG38163.1 - 1.1 7.7 3.9 1.7 7.1 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4833 PF16117.5 CEG38164.1 - 7.8e-41 139.3 0.0 9.6e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) CDC45 PF02724.14 CEG38165.1 - 7.2e-125 417.7 0.0 8.1e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein PCMT PF01135.19 CEG38166.1 - 2.1e-54 184.5 0.0 2.8e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CEG38166.1 - 0.00059 20.5 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38166.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEG38166.1 - 0.0048 16.9 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38166.1 - 0.0083 16.8 0.1 0.021 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG38166.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEG38166.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain LRR_8 PF13855.6 CEG38167.1 - 1.1e-36 124.4 34.9 3.6e-11 42.7 0.9 7.9 4 2 3 8 8 8 7 Leucine rich repeat Pkinase_Tyr PF07714.17 CEG38167.1 - 1.7e-27 96.4 1.9 6.9e-22 78.0 1.1 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 CEG38167.1 - 9.2e-25 87.5 5.0 7.9e-24 84.4 1.5 3.7 3 1 0 3 3 3 1 Protein kinase domain LRR_4 PF12799.7 CEG38167.1 - 1.6e-13 50.6 47.3 0.01 16.2 1.6 8.2 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CEG38167.1 - 8.2e-12 45.2 12.0 6.8e-05 22.8 0.2 4.1 2 2 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CEG38167.1 - 1e-05 25.4 27.5 7.2 7.6 0.1 11.0 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 CEG38167.1 - 9.5e-05 22.0 15.0 0.0021 17.6 1.5 3.6 2 1 1 3 3 3 2 Leucine-rich repeat APH PF01636.23 CEG38167.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ephrin_rec_like PF07699.13 CEG38167.1 - 3.7 7.4 6.2 3.5 7.5 2.3 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like Pterin_4a PF01329.19 CEG38169.1 - 2.1e-28 98.3 0.1 2.4e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RNA_pol_L_2 PF13656.6 CEG38170.1 - 3.8e-29 100.3 0.0 4.6e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEG38170.1 - 2.9e-11 42.6 0.0 4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PX PF00787.24 CEG38171.1 - 3.2e-13 49.7 0.0 6.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 PX domain Lipase_3 PF01764.25 CEG38172.1 - 6.9e-12 45.4 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEG38172.1 - 0.046 14.3 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3270 PF11674.8 CEG38172.1 - 0.091 12.9 3.8 0.66 10.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) Hydrolase_4 PF12146.8 CEG38172.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 CEG38173.1 - 8.6e-12 45.4 11.1 0.024 15.5 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.6 CEG38173.1 - 0.0003 20.4 0.4 0.022 14.3 0.2 2.3 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 CEG38173.1 - 0.043 14.1 0.1 9.6 6.6 0.0 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CD45 PF12567.8 CEG38176.1 - 0.074 13.0 0.3 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Leukocyte receptor CD45 Tubulin-binding PF00418.19 CEG38176.1 - 0.12 12.4 0.1 0.53 10.3 0.1 2.2 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat SLC35F PF06027.12 CEG38177.1 - 1.9e-09 37.5 4.6 1.9e-09 37.5 4.6 1.9 2 1 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 CEG38177.1 - 2.6e-07 30.9 21.1 4.9e-06 26.8 6.9 3.6 2 2 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CEG38177.1 - 6.5e-07 28.9 6.8 1e-06 28.3 6.8 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 CEG38177.1 - 2.5e-05 23.6 9.0 3.6e-05 23.1 9.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 CEG38177.1 - 0.00033 19.7 5.5 0.00033 19.7 5.5 2.1 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 CEG38177.1 - 0.00058 19.3 8.4 0.0015 18.0 8.4 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Methyltransf_8 PF05148.15 CEG38178.1 - 5.3e-77 258.6 0.0 6.8e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CEG38178.1 - 5.5e-06 26.9 0.1 0.00012 22.7 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38178.1 - 0.00034 21.2 0.0 0.045 14.5 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_29 PF03141.16 CEG38178.1 - 0.045 12.3 0.2 0.23 10.0 0.0 2.1 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 CEG38178.1 - 0.047 13.5 0.0 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain MPS2 PF17060.5 CEG38178.1 - 0.067 12.5 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Methyltransf_12 PF08242.12 CEG38178.1 - 0.075 13.8 0.3 7.5 7.4 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 CEG38179.1 - 6.3e-34 117.5 0.0 8e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38179.1 - 9.4e-19 67.7 0.0 3.5e-08 33.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 CEG38179.1 - 0.0054 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG38179.1 - 0.009 15.4 0.0 2 7.7 0.0 2.9 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CEG38179.1 - 0.014 15.0 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEG38179.1 - 0.022 14.7 0.5 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5315 PF17242.2 CEG38179.1 - 0.8 9.6 3.2 31 4.5 0.9 2.8 2 1 1 3 3 3 0 Disordered region of unknown function (DUF5315) Oxidored_q2 PF00420.24 CEG38181.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Eapp_C PF10238.9 CEG38182.1 - 6e-41 140.0 8.1 1.1e-40 139.2 8.1 1.4 1 0 0 1 1 1 1 E2F-associated phosphoprotein PH PF00169.29 CEG38183.1 - 8.4e-14 52.0 0.3 2.2e-07 31.3 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CEG38183.1 - 5.9e-08 33.1 2.2 0.0039 17.6 0.2 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CEG38183.1 - 0.002 18.4 0.2 1.8 8.9 0.1 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_12 PF16457.5 CEG38183.1 - 0.0027 18.3 1.6 1.3 9.5 0.1 3.0 1 1 1 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 CEG38183.1 - 0.025 14.4 0.3 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 CEG38183.1 - 0.062 13.1 0.4 3.7 7.3 0.1 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain MMR1 PF08505.10 CEG38183.1 - 0.068 13.5 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pkinase_Tyr PF07714.17 CEG38184.1 - 3.7e-41 141.1 0.0 5.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG38184.1 - 6.4e-41 140.5 0.0 1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC2_membrane_2 PF12679.7 CEG38184.1 - 0.012 15.0 8.5 0.024 13.9 8.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein IFT43 PF15305.6 CEG38184.1 - 0.057 13.6 0.1 9.1 6.5 0.0 2.6 3 0 0 3 3 3 0 Intraflagellar transport protein 43 Adap_comp_sub PF00928.21 CEG38188.1 - 5.1e-83 278.5 0.0 6.1e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEG38188.1 - 1.1e-05 25.4 0.4 1.9e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CEG38188.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PALP PF00291.25 CEG38189.1 - 2.2e-48 165.1 1.5 3e-48 164.7 1.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Vma12 PF11712.8 CEG38190.1 - 0.44 10.6 5.3 3.2 7.8 0.5 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DHDPS PF00701.22 CEG38195.1 - 2e-88 295.9 0.1 2.3e-88 295.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.14 CEG38195.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase PEP_mutase PF13714.6 CEG38195.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase rve PF00665.26 CEG38196.1 - 1.4e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain Cys_Met_Meta_PP PF01053.20 CEG38197.1 - 3.3e-142 473.6 0.1 2.3e-114 381.9 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEG38197.1 - 1.3e-06 27.9 0.1 2.9e-05 23.4 0.1 2.1 1 1 1 2 2 2 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 CEG38197.1 - 3.1e-05 22.7 0.0 4.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 CEG38197.1 - 0.00058 19.2 0.2 0.0022 17.3 0.2 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEG38197.1 - 0.0016 17.9 0.7 1.3 8.3 0.0 2.9 1 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEG38197.1 - 0.0027 16.7 0.3 0.0067 15.4 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V MHB PF16525.5 CEG38197.1 - 0.024 14.9 0.1 0.13 12.5 0.1 2.1 2 0 0 2 2 2 0 Haemophore, haem-binding Sel1 PF08238.12 CEG38198.1 - 2.5e-05 24.8 1.0 0.66 10.7 0.0 3.4 3 1 0 3 3 3 2 Sel1 repeat Luciferase_N PF05295.11 CEG38198.1 - 0.11 12.5 0.1 0.38 10.8 0.1 1.8 1 1 1 2 2 2 0 Luciferase/LBP N-terminal domain Glyco_hydro_63 PF03200.16 CEG38199.1 - 0.071 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain OMPdecase PF00215.24 CEG38201.1 - 4.6e-29 101.6 0.0 1e-28 100.5 0.0 1.6 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 CEG38201.1 - 1e-18 67.3 0.1 2.1e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Img2 PF05046.14 CEG38202.1 - 4.7e-11 42.8 0.0 5.6e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CEG38202.1 - 0.0045 17.5 0.0 0.005 17.3 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor SUI1 ARID PF01388.21 CEG38203.1 - 9.1e-11 42.3 0.0 1.8e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Ras PF00071.22 CEG38204.1 - 1.4e-36 125.6 0.4 2.2e-36 124.9 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CEG38204.1 - 1.6e-27 96.1 0.1 4.9e-27 94.5 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG38204.1 - 1.1e-14 54.2 0.1 2.2e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG38204.1 - 1.6e-06 27.6 0.1 3.2e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG38204.1 - 4.3e-05 23.0 0.0 9.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG38204.1 - 0.00077 19.5 0.5 0.0029 17.7 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEG38204.1 - 0.0038 17.6 0.1 0.014 15.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 CEG38204.1 - 0.0047 16.1 1.0 0.14 11.3 0.0 2.8 1 1 2 3 3 3 1 G-protein alpha subunit AAA PF00004.29 CEG38204.1 - 0.015 15.7 0.0 0.049 14.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CEG38204.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Herpes_BLRF2 PF05812.12 CEG38204.1 - 0.024 14.7 0.3 0.048 13.8 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TniB PF05621.11 CEG38204.1 - 0.028 13.8 0.0 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein GTP_EFTU PF00009.27 CEG38204.1 - 0.028 13.9 2.1 0.059 12.9 0.1 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 CEG38204.1 - 0.11 12.5 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3567 PF12091.8 CEG38204.1 - 0.16 12.1 0.2 0.48 10.6 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3567) Toxin_12 PF07740.12 CEG38207.1 - 0.007 17.0 3.3 0.0093 16.6 3.3 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin NSP10 PF09401.10 CEG38207.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 RNA synthesis protein NSP10 PARP PF00644.20 CEG38208.1 - 9.9e-42 142.7 0.0 1.8e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CEG38208.1 - 9.5e-22 77.6 0.1 1.4e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Herpes_teg_N PF04843.12 CEG38208.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Peptidase_M48_N PF16491.5 CEG38209.1 - 3.2e-74 248.8 1.3 6e-74 247.9 1.3 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CEG38209.1 - 1.3e-43 149.1 0.0 1.9e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 CEG38209.1 - 0.064 12.4 1.3 0.24 10.6 1.2 1.8 1 1 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 CEG38209.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.6 CEG38209.1 - 0.2 11.4 0.9 0.41 10.4 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) CENP-C_C PF11699.8 CEG38210.1 - 2.2e-06 27.8 0.0 0.0037 17.4 0.0 2.8 2 1 0 2 2 2 2 Mif2/CENP-C like Cupin_1 PF00190.22 CEG38210.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin PAP_central PF04928.17 CEG38211.1 - 7e-06 25.2 0.8 2.2e-05 23.6 0.2 2.0 2 0 0 2 2 2 1 Poly(A) polymerase central domain MbeB_N PF04837.12 CEG38213.1 - 0.11 12.8 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 MbeB-like, N-term conserved region RVT_1 PF00078.27 CEG38215.1 - 7.1e-21 74.7 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHB_depo_C PF06850.11 CEG38218.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Retrotrans_gag PF03732.17 CEG38219.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4939 PF16297.5 CEG38219.1 - 0.061 13.2 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) CorA PF01544.18 CEG38220.1 - 3.8e-05 23.2 8.8 0.00047 19.6 8.8 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Adap_comp_sub PF00928.21 CEG38221.1 - 4.6e-67 226.2 0.2 5.5e-67 225.9 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEG38221.1 - 3.1e-07 30.4 0.7 4.6e-07 29.9 0.1 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DWNN PF08783.11 CEG38222.1 - 1.1e-26 92.8 0.3 2.9e-26 91.5 0.3 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CEG38222.1 - 1.1e-07 31.5 6.9 1.1e-07 31.5 6.9 1.8 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 CEG38222.1 - 0.0001 22.4 0.1 0.00028 21.0 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-CCHC PF00098.23 CEG38222.1 - 0.00059 19.8 2.2 0.00059 19.8 2.2 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 CEG38222.1 - 0.0022 17.8 12.1 0.0046 16.8 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 CEG38222.1 - 0.0039 16.9 0.7 0.013 15.2 0.7 1.9 1 0 0 1 1 1 1 Cd27 binding protein (Siva) zf-C3HC4_3 PF13920.6 CEG38222.1 - 0.0063 16.3 11.3 0.0063 16.3 11.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG38222.1 - 0.029 14.7 10.9 0.059 13.7 10.9 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 CEG38222.1 - 0.49 10.3 11.8 2 8.3 11.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG38222.1 - 0.5 10.3 11.8 1 9.3 11.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG38222.1 - 3.8 7.6 15.7 0.13 12.3 9.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 CEG38222.1 - 8.4 6.3 9.1 18 5.2 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CHCH PF06747.13 CEG38224.1 - 5.2e-09 36.0 6.3 8.2e-09 35.4 6.3 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 CEG38224.1 - 0.073 13.4 3.0 0.096 13.0 3.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 CEG38224.1 - 0.079 13.2 3.7 0.1 12.8 3.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CEG38224.1 - 0.091 12.8 5.7 0.094 12.7 4.8 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Na_K-ATPase PF00287.18 CEG38224.1 - 0.47 9.6 5.6 0.55 9.4 5.6 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain GTP_EFTU PF00009.27 CEG38225.1 - 5.6e-64 215.3 0.4 8.6e-64 214.7 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CEG38225.1 - 1.6e-29 102.1 0.0 1.1e-28 99.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CEG38225.1 - 1.8e-20 72.8 0.0 6e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CEG38225.1 - 1e-14 54.4 0.1 2.4e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEG38225.1 - 7.1e-12 45.6 0.1 2.3e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG38225.1 - 0.00033 20.7 0.1 0.0017 18.4 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase LamB_YcsF PF03746.16 CEG38226.1 - 0.0089 15.7 0.2 0.0098 15.6 0.2 1.0 1 0 0 1 1 1 1 LamB/YcsF family Mannosyl_trans3 PF11051.8 CEG38227.1 - 3.6e-35 121.7 0.2 2.5e-33 115.6 0.2 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 CEG38228.1 - 2.3e-38 132.1 0.0 2.4e-36 125.5 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative THDPS_M PF14789.6 CEG38228.1 - 0.019 15.0 0.1 14 5.9 0.0 3.0 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle SUKH_5 PF14567.6 CEG38228.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall DUF3969 PF13108.6 CEG38228.1 - 0.07 13.2 0.2 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3969) Aminotran_3 PF00202.21 CEG38230.1 - 3.7e-43 147.7 0.0 4.8e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ECH_1 PF00378.20 CEG38231.1 - 1.3e-62 211.4 0.0 1.5e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEG38231.1 - 2.2e-17 63.5 0.0 2.6e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M20 PF01546.28 CEG38232.1 - 2.4e-36 125.4 0.1 3e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 CEG38232.1 - 2.1e-09 37.4 0.0 4.3e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 M20_dimer PF07687.14 CEG38232.1 - 3.4e-09 36.6 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-RING_14 PF17978.1 CEG38233.1 - 0.038 14.4 0.9 0.11 13.0 0.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1244 PF06844.11 CEG38233.1 - 0.056 13.6 2.0 0.86 9.8 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Tli4_N PF18443.1 CEG38233.1 - 0.12 12.8 2.0 0.41 11.0 2.0 1.8 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Spc7 PF08317.11 CEG38237.1 - 7.7e-05 21.7 13.7 7.7e-05 21.7 13.7 6.1 4 2 2 6 6 6 3 Spc7 kinetochore protein HsbA PF12296.8 CEG38237.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.2 3 1 0 3 3 3 0 Hydrophobic surface binding protein A PKcGMP_CC PF16808.5 CEG38237.1 - 9 6.2 26.2 0.22 11.4 1.3 5.6 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 CEG38237.1 - 9.8 6.2 9.5 31 4.6 0.9 4.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1084 PF06454.11 CEG38238.1 - 0.00012 21.6 7.6 0.0045 16.4 7.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Methyltransf_25 PF13649.6 CEG38239.1 - 5.6e-11 43.0 0.0 1.3e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38239.1 - 1.6e-10 41.0 0.0 4.6e-10 39.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38239.1 - 1.9e-09 38.0 0.0 3.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG38239.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CEG38239.1 - 0.0022 17.7 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 CEG38239.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Asp PF00026.23 CEG38240.1 - 4.8e-39 134.6 0.0 2.9e-38 132.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG38240.1 - 3.3e-14 53.5 0.1 4.7e-11 43.2 0.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG38240.1 - 4e-05 23.5 0.7 0.00018 21.3 0.7 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Rhv PF00073.20 CEG38240.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 picornavirus capsid protein PPP5 PF08321.12 CEG38243.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 PPP5 TPR repeat region Sdh5 PF03937.16 CEG38244.1 - 2e-17 62.9 0.3 3.2e-17 62.2 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase RVT_2 PF07727.14 CEG38245.1 - 9.9e-22 77.8 0.0 1.1e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 CEG38247.1 - 5.4e-21 73.8 23.4 1.6e-06 28.2 0.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG38247.1 - 6.6e-16 57.6 20.9 0.00064 20.3 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEG38247.1 - 1.8e-10 40.7 30.0 8.9e-07 29.1 2.1 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 CEG38247.1 - 0.00045 19.9 15.5 0.1 12.4 0.3 4.0 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CEG38247.1 - 0.00056 19.8 0.3 0.00056 19.8 0.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEG38247.1 - 0.007 16.6 9.2 0.089 13.1 1.8 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEG38247.1 - 0.015 15.9 10.5 0.58 10.8 0.2 3.7 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CEG38247.1 - 0.02 15.2 6.4 0.37 11.1 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CEG38247.1 - 0.042 13.6 0.2 0.042 13.6 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain GAGA PF09237.11 CEG38247.1 - 0.043 13.6 0.7 0.043 13.6 0.7 2.9 2 1 1 3 3 3 0 GAGA factor zf-DNA_Pol PF08996.10 CEG38247.1 - 1.3 8.8 6.5 3.1 7.5 1.8 2.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-CCHC PF00098.23 CEG38249.1 - 2.6e-06 27.2 2.2 3.9e-06 26.7 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEG38249.1 - 0.046 13.5 1.0 0.046 13.5 1.0 1.7 2 0 0 2 2 2 0 Zinc knuckle Ribophorin_II PF05817.14 CEG38250.1 - 7.9e-65 219.6 2.7 1.1e-64 219.2 2.7 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF3324 PF11797.8 CEG38250.1 - 0.032 14.2 0.2 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) UXS1_N PF11803.8 CEG38250.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal CHB_HEX_C_1 PF13290.6 CEG38250.1 - 0.098 12.7 0.9 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Cation_ATPase PF13246.6 CEG38251.1 - 0.061 13.4 0.5 2.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Cation transport ATPase (P-type) zf-RING_2 PF13639.6 CEG38252.1 - 5.9e-12 45.7 10.7 1.2e-11 44.7 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEG38252.1 - 4.3e-09 36.0 2.1 4.3e-09 36.0 2.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEG38252.1 - 4.7e-07 29.6 10.2 4.7e-07 29.6 10.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG38252.1 - 3.3e-06 27.0 1.2 3.3e-06 27.0 1.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG38252.1 - 1.4e-05 24.8 9.9 3.6e-05 23.5 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG38252.1 - 2.6e-05 24.1 10.2 4.6e-05 23.3 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEG38252.1 - 4.4e-05 23.7 13.5 0.00043 20.5 13.5 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEG38252.1 - 0.0013 18.5 9.4 0.0025 17.7 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG38252.1 - 0.077 12.9 10.4 0.15 11.9 10.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CEG38252.1 - 0.22 11.4 3.9 0.48 10.3 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 CEG38252.1 - 0.23 11.5 7.8 0.72 10.0 7.8 1.9 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CEG38252.1 - 0.36 10.8 8.9 1.6 8.8 8.9 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.7 CEG38252.1 - 1.3 9.2 8.9 2.9 8.1 8.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CEG38252.1 - 1.3 9.1 8.9 4.6 7.4 8.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CEG38252.1 - 2.8 7.7 10.5 2.9 7.6 8.7 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type UDPGP PF01704.18 CEG38253.1 - 4.3e-170 565.8 0.4 5e-170 565.6 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF2065 PF09838.9 CEG38254.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) HA1 PF18239.1 CEG38258.1 - 0.084 12.7 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin I DUF4756 PF15948.5 CEG38258.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) gag-asp_proteas PF13975.6 CEG38259.1 - 0.007 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEG38259.1 - 0.0086 15.9 0.0 0.062 13.1 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEG38259.1 - 0.01 16.4 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RNA_pol_Rpb1_4 PF05000.17 CEG38259.1 - 0.052 13.5 0.1 0.21 11.5 0.0 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 4 RVT_1 PF00078.27 CEG38260.1 - 0.00035 20.2 0.0 0.00045 19.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myosin_head PF00063.21 CEG38263.1 - 2.9e-219 729.7 0.7 2.9e-219 729.7 0.7 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CEG38263.1 - 2.6e-09 36.1 28.8 0.15 11.9 0.3 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_16 PF13191.6 CEG38263.1 - 0.013 15.9 0.0 0.076 13.4 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain Myosin_N PF02736.19 CEG38263.1 - 0.036 13.9 0.3 0.093 12.6 0.3 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CEG38263.1 - 0.06 13.6 0.0 0.38 11.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_4 PF02056.16 CEG38263.1 - 0.09 12.3 1.1 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Lzipper-MIP1 PF14389.6 CEG38263.1 - 0.88 9.9 16.8 0.27 11.6 5.0 3.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_1 PF00170.21 CEG38263.1 - 3.1 8.0 20.0 0.85 9.8 0.2 4.4 4 0 0 4 4 4 0 bZIP transcription factor CactinC_cactus PF09732.9 CEG38264.1 - 4.1e-59 198.0 9.5 7.3e-59 197.2 9.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CEG38264.1 - 2.4e-57 193.9 9.2 2.4e-57 193.9 9.2 2.1 2 0 0 2 2 2 1 Conserved mid region of cactin GCS PF03074.16 CEG38265.1 - 3.5e-141 470.8 0.0 5.1e-119 397.9 0.0 2.1 1 1 0 2 2 2 2 Glutamate-cysteine ligase AAA_16 PF13191.6 CEG38265.1 - 0.094 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Bactofilin PF04519.13 CEG38266.1 - 6.7e-19 68.0 3.2 9.1e-19 67.6 3.2 1.2 1 0 0 1 1 1 1 Polymer-forming cytoskeletal TRAM PF01938.20 CEG38266.1 - 0.39 10.7 4.4 5.2 7.1 1.5 2.8 1 1 1 2 2 2 0 TRAM domain WBS_methylT PF12589.8 CEG38267.1 - 9.3e-23 80.8 6.7 9.3e-23 80.8 6.7 1.6 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CEG38267.1 - 4.8e-12 46.4 0.0 1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38267.1 - 8.7e-12 45.6 0.0 1.9e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG38267.1 - 3.5e-05 23.7 0.0 8.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG38267.1 - 5.9e-05 22.5 0.0 0.00019 20.9 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CEG38267.1 - 0.00011 22.9 0.0 0.0003 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38267.1 - 0.00026 20.8 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 CEG38267.1 - 0.0028 17.4 0.1 0.019 14.7 0.0 2.1 2 1 0 2 2 2 1 DNA methylase PrmA PF06325.13 CEG38267.1 - 0.0033 16.9 0.1 0.011 15.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CEG38267.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CEG38267.1 - 0.02 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CEG38267.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CEG38267.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 CEG38267.1 - 0.033 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 CEG38267.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 CEG38268.1 - 2.2e-72 243.6 0.0 2.5e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38268.1 - 8e-30 104.0 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG38268.1 - 1.5e-06 27.8 0.0 0.00062 19.2 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CEG38268.1 - 0.0094 14.9 0.0 0.025 13.6 0.0 1.6 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 CEG38268.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.25 CEG38269.1 - 1.2e-64 218.1 0.0 1.7e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG38269.1 - 5.3e-50 168.8 0.1 8.3e-50 168.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEG38269.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.9 3 0 0 3 3 3 1 Tubulin domain Glyco_hydro_30 PF02055.16 CEG38270.1 - 7.5e-85 285.0 0.3 1.1e-84 284.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 CEG38270.1 - 9.7e-15 54.9 9.2 1e-10 42.0 2.3 2.6 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 CEG38270.1 - 5.7e-09 36.1 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 CEG38270.1 - 8.3e-07 28.5 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 RicinB_lectin_2 PF14200.6 CEG38270.1 - 0.00039 21.1 1.8 0.0045 17.7 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 CEG38270.1 - 0.0018 17.9 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Tubulin PF00091.25 CEG38277.1 - 4e-68 229.5 0.1 6.9e-68 228.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG38277.1 - 1.4e-48 164.3 0.0 3.3e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEG38277.1 - 4.3e-05 23.8 0.0 0.00012 22.4 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CEG38277.1 - 0.0097 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin like DUF1688 PF07958.11 CEG38278.1 - 5.9e-157 522.7 0.0 7.2e-157 522.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) BT1 PF03092.16 CEG38278.1 - 1.6e-17 63.0 12.4 3.2e-09 35.6 0.1 3.3 3 0 0 3 3 3 3 BT1 family DUF4271 PF14093.6 CEG38278.1 - 0.042 13.8 0.9 0.1 12.5 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) LRR_9 PF14580.6 CEG38279.1 - 7e-14 51.7 1.5 1.4e-13 50.8 1.5 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEG38279.1 - 5.9e-09 36.1 11.4 0.00048 20.5 2.9 3.5 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG38279.1 - 2.7e-05 23.8 6.0 2.7e-05 23.8 6.0 2.6 3 0 0 3 3 3 1 Leucine rich repeat PIH1_CS PF18201.1 CEG38279.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain LRR_1 PF00560.33 CEG38279.1 - 5.8 7.9 7.7 29 5.8 0.2 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat DPM2 PF07297.12 CEG38280.1 - 1.6e-28 98.8 3.0 1.9e-28 98.6 3.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CEG38280.1 - 0.0042 17.0 1.6 0.0047 16.8 1.6 1.1 1 0 0 1 1 1 1 PIG-P Tom22 PF04281.13 CEG38281.1 - 2.2e-06 27.5 0.1 3.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Ly49 PF08391.10 CEG38281.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Endonuc-dimeris PF09124.10 CEG38281.1 - 0.15 12.2 1.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation HATPase_c_3 PF13589.6 CEG38282.1 - 4.4e-09 36.3 0.1 8.2e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEG38282.1 - 9.5e-07 29.3 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Topo-VIb_trans PF09239.11 CEG38282.1 - 0.0033 17.3 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer MCPVI PF02993.14 CEG38282.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI MIF4G PF02854.19 CEG38283.1 - 0.0048 16.6 0.3 0.0075 15.9 0.3 1.3 1 0 0 1 1 1 1 MIF4G domain Rif1_N PF12231.8 CEG38286.1 - 1.8e-20 73.3 4.2 1.8e-20 73.3 4.2 1.6 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Arginosuc_synth PF00764.19 CEG38287.1 - 3.1e-134 448.1 0.0 3.8e-134 447.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CEG38287.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CEG38287.1 - 0.049 12.4 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ATP_bind_3 PF01171.20 CEG38287.1 - 0.087 12.6 0.1 2.5 7.8 0.0 2.5 1 1 1 2 2 2 0 PP-loop family ADH_N PF08240.12 CEG38288.1 - 2.2e-25 88.6 1.7 4.8e-25 87.5 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEG38288.1 - 1.2e-23 83.5 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEG38288.1 - 0.0034 16.7 0.1 0.0072 15.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CEG38288.1 - 0.017 16.2 0.0 0.038 15.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 CEG38288.1 - 0.018 14.6 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CEG38288.1 - 0.031 13.6 0.2 0.064 12.5 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 CEG38288.1 - 0.032 13.7 0.1 0.3 10.5 0.1 2.2 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus RET_CLD3 PF17812.1 CEG38288.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 RET Cadherin like domain 3 TrkA_N PF02254.18 CEG38288.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RNA_pol_Rpb1_5 PF04998.17 CEG38290.1 - 1.4e-89 300.1 0.1 4e-89 298.6 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CEG38290.1 - 2.5e-84 283.3 0.0 4.9e-84 282.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CEG38290.1 - 9.1e-76 253.7 0.0 2e-75 252.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEG38290.1 - 6.8e-39 133.3 0.0 3.1e-38 131.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CEG38290.1 - 2.1e-28 98.4 0.0 4.7e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 CEG38290.1 - 0.074 12.7 0.5 0.19 11.4 0.5 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Rpr2 PF04032.16 CEG38290.1 - 0.36 11.1 3.1 0.38 11.1 0.6 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_7 PF02591.15 CEG38290.1 - 2.2 8.5 4.7 3.4 7.9 0.1 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain SPT16 PF08644.11 CEG38291.1 - 6.8e-54 182.1 0.2 6.8e-54 182.1 0.2 2.4 2 0 0 2 2 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CEG38291.1 - 2e-45 154.5 0.1 8.3e-45 152.5 0.1 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CEG38291.1 - 1.6e-31 109.6 0.0 3.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_4 PF13637.6 CEG38291.1 - 5.7e-17 61.9 0.1 1.9e-13 50.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Rtt106 PF08512.12 CEG38291.1 - 9.9e-15 54.7 0.5 2.7e-14 53.4 0.5 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Ank PF00023.30 CEG38291.1 - 9.4e-14 51.2 0.4 2.2e-05 24.7 0.2 4.2 4 0 0 4 4 3 2 Ankyrin repeat Ank_2 PF12796.7 CEG38291.1 - 1.3e-13 51.3 0.0 3.6e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG38291.1 - 1.7e-13 50.5 0.1 3.7e-06 27.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) fn3 PF00041.21 CEG38291.1 - 4.1e-11 43.1 0.1 7.9e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain NARG2_C PF10505.9 CEG38291.1 - 4.4e-10 39.4 0.0 9.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Ank_3 PF13606.6 CEG38291.1 - 2.1e-08 33.7 0.0 0.007 16.8 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat EF-hand_1 PF00036.32 CEG38291.1 - 7e-07 28.4 0.2 0.0005 19.4 0.2 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEG38291.1 - 3.6e-06 26.5 0.4 0.02 14.8 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CEG38291.1 - 4.3e-06 27.1 0.1 2.2e-05 24.8 0.1 2.4 1 0 0 1 1 1 1 EF-hand domain pair Pur_ac_phosph_N PF16656.5 CEG38291.1 - 0.0015 19.0 1.1 0.0047 17.5 0.1 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain EF-hand_5 PF13202.6 CEG38291.1 - 0.0023 17.3 3.4 0.036 13.6 0.2 3.0 3 0 0 3 3 2 1 EF hand EF-hand_8 PF13833.6 CEG38291.1 - 0.37 10.7 5.1 0.097 12.5 0.1 2.5 2 1 1 3 3 2 0 EF-hand domain pair Solute_trans_a PF03619.16 CEG38292.1 - 5.4e-78 262.2 19.4 6.9e-78 261.8 19.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GST_C_2 PF13410.6 CEG38292.1 - 0.33 11.0 1.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PDZ PF00595.24 CEG38293.1 - 1.5e-05 25.3 0.0 5.6 7.4 0.0 5.0 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 CEG38293.1 - 0.00014 21.6 0.0 0.22 11.4 0.0 3.8 4 0 0 4 4 4 1 PDZ domain DUF4200 PF13863.6 CEG38294.1 - 1.2e-33 116.0 24.5 1.2e-33 116.0 24.5 5.3 3 2 3 6 6 6 1 Domain of unknown function (DUF4200) YvrJ PF12841.7 CEG38294.1 - 0.13 11.8 1.5 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family DUF948 PF06103.11 CEG38294.1 - 0.19 12.0 4.9 2.2 8.6 1.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ETC_C1_NDUFA5 PF04716.14 CEG38294.1 - 0.47 10.3 8.4 9.3 6.1 0.1 4.3 4 0 0 4 4 4 0 ETC complex I subunit conserved region NPV_P10 PF05531.12 CEG38294.1 - 0.65 10.5 9.5 0.13 12.8 0.7 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5403 PF17395.2 CEG38294.1 - 0.67 10.3 3.0 0.6 10.4 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5403) Bacillus_HBL PF05791.11 CEG38294.1 - 0.88 9.4 21.3 1.5 8.6 5.7 3.2 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) V-SNARE_C PF12352.8 CEG38295.1 - 0.007 16.6 11.3 0.015 15.6 1.4 3.1 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus zf-C2H2_4 PF13894.6 CEG38295.1 - 0.017 15.9 0.1 0.043 14.7 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG38295.1 - 0.019 15.4 0.2 0.041 14.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 CEG38295.1 - 0.026 14.9 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CEG38295.1 - 0.026 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 CEG38295.1 - 0.045 13.4 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain HrpB7 PF09486.10 CEG38295.1 - 0.047 14.1 0.1 0.047 14.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-C2H2_3rep PF18868.1 CEG38295.1 - 0.048 14.3 0.2 0.048 14.3 0.2 2.0 3 0 0 3 3 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CEG38295.1 - 0.078 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEG38295.1 - 0.097 13.3 4.9 4.8 7.9 0.1 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain Syntaxin-6_N PF09177.11 CEG38295.1 - 0.75 10.4 8.2 0.13 12.8 1.8 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HAP1_N PF04849.13 CEG38295.1 - 2.2 7.4 11.4 0.2 10.9 6.1 1.7 1 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 CEG38295.1 - 2.8 8.0 6.6 1 9.4 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CEG38295.1 - 4.1 7.6 8.0 0.62 10.2 2.5 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CEG38295.1 - 5.6 7.5 10.0 3 8.4 3.6 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CEG38295.1 - 6.2 5.6 11.2 0.23 10.3 4.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein WW PF00397.26 CEG38298.1 - 9.2e-13 48.0 6.7 7.3e-09 35.6 0.7 2.5 2 0 0 2 2 2 2 WW domain HSF_DNA-bind PF00447.17 CEG38298.1 - 0.0033 18.0 0.1 0.013 16.1 0.1 2.1 1 1 0 1 1 1 1 HSF-type DNA-binding Glyco_hyd_101C PF17451.2 CEG38298.1 - 1.2 9.4 9.2 4 7.7 1.7 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain zf-CHY PF05495.12 CEG38299.1 - 1.6e-11 44.5 17.3 2.1e-11 44.1 11.7 2.5 2 0 0 2 2 2 1 CHY zinc finger gag_pre-integrs PF13976.6 CEG38299.1 - 5.1e-11 42.3 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Rubis-subs-bind PF09273.11 CEG38301.1 - 3.5e-22 79.5 2.5 4.7e-22 79.1 1.2 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 CEG38301.1 - 5.9e-07 30.0 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 SET domain SET PF00856.28 CEG38302.1 - 1.3e-10 42.0 0.1 1.4e-10 41.8 0.1 1.2 1 0 0 1 1 1 1 SET domain CWC25 PF12542.8 CEG38303.1 - 3.2e-19 69.7 0.5 3.2e-19 69.7 0.5 5.1 5 2 0 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.9 CEG38303.1 - 6.9e-14 51.8 8.6 6.9e-14 51.8 8.6 5.2 4 2 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR UQ_con PF00179.26 CEG38304.1 - 3.1e-39 133.8 0.0 3.8e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG38304.1 - 0.0093 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain EAF PF09816.9 CEG38305.1 - 5.9e-13 49.1 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor BOF PF04076.13 CEG38305.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein AT_hook PF02178.19 CEG38305.1 - 2.1 8.5 9.5 5 7.3 2.2 2.6 2 0 0 2 2 2 0 AT hook motif FTHFS PF01268.19 CEG38307.1 - 4.3e-251 834.0 0.0 5.3e-251 833.7 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Med31 PF05669.12 CEG38307.1 - 2.2e-35 120.5 7.0 3.5e-35 119.9 7.0 1.3 1 0 0 1 1 1 1 SOH1 EOS1 PF12326.8 CEG38308.1 - 1.4 8.8 8.8 2.2 8.2 8.8 1.5 1 1 0 1 1 1 0 N-glycosylation protein DUF1764 PF08576.10 CEG38308.1 - 2 9.4 8.2 2.7 8.9 7.5 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) OSCP PF00213.18 CEG38313.1 - 0.058 13.5 0.2 0.076 13.1 0.2 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit HTH_WhiA PF02650.14 CEG38313.1 - 0.062 13.6 0.4 0.13 12.6 0.3 1.7 1 1 0 1 1 1 0 WhiA C-terminal HTH domain Tenui_PVC2 PF06656.11 CEG38313.1 - 0.07 11.0 0.2 0.078 10.9 0.2 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein TRAPPC10 PF12584.8 CEG38314.1 - 6.4e-05 22.7 0.0 8.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 CEG38314.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 CEG38314.1 - 0.025 13.3 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi CCT PF06203.14 CEG38316.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 CCT motif RNase_PH PF01138.21 CEG38318.1 - 1e-09 39.0 0.2 1.5e-05 25.5 0.0 2.4 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 TPP_enzyme_N PF02776.18 CEG38318.1 - 0.0011 18.6 0.1 0.0024 17.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain RNase_PH_C PF03725.15 CEG38318.1 - 0.0029 17.6 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TraA PF05513.11 CEG38318.1 - 0.02 15.3 0.3 0.035 14.4 0.2 1.4 1 1 0 1 1 1 0 TraA DnaJ PF00226.31 CEG38319.1 - 2.7e-27 94.6 4.3 4e-27 94.1 4.3 1.3 1 0 0 1 1 1 1 DnaJ domain CDO_I PF05995.12 CEG38320.1 - 7.7e-32 109.9 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CEG38320.1 - 0.00022 20.8 0.1 0.00049 19.6 0.1 1.7 1 1 0 1 1 1 1 PCO_ADO DUF4209 PF13910.6 CEG38321.1 - 0.00039 20.6 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4209) PK PF00224.21 CEG38322.1 - 3.5e-110 368.2 5.1 9.8e-76 254.9 0.0 2.3 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 CEG38322.1 - 7e-23 81.1 1.0 1.5e-22 80.0 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEG38322.1 - 0.00019 20.6 2.0 0.00019 20.6 0.2 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family FokI_N PF02981.15 CEG38322.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Lactamase_B_2 PF12706.7 CEG38323.1 - 5.7e-09 35.8 0.0 5e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CEG38323.1 - 0.0012 18.5 0.0 0.0058 16.3 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease SMC_N PF02463.19 CEG38324.1 - 1.7e-22 80.0 0.0 4.5e-22 78.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG38324.1 - 3.8e-16 60.2 7.9 3.8e-16 60.2 7.9 5.3 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 CEG38324.1 - 0.00018 21.4 1.5 0.083 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEG38324.1 - 0.0029 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CEG38324.1 - 0.02 14.5 1.9 0.032 13.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEG38324.1 - 0.51 10.2 4.1 13 5.7 0.0 3.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CEG38324.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 CEG38324.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ENTH PF01417.20 CEG38325.1 - 4.5e-12 46.1 0.0 8.9e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 CEG38325.1 - 0.00033 19.8 0.0 0.0013 17.8 0.0 1.8 2 0 0 2 2 2 1 ANTH domain VHS PF00790.19 CEG38325.1 - 0.0092 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain DNA_pol_B PF00136.21 CEG38326.1 - 2.7e-89 300.0 0.0 3.9e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEG38326.1 - 3.6e-17 62.5 0.0 8.4e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CEG38326.1 - 0.00014 22.3 6.4 0.00031 21.1 6.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.21 CEG38326.1 - 2.9 8.1 5.7 6.9 6.9 5.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger UreD PF01774.17 CEG38327.1 - 1.6e-62 211.2 0.1 2e-62 210.9 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF5528 PF17666.1 CEG38327.1 - 0.049 13.6 0.2 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5528) Methyltr_RsmB-F PF01189.17 CEG38329.1 - 2.5e-72 242.7 0.1 4.9e-72 241.8 0.1 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CEG38329.1 - 3.4e-08 33.9 0.0 1.1e-07 32.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 CEG38329.1 - 5.6e-06 26.2 0.0 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CEG38329.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 CEG38329.1 - 6.3e-05 23.2 0.1 0.00012 22.2 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 CEG38329.1 - 0.0002 22.0 0.4 0.00069 20.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG38329.1 - 0.003 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CEG38329.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NAD_kinase PF01513.21 CEG38330.1 - 1e-67 228.4 0.0 2.1e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase ENTH PF01417.20 CEG38330.1 - 1e-10 41.8 0.3 2.1e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 ENTH domain DAGK_cat PF00781.24 CEG38330.1 - 0.0017 18.0 0.0 0.0051 16.4 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4719 PF15843.5 CEG38330.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Macoilin PF09726.9 CEG38330.1 - 0.073 11.6 7.1 0.11 11.1 7.1 1.2 1 0 0 1 1 1 0 Macoilin family PPARgamma_N PF12577.8 CEG38331.1 - 0.12 13.0 1.3 2.9 8.6 0.5 2.9 2 0 0 2 2 2 0 PPAR gamma N-terminal region LtuB PF17455.2 CEG38331.1 - 0.17 12.5 6.1 16 6.2 0.3 3.8 2 0 0 2 2 2 0 Late transcription unit B Glutaredoxin PF00462.24 CEG38332.1 - 1.8e-18 66.5 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 CEG38332.1 - 8.9e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEG38332.1 - 1.2e-05 25.6 0.0 1.9e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 CEG38332.1 - 0.0015 18.9 0.1 0.0027 18.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CEG38332.1 - 0.0048 17.3 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CEG38332.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 CEG38332.1 - 0.023 14.9 0.3 0.18 12.0 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 CEG38332.1 - 0.03 14.1 0.1 0.16 11.7 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N PF02798.20 CEG38332.1 - 0.087 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TPP_enzyme_N PF02776.18 CEG38333.1 - 7.4e-56 188.4 0.1 1.7e-55 187.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CEG38333.1 - 9.6e-47 158.6 0.1 7.1e-45 152.5 0.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEG38333.1 - 3.8e-43 146.5 0.5 1.3e-42 144.8 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 CEG38333.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.19 CEG38333.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF5437 PF17505.2 CEG38335.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5437) CcmD PF04995.14 CEG38335.1 - 0.17 12.0 1.4 0.42 10.7 0.2 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) CK_II_beta PF01214.18 CEG38336.1 - 6e-67 225.0 0.0 1.1e-66 224.1 0.0 1.5 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Mak10 PF04112.13 CEG38336.1 - 5.7e-31 107.3 0.2 1.6e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase His_Phos_1 PF00300.22 CEG38337.1 - 9.8e-31 107.0 0.0 3.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Defensin_big PF14862.6 CEG38337.1 - 0.032 14.5 1.0 0.087 13.2 0.5 2.0 2 0 0 2 2 2 0 Big defensin LRR_9 PF14580.6 CEG38338.1 - 1.1e-62 210.6 1.4 1.6e-62 210.1 1.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEG38338.1 - 8.5e-11 41.9 12.7 4.3e-05 23.8 0.5 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) SAP PF02037.27 CEG38338.1 - 1.5e-10 40.6 2.9 3.6e-10 39.4 2.9 1.7 1 0 0 1 1 1 1 SAP domain LRR_8 PF13855.6 CEG38338.1 - 5.8e-07 29.2 12.7 7.4e-06 25.6 4.0 2.7 2 1 1 3 3 3 2 Leucine rich repeat TRAM_LAG1_CLN8 PF03798.16 CEG38339.1 - 4.1e-11 43.0 15.1 6.7e-11 42.3 15.1 1.4 1 0 0 1 1 1 1 TLC domain DUF2456 PF10445.9 CEG38339.1 - 0.14 12.2 7.6 0.046 13.8 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) IRK PF01007.20 CEG38339.1 - 0.2 11.5 3.6 2.2 8.1 0.9 2.5 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Abhydrolase_9_N PF15420.6 CEG38339.1 - 0.25 11.3 4.0 0.14 12.2 1.8 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus bZIP_1 PF00170.21 CEG38341.1 - 1.9e-10 40.6 9.5 1.9e-10 40.6 9.5 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEG38341.1 - 1.5e-07 31.3 11.0 1.5e-07 31.3 11.0 2.5 2 0 0 2 2 2 1 Basic region leucine zipper LTXXQ PF07813.12 CEG38341.1 - 2.2 9.1 14.1 0.43 11.3 3.5 3.0 2 1 0 2 2 2 0 LTXXQ motif family protein bZIP_Maf PF03131.17 CEG38341.1 - 3 8.4 20.4 0.55 10.8 10.8 2.6 2 1 0 2 2 2 0 bZIP Maf transcription factor Exonuc_VII_L PF02601.15 CEG38341.1 - 3.8 7.0 12.1 3.5 7.1 3.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 CEG38341.1 - 5.4 6.0 16.3 0.6 9.1 7.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PA26 PF04636.13 CEG38341.1 - 7 5.4 7.6 1.2 8.0 1.9 1.9 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) R3H PF01424.22 CEG38342.1 - 5.3e-05 23.1 0.1 0.00019 21.4 0.1 1.9 1 0 0 1 1 1 1 R3H domain R3H-assoc PF13902.6 CEG38342.1 - 0.049 14.0 4.3 0.24 11.8 4.3 2.0 1 1 0 1 1 1 0 R3H-associated N-terminal domain DUF640 PF04852.12 CEG38342.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF640) PH PF00169.29 CEG38344.1 - 2.6e-05 24.7 0.0 8.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 PH domain Nucleoporin_C PF03177.14 CEG38345.1 - 0.00012 20.9 7.3 0.077 11.7 5.0 2.3 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Pox_D3 PF04580.13 CEG38345.1 - 0.12 12.0 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirinae D3 protein Chromo PF00385.24 CEG38346.1 - 2.3e-09 37.0 0.1 4.3e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YhhN PF07947.14 CEG38346.1 - 0.0029 17.2 6.3 0.0048 16.5 6.3 1.3 1 0 0 1 1 1 1 YhhN family YoqO PF14037.6 CEG38346.1 - 0.21 12.1 4.7 0.082 13.4 2.0 1.7 2 0 0 2 2 2 0 YoqO-like protein 7TMR-DISM_7TM PF07695.11 CEG38346.1 - 1.7 8.5 6.8 2.6 7.9 6.8 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling MerC PF03203.14 CEG38346.1 - 8.6 6.9 9.7 4.8 7.7 3.0 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein Fucose_iso_N2 PF07882.12 CEG38347.1 - 0.07 12.7 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain BK_channel_a PF03493.18 CEG38348.1 - 3.1e-23 81.8 0.1 1.4e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CEG38348.1 - 8e-13 48.2 12.2 3.9e-12 46.0 11.7 2.4 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CEG38348.1 - 1e-06 28.2 18.8 5.9e-06 25.7 18.8 2.1 1 1 0 1 1 1 1 Ion transport protein Castor_Poll_mid PF06241.12 CEG38348.1 - 7.3e-05 22.7 0.0 0.054 13.5 0.0 3.7 3 0 0 3 3 3 1 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 CEG38348.1 - 0.0014 18.9 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain RXLR_WY PF18634.1 CEG38350.1 - 0.006 16.5 0.5 1.5 8.9 0.1 2.9 2 0 0 2 2 2 2 RXLR phytopathogen effector protein WY-domain Adenylsucc_synt PF00709.21 CEG38354.1 - 1.4e-173 577.6 0.0 1.7e-173 577.3 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1627 PF07789.12 CEG38354.1 - 0.033 13.9 0.6 0.058 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) DUF1033 PF06279.11 CEG38354.1 - 0.2 11.8 0.0 0.49 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) TBCA PF02970.16 CEG38355.1 - 9.5e-25 86.8 4.0 1.1e-24 86.5 4.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF4776 PF16003.5 CEG38355.1 - 0.03 13.3 1.0 0.034 13.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) HMMR_N PF15905.5 CEG38355.1 - 0.045 13.2 3.9 0.049 13.1 3.9 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CotJB PF12652.7 CEG38355.1 - 0.046 13.9 0.3 3.1 8.1 0.0 2.1 2 0 0 2 2 2 0 CotJB protein PEARLI-4 PF05278.12 CEG38355.1 - 0.068 12.8 2.7 0.08 12.5 2.7 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) MMtag PF10159.9 CEG38355.1 - 0.11 12.8 0.6 0.21 11.9 0.6 1.4 1 0 0 1 1 1 0 Multiple myeloma tumor-associated KxDL PF10241.9 CEG38355.1 - 0.13 12.5 1.5 1.6 9.0 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein APG6_N PF17675.1 CEG38356.1 - 0.001 19.6 18.0 0.001 19.6 18.0 5.7 4 1 1 5 5 5 1 Apg6 coiled-coil region HMMR_N PF15905.5 CEG38356.1 - 0.0015 18.1 18.8 0.0015 18.1 18.8 4.4 3 1 2 5 5 5 1 Hyaluronan mediated motility receptor N-terminal LPP PF04728.13 CEG38356.1 - 0.053 13.9 0.3 0.053 13.9 0.3 5.8 5 1 0 5 5 5 0 Lipoprotein leucine-zipper HOOK PF05622.12 CEG38356.1 - 0.49 8.5 62.8 0.022 13.0 52.1 2.2 2 0 0 2 2 2 0 HOOK protein Pex24p PF06398.11 CEG38356.1 - 6.7 5.6 8.2 0.38 9.7 0.8 2.5 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Retrotran_gag_2 PF14223.6 CEG38357.1 - 1.2e-13 50.9 0.4 1.7e-13 50.4 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG38357.1 - 0.00062 19.7 1.6 0.0011 18.9 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CEG38357.1 - 0.05 13.4 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CEG38357.1 - 0.054 13.2 2.2 0.14 11.8 2.2 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CEG38357.1 - 0.066 13.0 0.7 0.23 11.2 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle Amino_oxidase PF01593.24 CEG38359.1 - 5e-19 68.9 0.2 6.8e-18 65.2 0.0 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEG38359.1 - 2.4e-13 50.1 0.1 5.5e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG38359.1 - 8.8e-10 38.7 0.4 3.6e-06 26.8 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEG38359.1 - 4.6e-09 35.9 0.3 3.7e-05 23.1 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEG38359.1 - 1.7e-06 27.7 0.1 3.8e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEG38359.1 - 3.3e-06 26.4 0.3 5.9e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CEG38359.1 - 2.1e-05 24.5 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 CEG38359.1 - 6.8e-05 21.7 1.0 0.013 14.2 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 CEG38359.1 - 0.00021 20.5 0.3 0.0049 16.0 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A MCRA PF06100.11 CEG38359.1 - 0.00045 19.2 0.2 0.00068 18.6 0.2 1.2 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 CEG38359.1 - 0.0011 18.3 0.4 0.0016 17.7 0.4 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CEG38359.1 - 0.0021 17.4 0.4 0.26 10.5 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEG38359.1 - 0.0076 15.3 5.4 0.67 8.9 0.2 3.1 2 1 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 CEG38359.1 - 0.044 14.4 2.3 0.23 12.0 0.8 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEG38359.1 - 0.068 12.4 0.8 0.15 11.3 0.8 1.5 1 0 0 1 1 1 0 FAD binding domain RNA_pol_L_2 PF13656.6 CEG38360.1 - 2.3e-25 88.1 0.0 2.9e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEG38360.1 - 7e-08 31.8 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.18 CEG38360.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RabGAP-TBC PF00566.18 CEG38363.1 - 4.3e-44 150.7 0.1 8.8e-44 149.7 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-HIT PF04438.16 CEG38363.1 - 1.7e-08 34.2 15.0 3.7e-08 33.1 15.0 1.6 1 0 0 1 1 1 1 HIT zinc finger CH PF00307.31 CEG38363.1 - 9e-08 32.3 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain NPP1 PF05630.11 CEG38366.1 - 3.6e-49 167.5 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) EBP PF05241.12 CEG38367.1 - 0.12 11.8 0.1 0.15 11.5 0.1 1.4 1 1 0 1 1 1 0 Emopamil binding protein NPP1 PF05630.11 CEG38368.1 - 4.3e-50 170.6 0.6 5.2e-50 170.3 0.6 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Ribosomal_L22 PF00237.19 CEG38369.1 - 0.17 12.1 0.1 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e IQ PF00612.27 CEG38375.1 - 2.3 8.3 12.9 0.84 9.6 3.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif TPR_1 PF00515.28 CEG38376.1 - 2.5e-21 74.5 19.3 0.00018 21.2 0.2 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG38376.1 - 5.9e-17 60.3 18.6 0.0015 18.5 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38376.1 - 2.5e-11 43.1 7.1 8.1e-05 22.2 0.1 5.4 3 1 2 5 5 5 3 TPR repeat TPR_8 PF13181.6 CEG38376.1 - 1.9e-10 40.1 11.0 0.13 12.5 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG38376.1 - 1.9e-07 31.3 9.8 0.00017 21.8 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG38376.1 - 5.3e-06 26.5 2.4 0.046 13.9 1.2 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG38376.1 - 7.6e-05 23.3 9.2 0.28 11.9 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG38376.1 - 0.00016 21.8 11.4 0.26 11.8 0.1 5.0 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG38376.1 - 0.00053 20.4 3.9 0.88 10.1 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG38376.1 - 0.00079 19.3 3.8 5.7 7.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat YqaH PF17448.2 CEG38376.1 - 0.0013 19.0 0.1 0.0092 16.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized YqaH-like Fis1_TPR_C PF14853.6 CEG38376.1 - 0.0025 17.8 2.6 1.3 9.2 0.2 4.2 4 1 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CEG38376.1 - 0.055 14.3 10.9 5.5 8.1 1.7 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG38376.1 - 0.072 13.8 6.7 5.3 7.9 0.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CEG38376.1 - 0.12 12.5 12.3 7.8 6.7 0.1 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 CEG38376.1 - 0.23 10.8 6.8 0.099 12.0 0.5 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Mob_synth_C PF06463.13 CEG38378.1 - 1.2e-35 122.2 0.0 2.4e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 CEG38378.1 - 1.4e-27 97.2 0.0 2.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 CEG38378.1 - 1.6e-09 38.2 0.0 3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 CEG38378.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Asp_protease PF09668.10 CEG38379.1 - 0.093 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Aspartyl protease COPIIcoated_ERV PF07970.12 CEG38380.1 - 9.3e-69 231.6 0.6 1.6e-68 230.8 0.6 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter CEP44 PF15007.6 CEG38380.1 - 3.6e-35 120.9 0.3 7.9e-35 119.8 0.3 1.6 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 ERGIC_N PF13850.6 CEG38380.1 - 2.3e-24 85.5 0.1 6.7e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Filo_VP35 PF02097.15 CEG38380.1 - 0.034 13.2 0.4 0.1 11.6 0.2 1.9 1 1 0 1 1 1 0 Filoviridae VP35 F-box-like PF12937.7 CEG38381.1 - 0.037 13.9 0.6 0.11 12.3 0.5 1.9 2 1 0 2 2 2 0 F-box-like TauE PF01925.19 CEG38382.1 - 0.12 12.0 1.3 0.21 11.2 0.1 1.9 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE Peptidase_S9 PF00326.21 CEG38383.1 - 4.8e-07 29.5 0.2 0.00048 19.7 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEG38383.1 - 9.4e-06 25.1 0.0 2.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG38383.1 - 0.054 14.1 0.0 0.094 13.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family CBM_1 PF00734.18 CEG38385.1 - 1.4e-08 34.6 10.7 9.5e-08 31.9 3.2 3.2 3 0 0 3 3 3 2 Fungal cellulose binding domain DUF4371 PF14291.6 CEG38389.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) DXPR_C PF13288.6 CEG38390.1 - 0.19 12.0 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain Spectrin PF00435.21 CEG38392.1 - 2.1 8.9 9.8 0.33 11.4 2.1 2.6 2 0 0 2 2 2 0 Spectrin repeat LRR_6 PF13516.6 CEG38396.1 - 2.9e-14 51.8 18.0 0.0043 17.0 0.0 7.9 8 0 0 8 8 8 5 Leucine Rich repeat zf-C2HC_2 PF13913.6 CEG38396.1 - 2.9e-10 39.8 0.8 3.4e-08 33.2 0.3 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type LRR_1 PF00560.33 CEG38396.1 - 5.6e-05 23.1 7.5 16 6.5 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 CEG38396.1 - 0.00014 22.2 8.6 1.5 9.4 1.3 5.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG38396.1 - 0.0082 15.9 9.3 0.62 9.9 1.1 5.3 5 1 0 5 5 5 2 Leucine rich repeat DAHP_synth_1 PF00793.20 CEG38396.1 - 0.019 13.8 0.0 0.047 12.5 0.0 1.6 1 0 0 1 1 1 0 DAHP synthetase I family NDT80_PhoG PF05224.12 CEG38396.1 - 0.024 14.8 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family WD40 PF00400.32 CEG38397.1 - 3.1e-10 40.5 2.0 0.59 11.1 0.0 6.1 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38397.1 - 0.00031 21.0 0.0 6.2 7.2 0.0 3.9 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3043 PF11241.8 CEG38398.1 - 0.19 11.7 0.7 0.22 11.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CNDH2_C PF16858.5 CEG38399.1 - 6.4e-78 262.6 6.7 6.4e-78 262.6 6.7 1.8 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 CEG38399.1 - 1.5e-36 125.1 0.1 1.5e-36 125.1 0.1 2.7 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Rad21_Rec8_N PF04825.13 CEG38399.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein NPP1 PF05630.11 CEG38402.1 - 4.4e-44 151.0 0.1 5.1e-44 150.7 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF4644 PF15486.6 CEG38402.1 - 0.058 13.2 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Pkinase_Tyr PF07714.17 CEG38404.1 - 1.7e-29 102.9 0.0 6.9e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG38404.1 - 2e-25 89.7 0.0 7.4e-25 87.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DEP PF00610.21 CEG38404.1 - 7.3e-08 32.4 0.0 2.7e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 CEG38405.1 - 8.1e-38 130.3 0.0 1e-26 93.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38405.1 - 1.4e-36 126.1 0.0 2.5e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 CEG38405.1 - 9.7e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 CEG38405.1 - 0.0068 16.4 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEG38405.1 - 0.042 12.9 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CEG38405.1 - 0.098 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MgsA_C PF12002.8 CEG38406.1 - 1.8e-55 187.4 0.0 3.1e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CEG38406.1 - 7.7e-23 80.6 0.1 2.1e-22 79.3 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 CEG38406.1 - 1.5e-15 57.8 0.0 2.7e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG38406.1 - 1.7e-13 50.6 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG38406.1 - 4.6e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEG38406.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CEG38406.1 - 0.00019 21.2 0.0 0.094 12.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 CEG38406.1 - 0.00019 21.8 0.9 0.77 10.1 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CEG38406.1 - 0.00026 21.5 0.0 0.00057 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEG38406.1 - 0.00031 20.5 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNF220 PF15926.5 CEG38406.1 - 0.00049 19.8 0.8 0.0011 18.7 0.1 1.8 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 AAA_22 PF13401.6 CEG38406.1 - 0.0007 19.9 1.3 0.52 10.6 1.3 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CEG38406.1 - 0.00074 19.0 0.1 0.06 12.7 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CEG38406.1 - 0.00092 19.6 1.1 0.041 14.3 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain Rad17 PF03215.15 CEG38406.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 CEG38406.1 - 0.0018 18.4 0.0 0.0053 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 CEG38406.1 - 0.0028 17.1 0.1 0.15 11.5 0.0 2.7 2 1 1 3 3 3 1 Bacterial TniB protein Viral_helicase1 PF01443.18 CEG38406.1 - 0.0047 16.7 0.2 0.022 14.5 0.2 2.1 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CEG38406.1 - 0.0062 15.7 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CEG38406.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain ABC_tran PF00005.27 CEG38406.1 - 0.0079 16.7 0.0 0.017 15.7 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CEG38406.1 - 0.009 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 CEG38406.1 - 0.0092 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 CEG38406.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase MCM PF00493.23 CEG38406.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ResIII PF04851.15 CEG38406.1 - 0.016 15.2 0.1 2 8.4 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CEG38406.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEG38406.1 - 0.03 13.5 0.1 0.15 11.2 0.0 2.1 2 1 1 3 3 2 0 NB-ARC domain AAA_17 PF13207.6 CEG38406.1 - 0.032 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEG38406.1 - 0.041 13.6 0.1 0.21 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEG38406.1 - 0.047 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CEG38406.1 - 0.065 12.5 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 CEG38406.1 - 0.078 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_25 PF13481.6 CEG38406.1 - 0.12 11.9 0.1 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEG38406.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sgf11 PF08209.11 CEG38406.1 - 0.13 11.9 0.6 0.39 10.3 0.6 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) NTPase_1 PF03266.15 CEG38406.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.11 CEG38406.1 - 0.18 11.7 0.0 1.1 9.1 0.0 2.2 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Hydrolase_4 PF12146.8 CEG38407.1 - 5.3e-09 35.7 0.0 5.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG38407.1 - 0.17 11.5 0.3 0.47 10.0 0.3 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold TSC22 PF01166.18 CEG38408.1 - 0.08 13.3 0.1 1.4 9.3 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Ig_C19orf38 PF17737.1 CEG38408.1 - 0.16 12.3 0.1 0.83 10.0 0.0 2.0 2 0 0 2 2 2 0 Ig domain in C19orf38 (HIDE1) bZIP_1 PF00170.21 CEG38408.1 - 0.31 11.2 11.5 0.61 10.2 11.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 CEG38408.1 - 2 8.2 4.6 1.9 8.3 2.4 1.9 2 0 0 2 2 2 0 Septum formation initiator RINT1_TIP1 PF04437.13 CEG38409.1 - 1e-49 169.8 4.1 1e-49 169.8 4.1 2.4 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Spc7 PF08317.11 CEG38409.1 - 0.062 12.2 11.4 0.12 11.2 11.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein CSN5_C PF18323.1 CEG38409.1 - 0.17 12.8 5.5 14 6.7 5.2 3.0 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Glyco_hydro_52 PF03512.13 CEG38409.1 - 0.42 9.5 3.6 0.14 11.0 0.4 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 Syntaxin_2 PF14523.6 CEG38409.1 - 1.1 9.7 9.8 3.8 7.9 1.2 3.2 2 1 1 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.12 CEG38409.1 - 1.1 9.3 6.6 0.69 10.0 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1690 PF07956.11 CEG38409.1 - 2.3 8.6 17.1 0.3 11.5 8.8 2.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF4446 PF14584.6 CEG38409.1 - 2.4 8.2 7.1 3 7.8 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) Fib_alpha PF08702.10 CEG38409.1 - 8.3 6.6 10.3 0.78 9.9 4.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_lid_5 PF17865.1 CEG38411.1 - 0.2 11.8 2.0 0.63 10.1 2.0 1.9 1 1 0 1 1 1 0 Midasin AAA lid domain ORC2 PF04084.14 CEG38413.1 - 8.7e-59 199.1 0.6 1.1e-58 198.8 0.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RWP-RK PF02042.15 CEG38416.1 - 3.7e-20 71.6 0.4 1.6e-19 69.6 0.1 2.3 2 0 0 2 2 2 1 RWP-RK domain Utp11 PF03998.13 CEG38419.1 - 1 9.3 6.7 0.28 11.1 2.2 1.9 1 1 1 2 2 2 0 Utp11 protein AAA_23 PF13476.6 CEG38419.1 - 5.4 7.5 12.0 26 5.2 12.0 2.0 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 CEG38420.1 - 2.3e-107 359.7 20.2 2.3e-107 359.7 20.2 3.3 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEG38420.1 - 0.0021 17.0 0.5 0.034 13.0 0.3 2.7 2 1 0 2 2 2 1 MreB/Mbl protein DP-EP PF08985.11 CEG38420.1 - 0.037 14.2 0.9 8.6 6.6 0.0 3.0 2 0 0 2 2 2 0 DP-EP family PB1 PF00564.24 CEG38421.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 PB1 domain CorA PF01544.18 CEG38422.1 - 1.2e-45 156.1 0.1 3.9e-37 128.1 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 CEG38422.1 - 1.6e-05 25.2 0.2 7.8e-05 23.1 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CEG38422.1 - 0.00041 20.1 1.3 0.0028 17.5 1.3 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG38422.1 - 0.0011 18.3 0.7 0.003 17.0 0.7 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG38422.1 - 0.0012 18.6 0.3 0.13 12.2 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain ATP_bind_2 PF03668.15 CEG38422.1 - 0.0024 17.2 0.1 0.0042 16.4 0.1 1.3 1 0 0 1 1 1 1 P-loop ATPase protein family EF-hand_5 PF13202.6 CEG38422.1 - 0.11 12.0 0.3 0.28 10.8 0.3 1.6 1 0 0 1 1 1 0 EF hand MDD_C PF18376.1 CEG38424.1 - 9.8e-70 234.1 1.0 1.7e-69 233.3 1.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CEG38424.1 - 3.2e-07 30.5 1.3 1e-06 28.9 1.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DnaJ PF00226.31 CEG38425.1 - 4.6e-13 49.1 0.1 3.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 DnaJ domain EF-hand_7 PF13499.6 CEG38426.1 - 7e-07 29.6 0.1 1.2e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG38426.1 - 9e-07 28.3 0.7 0.0091 15.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain RIIa PF02197.17 CEG38426.1 - 1.1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_1 PF00036.32 CEG38426.1 - 8.3e-05 21.9 0.2 0.24 11.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CEG38426.1 - 0.0037 17.6 0.1 0.0093 16.3 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CEG38426.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 CEG38427.1 - 1.8e-25 88.7 5.5 1.1e-09 38.8 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38427.1 - 4.4e-09 36.5 0.1 0.0019 18.5 0.0 4.5 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG38427.1 - 8.3e-05 22.5 0.0 1.4 8.8 0.1 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 CEG38427.1 - 0.0019 18.2 0.0 0.86 9.7 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 CEG38427.1 - 0.0049 15.9 0.1 0.63 8.9 0.0 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CEG38427.1 - 0.13 11.2 0.2 3.7 6.5 0.1 2.2 1 1 1 2 2 2 0 Coatomer WD associated region SMC_hinge PF06470.13 CEG38428.1 - 0.058 13.7 0.4 0.22 11.9 0.4 2.0 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Adaptin_N PF01602.20 CEG38429.1 - 2.4e-120 402.6 14.3 3.6e-120 402.0 10.3 2.2 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CEG38429.1 - 4.5e-20 72.3 14.2 7.2e-20 71.7 0.6 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 CEG38429.1 - 7.2e-15 55.5 0.0 2.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Bap31 PF05529.12 CEG38429.1 - 1.6e-10 40.9 3.8 4.5e-10 39.5 3.8 1.8 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region HEAT_2 PF13646.6 CEG38429.1 - 7.7e-08 32.6 10.4 0.0013 19.1 1.5 4.6 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CEG38429.1 - 8.2e-05 22.5 3.2 0.51 10.7 0.0 4.7 3 1 1 4 4 4 1 HEAT repeat UPF0242 PF06785.11 CEG38429.1 - 0.00031 20.9 8.6 0.0009 19.4 8.6 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus HEAT_EZ PF13513.6 CEG38429.1 - 0.024 15.2 1.7 0.71 10.5 0.1 3.6 3 0 0 3 3 2 0 HEAT-like repeat PHM7_cyt PF14703.6 CEG38429.1 - 0.15 12.2 14.1 0.028 14.6 6.0 2.9 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RGS_DHEX PF18148.1 CEG38429.1 - 1.6 8.9 5.9 4.3 7.5 5.9 1.8 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain DivIC PF04977.15 CEG38429.1 - 2.3 8.1 15.3 0.27 11.0 3.3 3.6 2 1 1 3 3 3 0 Septum formation initiator RasGEF_N_2 PF14663.6 CEG38429.1 - 2.9 8.3 5.7 1.1 9.7 0.0 3.2 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SlyX PF04102.12 CEG38429.1 - 6.8 7.4 8.5 3.1 8.5 1.3 3.1 2 0 0 2 2 2 0 SlyX BLOC1_2 PF10046.9 CEG38429.1 - 9.9 6.5 18.3 3.9 7.8 7.9 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CAP PF00188.26 CEG38431.1 - 1.7e-10 41.8 0.0 4.7e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Oleosin PF01277.17 CEG38431.1 - 0.024 14.4 1.3 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Oleosin DUF1298 PF06974.13 CEG38431.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) CD99L2 PF12301.8 CEG38431.1 - 0.57 10.5 4.1 1.8 8.8 4.1 1.8 1 1 0 1 1 1 0 CD99 antigen like protein 2 CAP PF00188.26 CEG38432.1 - 1.1e-12 48.9 1.8 1.5e-12 48.5 0.3 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 CEG38433.1 - 1.3e-14 55.1 1.0 2.7e-14 54.1 1.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UL45 PF05473.12 CEG38433.1 - 0.086 12.5 1.4 3.2 7.4 0.0 3.1 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like TPR_1 PF00515.28 CEG38434.1 - 2.6e-08 33.3 1.5 0.00055 19.6 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG38434.1 - 1.2e-05 25.0 0.7 0.2 11.9 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG38434.1 - 0.00026 21.2 0.1 0.00069 19.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG38434.1 - 0.0008 19.9 0.3 0.0024 18.3 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38434.1 - 0.0019 17.9 1.6 0.0036 16.9 0.1 2.3 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 CEG38434.1 - 0.0022 18.1 0.2 0.69 10.3 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Med9 PF07544.13 CEG38434.1 - 0.0074 16.4 3.7 0.15 12.1 0.2 3.0 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 TPR_12 PF13424.6 CEG38434.1 - 0.059 13.7 3.3 5.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG38434.1 - 0.079 13.1 0.2 0.22 11.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SRP40_C PF05022.12 CEG38435.1 - 8.2e-23 81.0 0.9 8.2e-23 81.0 0.9 3.3 3 2 0 3 3 3 1 SRP40, C-terminal domain LisH PF08513.11 CEG38435.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 LisH HEXIM PF15313.6 CEG38437.1 - 0.084 13.1 0.4 0.085 13.0 0.4 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein EF-hand_7 PF13499.6 CEG38441.1 - 0.072 13.6 0.0 0.42 11.1 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain pair Sulfate_transp PF00916.20 CEG38443.1 - 2.8e-84 283.1 12.9 4.3e-42 144.2 6.1 2.3 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 CEG38443.1 - 4.5e-14 52.1 0.1 1.1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEG38443.1 - 0.0014 19.0 3.7 0.0014 19.0 3.7 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CEG38443.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF3629 PF12302.8 CEG38443.1 - 0.097 12.1 1.5 0.19 11.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) CoA_binding_3 PF13727.6 CEG38443.1 - 6 6.8 8.3 0.19 11.7 0.2 2.5 2 1 1 3 3 3 0 CoA-binding domain Sulfate_transp PF00916.20 CEG38445.1 - 8.1e-40 136.7 24.4 1.2e-39 136.1 24.4 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 CEG38445.1 - 2.8e-06 27.6 0.1 6.2e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 CEG38445.1 - 3.4e-05 23.4 0.0 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEG38445.1 - 0.0014 19.0 4.6 0.0014 19.0 4.6 4.3 4 1 0 4 4 4 2 Molybdate transporter of MFS superfamily HMG_CoA_synt_N PF01154.17 CEG38447.1 - 2.3e-77 258.8 3.8 8.1e-77 257.0 0.3 2.3 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CEG38447.1 - 7.7e-73 245.5 1.1 1.1e-72 245.0 1.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ketoacyl-synt PF00109.26 CEG38447.1 - 4e-17 62.6 3.3 1.6e-16 60.6 3.3 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEG38447.1 - 7.2e-07 29.0 5.7 1.3e-05 25.0 0.2 3.2 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 CEG38447.1 - 0.003 17.7 0.1 0.035 14.3 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Relaxase PF03432.14 CEG38447.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain PTP_tm PF18861.1 CEG38448.1 - 0.02 14.9 0.1 0.045 13.8 0.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Q_salvage PF10343.9 CEG38449.1 - 5.4e-32 111.5 0.0 9.9e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF2600 PF10776.9 CEG38449.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2600) CNOT11 PF10155.9 CEG38450.1 - 7.1e-55 184.5 6.7 1.5e-54 183.5 6.7 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Frataxin_Cyay PF01491.16 CEG38451.1 - 9.2e-08 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain NADPH_Ox PF08414.10 CEG38451.1 - 0.044 14.1 0.0 3.7 7.9 0.0 2.3 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase Aminotran_4 PF01063.19 CEG38453.1 - 1.5e-15 57.7 0.0 3.6e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV zf-CHCC PF10276.9 CEG38454.1 - 4e-16 58.8 0.5 5.9e-16 58.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Vps35 PF03635.17 CEG38455.1 - 1.3e-214 714.9 23.5 1.5e-214 714.7 23.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 zf-RING_11 PF17123.5 CEG38455.1 - 0.16 11.7 1.2 1.2 9.0 0.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger MSC PF09402.10 CEG38455.1 - 0.55 9.6 3.0 1.3 8.4 3.0 1.6 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Fib_alpha PF08702.10 CEG38456.1 - 0.41 10.8 9.5 1.3 9.2 1.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CEG38456.1 - 1.5 7.6 15.4 0.58 9.0 3.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CEG38456.1 - 7.9 6.5 9.4 4.9 7.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pam17 PF08566.10 CEG38457.1 - 0.24 11.2 4.3 0.26 11.1 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NIF PF03031.18 CEG38458.1 - 0.0058 16.4 0.0 0.021 14.6 0.0 2.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TAF1_subA PF14929.6 CEG38459.1 - 1.5e-14 54.3 0.0 3.1e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_16 PF13432.6 CEG38459.1 - 0.18 12.5 0.1 5.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 CEG38460.1 - 2.1e-24 85.3 20.3 2e-05 25.2 0.3 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38460.1 - 8.4e-11 42.0 6.6 1.5e-05 25.2 0.7 3.9 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG38460.1 - 6e-06 25.5 1.2 0.34 9.8 0.0 4.1 2 2 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Syntaxin PF00804.25 CEG38461.1 - 1.3e-37 129.5 9.7 1.6e-37 129.2 9.7 1.1 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 CEG38461.1 - 0.00048 20.4 6.2 0.00048 20.4 6.2 2.0 2 1 0 2 2 2 1 Syntaxin-like protein PglZ PF08665.12 CEG38461.1 - 0.04 14.0 1.9 0.06 13.4 1.9 1.3 1 0 0 1 1 1 0 PglZ domain Arc_PepC PF06819.11 CEG38461.1 - 0.087 13.0 3.5 0.16 12.1 3.5 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Pepsin-I3 PF06394.13 CEG38461.1 - 0.1 12.8 0.8 0.25 11.6 0.2 1.9 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PAH PF02671.21 CEG38461.1 - 0.13 12.5 3.8 0.094 12.9 1.3 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat Folliculin PF11704.8 CEG38461.1 - 0.26 11.2 2.5 0.49 10.3 2.5 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport YscO-like PF16789.5 CEG38461.1 - 4.7 7.2 15.3 0.27 11.2 9.0 2.1 2 2 0 2 2 2 0 YscO-like protein DnaJ_C PF01556.18 CEG38462.1 - 1.5e-43 148.5 0.1 1.9e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG38462.1 - 1.3e-27 95.7 2.3 2.2e-27 95.0 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CEG38462.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF2046 PF09755.9 CEG38463.1 - 1.5e-29 103.2 43.2 5.6e-29 101.3 43.2 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Baculo_PEP_C PF04513.12 CEG38463.1 - 0.4 10.7 19.2 1.1 9.3 4.4 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF851 PF05867.11 CEG38463.1 - 6.9 6.1 18.7 7.9 5.9 9.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF851) PTRF_SDPR PF15237.6 CEG38465.1 - 0.0018 17.9 1.7 0.0021 17.7 1.7 1.0 1 0 0 1 1 1 1 PTRF/SDPR family Cep57_CLD PF14073.6 CEG38468.1 - 0.99 9.4 12.8 0.27 11.2 1.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 WD40 PF00400.32 CEG38470.1 - 1.5e-21 76.2 11.3 0.00015 22.5 0.0 9.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CEG38470.1 - 6e-10 38.6 8.8 1.7e-09 37.2 8.8 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 CEG38470.1 - 1.9e-06 28.1 2.8 0.0011 19.2 0.3 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CEG38470.1 - 0.0069 16.4 0.0 0.1 12.7 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region zinc_ribbon_16 PF17034.5 CEG38470.1 - 0.025 14.8 18.3 0.032 14.5 7.0 2.7 1 1 1 2 2 2 0 Zinc-ribbon like family zf-CHY PF05495.12 CEG38470.1 - 0.064 13.7 4.9 0.14 12.7 4.9 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-rbx1 PF12678.7 CEG38470.1 - 6.2 7.2 11.9 9.1 6.7 10.5 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Sel1 PF08238.12 CEG38471.1 - 8.1e-39 131.2 29.0 2.9e-06 27.8 3.6 9.3 10 0 0 10 10 10 7 Sel1 repeat Laminin_G_3 PF13385.6 CEG38471.1 - 5e-09 36.5 0.2 1.8e-08 34.7 0.0 2.1 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Methyltransf_15 PF09445.10 CEG38472.1 - 2e-36 125.1 1.1 3e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CEG38472.1 - 5.9e-07 29.4 2.6 8.8e-06 25.5 0.3 3.1 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 CEG38472.1 - 1.1e-06 28.6 2.0 4.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CEG38472.1 - 5.2e-06 26.3 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEG38472.1 - 6.3e-06 26.0 0.1 2.2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 CEG38472.1 - 8.1e-06 25.2 0.0 2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 CEG38472.1 - 2.9e-05 24.7 0.0 0.00011 22.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEG38472.1 - 0.00014 21.8 0.1 0.00045 20.2 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38472.1 - 0.00043 20.9 0.0 0.0015 19.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG38472.1 - 0.00055 19.4 0.2 0.00055 19.4 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.15 CEG38472.1 - 0.00077 19.2 0.1 0.06 13.0 0.0 2.9 2 1 1 3 3 3 1 D12 class N6 adenine-specific DNA methyltransferase RNase_Zc3h12a PF11977.8 CEG38472.1 - 0.024 14.4 2.3 0.05 13.4 2.3 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain MTS PF05175.14 CEG38472.1 - 0.027 14.0 0.2 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DUF3573 PF12097.8 CEG38472.1 - 0.16 10.8 3.2 0.28 10.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) UQ_con PF00179.26 CEG38474.1 - 2.4e-44 150.4 0.0 2.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG38474.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.6 1 1 1 2 2 2 0 RWD domain IFT20 PF14931.6 CEG38475.1 - 8.1e-38 129.3 11.9 9e-38 129.1 11.9 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 TMCO5 PF14992.6 CEG38475.1 - 0.0063 16.1 11.2 0.0073 15.9 11.2 1.0 1 0 0 1 1 1 1 TMCO5 family F-112 PF09645.10 CEG38475.1 - 0.041 14.0 2.3 0.037 14.1 1.2 1.4 1 1 0 1 1 1 0 F-112 protein CSN7a_helixI PF18392.1 CEG38475.1 - 0.24 11.3 2.3 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain DUF3450 PF11932.8 CEG38475.1 - 2.4 7.4 13.7 1.4 8.2 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Histone PF00125.24 CEG38476.1 - 8.8e-54 181.4 1.9 9.7e-54 181.2 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CEG38476.1 - 0.0001 22.9 1.0 0.00012 22.7 1.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CEG38476.1 - 0.00047 20.2 0.7 0.00063 19.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEG38476.1 - 0.00048 20.5 0.0 0.00073 19.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CEG38476.1 - 0.075 13.1 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CEG38477.1 - 5.5e-37 127.1 4.9 1.8e-18 67.2 1.5 2.0 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CEG38477.1 - 8.8e-05 23.1 1.9 0.0001 22.9 1.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CEG38477.1 - 0.05 14.0 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein Atx10homo_assoc PF09759.9 CEG38478.1 - 2.7e-32 110.7 0.2 2.7e-32 110.7 0.2 3.3 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_72 PF03198.14 CEG38481.1 - 7.8e-18 64.8 0.3 1e-17 64.4 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase PA PF02225.22 CEG38482.1 - 2.9e-13 49.7 0.0 7.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 PA domain ZNRF_3_ecto PF18212.1 CEG38482.1 - 0.021 14.8 0.2 1.6 8.7 0.2 2.7 2 0 0 2 2 2 0 ZNRF-3 Ectodomain PRMT5 PF05185.16 CEG38483.1 - 2e-67 226.4 0.0 2.8e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CEG38483.1 - 1.4e-66 224.3 0.0 2.1e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CEG38483.1 - 1.3e-53 181.5 0.5 2.4e-53 180.6 0.5 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_31 PF13847.6 CEG38483.1 - 0.00079 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38483.1 - 0.0032 18.2 0.0 0.0073 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CEG38483.1 - 0.097 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF2076 PF09849.9 CEG38484.1 - 0.25 11.3 5.9 0.32 11.0 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SUa-2TM PF18179.1 CEG38485.1 - 0.043 13.1 0.0 0.045 13.1 0.0 1.0 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain LPMO_10 PF03067.15 CEG38487.1 - 2e-10 41.6 0.0 7.2e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 CEG38487.1 - 0.009 16.0 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 TMEM119 PF15724.5 CEG38487.1 - 0.3 11.1 8.0 0.47 10.5 8.0 1.2 1 0 0 1 1 1 0 TMEM119 family COPR5 PF15340.6 CEG38488.1 - 0.2 12.3 0.0 0.2 12.3 0.0 1.0 1 0 0 1 1 1 0 Cooperator of PRMT5 family PH PF00169.29 CEG38490.1 - 5.6e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 PH domain CCDC106 PF15794.5 CEG38490.1 - 0.0016 18.2 1.3 0.0024 17.6 1.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 GDC-P PF02347.16 CEG38492.1 - 3.6e-189 629.1 0.1 5.7e-174 579.0 0.0 3.2 2 1 1 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CEG38492.1 - 2.6e-08 33.2 0.1 9e-07 28.2 0.1 2.7 3 0 0 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEG38492.1 - 0.00027 20.3 0.3 0.00069 19.0 0.2 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase FdsD PF11390.8 CEG38494.1 - 0.0056 17.0 0.6 0.018 15.4 0.2 1.9 2 0 0 2 2 2 1 NADH-dependant formate dehydrogenase delta subunit FdsD Pap_E4 PF02711.14 CEG38494.1 - 0.31 12.0 5.5 0.18 12.8 2.2 2.1 2 0 0 2 2 2 0 E4 protein Metallophos PF00149.28 CEG38497.1 - 7.7e-09 36.3 1.5 7.7e-09 36.3 1.5 1.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG38497.1 - 0.0015 18.8 0.3 0.13 12.4 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2749 PF10907.8 CEG38497.1 - 0.028 14.6 0.5 0.12 12.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF515 PF04415.12 CEG38497.1 - 4.6 5.5 5.4 7.4 4.8 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ANAPC_CDC26 PF10471.9 CEG38499.1 - 0.56 11.1 7.9 1.5 9.7 7.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Galactosyl_T PF01762.21 CEG38500.1 - 0.021 14.6 0.1 0.085 12.7 0.0 1.9 1 1 1 2 2 2 0 Galactosyltransferase AMOP PF03782.17 CEG38501.1 - 0.044 13.9 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 AMOP domain GAF PF01590.26 CEG38502.1 - 0.0008 20.0 0.1 0.0025 18.4 0.1 1.9 1 0 0 1 1 1 1 GAF domain BK_channel_a PF03493.18 CEG38504.1 - 3.6e-14 52.7 0.0 8.5e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CEG38504.1 - 9e-14 51.2 5.4 9.2e-14 51.2 2.3 2.5 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 CEG38504.1 - 8.2e-09 35.0 12.4 1.4e-08 34.3 11.9 1.6 1 1 1 2 2 2 1 Ion transport protein Apolipoprotein PF01442.18 CEG38504.1 - 9.9e-06 25.5 4.6 0.00038 20.4 4.6 2.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ThiD2 PF17792.1 CEG38504.1 - 0.0056 17.1 1.4 0.15 12.5 0.1 2.6 1 1 1 2 2 2 1 ThiD2 family Spc7 PF08317.11 CEG38504.1 - 0.024 13.5 3.8 0.044 12.7 3.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CREPT PF16566.5 CEG38504.1 - 0.17 12.0 3.5 0.48 10.6 3.5 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Laminin_II PF06009.12 CEG38504.1 - 0.25 11.4 2.3 0.52 10.3 0.7 2.3 1 1 1 2 2 2 0 Laminin Domain II AKNA PF12443.8 CEG38504.1 - 0.67 10.6 4.8 0.57 10.9 0.3 2.6 1 1 0 2 2 2 0 AT-hook-containing transcription factor Baculo_p33 PF05214.12 CEG38505.1 - 0.014 15.2 0.3 0.024 14.4 0.3 1.4 1 0 0 1 1 1 0 Baculovirus P33 Vesiculo_matrix PF06326.12 CEG38506.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Vesiculovirus matrix protein Cpn60_TCP1 PF00118.24 CEG38507.1 - 4.5e-93 312.5 13.3 1.4e-92 310.9 13.3 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AA_permease_2 PF13520.6 CEG38508.1 - 5.6e-23 81.5 35.7 7.2e-23 81.1 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG38508.1 - 5.9e-11 41.6 29.9 1e-10 40.9 29.5 1.6 1 1 0 1 1 1 1 Amino acid permease UVR PF02151.19 CEG38509.1 - 3.9 7.4 49.0 0.029 14.1 3.1 6.0 6 0 0 6 6 6 0 UvrB/uvrC motif rve PF00665.26 CEG38510.1 - 2.2e-06 27.8 0.0 2.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain FYVE PF01363.21 CEG38514.1 - 1e-14 54.4 15.7 2.5e-14 53.2 15.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 CEG38514.1 - 1.6e-11 44.7 0.0 4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 DUSP domain FYVE_2 PF02318.16 CEG38514.1 - 3.1 8.1 12.3 9.6 6.5 12.3 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 CEG38514.1 - 9.8 6.4 11.8 0.58 10.3 2.0 2.8 1 1 1 2 2 2 0 B-box zinc finger CAP_GLY PF01302.25 CEG38515.1 - 1.1e-22 79.8 0.1 2e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain SPX PF03105.19 CEG38517.1 - 0.00029 20.9 0.6 0.00033 20.7 0.6 1.1 1 0 0 1 1 1 1 SPX domain ABC1 PF03109.16 CEG38519.1 - 1.1e-24 86.9 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CEG38519.1 - 8.4e-05 22.2 0.1 0.41 10.2 0.0 3.3 3 0 0 3 3 3 2 RIO1 family APH PF01636.23 CEG38519.1 - 0.0093 15.9 0.2 0.061 13.2 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family DUF5535 PF17687.1 CEG38522.1 - 0.18 12.0 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5535) 4HBT_2 PF13279.6 CEG38523.1 - 9e-21 74.6 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily AAA_11 PF13086.6 CEG38524.1 - 4.7e-72 242.9 14.0 4.7e-72 242.9 14.0 4.8 2 2 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CEG38524.1 - 8.2e-62 208.4 0.2 3.4e-60 203.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.7 CEG38524.1 - 6.8e-19 67.6 3.7 6.8e-19 67.6 3.7 3.3 3 0 0 3 3 3 1 SEN1 N terminal Med26 PF08711.11 CEG38524.1 - 7.7e-11 41.8 3.1 2.4e-10 40.2 3.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain AAA_30 PF13604.6 CEG38524.1 - 1.3e-09 38.0 0.7 0.0002 21.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CEG38524.1 - 1.8e-07 31.6 0.1 0.041 14.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG38524.1 - 0.12 12.8 0.5 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF1640 PF07798.11 CEG38525.1 - 3e-17 63.2 12.2 4.4e-16 59.4 12.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) YppF PF14178.6 CEG38525.1 - 0.044 13.7 0.4 0.13 12.2 0.4 1.8 2 0 0 2 2 2 0 YppF-like protein Enkurin PF13864.6 CEG38525.1 - 0.5 10.8 8.6 1.7 9.1 0.6 2.9 1 1 1 3 3 3 0 Calmodulin-binding Epimerase PF01370.21 CEG38526.1 - 3e-12 46.5 0.0 2.5e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEG38526.1 - 1.8e-10 40.4 0.0 1.8e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEG38526.1 - 1.5e-08 34.8 0.0 3.2e-08 33.7 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CEG38526.1 - 1.1e-07 31.1 0.0 0.0002 20.5 0.0 2.3 1 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CEG38526.1 - 1.2e-06 28.3 0.1 6.9e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CEG38526.1 - 0.14 11.3 0.1 12 5.0 0.0 2.6 2 1 1 3 3 3 0 Male sterility protein AI-2E_transport PF01594.16 CEG38527.1 - 6.6e-29 101.1 33.7 2.8e-26 92.5 23.4 3.1 2 1 0 2 2 2 2 AI-2E family transporter RVT_2 PF07727.14 CEG38530.1 - 5.9e-05 22.8 0.0 7.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FSH1 PF03959.13 CEG38531.1 - 3.1e-49 167.5 0.0 3.5e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CEG38531.1 - 0.005 16.4 0.0 0.0062 16.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BTD PF09270.10 CEG38531.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Abhydrolase_2 PF02230.16 CEG38531.1 - 0.082 12.7 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 CEG38531.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Glyco_transf_41 PF13844.6 CEG38532.1 - 3.8e-78 263.0 0.3 5.7e-47 160.2 0.0 2.7 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_2 PF07719.17 CEG38532.1 - 4.3e-23 79.5 32.8 3e-05 23.8 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEG38532.1 - 4e-19 69.0 30.1 1.8e-07 31.7 0.4 6.4 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG38532.1 - 6.1e-15 54.3 27.9 0.00036 20.2 0.0 10.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG38532.1 - 7.1e-15 54.4 25.8 0.007 17.1 0.4 8.9 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CEG38532.1 - 2.2e-14 53.5 38.1 4.2e-06 27.0 7.9 8.2 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEG38532.1 - 1.1e-13 51.4 29.6 3.1e-05 24.4 0.0 6.9 5 3 3 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG38532.1 - 2.2e-13 49.2 9.8 0.0025 17.9 0.0 8.4 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38532.1 - 2e-12 46.6 23.1 0.013 15.2 0.0 8.8 6 2 3 9 9 9 5 TPR repeat TPR_17 PF13431.6 CEG38532.1 - 1.4e-11 44.0 16.0 0.008 16.5 0.0 8.1 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG38532.1 - 2.5e-07 30.2 8.3 4.4 7.6 0.0 7.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG38532.1 - 4.4e-06 26.8 0.4 0.0008 19.5 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG38532.1 - 0.00014 21.6 4.0 0.00014 21.6 4.0 8.0 9 1 0 9 9 9 2 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 CEG38532.1 - 0.00014 21.5 0.0 0.00056 19.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 HrpB1_HrpK PF09613.10 CEG38532.1 - 0.00036 20.2 4.1 1.1 8.9 0.0 4.5 4 1 0 4 4 4 2 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 CEG38532.1 - 0.002 18.3 0.2 0.002 18.3 0.2 4.0 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG38532.1 - 0.0026 18.3 16.7 7.5 7.4 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat RPN7 PF10602.9 CEG38532.1 - 0.0065 16.2 3.3 4.2 7.1 0.0 4.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 Glyco_trans_4_3 PF12000.8 CEG38532.1 - 0.029 14.1 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 4 group Rapsyn_N PF10579.9 CEG38532.1 - 0.15 12.2 0.1 1.7 8.8 0.0 2.8 3 0 0 3 3 2 0 Rapsyn N-terminal myristoylation and linker region TPR_20 PF14561.6 CEG38532.1 - 0.4 11.0 17.6 3.3 8.1 0.0 6.3 5 2 3 8 8 8 0 Tetratricopeptide repeat DALR_1 PF05746.15 CEG38532.1 - 0.83 9.8 5.9 3.6 7.8 2.2 2.8 2 0 0 2 2 2 0 DALR anticodon binding domain Transp_cyt_pur PF02133.15 CEG38534.1 - 0.064 12.0 0.0 0.068 11.9 0.0 1.0 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin MIF4G_like PF09088.11 CEG38535.1 - 6.9e-25 87.9 0.2 6.1e-24 84.9 0.2 2.2 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 CEG38535.1 - 4.6e-24 85.3 0.0 1.1e-23 84.0 0.0 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 CEG38535.1 - 0.00086 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain SHNi-TPR PF10516.9 CEG38536.1 - 8.6e-11 41.1 0.1 1.9e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_8 PF13181.6 CEG38536.1 - 8.4e-09 35.0 0.4 0.012 15.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG38536.1 - 4.9e-05 23.0 0.3 0.18 11.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG38536.1 - 0.00017 21.8 4.8 0.47 10.8 0.2 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG38536.1 - 0.00035 20.5 2.2 0.096 12.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG38536.1 - 0.0039 17.0 1.0 0.25 11.3 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_lid_7 PF17867.1 CEG38536.1 - 0.13 12.5 0.1 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 Midasin AAA lid domain TPR_17 PF13431.6 CEG38536.1 - 0.16 12.4 0.7 65 4.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG38536.1 - 0.18 12.7 3.3 12 7.0 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat RLL PF10036.9 CEG38536.1 - 0.23 11.3 5.4 0.46 10.3 5.3 1.5 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein Synaptobrevin PF00957.21 CEG38537.1 - 3.6e-25 87.6 3.3 6.1e-25 86.8 3.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEG38537.1 - 8.5e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain PRIMA1 PF16101.5 CEG38537.1 - 0.048 13.7 0.2 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MCU PF04678.13 CEG38537.1 - 0.091 12.9 1.3 0.11 12.5 1.3 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF1768 PF08719.11 CEG38537.1 - 0.22 11.7 1.7 0.49 10.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1768) Aldo_ket_red PF00248.21 CEG38538.1 - 0.026 13.7 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Aldo/keto reductase family Ricin_B_lectin PF00652.22 CEG38542.1 - 1.4e-09 38.3 0.5 3.3e-09 37.1 0.5 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEG38542.1 - 0.00084 20.0 0.5 0.63 10.8 0.0 3.3 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 CEG38542.1 - 0.05 13.2 0.4 12 5.4 0.0 2.4 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain FtsK_SpoIIIE PF01580.18 CEG38544.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 CEG38544.1 - 0.075 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_D5 PF03288.16 CEG38545.1 - 0.011 16.2 0.2 1.1 9.8 0.0 2.1 1 1 1 2 2 2 0 Poxvirus D5 protein-like Peptidase_S74 PF13884.6 CEG38547.1 - 3.8e-08 33.5 0.2 9.9e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Chaperone of endosialidase ubiquitin PF00240.23 CEG38547.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family DGF-1_C PF11040.8 CEG38551.1 - 0.14 12.2 0.3 0.36 10.8 0.3 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus pRN1_helical PF13010.6 CEG38552.1 - 0.052 13.5 0.2 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 Primase helical domain RNase_P_Rpp14 PF01900.19 CEG38556.1 - 7.8e-06 26.1 0.0 1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RICTOR_N PF14664.6 CEG38557.1 - 9.9e-87 291.3 3.4 1.6e-86 290.7 3.4 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CEG38557.1 - 2e-28 98.2 1.0 2e-27 95.0 1.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CEG38557.1 - 5.7e-27 93.8 0.1 1.2e-23 83.1 0.0 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CEG38557.1 - 1.3e-18 67.3 2.6 7.5e-18 64.9 0.0 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 CEG38557.1 - 1.8e-06 28.3 0.5 0.048 14.2 0.0 4.1 2 1 1 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.6 CEG38557.1 - 0.026 14.9 4.8 8.1 6.9 0.1 5.2 4 1 1 5 5 5 0 HEAT repeats Arm PF00514.23 CEG38557.1 - 0.19 11.8 12.3 1.3e+02 2.8 0.1 7.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat rve PF00665.26 CEG38559.1 - 7.8e-14 51.9 0.1 2e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG38559.1 - 4.8e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Josephin PF02099.17 CEG38560.1 - 0.039 14.0 0.2 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 Josephin PALP PF00291.25 CEG38564.1 - 0.015 14.7 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TUDOR_5 PF18359.1 CEG38566.1 - 5.2e-05 22.8 3.6 1.5 8.5 0.0 4.5 4 0 0 4 4 4 2 Histone methyltransferase Tudor domain 1 SR-25 PF10500.9 CEG38566.1 - 0.0009 18.9 18.1 0.0009 18.9 18.1 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4537 PF15057.6 CEG38566.1 - 0.018 15.0 0.7 6.1 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) ECR1_N PF14382.6 CEG38566.1 - 0.023 14.5 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region EF-hand_6 PF13405.6 CEG38566.1 - 0.054 13.4 0.1 1.2 9.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain zf-RanBP PF00641.18 CEG38566.1 - 0.063 12.6 11.8 0.33 10.3 3.4 2.7 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1325 PF07039.11 CEG38566.1 - 0.088 12.9 0.2 8.8 6.4 0.0 2.8 1 1 2 3 3 3 0 SGF29 tudor-like domain DZR PF12773.7 CEG38566.1 - 0.56 10.3 6.7 0.86 9.7 1.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon ISN1 PF06437.11 CEG38567.1 - 0.022 13.7 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase ASH PF15780.5 CEG38572.1 - 7e-08 32.6 3.3 0.11 12.7 0.0 5.0 5 0 0 5 5 5 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CEG38572.1 - 7.9e-06 26.0 0.2 0.00017 21.8 0.0 3.2 2 0 0 2 2 2 1 Transmembrane protein 131-like DUF1573 PF07610.11 CEG38572.1 - 0.0069 16.4 0.0 0.068 13.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1573) DUF2791 PF10923.8 CEG38572.1 - 0.058 12.2 0.1 0.87 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Aminotran_5 PF00266.19 CEG38573.1 - 1.8e-13 50.2 0.0 1.5e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DUF3592 PF12158.8 CEG38574.1 - 0.47 10.5 2.2 0.6 10.2 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) UCH PF00443.29 CEG38575.1 - 7.1e-57 192.8 0.2 1.3e-56 191.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG38575.1 - 1.1e-28 100.8 0.1 3.5e-28 99.1 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG38575.1 - 0.00047 19.8 0.3 0.18 11.6 0.0 3.2 2 0 0 2 2 2 2 Ubiquitin family PBP_sp32 PF07222.12 CEG38575.1 - 0.0026 17.2 0.7 0.0072 15.8 0.7 1.7 1 0 0 1 1 1 1 Proacrosin binding protein sp32 Kinesin PF00225.23 CEG38576.1 - 3e-105 351.9 0.7 6.7e-105 350.7 0.7 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG38576.1 - 1.8e-22 79.9 0.1 5.7e-22 78.3 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding Cytochrom_C_2 PF01322.20 CEG38576.1 - 1.2 10.1 9.0 0.066 14.1 1.4 2.6 2 1 0 2 2 2 0 Cytochrome C' DUF2407_C PF13373.6 CEG38577.1 - 4.1e-24 85.4 0.0 6.4e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 CEG38577.1 - 1.7e-13 50.1 0.2 3e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CEG38577.1 - 9.5e-07 29.3 0.2 2.1e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CEG38577.1 - 5.3e-05 23.2 2.4 0.0049 16.9 0.5 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 CEG38577.1 - 0.00022 21.0 0.3 0.00044 20.0 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CEG38577.1 - 0.013 15.6 0.1 0.023 14.8 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4203 PF13886.6 CEG38577.1 - 0.092 12.4 1.4 0.14 11.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) CbtA PF09490.10 CEG38577.1 - 0.11 12.3 0.5 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) NEMP PF10225.9 CEG38577.1 - 0.35 10.5 2.0 3.2 7.3 1.0 2.1 2 0 0 2 2 2 0 NEMP family PTPS PF01242.19 CEG38578.1 - 3.9e-20 72.1 0.0 6.2e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase zf-BED PF02892.15 CEG38578.1 - 0.011 15.7 0.3 0.023 14.7 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger PyrI_C PF02748.15 CEG38578.1 - 0.031 14.2 0.1 0.076 12.9 0.1 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DEAD PF00270.29 CEG38579.1 - 8.4e-48 162.5 0.0 6.5e-47 159.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG38579.1 - 8.5e-33 113.0 0.2 4.4e-32 110.7 0.3 2.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG38579.1 - 0.0027 17.8 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEG38579.1 - 0.021 14.0 0.2 0.031 13.5 0.2 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Tai4 PF16695.5 CEG38581.1 - 0.029 14.9 0.8 0.075 13.6 0.8 1.8 1 1 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein zf-CCHC PF00098.23 CEG38584.1 - 2.6e-05 24.1 0.7 4.7e-05 23.3 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle ANAPC4_WD40 PF12894.7 CEG38585.1 - 1.8e-11 44.2 0.3 7.8e-06 26.1 0.0 5.9 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SNAP PF14938.6 CEG38585.1 - 1.6e-08 34.3 19.2 0.00092 18.7 0.1 4.6 4 1 1 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 CEG38585.1 - 7.1e-07 28.9 32.7 0.15 12.2 0.3 10.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG38585.1 - 1e-06 29.0 17.3 0.0057 17.4 0.1 8.1 8 1 1 9 9 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CEG38585.1 - 1.1e-06 28.0 5.6 0.11 11.5 0.2 4.1 3 0 0 3 3 3 3 Coatomer WD associated region Clathrin PF00637.20 CEG38585.1 - 1.5e-06 28.2 13.9 1.2 9.0 0.0 6.0 5 1 0 6 6 5 2 Region in Clathrin and VPS WD40 PF00400.32 CEG38585.1 - 1.3e-05 25.9 0.8 8.4 7.4 0.0 6.6 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_19 PF14559.6 CEG38585.1 - 6e-05 23.5 12.5 12 6.5 0.0 8.6 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG38585.1 - 0.00013 21.6 24.4 0.49 10.3 0.5 8.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG38585.1 - 0.00021 21.3 15.4 0.8 10.1 0.5 8.3 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG38585.1 - 0.00041 20.2 27.2 0.16 12.0 0.1 9.9 9 2 2 11 11 10 2 Tetratricopeptide repeat Ge1_WD40 PF16529.5 CEG38585.1 - 0.00063 18.8 0.0 0.18 10.7 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RPN7 PF10602.9 CEG38585.1 - 0.002 17.9 18.5 0.04 13.6 0.5 6.4 6 1 0 6 6 6 1 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CEG38585.1 - 0.0031 17.7 24.0 1.7 8.9 0.3 8.0 6 2 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CEG38585.1 - 0.0042 17.3 21.3 0.021 15.1 1.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38585.1 - 0.013 15.2 6.7 3.5 7.4 0.1 5.5 6 0 0 6 6 5 0 TPR repeat TPR_MalT PF17874.1 CEG38585.1 - 0.13 11.6 10.1 0.36 10.2 5.9 3.6 2 2 0 2 2 2 0 MalT-like TPR region SusD_RagB PF07980.11 CEG38585.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 SusD family TPR_6 PF13174.6 CEG38585.1 - 0.35 11.6 20.6 35 5.3 0.1 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 CEG38585.1 - 0.54 10.6 12.0 0.26 11.6 1.2 5.6 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.6 CEG38585.1 - 0.73 10.1 7.3 0.43 10.8 0.3 4.0 4 0 0 4 4 4 0 PPR repeat family MIT PF04212.18 CEG38585.1 - 1.1 9.3 12.9 7.1 6.8 0.0 5.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 CEG38585.1 - 5.1 8.0 6.6 1.8e+02 3.3 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat CPL PF08144.11 CEG38586.1 - 6.7e-14 52.4 7.4 1.5e-11 44.8 0.2 4.7 3 3 1 4 4 4 2 CPL (NUC119) domain PUF PF00806.19 CEG38586.1 - 2e-06 27.2 0.1 0.0069 16.0 0.0 4.4 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat DUF4602 PF15375.6 CEG38587.1 - 2.5e-19 69.9 10.2 2.5e-19 69.9 10.2 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4602) RNase_HII PF01351.18 CEG38588.1 - 2.3e-37 128.8 0.0 5.2e-37 127.6 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease HII Myosin_head PF00063.21 CEG38589.1 - 2.2e-106 356.7 0.1 3.3e-106 356.1 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 CEG38589.1 - 7.9e-12 45.2 11.5 7.9e-12 45.2 11.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger IQ PF00612.27 CEG38589.1 - 0.1 12.4 0.1 0.1 12.4 0.1 6.3 6 0 0 6 6 6 0 IQ calmodulin-binding motif zf-AN1 PF01428.16 CEG38589.1 - 4.7 7.5 13.8 17 5.7 13.8 1.9 1 0 0 1 1 1 0 AN1-like Zinc finger CTP_transf_like PF01467.26 CEG38591.1 - 8.1e-07 29.3 0.0 3.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 CEG38591.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase MacB_PCD PF12704.7 CEG38591.1 - 0.059 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain PET10 PF17316.2 CEG38592.1 - 0.089 12.3 0.5 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 Petite colonies protein 10 DAGK_cat PF00781.24 CEG38593.1 - 7.3e-25 87.0 0.0 1.2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Fascin PF06268.13 CEG38596.1 - 0.0089 16.2 0.1 0.027 14.7 0.1 1.8 1 1 0 1 1 1 1 Fascin domain ubiquitin PF00240.23 CEG38597.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF104 PF01954.16 CEG38597.1 - 0.072 13.5 2.5 0.28 11.6 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function DUF104 Ribosomal_S4e PF00900.20 CEG38598.1 - 2.2e-31 107.5 0.9 4.4e-31 106.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CEG38598.1 - 8.3e-24 83.0 0.0 1.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CEG38598.1 - 5.7e-20 71.1 9.5 6.5e-20 71.0 8.2 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CEG38598.1 - 3.6e-07 29.8 0.3 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 S4 domain DsbG_N PF18257.1 CEG38598.1 - 0.0017 18.4 0.1 4.2 7.6 0.0 3.2 2 1 1 3 3 3 2 Disulfide isomerase DsbG N-terminal KOW PF00467.29 CEG38598.1 - 0.0023 17.8 0.4 0.0023 17.8 0.4 3.3 5 0 0 5 5 5 1 KOW motif HAS-barrel PF09378.10 CEG38598.1 - 0.072 13.2 0.5 4.7 7.4 0.2 2.8 2 1 0 2 2 2 0 HAS barrel domain MtN3_slv PF03083.16 CEG38599.1 - 5.4e-31 106.5 4.6 1.7e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CEG38599.1 - 0.00042 20.0 2.2 2.7 7.8 0.1 3.5 3 0 0 3 3 3 2 PQ loop repeat O-antigen_lig PF13425.6 CEG38599.1 - 0.011 14.6 0.4 0.4 9.4 0.4 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MARVEL PF01284.23 CEG38599.1 - 0.36 10.9 5.1 15 5.6 4.0 3.0 2 1 0 2 2 2 0 Membrane-associating domain Imp-YgjV PF10688.9 CEG38599.1 - 5.1 6.9 8.3 5.5 6.8 3.1 2.8 1 1 1 2 2 2 0 Bacterial inner membrane protein MtN3_slv PF03083.16 CEG38601.1 - 5.4e-31 106.5 4.6 1.7e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CEG38601.1 - 0.00042 20.0 2.2 2.7 7.8 0.1 3.5 3 0 0 3 3 3 2 PQ loop repeat O-antigen_lig PF13425.6 CEG38601.1 - 0.011 14.6 0.4 0.4 9.4 0.4 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MARVEL PF01284.23 CEG38601.1 - 0.36 10.9 5.1 15 5.6 4.0 3.0 2 1 0 2 2 2 0 Membrane-associating domain Imp-YgjV PF10688.9 CEG38601.1 - 5.1 6.9 8.3 5.5 6.8 3.1 2.8 1 1 1 2 2 2 0 Bacterial inner membrane protein WYL_3 PF18488.1 CEG38602.1 - 0.00082 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 WYL domain HEAT PF02985.22 CEG38606.1 - 1e-31 106.2 34.0 0.0049 17.0 0.1 13.0 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 CEG38606.1 - 1.7e-30 105.2 14.5 9.8e-10 38.7 0.1 7.1 3 2 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 CEG38606.1 - 9.6e-11 42.1 1.7 0.022 15.3 0.0 7.0 3 3 6 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEG38606.1 - 9.6e-09 35.5 7.5 0.00019 21.5 0.2 5.3 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEG38606.1 - 5.9e-08 33.1 17.1 2.1 8.9 0.0 8.4 8 1 1 9 9 9 3 HEAT-like repeat Adaptin_N PF01602.20 CEG38606.1 - 0.00055 18.6 11.4 0.16 10.5 0.3 4.3 2 2 1 4 4 4 2 Adaptin N terminal region IFRD PF05004.13 CEG38606.1 - 0.00085 18.5 0.1 0.0053 15.9 0.1 2.3 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CEG38606.1 - 0.027 14.6 1.3 28 4.9 0.0 4.2 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 CEG38606.1 - 0.035 13.7 1.0 25 4.3 0.1 4.1 2 1 2 4 4 4 0 CLASP N terminal Cohesin_HEAT PF12765.7 CEG38606.1 - 0.74 10.2 4.1 14 6.0 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Retrotran_gag_2 PF14223.6 CEG38607.1 - 2.5e-27 95.2 0.0 4.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG38607.1 - 4.6e-05 23.3 3.1 9.1e-05 22.4 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG38607.1 - 0.95 9.3 4.0 1.7 8.5 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle HrpB7 PF09486.10 CEG38609.1 - 0.013 15.9 0.4 0.013 15.9 0.4 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 CEG38609.1 - 0.082 13.4 5.5 0.022 15.2 2.5 1.6 2 0 0 2 2 2 0 Fez1 JAB PF01398.21 CEG38610.1 - 1.6e-09 37.8 0.0 4.4e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CCDC23 PF15674.5 CEG38610.1 - 0.21 11.6 3.4 0.44 10.6 3.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 RL10P_insert PF17777.1 CEG38611.1 - 2.7e-21 75.3 0.0 4.5e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CEG38611.1 - 2.6e-18 66.0 0.3 3.8e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribul_P_3_epim PF00834.19 CEG38612.1 - 1.5e-65 220.3 0.1 1.8e-65 220.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CEG38612.1 - 0.0047 16.6 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 CEG38612.1 - 0.03 14.1 0.1 0.7 9.6 0.1 2.3 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.10 CEG38612.1 - 0.034 14.4 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain WD40 PF00400.32 CEG38614.1 - 1.5e-08 35.1 0.5 0.37 11.7 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38614.1 - 0.00049 20.4 0.1 0.041 14.2 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MULE PF10551.9 CEG38615.1 - 1.6e-06 28.4 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain HPS3_C PF14763.6 CEG38615.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal SWIM PF04434.17 CEG38616.1 - 0.0016 18.1 2.5 0.004 16.8 1.7 1.9 2 0 0 2 2 2 1 SWIM zinc finger SSF PF00474.17 CEG38617.1 - 0.00012 21.1 8.4 0.00012 21.1 8.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Tcf25 PF04910.14 CEG38619.1 - 5.5e-66 223.0 4.8 8.3e-66 222.4 4.8 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TFIIF_alpha PF05793.12 CEG38619.1 - 0.56 8.7 17.0 0.73 8.3 17.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2_jaz PF12171.8 CEG38621.1 - 4.5e-09 36.4 0.9 8.8e-09 35.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CEG38621.1 - 0.0069 17.1 0.5 0.012 16.2 0.2 1.5 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CEG38621.1 - 0.015 15.6 0.3 0.031 14.7 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEG38621.1 - 0.17 12.2 0.3 0.17 12.2 0.3 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 CEG38623.1 - 5.2e-26 91.6 0.0 7.2e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38623.1 - 6.4e-15 55.1 0.0 7.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG38623.1 - 1.9e-08 33.5 0.0 1.9e-08 33.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CEG38623.1 - 0.0049 15.9 0.1 0.0076 15.3 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CEG38623.1 - 0.0056 16.6 0.9 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 CEG38624.1 - 3.5e-13 49.7 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38624.1 - 5.9e-13 48.9 0.1 2.3e-11 43.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG38624.1 - 9.1e-12 45.5 0.0 2.6e-10 40.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38624.1 - 6.1e-11 42.9 0.0 1.1e-08 35.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG38624.1 - 5.6e-10 39.9 0.0 1.3e-08 35.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CEG38624.1 - 0.036 13.2 0.0 0.5 9.4 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase DUF3850 PF12961.7 CEG38624.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Cyclin PF08613.11 CEG38625.1 - 1.7e-05 25.3 0.2 0.014 15.7 0.0 2.0 1 1 1 2 2 2 2 Cyclin CLASP_N PF12348.8 CEG38627.1 - 1.2e-45 155.9 24.0 1.8e-29 103.0 4.2 4.8 4 1 0 4 4 4 4 CLASP N terminal HEAT PF02985.22 CEG38627.1 - 4.1e-13 48.4 11.0 0.017 15.3 0.0 9.9 12 0 0 12 12 12 2 HEAT repeat HEAT_2 PF13646.6 CEG38627.1 - 1.4e-12 47.8 3.8 0.11 13.0 0.1 7.2 5 2 1 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 CEG38627.1 - 2.5e-08 34.4 3.7 1.8 9.2 0.0 6.1 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEG38627.1 - 2.7e-05 24.5 1.1 0.31 11.6 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 CEG38627.1 - 0.0017 18.4 16.8 0.15 12.1 1.3 6.4 5 3 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CEG38627.1 - 0.0077 16.2 5.9 11 6.2 0.1 5.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 CEG38627.1 - 0.2 11.6 10.1 0.17 11.9 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) Cohesin_HEAT PF12765.7 CEG38627.1 - 0.58 10.5 3.4 24 5.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion MA3 PF02847.17 CEG38627.1 - 1.2 9.1 8.2 0.29 11.1 0.2 3.9 5 0 0 5 5 5 0 MA3 domain ELMO_CED12 PF04727.13 CEG38628.1 - 8e-40 136.8 0.0 1.4e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family FYVE PF01363.21 CEG38628.1 - 4.2e-17 62.0 11.9 9.2e-17 61.0 11.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 CEG38628.1 - 3.3e-05 24.2 0.0 0.00012 22.4 0.0 2.0 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 CEG38628.1 - 0.0019 18.4 6.3 0.0043 17.3 6.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger GAF PF01590.26 CEG38628.1 - 0.065 13.9 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 GAF domain Kri1_C PF12936.7 CEG38629.1 - 1.3e-26 92.6 6.6 1.3e-26 92.6 6.6 4.3 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 CEG38629.1 - 4.3e-24 85.0 13.2 4.3e-24 85.0 13.2 5.9 5 1 0 5 5 5 1 KRI1-like family TraH_2 PF06871.11 CEG38629.1 - 3.6 7.2 6.7 0.29 10.7 0.1 2.4 2 0 0 2 2 2 0 TraH_2 TSC22 PF01166.18 CEG38630.1 - 0.41 11.0 4.3 2.9 8.3 0.1 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family His_biosynth PF00977.21 CEG38631.1 - 1.1e-42 146.0 0.4 6.5e-42 143.5 0.4 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CEG38631.1 - 1e-16 61.3 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 CEG38631.1 - 6.5e-08 32.6 0.0 6.6e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CEG38631.1 - 1e-06 28.5 0.0 3.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CEG38631.1 - 3.2e-05 23.8 0.1 8.6e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.17 CEG38631.1 - 0.021 13.9 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) NMO PF03060.15 CEG38631.1 - 0.082 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase NT5C PF06941.12 CEG38632.1 - 0.0044 16.9 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ANAPC4 PF12896.7 CEG38633.1 - 1.8e-25 89.6 0.9 5e-25 88.2 0.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CEG38633.1 - 1.5e-17 63.6 0.0 4.6e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ER PF01133.17 CEG38633.1 - 0.043 13.8 0.1 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Enhancer of rudimentary Ion_trans PF00520.31 CEG38634.1 - 1.2e-47 162.3 39.1 1.4e-26 93.3 14.6 2.6 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 CEG38634.1 - 1.5e-21 76.2 14.3 4.6e-13 48.9 3.2 2.9 2 0 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 CEG38634.1 - 2.4e-13 49.9 0.0 1.7e-06 28.0 0.0 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain SRP54 PF00448.22 CEG38635.1 - 4.8e-77 258.0 0.0 7.8e-77 257.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CEG38635.1 - 1.6e-27 96.0 0.1 1.6e-27 96.0 0.1 3.2 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 CEG38635.1 - 4.8e-17 61.9 3.5 1.1e-16 60.7 3.5 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CEG38635.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CEG38635.1 - 2.9e-05 23.7 0.2 0.00048 19.7 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CEG38635.1 - 3.3e-05 23.4 1.2 0.62 9.5 0.0 3.6 2 2 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEG38635.1 - 4.6e-05 23.9 0.0 0.00011 22.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CEG38635.1 - 0.00033 20.4 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2209 PF09974.9 CEG38635.1 - 0.0014 19.0 0.2 0.0034 17.7 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) MeaB PF03308.16 CEG38635.1 - 0.002 17.2 0.0 0.015 14.3 0.0 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CEG38635.1 - 0.003 17.6 0.0 0.0087 16.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 CEG38635.1 - 0.0037 17.5 0.0 0.0073 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 CEG38635.1 - 0.0055 16.6 0.1 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 CEG38635.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase MobB PF03205.14 CEG38635.1 - 0.0065 16.4 0.2 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 CEG38635.1 - 0.0073 16.4 0.1 0.075 13.1 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ResIII PF04851.15 CEG38635.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 CEG38635.1 - 0.019 15.4 0.0 0.073 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG38635.1 - 0.037 14.3 0.1 0.12 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CEG38635.1 - 0.039 14.3 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG38635.1 - 0.078 12.5 0.2 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region 6PF2K PF01591.18 CEG38635.1 - 0.097 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 CEG38635.1 - 0.1 11.9 0.0 0.24 10.6 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin DUF4298 PF14131.6 CEG38635.1 - 0.12 12.4 0.1 7.7 6.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) Thymidylate_kin PF02223.17 CEG38635.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase SelR PF01641.18 CEG38636.1 - 2e-48 163.5 0.1 2.3e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CEG38636.1 - 0.026 14.2 0.2 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DHHC PF01529.20 CEG38637.1 - 6.7e-33 113.6 11.2 6.7e-33 113.6 11.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1272 PF06906.11 CEG38637.1 - 0.24 11.5 7.2 0.7 10.0 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Spt4 PF06093.13 CEG38637.1 - 2.4 8.3 5.5 4.1 7.6 5.5 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Ank_4 PF13637.6 CEG38638.1 - 8.3e-13 48.6 0.3 4.5e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG38638.1 - 1.2e-10 41.8 0.3 0.00044 20.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG38638.1 - 1.3e-09 38.1 0.7 0.00037 20.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG38638.1 - 1.1e-07 32.0 0.2 0.018 15.5 0.1 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CEG38638.1 - 9.3e-06 25.6 1.7 0.01 16.3 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat PDZ_6 PF17820.1 CEG38638.1 - 0.044 13.6 0.5 0.44 10.4 0.1 2.7 3 0 0 3 3 3 0 PDZ domain gag_pre-integrs PF13976.6 CEG38640.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 GAG-pre-integrase domain Cellulase PF00150.18 CEG38641.1 - 3.4e-19 69.3 0.6 4.4e-19 69.0 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 CEG38642.1 - 3.7e-60 203.5 0.0 6.3e-40 137.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38642.1 - 2.8e-29 102.2 0.0 8.5e-25 87.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.29 CEG38642.1 - 1.2e-21 76.6 0.0 2.1e-12 46.9 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CEG38642.1 - 1.6e-08 34.2 0.0 5.7e-05 22.6 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CEG38642.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG38642.1 - 7.2e-05 22.2 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG38642.1 - 0.0021 17.7 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CEG38642.1 - 0.0046 15.8 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CEG38642.1 - 0.0083 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 TcfC PF16967.5 CEG38642.1 - 0.048 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 E-set like domain Cupin_2 PF07883.11 CEG38642.1 - 0.1 12.3 1.0 8.7 6.1 0.0 3.4 2 1 1 3 3 3 0 Cupin domain PPR PF01535.20 CEG38644.1 - 2e-12 46.5 4.8 2.2 8.7 0.0 8.0 8 0 0 8 8 8 5 PPR repeat PPR_2 PF13041.6 CEG38644.1 - 6.2e-08 32.7 10.9 0.11 12.7 0.2 6.6 6 1 1 7 7 7 3 PPR repeat family SPOB_a PF14689.6 CEG38644.1 - 0.084 12.6 0.2 24 4.7 0.0 3.7 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain RIIa PF02197.17 CEG38645.1 - 0.009 15.7 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MHB PF16525.5 CEG38645.1 - 0.095 13.0 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 Haemophore, haem-binding Pkinase PF00069.25 CEG38646.1 - 7.2e-57 192.7 0.0 1e-54 185.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38646.1 - 8.7e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CEG38646.1 - 1.2e-07 31.9 0.0 2.6e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG38646.1 - 0.0025 16.7 0.1 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEG38646.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2459 PF09601.10 CEG38646.1 - 0.0099 15.7 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2459) RIO1 PF01163.22 CEG38646.1 - 0.033 13.8 0.2 0.062 12.9 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CEG38646.1 - 0.035 13.7 0.3 0.058 13.0 0.3 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 CEG38646.1 - 0.14 11.7 1.2 1.3 8.5 0.0 2.2 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL RVP_2 PF08284.11 CEG38648.1 - 8.8e-08 32.0 0.0 9.8e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CEG38648.1 - 1.4e-07 32.0 0.0 1.9e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEG38648.1 - 6.7e-07 29.9 0.0 9.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CEG38648.1 - 0.0033 17.2 0.1 0.0054 16.5 0.1 1.3 1 1 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 CEG38648.1 - 0.0072 15.8 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) TPR_12 PF13424.6 CEG38650.1 - 2.2e-08 34.3 1.4 0.005 17.1 0.1 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG38650.1 - 2.6e-06 27.2 3.2 0.04 14.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG38650.1 - 5.1e-06 26.9 0.1 0.061 14.2 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG38650.1 - 1.1e-05 25.1 4.6 0.016 15.3 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG38650.1 - 1.9e-05 24.3 0.2 0.051 13.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG38650.1 - 2.4e-05 23.9 3.4 0.021 14.6 0.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG38650.1 - 3.5e-05 23.5 1.4 0.13 12.3 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG38650.1 - 5.2e-05 23.6 0.3 0.32 11.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CEG38650.1 - 0.00017 21.6 1.9 0.068 13.3 0.1 2.8 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain SNAP PF14938.6 CEG38650.1 - 0.0094 15.4 6.0 0.26 10.7 0.4 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP ANAPC5 PF12862.7 CEG38650.1 - 0.015 15.4 0.6 0.47 10.6 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF2225 PF09986.9 CEG38650.1 - 0.028 14.1 2.4 0.15 11.8 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FTCD PF02971.14 CEG38650.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Formiminotransferase domain NSF PF02071.20 CEG38650.1 - 0.52 11.3 3.9 16 6.9 0.1 3.6 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat HSR PF03172.13 CEG38651.1 - 0.03 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 HSR domain DUF389 PF04087.14 CEG38651.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF389) DUF5380 PF17351.2 CEG38653.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5380) Peptidase_S10 PF00450.22 CEG38654.1 - 3e-48 165.3 0.0 3.8e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3649 PF12365.8 CEG38654.1 - 1 9.1 4.0 0.28 11.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Zip PF02535.22 CEG38655.1 - 1.2e-29 103.6 9.7 6.8e-28 97.8 9.7 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 CEG38655.1 - 0.31 10.7 5.7 0.94 9.2 0.2 2.7 2 1 1 3 3 3 0 Cation efflux family Asp PF00026.23 CEG38656.1 - 3.8e-23 82.4 0.2 2.5e-22 79.7 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG38656.1 - 1.6e-20 74.1 1.7 3.1e-20 73.2 1.7 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG38656.1 - 8.3e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 CEG38656.1 - 0.0062 17.1 0.0 0.06 13.9 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEG38656.1 - 0.015 16.0 0.0 0.27 11.9 0.1 2.6 2 0 0 2 2 2 0 Aspartyl protease AlgF PF11182.8 CEG38656.1 - 0.095 12.5 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF DEAD PF00270.29 CEG38656.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase RNA_POL_M_15KD PF02150.16 CEG38657.1 - 1.7e-10 40.6 6.1 1.7e-10 40.6 6.1 2.5 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 CEG38657.1 - 4.6e-05 23.4 2.6 0.0055 16.7 1.6 2.3 2 0 0 2 2 2 1 Double zinc ribbon TFIIS_C PF01096.18 CEG38657.1 - 0.0017 18.2 5.2 0.044 13.6 0.2 3.2 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.6 CEG38657.1 - 0.0018 18.0 7.1 0.079 12.7 0.2 3.4 3 0 0 3 3 3 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEG38657.1 - 0.0019 17.5 7.0 0.14 11.6 0.3 3.4 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_10 PF10058.9 CEG38657.1 - 0.0044 16.7 6.3 0.12 12.1 1.1 2.6 2 1 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 CEG38657.1 - 0.0071 16.8 2.4 0.44 11.1 0.6 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf-RRN7 PF11781.8 CEG38657.1 - 0.0073 16.0 2.8 1.9 8.2 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_Tnp_IS1595 PF12760.7 CEG38657.1 - 0.0077 16.2 6.3 0.45 10.5 0.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CEG38657.1 - 0.011 15.9 5.1 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain CpXC PF14353.6 CEG38657.1 - 0.013 15.5 3.1 0.45 10.6 0.2 2.4 2 1 0 2 2 2 0 CpXC protein HypA PF01155.19 CEG38657.1 - 0.018 15.1 2.5 0.078 13.0 2.1 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ogr_Delta PF04606.12 CEG38657.1 - 0.029 14.3 0.5 0.83 9.7 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S27e PF01667.17 CEG38657.1 - 0.03 14.0 2.4 0.15 11.8 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein S27 DUF3268 PF11672.8 CEG38657.1 - 0.041 14.2 2.2 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zinc-ribbons_6 PF07191.12 CEG38657.1 - 0.14 12.2 3.5 1 9.4 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbons Cys_rich_CPXG PF14255.6 CEG38657.1 - 0.14 12.1 0.4 0.14 12.1 0.4 2.7 2 1 0 2 2 2 0 Cysteine-rich CPXCG zf-RING_7 PF02591.15 CEG38657.1 - 0.19 11.9 7.9 0.62 10.3 2.3 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain C1_1 PF00130.22 CEG38657.1 - 0.2 11.6 2.7 0.17 11.8 0.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1610 PF07754.11 CEG38657.1 - 0.21 11.6 4.9 2.5 8.1 1.8 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1610) A2L_zn_ribbon PF08792.10 CEG38657.1 - 0.22 11.3 5.9 11 5.9 0.0 3.6 3 1 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_4 PF13717.6 CEG38657.1 - 0.31 11.0 5.6 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 CEG38657.1 - 0.35 11.0 4.5 8.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DNA_RNApol_7kD PF03604.13 CEG38657.1 - 0.46 10.2 9.1 5 6.9 0.0 3.2 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-LITAF-like PF10601.9 CEG38657.1 - 0.62 10.4 0.1 0.62 10.4 0.1 2.9 2 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-IS66 PF13005.7 CEG38657.1 - 0.96 9.9 8.1 6.1 7.3 0.3 3.6 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 TF_Zn_Ribbon PF08271.12 CEG38657.1 - 1.4 8.5 9.2 7.5 6.2 0.2 3.2 2 1 0 2 2 2 0 TFIIB zinc-binding zf-ISL3 PF14690.6 CEG38657.1 - 3.2 8.5 8.9 20 5.9 0.8 3.2 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prim_Zn_Ribbon PF08273.12 CEG38657.1 - 4 7.8 12.8 14 6.1 4.5 3.6 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase OrfB_Zn_ribbon PF07282.11 CEG38657.1 - 7.4 6.6 8.7 12 5.9 2.0 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 CEG38657.1 - 9 6.5 8.7 9.7 6.4 0.3 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 NUDIX PF00293.28 CEG38658.1 - 4.5e-18 65.6 0.1 1.1e-17 64.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain NUDIX_2 PF13869.6 CEG38658.1 - 0.0007 19.2 0.2 0.0092 15.6 0.0 2.0 2 0 0 2 2 2 1 Nucleotide hydrolase C2 PF00168.30 CEG38659.1 - 2.1e-05 24.7 0.1 4.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain SnoaL_2 PF12680.7 CEG38659.1 - 0.033 14.8 0.0 0.098 13.3 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain DUF4440 PF14534.6 CEG38659.1 - 0.063 13.7 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) TPT PF03151.16 CEG38661.1 - 3.2e-59 200.7 21.8 4.1e-59 200.3 21.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UQ_con PF00179.26 CEG38661.1 - 4.1e-44 149.6 0.0 6.7e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EamA PF00892.20 CEG38661.1 - 2.1e-11 44.2 22.1 2.7e-07 30.8 6.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEG38661.1 - 2e-10 40.4 23.9 2.5e-10 40.0 23.9 1.1 1 0 0 1 1 1 1 UAA transporter family HeLo PF14479.6 CEG38661.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation TMEM234 PF10639.9 CEG38661.1 - 3.2 7.8 12.2 0.64 10.1 0.8 3.3 3 0 0 3 3 3 0 Putative transmembrane family 234 His_Phos_1 PF00300.22 CEG38662.1 - 3.2e-33 115.1 0.2 4e-30 105.0 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 CEG38662.1 - 0.12 12.7 0.2 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain PPR_2 PF13041.6 CEG38663.1 - 2.2e-06 27.7 1.3 0.098 12.9 0.1 3.5 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 CEG38663.1 - 0.00017 21.6 1.6 0.024 14.7 0.1 3.2 2 1 1 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CEG38663.1 - 0.0025 17.2 0.8 0.0049 16.3 0.3 1.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Cag12 PF13117.6 CEG38663.1 - 0.0034 17.9 1.0 1.6 9.3 0.1 2.3 2 0 0 2 2 2 2 Cag pathogenicity island protein Cag12 YqaH PF17448.2 CEG38663.1 - 0.0056 16.9 0.7 0.026 14.8 0.1 2.5 2 1 1 3 3 3 1 Uncharacterized YqaH-like TPR_7 PF13176.6 CEG38663.1 - 0.016 15.2 0.3 0.092 12.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG38663.1 - 0.018 15.2 1.1 0.078 13.2 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-S27 PF10037.9 CEG38663.1 - 0.023 13.6 0.1 0.023 13.6 0.1 2.4 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 PPR PF01535.20 CEG38663.1 - 0.049 13.9 0.1 0.57 10.5 0.0 2.7 3 0 0 3 3 3 0 PPR repeat Exog_C PF18026.1 CEG38663.1 - 0.069 13.2 1.5 1.1 9.4 0.2 2.8 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Astacin PF01400.24 CEG38665.1 - 1.2e-21 77.2 0.1 2.5e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) CbtA PF09490.10 CEG38665.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Carn_acyltransf PF00755.20 CEG38666.1 - 4.2e-185 616.8 0.0 4.7e-185 616.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SRP68 PF16969.5 CEG38668.1 - 2.1e-121 406.7 21.2 3.7e-121 405.9 21.2 1.4 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 CEG38668.1 - 0.086 13.0 4.6 0.64 10.3 1.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_PH PF01138.21 CEG38669.1 - 1.5e-34 119.3 0.0 2.1e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG38669.1 - 9e-08 32.0 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1797 PF08796.10 CEG38669.1 - 0.1 12.7 0.5 0.45 10.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Radical_SAM PF04055.21 CEG38670.1 - 4.3e-12 46.7 0.0 1.3e-11 45.2 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 CEG38670.1 - 5e-08 33.3 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family TMP-TENI PF02581.17 CEG38670.1 - 0.023 14.0 0.0 0.78 9.0 0.0 2.7 2 1 1 3 3 3 0 Thiamine monophosphate synthase Ribosomal_S7e PF01251.18 CEG38672.1 - 8.5e-67 224.5 0.6 9.2e-67 224.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RNase_PH PF01138.21 CEG38675.1 - 1e-31 110.2 0.0 1.4e-18 67.7 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG38675.1 - 3.5e-13 49.4 0.5 2.7e-08 33.7 0.1 2.9 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 CEG38675.1 - 2.4e-09 36.9 0.5 6.9e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 KH domain S1 PF00575.23 CEG38675.1 - 8.3e-09 35.7 0.1 3.1e-08 33.9 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain KH_2 PF07650.17 CEG38675.1 - 0.031 14.1 0.1 0.096 12.5 0.1 1.8 1 0 0 1 1 1 0 KH domain CSD PF00313.22 CEG38675.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain AvrE_T3Es PF11725.8 CEG38675.1 - 0.072 10.3 0.1 0.097 9.9 0.1 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) ChitinaseA_N PF08329.10 CEG38675.1 - 0.099 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain KH_5 PF13184.6 CEG38675.1 - 0.13 12.4 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 NusA-like KH domain RRM_1 PF00076.22 CEG38676.1 - 8.6e-26 89.6 0.0 1.5e-10 40.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG38676.1 - 0.00014 21.9 0.0 0.0007 19.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 CEG38676.1 - 0.0029 17.7 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 CEG38676.1 - 0.0052 16.8 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif DUF2457 PF10446.9 CEG38676.1 - 0.033 13.4 7.3 0.043 13.0 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4299 PF14132.6 CEG38676.1 - 0.22 10.9 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) Ribosomal_L38e PF01781.18 CEG38677.1 - 1.9e-33 114.4 3.1 2.2e-33 114.1 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Ank_2 PF12796.7 CEG38678.1 - 1.9e-95 313.6 34.8 2.4e-16 60.1 0.9 8.3 3 3 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG38678.1 - 3.4e-69 228.0 37.5 1.1e-08 35.1 0.3 15.4 8 5 7 15 15 15 14 Ankyrin repeats (many copies) Ank PF00023.30 CEG38678.1 - 4e-69 226.3 50.3 1.1e-08 35.2 0.1 15.7 17 0 0 17 17 17 13 Ankyrin repeat Ank_4 PF13637.6 CEG38678.1 - 4.4e-65 215.3 23.1 2.7e-12 46.9 0.1 12.7 7 5 8 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG38678.1 - 5.1e-57 183.1 30.1 2.5e-06 27.4 0.0 15.3 15 0 0 15 15 15 12 Ankyrin repeat VWA_3_C PF18571.1 CEG38678.1 - 0.85 9.5 3.2 27 4.7 0.0 4.7 6 1 1 7 7 7 0 von Willebrand factor type A C-terminal domain Cpn60_TCP1 PF00118.24 CEG38679.1 - 2.4e-140 468.5 9.8 2.8e-140 468.2 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Say1_Mug180 PF10340.9 CEG38680.1 - 0.076 11.9 0.1 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CEG38682.1 - 2e-12 46.9 0.0 2.9e-11 43.1 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG38682.1 - 4.9e-09 36.2 0.0 3.7e-07 30.0 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CEG38682.1 - 5.3e-09 36.1 0.1 6.2e-06 26.0 0.0 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 CEG38682.1 - 1.3e-05 24.0 0.0 0.0056 15.4 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 CEG38682.1 - 0.00012 22.8 0.0 0.00018 22.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CEG38682.1 - 0.00021 21.1 0.0 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CEG38682.1 - 0.00042 19.8 0.0 0.0029 17.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Armet PF10208.9 CEG38682.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding COX15-CtaA PF02628.15 CEG38683.1 - 2e-104 349.2 3.3 2.3e-104 349.0 3.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Spermine_synth PF01564.17 CEG38686.1 - 8.3e-69 230.8 0.4 1.4e-68 230.1 0.1 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CEG38686.1 - 1.6e-23 82.4 0.2 3.7e-23 81.2 0.2 1.7 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CEG38686.1 - 0.00087 19.9 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG38686.1 - 0.014 16.1 0.0 0.033 14.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CEG38686.1 - 0.017 16.1 0.0 0.042 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38686.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 CEG38686.1 - 0.037 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF166 PF02593.14 CEG38686.1 - 0.084 12.4 0.1 2.5 7.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function DREV PF05219.12 CEG38686.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Exo_endo_phos PF03372.23 CEG38688.1 - 4.1e-19 69.0 0.0 6.9e-18 65.0 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEG38688.1 - 0.0062 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Tri3 PF07428.11 CEG38688.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Ribosomal_L32e PF01655.18 CEG38689.1 - 1e-44 151.4 0.6 1.3e-44 151.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Esterase PF00756.20 CEG38691.1 - 1.4e-05 24.8 1.9 0.0001 22.0 1.9 2.0 1 1 0 1 1 1 1 Putative esterase PhoLip_ATPase_C PF16212.5 CEG38692.1 - 3.5e-67 226.8 9.4 3.5e-67 226.8 9.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG38692.1 - 1.5e-18 66.2 0.7 3.6e-18 65.0 0.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG38692.1 - 4.8e-10 40.1 0.5 0.0046 17.3 0.7 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG38692.1 - 6e-09 35.9 0.0 2.3e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG38692.1 - 9.6e-06 25.2 0.0 3.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG38692.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGM_PMM_I PF02878.16 CEG38692.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DCP1 PF06058.13 CEG38694.1 - 3.9e-36 123.5 0.2 6.7e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 CEG38694.1 - 4.2e-07 29.1 0.0 9.1e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus HhH-GPD PF00730.25 CEG38695.1 - 1.2e-20 74.0 0.0 2.7e-20 72.8 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEG38695.1 - 0.001 18.8 0.1 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CEG38695.1 - 0.0041 17.4 8.1 0.0079 16.5 8.1 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III DUF2067 PF09840.9 CEG38695.1 - 0.01 15.5 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Kelch_3 PF13415.6 CEG38697.1 - 9.5e-24 83.2 13.4 3.8e-08 33.4 0.1 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG38697.1 - 5.3e-21 74.2 0.6 0.00023 21.1 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CEG38697.1 - 1.6e-17 63.1 3.4 0.00077 19.7 0.1 6.1 5 1 1 6 6 6 4 Kelch motif TPR_1 PF00515.28 CEG38697.1 - 2.6e-17 61.8 3.4 1.3e-07 31.1 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat Kelch_4 PF13418.6 CEG38697.1 - 6.5e-17 61.3 5.3 0.012 15.6 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain TPR_2 PF07719.17 CEG38697.1 - 1.6e-15 55.9 1.1 0.00022 21.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat Kelch_2 PF07646.15 CEG38697.1 - 3.9e-12 45.6 4.7 0.00094 19.1 0.0 6.4 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 CEG38697.1 - 1.4e-11 43.7 5.0 0.015 14.8 0.0 6.2 6 1 0 6 6 6 4 Kelch motif TPR_8 PF13181.6 CEG38697.1 - 5.7e-09 35.5 0.0 0.17 12.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG38697.1 - 6.9e-08 32.1 0.5 0.00024 20.7 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 CEG38697.1 - 3.4e-05 23.9 2.5 9.2e-05 22.6 0.7 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG38697.1 - 9.3e-05 23.0 0.1 0.43 11.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG38697.1 - 0.0007 19.7 3.9 0.45 10.7 0.9 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG38697.1 - 0.0026 17.8 1.0 0.46 10.6 0.1 2.7 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEG38697.1 - 0.0033 17.3 0.1 1.6 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG38697.1 - 0.0084 16.6 1.9 0.079 13.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG38697.1 - 0.024 14.9 2.9 0.19 12.1 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG38697.1 - 0.096 12.6 3.1 0.25 11.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG38697.1 - 0.18 12.1 1.0 0.39 11.0 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CEG38697.1 - 0.4 11.6 1.6 44 5.3 0.6 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Hydrolase PF00702.26 CEG38698.1 - 2e-06 28.2 0.1 4.2e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG38698.1 - 2.9e-06 27.8 0.2 1.7e-05 25.3 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CEG38698.1 - 0.011 15.2 3.0 1.5 8.1 0.4 2.7 1 1 0 2 2 2 0 Putative Phosphatase YqgF PF14639.6 CEG38698.1 - 0.051 13.4 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 OTU PF02338.19 CEG38699.1 - 3.9e-21 75.9 1.0 6.3e-20 72.0 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEG38699.1 - 4.6e-05 23.0 0.2 0.017 14.6 0.0 2.5 1 1 1 3 3 3 2 Peptidase C65 Otubain AAA_17 PF13207.6 CEG38699.1 - 5 7.5 12.9 4.3 7.8 8.7 2.2 1 1 1 2 2 2 0 AAA domain DcpS_C PF11969.8 CEG38702.1 - 6.2e-26 91.1 0.1 7.7e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEG38702.1 - 9e-12 45.6 3.5 2.9e-11 44.0 3.5 1.7 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 CEG38702.1 - 4.1e-06 26.7 0.1 5.5e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 NUC153 PF08159.12 CEG38704.1 - 3.3e-08 33.2 0.3 3.3e-08 33.2 0.3 3.9 4 0 0 4 4 4 3 NUC153 domain BBIP10 PF14777.6 CEG38705.1 - 5.5e-20 70.7 0.1 6.1e-20 70.6 0.1 1.1 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 DUF410 PF04190.13 CEG38706.1 - 4.4e-64 216.7 0.8 5.6e-64 216.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 CEG38706.1 - 0.16 12.2 1.1 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Complex1_LYR PF05347.15 CEG38707.1 - 1.2e-09 38.0 0.1 2.2e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEG38707.1 - 0.017 15.9 0.4 0.039 14.7 0.4 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Ammonium_transp PF00909.21 CEG38709.1 - 7e-56 189.6 7.5 8.9e-56 189.3 7.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Claudin_3 PF06653.11 CEG38709.1 - 0.017 15.1 1.1 0.07 13.1 0.0 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like UNC-79 PF14776.6 CEG38709.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 UPF0154 PF03672.13 CEG38709.1 - 0.17 11.9 3.0 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) E1_4HB PF16191.5 CEG38710.1 - 0.089 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 CEG38712.1 - 9.5e-64 215.3 0.0 1.4e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38712.1 - 4.5e-34 117.9 0.0 7.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG38712.1 - 6.3e-07 29.0 0.0 7.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CEG38712.1 - 0.00015 20.9 0.1 0.00027 20.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CEG38712.1 - 0.00059 18.9 0.0 0.00059 18.9 0.0 2.2 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 CEG38712.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEG38712.1 - 0.019 14.6 0.2 0.96 9.0 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEG38712.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEG38712.1 - 0.11 12.0 0.7 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pro_isomerase PF00160.21 CEG38713.1 - 5.3e-52 176.3 0.1 1.3e-51 175.0 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CEG38713.1 - 5.1e-08 32.6 1.6 1.2e-07 31.3 1.6 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CEG38713.1 - 1.5e-05 25.0 0.2 4.8e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Arm PF00514.23 CEG38714.1 - 1.7e-13 50.1 22.9 0.0034 17.4 0.1 7.4 7 1 1 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CEG38714.1 - 6.4e-06 26.0 1.5 0.26 11.7 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CEG38714.1 - 0.00051 20.4 11.2 0.33 11.4 0.6 4.1 1 1 4 5 5 5 4 HEAT repeats Arm_2 PF04826.13 CEG38714.1 - 0.001 18.6 5.9 0.039 13.4 0.1 3.1 2 1 1 3 3 3 3 Armadillo-like RICTOR_V PF14668.6 CEG38714.1 - 0.037 14.3 0.4 1.7 9.0 0.0 3.1 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 CEG38714.1 - 8 7.1 13.9 1.1 9.8 1.6 4.1 3 2 2 5 5 5 0 HEAT-like repeat GlcNAc PF11397.8 CEG38715.1 - 2.1e-49 168.9 0.1 9e-40 137.2 0.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) FAM220 PF15487.6 CEG38715.1 - 0.18 11.4 0.9 11 5.6 0.2 2.3 2 0 0 2 2 2 0 FAM220 family DUF4729 PF15866.5 CEG38716.1 - 0.029 13.7 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) B56 PF01603.20 CEG38717.1 - 1.6e-89 300.8 0.1 2.1e-89 300.4 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 CEG38717.1 - 1.2e-18 67.5 0.0 2.5e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 CEG38718.1 - 6.8e-30 104.3 0.0 4e-27 95.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain PP2C PF00481.21 CEG38718.1 - 4.1e-16 59.4 0.0 3.2e-15 56.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 CEG38718.1 - 1.8e-10 40.6 0.0 6.1e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_4 PF13894.6 CEG38718.1 - 0.012 16.3 5.5 0.094 13.6 3.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Kdo PF06293.14 CEG38718.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG38718.1 - 0.038 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CEG38718.1 - 0.058 13.9 4.6 0.43 11.1 2.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CEG38718.1 - 0.084 13.2 1.6 0.52 10.7 2.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Spore_III_AB PF09548.10 CEG38718.1 - 0.11 12.7 0.0 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Zn_Tnp_IS1595 PF12760.7 CEG38718.1 - 0.12 12.4 0.3 0.39 10.7 0.3 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain XTBD PF11952.8 CEG38718.1 - 0.17 11.7 0.8 15 5.4 0.0 2.9 3 0 0 3 3 3 0 XRN-Two Binding Domain, XTBD zf-C2H2_jaz PF12171.8 CEG38718.1 - 0.89 9.9 3.8 0.46 10.8 1.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UBP PF02148.19 CEG38718.1 - 3.4 8.1 5.6 0.6 10.5 1.3 2.0 2 0 0 2 2 1 0 Zn-finger in ubiquitin-hydrolases and other protein tRNA-synt_1c PF00749.21 CEG38720.1 - 0.15 11.0 0.0 0.3 9.9 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain GH131_N PF18271.1 CEG38723.1 - 7.2e-39 134.0 0.0 9.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Peptidase_M10_C PF08548.11 CEG38724.1 - 0.054 13.4 0.3 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase M10 serralysin C terminal TEX33 PF15400.6 CEG38724.1 - 5.1 7.6 10.9 0.065 13.7 1.6 2.6 3 1 1 4 4 4 0 Testis-expressed sequence 33 protein family AMP-binding PF00501.28 CEG38725.1 - 3.9e-76 256.3 0.0 5.3e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CEG38725.1 - 9.4e-11 41.9 0.1 1.1e-09 38.5 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 CEG38725.1 - 0.00025 21.3 0.0 0.00084 19.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FYVE PF01363.21 CEG38726.1 - 5.7e-13 48.8 5.1 1.3e-12 47.6 5.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG38726.1 - 5.6 7.2 9.9 0.044 14.0 0.9 2.0 3 0 0 3 3 3 0 FYVE-type zinc finger MMR_HSR1 PF01926.23 CEG38727.1 - 3e-53 178.8 0.3 3e-26 91.7 0.0 2.9 3 1 1 4 4 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG38727.1 - 1.5e-25 89.6 0.0 8.3e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 CEG38727.1 - 2.9e-16 59.5 0.6 2.1e-14 53.6 0.4 2.6 1 1 1 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 CEG38727.1 - 2.5e-12 46.8 0.1 0.00039 20.0 0.3 4.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CEG38727.1 - 4.4e-12 45.8 0.1 7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 CEG38727.1 - 2.6e-11 43.9 1.2 0.011 15.8 0.1 4.4 3 1 1 4 4 4 3 Dynamin family Ras PF00071.22 CEG38727.1 - 1.4e-10 41.0 0.0 0.00039 20.1 0.0 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CEG38727.1 - 8.2e-09 35.7 0.0 0.007 16.6 0.0 3.7 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CEG38727.1 - 8.1e-08 32.4 0.2 0.0088 16.0 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase Arf PF00025.21 CEG38727.1 - 1e-07 31.6 0.2 0.11 11.9 0.0 3.3 3 0 0 3 3 3 2 ADP-ribosylation factor family SRPRB PF09439.10 CEG38727.1 - 3.2e-07 30.0 0.0 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 CEG38727.1 - 6.7e-06 25.5 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 CEG38727.1 - 6.8e-06 26.6 0.0 0.19 12.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 CEG38727.1 - 0.0001 21.8 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 CEG38727.1 - 0.00093 19.5 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 CEG38727.1 - 0.0013 18.6 0.1 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 CEG38727.1 - 0.0019 18.7 0.0 3.3 8.3 0.0 3.2 2 2 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 CEG38727.1 - 0.0033 17.8 0.0 3.6 8.0 0.0 2.7 2 1 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 CEG38727.1 - 0.0039 16.9 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 CEG38727.1 - 0.0045 16.7 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CEG38727.1 - 0.0095 15.9 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Septin PF00735.18 CEG38727.1 - 0.01 15.1 0.0 3.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Septin MobB PF03205.14 CEG38727.1 - 0.012 15.6 1.5 6.2 6.7 0.0 3.5 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 CEG38727.1 - 0.023 13.7 0.2 2.9 6.8 0.0 3.2 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 CEG38727.1 - 0.038 14.0 0.3 5.6 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain HisKA_3 PF07730.13 CEG38727.1 - 0.039 14.5 0.3 0.11 13.0 0.0 2.0 2 0 0 2 2 1 0 Histidine kinase G-alpha PF00503.20 CEG38727.1 - 0.049 12.8 0.0 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 CEG38727.1 - 0.11 12.7 0.0 25 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG38727.1 - 0.12 12.7 0.1 24 5.2 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain DAP3 PF10236.9 CEG38727.1 - 0.12 11.5 0.0 9.8 5.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 GBP PF02263.19 CEG38727.1 - 0.15 11.3 0.0 4.6 6.4 0.0 2.3 2 1 0 2 2 2 0 Guanylate-binding protein, N-terminal domain PduV-EutP PF10662.9 CEG38727.1 - 0.2 11.4 0.0 3.5 7.4 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-met2 PF12907.7 CEG38728.1 - 9.1e-23 80.1 11.5 2.5e-13 49.9 1.6 4.0 4 0 0 4 4 4 2 Zinc-binding zf-BED PF02892.15 CEG38728.1 - 3.7e-05 23.6 7.7 0.026 14.6 0.7 2.5 2 0 0 2 2 2 2 BED zinc finger Eapp_C PF10238.9 CEG38728.1 - 6.3e-05 23.1 7.5 0.06 13.4 0.2 2.2 2 0 0 2 2 2 2 E2F-associated phosphoprotein Sin3a_C PF16879.5 CEG38728.1 - 0.0047 16.7 7.0 0.48 10.1 0.2 2.2 2 0 0 2 2 2 2 C-terminal domain of Sin3a protein PPR_3 PF13812.6 CEG38728.1 - 0.018 15.1 0.1 4.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain zf-C2H2_4 PF13894.6 CEG38728.1 - 0.018 15.8 4.2 4.5 8.4 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger MafB19-deam PF14437.6 CEG38728.1 - 0.027 14.2 3.8 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 MafB19-like deaminase FYVE PF01363.21 CEG38728.1 - 0.035 14.2 0.9 6.8 6.9 0.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger LUC7 PF03194.15 CEG38728.1 - 0.049 13.3 15.0 0.56 9.8 2.7 2.1 2 0 0 2 2 2 0 LUC7 N_terminus OrsD PF12013.8 CEG38728.1 - 0.6 10.6 4.4 12 6.4 0.4 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Peroxin-13_N PF04088.13 CEG38728.1 - 0.67 10.2 4.2 5.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region EMC3_TMCO1 PF01956.16 CEG38728.1 - 0.89 9.3 9.5 3.1 7.5 0.8 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Nuc_N PF14448.6 CEG38728.1 - 2.3 8.1 6.9 17 5.4 0.7 2.6 2 0 0 2 2 2 0 Nuclease N terminal DUF4834 PF16118.5 CEG38728.1 - 4.6 8.3 9.8 2.4 9.2 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) zf-met PF12874.7 CEG38728.1 - 7.8 7.0 15.4 3 8.4 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Fer4_16 PF13484.6 CEG38728.1 - 9.8 7.2 13.3 13 6.8 2.4 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Spt20 PF12090.8 CEG38728.1 - 9.9 5.7 12.5 6.7 6.3 2.3 2.1 1 1 0 2 2 2 0 Spt20 family Filament PF00038.21 CEG38729.1 - 0.0022 17.6 52.2 0.0022 17.6 52.2 4.4 1 1 2 3 3 3 1 Intermediate filament protein WD40_alt PF14077.6 CEG38729.1 - 0.031 14.1 4.2 9 6.2 0.0 4.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif ACT_5 PF13710.6 CEG38729.1 - 0.086 12.7 0.9 6.4 6.7 0.0 3.0 2 0 0 2 2 2 0 ACT domain DUF4407 PF14362.6 CEG38729.1 - 0.21 10.9 56.9 1.1 8.5 16.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CEG38729.1 - 0.23 10.3 75.3 1.6 7.6 24.2 4.4 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 CEG38729.1 - 0.43 10.7 75.6 1.3 9.1 18.4 5.2 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding IFT57 PF10498.9 CEG38729.1 - 0.53 9.2 67.0 0.35 9.8 17.0 3.8 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 GAS PF13851.6 CEG38729.1 - 1.7 8.0 80.1 0.1 11.9 17.2 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CEG38730.1 - 0.00088 19.4 4.3 0.00088 19.4 4.3 9.3 10 2 2 12 12 12 3 Homeobox associated leucine zipper bZIP_1 PF00170.21 CEG38730.1 - 0.029 14.5 1.0 0.029 14.5 1.0 8.7 8 1 1 9 9 9 0 bZIP transcription factor SnoaL PF07366.12 CEG38731.1 - 1.3e-05 25.0 0.0 3.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Exo_endo_phos PF03372.23 CEG38734.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ERCC3_RAD25_C PF16203.5 CEG38735.1 - 1.4e-108 361.8 0.0 2.3e-108 361.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CEG38735.1 - 1.4e-34 119.0 0.0 2.9e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG38735.1 - 2.2e-14 53.8 0.0 9.7e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEG38735.1 - 4.3e-10 39.9 0.0 1.2e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CEG38735.1 - 6e-06 25.2 0.0 8.8e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain TauD PF02668.16 CEG38735.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family RNA_bind PF08675.11 CEG38737.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Gp_dh_C PF02800.20 CEG38738.1 - 5.1e-34 117.1 0.0 9.3e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEG38738.1 - 3.7e-19 68.9 0.1 2.7e-18 66.1 0.0 2.4 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ras PF00071.22 CEG38740.1 - 1.3e-64 216.7 1.0 1.5e-64 216.5 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG38740.1 - 1.1e-34 119.2 1.0 1.3e-34 118.9 0.3 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG38740.1 - 4.1e-17 62.2 0.3 5.2e-17 61.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEG38740.1 - 3.5e-07 30.0 0.4 5.4e-07 29.3 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEG38740.1 - 1.2e-05 24.8 0.4 1.7e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG38740.1 - 8.3e-05 22.6 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG38740.1 - 9.9e-05 22.4 0.1 0.00021 21.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CEG38740.1 - 0.0088 15.8 0.3 0.12 12.2 0.3 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CEG38740.1 - 0.017 14.7 0.1 0.095 12.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 CEG38740.1 - 0.078 13.3 0.1 0.32 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG38740.1 - 0.079 13.3 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEG38740.1 - 0.11 12.2 0.5 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Methyltransf_25 PF13649.6 CEG38741.1 - 1.1e-10 42.0 0.1 2.8e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38741.1 - 9.9e-10 38.4 0.2 6.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CEG38741.1 - 1.2e-09 38.0 0.4 2.5e-09 37.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CEG38741.1 - 6.4e-08 33.1 0.1 1.7e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG38741.1 - 1.9e-06 27.4 0.0 4.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CEG38741.1 - 3.9e-06 26.8 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEG38741.1 - 4e-05 22.7 0.3 7e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CEG38741.1 - 0.00094 19.9 0.0 0.0025 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CEG38741.1 - 0.0011 19.1 0.1 0.0021 18.2 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 CEG38741.1 - 0.002 17.7 0.3 0.0035 16.9 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FRQ PF09421.10 CEG38741.1 - 0.01 13.9 1.0 0.015 13.4 1.0 1.1 1 0 0 1 1 1 0 Frequency clock protein Methyltransf_18 PF12847.7 CEG38741.1 - 0.012 15.6 0.3 0.024 14.6 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CEG38741.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CEG38741.1 - 0.023 14.4 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 CEG38741.1 - 0.028 14.2 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CEG38741.1 - 0.046 13.7 0.3 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain zf-C2H2_2 PF12756.7 CEG38741.1 - 0.067 13.5 2.0 0.35 11.2 0.4 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF5344 PF17279.2 CEG38741.1 - 0.074 13.6 0.4 0.16 12.6 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5344) TehB PF03848.14 CEG38741.1 - 0.2 11.0 1.7 0.29 10.5 0.2 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TehB RAB3GAP2_N PF14655.6 CEG38742.1 - 7.9e-58 196.7 0.0 1.6e-57 195.7 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 CEG38742.1 - 2.1e-13 49.4 4.9 1.5e-09 36.7 0.2 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF150_C PF17384.2 CEG38742.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RimP C-terminal SH3 domain N6-adenineMlase PF10237.9 CEG38744.1 - 2.8e-40 137.7 1.1 3.2e-40 137.5 1.1 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase N6-adenineMlase PF10237.9 CEG38745.1 - 7.4e-43 146.1 0.9 9.4e-43 145.8 0.9 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 CEG38745.1 - 0.094 12.3 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 FYVE PF01363.21 CEG38746.1 - 4.6e-15 55.5 14.5 1.3e-14 54.0 14.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG38746.1 - 0.0022 18.2 7.2 0.0045 17.2 6.1 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Sec63 PF02889.16 CEG38747.1 - 1.5e-39 135.7 0.1 2.2e-39 135.2 0.1 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 CEG38747.1 - 3.5e-21 75.1 0.1 8.5e-21 73.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain EI24 PF07264.11 CEG38747.1 - 0.027 14.7 0.0 0.075 13.3 0.0 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4506 PF14958.6 CEG38748.1 - 1e-06 28.3 0.6 1.1e-05 25.0 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4506) DUF3552 PF12072.8 CEG38748.1 - 0.038 13.4 3.4 0.057 12.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RVT_2 PF07727.14 CEG38750.1 - 4e-17 62.7 0.1 5.5e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 CEG38750.1 - 0.043 13.5 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Cellulase PF00150.18 CEG38751.1 - 2e-25 89.8 0.3 2.6e-25 89.4 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TIG PF01833.24 CEG38751.1 - 0.086 12.9 0.4 2.1 8.5 0.0 3.0 3 0 0 3 3 3 0 IPT/TIG domain Cellulase PF00150.18 CEG38752.1 - 1.1e-43 149.7 6.7 2e-21 76.7 0.3 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Trp_oprn_chp PF09534.10 CEG38752.1 - 0.0063 16.3 0.1 2 8.2 0.0 2.6 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4307 PF14155.6 CEG38752.1 - 0.011 15.6 0.1 14 5.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4307) DUF2661 PF10860.8 CEG38752.1 - 0.13 12.4 0.1 8 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) TPPK_C PF12555.8 CEG38752.1 - 0.15 12.2 5.4 0.35 10.9 0.6 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Aminotran_5 PF00266.19 CEG38753.1 - 3.1e-41 141.6 0.0 5.1e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 CEG38753.1 - 6.2e-16 58.7 0.0 4.7e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 PP-loop family DUF2280 PF10045.9 CEG38753.1 - 0.15 12.4 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Tet_JBP PF12851.7 CEG38755.1 - 0.019 14.3 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Dynactin_p22 PF07426.11 CEG38755.1 - 0.021 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 RVT_2 PF07727.14 CEG38756.1 - 2.1e-08 34.1 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-gua_PtransN PF02807.15 CEG38757.1 - 1.8e-09 37.8 0.0 3.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Consortin_C PF15281.6 CEG38757.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus WD40 PF00400.32 CEG38758.1 - 4.7e-46 153.8 23.9 5e-09 36.7 0.1 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38758.1 - 1.3e-20 73.5 5.0 0.0016 18.7 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG38758.1 - 2.5e-08 34.0 0.8 8.3e-05 22.5 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CEG38758.1 - 4.2e-06 25.1 10.6 0.00039 18.6 10.6 2.3 1 1 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 CEG38758.1 - 9.6e-06 24.8 8.8 0.0089 15.0 0.2 4.8 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CEG38758.1 - 0.0039 17.0 3.7 0.0046 16.8 0.7 2.5 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain BiPBP_C PF06832.12 CEG38758.1 - 0.01 15.8 0.6 2 8.5 0.0 3.8 2 2 2 4 4 4 0 Penicillin-Binding Protein C-terminus Family DUF2387 PF09526.10 CEG38758.1 - 0.017 15.3 1.0 4.5 7.5 0.1 3.4 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Nbas_N PF15492.6 CEG38758.1 - 0.019 14.3 3.7 4.7 6.4 0.0 3.8 2 2 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 CEG38758.1 - 0.083 11.9 4.2 1.2 8.0 0.1 3.2 1 1 2 3 3 3 0 Coatomer WD associated region PD40 PF07676.12 CEG38758.1 - 0.094 12.7 2.9 0.95 9.5 0.2 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Homeodomain PF00046.29 CEG38759.1 - 0.00023 20.9 8.7 0.087 12.7 4.4 3.1 2 1 0 2 2 2 2 Homeodomain Hydrolase PF00702.26 CEG38759.1 - 0.05 13.9 0.1 0.44 10.8 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Tli4_C PF18426.1 CEG38759.1 - 0.13 12.6 1.8 0.52 10.6 0.1 2.5 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain CRISPR_Cse2 PF09485.10 CEG38759.1 - 0.21 12.1 0.1 0.21 12.1 0.1 3.3 3 1 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Homez PF11569.8 CEG38759.1 - 0.36 10.3 2.7 6.6 6.3 0.0 3.4 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez NuA4 PF09340.10 CEG38760.1 - 3.6e-05 23.5 0.7 0.00022 21.0 0.7 2.2 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CCDC73 PF15818.5 CEG38760.1 - 0.0048 14.8 0.2 0.0068 14.3 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 73 family Acyltransferase PF01553.21 CEG38761.1 - 3e-17 62.5 0.0 7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 CEG38763.1 - 3.7e-31 106.7 8.2 1.8e-08 34.9 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Striatin PF08232.12 CEG38763.1 - 2.5e-16 60.6 3.5 4e-16 60.0 3.3 1.5 1 1 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 CEG38763.1 - 1.1e-09 38.5 0.0 0.02 15.2 0.0 5.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEG38763.1 - 0.00052 18.9 0.0 1.6 7.4 0.0 3.3 2 1 2 4 4 4 2 Nup133 N terminal like DUF3450 PF11932.8 CEG38763.1 - 0.0025 17.2 4.5 0.0043 16.4 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HALZ PF02183.18 CEG38763.1 - 0.041 14.1 0.4 0.076 13.3 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 CEG38763.1 - 0.85 9.8 7.3 0.11 12.7 2.7 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 CEG38763.1 - 2.9 6.7 7.6 0.24 10.3 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) VPS13 PF16908.5 CEG38764.1 - 2.8e-65 220.4 7.6 2.8e-65 220.4 7.6 2.1 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 CEG38764.1 - 5.9e-44 150.3 0.0 6.1e-37 127.3 0.0 5.3 4 1 0 4 4 4 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 CEG38764.1 - 6.2e-36 123.8 0.3 8.3e-35 120.2 0.0 2.4 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CEG38764.1 - 8.6e-36 123.7 0.0 1.9e-29 102.9 0.0 4.2 4 0 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 CEG38764.1 - 4.3e-23 81.6 0.0 1.7e-22 79.7 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Apt1 PF10351.9 CEG38764.1 - 9.7e-05 21.4 0.1 0.00023 20.2 0.1 1.6 1 0 0 1 1 1 1 Golgi-body localisation protein domain ATG_C PF09333.11 CEG38764.1 - 0.082 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain ABC_tran PF00005.27 CEG38765.1 - 1.6e-33 116.1 0.0 3.3e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CEG38765.1 - 1.1e-24 87.6 4.3 1.9e-24 86.7 4.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CEG38765.1 - 1.9e-08 34.0 0.0 1.1e-06 28.3 0.0 2.3 2 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEG38765.1 - 0.00077 19.8 0.8 0.012 15.9 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG38765.1 - 0.0062 16.9 0.2 0.029 14.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEG38765.1 - 0.025 14.6 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CEG38765.1 - 0.031 14.2 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 CEG38765.1 - 0.032 13.9 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEG38765.1 - 0.035 13.7 0.1 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEG38765.1 - 0.037 13.8 0.4 0.17 11.6 0.2 2.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 CEG38765.1 - 0.041 13.6 0.8 0.24 11.1 0.8 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 CEG38765.1 - 0.051 13.2 0.2 0.15 11.7 0.2 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 CEG38765.1 - 0.07 11.9 0.3 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 CEG38765.1 - 0.07 13.6 0.3 0.76 10.2 0.3 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEG38765.1 - 0.097 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CEG38765.1 - 0.1 12.6 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CEG38765.1 - 0.11 12.2 0.3 0.35 10.6 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG38765.1 - 0.96 9.9 6.5 0.11 12.9 0.5 2.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CEG38765.1 - 3 7.9 6.4 0.65 10.0 0.1 2.9 3 1 1 4 4 4 0 Helicase HerA, central domain Trypsin PF00089.26 CEG38767.1 - 2.5e-47 161.5 0.0 4.2e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CEG38768.1 - 6.6e-49 166.7 0.0 7.7e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG38768.1 - 1.4e-06 29.3 0.0 2.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain CAP PF00188.26 CEG38769.1 - 4.3e-24 85.8 2.4 6.1e-24 85.3 2.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIIC_delta PF12657.7 CEG38770.1 - 2.3e-14 53.7 0.1 3e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 CEG38770.1 - 2.4e-06 27.4 2.0 6.1e-06 26.1 2.0 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.32 CEG38770.1 - 0.0023 18.7 7.4 0.023 15.5 0.2 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PKD_channel PF08016.12 CEG38771.1 - 3.2e-24 85.4 14.2 1.3e-17 63.6 16.8 3.3 2 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 CEG38771.1 - 2.1e-09 37.0 15.2 2.1e-09 37.0 15.2 1.8 2 0 0 2 2 2 1 Ion transport protein Asp_protease_2 PF13650.6 CEG38774.1 - 0.0078 16.8 0.1 0.015 15.9 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease MMADHC PF10229.9 CEG38774.1 - 0.015 15.0 2.0 0.02 14.7 2.0 1.1 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein gag-asp_proteas PF13975.6 CEG38774.1 - 0.035 14.6 0.2 0.069 13.7 0.2 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2452 PF10504.9 CEG38774.1 - 0.053 13.0 3.3 0.1 12.1 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) EMP24_GP25L PF01105.24 CEG38774.1 - 5 7.0 7.9 6.3 6.7 7.9 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RVT_1 PF00078.27 CEG38775.1 - 0.00093 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_lysis PF03245.13 CEG38775.1 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein WD40 PF00400.32 CEG38776.1 - 4.1e-14 52.8 14.2 0.00028 21.6 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ PF01011.21 CEG38776.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_3 PF13570.6 CEG38776.1 - 0.03 14.8 0.8 0.37 11.3 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 CEG38776.1 - 0.047 14.0 0.1 26 5.2 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_2 PF13532.6 CEG38777.1 - 5.9e-19 69.0 0.0 1.1e-18 68.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 CEG38777.1 - 7.1e-15 55.4 0.1 1.6e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG38777.1 - 5.1e-13 49.6 0.1 1.2e-12 48.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG38777.1 - 4.2e-06 26.6 0.0 8.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG38777.1 - 8.4e-06 26.5 0.1 1.8e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEG38777.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 CEG38777.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 CEG38777.1 - 0.0045 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEG38777.1 - 0.032 14.1 0.0 0.084 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CEG38777.1 - 0.036 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SMK-1 PF04802.15 CEG38778.1 - 2.1e-34 119.0 0.2 3.9e-34 118.1 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF1765 PF08578.10 CEG38778.1 - 0.67 10.4 3.9 1.1 9.7 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) HTH_38 PF13936.6 CEG38779.1 - 1.7e-05 24.5 0.4 6.1e-05 22.7 0.4 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEG38779.1 - 0.00019 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 CEG38779.1 - 0.0061 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 CEG38779.1 - 0.013 15.4 0.5 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 HTH domain HTH_7 PF02796.15 CEG38779.1 - 0.017 15.2 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Rrf2 PF02082.20 CEG38779.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_Tnp_ISL3 PF13542.6 CEG38779.1 - 0.17 11.3 0.1 0.75 9.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TatD_DNase PF01026.21 CEG38780.1 - 5e-37 127.7 0.0 6.2e-23 81.5 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase Lipase_3 PF01764.25 CEG38782.1 - 1.6e-11 44.3 0.0 3.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DFP PF04127.15 CEG38782.1 - 0.00015 21.6 0.9 0.0048 16.7 0.1 3.0 3 1 0 3 3 3 1 DNA / pantothenate metabolism flavoprotein PE-PPE PF08237.11 CEG38782.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 CEG38782.1 - 0.005 17.5 0.0 0.035 14.7 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.32 CEG38783.1 - 2.2e-15 56.8 12.1 1.8e-06 28.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG38783.1 - 0.0039 17.4 0.6 13 6.2 0.0 3.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 CEG38783.1 - 0.025 13.3 0.0 0.052 12.3 0.0 1.6 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal PQQ_2 PF13360.6 CEG38783.1 - 0.039 13.5 0.3 0.12 11.9 0.0 1.9 2 1 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 CEG38783.1 - 0.041 13.2 0.0 15 4.8 0.0 3.2 3 1 1 4 4 4 0 WD40-like domain SBDS_C PF09377.10 CEG38784.1 - 5.7e-30 103.7 1.3 1.2e-29 102.7 1.3 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CEG38784.1 - 8.7e-28 96.2 0.3 1.7e-27 95.3 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Syndecan PF01034.20 CEG38786.1 - 1 9.3 3.1 2 8.4 3.1 1.4 1 0 0 1 1 1 0 Syndecan domain Torsin PF06309.11 CEG38787.1 - 0.092 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Torsin Bap31 PF05529.12 CEG38790.1 - 8.2e-07 29.0 1.3 9.7e-07 28.7 1.3 1.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region BT1 PF03092.16 CEG38791.1 - 4.1e-17 61.6 17.0 3.5e-08 32.1 0.2 3.2 3 0 0 3 3 3 3 BT1 family TIM21 PF08294.11 CEG38791.1 - 3.6e-13 49.6 0.0 8.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CEG38791.1 - 0.049 13.4 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Dynein_AAA_lid PF17852.1 CEG38791.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain DUF5353 PF17304.2 CEG38791.1 - 0.29 10.9 10.2 1.8 8.4 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5353) SieB PF14163.6 CEG38791.1 - 1.1 8.8 3.8 3.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Super-infection exclusion protein B Glyco_hydro_47 PF01532.20 CEG38792.1 - 3.2e-138 461.5 0.8 4.5e-138 461.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IFRD PF05004.13 CEG38793.1 - 4.8e-43 147.4 5.4 6.5e-43 147.0 5.4 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Rif1_N PF12231.8 CEG38793.1 - 0.0012 18.0 0.1 0.015 14.3 0.0 2.1 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Vac14_Fab1_bd PF12755.7 CEG38793.1 - 0.036 14.6 0.2 0.17 12.5 0.1 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Carn_acyltransf PF00755.20 CEG38794.1 - 6.8e-180 599.6 0.0 7.7e-180 599.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tim17 PF02466.19 CEG38795.1 - 2.4e-05 24.7 3.4 3.1e-05 24.3 3.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 CEG38795.1 - 0.093 13.1 6.2 0.12 12.7 5.3 1.7 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2244 PF10003.9 CEG38796.1 - 0.29 10.8 1.6 0.42 10.3 1.6 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) IBR PF01485.21 CEG38797.1 - 1.2e-05 25.5 6.5 1.2e-05 25.5 6.5 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CEG38797.1 - 0.0021 17.9 3.8 0.0021 17.9 3.8 3.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG38797.1 - 0.011 15.5 1.5 0.011 15.5 1.5 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG38797.1 - 0.019 15.1 2.8 0.019 15.1 2.8 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEG38797.1 - 0.11 12.9 10.7 4 7.8 5.7 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEG38797.1 - 0.3 11.2 17.9 0.13 12.3 3.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CEG38797.1 - 1.4 9.3 23.6 6.1 7.3 6.0 2.7 2 1 0 2 2 2 0 Ring finger domain IBR PF01485.21 CEG38798.1 - 0.0012 19.1 9.4 0.0012 19.1 9.4 2.5 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 CEG38798.1 - 0.0014 18.4 5.3 0.0014 18.4 5.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 CEG38798.1 - 0.0036 17.6 12.3 0.0036 17.6 12.3 3.2 2 2 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CEG38798.1 - 0.028 14.4 12.5 0.028 14.4 12.5 3.3 2 1 1 3 3 3 0 zinc-RING finger domain RCC1 PF00415.18 CEG38799.1 - 1.7e-37 127.8 20.6 6.9e-09 36.2 0.2 8.4 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_6 PF13405.6 CEG38799.1 - 7.5e-21 72.2 2.9 0.00022 20.9 0.3 5.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CEG38799.1 - 1.6e-20 71.0 12.5 4.3e-05 22.8 0.2 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEG38799.1 - 4.2e-17 62.4 4.7 3.3e-08 33.9 3.9 3.4 2 1 1 3 3 3 3 EF-hand domain pair RCC1_2 PF13540.6 CEG38799.1 - 1.6e-14 53.3 39.7 2.7e-06 27.0 4.8 7.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat EF-hand_5 PF13202.6 CEG38799.1 - 2.6e-12 45.6 7.7 0.0091 15.5 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEG38799.1 - 1.2e-10 41.1 6.9 4.2e-05 23.3 0.9 4.5 2 1 2 4 4 4 4 EF-hand domain pair F5_F8_type_C PF00754.25 CEG38799.1 - 0.00018 21.6 0.0 0.00072 19.7 0.0 2.0 1 1 0 1 1 1 1 F5/8 type C domain EF-hand_9 PF14658.6 CEG38799.1 - 0.00059 20.1 0.4 0.18 12.2 0.2 3.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 CEG38799.1 - 0.0017 18.2 3.7 2.4 8.1 0.9 3.9 4 1 1 5 5 5 2 EF hand EF-hand_14 PF17959.1 CEG38799.1 - 0.045 14.1 0.4 4.3 7.8 0.3 3.5 2 1 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 CEG38799.1 - 0.78 9.7 4.3 16 5.5 0.0 3.2 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CEG38800.1 - 5e-44 150.7 0.0 8.3e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38800.1 - 1.3e-20 73.8 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG38800.1 - 0.023 14.0 0.1 0.055 12.8 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FbpA PF05833.11 CEG38801.1 - 0.017 13.9 0.0 0.075 11.8 0.0 1.8 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RRS1 PF04939.12 CEG38801.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Heme_oxygenase PF01126.20 CEG38802.1 - 2.7e-14 53.4 0.0 3.9e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Heme oxygenase Tyrosinase PF00264.20 CEG38802.1 - 0.00066 20.0 0.9 0.0011 19.3 0.1 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.28 CEG38803.1 - 2.9e-123 411.8 0.0 4.1e-123 411.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEG38803.1 - 6.1e-51 172.8 0.0 8.8e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CEG38803.1 - 1.2e-33 115.4 0.5 3.4e-33 113.9 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CEG38803.1 - 8.5e-22 77.1 0.1 5.2e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CEG38803.1 - 1.4e-21 77.0 0.1 2.4e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CEG38803.1 - 4.5e-19 68.5 2.2 4.5e-19 68.5 2.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CEG38803.1 - 2.8e-07 31.0 3.0 9.7e-07 29.3 3.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Lant_dehydr_C PF14028.6 CEG38804.1 - 0.051 13.1 1.4 0.086 12.4 0.4 1.8 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term SLATT_fungal PF18142.1 CEG38804.1 - 0.12 12.4 0.1 0.64 10.0 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain MucB_RseB PF03888.14 CEG38805.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 MucB/RseB N-terminal domain PRIMA1 PF16101.5 CEG38806.1 - 0.02 14.9 1.0 0.053 13.5 1.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CEG38806.1 - 0.036 13.6 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DHBP_synthase PF00926.19 CEG38807.1 - 8.2e-80 266.9 0.0 1e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 CEG38807.1 - 1.1e-05 25.1 0.2 0.031 13.9 0.1 3.5 2 1 0 2 2 2 2 GTP cyclohydrolase II Evr1_Alr PF04777.13 CEG38808.1 - 1.6e-19 70.2 0.4 3.8e-19 69.0 0.4 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 CEG38808.1 - 1.6e-16 60.1 0.1 3.4e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG38808.1 - 0.00013 22.4 0.2 0.0005 20.5 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Zn_Tnp_IS1595 PF12760.7 CEG38808.1 - 0.0094 15.9 4.6 0.28 11.2 0.3 3.3 3 0 0 3 3 3 1 Transposase zinc-ribbon domain FAD_SOX PF18371.1 CEG38808.1 - 0.012 16.0 0.0 0.038 14.4 0.0 2.0 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase AhpC-TSA PF00578.21 CEG38808.1 - 0.036 14.0 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.6 CEG38808.1 - 1.1 9.4 4.0 0.47 10.6 0.4 2.3 3 0 0 3 3 3 0 Thioredoxin DUF35_N PF12172.8 CEG38808.1 - 4.5 7.2 6.1 4.7 7.2 0.4 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LRR_8 PF13855.6 CEG38811.1 - 1.2e-35 121.1 72.8 1e-08 34.8 3.4 10.4 4 3 6 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 CEG38811.1 - 1.3e-31 108.1 73.1 1.5e-06 28.4 3.5 12.3 6 4 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG38811.1 - 1.2e-09 38.0 27.7 0.033 13.7 0.0 5.9 2 2 4 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 CEG38811.1 - 1.1e-06 28.3 51.3 1.4 9.8 0.1 15.3 13 1 2 15 15 15 3 Leucine Rich Repeat TFIIE_beta PF02186.15 CEG38811.1 - 0.013 15.8 1.1 0.79 10.0 0.4 3.2 2 0 0 2 2 2 0 TFIIE beta subunit core domain T3SS_needle_E PF08988.10 CEG38811.1 - 0.46 10.7 0.1 0.46 10.7 0.1 2.5 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle LRR_6 PF13516.6 CEG38811.1 - 0.61 10.3 52.9 2.8 8.2 0.1 12.9 14 0 0 14 14 14 0 Leucine Rich repeat LRR_8 PF13855.6 CEG38812.1 - 8.2e-39 131.2 59.5 4e-08 32.9 1.9 10.6 7 4 5 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 CEG38812.1 - 1e-24 86.2 60.7 0.00078 19.8 2.5 11.8 5 3 5 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG38812.1 - 6e-07 29.1 45.5 1.7 9.5 0.1 14.9 15 3 1 16 16 16 3 Leucine Rich Repeat LRR_9 PF14580.6 CEG38812.1 - 3.1e-06 26.8 23.3 0.02 14.4 0.1 5.5 3 2 3 6 6 6 3 Leucine-rich repeat LRR_6 PF13516.6 CEG38812.1 - 6.1e-05 22.8 39.4 1.8 8.8 0.3 11.3 13 0 0 13 13 13 5 Leucine Rich repeat NfeD PF01957.18 CEG38813.1 - 0.025 15.0 1.0 0.66 10.4 0.0 2.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding tRNA-synt_2 PF00152.20 CEG38814.1 - 3.7e-80 269.3 0.6 4.8e-80 269.0 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEG38814.1 - 5.7e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEG38814.1 - 3.5e-06 26.7 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GST_C_2 PF13410.6 CEG38814.1 - 0.068 13.2 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEG38814.1 - 0.092 13.0 0.0 0.092 13.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GCR1_C PF12550.8 CEG38814.1 - 0.18 12.2 0.1 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Mito_carr PF00153.27 CEG38819.1 - 1.9e-57 191.2 7.7 4.4e-20 71.4 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FGGY_C PF02782.16 CEG38819.1 - 0.06 13.1 0.1 0.75 9.5 0.0 2.1 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Serine_protease PF18405.1 CEG38819.1 - 0.075 12.2 4.5 0.17 11.0 0.2 3.3 5 0 0 5 5 5 0 Gammaproteobacterial serine protease Cgr1 PF03879.14 CEG38820.1 - 3e-15 56.5 22.4 3.7e-15 56.2 22.4 1.1 1 0 0 1 1 1 1 Cgr1 family Stn1 PF10451.9 CEG38820.1 - 0.12 11.4 2.8 0.14 11.1 2.8 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 AAA_11 PF13086.6 CEG38820.1 - 0.77 9.5 10.1 0.87 9.3 10.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2514 PF10721.9 CEG38820.1 - 1.3 9.0 8.3 2.1 8.4 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Cut8 PF08559.10 CEG38820.1 - 2.8 7.5 11.5 0.8 9.3 8.3 1.6 1 1 1 2 2 2 0 Cut8, nuclear proteasome tether protein GRIP PF01465.20 CEG38825.1 - 3.6e-13 49.2 0.1 9.9e-13 47.8 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Sin_N PF04801.13 CEG38827.1 - 5.2e-78 263.2 3.6 6.6e-78 262.8 3.6 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Retrotran_gag_2 PF14223.6 CEG38837.1 - 3.7e-07 29.9 0.1 4.4e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DAGAT PF03982.13 CEG38838.1 - 2e-17 63.1 0.1 3.4e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase HLH PF00010.26 CEG38839.1 - 6.4e-09 35.7 2.9 1.2e-08 34.8 2.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Wax2_C PF12076.8 CEG38839.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain DUF4536 PF15055.6 CEG38840.1 - 0.001 19.2 2.6 0.0015 18.7 2.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Peptidase_S74 PF13884.6 CEG38841.1 - 2.5e-14 53.3 0.0 1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Chaperone of endosialidase DUF3106 PF11304.8 CEG38844.1 - 0.23 11.9 1.9 2.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) LPMO_10 PF03067.15 CEG38847.1 - 1.1e-08 35.9 0.0 2.9e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 CEG38847.1 - 0.069 13.1 0.0 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 PAP2_C PF14360.6 CEG38849.1 - 2.4e-21 76.1 3.8 2.4e-21 76.1 3.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 CEG38849.1 - 5.3e-06 26.3 1.6 5.3e-06 26.3 1.6 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CEG38849.1 - 0.00039 20.2 0.3 0.00094 19.0 0.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily Asparaginase PF00710.20 CEG38851.1 - 6.7e-58 195.4 0.0 1.1e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CEG38851.1 - 9.7e-28 96.7 0.1 1.6e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain ALMT PF11744.8 CEG38852.1 - 7.1 5.3 11.8 7.8 5.2 11.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FYVE PF01363.21 CEG38858.1 - 0.0082 16.3 5.8 0.015 15.5 5.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 CEG38858.1 - 0.29 11.4 8.5 0.76 10.0 5.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DHOR PF06537.11 CEG38863.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase Prp18 PF02840.15 CEG38864.1 - 1.1e-58 197.3 0.1 1.1e-58 197.3 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CEG38864.1 - 2.1e-11 43.1 5.6 3.6e-11 42.4 5.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like SYF2 PF08231.12 CEG38864.1 - 8.3 6.8 13.8 0.13 12.7 2.6 2.6 3 0 0 3 3 3 0 SYF2 splicing factor Dev_Cell_Death PF10539.9 CEG38865.1 - 7.9e-20 71.0 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain YTH PF04146.15 CEG38865.1 - 1.8e-19 70.3 0.0 3.7e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain zf-CCCH PF00642.24 CEG38865.1 - 8.7e-16 57.4 21.4 1.3e-08 34.6 1.4 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG38865.1 - 3.1e-12 46.1 41.5 9.1e-07 28.7 3.3 5.7 6 0 0 6 6 6 3 Zinc finger domain zf-CCCH_4 PF18044.1 CEG38865.1 - 9.2e-10 38.1 29.5 9.4e-05 22.1 0.3 5.0 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG38865.1 - 1.1e-08 35.2 30.3 0.00059 20.2 2.5 5.1 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG38865.1 - 4.3e-07 30.6 17.4 0.0028 18.4 0.7 3.5 2 1 1 3 3 3 3 Torus domain KH_1 PF00013.29 CEG38865.1 - 0.0021 17.8 0.7 0.083 12.7 0.1 2.4 2 0 0 2 2 2 1 KH domain zf-CCCH_3 PF15663.5 CEG38865.1 - 0.03 14.5 16.7 0.07 13.4 4.5 3.2 1 1 1 3 3 3 0 Zinc-finger containing family IF-2B PF01008.17 CEG38866.1 - 4.7e-62 209.7 1.6 1.5e-61 208.1 1.6 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family PucR PF07905.11 CEG38866.1 - 0.096 13.0 0.5 0.72 10.1 0.1 2.3 1 1 0 2 2 2 0 Purine catabolism regulatory protein-like family NCA2 PF08637.10 CEG38867.1 - 1.9e-50 171.7 5.9 3.9e-50 170.6 5.9 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MutS_III PF05192.18 CEG38867.1 - 0.003 17.8 2.1 0.39 10.9 0.1 2.9 2 1 0 2 2 2 2 MutS domain III Arteri_nsp7a PF16749.5 CEG38867.1 - 0.11 12.7 0.4 6.7 6.9 0.1 2.6 1 1 1 2 2 2 0 Arterivirus nonstructural protein 7 alpha DUF4446 PF14584.6 CEG38867.1 - 0.12 12.3 3.6 7.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Ssl1 PF04056.14 CEG38867.1 - 0.13 12.1 2.4 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 Ssl1-like DUF3837 PF12939.7 CEG38867.1 - 0.55 10.7 3.6 2.8 8.4 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) CLZ PF16526.5 CEG38867.1 - 9.9 6.6 10.7 4.7 7.7 1.9 4.1 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Kinesin PF00225.23 CEG38868.1 - 4.6e-93 311.8 1.3 4.6e-93 311.8 1.3 2.5 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG38868.1 - 3.1e-23 82.4 0.0 3.1e-23 82.4 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding Phage-tail_3 PF13550.6 CEG38868.1 - 0.023 14.5 0.5 6.6 6.6 0.2 2.5 2 0 0 2 2 2 0 Putative phage tail protein MCC-bdg_PDZ PF10506.9 CEG38868.1 - 0.35 10.9 5.3 18 5.4 0.3 3.8 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Paramyxo_C PF01692.18 CEG38869.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Retrotran_gag_2 PF14223.6 CEG38872.1 - 5.8e-11 42.2 0.0 7.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG38872.1 - 0.00037 20.1 0.2 0.0007 19.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CEG38872.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type QSregVF_b PF12843.7 CEG38873.1 - 0.026 14.4 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor PPDFL PF15060.6 CEG38876.1 - 0.071 13.6 0.1 0.081 13.5 0.1 1.2 1 0 0 1 1 1 0 Differentiation and proliferation regulator CxC6 PF18721.1 CEG38880.1 - 0.36 11.1 42.5 0.77 10.1 7.5 4.2 1 1 1 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases RNF111_N PF15303.6 CEG38880.1 - 0.46 10.2 7.4 11 5.7 7.4 2.0 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DDE_1 PF03184.19 CEG38883.1 - 9.5e-32 110.0 0.0 1.6e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CEG38883.1 - 3e-09 36.8 0.1 1.4e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEG38883.1 - 0.00019 21.1 0.1 0.00019 21.1 0.1 2.2 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain DDE_3 PF13358.6 CEG38883.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease ABC2_membrane PF01061.24 CEG38885.1 - 3.8e-69 232.3 58.7 4.3e-37 127.6 22.6 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG38885.1 - 1.6e-36 125.9 0.0 3.8e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG38885.1 - 1.5e-07 31.5 0.0 0.14 12.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 CEG38885.1 - 3.8e-07 29.9 4.7 0.0027 17.6 0.3 3.3 2 0 0 2 2 2 2 CDR ABC transporter AAA_16 PF13191.6 CEG38885.1 - 6e-07 30.0 0.1 0.024 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEG38885.1 - 1.4e-06 28.4 2.6 0.019 14.9 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEG38885.1 - 9.2e-06 25.3 5.7 0.015 15.0 1.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CEG38885.1 - 2.2e-05 23.8 52.6 9.9e-05 21.6 17.6 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 CEG38885.1 - 9.7e-05 22.7 0.3 0.33 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEG38885.1 - 0.00018 21.2 0.1 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CEG38885.1 - 0.00021 20.8 0.6 0.46 9.9 0.2 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CEG38885.1 - 0.00031 20.1 1.4 0.035 13.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 CEG38885.1 - 0.00036 21.1 0.5 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG38885.1 - 0.002 17.9 0.4 1.1 8.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CEG38885.1 - 0.0021 17.8 0.2 0.91 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEG38885.1 - 0.0035 17.4 1.1 0.9 9.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 CEG38885.1 - 0.0035 17.7 0.5 5.9 7.3 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG38885.1 - 0.0065 17.0 0.0 2.9 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEG38885.1 - 0.019 15.1 0.1 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEG38885.1 - 0.023 14.3 0.6 1.9 8.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 CEG38885.1 - 0.028 14.4 0.2 1.7 8.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 CEG38885.1 - 0.044 13.7 0.3 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 CEG38885.1 - 0.096 12.9 1.1 6.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CEG38885.1 - 0.097 13.1 0.9 9.1 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 CEG38885.1 - 0.13 12.3 0.3 6.4 6.8 0.2 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CEG38885.1 - 0.2 10.8 0.6 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CEG38885.1 - 0.23 11.2 1.3 5.1 6.8 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CEG38885.1 - 0.31 11.1 5.4 2.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 CEG38885.1 - 0.35 10.8 5.5 8.5 6.3 0.2 2.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CEG38885.1 - 0.37 11.0 1.6 31 4.7 1.1 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CEG38885.1 - 0.56 9.9 1.8 14 5.4 0.1 3.1 3 1 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family SURNod19 PF07712.12 CEG38887.1 - 1.1e-50 172.5 10.8 7.8e-27 94.0 0.1 3.1 2 1 0 2 2 2 2 Stress up-regulated Nod 19 zf-C5HC2 PF02928.16 CEG38887.1 - 0.0091 16.4 2.2 0.0091 16.4 2.2 2.0 2 0 0 2 2 2 1 C5HC2 zinc finger RRM_1 PF00076.22 CEG38888.1 - 8.3e-19 67.2 0.2 9.1e-06 25.4 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG38888.1 - 0.00062 19.8 0.0 1 9.5 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CEG38888.1 - 0.029 14.2 0.1 0.3 11.0 0.1 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CEG38888.1 - 0.18 11.6 7.0 4.9 6.9 0.0 3.5 2 2 1 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF2149 PF09919.9 CEG38888.1 - 1 9.6 10.8 2.9 8.2 9.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) Zip PF02535.22 CEG38888.1 - 1.2 8.3 3.9 2.1 7.5 3.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter YfhO PF09586.10 CEG38888.1 - 2.9 6.0 4.6 4.7 5.3 4.6 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EMC3_TMCO1 PF01956.16 CEG38888.1 - 6.5 6.5 5.7 1.5 8.5 1.6 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DEK_C PF08766.11 CEG38889.1 - 2.5e-10 40.1 0.5 6.6e-10 38.8 0.5 1.8 1 0 0 1 1 1 1 DEK C terminal domain PP2C_C PF07830.13 CEG38889.1 - 0.0026 18.2 0.0 0.019 15.4 0.0 2.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Telomerase_RBD PF12009.8 CEG38889.1 - 1.2 9.2 6.2 0.57 10.3 0.6 2.7 2 1 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain Ank_2 PF12796.7 CEG38890.1 - 1.1e-38 131.7 1.8 2.9e-17 63.0 0.0 5.5 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG38890.1 - 2.3e-38 125.8 1.4 2e-05 24.6 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 CEG38890.1 - 4.2e-34 116.5 1.3 8.2e-09 35.8 0.0 8.4 4 3 4 8 8 8 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 CEG38890.1 - 2.2e-32 112.2 0.0 1.2e-17 64.6 0.0 2.9 3 0 0 3 3 3 2 TIR domain Ank PF00023.30 CEG38890.1 - 2.3e-32 110.0 5.7 2.4e-05 24.6 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 CEG38890.1 - 7.8e-27 93.0 1.9 1.1e-05 25.6 0.0 6.7 4 1 2 6 6 6 6 Ankyrin repeats (many copies) TIR PF01582.20 CEG38890.1 - 1.8e-07 31.1 0.1 0.0018 18.1 0.0 2.8 3 0 0 3 3 3 2 TIR domain DUF1863 PF08937.11 CEG38890.1 - 4.9e-07 30.1 0.4 0.0083 16.4 0.1 3.0 2 2 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) Caa3_CtaG PF09678.10 CEG38890.1 - 0.076 12.5 1.6 0.14 11.6 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Complex1_LYR_2 PF13233.6 CEG38890.1 - 1 10.1 2.7 20 6.0 0.3 3.2 3 1 0 3 3 3 0 Complex1_LYR-like Put_Phosphatase PF06888.12 CEG38891.1 - 2.4e-87 292.2 2.9 3.4e-52 177.2 0.1 3.0 2 1 1 3 3 3 3 Putative Phosphatase HAD PF12710.7 CEG38891.1 - 1.7e-08 35.1 0.6 0.00032 21.1 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase B3 PF02362.21 CEG38891.1 - 0.037 13.9 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 B3 DNA binding domain PolyA_pol_RNAbd PF12627.7 CEG38891.1 - 0.14 12.0 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A TBCC PF07986.12 CEG38892.1 - 1.3e-39 134.7 1.6 1.3e-39 134.7 1.6 2.4 2 0 0 2 2 2 1 Tubulin binding cofactor C DHHC PF01529.20 CEG38892.1 - 2.9e-29 101.9 13.6 7.6e-29 100.5 13.6 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase Glycos_transf_2 PF00535.26 CEG38892.1 - 5e-25 88.3 0.1 1.3e-24 86.9 0.2 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEG38892.1 - 2.8e-08 33.9 0.3 5.7e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CEG38892.1 - 3.9e-08 33.1 0.1 7.1e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CAP_C PF08603.11 CEG38892.1 - 0.93 9.1 4.2 4.7 6.8 0.8 2.4 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) C terminal UDPGT PF00201.18 CEG38893.1 - 6.4e-20 71.4 0.2 5.5e-15 55.1 0.1 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEG38893.1 - 3.8e-07 30.2 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RGS PF00615.19 CEG38894.1 - 0.33 11.2 5.6 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF4006 PF13179.6 CEG38897.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) NPP1 PF05630.11 CEG38899.1 - 3.1e-48 164.5 0.0 3.6e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 CEG38901.1 - 3.6e-49 167.6 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF1819 PF08849.11 CEG38904.1 - 0.035 13.9 0.0 0.04 13.7 0.0 1.0 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Pantoate_transf PF02548.15 CEG38905.1 - 1.7e-90 302.9 2.2 7.7e-63 212.3 0.3 2.2 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CEG38905.1 - 0.00082 18.9 0.6 0.0072 15.8 0.1 2.4 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FAA_hydrolase_N PF09298.11 CEG38906.1 - 2.8e-23 82.1 0.0 4.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAA_hydrolase PF01557.18 CEG38906.1 - 1.8e-08 34.4 0.0 2.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.18 CEG38907.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family zf-BED PF02892.15 CEG38908.1 - 3.3e-05 23.8 8.2 0.28 11.3 1.6 4.5 3 1 0 3 3 3 3 BED zinc finger EST1_DNA_bind PF10373.9 CEG38908.1 - 0.027 14.0 0.3 0.08 12.4 0.1 1.9 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain ANAPC3 PF12895.7 CEG38908.1 - 0.45 10.8 2.7 0.33 11.2 0.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-U11-48K PF05253.12 CEG38908.1 - 0.82 9.7 9.8 15 5.6 0.6 3.8 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger zf_C2HC_14 PF18574.1 CEG38908.1 - 1.2 9.0 9.8 3.3 7.6 0.1 3.4 3 0 0 3 3 3 0 C2HC Zing finger domain STI1 PF17830.1 CEG38909.1 - 3.4e-14 52.5 9.3 2.2e-06 27.5 0.1 3.6 2 1 1 3 3 3 2 STI1 domain Cnn_1N PF07989.11 CEG38909.1 - 0.0049 17.0 0.6 0.0049 17.0 0.6 7.5 4 2 3 7 7 7 2 Centrosomin N-terminal motif 1 SNF2_N PF00176.23 CEG38911.1 - 7.6e-78 261.7 0.0 1.5e-77 260.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG38911.1 - 3.8e-18 65.8 0.0 1.4e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CEG38911.1 - 4.2e-10 39.3 5.2 4.2e-10 39.3 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG38911.1 - 2.7e-08 33.5 7.4 7.9e-08 32.1 7.4 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 CEG38911.1 - 5.7e-08 32.9 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 CEG38911.1 - 6.7e-08 32.4 4.3 6.7e-08 32.4 4.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG38911.1 - 1.3e-07 31.3 6.5 1.3e-07 31.3 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CEG38911.1 - 1.6e-07 31.3 0.0 5.2e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 CEG38911.1 - 1.3e-06 28.6 8.3 1.3e-06 28.6 8.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG38911.1 - 1.9e-06 27.6 9.0 1.9e-06 27.6 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG38911.1 - 5.4e-05 23.1 7.5 5.8e-05 23.0 5.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger HIRAN PF08797.11 CEG38911.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain ERCC3_RAD25_C PF16203.5 CEG38911.1 - 0.00022 20.6 0.0 0.00082 18.7 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-RanBP PF00641.18 CEG38911.1 - 0.0016 17.8 1.7 0.0047 16.2 1.7 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1644 PF07800.12 CEG38911.1 - 0.3 11.1 6.5 0.19 11.7 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.6 CEG38911.1 - 1.5 8.6 5.3 4 7.3 5.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0004 PF00919.20 CEG38912.1 - 2.1e-30 104.6 0.1 4.5e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 CEG38912.1 - 1.2e-28 100.6 0.0 2.9e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 CEG38912.1 - 0.13 12.3 0.0 2.3 8.3 0.0 2.6 3 0 0 3 3 3 0 TRAM domain Prefoldin_2 PF01920.20 CEG38913.1 - 3.7e-21 75.1 11.8 5.1e-21 74.6 11.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CEG38913.1 - 0.018 15.0 8.1 0.17 11.8 8.1 2.2 1 1 0 1 1 1 0 Prefoldin subunit KASH_CCD PF14662.6 CEG38913.1 - 0.082 12.7 18.9 0.031 14.1 6.2 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5089 PF17002.5 CEG38913.1 - 0.091 12.6 7.9 0.14 12.0 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) DUF1653 PF07866.11 CEG38913.1 - 0.13 12.6 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) HAP1_N PF04849.13 CEG38913.1 - 0.77 8.9 12.2 1.3 8.1 12.2 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF948 PF06103.11 CEG38913.1 - 1 9.7 6.1 1.2 9.4 0.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 CEG38913.1 - 1 10.0 14.5 2.9 8.5 1.9 2.2 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SOGA PF11365.8 CEG38913.1 - 1.1 10.4 9.4 0.65 11.2 1.7 2.4 1 1 0 2 2 2 0 Protein SOGA APG6_N PF17675.1 CEG38913.1 - 7.5 7.1 14.1 75 3.9 13.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Sugar_tr PF00083.24 CEG38916.1 - 7.1e-111 371.3 22.4 1.1e-110 370.6 22.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG38916.1 - 2.4e-24 85.9 37.2 2.4e-24 85.9 37.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEG38916.1 - 0.091 11.2 9.0 0.0084 14.6 4.5 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) EMP70 PF02990.16 CEG38916.1 - 1 7.9 8.8 2.2 6.8 8.8 1.6 1 0 0 1 1 1 0 Endomembrane protein 70 Cu-oxidase_2 PF07731.14 CEG38917.1 - 2.5e-21 75.8 0.6 2.5e-21 75.8 0.6 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEG38917.1 - 1.4e-12 47.6 6.0 5e-10 39.4 2.3 3.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 CEG38917.1 - 0.00029 21.0 0.0 0.00072 19.7 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Phage_head_chap PF11113.8 CEG38919.1 - 0.16 12.1 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Head assembly gene product ADH_zinc_N PF00107.26 CEG38920.1 - 5.8e-26 91.0 0.1 9.3e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEG38920.1 - 1.5e-24 86.0 4.2 3.3e-24 84.9 3.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CEG38920.1 - 0.00015 22.9 0.0 0.00027 22.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CEG38920.1 - 0.0074 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF359 PF04019.12 CEG38920.1 - 0.084 12.5 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF359) Epimerase PF01370.21 CEG38920.1 - 0.17 11.3 0.1 0.39 10.1 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family START PF01852.19 CEG38926.1 - 1.8e-21 76.6 0.1 4.3e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 START domain FYVE PF01363.21 CEG38926.1 - 4.4e-18 65.2 11.8 8e-18 64.4 11.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG38926.1 - 0.0032 17.6 4.8 0.0079 16.4 4.8 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Serpulina_VSP PF05540.11 CEG38926.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein AAA_lid_6 PF17866.1 CEG38926.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain IBR PF01485.21 CEG38926.1 - 1.3 9.3 8.5 0.22 11.8 4.3 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 CEG38926.1 - 3.3 7.8 11.0 6.6 6.8 11.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-CRD PF17979.1 CEG38926.1 - 4.9 7.2 9.6 8.6 6.4 7.2 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions DZR PF12773.7 CEG38926.1 - 7.2 6.7 11.3 7e+02 0.4 11.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 CEG38926.1 - 7.5 6.8 11.3 6.8 6.9 5.9 2.4 2 0 0 2 2 2 0 B-box zinc finger AAA_12 PF13087.6 CEG38929.1 - 4.1e-35 121.2 0.0 7.2e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG38929.1 - 3.9e-20 72.7 1.3 1.4e-19 70.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG38929.1 - 2.3e-07 30.8 0.1 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CEG38929.1 - 3.1e-06 27.6 0.1 3.9e-05 24.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain zf_CCCH_4 PF18345.1 CEG38929.1 - 0.00015 21.7 6.6 0.00056 19.9 6.6 2.1 1 0 0 1 1 1 1 Zinc finger domain DUF2075 PF09848.9 CEG38929.1 - 0.00032 20.1 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Big_6 PF17936.1 CEG38930.1 - 9.2e-08 32.3 0.1 1.2e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial Ig domain CarboxypepD_reg PF13620.6 CEG38930.1 - 0.0035 17.6 0.2 0.0054 17.0 0.2 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF953 PF06110.11 CEG38934.1 - 0.0045 16.6 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) PX PF00787.24 CEG38934.1 - 0.024 14.6 0.5 0.052 13.5 0.5 1.7 1 1 0 1 1 1 0 PX domain Glutaredoxin PF00462.24 CEG38934.1 - 0.056 13.7 0.8 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin PH_TFIIH PF08567.11 CEG38935.1 - 0.056 13.8 0.0 0.063 13.6 0.0 1.1 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain IPP-2 PF04979.14 CEG38937.1 - 2.3e-24 86.6 14.2 3.3e-24 86.1 14.2 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SHIPPO-rpt PF07004.12 CEG38938.1 - 9.6e-18 64.2 17.7 0.005 17.7 0.7 5.9 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat VIT1 PF01988.19 CEG38940.1 - 2.9e-57 194.0 0.4 3.5e-57 193.7 0.4 1.1 1 0 0 1 1 1 1 VIT family DUF2019 PF09450.10 CEG38940.1 - 0.006 16.5 0.3 0.44 10.5 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2019) ANAPC4_WD40 PF12894.7 CEG38941.1 - 3.1e-08 33.8 0.1 0.14 12.5 0.1 5.2 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEG38941.1 - 8e-05 20.9 0.0 0.00023 19.4 0.0 1.6 2 0 0 2 2 2 1 IKI3 family eIF2A PF08662.11 CEG38941.1 - 0.00079 19.4 0.1 0.2 11.5 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEG38941.1 - 0.0051 16.2 0.2 0.06 12.7 0.2 2.6 1 1 0 1 1 1 1 WD40-like domain PKD PF00801.20 CEG38941.1 - 0.083 12.7 0.2 15 5.5 0.0 2.6 2 0 0 2 2 2 0 PKD domain YecM PF06185.12 CEG38941.1 - 0.095 12.4 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 YecM protein POB3_N PF17292.2 CEG38941.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 POB3-like N-terminal PH domain cNMP_binding PF00027.29 CEG38942.1 - 4.4e-19 68.3 0.9 9.9e-09 35.2 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CEG38942.1 - 0.053 13.2 0.2 3 7.6 0.0 2.7 2 1 0 2 2 2 0 Cupin domain Hema_HEFG PF02710.14 CEG38942.1 - 0.17 12.1 1.0 0.41 10.8 1.0 1.6 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein CPSase_L_D2 PF02786.17 CEG38943.1 - 3.6e-78 261.9 0.1 6.4e-78 261.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEG38943.1 - 2.6e-43 147.0 0.1 6.6e-43 145.7 0.1 1.7 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEG38943.1 - 9.9e-36 122.1 0.0 2.4e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEG38943.1 - 9.3e-18 63.8 0.5 5.7e-17 61.3 0.5 2.3 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CEG38943.1 - 8.1e-09 35.9 0.0 1.2e-07 32.2 0.0 2.3 1 1 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CEG38943.1 - 1.6e-07 31.1 0.1 4.9e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEG38943.1 - 4.4e-07 29.6 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CEG38943.1 - 0.00026 20.6 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 CEG38943.1 - 0.0014 18.2 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEG38943.1 - 0.0072 16.4 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 CEG38943.1 - 0.0093 15.2 0.0 0.038 13.2 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 CEG38943.1 - 0.013 15.3 0.1 0.076 12.8 0.0 2.4 3 0 0 3 3 3 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 CEG38943.1 - 0.014 15.1 0.0 0.09 12.5 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 CEG38943.1 - 0.082 12.9 0.5 0.4 10.7 0.3 2.4 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 CEG38943.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Yippee-Mis18 PF03226.14 CEG38945.1 - 5e-12 46.0 0.1 7.2e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CEG38945.1 - 0.13 12.5 0.3 0.34 11.1 0.3 1.7 1 1 1 2 2 2 0 C-terminal domain of RIG-I LSM PF01423.22 CEG38946.1 - 9.1e-20 70.1 0.2 1.2e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain Pex2_Pex12 PF04757.14 CEG38947.1 - 1.1e-18 67.7 6.8 1.2e-17 64.3 6.8 2.0 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CEG38947.1 - 7e-09 35.9 12.1 2.4e-08 34.2 12.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEG38947.1 - 1.9e-08 34.0 10.0 4.4e-08 32.9 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG38947.1 - 3e-08 33.4 9.5 7.2e-08 32.2 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG38947.1 - 3.6e-08 33.1 11.1 8.6e-08 31.9 11.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG38947.1 - 1.5e-07 31.2 9.9 2.9e-07 30.2 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEG38947.1 - 8.7e-06 25.7 11.1 4.5e-05 23.4 11.2 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG38947.1 - 2.3e-05 24.2 9.8 2.3e-05 24.2 9.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEG38947.1 - 4.7e-05 23.6 7.9 0.00017 21.8 7.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CEG38947.1 - 0.00037 20.6 11.2 0.00037 20.6 11.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CEG38947.1 - 0.0018 18.3 3.4 0.0053 16.8 2.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CEG38947.1 - 0.47 10.4 8.4 0.34 10.8 6.3 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CEG38947.1 - 0.52 10.1 10.2 1.1 9.0 10.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CEG38947.1 - 1.1 9.1 6.4 0.31 10.8 2.9 2.0 2 0 0 2 2 2 0 RING-like zinc finger peroxidase PF00141.23 CEG38948.1 - 4.5e-08 33.1 0.0 1.5e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Acyl-CoA_dh_1 PF00441.24 CEG38953.1 - 1.5e-42 145.4 1.3 2.5e-42 144.6 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG38953.1 - 1.5e-30 106.2 0.0 8.3e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEG38953.1 - 4e-26 91.1 0.0 6.4e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG38953.1 - 3.4e-16 59.7 0.2 5.7e-16 59.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DnaJ PF00226.31 CEG38954.1 - 2.8e-06 27.4 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CEG38954.1 - 3e-05 24.0 0.0 3.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Pam16 HTH_10 PF04967.12 CEG38954.1 - 0.058 13.2 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DHR-2 PF06920.13 CEG38955.1 - 1.1e-51 176.2 0.0 1.2e-49 169.4 0.0 2.2 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 CEG38955.1 - 4.2e-37 127.9 0.2 8.3e-37 126.9 0.2 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF1192 PF06698.11 CEG38955.1 - 0.15 12.1 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MSP1_C PF07462.11 CEG38958.1 - 0.13 10.9 0.2 0.16 10.7 0.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus UCH PF00443.29 CEG38959.1 - 5.5e-43 147.3 0.0 8.6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CEG38959.1 - 1.7e-22 78.9 0.5 6.3e-10 38.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 CEG38959.1 - 7e-15 55.4 0.1 1.6e-11 44.3 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEG38959.1 - 4.7e-10 39.6 0.0 1.9e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 CEG38959.1 - 0.12 11.9 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase UBA_5 PF16577.5 CEG38959.1 - 0.14 12.3 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 UBA domain IQ PF00612.27 CEG38960.1 - 2e-12 45.7 35.7 0.00011 21.7 0.1 7.7 7 0 0 7 7 7 6 IQ calmodulin-binding motif Lactamase_B_6 PF16661.5 CEG38960.1 - 5.7e-11 42.2 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CEG38960.1 - 7e-05 23.1 0.6 0.00087 19.6 0.0 2.8 3 0 0 3 3 3 1 Beta-Casp domain Prismane PF03063.20 CEG38960.1 - 0.21 10.3 1.4 0.42 9.2 1.4 1.4 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family ThiF PF00899.21 CEG38965.1 - 7.8e-69 231.7 0.2 1.1e-68 231.2 0.2 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CEG38965.1 - 7.1e-22 77.8 0.1 1.4e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CEG38965.1 - 1.4e-09 38.2 1.1 1.3e-07 31.8 0.2 2.5 2 1 0 2 2 2 1 Ubiquitin-activating enzyme active site E2_bind PF08825.10 CEG38965.1 - 0.001 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 E2 binding domain NAD_binding_7 PF13241.6 CEG38965.1 - 0.0012 19.2 0.0 0.0044 17.4 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CEG38965.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CEG38965.1 - 0.031 14.8 0.9 0.66 10.6 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HEAT PF02985.22 CEG38966.1 - 2.7e-13 48.9 19.5 0.012 15.8 0.1 10.2 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 CEG38966.1 - 5.5e-13 49.1 3.6 0.066 13.6 0.0 6.9 6 1 1 7 7 6 4 HEAT repeats PDZ_6 PF17820.1 CEG38966.1 - 1.6e-10 40.7 0.5 9.3e-06 25.4 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CEG38966.1 - 1.3e-07 31.8 0.1 0.0046 17.3 0.0 2.9 3 0 0 3 3 3 2 PDZ domain UBA_4 PF14555.6 CEG38966.1 - 1.3e-06 28.1 0.1 0.24 11.2 0.0 3.6 3 0 0 3 3 3 2 UBA-like domain PDZ PF00595.24 CEG38966.1 - 4.1e-06 27.1 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Vac14_Fab1_bd PF12755.7 CEG38966.1 - 0.0017 18.9 0.0 2.3 8.9 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF1987 PF09345.10 CEG38966.1 - 0.015 15.0 0.0 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) Ig_mannosidase PF17753.1 CEG38966.1 - 0.056 13.2 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Ig-fold domain DUF1296 PF06972.11 CEG38966.1 - 0.067 13.3 0.1 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) HEAT_EZ PF13513.6 CEG38966.1 - 0.11 13.0 0.6 27 5.4 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat NAM-associated PF14303.6 CEG38967.1 - 0.00013 22.7 0.9 0.00036 21.3 0.3 2.0 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain Myb_DNA-bind_2 PF08914.11 CEG38967.1 - 0.037 14.2 0.7 0.13 12.5 0.5 1.9 2 0 0 2 2 2 0 Rap1 Myb domain PheRS_DBD1 PF18552.1 CEG38968.1 - 0.0087 15.8 0.2 12 5.7 0.0 3.4 3 0 0 3 3 3 2 PheRS DNA binding domain 1 Pkinase PF00069.25 CEG38969.1 - 1.3e-70 237.8 0.0 2.1e-70 237.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38969.1 - 2.6e-41 141.7 0.0 4.2e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG38969.1 - 0.00013 21.4 0.0 0.00053 19.4 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CEG38969.1 - 0.00087 18.2 2.0 0.016 14.0 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase RRM_1 PF00076.22 CEG38972.1 - 9.5e-14 51.0 0.1 2.2e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 CEG38972.1 - 1.5e-11 44.1 0.2 2.9e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3109 PF11307.8 CEG38974.1 - 0.021 14.6 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) ComA PF02679.15 CEG38974.1 - 0.19 11.2 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) BPS1 PF05633.11 CEG38975.1 - 1.3 8.0 8.1 6.2 5.7 2.8 2.1 2 0 0 2 2 2 0 Protein BYPASS1-related Herpes_TAF50 PF03326.13 CEG38976.1 - 0.012 14.3 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PDZ PF00595.24 CEG38976.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 CEG38977.1 - 4.5e-55 186.9 0.0 6.7e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG38977.1 - 7.5e-22 77.9 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CEG38977.1 - 2.9e-15 56.5 0.3 6.4e-05 23.3 0.0 4.9 5 1 1 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 CEG38977.1 - 2.2e-14 51.8 1.1 0.00056 19.3 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CEG38977.1 - 6.7e-13 47.5 4.5 0.0045 16.8 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CEG38977.1 - 7.8e-10 38.5 2.5 0.012 15.5 0.0 4.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG38977.1 - 5.9e-08 31.9 3.0 0.0014 18.1 0.0 3.6 3 0 0 3 3 3 2 EF hand Pkinase_fungal PF17667.1 CEG38977.1 - 0.064 12.0 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sigma54_activ_2 PF14532.6 CEG38977.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PSS PF03034.15 CEG38978.1 - 2.2e-91 306.4 16.6 3.6e-91 305.7 16.6 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase adh_short_C2 PF13561.6 CEG38980.1 - 6.4e-05 22.6 0.0 0.02 14.4 0.0 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG38980.1 - 0.0022 17.5 0.1 0.027 14.0 0.1 2.7 1 1 0 1 1 1 1 short chain dehydrogenase zf-C2H2_12 PF18658.1 CEG38980.1 - 3.1 7.4 4.4 29 4.3 3.4 2.6 2 1 0 2 2 2 0 Zinc-finger C2H2-type AAA PF00004.29 CEG38981.1 - 1.5e-42 145.1 0.1 9.1e-42 142.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG38981.1 - 9.5e-09 34.9 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 CEG38981.1 - 4.9e-05 23.1 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CEG38981.1 - 0.0001 22.5 0.0 0.00033 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CEG38981.1 - 0.00013 21.8 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEG38981.1 - 0.00035 19.9 0.1 0.00078 18.7 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CEG38981.1 - 0.00052 20.0 0.7 0.0031 17.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG38981.1 - 0.00059 20.3 0.6 0.00059 20.3 0.6 3.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG38981.1 - 0.0011 19.3 8.0 0.01 16.1 0.4 4.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEG38981.1 - 0.0034 17.6 0.0 0.0034 17.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CEG38981.1 - 0.015 15.0 0.1 0.062 13.0 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.6 CEG38981.1 - 0.016 15.8 0.0 0.11 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEG38981.1 - 0.017 14.6 0.0 0.061 12.8 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CEG38981.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEG38981.1 - 0.071 13.2 0.0 0.26 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain GST_N_5 PF18485.1 CEG38981.1 - 0.23 11.8 0.8 2 8.8 0.0 3.0 3 0 0 3 3 2 0 Glutathione S-transferase, N-terminal domain AAA_28 PF13521.6 CEG38981.1 - 0.96 9.7 5.5 1.2 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CEG38981.1 - 1.1 9.8 11.0 27 5.2 8.6 2.5 2 0 0 2 2 2 0 AAA domain RVT_2 PF07727.14 CEG38982.1 - 1.2e-13 51.2 0.1 1.3e-13 51.1 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_6 PF13405.6 CEG38986.1 - 0.00083 19.1 0.6 1.9 8.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain ubiquitin PF00240.23 CEG38986.1 - 0.0018 18.0 0.1 0.0081 15.9 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin family EF-hand_1 PF00036.32 CEG38986.1 - 0.0048 16.4 0.2 1.1 9.0 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG38986.1 - 0.0053 17.2 0.4 0.014 15.8 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair Ribul_P_3_epim PF00834.19 CEG38988.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Viral_P18 PF04521.13 CEG38990.1 - 0.072 12.9 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Osteopontin PF00865.18 CEG38993.1 - 0.0055 16.2 0.7 0.0064 16.0 0.7 1.0 1 0 0 1 1 1 1 Osteopontin GldM_N PF12081.8 CEG38993.1 - 0.025 14.7 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Cytochrom_C PF00034.21 CEG38996.1 - 8.5e-17 62.1 0.2 1.2e-16 61.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CEG38996.1 - 9.3e-07 29.1 2.6 4.4e-06 26.9 2.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CEG38996.1 - 0.0019 17.9 0.4 0.0045 16.7 0.3 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 CEG38996.1 - 0.072 13.4 0.8 2.3 8.6 0.2 2.1 2 0 0 2 2 2 0 Cytochrome P460 CCP_MauG PF03150.14 CEG38996.1 - 0.088 13.5 0.0 0.095 13.3 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Brix PF04427.18 CEG38997.1 - 9.5e-30 104.1 1.1 9.5e-30 104.1 1.1 1.5 2 0 0 2 2 2 1 Brix domain EcoRII-C PF09019.11 CEG38997.1 - 0.02 15.0 2.5 0.022 14.9 0.2 2.1 3 0 0 3 3 3 0 EcoRII C terminal Phage_Nu1 PF07471.12 CEG38997.1 - 1.4 8.7 5.0 1.5 8.5 3.1 1.9 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 CCDC92 PF14916.6 CEG39000.1 - 0.0063 16.3 2.0 0.0063 16.3 2.0 5.3 4 3 1 5 5 5 2 Coiled-coil domain of unknown function ZapB PF06005.12 CEG39000.1 - 0.011 16.1 6.0 0.011 16.1 6.0 6.1 2 1 2 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 CEG39000.1 - 0.027 15.0 19.5 0.027 15.0 19.5 4.4 2 2 2 4 4 4 0 Apg6 coiled-coil region Hydin_ADK PF17213.3 CEG39001.1 - 1.2 9.4 7.3 0.55 10.5 0.6 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CDC45 PF02724.14 CEG39001.1 - 5.5 5.1 8.2 6.4 4.9 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pro_isomerase PF00160.21 CEG39005.1 - 3.1e-42 144.5 0.0 3.5e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 CEG39007.1 - 9.2e-91 305.1 0.0 1.2e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CEG39007.1 - 0.011 16.1 0.1 0.022 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain EP400_N PF15790.5 CEG39007.1 - 0.042 12.7 0.2 0.063 12.1 0.2 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal ISET-FN3_linker PF16625.5 CEG39007.1 - 0.069 13.7 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO NAC PF01849.18 CEG39007.1 - 0.1 12.6 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 NAC domain ABC_tran PF00005.27 CEG39007.1 - 0.11 13.0 0.3 0.24 11.9 0.3 1.8 1 1 0 1 1 1 0 ABC transporter Myosin_N PF02736.19 CEG39007.1 - 0.13 12.1 0.5 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF2958 PF11171.8 CEG39009.1 - 0.067 13.5 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) UDPGP PF01704.18 CEG39011.1 - 2.9e-123 411.6 0.0 3.8e-123 411.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 CEG39011.1 - 1.9e-27 95.7 0.0 4.8e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CEG39011.1 - 5.3e-25 87.8 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CEG39011.1 - 1.4e-07 32.0 0.0 6.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CEG39011.1 - 7.3e-05 22.9 0.1 0.00033 20.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PPR_2 PF13041.6 CEG39013.1 - 9e-27 93.0 9.6 4.2e-11 42.9 0.7 8.2 8 2 2 10 10 10 5 PPR repeat family PPR_3 PF13812.6 CEG39013.1 - 2.2e-24 85.3 2.2 2.7e-08 33.8 0.2 7.8 6 3 3 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 CEG39013.1 - 4.5e-21 73.6 18.4 4.6e-06 26.5 0.5 11.5 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.7 CEG39013.1 - 3e-18 65.2 0.5 0.0035 17.0 0.1 6.3 5 1 1 6 6 6 5 PPR repeat PPR_long PF17177.4 CEG39013.1 - 1.9e-11 43.8 2.0 0.00071 19.0 0.0 4.7 2 1 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 CEG39013.1 - 0.0004 20.4 1.4 0.052 13.6 0.0 3.8 4 1 0 4 4 4 1 Cytochrome c oxidase subunit Va TPR_12 PF13424.6 CEG39013.1 - 0.0017 18.6 0.6 6.4 7.1 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39013.1 - 0.0049 16.8 0.2 1.9 8.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39013.1 - 0.0072 17.1 2.8 32 5.7 0.0 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 CEG39013.1 - 0.025 13.8 0.7 2.1 7.5 0.0 4.1 5 2 1 6 6 6 0 Tetratricopeptide repeat DUF5526 PF17664.1 CEG39013.1 - 0.054 13.0 1.7 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5526) CLP1_P PF16575.5 CEG39014.1 - 7.3e-56 188.9 0.0 1.1e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CEG39014.1 - 7.1e-31 106.3 0.0 1.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CEG39014.1 - 5.7e-25 88.0 0.0 9.4e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 CEG39014.1 - 0.0044 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CEG39014.1 - 0.04 14.5 0.1 0.13 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CEG39014.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CEG39014.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 CEG39014.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CEG39016.1 - 1.7e-72 242.5 0.4 1.9e-72 242.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG39016.1 - 2.5e-15 56.8 0.1 3.4e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG39016.1 - 5e-13 49.0 0.0 5.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CEG39016.1 - 1.6e-11 44.0 2.4 2.7e-06 26.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEG39016.1 - 1.1e-10 41.3 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG39016.1 - 1.1e-10 41.3 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG39016.1 - 3.5e-07 30.3 0.0 5.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG39016.1 - 0.00023 20.8 0.0 0.0016 18.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain KH_2 PF07650.17 CEG39016.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 KH domain TniB PF05621.11 CEG39016.1 - 0.023 14.1 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 CEG39016.1 - 0.048 13.6 0.2 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 CEG39016.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEG39016.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 1 1 2 2 2 0 AAA domain PPK2 PF03976.14 CEG39016.1 - 0.27 10.7 1.4 0.74 9.3 0.0 2.0 2 1 1 3 3 3 0 Polyphosphate kinase 2 (PPK2) RtcB PF01139.17 CEG39017.1 - 0.027 13.7 4.0 0.032 13.4 2.2 2.0 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB SPC12 PF06645.13 CEG39018.1 - 1.9e-25 88.7 1.3 2.1e-25 88.6 1.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Cas1_AcylT PF07779.12 CEG39018.1 - 0.032 13.2 0.4 0.032 13.2 0.4 1.2 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p PIG-U PF06728.13 CEG39019.1 - 1.7e-88 297.3 33.8 1.9e-88 297.1 33.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PCI PF01399.27 CEG39020.1 - 3.8e-13 49.9 0.1 2.2e-12 47.4 0.0 2.3 2 1 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CEG39020.1 - 0.00094 19.2 0.6 0.004 17.1 0.0 2.2 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family Sigma70_r4_2 PF08281.12 CEG39020.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 eIF3m_C_helix PF18005.1 CEG39020.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.8 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF1674 PF07896.12 CEG39021.1 - 2.4e-09 37.5 5.4 5.4e-09 36.4 5.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Exo_endo_phos PF03372.23 CEG39023.1 - 3e-05 23.7 0.0 4e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_lysis PF03245.13 CEG39023.1 - 0.044 13.9 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Exo_endo_phos_2 PF14529.6 CEG39023.1 - 0.095 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF3887 PF13026.6 CEG39024.1 - 0.068 14.0 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) WD40 PF00400.32 CEG39025.1 - 1.9 9.5 5.2 40 5.3 0.1 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF900 PF05990.12 CEG39026.1 - 4e-17 62.5 0.0 1.2e-15 57.7 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CEG39026.1 - 0.0041 17.8 0.2 0.022 15.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Monooxygenase_B PF04744.12 CEG39026.1 - 0.46 9.3 8.4 0.68 8.7 8.4 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein Metallophos PF00149.28 CEG39027.1 - 7.5e-07 29.8 0.1 1.4e-05 25.7 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 CEG39028.1 - 4.7e-07 30.5 1.5 1.6e-06 28.8 0.4 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase CorA PF01544.18 CEG39030.1 - 3.3e-43 148.1 1.4 8.6e-38 130.3 0.5 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_8 PF13833.6 CEG39030.1 - 3.2e-06 26.9 1.4 0.0033 17.2 0.7 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CEG39030.1 - 4.9e-06 26.9 1.0 2.8e-05 24.5 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG39030.1 - 0.00015 21.1 0.9 0.00053 19.3 0.6 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEG39030.1 - 0.00071 19.3 0.4 0.017 15.0 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CEG39030.1 - 0.028 13.9 0.6 0.076 12.5 0.6 1.7 1 0 0 1 1 1 0 EF hand Pkinase PF00069.25 CEG39032.1 - 1.2e-41 142.9 0.0 5.6e-40 137.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39032.1 - 1.1e-37 129.7 0.0 1.7e-35 122.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEG39032.1 - 0.00078 19.4 0.0 0.0031 17.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4448 PF14610.6 CEG39032.1 - 0.0063 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 CEG39032.1 - 0.012 15.3 4.3 0.023 14.5 4.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin_C_2 PF16492.5 CEG39032.1 - 0.014 16.2 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Hum_adeno_E3A PF05393.11 CEG39032.1 - 0.027 14.4 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMEM154 PF15102.6 CEG39032.1 - 0.044 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Kdo PF06293.14 CEG39032.1 - 0.053 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAG1 PF05454.11 CEG39032.1 - 0.12 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Haspin_kinase PF12330.8 CEG39032.1 - 0.19 10.6 0.0 0.37 9.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain BT1 PF03092.16 CEG39033.1 - 3.7e-06 25.5 14.2 1.2e-05 23.7 2.6 3.0 2 1 0 2 2 2 2 BT1 family ATPase_gene1 PF09527.10 CEG39036.1 - 0.081 13.1 3.0 0.16 12.1 3.0 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter FAM176 PF14851.6 CEG39036.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM176 family PulG PF11773.8 CEG39038.1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Viral_NABP PF05515.11 CEG39039.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral nucleic acid binding DUF3198 PF11433.8 CEG39043.1 - 0.044 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Ank_2 PF12796.7 CEG39044.1 - 1.9e-51 172.6 10.4 2.7e-18 66.3 0.2 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG39044.1 - 2e-24 85.3 9.7 2.2e-07 31.0 0.1 7.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG39044.1 - 4.2e-24 84.6 3.1 3.2e-08 34.0 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG39044.1 - 4.4e-22 77.5 9.9 6.3e-05 23.2 0.0 6.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 CEG39044.1 - 2e-18 64.5 6.1 0.0024 18.2 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat SAPS PF04499.15 CEG39044.1 - 3.6e-08 32.6 0.1 7.2e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF2860 PF11059.8 CEG39045.1 - 0.032 13.5 0.0 0.032 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) HA PF03457.14 CEG39049.1 - 5.2e-25 87.6 2.4 3.1e-09 37.0 0.1 5.4 5 0 0 5 5 5 5 Helicase associated domain PG_binding_2 PF08823.11 CEG39049.1 - 0.0029 17.9 0.4 0.5 10.7 0.0 4.1 5 1 1 6 6 6 1 Putative peptidoglycan binding domain MNSV_P7B PF06692.11 CEG39049.1 - 0.053 13.5 0.4 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein PerC PF06069.11 CEG39049.1 - 0.18 12.0 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 PerC transcriptional activator DUF1358 PF07096.11 CEG39050.1 - 0.062 13.3 0.4 0.11 12.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) LRR_6 PF13516.6 CEG39051.1 - 9e-21 72.1 33.8 0.0079 16.2 0.1 10.6 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.7 CEG39051.1 - 6e-10 39.2 24.9 0.05 14.0 0.2 7.3 5 2 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG39051.1 - 0.0016 18.2 26.9 0.044 13.6 3.1 7.8 5 3 2 7 7 6 3 Leucine rich repeat LRR_1 PF00560.33 CEG39051.1 - 0.011 16.2 19.7 7.4 7.6 0.1 8.6 9 2 0 9 9 9 0 Leucine Rich Repeat ABC_membrane PF00664.23 CEG39052.1 - 1.6e-81 274.0 26.0 4.9e-45 154.3 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG39052.1 - 6.2e-54 182.2 0.0 7.9e-31 107.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEG39052.1 - 7.8e-11 41.8 5.4 0.0043 16.5 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CEG39052.1 - 2e-07 31.1 0.3 0.022 14.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CEG39052.1 - 7.7e-06 25.6 0.1 0.22 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG39052.1 - 6.8e-05 22.8 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CEG39052.1 - 0.0006 20.4 0.1 1.3 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CEG39052.1 - 0.0041 17.0 0.2 6.6 6.4 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 CEG39052.1 - 0.006 16.7 4.3 0.038 14.1 0.1 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain TsaE PF02367.17 CEG39052.1 - 0.0063 16.5 0.0 1.7 8.6 0.0 3.5 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 CEG39052.1 - 0.0073 16.4 4.4 0.55 10.3 0.2 3.2 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.6 CEG39052.1 - 0.011 16.0 0.7 3.4 7.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CEG39052.1 - 0.014 15.8 0.5 5.3 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 CEG39052.1 - 0.018 14.6 0.2 0.29 10.7 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 CEG39052.1 - 0.022 14.3 0.9 0.58 9.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEG39052.1 - 0.023 14.6 0.9 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 CEG39052.1 - 0.028 14.2 0.2 5 6.8 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 CEG39052.1 - 0.047 14.2 1.5 5.3 7.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 CEG39052.1 - 0.049 13.2 0.0 4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CEG39052.1 - 0.053 13.7 0.4 5.7 7.2 0.1 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CEG39052.1 - 0.063 12.5 0.1 3.4 6.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CEG39052.1 - 0.11 11.4 0.2 13 4.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 CEG39052.1 - 0.12 12.0 0.2 12 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain Pallilysin PF18663.1 CEG39052.1 - 0.13 12.2 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Pallilysin beta barrel domain AAA_33 PF13671.6 CEG39052.1 - 0.16 12.1 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TRP PF06011.12 CEG39055.1 - 1.3e-11 43.9 38.8 4.3e-11 42.2 33.1 2.4 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel ESR1_C PF12743.7 CEG39057.1 - 0.018 14.8 9.7 4.6 7.1 0.4 4.0 3 0 0 3 3 3 0 Oestrogen-type nuclear receptor final C-terminal Linker_histone PF00538.19 CEG39059.1 - 0.11 12.9 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 linker histone H1 and H5 family Methyltransf_16 PF10294.9 CEG39061.1 - 1.5e-17 63.9 0.0 2.1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG39061.1 - 0.00063 19.2 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEG39061.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MAM33 PF02330.16 CEG39062.1 - 3e-40 138.5 9.0 3.4e-40 138.2 9.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein GramPos_pilinD1 PF16555.5 CEG39062.1 - 0.11 12.7 0.7 0.16 12.1 0.7 1.4 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain TPR_1 PF00515.28 CEG39063.1 - 1.5e-21 75.2 1.5 1.2e-06 28.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39063.1 - 1.9e-18 65.0 3.0 0.00015 21.6 0.8 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39063.1 - 6.8e-15 54.5 1.7 6.8e-05 22.5 0.2 3.5 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.6 CEG39063.1 - 3e-13 48.8 1.9 0.00045 20.1 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 CEG39063.1 - 6.2e-11 42.1 21.6 1.2e-07 31.5 0.8 2.7 2 0 0 2 2 2 2 STI1 domain TPR_14 PF13428.6 CEG39063.1 - 4.5e-10 39.5 3.3 0.00088 19.9 0.2 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39063.1 - 1.3e-09 37.5 1.5 0.0016 18.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39063.1 - 1.8e-08 34.7 3.9 0.0034 17.9 0.1 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39063.1 - 4.1e-08 33.7 4.5 0.0025 18.4 1.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39063.1 - 2.4e-07 31.0 5.8 1.5e-05 25.2 0.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat SGT1 PF07093.11 CEG39063.1 - 0.0003 19.4 0.0 0.00044 18.8 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein TPR_17 PF13431.6 CEG39063.1 - 0.00035 20.7 0.1 0.76 10.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.11 CEG39063.1 - 0.0007 19.3 11.7 0.0059 16.3 4.3 3.0 2 1 1 3 3 3 2 XPC-binding domain TPR_10 PF13374.6 CEG39063.1 - 0.0012 18.7 11.7 0.71 9.8 0.5 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG39063.1 - 0.0077 16.4 0.9 0.22 11.7 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CEG39063.1 - 0.014 15.4 1.1 1.8 8.7 0.3 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CEG39063.1 - 0.038 14.2 0.5 0.097 12.9 0.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CEG39063.1 - 0.063 13.7 1.9 9.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain LAM_C PF12544.8 CEG39063.1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Lysine-2,3-aminomutase DUF3856 PF12968.7 CEG39063.1 - 0.092 12.8 1.5 11 6.1 0.2 3.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) GerD PF17898.1 CEG39063.1 - 0.11 12.4 7.0 0.059 13.3 4.3 1.9 2 0 0 2 2 2 0 Spore germination GerD central core domain TPR_6 PF13174.6 CEG39063.1 - 4 8.3 9.1 7 7.5 0.3 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat Syntaxin_2 PF14523.6 CEG39064.1 - 7.2e-15 55.2 3.0 7.2e-15 55.2 3.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 CEG39064.1 - 0.0013 18.4 8.1 0.0061 16.3 8.1 2.0 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CEG39064.1 - 0.0014 18.6 3.3 0.0084 16.1 3.3 2.5 1 1 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CEG39064.1 - 0.0039 16.9 0.4 0.0039 16.9 0.4 2.6 3 0 0 3 3 3 1 Synaptobrevin CorA PF01544.18 CEG39064.1 - 0.013 14.8 0.4 0.013 14.8 0.4 2.2 2 1 1 3 3 2 0 CorA-like Mg2+ transporter protein COG2 PF06148.11 CEG39064.1 - 0.018 15.1 3.9 1.5 8.9 0.3 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 B1 PF02246.15 CEG39064.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein L b1 domain RIX1 PF08167.12 CEG39064.1 - 0.12 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis PRMT5_C PF17286.2 CEG39064.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain AAA_13 PF13166.6 CEG39064.1 - 0.21 10.2 12.7 0.0087 14.8 2.8 2.0 1 1 1 2 2 2 0 AAA domain HisKA_3 PF07730.13 CEG39064.1 - 0.25 11.9 8.2 1.2 9.7 0.2 3.6 2 2 1 3 3 3 0 Histidine kinase BioT2 PF15368.6 CEG39064.1 - 0.32 10.9 2.4 2.6 8.0 0.3 2.5 2 1 1 3 3 3 0 Spermatogenesis family BioT2 Laminin_II PF06009.12 CEG39064.1 - 0.99 9.4 9.8 1.1 9.2 0.6 3.3 2 1 1 3 3 3 0 Laminin Domain II Nop25 PF09805.9 CEG39064.1 - 1.8 9.0 8.5 1.4 9.4 1.1 2.5 1 1 2 3 3 3 0 Nucleolar protein 12 (25kDa) Yuri_gagarin PF15934.5 CEG39064.1 - 3.3 7.5 12.0 0.67 9.7 0.4 2.8 2 1 1 3 3 3 0 Yuri gagarin DUF5344 PF17279.2 CEG39064.1 - 7.2 7.3 8.1 18 6.0 0.2 3.2 3 2 0 3 3 3 0 Family of unknown function (DUF5344) Sec34 PF04136.15 CEG39064.1 - 8.2 6.3 8.2 3.5 7.5 0.4 3.2 2 2 1 3 3 3 0 Sec34-like family Glyco_hydro_35 PF01301.19 CEG39065.1 - 7.5e-82 275.5 0.4 1e-81 275.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CEG39065.1 - 3.2e-07 30.9 0.3 0.029 14.9 0.2 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain GHD PF17834.1 CEG39065.1 - 4.4e-05 23.4 1.0 0.00023 21.2 0.0 2.4 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase IMP2_N PF18590.1 CEG39066.1 - 0.029 14.9 14.4 0.095 13.3 0.4 4.2 4 0 0 4 4 4 0 Immune Mapped Protein 2 (IMP2) N-terminal domain CSTF2_hinge PF14327.6 CEG39066.1 - 0.031 14.7 5.0 4.8 7.7 0.2 3.4 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 OrfB_IS605 PF01385.19 CEG39066.1 - 0.11 12.7 0.4 0.11 12.7 0.4 3.9 3 0 0 3 3 3 0 Probable transposase KRTDAP PF15200.6 CEG39067.1 - 0.026 14.3 0.3 0.062 13.1 0.3 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Glyco_hydro_8 PF01270.17 CEG39067.1 - 0.029 13.2 0.2 0.049 12.5 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 AAA_11 PF13086.6 CEG39067.1 - 0.034 13.9 0.6 0.034 13.9 0.6 2.1 2 0 0 2 2 2 0 AAA domain Vault_3 PF17795.1 CEG39068.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Major Vault Protein Repeat domain Homeobox_KN PF05920.11 CEG39069.1 - 5.8e-15 54.9 0.2 5.8e-15 54.9 0.2 2.1 2 1 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CEG39069.1 - 9.6e-11 41.4 2.0 2.2e-10 40.2 2.0 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CEG39069.1 - 0.0027 17.1 0.9 0.0053 16.2 0.1 1.9 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Alginate_lyase PF05426.12 CEG39069.1 - 0.006 16.2 0.6 0.0093 15.5 0.4 1.5 1 1 0 1 1 1 1 Alginate lyase Salp15 PF12115.8 CEG39069.1 - 0.078 13.4 1.1 1.5 9.3 0.2 2.3 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Laminin_G_3 PF13385.6 CEG39071.1 - 2.1e-14 53.9 1.8 5.2e-12 46.2 1.8 3.1 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 CEG39071.1 - 9.6e-06 25.4 0.2 0.00012 21.8 0.0 2.9 3 0 0 3 3 3 1 Pentaxin family Calx-beta PF03160.14 CEG39071.1 - 9.2e-05 22.6 0.1 0.00035 20.7 0.1 2.1 1 0 0 1 1 1 1 Calx-beta domain Laminin_B PF00052.18 CEG39071.1 - 0.00033 20.6 0.0 0.0009 19.2 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF2808 PF10989.8 CEG39071.1 - 0.00045 20.2 4.0 9.4 6.2 0.1 5.8 5 0 0 5 5 5 1 Protein of unknown function (DUF2808) Laminin_G_2 PF02210.24 CEG39071.1 - 0.063 13.9 0.0 0.79 10.3 0.0 2.8 2 0 0 2 2 2 0 Laminin G domain RRM_1 PF00076.22 CEG39072.1 - 8.3e-53 176.1 0.0 2.2e-20 72.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG39072.1 - 2e-07 31.0 0.0 0.73 10.0 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif OB_RNB PF08206.11 CEG39072.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Zip PF02535.22 CEG39073.1 - 2.8e-51 174.7 8.7 3.4e-51 174.5 8.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF5392 PF17370.2 CEG39073.1 - 0.0043 17.1 0.2 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5392) Claudin_2 PF13903.6 CEG39073.1 - 0.0071 16.1 2.5 0.36 10.6 0.7 2.5 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction Pyr_redox_2 PF07992.14 CEG39074.1 - 4.1e-66 223.2 2.6 6.8e-66 222.5 2.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG39074.1 - 5.9e-30 103.8 1.7 5.9e-30 103.8 1.7 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEG39074.1 - 5e-21 75.1 5.3 2.3e-18 66.5 0.2 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG39074.1 - 7.6e-17 61.5 3.6 4.3e-16 59.0 3.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEG39074.1 - 5.4e-08 32.3 6.2 9e-05 21.7 1.5 3.4 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 CEG39074.1 - 9e-07 28.6 1.0 6e-06 25.9 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG39074.1 - 9.8e-07 27.8 1.1 0.0056 15.4 0.8 2.5 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.6 CEG39074.1 - 0.0001 21.6 0.1 0.001 18.3 0.0 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CEG39074.1 - 0.00031 20.4 8.7 0.024 14.2 1.3 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 CEG39074.1 - 0.0011 18.1 0.3 0.0024 17.0 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CEG39074.1 - 0.0039 17.4 0.2 0.01 16.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEG39074.1 - 0.006 15.8 2.5 0.021 14.1 1.4 2.2 1 1 1 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CEG39074.1 - 0.0083 16.6 0.1 1.2 9.7 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 CEG39074.1 - 0.018 14.4 6.0 0.24 10.7 0.2 3.2 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 CEG39074.1 - 0.033 14.7 0.5 9.9 6.7 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 CEG39074.1 - 0.09 12.1 2.8 5.3 6.4 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CEG39074.1 - 0.098 13.3 3.2 10 6.7 0.2 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF2277 PF10041.9 CEG39074.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) 3HCDH_N PF02737.18 CEG39074.1 - 0.2 11.6 3.8 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3632 PF12311.8 CEG39075.1 - 1.2 9.6 6.3 0.18 12.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) DDE_1 PF03184.19 CEG39078.1 - 2.6e-11 43.5 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PCI PF01399.27 CEG39080.1 - 1.6e-17 63.9 1.7 4.9e-17 62.4 1.7 1.9 1 0 0 1 1 1 1 PCI domain mRNA_stabil PF13929.6 CEG39080.1 - 8.7e-06 24.9 5.8 1.3e-05 24.4 0.4 2.7 3 0 0 3 3 3 1 mRNA stabilisation TPR_14 PF13428.6 CEG39080.1 - 0.00015 22.2 0.8 2 9.4 0.3 5.0 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39080.1 - 0.00017 21.4 2.2 5.1 7.4 0.1 5.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39080.1 - 0.006 16.8 1.7 2 8.8 0.2 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39080.1 - 0.044 13.9 3.6 35 4.9 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39080.1 - 0.45 11.3 2.4 27 5.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 CEG39080.1 - 4.8 7.6 7.2 74 3.8 0.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 CEG39081.1 - 1.7e-23 83.1 42.0 1.4e-16 60.4 8.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG39081.1 - 7.2e-14 51.5 0.1 7.2e-14 51.5 0.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CEG39081.1 - 2.5e-08 32.7 16.1 2.7e-06 26.0 5.8 3.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family SLIDE PF09111.10 CEG39081.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 SLIDE Helicase_C_2 PF13307.6 CEG39082.1 - 5.6e-54 182.9 0.0 2.3e-53 180.9 0.0 2.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CEG39082.1 - 8.6e-46 155.8 3.0 8.6e-46 155.8 3.0 1.9 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CEG39082.1 - 0.0033 17.2 5.4 0.31 10.8 3.3 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF760 PF05542.11 CEG39082.1 - 0.39 11.1 2.4 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF760) ResIII PF04851.15 CEG39082.1 - 0.39 10.7 16.1 0.37 10.8 5.6 4.7 5 1 0 5 5 5 0 Type III restriction enzyme, res subunit Mod_r PF07200.13 CEG39082.1 - 2.1 8.5 22.7 0.42 10.7 10.0 4.1 4 0 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Spo12 PF05032.12 CEG39083.1 - 0.079 12.9 2.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Spo12 family DUF5523 PF17661.1 CEG39083.1 - 1.2 8.8 15.2 2.1 7.9 15.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Glyco_hydro_19 PF00182.19 CEG39084.1 - 3.5e-46 158.0 3.0 5.9e-45 154.0 3.0 2.2 1 1 0 1 1 1 1 Chitinase class I Baculo_p74 PF04583.12 CEG39086.1 - 0.2 11.1 1.2 0.25 10.8 1.2 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Lipid_DES PF08557.10 CEG39087.1 - 7.1e-19 67.0 1.6 1.2e-18 66.3 1.6 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 CEG39087.1 - 6.5e-12 45.8 4.0 6.5e-12 45.8 4.0 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Hydrolase_4 PF12146.8 CEG39089.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase_C PF00433.24 CEG39090.1 - 7.5e-06 26.6 2.0 1.4e-05 25.7 2.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.25 CEG39090.1 - 0.076 12.4 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Acetone_carb_G PF08882.11 CEG39090.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit RhoGAP PF00620.27 CEG39092.1 - 6e-16 58.6 0.0 9.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PBD PF00786.28 CEG39092.1 - 7.7e-05 23.0 0.1 0.00022 21.5 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Glycos_transf_1 PF00534.20 CEG39094.1 - 5.8e-07 29.2 0.0 2.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG39094.1 - 0.0032 17.9 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UCH_1 PF13423.6 CEG39096.1 - 4.9e-11 42.8 0.3 8.4e-11 42.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CEG39096.1 - 3.4e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PDZ PF00595.24 CEG39096.1 - 4.8e-05 23.6 0.1 9.3e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG39096.1 - 0.00029 20.6 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain zf-RanBP PF00641.18 CEG39096.1 - 0.0006 19.1 4.4 0.00065 19.0 1.9 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 CEG39096.1 - 0.34 11.0 4.8 1.9 8.6 0.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CEG39096.1 - 1.1 8.7 8.5 0.35 10.4 1.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain R3H PF01424.22 CEG39098.1 - 1.4e-10 41.0 1.8 2.6e-10 40.1 0.5 2.2 2 0 0 2 2 2 1 R3H domain zf-C3HC4_3 PF13920.6 CEG39098.1 - 1.9e-07 30.8 8.0 1.9e-07 30.8 8.0 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2HE PF16278.5 CEG39098.1 - 0.87 10.1 7.7 9.3 6.8 2.3 3.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C3HC4 PF00097.25 CEG39098.1 - 1.4 8.9 25.8 0.034 14.0 8.9 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF832 PF05734.11 CEG39099.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Flavokinase PF01687.17 CEG39100.1 - 2.3e-31 108.4 0.0 2.6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase EamA PF00892.20 CEG39101.1 - 4e-24 85.4 21.3 1.4e-13 51.2 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CEG39101.1 - 1.4e-08 34.4 10.0 1.3e-05 24.8 1.5 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family SLC35F PF06027.12 CEG39101.1 - 0.00034 20.2 10.8 0.0067 16.0 1.4 2.1 1 1 1 2 2 2 2 Solute carrier family 35 UAA PF08449.11 CEG39101.1 - 0.0028 16.9 2.5 0.0028 16.9 2.5 2.0 1 1 0 2 2 2 1 UAA transporter family DUF3040 PF11239.8 CEG39101.1 - 7.8 6.9 7.7 42 4.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Cpn60_TCP1 PF00118.24 CEG39102.1 - 5.3e-37 127.6 2.9 7e-37 127.2 2.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsJ PF01728.19 CEG39103.1 - 9.3e-66 221.3 0.2 1.1e-65 221.1 0.2 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CEG39103.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FYVE PF01363.21 CEG39104.1 - 1.8e-11 44.0 13.2 1.8e-11 44.0 13.2 3.6 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CEG39104.1 - 3.8e-11 43.1 4.0 3.8e-11 43.1 4.0 4.2 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 CEG39104.1 - 1.9e-10 40.3 1.4 1.9e-10 40.3 1.4 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEG39104.1 - 5.1e-08 32.8 0.3 5.1e-08 32.8 0.3 3.8 3 1 1 4 4 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG39104.1 - 6.4e-08 32.3 4.7 6.4e-08 32.3 4.7 4.7 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG39104.1 - 2.9e-07 30.3 3.7 2.9e-07 30.3 3.7 4.4 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEG39104.1 - 9.3e-06 25.4 4.8 9.3e-06 25.4 4.8 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG39104.1 - 0.00063 19.9 17.4 0.0032 17.6 4.6 4.8 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEG39104.1 - 0.00075 19.7 5.7 0.00075 19.7 5.7 3.4 3 2 1 4 4 2 1 RING-H2 zinc finger domain PHD PF00628.29 CEG39104.1 - 0.015 15.2 4.8 0.015 15.2 4.8 4.3 4 1 0 4 4 3 0 PHD-finger DZR PF12773.7 CEG39104.1 - 0.031 14.3 28.7 0.056 13.5 5.5 4.8 2 2 2 4 4 4 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CEG39104.1 - 3.9 7.7 27.7 0.13 12.4 0.8 5.7 4 1 0 4 4 4 0 Zinc ribbon domain Peptidase_M14 PF00246.24 CEG39105.1 - 3.8e-23 82.7 0.0 7.4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CEG39105.1 - 4.5e-06 26.0 0.6 1.2e-05 24.6 0.6 1.7 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family GTP_EFTU_D2 PF03144.25 CEG39106.1 - 0.086 13.2 1.6 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 2 FANCL_C PF11793.8 CEG39106.1 - 0.096 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Tricorn_C1 PF14684.6 CEG39106.1 - 0.22 11.6 3.7 0.56 10.3 0.1 3.2 3 1 1 4 4 4 0 Tricorn protease C1 domain DUF724 PF05266.14 CEG39106.1 - 2.1 8.1 26.3 1.4 8.7 6.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 CEG39106.1 - 8.5 6.9 30.7 0.4 11.2 8.2 3.8 2 2 0 2 2 2 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 CEG39106.1 - 9.8 6.3 38.7 0.77 9.9 9.5 4.0 2 2 2 4 4 4 0 Tropomyosin like ABC_membrane PF00664.23 CEG39107.1 - 9.7e-52 176.3 4.0 1.4e-51 175.8 4.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEG39107.1 - 4.9e-37 127.5 0.0 3.2e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CEG39107.1 - 3e-07 30.1 0.8 9.9e-06 25.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 CEG39107.1 - 0.00012 22.5 0.8 0.086 13.3 1.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CEG39107.1 - 0.008 15.0 0.3 0.052 12.3 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class APS_kinase PF01583.20 CEG39107.1 - 0.011 15.7 0.2 0.09 12.7 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 CEG39107.1 - 0.011 16.2 0.2 0.039 14.3 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEG39107.1 - 0.014 15.2 0.1 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 CEG39107.1 - 0.015 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CEG39107.1 - 0.035 13.4 0.1 0.1 11.8 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 CEG39107.1 - 0.044 13.0 0.2 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 CEG39107.1 - 0.045 13.0 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 CEG39107.1 - 0.051 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 CEG39107.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Aldo_ket_red PF00248.21 CEG39107.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family AAA_24 PF13479.6 CEG39107.1 - 0.075 12.8 0.5 0.14 11.9 0.5 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CEG39107.1 - 0.13 12.4 1.6 0.62 10.1 1.1 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 CEG39107.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEG39107.1 - 0.14 11.9 0.9 0.35 10.6 0.9 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEG39107.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG39107.1 - 0.15 12.3 1.4 4.2 7.7 1.4 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG39107.1 - 0.7 9.9 2.7 0.83 9.7 1.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain PPR_2 PF13041.6 CEG39108.1 - 2.5e-33 114.0 5.1 7.4e-11 42.1 0.1 7.7 4 1 4 8 8 8 5 PPR repeat family PPR_3 PF13812.6 CEG39108.1 - 5.8e-26 90.4 1.8 2.2e-10 40.5 0.6 4.7 2 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 CEG39108.1 - 7.1e-26 88.6 3.8 1.5e-07 31.2 0.1 8.7 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 CEG39108.1 - 4.3e-17 62.2 0.6 9.9e-11 41.4 0.1 3.5 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEG39108.1 - 1.2e-12 47.3 2.3 0.00058 19.5 0.0 5.3 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.6 CEG39108.1 - 0.00071 20.2 1.8 5.4 8.1 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Exog_C PF18026.1 CEG39108.1 - 0.11 12.5 0.1 9.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain MRP-S27 PF10037.9 CEG39108.1 - 0.18 10.6 0.3 1.1 8.0 0.3 2.0 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.17 CEG39108.1 - 8.8 6.7 5.8 27 5.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CEG39110.1 - 5.5e-30 104.6 19.1 1.2e-18 67.3 5.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG39110.1 - 2.1e-26 92.7 30.9 2.3e-24 86.0 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 CEG39110.1 - 0.04 12.1 0.2 0.04 12.1 0.2 2.4 2 1 0 2 2 2 0 BT1 family Biotin_lipoyl PF00364.22 CEG39115.1 - 8.4e-10 38.3 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEG39115.1 - 6.1e-06 26.0 0.0 0.0036 17.1 0.0 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 CEG39115.1 - 0.085 12.1 0.0 11 5.2 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Big_9 PF17963.1 CEG39116.1 - 2e-05 25.3 12.2 0.96 10.2 0.2 8.8 9 1 0 9 9 9 3 Bacterial Ig domain Cadherin_4 PF17803.1 CEG39116.1 - 3.1e-05 24.5 10.1 0.29 11.8 0.0 7.1 6 1 0 6 6 6 2 Bacterial cadherin-like domain DUF21 PF01595.20 CEG39117.1 - 1.9e-30 105.8 1.1 4.9e-30 104.5 1.0 1.7 1 1 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CEG39117.1 - 2.9e-07 30.8 1.4 0.00024 21.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain GNAT_acetyltr_2 PF13718.6 CEG39118.1 - 3.8e-97 324.1 0.0 2.8e-96 321.3 0.0 2.4 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CEG39118.1 - 3.2e-69 233.2 1.9 3.2e-69 233.2 1.9 2.5 4 0 0 4 4 4 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CEG39118.1 - 1.3e-61 207.5 0.1 4.4e-61 205.8 0.1 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 CEG39118.1 - 7.1e-33 112.4 0.1 2e-32 111.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CEG39118.1 - 0.00025 21.3 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain HlyIII PF03006.20 CEG39119.1 - 2.7e-52 177.7 20.1 4.5e-52 177.0 20.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related Jacalin PF01419.17 CEG39120.1 - 1.9e-36 124.9 5.1 1.1e-08 35.0 0.2 4.6 4 0 0 4 4 4 4 Jacalin-like lectin domain Prenyltrans PF00432.21 CEG39120.1 - 2.1 8.2 5.2 3.9 7.3 0.1 3.2 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat GalP_UDP_transf PF01087.22 CEG39121.1 - 0.11 13.0 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Jacalin PF01419.17 CEG39122.1 - 2.9e-11 43.4 1.4 1e-10 41.7 0.1 2.2 2 0 0 2 2 2 1 Jacalin-like lectin domain MS_channel PF00924.18 CEG39123.1 - 7.8e-13 48.4 0.3 1.8e-12 47.3 0.3 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 CEG39124.1 - 8.1e-15 54.9 0.1 1.8e-14 53.8 0.1 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel Adeno_E3B PF03376.14 CEG39124.1 - 0.19 12.0 0.3 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Adenovirus E3B protein ADK PF00406.22 CEG39125.1 - 1.4e-29 103.2 0.0 3.1e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG39125.1 - 6.6e-18 65.4 0.0 1.9e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG39125.1 - 1.2e-06 29.1 0.1 4.6e-06 27.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEG39125.1 - 1.3e-06 28.7 0.1 8.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG39125.1 - 3.3e-05 24.3 0.0 7.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG39125.1 - 0.00046 20.0 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CEG39125.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_5 PF07728.14 CEG39125.1 - 0.0035 17.3 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CEG39125.1 - 0.0037 17.8 0.2 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Thymidylate_kin PF02223.17 CEG39125.1 - 0.0039 16.9 0.1 2 8.0 0.0 2.8 3 0 0 3 3 3 1 Thymidylate kinase AAA_16 PF13191.6 CEG39125.1 - 0.0088 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CEG39125.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SKI PF01202.22 CEG39125.1 - 0.015 15.4 0.3 0.066 13.3 0.0 2.2 2 1 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.6 CEG39125.1 - 0.017 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEG39125.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CEG39125.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 CEG39125.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 CEG39125.1 - 0.056 13.7 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 CEG39125.1 - 0.075 13.3 0.1 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 CEG39125.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CEG39125.1 - 0.077 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.19 CEG39125.1 - 0.12 12.2 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 CEG39125.1 - 0.16 11.5 0.1 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF724 PF05266.14 CEG39126.1 - 7.9 6.3 16.6 0.041 13.7 2.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF724) CCDC74_C PF14917.6 CEG39126.1 - 9.5 6.8 15.2 0.46 11.0 0.3 3.9 5 0 0 5 5 5 0 Coiled coil protein 74, C terminal Ceramidase_alk PF04734.13 CEG39127.1 - 1.1e-138 463.1 0.0 2.2e-137 458.8 0.0 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CEG39127.1 - 8.9e-38 129.8 1.0 1.9e-37 128.7 0.1 1.9 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DEP PF00610.21 CEG39128.1 - 2.5e-21 75.5 0.1 9.5e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) B_solenoid_ydck PF18836.1 CEG39128.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK CC190 PF15768.5 CEG39128.1 - 0.14 12.2 3.6 0.24 11.5 3.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 BUD22 PF09073.10 CEG39128.1 - 1.9 7.7 8.7 3.1 7.0 8.7 1.2 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.24 CEG39129.1 - 3.7e-25 88.7 13.9 2.7e-15 56.2 1.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG39129.1 - 3.1e-24 85.6 13.9 1.5e-13 50.4 8.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily AATase PF07247.12 CEG39130.1 - 0.0026 16.4 0.3 0.033 12.7 0.3 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 CEG39130.1 - 0.035 12.8 0.1 0.056 12.1 0.1 1.2 1 0 0 1 1 1 0 Condensation domain PBECR2 PF18810.1 CEG39132.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Jacalin PF01419.17 CEG39133.1 - 1.9e-09 37.6 0.0 2.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF4123 PF13503.6 CEG39133.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) Jacalin PF01419.17 CEG39134.1 - 2.4e-08 34.0 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Jacalin-like lectin domain NAD_binding_6 PF08030.12 CEG39137.1 - 0.069 13.3 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Cupin_8 PF13621.6 CEG39140.1 - 1.1e-19 71.1 7.4 3e-19 69.7 7.4 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEG39140.1 - 5.6e-19 68.7 2.3 8.6e-17 61.6 0.6 2.7 2 0 0 2 2 2 2 JmjC domain, hydroxylase Trypsin PF00089.26 CEG39142.1 - 7.9e-34 117.4 0.1 9.1e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG39142.1 - 0.0023 18.8 0.1 0.0029 18.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG39143.1 - 2.3e-20 73.4 0.0 2.7e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin JTB PF05439.12 CEG39147.1 - 0.00034 20.6 1.5 0.0022 18.0 1.5 2.0 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) zf-C2H2_4 PF13894.6 CEG39148.1 - 6e-11 42.2 24.7 0.0035 18.1 2.7 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG39148.1 - 2.7e-07 30.7 23.1 0.026 15.0 0.4 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEG39148.1 - 3.7e-07 30.3 15.2 0.11 12.9 0.3 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CEG39148.1 - 0.00038 20.3 10.6 0.028 14.3 0.0 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 CEG39148.1 - 0.00056 20.6 5.3 0.0098 16.6 3.8 2.9 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CEG39148.1 - 0.0018 18.2 18.4 0.37 10.8 2.8 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-RING_11 PF17123.5 CEG39148.1 - 0.0028 17.3 3.4 1.9 8.3 0.2 3.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C2H2_2 PF12756.7 CEG39148.1 - 0.016 15.5 21.8 1.7 9.1 0.1 4.6 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CEG39148.1 - 0.052 14.0 15.7 0.56 10.7 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 CEG39148.1 - 0.098 12.8 8.6 11 6.2 0.1 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Rad50_zn_hook PF04423.14 CEG39148.1 - 0.12 12.2 2.5 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-met2 PF12907.7 CEG39148.1 - 0.22 11.7 10.0 3.7 7.8 0.1 4.4 4 0 0 4 4 4 0 Zinc-binding zf-C2H2_8 PF15909.5 CEG39148.1 - 0.41 11.0 3.8 2.2 8.6 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 CEG39148.1 - 0.75 9.5 10.9 3.7 7.3 0.8 2.9 2 2 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CEG39148.1 - 0.85 10.2 13.5 8.6 7.0 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain OrsD PF12013.8 CEG39148.1 - 1 9.8 11.6 1.6 9.2 6.0 3.0 3 1 0 3 3 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_UBZ PF18439.1 CEG39148.1 - 1.4 8.6 14.5 5.6 6.7 0.2 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 CEG39148.1 - 1.4 8.8 4.5 5.5 6.9 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Elf1 PF05129.13 CEG39148.1 - 2.3 8.3 11.1 4.1 7.5 2.1 3.4 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.6 CEG39148.1 - 4.3 7.4 11.0 11 6.0 0.1 3.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CEG39148.1 - 8.3 6.8 10.8 9 6.7 0.2 3.9 4 0 0 4 4 4 0 Ring finger domain p450 PF00067.22 CEG39149.1 - 1e-41 143.2 2.7 3.9e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 Stc1 PF12898.7 CEG39149.1 - 0.00036 21.0 1.8 0.00036 21.0 1.8 3.6 4 0 0 4 4 4 1 Stc1 domain zinc_ribbon_15 PF17032.5 CEG39149.1 - 0.078 13.7 5.5 1.2 9.9 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon family VASt PF16016.5 CEG39150.1 - 3.2e-26 92.6 0.0 7.6e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain FYVE PF01363.21 CEG39150.1 - 4.4e-12 45.9 7.3 1e-11 44.8 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 CEG39150.1 - 2.5e-07 30.6 0.2 6.6e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 GRAM domain IBR PF01485.21 CEG39150.1 - 0.019 15.2 1.5 0.057 13.6 1.5 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CEG39150.1 - 0.94 9.7 4.2 3 8.1 4.2 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-AN1 PF01428.16 CEG39150.1 - 1.4 9.1 6.8 3.3 7.9 6.8 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger Choline_transpo PF04515.12 CEG39151.1 - 3.2e-62 210.6 36.6 3.2e-62 210.6 36.6 2.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter IncF PF17626.2 CEG39151.1 - 0.38 11.1 13.9 0.61 10.5 0.4 2.9 3 0 0 3 3 3 0 Inclusion membrane protein F Spo7 PF03907.13 CEG39151.1 - 6 6.3 9.0 24 4.3 0.2 2.7 2 1 1 3 3 3 0 Spo7-like protein Trypsin PF00089.26 CEG39152.1 - 1.1e-31 110.4 0.1 1.1e-31 110.4 0.1 1.6 2 0 0 2 2 2 1 Trypsin Trypsin PF00089.26 CEG39153.1 - 1.8e-13 50.8 0.0 2.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin CXCR4_N PF12109.8 CEG39153.1 - 0.11 12.7 0.4 0.26 11.5 0.4 1.6 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Trypsin PF00089.26 CEG39155.1 - 5.8e-18 65.5 0.0 6.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CEG39155.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 CEG39157.1 - 1.3e-40 139.5 0.5 1.5e-40 139.4 0.5 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG39157.1 - 0.01 16.7 0.0 0.022 15.6 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 CEG39159.1 - 2.6e-35 122.3 0.0 2.9e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CEG39159.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 CEG39160.1 - 4e-40 138.0 0.1 4.5e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG39160.1 - 0.00017 22.5 0.2 0.00028 21.8 0.2 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_M24 PF00557.24 CEG39161.1 - 8.5e-44 149.7 0.0 1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 tRNA_bind PF01588.20 CEG39162.1 - 9.4e-17 60.9 0.4 9.1e-16 57.8 0.4 2.2 2 0 0 2 2 2 1 Putative tRNA binding domain DUF2439 PF10382.9 CEG39162.1 - 6.2e-12 45.7 2.6 6.5e-11 42.4 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) AMP-binding PF00501.28 CEG39163.1 - 2.4e-33 115.4 0.0 1.6e-32 112.7 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 CEG39163.1 - 5.5e-30 103.1 0.0 2.1e-07 31.2 0.0 8.0 9 0 0 9 9 9 5 PQQ-like domain PQQ_2 PF13360.6 CEG39163.1 - 8.1e-21 74.7 0.0 1.1e-10 41.5 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 CEG39163.1 - 6.4e-20 70.1 2.7 1.1e-06 28.2 0.0 7.4 8 0 0 8 8 8 3 PQQ enzyme repeat PP-binding PF00550.25 CEG39163.1 - 8.1e-06 26.1 1.4 1.8e-05 25.0 1.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site CsiD PF08943.10 CEG39163.1 - 0.12 11.4 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 CsiD FYVE PF01363.21 CEG39164.1 - 3.1e-11 43.2 15.6 9.6e-11 41.7 15.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger eIF-3_zeta PF05091.12 CEG39165.1 - 6.5e-182 606.1 0.0 7.4e-182 605.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Retrotran_gag_2 PF14223.6 CEG39168.1 - 3.6e-25 88.2 2.6 5e-25 87.8 2.6 1.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG39168.1 - 0.006 16.6 1.9 0.01 15.9 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.14 CEG39169.1 - 4.7e-20 72.3 0.0 6.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyltransferase PF01553.21 CEG39170.1 - 3.9e-16 58.9 0.0 9.3e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Methyltransf_5 PF01795.19 CEG39171.1 - 1.9e-89 300.3 2.2 2e-88 296.9 2.2 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 CEG39171.1 - 0.00023 21.8 0.1 0.0016 19.1 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG39171.1 - 0.00033 20.5 0.2 0.0012 18.7 0.2 1.9 2 1 0 2 2 2 1 Methyltransferase domain Sulfotransfer_3 PF13469.6 CEG39171.1 - 0.0037 17.7 0.1 0.032 14.6 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family Methyltransf_12 PF08242.12 CEG39171.1 - 0.0072 17.0 0.1 0.71 10.7 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 CEG39171.1 - 0.032 13.8 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DHHC PF01529.20 CEG39172.1 - 3.3e-25 88.7 9.3 3.3e-25 88.7 9.3 3.0 2 2 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CEG39172.1 - 5.8e-20 71.7 8.3 2.2e-09 37.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG39172.1 - 5.1e-19 68.4 3.6 7.1e-07 29.7 0.0 6.0 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG39172.1 - 2.7e-16 58.0 0.2 0.014 15.9 0.0 6.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CEG39172.1 - 1.2e-12 47.7 1.0 0.022 15.2 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 CEG39172.1 - 2e-11 43.9 5.0 0.00048 20.4 1.2 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) PHF5 PF03660.14 CEG39172.1 - 0.17 12.1 3.1 1.3 9.2 0.4 2.4 2 0 0 2 2 2 0 PHF5-like protein WEMBL PF05701.11 CEG39173.1 - 0.053 12.2 3.6 0.067 11.9 3.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Occludin_ELL PF07303.13 CEG39173.1 - 0.13 13.0 0.7 0.21 12.3 0.2 1.6 2 0 0 2 2 2 0 Occludin homology domain Lipl32 PF12103.8 CEG39174.1 - 0.092 12.4 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order PPR PF01535.20 CEG39178.1 - 3.8e-06 26.8 0.3 1.9 8.9 0.0 3.7 4 0 0 4 4 4 3 PPR repeat PPR_2 PF13041.6 CEG39178.1 - 0.00011 22.3 0.0 1.6 9.0 0.0 3.5 2 1 1 3 3 3 3 PPR repeat family PPR_long PF17177.4 CEG39178.1 - 0.0033 16.8 1.9 0.021 14.2 0.8 2.4 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP DRE2_N PF16803.5 CEG39178.1 - 0.015 15.5 0.5 0.83 9.9 0.1 2.4 2 1 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus SIX1_SD PF16878.5 CEG39178.1 - 0.026 15.1 0.1 0.053 14.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain His_Phos_2 PF00328.22 CEG39179.1 - 1.9e-16 60.4 0.1 3.6e-16 59.5 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Darcynin PF17074.5 CEG39179.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Darcynin, domain of unknown function LPP PF04728.13 CEG39180.1 - 0.0015 18.9 0.9 0.0015 18.9 0.9 2.6 3 1 0 3 3 3 1 Lipoprotein leucine-zipper DUF4686 PF15742.5 CEG39180.1 - 0.029 13.5 24.1 0.032 13.4 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) HIP1_clath_bdg PF16515.5 CEG39180.1 - 0.036 14.7 7.6 0.036 14.7 7.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0231 PF06062.11 CEG39180.1 - 0.12 12.6 9.0 0.13 12.5 7.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0231) DUF2730 PF10805.8 CEG39180.1 - 0.46 10.6 10.1 0.12 12.5 6.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 CEG39180.1 - 8.3 4.2 14.9 9.1 4.0 14.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fimbrial PF00419.20 CEG39181.1 - 0.023 15.0 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Fimbrial protein GRP PF07172.11 CEG39182.1 - 0.0069 17.0 10.1 0.009 16.7 10.1 1.1 1 0 0 1 1 1 1 Glycine rich protein family Glycos_transf_N PF04413.16 CEG39183.1 - 2.7e-47 160.7 0.0 5.3e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) GDPD PF03009.17 CEG39184.1 - 2.5e-49 168.3 0.0 1.1e-48 166.3 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 CEG39184.1 - 8.5e-15 54.4 0.1 2.5e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain cNMP_binding PF00027.29 CEG39184.1 - 1.5e-06 28.2 0.0 5.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain F5_F8_type_C PF00754.25 CEG39184.1 - 6.1e-05 23.1 0.6 0.072 13.2 0.2 3.2 3 0 0 3 3 3 2 F5/8 type C domain DnaJ PF00226.31 CEG39186.1 - 5e-14 52.2 0.9 4.1e-13 49.2 0.9 2.4 1 1 0 1 1 1 1 DnaJ domain DUF349 PF03993.12 CEG39186.1 - 0.06 13.6 3.7 5.3 7.4 0.1 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Mito_carr PF00153.27 CEG39187.1 - 2.3e-32 110.8 1.3 6.9e-21 74.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AMP-binding PF00501.28 CEG39189.1 - 9.7e-18 64.0 0.2 1.6e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TrkA_N PF02254.18 CEG39189.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HAV_VP PF12944.7 CEG39189.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP Glyco_transf_20 PF00982.21 CEG39190.1 - 0.033 12.9 0.5 0.038 12.7 0.5 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 20 HSP90 PF00183.18 CEG39191.1 - 1.5e-195 651.0 24.3 2e-195 650.6 24.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CEG39191.1 - 7.2e-14 52.2 0.1 1.9e-13 50.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEG39191.1 - 1.6e-10 41.0 0.1 1e-09 38.3 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3456 PF11938.8 CEG39192.1 - 1.7e-13 51.4 5.3 2.5e-08 34.6 2.3 2.1 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.15 CEG39192.1 - 0.0032 17.5 1.4 0.31 11.1 0.0 2.5 2 0 0 2 2 2 2 Saposin-like type B, region 1 Herpes_teg_N PF04843.12 CEG39192.1 - 0.045 13.5 0.1 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region AbiEi_3 PF11459.8 CEG39192.1 - 0.097 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Evr1_Alr PF04777.13 CEG39193.1 - 2.1e-26 92.3 0.5 3e-26 91.8 0.5 1.2 1 0 0 1 1 1 1 Erv1 / Alr family TPR_12 PF13424.6 CEG39194.1 - 4.1e-16 59.0 15.6 4.1e-07 30.2 2.1 4.1 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39194.1 - 1.1e-14 53.5 8.9 1.7e-05 24.4 0.0 5.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39194.1 - 5.5e-14 51.1 6.5 0.00021 21.1 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39194.1 - 2.2e-11 43.0 1.2 0.091 13.0 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39194.1 - 5.6e-10 38.5 17.4 0.019 14.9 0.3 6.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG39194.1 - 2.9e-05 23.6 5.8 4.8e-05 22.9 5.8 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 CEG39194.1 - 4.8e-05 23.1 11.6 0.0041 16.9 0.3 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39194.1 - 0.0027 18.3 10.0 0.73 10.5 1.5 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39194.1 - 0.0036 18.0 5.1 9.5 7.3 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat CooC_C PF15976.5 CEG39194.1 - 0.0099 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 CS1-pili formation C-terminal RPN7 PF10602.9 CEG39194.1 - 0.046 13.4 0.5 0.92 9.2 0.0 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 CEG39194.1 - 0.14 12.6 3.3 56 4.4 0.0 4.4 5 1 0 5 5 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CEG39194.1 - 0.21 11.7 2.4 12 6.0 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 CEG39194.1 - 0.78 9.5 4.4 3.1 7.6 0.2 3.7 3 1 1 4 4 4 0 TPR repeat TPR_4 PF07721.14 CEG39194.1 - 2.3 9.1 0.0 2.3 9.1 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_hydro_32N PF00251.20 CEG39196.1 - 1.3e-32 113.6 1.8 2.2e-32 112.8 1.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BNR_2 PF13088.6 CEG39196.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 BNR repeat-like domain BNR PF02012.20 CEG39196.1 - 0.11 12.6 0.2 0.52 10.5 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat RRM_1 PF00076.22 CEG39197.1 - 2.7e-24 84.8 0.1 7.9e-24 83.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CEG39197.1 - 6.8e-08 32.9 0.4 6.8e-08 32.9 0.4 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 CEG39197.1 - 0.0018 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif CSTF_C PF14304.6 CEG39197.1 - 0.022 14.4 1.4 0.051 13.2 1.4 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CEG39197.1 - 0.043 13.7 0.0 0.096 12.6 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CEG39197.1 - 0.21 11.4 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Ebp2 PF05890.12 CEG39198.1 - 1.2e-70 238.1 25.6 1.7e-70 237.7 25.6 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Lys-AminoMut_A PF09043.11 CEG39198.1 - 0.041 12.3 1.8 0.059 11.8 1.8 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Rgp1 PF08737.10 CEG39198.1 - 0.79 8.8 15.8 0.43 9.7 7.1 2.1 2 0 0 2 2 2 0 Rgp1 DUF5600 PF18150.1 CEG39199.1 - 1.5e-26 93.1 0.4 3.7e-26 91.8 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CEG39199.1 - 1.1e-16 61.3 0.0 5.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Dynamin family EHD_N PF16880.5 CEG39199.1 - 5e-15 55.1 1.7 9e-15 54.3 1.7 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 CEG39199.1 - 1.1e-09 38.3 0.0 2.8e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.7 CEG39199.1 - 1e-08 35.0 0.0 3.1e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Roc PF08477.13 CEG39199.1 - 0.00019 21.6 0.0 0.9 9.8 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEG39199.1 - 0.0025 17.4 0.0 0.0072 15.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CEG39199.1 - 0.034 13.7 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B EF-hand_6 PF13405.6 CEG39199.1 - 0.039 13.9 0.0 0.17 11.9 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CEG39199.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 EF hand OTU PF02338.19 CEG39200.1 - 1.1e-12 48.5 0.0 2.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEG39200.1 - 2.7e-07 30.3 0.0 0.00054 19.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain PAP_central PF04928.17 CEG39202.1 - 2.2e-67 226.7 0.1 4.2e-67 225.7 0.1 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEG39202.1 - 3.3e-07 30.1 1.3 9.7e-06 25.3 0.0 3.0 4 0 0 4 4 4 1 Poly(A) polymerase predicted RNA binding domain Abhydrolase_2 PF02230.16 CEG39203.1 - 0.00081 19.3 0.0 0.00095 19.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Glyco_hydro_19 PF00182.19 CEG39205.1 - 5.4e-30 105.0 1.5 1.5e-29 103.6 1.5 1.6 1 1 0 1 1 1 1 Chitinase class I Syntaxin-6_N PF09177.11 CEG39207.1 - 1.3 9.6 8.4 0.44 11.1 0.5 3.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Palm_thioest PF02089.15 CEG39210.1 - 1e-77 261.3 0.0 1.3e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PNRC PF15365.6 CEG39210.1 - 3.9e-08 32.9 3.2 1.2e-07 31.3 3.2 1.9 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif DUF676 PF05057.14 CEG39210.1 - 0.073 12.6 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Pro_isomerase PF00160.21 CEG39211.1 - 5e-36 124.4 0.1 6.1e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ICL PF00463.21 CEG39212.1 - 4.8e-212 705.1 0.1 7.3e-212 704.5 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CEG39212.1 - 6.6e-13 48.7 0.3 2.7e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FYVE PF01363.21 CEG39216.1 - 3e-12 46.5 16.7 3e-12 46.5 16.7 2.1 2 0 0 2 2 2 1 FYVE zinc finger PRR18 PF15671.5 CEG39216.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 FYVE_2 PF02318.16 CEG39216.1 - 0.53 10.5 15.6 2.2 8.5 15.6 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger IMPDH PF00478.25 CEG39218.1 - 8.7e-133 442.6 3.8 1e-132 442.4 3.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CEG39218.1 - 1.2e-14 54.5 0.2 1e-07 32.2 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 CEG39218.1 - 1.6e-09 37.7 0.8 2.2e-07 30.6 0.9 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CEG39218.1 - 1.7e-09 37.2 0.8 3.3e-09 36.2 0.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CEG39218.1 - 2e-05 24.2 1.9 8.9e-05 22.1 1.8 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CEG39218.1 - 0.00091 18.6 1.2 0.0018 17.6 0.6 1.9 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 CEG39218.1 - 0.0091 15.2 1.0 0.1 11.8 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF561) NanE PF04131.14 CEG39218.1 - 0.011 14.9 0.7 0.041 13.1 0.7 2.0 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 CEG39218.1 - 0.061 12.5 1.9 0.071 12.3 0.5 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PH PF00169.29 CEG39219.1 - 1.2e-43 147.9 3.2 5.4e-14 52.6 0.1 3.5 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 CEG39219.1 - 6.6e-15 55.4 15.5 2.4e-07 31.1 0.2 5.4 3 3 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 CEG39219.1 - 1.2e-13 51.2 4.5 1.4e-05 25.2 0.4 4.1 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.6 CEG39219.1 - 2.3e-09 37.3 0.4 0.0075 16.4 0.1 3.5 4 0 0 4 4 4 2 PH domain PH_9 PF15410.6 CEG39219.1 - 3.8e-05 24.0 6.1 0.14 12.5 0.3 5.4 3 3 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.6 CEG39219.1 - 0.0034 17.2 1.0 0.031 14.1 0.1 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 CEG39219.1 - 0.12 12.7 0.1 30 5.0 0.0 3.1 3 0 0 3 3 3 0 Plant pleckstrin homology-like region PLDc_2 PF13091.6 CEG39220.1 - 1.1e-17 64.2 0.0 8.2e-11 41.9 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEG39220.1 - 7e-17 60.8 2.9 2.7e-08 33.6 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-RING_2 PF13639.6 CEG39221.1 - 2e-12 47.2 3.3 3.9e-12 46.3 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG39221.1 - 1.6e-09 37.9 7.1 4.6e-09 36.4 7.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG39221.1 - 2.4e-09 36.7 1.4 5e-09 35.7 1.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEG39221.1 - 5.5e-08 32.5 1.7 1.4e-07 31.3 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG39221.1 - 5.8e-08 32.4 3.2 1.3e-07 31.3 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG39221.1 - 3.8e-07 30.0 1.2 7e-07 29.1 1.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG39221.1 - 5.4e-06 26.2 3.5 9.9e-06 25.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG39221.1 - 6.7e-06 26.1 2.4 1.3e-05 25.1 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEG39221.1 - 6.5e-05 22.6 0.5 0.00013 21.7 0.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CEG39221.1 - 0.00022 21.2 2.9 0.00046 20.2 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG39221.1 - 0.00052 19.8 3.0 0.0011 18.7 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG39221.1 - 0.012 15.7 3.3 0.012 15.7 3.3 2.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 CEG39221.1 - 0.054 13.6 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_17 PF17120.5 CEG39221.1 - 1.2 8.8 5.9 3.3 7.4 5.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type MTS PF05175.14 CEG39223.1 - 6.7e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CEG39223.1 - 0.00028 20.8 0.0 0.00065 19.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG39223.1 - 0.00031 21.4 0.0 0.0014 19.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 CEG39223.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 N6_Mtase PF02384.16 CEG39223.1 - 0.003 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 CEG39223.1 - 0.0033 18.0 0.0 0.009 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CEG39223.1 - 0.0056 15.8 0.0 0.0076 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.18 CEG39223.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EcoRI_methylase PF13651.6 CEG39223.1 - 0.063 12.5 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Methyltransf_12 PF08242.12 CEG39223.1 - 0.065 14.0 0.0 0.21 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Eco57I PF07669.11 CEG39223.1 - 0.071 13.6 0.0 0.65 10.5 0.0 2.4 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Na_Ca_ex PF01699.24 CEG39225.1 - 2.3e-41 141.3 37.8 7.1e-21 74.7 12.0 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DHOase PF12890.7 CEG39226.1 - 0.048 13.6 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Dihydro-orotase-like TPR_2 PF07719.17 CEG39227.1 - 2.6e-08 33.3 10.4 0.002 18.1 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39227.1 - 9.3e-07 28.4 1.2 0.0057 16.3 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 CEG39227.1 - 2.2e-06 28.0 6.7 0.0037 18.0 1.4 4.3 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39227.1 - 5e-06 26.1 7.6 0.0021 17.8 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39227.1 - 1.4e-05 25.6 6.8 0.022 15.4 1.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39227.1 - 9.1e-05 22.6 4.0 1.2 9.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39227.1 - 0.00012 22.5 8.1 0.025 15.1 0.7 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39227.1 - 0.0012 18.8 4.5 0.16 12.3 0.2 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CEG39227.1 - 0.0016 18.9 0.5 0.48 10.9 0.0 2.3 1 1 1 2 2 2 2 Alkyl sulfatase dimerisation DUF5588 PF17826.1 CEG39227.1 - 0.0025 16.8 0.1 0.23 10.3 0.0 2.2 1 1 1 2 2 2 1 Family of unknown function (DUF5588) TPR_9 PF13371.6 CEG39227.1 - 0.0042 17.2 2.4 0.11 12.6 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CEG39227.1 - 0.015 14.9 0.3 0.037 13.7 0.3 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 CEG39227.1 - 0.028 15.1 3.0 8.8 7.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39227.1 - 0.053 13.6 5.9 7.5 6.8 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat HSP70 PF00012.20 CEG39228.1 - 9.3e-100 334.5 0.0 2.4e-99 333.2 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG39228.1 - 1.8e-12 46.8 0.0 2.7e-10 39.6 0.0 2.9 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CEG39228.1 - 0.047 14.1 0.2 16 6.0 0.1 3.2 3 1 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 CEG39228.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein NLE PF08154.12 CEG39228.1 - 0.11 13.0 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 NLE (NUC135) domain ACC_central PF08326.12 CEG39230.1 - 0.076 11.2 0.1 0.073 11.3 0.1 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region TGF_beta_GS PF08515.12 CEG39230.1 - 0.55 9.8 2.4 1 8.9 2.4 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif NYD-SP28_assoc PF14775.6 CEG39231.1 - 0.017 15.2 0.9 0.83 9.8 1.0 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain SpoIISA_toxin PF14171.6 CEG39233.1 - 0.095 12.4 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Mrpl_C PF18502.1 CEG39233.1 - 0.42 10.9 3.2 0.5 10.7 0.8 2.1 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain DUF4042 PF13251.6 CEG39233.1 - 0.42 10.3 4.2 2.2 8.0 1.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4042) NPR3 PF03666.13 CEG39236.1 - 1.2e-43 149.6 7.3 2.8e-23 82.5 3.1 3.7 2 1 2 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CEG39236.1 - 0.0024 16.7 0.0 1.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Nitrogen permease regulator 2 HTH_IclR PF09339.10 CEG39236.1 - 0.08 12.8 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain ArfGap PF01412.18 CEG39237.1 - 1.9e-40 137.6 0.1 1.9e-40 137.6 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf EOS1 PF12326.8 CEG39237.1 - 0.23 11.4 0.3 2.1 8.3 0.0 2.0 2 0 0 2 2 2 0 N-glycosylation protein BORG_CEP PF14957.6 CEG39237.1 - 0.82 10.8 5.9 3.3 8.9 0.8 2.5 2 0 0 2 2 2 0 Cdc42 effector Neur_chan_memb PF02932.16 CEG39237.1 - 1 9.4 7.1 0.36 10.9 2.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CEG39237.1 - 1.3 7.7 10.6 0.8 8.4 4.4 2.1 2 0 0 2 2 2 0 Presenilin FKBP_N PF01346.18 CEG39237.1 - 3.6 8.6 14.7 48 5.0 11.8 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Spore_YhcN_YlaJ PF09580.10 CEG39237.1 - 8 6.5 13.8 0.74 9.9 8.6 1.9 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Med19 PF10278.9 CEG39237.1 - 9.7 6.1 19.1 1.7 8.6 6.1 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 HET-S PF17108.5 CEG39238.1 - 0.57 10.0 2.7 1.2 9.0 2.7 1.6 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic DUF4404 PF14357.6 CEG39238.1 - 8.1 7.2 7.2 36 5.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) DUF5062 PF16691.5 CEG39241.1 - 0.21 11.7 6.7 2.5 8.3 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5062) RBB1NT PF08169.11 CEG39241.1 - 0.23 11.6 3.8 2.9 8.1 0.5 2.3 1 1 1 2 2 2 0 RBB1NT (NUC162) domain Caskin-tail PF16632.5 CEG39241.1 - 0.53 10.7 5.6 0.5 10.8 0.8 2.2 1 1 0 2 2 2 0 C-terminal region of Caskin Inhibitor_I69 PF13734.6 CEG39241.1 - 1.5 9.3 6.9 0.47 10.9 0.8 2.2 1 1 1 2 2 2 0 Spi protease inhibitor DUF4297 PF14130.6 CEG39242.1 - 0.0011 19.2 1.1 0.0013 18.9 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4297) SNARE PF05739.19 CEG39242.1 - 0.061 13.3 1.0 0.11 12.5 0.7 1.6 1 1 1 2 2 2 0 SNARE domain PDZ PF00595.24 CEG39243.1 - 2.1e-05 24.8 0.0 0.023 15.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CEG39243.1 - 0.00052 19.8 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CEG39243.1 - 0.047 14.0 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain IQ PF00612.27 CEG39243.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pkinase_Tyr PF07714.17 CEG39247.1 - 1.3e-13 50.8 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG39247.1 - 1.5e-09 37.7 0.0 2.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Exog_C PF18026.1 CEG39247.1 - 0.032 14.3 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Pkinase PF00069.25 CEG39248.1 - 3.3e-17 62.7 0.0 3.7e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39248.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Cu-binding_MopE PF11617.8 CEG39248.1 - 0.041 14.0 1.4 0.055 13.7 0.4 1.7 2 0 0 2 2 2 0 Putative metal-binding motif p47_phox_C PF08944.11 CEG39249.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Ion_trans PF00520.31 CEG39250.1 - 3e-19 69.2 9.1 3.9e-19 68.8 9.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEG39250.1 - 1.5e-11 44.1 7.4 1.5e-11 44.1 7.4 2.1 2 0 0 2 2 2 1 Ion channel Glyco_transf_20 PF00982.21 CEG39251.1 - 2.5e-146 488.1 0.0 1.8e-95 320.4 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG39251.1 - 7.3e-42 143.1 0.0 1.5e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase FlxA PF14282.6 CEG39251.1 - 0.047 13.7 4.4 0.2 11.7 4.4 2.1 1 0 0 1 1 1 0 FlxA-like protein DDE_Tnp_1_4 PF13701.6 CEG39251.1 - 0.081 11.2 0.1 0.14 10.4 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain group 1 Glyco_hydro_18 PF00704.28 CEG39252.1 - 1.9e-09 37.7 0.0 3.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.32 CEG39257.1 - 2.5e-16 59.8 17.0 5e-05 24.0 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CEG39257.1 - 8.6e-15 54.8 0.1 1.4e-13 50.9 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CEG39257.1 - 9.4e-08 32.3 0.5 0.027 14.8 0.1 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG39257.1 - 3.1e-05 23.9 0.1 5.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CEG39257.1 - 0.18 9.8 0.2 2.6 5.9 0.1 2.0 1 1 1 2 2 2 0 IKI3 family PX PF00787.24 CEG39258.1 - 0.022 14.8 0.1 0.064 13.2 0.1 1.8 1 0 0 1 1 1 0 PX domain ASH PF15780.5 CEG39259.1 - 1.7e-08 34.6 11.7 0.0042 17.3 0.1 9.0 10 0 0 10 10 10 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CEG39259.1 - 0.0012 18.9 7.1 0.97 9.5 0.8 6.7 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) DUF1640 PF07798.11 CEG39259.1 - 0.17 12.0 1.1 0.43 10.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) JAB PF01398.21 CEG39260.1 - 6e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEG39260.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain CSN5_C PF18323.1 CEG39260.1 - 0.11 13.4 0.1 0.21 12.6 0.1 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain FHA PF00498.26 CEG39261.1 - 1.2e-10 41.6 0.2 2.3e-10 40.6 0.2 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG39261.1 - 0.043 14.1 0.0 0.62 10.4 0.0 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 CEG39261.1 - 0.048 13.5 1.4 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain BCLP PF12304.8 CEG39261.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Beta-casein like protein U3_snoRNA_assoc PF08297.11 CEG39261.1 - 0.34 11.7 2.2 0.82 10.4 2.2 1.6 1 0 0 1 1 1 0 U3 snoRNA associated HEPN_LA2681 PF18733.1 CEG39262.1 - 0.045 13.0 0.0 0.046 13.0 0.0 1.0 1 0 0 1 1 1 0 LA2681-like HEPN FAD_binding_5 PF00941.21 CEG39262.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase UCH PF00443.29 CEG39263.1 - 1.2e-27 97.0 0.0 1.3e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG39263.1 - 0.00021 21.0 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4294 PF14127.6 CEG39269.1 - 0.00099 19.1 0.9 0.00099 19.1 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4294) PAP_central PF04928.17 CEG39270.1 - 3.1e-69 232.7 0.0 5.1e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEG39270.1 - 6.2e-07 29.2 0.0 2.1e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap_D2 PF17403.2 CEG39270.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DS PF01916.17 CEG39270.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase zf-CCHC PF00098.23 CEG39273.1 - 0.00015 21.7 5.0 0.00015 21.7 5.0 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEG39273.1 - 0.076 12.8 1.3 0.13 12.0 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle SOG2 PF10428.9 CEG39273.1 - 0.43 9.7 5.3 0.47 9.6 5.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein MAJIN PF15077.6 CEG39273.1 - 0.99 9.2 8.0 0.99 9.1 8.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4834 PF16118.5 CEG39273.1 - 7.2 7.6 10.2 11 7.1 10.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SWIM PF04434.17 CEG39275.1 - 9.1e-05 22.0 0.2 0.00014 21.4 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF1765 PF08578.10 CEG39279.1 - 2.5e-20 73.2 0.7 4.9e-20 72.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Pkinase PF00069.25 CEG39281.1 - 1.1e-47 162.7 0.0 9.3e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39281.1 - 4.1e-21 75.4 0.0 7.5e-20 71.3 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG39281.1 - 0.00095 18.6 0.0 1.2 8.3 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 CEG39281.1 - 0.0091 15.9 0.1 0.033 14.1 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG39281.1 - 0.041 13.2 0.0 0.089 12.1 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEG39281.1 - 0.066 12.0 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF4235 PF14019.6 CEG39282.1 - 0.11 12.6 0.2 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) TruD PF01142.18 CEG39283.1 - 1.8e-70 237.9 0.3 3.8e-65 220.3 0.0 2.4 2 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) Peptidase_C25 PF01364.18 CEG39283.1 - 0.039 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25 Mito_carr PF00153.27 CEG39284.1 - 2.7e-27 94.5 7.3 5.8e-13 48.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PIP5K PF01504.18 CEG39287.1 - 1.9e-69 234.0 0.2 9.2e-69 231.7 0.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG39287.1 - 0.0036 16.6 3.4 0.0036 16.6 3.4 1.8 2 1 1 3 3 3 1 7 transmembrane receptor (Secretin family) DoxX_2 PF13564.6 CEG39287.1 - 0.0095 16.0 0.1 0.036 14.2 0.0 1.9 2 0 0 2 2 2 1 DoxX-like family DUF3112 PF11309.8 CEG39287.1 - 3.2 7.1 7.1 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Clat_adaptor_s PF01217.20 CEG39288.1 - 4.4e-18 65.6 0.4 5.3e-18 65.3 0.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FHA PF00498.26 CEG39289.1 - 2.9e-13 50.0 0.6 6.7e-13 48.8 0.6 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG39289.1 - 0.00019 21.7 0.2 0.001 19.4 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF2894 PF11445.8 CEG39289.1 - 0.0071 16.8 0.8 0.0071 16.8 0.8 3.4 2 2 1 3 3 3 1 Protein of unknown function (DUF2894) Biotin_lipoyl PF00364.22 CEG39290.1 - 5.5e-15 55.0 0.5 9.2e-15 54.2 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme EF-hand_7 PF13499.6 CEG39291.1 - 8.8e-12 45.3 0.2 5e-08 33.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG39291.1 - 3.5e-09 35.5 1.1 0.0044 16.5 0.2 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CEG39291.1 - 1.1e-07 31.2 1.0 0.1 12.6 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CEG39291.1 - 0.00014 21.2 0.8 0.011 15.2 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CEG39291.1 - 0.0004 20.7 0.0 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CEG39291.1 - 0.0024 17.7 1.6 1.7 8.6 0.1 2.9 1 1 2 3 3 3 3 EF-hand domain pair Prolamin_like PF05617.11 CEG39292.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolamin-like Arm PF00514.23 CEG39292.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Ricin_B_lectin PF00652.22 CEG39293.1 - 5e-14 52.6 6.0 1.2e-13 51.4 6.0 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 CEG39293.1 - 0.023 14.3 0.3 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 CybS PF05328.12 CEG39294.1 - 2.5e-13 49.8 0.1 3.2e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit tRNA_bind PF01588.20 CEG39295.1 - 1.7e-27 95.3 0.0 3.3e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain Cnd1 PF12717.7 CEG39296.1 - 3.3e-19 69.5 7.5 7.4e-17 61.9 0.3 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CEG39296.1 - 0.0001 21.6 6.1 0.00024 20.4 0.6 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CEG39296.1 - 0.00096 19.2 7.5 1.7 9.1 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 CEG39296.1 - 0.0068 16.8 2.8 3.7 8.0 0.1 4.0 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CEG39296.1 - 0.14 12.7 0.3 12 6.5 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat RTP1_C1 PF10363.9 CEG39296.1 - 0.23 11.6 3.5 1.3 9.2 0.0 4.2 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 MvaI_BcnI PF15515.6 CEG39296.1 - 0.41 10.4 3.2 1 9.2 3.2 1.7 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Cohesin_HEAT PF12765.7 CEG39296.1 - 3.4 8.0 5.1 68 3.9 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion bZIP_1 PF00170.21 CEG39297.1 - 1.4e-06 28.3 27.2 0.0045 17.0 11.5 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 CEG39297.1 - 3.3e-05 23.9 39.6 0.0049 16.9 19.8 2.4 2 0 0 2 2 2 2 Basic region leucine zipper MPS2 PF17060.5 CEG39297.1 - 0.011 15.1 1.3 0.011 15.1 1.3 1.6 2 0 0 2 2 2 0 Monopolar spindle protein 2 bZIP_Maf PF03131.17 CEG39297.1 - 0.013 16.0 22.1 0.59 10.7 8.8 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor zinc_ribbon_16 PF17034.5 CEG39299.1 - 1.9e-15 57.2 19.8 1.7e-10 41.2 9.5 2.9 1 1 1 2 2 2 2 Zinc-ribbon like family Acyl-CoA_dh_C PF12806.7 CEG39299.1 - 0.17 12.0 0.2 0.39 10.9 0.2 1.5 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Ricin_B_lectin PF00652.22 CEG39300.1 - 4.6e-12 46.3 6.4 1.7e-11 44.4 6.3 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain BRX_assoc PF16627.5 CEG39300.1 - 0.0075 16.4 0.4 0.034 14.3 0.2 2.1 2 0 0 2 2 2 1 Unstructured region between BRX_N and BRX domain RicinB_lectin_2 PF14200.6 CEG39300.1 - 0.031 15.0 5.6 0.37 11.5 0.3 2.9 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like TPR_19 PF14559.6 CEG39301.1 - 8.9e-11 42.1 8.0 3.6e-05 24.2 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG39301.1 - 9.1e-08 32.2 7.1 0.005 17.0 0.2 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CEG39301.1 - 6.6e-07 29.6 1.1 0.76 10.2 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39301.1 - 9e-07 29.4 1.8 0.0001 22.9 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG39301.1 - 2.7e-06 26.8 4.2 1e-05 24.9 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39301.1 - 1.7e-05 25.2 3.3 1.3 10.0 0.5 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39301.1 - 5.6e-05 22.9 6.1 0.14 12.3 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39301.1 - 0.00018 21.2 3.8 0.76 9.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39301.1 - 0.0023 17.8 1.4 8.7 6.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39301.1 - 0.0058 16.9 7.7 1 9.7 0.7 5.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39301.1 - 0.0091 16.1 3.1 5.2 7.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39301.1 - 0.014 15.1 1.3 0.14 11.9 0.1 3.2 2 1 1 3 3 3 0 TPR repeat Sec16_C PF12931.7 CEG39301.1 - 0.059 13.0 1.4 0.095 12.3 0.2 1.9 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 TPR_17 PF13431.6 CEG39301.1 - 0.1 13.0 0.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39301.1 - 0.19 12.5 4.6 1.8e+02 3.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1736 PF08409.11 CEG39302.1 - 2.6e-16 59.4 2.8 5.4e-16 58.4 1.9 2.0 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 CEG39302.1 - 2.7e-12 45.9 0.9 0.00013 21.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39302.1 - 1.7e-11 43.3 1.5 0.00047 20.1 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39302.1 - 7.7e-10 38.2 2.7 0.0032 17.5 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39302.1 - 2e-08 34.4 0.6 0.013 15.7 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 CEG39302.1 - 4.9e-06 25.7 0.1 0.0015 17.5 0.0 2.4 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CEG39302.1 - 6.6e-06 25.8 0.2 0.014 15.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39302.1 - 1.8e-05 25.1 0.2 8.5e-05 23.0 0.3 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39302.1 - 2.6e-05 23.9 0.2 1 9.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39302.1 - 2.9e-05 24.5 0.1 0.016 16.0 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39302.1 - 6.2e-05 23.4 0.4 0.018 15.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39302.1 - 7e-05 22.9 0.2 0.31 11.5 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39302.1 - 0.00063 20.3 0.0 0.28 11.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG39302.1 - 0.0091 16.1 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG39302.1 - 0.012 14.9 0.2 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39302.1 - 0.024 14.3 1.5 4.7 7.0 0.0 3.7 3 2 2 5 5 5 0 TPR repeat Wzy_C_2 PF11846.8 CEG39302.1 - 0.039 13.9 0.3 0.45 10.4 0.0 2.7 3 0 0 3 3 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_5 PF12688.7 CEG39302.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF547 PF04784.14 CEG39304.1 - 1.1e-11 44.8 0.0 3.9e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF547 UCR_14kD PF02271.16 CEG39305.1 - 1.2e-21 76.5 0.1 1.4e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1959 PF09218.10 CEG39305.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1959) DUF494 PF04361.13 CEG39305.1 - 0.077 12.9 0.1 0.098 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DUF3128 PF11326.8 CEG39307.1 - 1.2e-17 64.0 1.4 1.5e-17 63.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCC-bdg_PDZ PF10506.9 CEG39308.1 - 0.12 12.4 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FAM92 PF06730.11 CEG39308.1 - 0.2 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein JmjC PF02373.22 CEG39309.1 - 6e-42 142.7 0.0 1.3e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 CEG39309.1 - 8e-12 45.4 8.2 1.7e-11 44.3 8.2 1.5 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.17 CEG39309.1 - 4.6e-08 32.9 0.6 1.5e-07 31.2 0.6 1.9 1 1 0 1 1 1 1 jmjN domain DUF2181 PF10223.9 CEG39310.1 - 6e-45 153.6 0.0 8.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) AA_permease_2 PF13520.6 CEG39311.1 - 1.4e-31 109.7 49.8 2e-31 109.3 49.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG39311.1 - 2.7e-19 69.1 45.3 3.7e-19 68.7 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG39312.1 - 1.2e-20 73.6 40.2 4.7e-12 45.2 24.2 3.1 2 1 1 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 CEG39312.1 - 1.7e-15 56.8 47.7 1.3e-13 50.6 27.0 3.0 1 1 1 2 2 2 2 Amino acid permease UPF0542 PF15086.6 CEG39312.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DUF3188 PF11384.8 CEG39312.1 - 8.1 6.2 11.7 0.49 10.1 1.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Nipped-B_C PF12830.7 CEG39316.1 - 0.019 14.9 1.2 0.096 12.6 0.2 2.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Myb_DNA-binding PF00249.31 CEG39317.1 - 1.7e-30 104.9 6.9 3.1e-15 56.1 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG39317.1 - 1.3e-23 83.0 2.0 1e-14 54.5 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG39317.1 - 2.2e-06 27.5 1.0 0.0054 16.6 0.1 2.4 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEG39317.1 - 0.0023 18.1 2.2 0.27 11.5 0.3 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CEG39317.1 - 0.0076 16.3 0.1 0.035 14.1 0.1 2.0 1 1 1 2 2 2 1 SLIDE MADF_DNA_bdg PF10545.9 CEG39317.1 - 0.013 15.8 6.6 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LGFP PF08310.11 CEG39317.1 - 0.065 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 LGFP repeat Mannosyl_trans3 PF11051.8 CEG39318.1 - 3.7e-29 101.9 0.0 5.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative SSXT PF05030.12 CEG39327.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) DUF5033 PF16436.5 CEG39328.1 - 0.059 13.3 1.0 0.08 12.9 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) DUF3261 PF11659.8 CEG39328.1 - 2 8.2 6.2 10 6.0 6.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) JAB PF01398.21 CEG39330.1 - 2.8e-15 56.3 0.0 6.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEG39330.1 - 7.6e-06 25.7 0.3 5.9e-05 22.8 0.0 2.4 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain Lip_prot_lig_C PF10437.9 CEG39330.1 - 0.18 11.8 0.0 0.65 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus CIAPIN1 PF05093.13 CEG39331.1 - 8.3e-18 64.8 16.9 2.2e-12 47.4 5.3 2.4 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis KH_1 PF00013.29 CEG39332.1 - 4.1e-09 36.1 0.0 9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 KH domain DNA_pol_B_exo2 PF10108.9 CEG39332.1 - 0.032 13.9 0.2 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB LuxT_C PF18285.1 CEG39332.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain S19 PF06756.11 CEG39333.1 - 0.12 12.3 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Chorion protein S19 C-terminal TPR_2 PF07719.17 CEG39334.1 - 1.2e-07 31.2 1.8 0.0068 16.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39334.1 - 1.4e-07 31.0 1.0 0.0081 15.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39334.1 - 3.6e-06 27.2 1.0 0.043 14.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39334.1 - 0.0015 18.6 3.3 0.093 13.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39334.1 - 0.0021 17.9 2.3 0.32 11.1 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39334.1 - 0.11 13.3 0.1 8.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 CEG39338.1 - 1.5e-09 38.3 10.8 0.0022 18.8 0.0 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat bZIP_1 PF00170.21 CEG39339.1 - 2.3e-07 30.8 6.8 8.3e-07 29.0 6.8 2.0 1 0 0 1 1 1 1 bZIP transcription factor AAA_23 PF13476.6 CEG39339.1 - 0.13 12.8 13.8 0.039 14.5 2.3 3.4 4 0 0 4 4 4 0 AAA domain PX PF00787.24 CEG39340.1 - 0.0016 18.4 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 PX domain DUF4261 PF14080.6 CEG39340.1 - 0.18 12.0 0.1 7.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) LMBR1 PF04791.16 CEG39340.1 - 2.5 6.9 4.1 3 6.7 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Frag1 PF10277.9 CEG39341.1 - 7e-16 58.4 6.5 9.5e-16 58.0 6.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 CEG39341.1 - 0.051 13.2 0.2 0.051 13.2 0.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF998) Ni_hydr_CYTB PF01292.20 CEG39341.1 - 0.08 12.5 0.5 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4167 PF13763.6 CEG39341.1 - 0.23 11.6 0.0 0.41 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) DUF1772 PF08592.11 CEG39341.1 - 0.77 10.1 8.8 5.9 7.2 8.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) LuxE PF04443.12 CEG39342.1 - 0.12 11.4 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE gag_pre-integrs PF13976.6 CEG39343.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain ThiJ_like PF17124.5 CEG39344.1 - 0.051 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 ThiJ/PfpI family-like kleA_kleC PF17383.2 CEG39346.1 - 0.061 13.7 0.4 0.061 13.7 0.4 6.1 6 0 0 6 6 6 0 Uncharacterized KorC regulated protein A T2SSF PF00482.23 CEG39346.1 - 0.78 9.7 3.8 11 6.0 3.8 3.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DLH PF01738.18 CEG39348.1 - 7.9e-08 32.1 0.1 1.5e-06 28.0 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CEG39348.1 - 3.1e-05 23.4 0.2 9.1e-05 21.8 0.2 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 CEG39348.1 - 0.00097 19.1 0.5 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4050 PF13259.6 CEG39348.1 - 0.0084 16.5 0.3 0.042 14.2 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4050) Abhydrolase_1 PF00561.20 CEG39348.1 - 0.024 14.3 0.1 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3530 PF12048.8 CEG39348.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 CEG39348.1 - 0.049 13.5 0.1 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CEG39348.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_31 PF13614.6 CEG39348.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.16 CEG39349.1 - 3.6e-29 101.8 6.1 3.6e-29 101.8 6.1 2.0 2 1 1 3 3 3 1 Translocation protein Sec62 MgtE PF01769.16 CEG39349.1 - 0.97 9.8 8.9 0.49 10.8 6.8 1.5 2 0 0 2 2 2 0 Divalent cation transporter Cadherin_C_2 PF16492.5 CEG39349.1 - 1.6 9.6 4.0 5 7.9 4.0 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Pur_ac_phosph_N PF16656.5 CEG39350.1 - 1.2e-17 64.2 0.0 3e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 CEG39350.1 - 2.3e-14 54.4 4.7 5.4e-14 53.2 4.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG39350.1 - 1.9e-11 44.6 0.3 7.4e-11 42.8 0.1 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C FliO PF04347.13 CEG39353.1 - 0.023 15.0 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Bromodomain PF00439.25 CEG39355.1 - 9.1e-35 118.6 0.1 3.6e-14 52.6 0.0 3.3 3 0 0 3 3 3 3 Bromodomain SR-25 PF10500.9 CEG39355.1 - 0.068 12.8 35.0 0.12 11.9 35.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 CEG39355.1 - 0.21 10.1 19.0 0.27 9.8 19.0 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CEG39355.1 - 0.56 8.9 15.8 0.81 8.4 15.8 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CEG39355.1 - 0.63 9.2 13.5 1 8.5 13.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.13 CEG39355.1 - 0.76 9.3 17.9 1.1 8.8 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.7 CEG39355.1 - 1.8 6.6 12.8 2.4 6.2 12.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CEG39355.1 - 3.2 6.5 19.4 4.3 6.1 19.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 CEG39355.1 - 4.2 6.3 14.7 6.4 5.7 14.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 CEG39355.1 - 7.8 6.5 9.7 12 5.9 9.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bromodomain PF00439.25 CEG39356.1 - 3.3e-22 78.3 0.2 2.6e-14 53.0 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Cyclin_N PF00134.23 CEG39357.1 - 4.4e-12 45.8 0.1 8.8e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEG39357.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HGTP_anticodon PF03129.20 CEG39359.1 - 8.5e-21 73.9 0.0 1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain Radical_SAM PF04055.21 CEG39359.1 - 0.0017 18.7 0.0 0.0024 18.3 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily BORCS7 PF16088.5 CEG39359.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DAHP_synth_1 PF00793.20 CEG39360.1 - 1.2e-95 319.5 0.0 1.5e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PGM_PMM_II PF02879.16 CEG39360.1 - 0.12 13.0 0.0 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Chorismate_synt PF01264.21 CEG39361.1 - 9e-140 465.0 0.0 1.3e-139 464.4 0.0 1.2 1 1 0 1 1 1 1 Chorismate synthase SAC3_GANP PF03399.16 CEG39362.1 - 1.1e-20 74.2 0.1 6.5e-19 68.4 0.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family Glutaredoxin PF00462.24 CEG39363.1 - 1.2e-20 73.4 0.0 2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CEG39363.1 - 0.024 15.0 0.0 0.076 13.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF656 PF04920.12 CEG39363.1 - 0.08 12.9 0.1 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF656) PP2C PF00481.21 CEG39365.1 - 1.4e-59 201.8 0.0 1.7e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG39365.1 - 2e-06 27.6 0.0 1.5e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C S-AdoMet_synt_N PF00438.20 CEG39365.1 - 0.12 13.1 0.3 22 5.8 0.0 3.2 2 1 1 3 3 3 0 S-adenosylmethionine synthetase, N-terminal domain MAT1-1-2 PF17043.5 CEG39366.1 - 0.15 11.9 1.1 0.22 11.4 0.2 1.7 2 0 0 2 2 2 0 Mating type protein 1-1-2 of unknown function DEAD PF00270.29 CEG39368.1 - 1.7e-44 151.7 0.1 2.7e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG39368.1 - 4.4e-32 110.7 0.1 1.3e-30 106.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG39368.1 - 1e-06 28.9 0.0 2.8e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEG39368.1 - 0.0013 19.1 0.1 0.0039 17.5 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG39368.1 - 0.0035 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG39368.1 - 0.0076 16.5 0.3 0.026 14.8 0.3 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEG39368.1 - 0.054 12.7 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CEG39368.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase DNA_III_psi PF03603.13 CEG39368.1 - 0.16 12.2 0.2 16 5.8 0.0 2.8 2 1 1 3 3 3 0 DNA polymerase III psi subunit Pkinase PF00069.25 CEG39370.1 - 3.8e-58 196.9 0.0 5.3e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39370.1 - 9.5e-32 110.3 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG39370.1 - 0.00026 20.4 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 CEG39370.1 - 0.0014 18.7 13.7 0.0015 18.6 10.7 2.2 2 0 0 2 2 2 1 FYVE zinc finger Kdo PF06293.14 CEG39370.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG39370.1 - 0.0094 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEG39370.1 - 0.024 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FYVE_2 PF02318.16 CEG39370.1 - 7.1 6.9 10.6 9.8 6.4 9.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger E1-E2_ATPase PF00122.20 CEG39371.1 - 1.2e-22 80.4 0.1 4.8e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEG39371.1 - 8.2e-15 55.7 0.3 1.9e-07 31.6 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG39371.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEG39371.1 - 0.0008 19.2 1.2 0.29 10.8 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Myosin_TH1 PF06017.13 CEG39372.1 - 0.0035 17.0 0.1 0.097 12.3 0.0 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding HA70_C PF17993.1 CEG39373.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain FdsD PF11390.8 CEG39373.1 - 0.23 11.8 1.1 34 4.9 0.2 2.7 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD TPR_12 PF13424.6 CEG39374.1 - 1.1e-38 131.4 10.0 1.5e-13 50.8 1.3 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG39374.1 - 1.1e-35 120.5 11.5 1.2e-08 34.5 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39374.1 - 6.4e-20 70.1 16.5 7.6e-05 22.4 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39374.1 - 3.3e-15 54.9 17.3 0.039 14.1 1.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39374.1 - 3.6e-15 54.8 17.2 0.00092 19.2 0.2 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39374.1 - 1.6e-12 46.5 13.0 0.025 14.6 0.1 7.1 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39374.1 - 9.7e-09 35.3 4.7 0.12 13.0 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF2225 PF09986.9 CEG39374.1 - 2.5e-07 30.7 2.9 0.0023 17.7 0.1 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.6 CEG39374.1 - 5.2e-07 30.0 6.7 2.3 9.3 0.1 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39374.1 - 7.9e-07 29.5 4.0 0.0023 18.4 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39374.1 - 1.3e-05 25.3 3.7 0.71 10.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39374.1 - 3.9e-05 23.3 11.3 0.2 11.3 0.2 5.8 7 0 0 7 7 7 2 TPR repeat SNAP PF14938.6 CEG39374.1 - 5e-05 22.9 6.4 0.0098 15.3 0.6 2.9 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 CEG39374.1 - 0.00049 20.7 6.3 3 8.6 0.2 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat RPN6_N PF18055.1 CEG39374.1 - 0.00067 20.0 3.0 0.032 14.6 0.5 3.0 1 1 3 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain ANAPC5 PF12862.7 CEG39374.1 - 0.0014 18.7 4.0 0.012 15.7 0.1 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 CEG39374.1 - 0.0019 17.7 2.8 5 6.4 0.1 3.0 1 1 0 2 2 2 1 MalT-like TPR region DUF2753 PF10952.8 CEG39374.1 - 0.02 15.0 0.5 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) Vps54_N PF10475.9 CEG39374.1 - 0.034 13.4 0.1 1.4 8.1 0.0 2.7 1 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF4404 PF14357.6 CEG39374.1 - 0.035 14.8 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) IclR PF01614.18 CEG39374.1 - 0.046 13.5 0.2 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional regulator MIT PF04212.18 CEG39374.1 - 0.13 12.3 14.1 1.2 9.2 2.6 4.2 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CEG39374.1 - 5.1 7.2 9.3 12 6.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat GerPC PF10737.9 CEG39377.1 - 0.074 13.1 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC QSregVF PF13652.6 CEG39377.1 - 0.2 11.7 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Abhydrolase_6 PF12697.7 CEG39378.1 - 2.1e-09 38.3 0.0 3.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEG39378.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CEG39378.1 - 2.5e-05 24.5 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF1057 PF06342.12 CEG39378.1 - 0.0007 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_C23 PF05379.11 CEG39378.1 - 0.024 14.8 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Carlavirus endopeptidase DUF4191 PF13829.6 CEG39378.1 - 0.14 11.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) LIDHydrolase PF10230.9 CEG39379.1 - 1.8e-52 178.5 0.7 2.4e-52 178.1 0.7 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CEG39379.1 - 1.2e-05 25.1 0.0 0.0001 22.0 0.0 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG39379.1 - 1.3e-05 24.6 0.2 2.6e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 CEG39379.1 - 7.9e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 CEG39379.1 - 0.00019 22.1 0.0 0.0003 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CEG39379.1 - 0.036 13.9 0.2 0.57 10.0 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase Thioesterase PF00975.20 CEG39379.1 - 0.039 14.0 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain BAAT_C PF08840.11 CEG39379.1 - 0.061 13.2 0.2 0.89 9.4 0.0 2.5 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF547 PF04784.14 CEG39380.1 - 0.014 15.4 0.4 0.056 13.5 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF547 NdhM PF10664.9 CEG39380.1 - 0.089 13.1 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M 3HCDH_N PF02737.18 CEG39381.1 - 1.5e-58 197.7 0.1 2.1e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CEG39381.1 - 7.7e-30 103.4 0.0 5.6e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEG39381.1 - 0.00012 22.3 1.2 0.00027 21.1 1.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 CEG39381.1 - 0.0011 18.5 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CEG39381.1 - 0.0018 17.7 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CEG39381.1 - 0.032 14.8 0.1 0.059 14.0 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CbiA PF01656.23 CEG39381.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2127 PF09900.9 CEG39381.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) Gly-zipper_Omp PF13488.6 CEG39382.1 - 4.5e-09 36.2 88.9 0.2 11.7 21.2 4.3 1 1 2 3 3 3 2 Glycine zipper Gly-zipper_YMGG PF13441.6 CEG39382.1 - 1.7e-08 34.1 81.7 0.79 9.5 21.7 4.2 1 1 1 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 CEG39382.1 - 9.8e-06 25.3 78.3 8.5 6.2 18.5 4.6 2 1 1 3 3 3 1 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 CEG39382.1 - 1.1e-05 25.2 88.3 0.36 10.7 21.9 4.5 1 1 2 3 3 3 1 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 CEG39382.1 - 0.0047 17.0 79.3 6 7.1 21.2 4.6 2 1 1 3 3 3 2 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 CEG39382.1 - 0.89 9.8 55.1 9.8e+02 -0.0 9.5 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF456) Transgly_assoc PF04226.13 CEG39382.1 - 1.7 8.9 59.8 0.69 10.2 17.6 4.7 1 1 3 4 4 4 0 Transglycosylase associated protein DUF1269 PF06897.12 CEG39382.1 - 6.4 7.1 51.8 4.6e+02 1.2 1.9 4.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1269) Pkinase PF00069.25 CEG39383.1 - 6.1e-54 183.1 0.0 7.7e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39383.1 - 4e-48 163.9 0.0 4.9e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG39383.1 - 0.01 14.8 0.0 0.04 12.9 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CEG39383.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG39383.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mo25 PF08569.11 CEG39384.1 - 1.5e-119 399.2 1.7 1.7e-119 399.0 1.7 1.0 1 0 0 1 1 1 1 Mo25-like Copine PF07002.16 CEG39385.1 - 6.2e-57 192.5 0.0 9.7e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Copine zf-C3HC4_3 PF13920.6 CEG39385.1 - 2.6e-08 33.6 10.2 4.2e-08 32.9 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) vWA-TerF-like PF10138.9 CEG39385.1 - 0.00062 19.9 0.1 0.0025 18.0 0.1 1.9 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-C3HC4_2 PF13923.6 CEG39385.1 - 0.0016 18.2 11.1 0.0037 17.1 11.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG39385.1 - 0.0089 15.9 8.7 0.026 14.4 8.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG39385.1 - 0.72 9.8 14.8 5.6 6.9 12.2 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEG39385.1 - 1.4 9.0 9.5 3.4 7.8 9.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CEG39385.1 - 3.2 7.8 13.4 39 4.3 14.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Ammonium_transp PF00909.21 CEG39387.1 - 8.9e-64 215.6 23.5 1.1e-63 215.3 23.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Glucan_synthase PF02364.15 CEG39388.1 - 3.8e-184 614.2 23.2 1.3e-166 556.2 8.2 2.9 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEG39388.1 - 5.3e-23 81.8 4.1 4.2e-22 78.8 4.1 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 CEG39388.1 - 1.5e-18 66.9 30.4 1.5e-18 66.9 30.4 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG39388.1 - 2.2e-14 53.2 25.2 2.2e-14 53.2 25.2 5.4 4 2 3 7 7 7 1 Major Facilitator Superfamily RabGAP-TBC PF00566.18 CEG39392.1 - 5.7e-41 140.5 0.1 8.8e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Amidohydro_1 PF01979.20 CEG39393.1 - 1.1e-69 235.4 1.0 1.3e-69 235.1 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEG39393.1 - 1e-16 61.5 2.6 3.8e-14 53.0 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family DUF1771 PF08590.10 CEG39394.1 - 3.8e-20 72.0 4.4 7.2e-20 71.1 4.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEG39394.1 - 3.5e-09 36.9 0.6 1.9e-08 34.5 0.4 2.4 4 0 0 4 4 4 1 Smr domain zf_CCCH_4 PF18345.1 CEG39394.1 - 1e-07 31.7 7.6 4.1e-05 23.5 1.3 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 CEG39394.1 - 0.0011 19.3 6.8 0.23 12.0 1.0 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CEG39394.1 - 0.16 12.2 6.3 2.1 8.6 6.3 2.3 1 1 0 1 1 1 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CEG39394.1 - 0.25 11.2 12.7 1.9 8.4 3.4 3.2 2 2 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CEG39394.1 - 1.8 9.3 10.3 0.69 10.6 1.6 2.8 2 1 1 3 3 3 0 Torus domain Proteasome PF00227.26 CEG39395.1 - 7.6e-46 156.0 0.1 9.2e-46 155.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Piwi PF02171.17 CEG39397.1 - 4.8e-90 301.9 0.0 6.9e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 CEG39397.1 - 2e-15 56.2 0.0 5.8e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 CEG39397.1 - 2.8e-15 56.3 0.0 5.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CEG39397.1 - 3.7e-15 56.8 0.0 1.3e-14 55.0 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 CEG39397.1 - 7.2e-11 42.3 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CEG39397.1 - 3.5e-10 40.0 0.1 1.4e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute FTCD PF02971.14 CEG39399.1 - 0.068 13.2 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase domain RPA PF10134.9 CEG39399.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Replication initiator protein A Glyco_hydro_12 PF01670.16 CEG39402.1 - 2.7e-18 66.8 0.3 3.5e-18 66.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 HTH_52 PF18576.1 CEG39402.1 - 0.13 12.5 0.2 0.31 11.3 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 CEG39403.1 - 1.5e-27 96.6 0.0 2.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39403.1 - 1.2e-26 93.6 0.0 2.7e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG39403.1 - 0.0081 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG39403.1 - 0.061 12.7 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.21 CEG39405.1 - 1.9e-11 43.9 19.3 5e-11 42.6 19.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 CEG39405.1 - 0.037 14.4 0.1 0.096 13.0 0.1 1.7 1 0 0 1 1 1 0 GAF domain DpnI PF06044.12 CEG39405.1 - 0.98 9.0 5.9 1.8 8.2 5.9 1.3 1 0 0 1 1 1 0 Dam-replacing family Arf PF00025.21 CEG39408.1 - 2.7e-20 72.5 0.7 2.7e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CEG39408.1 - 0.00061 19.3 0.2 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CEG39408.1 - 0.0012 19.1 0.4 0.27 11.4 0.1 2.5 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CEG39408.1 - 0.0058 16.4 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CEG39408.1 - 0.02 15.2 0.0 0.051 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEG39408.1 - 0.028 15.0 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CEG39408.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG39408.1 - 0.058 13.3 0.2 0.082 12.8 0.2 1.4 1 1 0 1 1 1 0 NACHT domain cobW PF02492.19 CEG39408.1 - 0.06 12.9 0.2 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CEG39408.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CEG39408.1 - 0.095 12.3 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Ras family ATPase_2 PF01637.18 CEG39408.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 CEG39408.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 CEG39408.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Aa_trans PF01490.18 CEG39409.1 - 1.3e-31 109.8 23.7 1.8e-31 109.3 23.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG16 PF08614.11 CEG39410.1 - 0.0058 16.9 2.2 0.0071 16.6 2.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IF-2B PF01008.17 CEG39411.1 - 5.7e-77 258.7 0.1 6.7e-77 258.5 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Oscp1 PF10188.9 CEG39414.1 - 8.7e-55 185.5 6.5 3e-43 147.9 2.4 2.1 1 1 1 2 2 2 2 Organic solute transport protein 1 Orthopox_A43R PF06517.11 CEG39414.1 - 0.012 15.4 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A43R protein DUF5088 PF17008.5 CEG39414.1 - 0.077 12.7 0.1 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) DUF5461 PF17545.2 CEG39414.1 - 0.17 12.2 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5461) VRR_NUC PF08774.11 CEG39415.1 - 2.1e-11 43.8 0.0 6.5e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 VRR-NUC domain DDE_1 PF03184.19 CEG39416.1 - 1.4e-16 60.7 0.6 2e-16 60.1 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Bestrophin PF01062.21 CEG39418.1 - 2.8e-20 72.9 2.6 3.3e-19 69.4 2.6 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PI3_PI4_kinase PF00454.27 CEG39419.1 - 4.1e-44 151.3 0.0 6e-43 147.5 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEG39419.1 - 1.4e-42 145.2 0.8 2.6e-42 144.3 0.8 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 CEG39419.1 - 6.4e-31 107.0 2.2 1.4e-15 57.7 0.4 3.2 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 CEG39419.1 - 5.5e-10 39.6 1.5 0.00019 21.8 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CEG39419.1 - 2.3e-05 24.6 5.7 0.094 13.0 1.6 4.2 3 1 0 3 3 3 2 Pleckstrin homology domain PI3K_rbd PF00794.18 CEG39419.1 - 3.2e-05 24.1 0.1 7.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 CEG39419.1 - 9e-05 22.4 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CEG39419.1 - 0.0059 16.0 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) CRM1_C PF08767.11 CEG39419.1 - 0.075 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 CRM1 C terminal DUF2833 PF11090.8 CEG39419.1 - 0.13 12.6 0.1 0.82 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) PH_4 PF15404.6 CEG39419.1 - 0.21 11.4 0.7 1 9.1 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain BCIP PF13862.6 CEG39421.1 - 2.5e-46 158.1 0.3 3.8e-46 157.5 0.3 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein BssC_TutF PF08201.11 CEG39423.1 - 0.16 12.0 2.1 0.44 10.6 2.1 1.8 1 1 0 1 1 1 0 BssC/TutF protein DDE_1 PF03184.19 CEG39424.1 - 3.4e-06 26.8 0.0 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_Tyr PF07714.17 CEG39425.1 - 2.9e-44 151.3 0.1 6.6e-43 146.8 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CEG39425.1 - 6.1e-39 134.0 0.0 1.4e-38 132.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Haspin_kinase PF12330.8 CEG39425.1 - 0.063 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Alk_phosphatase PF00245.20 CEG39428.1 - 6.9e-09 35.1 0.0 8.8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase cobW PF02492.19 CEG39429.1 - 1.2e-07 31.5 0.1 2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEG39429.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 CEG39429.1 - 0.11 12.0 0.2 0.16 11.5 0.2 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HTH_Tnp_Tc3_2 PF01498.18 CEG39431.1 - 0.0083 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Transposase Chromo PF00385.24 CEG39433.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2112 PF09885.9 CEG39437.1 - 0.047 13.7 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Vta1 PF04652.16 CEG39439.1 - 4.8e-43 146.6 0.9 6.7e-43 146.1 0.2 1.6 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CEG39439.1 - 8e-05 22.3 0.4 0.00017 21.2 0.4 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain ECM11 PF15463.6 CEG39439.1 - 0.098 13.2 0.3 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Extracellular mutant protein 11 tRNA_m1G_MT PF01746.21 CEG39440.1 - 3.9e-29 101.8 0.1 7.7e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase G6PD_bact PF10786.9 CEG39440.1 - 0.031 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) RICTOR_V PF14668.6 CEG39441.1 - 0.052 13.8 0.0 0.066 13.5 0.0 1.3 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Metallophos PF00149.28 CEG39442.1 - 5e-39 134.9 0.1 6.5e-39 134.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEG39442.1 - 0.00011 22.6 2.2 0.00022 21.6 0.3 2.2 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CEG39442.1 - 0.073 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain T3SS_needle_E PF08988.10 CEG39446.1 - 0.02 15.1 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Torus PF16131.5 CEG39452.1 - 1.3e-12 48.3 2.4 5.2e-05 23.9 0.1 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CEG39452.1 - 2.6e-10 40.0 13.4 4.5e-06 26.4 1.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG39452.1 - 5.2e-09 35.9 17.9 0.00025 21.0 5.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEG39452.1 - 6.9e-08 32.1 20.8 1.5e-05 24.7 3.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger RWD PF05773.22 CEG39452.1 - 4.1e-05 23.8 0.0 0.00014 22.1 0.0 1.9 1 0 0 1 1 1 1 RWD domain Myb_DNA-binding PF00249.31 CEG39452.1 - 0.00021 21.4 0.2 0.00051 20.2 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCCH_3 PF15663.5 CEG39452.1 - 0.0036 17.5 6.9 0.055 13.7 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger containing family Myb_DNA-bind_6 PF13921.6 CEG39452.1 - 0.051 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain UQ_con PF00179.26 CEG39452.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme zf-CCCH_2 PF14608.6 CEG39452.1 - 0.3 11.6 19.8 0.21 12.1 3.7 3.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CW PF07496.15 CEG39453.1 - 0.0015 18.5 0.1 0.0038 17.2 0.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger Mitoc_L55 PF09776.9 CEG39453.1 - 0.1 12.4 0.3 0.42 10.4 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 EMP70 PF02990.16 CEG39454.1 - 1.4e-213 710.3 11.1 1.4e-213 710.3 11.1 1.4 1 1 1 2 2 2 1 Endomembrane protein 70 RELT PF12606.8 CEG39454.1 - 2.4 7.2 9.1 0.43 9.6 2.6 3.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 adh_short PF00106.25 CEG39456.1 - 8.3e-16 58.0 0.3 5.7e-15 55.3 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG39456.1 - 8.1e-12 45.2 0.2 2.8e-11 43.4 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CEG39456.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CEG39456.1 - 0.072 12.5 0.0 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Thiolase_C PF02803.18 CEG39456.1 - 0.12 12.0 0.4 0.44 10.2 0.1 2.1 1 1 1 2 2 2 0 Thiolase, C-terminal domain KR PF08659.10 CEG39456.1 - 0.15 12.0 1.8 3.4 7.5 0.5 2.3 1 1 1 2 2 2 0 KR domain Mucin15 PF15672.5 CEG39456.1 - 0.18 11.3 0.8 0.29 10.6 0.2 1.6 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 NAD_binding_6 PF08030.12 CEG39457.1 - 1.2e-32 113.2 0.1 5.9e-32 110.9 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG39457.1 - 2.1e-22 79.3 0.0 5e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CEG39457.1 - 3.6e-14 53.0 4.9 3.6e-14 53.0 4.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 CEG39457.1 - 0.0042 17.5 0.1 0.014 15.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG39457.1 - 0.073 13.0 0.0 2.1 8.5 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CEG39457.1 - 0.08 12.5 0.1 1.5 8.6 0.0 3.1 4 0 0 4 4 4 0 EF hand NAD_binding_1 PF00175.21 CEG39457.1 - 0.096 13.3 0.1 0.31 11.7 0.1 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Glu_cyclase_2 PF05096.12 CEG39459.1 - 2e-51 174.9 0.1 2.3e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase Arylsulfotrans PF05935.11 CEG39459.1 - 0.032 13.1 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) gag_pre-integrs PF13976.6 CEG39463.1 - 3.9e-07 29.8 0.0 7.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 CEG39463.1 - 2.8e-05 24.3 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 CEG39465.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 HTH-like domain SMC_Nse1 PF07574.13 CEG39468.1 - 1.6e-20 73.9 0.4 7.6e-16 58.6 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CEG39468.1 - 2.9e-06 27.5 11.3 5.3e-06 26.6 11.3 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 CEG39468.1 - 2.1e-05 24.8 10.7 3.8e-05 23.9 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 CEG39468.1 - 0.02 15.2 4.0 0.02 15.2 4.0 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG39468.1 - 0.025 14.7 6.3 0.091 12.9 6.3 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_4 PF14447.6 CEG39468.1 - 0.026 14.4 9.6 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3H1 PF10650.9 CEG39468.1 - 0.048 13.4 0.5 0.048 13.4 0.5 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain FeoA PF04023.14 CEG39468.1 - 0.08 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 FeoA domain zf-ribbon_3 PF13248.6 CEG39468.1 - 0.12 11.8 3.9 4.5 6.8 0.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain FANCL_C PF11793.8 CEG39468.1 - 1.5 9.0 10.9 36 4.6 10.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Zn-C2H2_12 PF18112.1 CEG39468.1 - 3 8.4 7.5 8 7.0 1.0 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zn_ribbon_17 PF17120.5 CEG39468.1 - 6.4 6.5 12.2 16 5.2 10.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type DUF498 PF04430.14 CEG39469.1 - 1.5e-28 99.0 0.0 2.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pkinase PF00069.25 CEG39471.1 - 1.3e-62 211.6 0.0 5.3e-62 209.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39471.1 - 3.8e-27 95.2 0.0 2.7e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CEG39471.1 - 0.00051 19.5 0.4 0.002 17.5 0.1 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG39471.1 - 0.0007 19.0 0.0 0.46 9.8 0.0 2.9 2 1 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CEG39471.1 - 0.0039 16.0 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG39471.1 - 0.013 15.5 0.1 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3907 PF13047.6 CEG39474.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) Coatomer_WDAD PF04053.14 CEG39477.1 - 3.5e-148 494.4 0.1 8.3e-148 493.1 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CEG39477.1 - 9.2e-32 108.6 10.9 8.7e-07 29.6 0.1 8.6 9 1 1 10 10 10 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 CEG39477.1 - 0.026 14.6 0.0 7 6.7 0.0 3.7 2 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CEG39477.1 - 0.055 12.1 0.5 3 6.4 0.0 3.2 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Clat_adaptor_s PF01217.20 CEG39478.1 - 7.8e-52 175.0 0.9 8.6e-52 174.8 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NUFIP1 PF10453.9 CEG39479.1 - 5.1e-08 32.6 1.0 1.8e-07 30.9 1.0 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCHC_2 PF13696.6 CEG39479.1 - 7.7e-08 32.0 9.8 2.2e-07 30.5 9.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf_CCCH_4 PF18345.1 CEG39479.1 - 0.0009 19.2 11.9 0.17 12.0 1.0 3.1 2 1 0 2 2 2 2 Zinc finger domain zf-CCHC PF00098.23 CEG39479.1 - 0.0014 18.6 3.6 0.0014 18.6 3.6 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF4769 PF15992.5 CEG39479.1 - 0.0043 16.9 5.4 0.42 10.4 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4769) zf-CCCH PF00642.24 CEG39479.1 - 0.0062 16.4 6.6 0.025 14.5 1.4 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEG39479.1 - 0.0086 16.8 7.4 0.068 13.9 1.0 2.8 1 1 1 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 CEG39479.1 - 0.25 11.9 8.0 0.94 10.1 1.8 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CEG39479.1 - 0.26 11.1 13.3 0.56 10.1 4.5 3.1 2 1 0 2 2 2 0 CCCH-type zinc finger zf-C2H2 PF00096.26 CEG39479.1 - 3.2 8.4 10.4 0.37 11.3 0.3 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Myb_DNA-bind_4 PF13837.6 CEG39480.1 - 0.053 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TPR_1 PF00515.28 CEG39483.1 - 1.5e-17 62.6 3.4 4e-06 26.4 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39483.1 - 3.7e-17 61.0 1.4 6.4e-05 22.8 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat Prefoldin_2 PF01920.20 CEG39483.1 - 9.1e-14 51.3 11.9 2.2e-13 50.1 8.5 2.4 3 0 0 3 3 2 1 Prefoldin subunit TPR_8 PF13181.6 CEG39483.1 - 2.9e-10 39.5 4.4 0.0021 18.1 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39483.1 - 1.4e-08 34.5 3.4 0.00021 21.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39483.1 - 7.3e-08 32.0 5.2 6.6e-06 25.7 0.5 3.4 3 1 1 4 4 4 1 TPR repeat TPR_7 PF13176.6 CEG39483.1 - 6.5e-07 28.9 0.1 0.0043 17.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39483.1 - 1.8e-06 28.5 0.0 0.0051 17.4 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39483.1 - 2.5e-06 27.7 3.4 0.036 14.4 2.5 4.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG39483.1 - 1.3e-05 24.9 3.3 0.044 13.7 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39483.1 - 3.8e-05 24.2 0.0 2.5 9.1 0.1 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39483.1 - 0.00022 21.7 0.4 0.0022 18.5 0.2 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39483.1 - 0.00033 21.1 0.4 2 9.2 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG39483.1 - 0.0021 18.1 0.0 6.2 7.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DHR10 PF18595.1 CEG39483.1 - 0.024 14.7 12.0 1.7 8.7 0.4 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain MIT PF04212.18 CEG39483.1 - 0.026 14.6 1.5 1.7 8.7 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sec34 PF04136.15 CEG39483.1 - 0.04 13.8 7.2 0.22 11.4 0.1 3.1 3 0 0 3 3 3 0 Sec34-like family BTAD PF03704.17 CEG39483.1 - 0.051 14.0 0.2 0.23 11.9 0.2 2.0 1 1 1 2 2 2 0 Bacterial transcriptional activator domain FUSC PF04632.12 CEG39483.1 - 0.12 10.9 1.2 0.14 10.6 0.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 CEG39483.1 - 0.2 11.9 15.3 2.1 8.6 2.4 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 CEG39483.1 - 0.26 11.3 9.6 1.1 9.3 0.6 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 CEG39483.1 - 0.32 11.5 9.2 2.5 8.6 0.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 CEG39483.1 - 0.36 11.1 9.6 6 7.1 0.6 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding SKA2 PF16740.5 CEG39483.1 - 0.42 10.4 11.4 0.69 9.7 1.0 3.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 ANAPC3 PF12895.7 CEG39483.1 - 0.57 10.4 4.1 0.38 11.0 2.3 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 STAT_alpha PF01017.20 CEG39483.1 - 0.58 10.0 11.0 0.14 12.0 6.1 2.1 2 1 0 2 2 2 0 STAT protein, all-alpha domain DUF3450 PF11932.8 CEG39483.1 - 1.1 8.5 12.4 0.79 9.0 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF5320 PF17253.2 CEG39483.1 - 1.4 10.0 4.8 1.3 10.2 0.1 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5320) TPR_MLP1_2 PF07926.12 CEG39483.1 - 1.5 8.9 14.8 4.9 7.2 4.0 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Osmo_CC PF08946.10 CEG39483.1 - 1.7 9.0 5.7 0.75 10.1 1.5 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Spc24 PF08286.11 CEG39483.1 - 1.9 8.7 12.7 0.34 11.2 1.6 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 GCN5L1 PF06320.13 CEG39483.1 - 2.6 8.2 9.6 0.45 10.7 1.1 2.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) AAA_23 PF13476.6 CEG39483.1 - 2.7 8.5 13.1 6.6e+02 0.7 13.1 2.5 1 1 0 1 1 1 0 AAA domain FlxA PF14282.6 CEG39483.1 - 3.2 7.8 17.2 0.34 10.9 1.3 2.7 2 1 0 2 2 2 0 FlxA-like protein Cauli_AT PF03233.13 CEG39483.1 - 3.3 7.6 9.8 17 5.3 0.3 3.1 1 1 2 3 3 3 0 Aphid transmission protein RasGAP_C PF03836.15 CEG39483.1 - 3.6 7.7 10.1 1.5 9.0 1.6 2.7 3 1 0 3 3 3 0 RasGAP C-terminus APG6_N PF17675.1 CEG39483.1 - 7 7.2 15.4 4.5 7.8 6.7 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0449 PF15136.6 CEG39483.1 - 8.7 6.9 12.5 2.4 8.7 0.1 3.2 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 HALZ PF02183.18 CEG39484.1 - 0.0049 17.1 1.4 0.0079 16.4 1.4 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 CEG39484.1 - 0.009 15.8 0.9 0.016 15.0 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator FlaC_arch PF05377.11 CEG39484.1 - 0.02 15.3 0.9 0.075 13.4 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 CEG39484.1 - 0.03 14.8 7.2 0.052 14.0 7.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Fungal_TACC PF12709.7 CEG39484.1 - 0.15 12.5 4.2 0.3 11.6 4.2 1.5 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Oxysterol_BP PF01237.18 CEG39485.1 - 5.4e-45 153.8 0.0 1.1e-36 126.4 0.0 2.4 1 1 1 2 2 2 2 Oxysterol-binding protein START PF01852.19 CEG39485.1 - 7.2e-14 51.7 0.0 1.4e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 START domain PH PF00169.29 CEG39485.1 - 1.5e-11 44.7 0.0 5e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEG39485.1 - 3.3e-05 24.3 0.1 0.00011 22.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG39485.1 - 0.0098 16.2 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain EMC1_C PF07774.13 CEG39486.1 - 4e-51 173.7 0.3 9.3e-51 172.5 0.0 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CEG39486.1 - 9.6e-11 41.7 3.4 1.1e-07 31.7 1.0 2.6 2 0 0 2 2 2 2 PQQ-like domain DUF4335 PF14233.6 CEG39486.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF799 PF05643.11 CEG39486.1 - 0.3 10.6 1.6 1.8 8.1 0.1 2.4 2 1 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) Rubis-subs-bind PF09273.11 CEG39488.1 - 6.8e-19 68.8 1.0 1.2e-18 68.0 1.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 CEG39488.1 - 3.4e-07 30.8 0.0 6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF1818 PF08848.11 CEG39488.1 - 0.66 10.1 3.8 5.1 7.2 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1818) WD40 PF00400.32 CEG39489.1 - 1.1e-19 70.3 2.6 2e-06 28.4 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG39489.1 - 4.7e-09 36.4 0.0 0.35 11.2 0.0 5.4 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG39489.1 - 6.2e-08 32.0 3.9 0.016 14.2 0.0 4.8 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SpoIIIAH PF12685.7 CEG39489.1 - 0.00061 19.7 0.3 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 SpoIIIAH-like protein PD40 PF07676.12 CEG39489.1 - 0.02 14.8 0.3 1.2e+02 2.7 0.1 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 CEG39489.1 - 0.031 13.5 1.3 0.96 8.6 0.0 2.7 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Proteasome_A_N PF10584.9 CEG39489.1 - 0.65 9.7 3.9 22 4.8 0.2 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ALG3 PF05208.13 CEG39490.1 - 1.6e-136 455.4 28.9 2.1e-136 455.1 28.9 1.1 1 0 0 1 1 1 1 ALG3 protein Diphthamide_syn PF01866.17 CEG39491.1 - 8.3e-94 314.4 0.3 1.1e-93 314.0 0.3 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MOZART1 PF12554.8 CEG39492.1 - 6e-10 38.7 0.3 8.1e-10 38.3 0.3 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Pkinase PF00069.25 CEG39494.1 - 6.4e-69 232.3 0.0 7.6e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39494.1 - 7.2e-35 120.5 0.0 9.2e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG39494.1 - 1.9e-05 24.1 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG39494.1 - 0.037 13.0 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CENP-B_N PF04218.13 CEG39494.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain adh_short PF00106.25 CEG39495.1 - 2.7e-43 147.7 0.0 4.7e-43 146.9 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG39495.1 - 2.6e-29 102.5 0.0 3.3e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG39495.1 - 7.6e-06 26.0 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Glyco_hydro_92 PF07971.12 CEG39495.1 - 0.18 10.7 0.0 11 4.8 0.0 2.0 1 1 0 2 2 2 0 Glycosyl hydrolase family 92 Polysacc_synt_2 PF02719.15 CEG39495.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FHA PF00498.26 CEG39497.1 - 3e-20 72.3 0.6 9e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 FHA domain WD40 PF00400.32 CEG39497.1 - 1.9e-16 60.2 17.9 0.0012 19.6 0.0 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat Yop-YscD_cpl PF16697.5 CEG39497.1 - 2.4e-10 40.6 0.3 1.9e-09 37.7 0.0 2.7 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain ANAPC4_WD40 PF12894.7 CEG39497.1 - 3.6e-07 30.4 0.0 0.23 11.8 0.0 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1018 PF06252.12 CEG39497.1 - 0.018 16.1 1.5 0.035 15.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Ge1_WD40 PF16529.5 CEG39497.1 - 0.048 12.6 0.1 16 4.3 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4029 PF13221.6 CEG39502.1 - 0.035 14.7 0.1 0.038 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) Glyco_hydro_17 PF00332.18 CEG39504.1 - 1.9e-07 31.0 2.1 1.6e-05 24.7 1.1 2.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 zf_Hakai PF18408.1 CEG39505.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-met PF12874.7 CEG39505.1 - 0.089 13.2 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CEG39505.1 - 0.097 13.2 0.2 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Guanylate_cyc PF00211.20 CEG39507.1 - 4.4e-13 49.3 0.0 8.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SEEK1 PF15357.6 CEG39507.1 - 0.0083 16.3 0.2 5.1 7.2 0.0 2.3 2 0 0 2 2 2 2 Psoriasis susceptibility 1 candidate 1 DUF2637 PF10935.8 CEG39507.1 - 0.24 11.3 0.1 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Guanylate_cyc PF00211.20 CEG39508.1 - 3.4e-10 39.9 0.0 8.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Glyco_hydro_17 PF00332.18 CEG39509.1 - 2.4e-07 30.7 2.0 5e-07 29.6 0.9 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Ank_2 PF12796.7 CEG39513.1 - 5.2e-35 119.9 15.1 5.5e-07 30.1 0.7 7.6 2 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG39513.1 - 8.3e-33 112.3 27.0 4.1e-06 27.2 0.4 11.4 8 2 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG39513.1 - 6.9e-25 86.8 22.4 0.057 13.7 0.1 15.6 4 1 13 17 17 17 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG39513.1 - 2.4e-18 64.3 3.7 11 6.9 0.0 15.1 15 2 2 17 17 17 2 Ankyrin repeat Ank PF00023.30 CEG39513.1 - 3.9e-05 23.9 4.2 98 3.7 0.5 9.5 4 3 1 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 CEG39513.1 - 0.00017 22.1 11.2 4.6 7.8 0.0 7.6 8 0 0 8 8 8 2 Domain of unknown function (DUF1843) DUF4851 PF16143.5 CEG39513.1 - 0.09 12.2 0.3 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4851) Spy1 PF11357.8 CEG39513.1 - 0.12 12.6 0.1 0.59 10.4 0.1 2.1 2 0 0 2 2 2 0 Cell cycle regulatory protein ubiquitin PF00240.23 CEG39515.1 - 0.002 17.8 0.5 0.004 16.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Enterotoxin_b PF01376.18 CEG39515.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DWNN PF08783.11 CEG39515.1 - 0.097 13.0 0.3 0.19 12.0 0.3 1.5 1 0 0 1 1 1 0 DWNN domain ApoLp-III PF07464.11 CEG39516.1 - 0.033 14.3 0.2 0.046 13.8 0.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) OSCP PF00213.18 CEG39516.1 - 0.04 14.0 0.7 0.11 12.6 0.7 1.6 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF1640 PF07798.11 CEG39516.1 - 0.083 12.9 2.3 0.1 12.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4665 PF15679.5 CEG39516.1 - 2.3 8.9 9.1 0.41 11.3 5.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Gp_dh_C PF02800.20 CEG39517.1 - 3.8e-69 231.3 0.0 5.6e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEG39517.1 - 1.7e-38 131.0 0.1 4.3e-38 129.7 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CEG39517.1 - 0.0035 17.5 0.2 0.013 15.6 0.1 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 CEG39517.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 CEG39517.1 - 0.11 12.8 0.1 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain ABC2_membrane PF01061.24 CEG39520.1 - 5.8e-75 251.3 62.9 1.2e-41 142.4 26.2 2.7 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CEG39520.1 - 1.3e-33 116.4 0.0 2.8e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CEG39520.1 - 4.8e-07 29.2 58.1 4.8e-05 22.6 17.1 3.5 2 2 2 4 4 4 2 ABC-2 family transporter protein PDR_CDR PF06422.12 CEG39520.1 - 8.4e-07 28.8 0.1 9.6e-06 25.4 0.0 2.8 2 0 0 2 2 2 1 CDR ABC transporter AAA_16 PF13191.6 CEG39520.1 - 9.3e-07 29.4 0.0 0.0023 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEG39520.1 - 2.4e-06 27.5 2.3 0.013 15.5 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CEG39520.1 - 2.5e-06 27.1 2.1 0.45 9.9 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG39520.1 - 3.1e-06 26.8 3.4 0.011 15.4 0.7 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CEG39520.1 - 4.8e-06 26.6 0.1 0.81 9.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CEG39520.1 - 3e-05 23.4 0.1 0.0086 15.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CEG39520.1 - 4.3e-05 23.8 0.1 0.092 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEG39520.1 - 0.00012 21.9 0.3 0.58 9.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEG39520.1 - 0.00026 21.4 0.8 0.62 10.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEG39520.1 - 0.00038 20.1 0.9 0.71 9.4 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CEG39520.1 - 0.00087 19.9 0.7 0.22 12.0 0.4 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEG39520.1 - 0.0017 18.9 0.0 0.58 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 CEG39520.1 - 0.0035 17.3 0.4 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 CEG39520.1 - 0.0035 17.7 0.2 0.57 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 CEG39520.1 - 0.0067 16.5 1.7 0.88 9.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 CEG39520.1 - 0.0098 15.8 3.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CEG39520.1 - 0.02 15.0 0.0 9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEG39520.1 - 0.038 13.6 1.8 2.3 7.8 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEG39520.1 - 0.047 13.8 6.4 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 CEG39520.1 - 0.071 13.1 0.4 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CEG39520.1 - 0.083 13.2 0.1 21 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CEG39520.1 - 0.083 12.6 0.6 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CEG39520.1 - 0.13 12.0 1.5 10 5.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CEG39520.1 - 0.16 12.2 1.6 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CEG39520.1 - 0.27 11.2 1.7 6.3 6.8 0.3 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CEG39520.1 - 0.39 10.4 2.1 6.2 6.6 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CEG39520.1 - 0.45 10.7 2.5 23 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 CEG39520.1 - 1.6 8.6 12.9 0.26 11.0 1.7 3.3 3 0 0 3 3 2 0 Plant PDR ABC transporter associated RibD_C PF01872.17 CEG39522.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Sigma70_ner PF04546.13 CEG39522.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BLOC1_2 PF10046.9 CEG39522.1 - 0.14 12.5 1.3 0.22 11.9 0.5 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DNA_pol_A_exo1 PF01612.20 CEG39523.1 - 8e-23 81.0 0.6 8.3e-22 77.7 0.6 2.3 1 1 0 1 1 1 1 3'-5' exonuclease DNApol_Exo PF18136.1 CEG39523.1 - 0.018 14.2 0.1 0.033 13.3 0.1 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Hormone_1 PF00103.20 CEG39524.1 - 0.14 11.9 0.9 0.22 11.2 0.6 1.5 2 0 0 2 2 2 0 Somatotropin hormone family bZIP_Maf PF03131.17 CEG39524.1 - 0.77 10.3 8.4 0.34 11.5 5.6 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor zf-RING_9 PF13901.6 CEG39526.1 - 0.26 11.2 0.0 0.27 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Toxin_3 PF00537.18 CEG39530.1 - 0.064 13.5 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain DZR PF12773.7 CEG39531.1 - 0.11 12.6 5.5 2.9 8.0 5.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-UBP PF02148.19 CEG39531.1 - 3.8 7.9 9.0 0.11 12.9 1.4 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.21 CEG39531.1 - 5.6 7.2 10.6 19 5.5 10.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger Stc1 PF12898.7 CEG39531.1 - 8.6 7.0 10.2 0.29 11.7 3.3 2.0 2 0 0 2 2 2 0 Stc1 domain FYVE PF01363.21 CEG39532.1 - 0.63 10.2 9.9 1.8 8.7 9.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG39532.1 - 0.92 9.7 10.1 2.7 8.3 10.1 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 CEG39532.1 - 9 6.6 13.1 0.59 10.4 5.5 2.5 1 1 0 2 2 2 0 IBR domain, a half RING-finger domain Efg1 PF10153.9 CEG39534.1 - 5.4e-26 91.2 12.3 5.4e-26 91.2 12.3 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Ebp2 PF05890.12 CEG39534.1 - 0.094 12.3 18.9 0.016 14.8 7.8 2.3 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 Pkinase PF00069.25 CEG39535.1 - 2.1e-64 217.5 0.0 3.8e-41 141.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39535.1 - 2.3e-32 112.3 0.0 2.4e-26 92.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG39535.1 - 4.6e-06 26.1 0.2 0.004 16.5 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CEG39535.1 - 0.00011 21.7 0.0 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG39535.1 - 0.001 19.0 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG39535.1 - 0.026 13.5 0.1 0.057 12.4 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain PDZ_6 PF17820.1 CEG39535.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Seadorna_VP7 PF07387.11 CEG39535.1 - 0.046 12.8 0.1 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CEG39535.1 - 0.053 13.1 0.2 0.24 11.0 0.0 1.9 1 1 1 2 2 2 0 RIO1 family OrsD PF12013.8 CEG39535.1 - 0.2 12.1 1.1 0.64 10.5 0.2 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D CENP-T_C PF15511.6 CEG39536.1 - 1.7e-08 34.5 0.1 2.1e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEG39536.1 - 0.00019 21.7 0.1 0.00025 21.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CEG39536.1 - 0.0003 20.9 0.1 0.00042 20.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CEG39536.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEG39536.1 - 0.0046 17.3 0.2 0.0052 17.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CEG39536.1 - 0.027 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEG39536.1 - 0.053 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CEG39536.1 - 0.18 11.6 0.1 0.22 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 CEG39537.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 CEG39537.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CEG39537.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CEG39537.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEG39537.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEG39537.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CEG39538.1 - 1.9e-19 70.3 0.1 2.6e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CEG39538.1 - 0.0004 20.8 0.0 0.00067 20.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CEG39538.1 - 0.00085 19.6 0.1 0.0026 18.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CEG39538.1 - 0.013 15.5 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein Adaptin_N PF01602.20 CEG39539.1 - 4.8e-110 368.6 15.3 6.3e-110 368.2 15.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CEG39539.1 - 6.3e-49 166.0 0.5 1.5e-48 164.8 0.5 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CEG39539.1 - 4.8e-28 97.6 0.1 1.4e-27 96.1 0.1 1.9 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CEG39539.1 - 1.2e-15 57.7 5.2 4e-08 33.5 0.1 5.0 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 CEG39539.1 - 1.3e-12 48.1 16.6 5.4e-07 29.8 1.8 4.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEG39539.1 - 3.6e-06 26.8 7.3 4.8 7.7 0.0 6.4 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 CEG39539.1 - 0.0067 16.4 0.4 6.5 7.0 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG39539.1 - 0.014 15.9 4.5 42 4.8 1.2 4.7 4 1 0 4 4 3 0 HEAT-like repeat LXG PF04740.12 CEG39539.1 - 0.015 15.0 0.3 0.58 9.8 0.2 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily HEAT_PBS PF03130.16 CEG39539.1 - 0.062 14.0 2.4 26 5.9 0.2 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Alpha_adaptin_C PF02296.16 CEG39539.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain DNA_alkylation PF08713.11 CEG39539.1 - 0.16 11.6 2.4 1 9.0 0.4 2.8 3 1 0 3 3 3 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 CEG39539.1 - 1.4 9.6 9.8 3.7 8.2 0.1 4.8 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region Cupin_4 PF08007.12 CEG39540.1 - 6.3e-47 160.6 0.1 8.8e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CEG39540.1 - 5.5e-06 26.3 0.3 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 CEG39540.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 CEG39540.1 - 0.071 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ARD/ARD' family zf-CXXC PF02008.20 CEG39544.1 - 1.4e-12 47.4 27.3 1e-09 38.3 19.8 2.7 2 0 0 2 2 2 2 CXXC zinc finger domain DUF1340 PF07067.11 CEG39544.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) rve PF00665.26 CEG39545.1 - 3.6e-06 27.2 0.0 5.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG39545.1 - 4.8e-05 23.1 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Glyco_hydro81C PF17652.1 CEG39546.1 - 4.8e-10 39.2 0.1 5.6e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain cNMP_binding PF00027.29 CEG39548.1 - 2.2e-10 40.4 0.0 4.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ORF_12_N PF18042.1 CEG39549.1 - 0.14 12.6 0.4 0.66 10.4 0.1 1.9 1 1 0 2 2 2 0 ORF 12 gene product N-terminal Glyco_tran_10_N PF17039.5 CEG39550.1 - 0.046 14.2 0.2 0.17 12.3 0.2 1.9 2 0 0 2 2 2 0 Fucosyltransferase, N-terminal RhoGAP PF00620.27 CEG39550.1 - 0.068 13.0 0.5 0.16 11.8 0.5 1.6 1 0 0 1 1 1 0 RhoGAP domain Ferric_reduct PF01794.19 CEG39551.1 - 7.8e-17 61.6 10.4 7.8e-17 61.6 10.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG39551.1 - 4e-11 43.3 0.0 8.6e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DOMON PF03351.17 CEG39551.1 - 3.6e-08 33.7 0.1 8.7e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 DOMON domain FAD_binding_8 PF08022.12 CEG39551.1 - 8.8e-08 32.2 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CEG39551.1 - 2.2e-05 25.0 0.0 0.00096 19.8 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Mnd1 PF03962.15 CEG39552.1 - 5.8e-26 90.6 1.8 1e-25 89.7 0.1 2.3 3 0 0 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 CEG39552.1 - 1.2e-17 63.8 0.7 4e-17 62.0 0.7 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain DUF1664 PF07889.12 CEG39552.1 - 0.0048 16.9 1.0 0.0048 16.9 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CEG39552.1 - 0.057 13.0 1.5 0.059 12.9 1.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CEG39552.1 - 0.11 11.4 9.6 0.24 10.2 9.6 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Allexi_40kDa PF05549.11 CEG39552.1 - 0.12 11.9 0.8 0.18 11.3 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Tropomyosin_1 PF12718.7 CEG39552.1 - 0.12 12.6 13.9 0.032 14.4 10.9 1.5 2 0 0 2 2 2 0 Tropomyosin like TMPIT PF07851.13 CEG39552.1 - 0.32 10.2 3.6 0.46 9.7 3.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.6 CEG39552.1 - 0.85 10.1 7.7 1.2 9.6 7.7 1.3 1 0 0 1 1 1 0 AAA domain eIF3_N PF09440.10 CEG39552.1 - 1.3 9.4 7.2 0.96 9.9 4.8 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DUF4078 PF13300.6 CEG39552.1 - 1.5 9.2 13.4 1.8 9.0 2.8 2.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4078) Spc24 PF08286.11 CEG39552.1 - 1.9 8.8 8.3 0.15 12.3 3.2 1.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 CEG39552.1 - 2 7.4 12.0 3.5 6.6 12.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CEG39552.1 - 2.2 6.8 8.7 3.2 6.3 8.7 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A YkyA PF10368.9 CEG39552.1 - 2.2 7.9 12.0 0.4 10.3 8.5 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CoaE PF01121.20 CEG39553.1 - 1.5e-55 187.6 0.1 2.5e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CEG39553.1 - 1.8e-05 25.3 0.1 5.5e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG39553.1 - 0.0002 21.5 0.0 0.00058 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEG39553.1 - 0.0036 17.6 0.2 0.0064 16.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain DUF2325 PF10087.9 CEG39553.1 - 0.11 12.6 0.1 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) UPF0047 PF01894.17 CEG39555.1 - 6.7e-39 132.6 0.0 7.7e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Pinin_SDK_N PF04697.13 CEG39555.1 - 0.048 14.3 0.0 0.064 13.9 0.0 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region CLP_protease PF00574.23 CEG39555.1 - 0.073 12.9 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Clp protease Aa_trans PF01490.18 CEG39556.1 - 5.4e-39 134.1 33.2 6.8e-22 77.7 13.0 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein BT1 PF03092.16 CEG39557.1 - 1.2e-16 60.0 11.8 4.2e-12 45.1 1.1 2.4 3 0 0 3 3 3 2 BT1 family PUCC PF03209.15 CEG39557.1 - 0.0016 17.5 9.0 0.0059 15.7 0.2 2.3 2 0 0 2 2 2 2 PUCC protein DUF2628 PF10947.8 CEG39557.1 - 0.74 10.2 8.2 18 5.8 2.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) FXR_C3 PF16097.5 CEG39558.1 - 0.045 14.5 0.6 0.045 14.5 0.6 2.0 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 PTEN_C2 PF10409.9 CEG39559.1 - 2e-18 66.4 0.0 3.4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH PF00169.29 CEG39559.1 - 3.4e-17 62.9 0.0 7.9e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DSPc PF00782.20 CEG39559.1 - 3.2e-06 27.0 0.0 8.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEG39559.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEG39559.1 - 9.3e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PH_11 PF15413.6 CEG39559.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PTPlike_phytase PF14566.6 CEG39559.1 - 0.0083 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CEG39559.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 CEG39559.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Peptidase_S66C PF17676.1 CEG39559.1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain AAA_10 PF12846.7 CEG39561.1 - 0.0053 15.7 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CEG39561.1 - 0.035 14.0 0.0 0.097 12.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain CbiA PF01656.23 CEG39561.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HSP70 PF00012.20 CEG39562.1 - 7.7e-258 856.6 4.8 8.8e-258 856.4 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG39562.1 - 5.6e-17 61.5 0.1 6.9e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CEG39562.1 - 0.011 14.8 0.4 0.063 12.3 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 CEG39562.1 - 0.012 15.3 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.25 CEG39563.1 - 1.5e-63 214.6 0.0 2.9e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG39563.1 - 1e-46 159.4 0.0 1.6e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 CEG39563.1 - 1.7e-23 83.1 0.0 3.7e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 CEG39563.1 - 0.0005 18.9 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG39563.1 - 0.2 11.6 3.5 17 5.2 0.0 3.6 2 2 0 3 3 3 0 Phosphotransferase enzyme family FAM76 PF16046.5 CEG39563.1 - 8.4 5.7 8.2 12 5.1 3.7 2.6 3 0 0 3 3 3 0 FAM76 protein MYCBPAP PF14646.6 CEG39564.1 - 2.3e-60 204.8 0.4 2.3e-60 204.8 0.4 2.6 3 1 1 4 4 4 1 MYCBP-associated protein family PGK PF00162.19 CEG39564.1 - 1.4e-15 57.2 1.8 9.8e-08 31.3 0.1 3.9 3 1 0 3 3 3 3 Phosphoglycerate kinase Ectoine_synth PF06339.12 CEG39565.1 - 1.6e-18 67.1 0.0 1.9e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ectoine synthase RabGAP-TBC PF00566.18 CEG39566.1 - 6.5e-54 182.8 1.1 1e-53 182.2 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA_11 PF13086.6 CEG39566.1 - 0.12 12.2 3.7 0.7 9.6 4.0 1.9 2 0 0 2 2 2 0 AAA domain IL17 PF06083.11 CEG39566.1 - 1.6 9.2 6.6 2.8 8.5 0.5 3.0 3 0 0 3 3 3 0 Interleukin-17 Hydrolase_4 PF12146.8 CEG39567.1 - 7.2e-06 25.4 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 CEG39567.1 - 0.0046 16.6 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF900 PF05990.12 CEG39567.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 CEG39567.1 - 0.14 12.0 0.3 3.2 7.6 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase Ysc84 PF04366.12 CEG39568.1 - 1e-34 119.1 0.4 1.6e-34 118.4 0.4 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 CEG39568.1 - 5.7e-12 45.6 7.5 5.7e-12 45.6 7.5 2.8 3 0 0 3 3 3 1 FYVE zinc finger HypA PF01155.19 CEG39568.1 - 0.02 14.9 0.9 0.02 14.9 0.9 3.2 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LRR_6 PF13516.6 CEG39569.1 - 1.8e-16 58.7 4.8 0.00088 19.1 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CEG39569.1 - 0.0019 18.5 0.0 48 5.1 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 CEG39569.1 - 0.0039 17.6 7.0 0.016 15.6 0.4 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG39569.1 - 0.031 14.0 6.8 0.78 9.5 0.6 4.3 3 1 2 5 5 5 0 Leucine rich repeat Pro_isomerase PF00160.21 CEG39571.1 - 1.7e-51 174.6 0.0 2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_6 PF13516.6 CEG39572.1 - 4.4e-48 157.3 33.8 5.6e-05 22.9 0.2 16.9 16 0 0 16 16 16 13 Leucine Rich repeat LRR_1 PF00560.33 CEG39572.1 - 2.8e-10 39.3 3.7 2.4e+02 2.9 0.0 13.2 14 0 0 14 14 14 0 Leucine Rich Repeat LRR_4 PF12799.7 CEG39572.1 - 0.00056 20.3 26.9 4.2 7.9 0.0 10.0 9 3 5 14 14 14 5 Leucine Rich repeats (2 copies) FumaraseC_C PF10415.9 CEG39572.1 - 0.17 12.3 0.1 9.4 6.8 0.0 3.2 2 1 0 2 2 2 0 Fumarase C C-terminus LRR_8 PF13855.6 CEG39572.1 - 0.98 9.2 30.9 7.3 6.4 0.7 9.4 8 2 2 10 10 10 0 Leucine rich repeat Adaptin_N PF01602.20 CEG39573.1 - 1e-150 502.8 12.0 1.4e-150 502.4 12.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEG39573.1 - 4.5e-66 221.9 8.5 3.8e-65 218.9 0.1 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 BBL5 PF07289.11 CEG39573.1 - 6e-30 104.4 0.1 2.1e-29 102.6 0.1 1.8 2 0 0 2 2 2 1 Bardet-Biedl syndrome 5 protein B2-adapt-app_C PF09066.10 CEG39573.1 - 2.7e-18 66.1 0.0 1.4e-17 63.8 0.0 2.3 2 0 0 2 2 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CEG39573.1 - 5.3e-18 65.2 3.6 6.5e-05 23.2 0.0 5.6 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 CEG39573.1 - 3e-11 42.6 4.8 0.0023 18.0 0.0 6.0 6 0 0 6 6 5 2 HEAT repeat Cnd3 PF12719.7 CEG39573.1 - 2.8e-07 30.0 1.5 0.00011 21.5 0.1 2.7 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 CEG39573.1 - 3.7e-06 26.8 1.0 0.036 14.1 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 CEG39573.1 - 9.6e-06 25.9 2.8 2.6e-05 24.5 2.4 1.9 2 0 0 2 2 1 1 Adaptin C-terminal domain Arm_2 PF04826.13 CEG39573.1 - 1.3e-05 24.8 0.0 5.1e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Armadillo-like UNC45-central PF11701.8 CEG39573.1 - 6e-05 23.1 0.9 0.16 12.0 0.0 3.6 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central AP3B1_C PF14796.6 CEG39573.1 - 0.00022 21.5 0.0 0.00055 20.2 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal CLASP_N PF12348.8 CEG39573.1 - 0.00071 19.2 2.3 1.3 8.5 0.0 3.7 2 2 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 CEG39573.1 - 0.0012 18.9 3.7 0.92 9.7 0.0 4.8 2 2 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CEG39573.1 - 0.0017 18.8 1.1 3.3 8.3 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat DUF3157 PF11355.8 CEG39573.1 - 0.0039 16.9 0.3 0.019 14.6 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3157) DUF5578 PF17741.1 CEG39573.1 - 0.16 11.3 2.1 17 4.7 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5578) PH_TFIIH PF08567.11 CEG39573.1 - 0.19 12.1 0.5 1.3 9.4 0.0 2.6 3 0 0 3 3 2 0 TFIIH p62 subunit, N-terminal domain RasGEF_N_2 PF14663.6 CEG39573.1 - 0.28 11.6 2.1 23 5.5 0.0 4.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3361 PF11841.8 CEG39573.1 - 3.7 7.5 6.0 17 5.3 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) RVT_2 PF07727.14 CEG39574.1 - 2.6e-14 53.5 0.0 2.9e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEG39575.1 - 1.1e-17 64.0 1.0 1.6e-17 63.5 1.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG39575.1 - 4.9e-05 23.2 0.9 9e-05 22.4 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle TrwC PF08751.11 CEG39575.1 - 0.023 14.2 0.1 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 TrwC relaxase Aminotran_5 PF00266.19 CEG39576.1 - 1.2e-17 63.9 0.0 1.7e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PARG_cat PF05028.14 CEG39577.1 - 1.1e-95 320.8 0.1 1.5e-95 320.3 0.1 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) CCSMST1 PF15013.6 CEG39578.1 - 0.088 13.0 1.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 CCSMST1 family UBX PF00789.20 CEG39579.1 - 1.2e-11 44.7 0.0 2.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain MCD PF05292.11 CEG39579.1 - 0.01 15.4 3.2 0.016 14.8 3.2 1.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Macoilin PF09726.9 CEG39579.1 - 0.014 14.0 4.8 0.017 13.7 4.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF325 PF03804.13 CEG39579.1 - 0.14 12.2 0.8 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral proteins of unknown function Selenoprotein_S PF06936.11 CEG39579.1 - 2.2 8.0 13.5 3.5 7.4 13.5 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) ALMT PF11744.8 CEG39579.1 - 2.9 6.6 6.6 3.8 6.2 6.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4746 PF15928.5 CEG39579.1 - 3.2 7.1 12.1 4.7 6.6 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_23 PF13476.6 CEG39579.1 - 4.7 7.7 13.2 8.5 6.8 13.2 1.3 1 0 0 1 1 1 0 AAA domain DUF4554 PF15091.6 CEG39579.1 - 9.9 4.9 7.0 17 4.1 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Sua5_yciO_yrdC PF01300.18 CEG39580.1 - 1.1e-46 158.6 0.0 1.6e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CEG39580.1 - 2.8e-17 63.5 0.1 4.1e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding TTL PF03133.15 CEG39583.1 - 2e-59 201.1 1.6 3.5e-59 200.4 1.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEG39583.1 - 1.8e-11 43.8 0.1 1.4e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CEG39583.1 - 2.3e-05 23.8 0.0 0.047 12.9 0.1 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 CEG39583.1 - 0.059 13.0 0.1 10 5.7 0.0 2.7 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 CEG39583.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF812 PF05667.11 CEG39584.1 - 3.6e-107 359.7 27.7 6.1e-107 359.0 27.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF948 PF06103.11 CEG39584.1 - 0.0038 17.4 9.6 0.19 12.0 1.4 3.8 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 CEG39584.1 - 0.01 15.9 8.7 0.01 15.9 8.7 4.0 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase PSII_Pbs31 PF18240.1 CEG39584.1 - 0.016 15.6 1.9 0.058 13.8 1.9 1.9 1 0 0 1 1 1 0 Photosystem II Psb31 protein Adeno_E1B_19K PF01691.16 CEG39584.1 - 0.027 14.0 0.0 0.11 12.0 0.0 2.1 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen PRANC PF09372.10 CEG39584.1 - 0.14 12.5 2.1 0.34 11.3 1.4 2.1 1 1 0 1 1 1 0 PRANC domain KxDL PF10241.9 CEG39584.1 - 1.2 9.5 30.3 0.15 12.4 6.2 5.2 2 1 3 5 5 5 0 Uncharacterized conserved protein DUF2730 PF10805.8 CEG39584.1 - 4.8 7.3 24.8 0.055 13.6 7.8 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) DASH_Dad1 PF08649.10 CEG39584.1 - 5.3 7.3 10.3 1 9.6 0.9 3.5 4 0 0 4 4 4 0 DASH complex subunit Dad1 Baculo_PEP_C PF04513.12 CEG39584.1 - 6.1 6.9 16.1 0.77 9.8 0.4 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.15 CEG39584.1 - 6.6 6.7 10.4 1.8 8.5 1.9 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) APG17 PF04108.12 CEG39584.1 - 8.8 5.3 33.2 5.1 6.1 11.1 3.9 1 1 2 3 3 3 0 Autophagy protein Apg17 Myb_DNA-binding PF00249.31 CEG39585.1 - 2e-30 104.7 4.6 4.4e-16 58.8 0.5 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG39585.1 - 1.8e-21 76.2 0.5 1.1e-14 54.4 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG39585.1 - 1.8e-09 37.4 3.0 4.5e-06 26.5 0.0 3.1 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 CEG39585.1 - 0.00054 20.0 0.0 0.42 10.6 0.0 2.8 2 0 0 2 2 2 2 SLIDE Rap1_C PF11626.8 CEG39585.1 - 0.014 15.5 0.1 8.9 6.5 0.4 2.7 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 CEG39585.1 - 0.34 11.1 1.4 1 9.6 0.1 2.4 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 TTL PF03133.15 CEG39586.1 - 6.6e-98 327.5 2.7 7.8e-98 327.2 1.3 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEG39586.1 - 4.2e-08 32.8 0.0 0.0003 20.1 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CEG39586.1 - 2.5e-05 23.7 0.0 0.016 14.4 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp Ion_trans PF00520.31 CEG39587.1 - 1.6e-18 66.8 13.3 2.3e-18 66.3 13.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEG39587.1 - 3.7e-14 52.4 7.0 3.7e-14 52.4 7.0 3.1 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 CEG39587.1 - 0.0015 17.3 3.1 0.0027 16.5 3.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF3613 PF12266.8 CEG39588.1 - 0.0013 18.4 0.6 0.0039 16.9 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3613) TPR_1 PF00515.28 CEG39589.1 - 5e-11 41.9 3.2 0.001 18.8 0.0 4.0 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39589.1 - 1.8e-09 37.1 0.2 0.0021 18.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39589.1 - 2.4e-09 36.7 0.0 0.003 17.2 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CEG39589.1 - 6e-08 33.2 5.0 4.4e-05 24.0 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39589.1 - 1.2e-07 31.3 5.3 0.011 15.8 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39589.1 - 1.2e-05 25.7 3.2 0.00022 21.7 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39589.1 - 2.3e-05 24.8 3.6 0.43 11.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39589.1 - 2.5e-05 24.3 0.2 0.013 15.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG39589.1 - 5.3e-05 23.4 2.6 0.0023 18.2 0.5 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39589.1 - 0.00078 19.3 0.3 0.0039 17.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 CEG39589.1 - 0.0089 16.6 0.7 0.65 10.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG39589.1 - 0.013 15.7 0.4 0.051 13.8 0.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEG39589.1 - 0.03 14.2 0.1 0.15 12.0 0.0 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat DSPc PF00782.20 CEG39593.1 - 3.5e-16 59.2 0.0 5.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PNK3P PF08645.11 CEG39594.1 - 1.1e-52 178.0 0.4 7.8e-52 175.2 0.0 2.5 2 1 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CEG39594.1 - 2.4e-14 53.7 0.0 1.1e-11 45.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 CEG39594.1 - 1.6e-07 31.6 0.1 1.6e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Zeta_toxin PF06414.12 CEG39594.1 - 0.0013 18.1 0.0 1.3 8.3 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin BRCT PF00533.26 CEG39594.1 - 0.003 17.9 0.1 0.07 13.5 0.0 3.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 CEG39594.1 - 0.003 17.8 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEG39594.1 - 0.0084 16.1 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF4337 PF14235.6 CEG39594.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FAD_binding_2 PF00890.24 CEG39594.1 - 0.068 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RNA_helicase PF00910.22 CEG39594.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HSDR_N_2 PF13588.6 CEG39594.1 - 0.13 12.3 0.1 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Rad51 PF08423.11 CEG39597.1 - 2.1e-122 407.3 0.1 3.3e-122 406.6 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CEG39597.1 - 5.8e-12 45.6 0.1 8.4e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CEG39597.1 - 4.9e-11 42.6 0.1 8.1e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CEG39597.1 - 8.1e-09 36.0 1.9 3.6e-08 33.9 0.7 2.5 1 1 1 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 CEG39597.1 - 6.6e-07 28.9 2.2 9.6e-07 28.4 0.2 2.2 2 1 0 2 2 2 1 KaiC DnaB_C PF03796.15 CEG39597.1 - 1.2e-05 24.8 1.6 0.0013 18.1 0.0 2.9 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CEG39597.1 - 0.0032 17.2 0.0 0.008 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG39597.1 - 0.011 16.0 0.4 0.035 14.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain HHH PF00633.23 CEG39597.1 - 0.059 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 CEG39597.1 - 0.076 12.8 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PAXNEB PF05625.11 CEG39597.1 - 0.094 11.8 0.4 1.4 8.0 0.1 2.1 2 0 0 2 2 2 0 PAXNEB protein Methyltransf_25 PF13649.6 CEG39599.1 - 1.1e-34 119.0 0.1 3.4e-19 69.3 0.0 3.2 3 1 1 4 4 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 CEG39599.1 - 1.5e-34 118.5 0.1 6.5e-19 68.4 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEG39599.1 - 3.6e-29 101.7 0.0 2.2e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CEG39599.1 - 6e-28 97.6 0.1 8.6e-20 71.1 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEG39599.1 - 3.7e-22 78.9 0.1 1.2e-12 48.4 0.0 2.6 3 0 0 3 3 2 2 Methyltransferase domain CMAS PF02353.20 CEG39599.1 - 1.4e-20 73.7 0.2 7.3e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CEG39599.1 - 3e-16 59.5 0.0 3.4e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 CEG39599.1 - 2.9e-12 46.6 0.2 1.3e-09 37.9 0.0 2.7 3 0 0 3 3 3 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 CEG39599.1 - 2.1e-09 37.5 0.0 4.8e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEG39599.1 - 3.5e-09 36.4 0.0 0.00073 19.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain CheR PF01739.18 CEG39599.1 - 9.1e-09 35.1 0.0 0.0013 18.3 0.0 3.4 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain TPMT PF05724.11 CEG39599.1 - 1.4e-08 34.7 0.0 8.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 CEG39599.1 - 2.8e-08 33.2 0.0 4.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 CEG39599.1 - 7.9e-08 31.9 0.0 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TehB NodS PF05401.11 CEG39599.1 - 2.9e-06 27.1 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 CEG39599.1 - 0.0002 20.4 0.0 0.0077 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) MetW PF07021.12 CEG39599.1 - 0.00038 20.1 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Bin3 PF06859.12 CEG39599.1 - 0.00049 20.7 1.2 0.37 11.5 0.0 3.4 3 1 1 4 4 3 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_32 PF13679.6 CEG39599.1 - 0.0026 17.8 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CEG39599.1 - 0.0048 16.7 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein DOT1 PF08123.13 CEG39599.1 - 0.0059 16.2 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.13 CEG39599.1 - 0.011 15.1 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 CEG39599.1 - 0.013 14.6 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_4 PF02390.17 CEG39599.1 - 0.029 13.8 0.1 0.59 9.6 0.0 2.7 3 0 0 3 3 2 0 Putative methyltransferase Methyltransf_29 PF03141.16 CEG39599.1 - 0.053 12.1 0.0 0.19 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2461 PF09365.10 CEG39599.1 - 0.054 13.5 0.2 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) RabGAP-TBC PF00566.18 CEG39602.1 - 1.8e-24 86.6 7.7 1.1e-13 51.4 0.3 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain PH PF00169.29 CEG39602.1 - 1.6e-05 25.4 0.0 4.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG39602.1 - 0.039 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain TMEM223 PF14640.6 CEG39603.1 - 1.5e-15 57.8 0.2 1.2e-14 54.8 0.2 2.3 1 1 0 1 1 1 1 Transmembrane protein 223 MOSC_N PF03476.16 CEG39603.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain AHL_synthase PF17327.2 CEG39604.1 - 0.015 14.4 0.5 0.017 14.2 0.5 1.0 1 0 0 1 1 1 0 Acyl homoserine lactone synthase CALCOCO1 PF07888.11 CEG39605.1 - 0.0043 16.0 13.1 0.0047 15.9 13.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GP20 PF06810.11 CEG39605.1 - 0.0064 16.3 1.1 0.0099 15.7 1.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Rx_N PF18052.1 CEG39605.1 - 0.016 15.4 7.4 0.13 12.6 6.8 2.3 1 1 0 1 1 1 0 Rx N-terminal domain GAS PF13851.6 CEG39605.1 - 0.046 13.1 12.2 0.061 12.7 12.1 1.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 CEG39605.1 - 0.061 11.7 15.4 0.07 11.5 15.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein ATG16 PF08614.11 CEG39605.1 - 0.068 13.4 15.2 0.096 12.9 15.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) rhaM PF05336.13 CEG39605.1 - 0.19 11.8 4.2 0.22 11.6 2.0 1.9 1 1 1 2 2 2 0 L-rhamnose mutarotase Gp58 PF07902.11 CEG39605.1 - 0.75 8.0 7.2 0.81 7.9 7.2 1.1 1 0 0 1 1 1 0 gp58-like protein ADIP PF11559.8 CEG39605.1 - 0.82 9.7 20.2 1.7 8.7 15.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 CEG39605.1 - 0.95 9.5 14.5 1.4 9.0 14.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CEG39605.1 - 0.99 8.9 12.3 1.2 8.7 12.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 CEG39605.1 - 1 8.6 5.4 0.8 8.9 4.1 1.3 1 1 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 CEG39605.1 - 1.2 9.8 17.5 1 10.0 9.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 CEG39605.1 - 1.4 9.1 27.1 7.2 6.8 4.7 3.2 1 1 1 2 2 2 0 TolA binding protein trimerisation NBP1 PF08537.10 CEG39605.1 - 1.7 8.0 9.5 0.94 8.8 5.2 2.2 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 FUSC PF04632.12 CEG39605.1 - 5.9 5.3 8.0 6.6 5.1 8.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 CEG39605.1 - 8.4 5.6 18.5 15 4.8 8.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SNARE_assoc PF09335.11 CEG39606.1 - 3.1e-13 50.3 7.9 3.1e-13 50.3 7.9 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein SNARE_assoc PF09335.11 CEG39607.1 - 3.6e-16 59.7 4.4 3.6e-16 59.7 4.4 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein WLM PF08325.10 CEG39608.1 - 8.8e-41 140.1 0.0 1.8e-40 139.1 0.0 1.6 1 1 0 1 1 1 1 WLM domain PUB PF09409.10 CEG39608.1 - 1.3e-17 63.5 0.0 3.3e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 PUB domain DUF45 PF01863.17 CEG39608.1 - 0.00024 21.2 2.4 0.0012 19.0 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF45 Alph_Pro_TM PF09608.10 CEG39608.1 - 0.056 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TPH PF13868.6 CEG39609.1 - 4.6e-13 48.4 133.3 4.6e-13 48.4 133.3 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DDRGK PF09756.9 CEG39610.1 - 6.9e-55 185.6 32.8 6.9e-55 185.6 32.8 1.7 2 0 0 2 2 2 1 DDRGK domain Pkinase_fungal PF17667.1 CEG39610.1 - 0.015 14.1 5.0 0.022 13.6 5.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rrn6 PF10214.9 CEG39610.1 - 0.12 10.8 7.4 0.14 10.6 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4449 PF14613.6 CEG39610.1 - 0.92 9.6 14.8 1.9 8.6 14.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Exonuc_VII_L PF02601.15 CEG39610.1 - 1.2 8.6 9.5 1.5 8.3 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RR_TM4-6 PF06459.12 CEG39610.1 - 1.7 8.4 17.2 2.5 7.9 17.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Selenoprotein_S PF06936.11 CEG39610.1 - 2.9 7.7 21.4 5.8 6.7 21.4 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) PTPlike_phytase PF14566.6 CEG39611.1 - 1.4e-86 288.3 4.8 5e-47 159.9 0.8 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CEG39611.1 - 0.00012 22.1 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 CEG39611.1 - 0.00044 20.1 1.4 0.73 9.6 0.0 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG39611.1 - 0.017 14.7 0.2 1.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF4248 PF14053.6 CEG39611.1 - 0.096 12.7 0.0 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) rve PF00665.26 CEG39615.1 - 1.8e-13 50.8 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG39615.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_3 PF13358.6 CEG39615.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease 2-Hacid_dh_C PF02826.19 CEG39616.1 - 9.6e-45 152.1 0.0 3.2e-44 150.4 0.0 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEG39616.1 - 7.8e-29 100.0 0.0 8.9e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CHASE2 PF05226.11 CEG39616.1 - 0.11 12.2 0.0 1.1 8.9 0.0 2.0 1 1 0 2 2 2 0 CHASE2 domain DUF2039 PF10217.9 CEG39617.1 - 2.9e-28 98.0 14.9 6.2e-28 97.0 14.9 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) MS_channel PF00924.18 CEG39617.1 - 0.066 12.8 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel zinc-ribbons_6 PF07191.12 CEG39617.1 - 0.82 9.7 15.0 0.49 10.4 13.0 1.7 2 0 0 2 2 2 0 zinc-ribbons RVT_1 PF00078.27 CEG39618.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.24 CEG39619.1 - 1.3e-107 360.5 29.6 4.4e-82 276.3 16.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG39619.1 - 1.2e-28 100.1 28.8 1e-23 83.8 19.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEG39619.1 - 9.3e-05 21.0 0.9 0.00015 20.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PSI_integrin PF17205.3 CEG39619.1 - 0.069 12.9 3.6 0.19 11.5 3.6 1.7 1 0 0 1 1 1 0 Integrin plexin domain Sugar_tr PF00083.24 CEG39621.1 - 1.3e-113 380.2 21.4 5.4e-86 289.2 8.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG39621.1 - 1.6e-29 102.9 28.1 4.8e-28 98.1 15.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI_integrin PF17205.3 CEG39621.1 - 0.0027 17.4 2.6 0.0055 16.4 2.6 1.5 1 0 0 1 1 1 1 Integrin plexin domain TRI12 PF06609.13 CEG39621.1 - 0.0042 15.6 1.5 0.0042 15.6 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PSI PF01437.25 CEG39621.1 - 0.0047 17.4 7.7 0.0087 16.6 7.7 1.5 1 0 0 1 1 1 1 Plexin repeat MFS_3 PF05977.13 CEG39621.1 - 0.29 9.5 9.2 0.081 11.3 1.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector T3SchapCesA PF11439.8 CEG39623.1 - 0.048 13.8 0.1 0.048 13.8 0.1 3.3 4 0 0 4 4 4 0 Type III secretion system filament chaperone CesA CT_C_D PF02682.16 CEG39623.1 - 0.16 11.7 5.3 0.17 11.6 0.4 2.5 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D DUF1664 PF07889.12 CEG39623.1 - 0.17 11.9 24.9 0.59 10.2 3.1 4.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) MCM_N PF14551.6 CEG39623.1 - 0.31 11.7 11.6 0.61 10.7 1.5 2.9 1 1 2 3 3 3 0 MCM N-terminal domain Baculo_PEP_C PF04513.12 CEG39623.1 - 0.57 10.2 12.8 0.22 11.6 0.5 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 CEG39624.1 - 5.6e-25 87.1 11.9 6.5e-06 26.8 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG39624.1 - 4e-13 49.5 2.4 0.00068 19.9 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG39624.1 - 9.1e-05 22.4 0.1 0.00029 20.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CEG39624.1 - 0.00023 20.0 3.7 0.011 14.5 1.4 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 CEG39624.1 - 0.00093 18.2 0.3 0.046 12.7 0.0 2.8 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG39624.1 - 0.0072 15.0 2.5 0.017 13.8 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 IKI3 PF04762.12 CEG39624.1 - 0.024 12.6 0.2 0.097 10.7 0.1 1.9 2 1 0 2 2 2 0 IKI3 family A_deaminase PF00962.22 CEG39625.1 - 1e-52 179.6 0.2 5e-31 108.2 0.1 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CEG39625.1 - 0.014 14.8 0.4 0.05 12.9 0.4 1.8 2 1 0 2 2 2 0 Amidohydrolase family LPP PF04728.13 CEG39626.1 - 0.029 14.8 3.6 7 7.1 0.1 3.4 2 1 0 2 2 2 0 Lipoprotein leucine-zipper NPC1_N PF16414.5 CEG39627.1 - 4.1e-17 62.6 25.2 1.5e-16 60.7 25.2 1.9 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CEG39627.1 - 1.2e-15 57.7 13.4 1.2e-15 57.7 13.4 4.8 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEG39627.1 - 4.3e-14 51.6 25.6 4.3e-14 51.6 25.6 4.5 2 1 1 3 3 3 2 Patched family CPDase PF07823.11 CEG39627.1 - 0.0069 16.1 0.9 2.4 7.8 0.2 2.5 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein Synaptobrevin PF00957.21 CEG39627.1 - 0.68 9.8 17.5 0.39 10.5 0.4 3.8 3 0 0 3 3 3 0 Synaptobrevin WASH_WAHD PF11945.8 CEG39628.1 - 8.4e-40 137.1 0.2 2e-39 135.9 0.2 1.6 1 0 0 1 1 1 1 WAHD domain of WASH complex Exo_endo_phos PF03372.23 CEG39628.1 - 1.1e-25 90.5 0.0 3e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 CEG39628.1 - 6.7e-12 45.5 5.7 1.2e-11 44.7 5.7 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF737 PF05300.11 CEG39628.1 - 0.11 12.9 3.5 0.062 13.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) WH2 PF02205.20 CEG39628.1 - 0.11 12.3 0.2 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 WH2 motif zf-MYND PF01753.18 CEG39628.1 - 0.46 10.6 5.3 1.2 9.3 5.3 1.7 1 0 0 1 1 1 0 MYND finger BTB PF00651.31 CEG39629.1 - 1.4e-21 76.8 0.0 2.9e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CEG39629.1 - 3.9e-12 46.2 0.2 6.9e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch FAM176 PF14851.6 CEG39629.1 - 0.47 10.1 4.6 0.32 10.7 0.9 2.0 2 0 0 2 2 2 0 FAM176 family Syja_N PF02383.18 CEG39631.1 - 3.6e-83 279.5 0.0 1.8e-82 277.3 0.0 1.9 1 1 0 1 1 1 1 SacI homology domain AbiEi_4 PF13338.6 CEG39634.1 - 0.085 13.0 0.2 1.7 8.9 0.2 2.5 1 1 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin DUF4366 PF14283.6 CEG39636.1 - 0.045 13.8 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Thump_like PF18096.1 CEG39636.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 THUMP domain-like m04gp34like PF12216.8 CEG39636.1 - 0.17 11.4 0.1 0.17 11.4 0.1 1.0 1 0 0 1 1 1 0 Immune evasion protein Adeno_E3_CR2 PF02439.15 CEG39636.1 - 0.32 10.8 4.4 0.45 10.3 4.4 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CwsA PF10814.8 CEG39636.1 - 1.4 9.1 4.0 5.5 7.2 4.0 1.9 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA MFAP1 PF06991.11 CEG39637.1 - 2.8e-66 223.5 33.7 2.8e-66 223.5 33.7 2.2 2 0 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing DEAD PF00270.29 CEG39638.1 - 6.3e-38 130.3 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG39638.1 - 3.1e-24 85.5 0.3 3.5e-23 82.1 0.2 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG39638.1 - 5.2e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEG39638.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit NYN PF01936.18 CEG39639.1 - 2.3e-15 57.3 0.0 4.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain HVSL PF09749.9 CEG39640.1 - 1.8e-35 122.5 0.4 2.5e-35 122.1 0.2 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein HEPN_DZIP3 PF18738.1 CEG39640.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN MAGE PF01454.19 CEG39641.1 - 5.8e-18 65.4 0.0 1e-15 58.0 0.0 2.3 1 1 0 1 1 1 1 MAGE family GlcNAc PF11397.8 CEG39642.1 - 7.4e-29 101.3 0.6 1.1e-28 100.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) PAP2_3 PF14378.6 CEG39642.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF2678 PF10856.8 CEG39643.1 - 0.059 13.3 0.4 0.17 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) TetR_C_6 PF13977.6 CEG39644.1 - 0.041 14.1 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal PA PF02225.22 CEG39645.1 - 7.4e-10 38.7 0.2 1.8e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 CEG39645.1 - 3.5e-09 36.6 0.0 8.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 CEG39645.1 - 1.6e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Nicastrin PF05450.15 CEG39645.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Nicastrin PI3_PI4_kinase PF00454.27 CEG39646.1 - 2e-29 103.1 0.0 3.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MerR-DNA-bind PF09278.11 CEG39646.1 - 0.053 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 MerR, DNA binding RRM_1 PF00076.22 CEG39647.1 - 9.1e-18 63.9 0.0 1.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG39647.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CEG39647.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro81C PF17652.1 CEG39648.1 - 1e-76 258.5 4.2 1.6e-76 257.8 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG39648.1 - 1.1e-52 179.3 0.3 1.7e-52 178.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain PDEase_I PF00233.19 CEG39649.1 - 5.4e-55 186.7 0.4 3.5e-54 184.0 0.1 2.4 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CEG39649.1 - 6.2e-12 46.3 1.7 0.0004 21.0 0.0 4.8 4 0 0 4 4 4 4 GAF domain GAF_2 PF13185.6 CEG39649.1 - 7e-10 39.3 0.5 0.77 10.1 0.0 5.5 5 0 0 5 5 5 4 GAF domain Metallophos PF00149.28 CEG39650.1 - 3.5e-13 50.5 1.2 5.7e-13 49.8 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG39650.1 - 4.9e-07 30.5 1.5 1.8e-06 28.7 0.2 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CEG39650.1 - 1.6e-05 25.4 0.8 0.00021 21.8 0.3 2.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 CEG39650.1 - 0.00089 19.5 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Band_7 PF01145.25 CEG39653.1 - 2.4e-25 89.6 0.2 5.5e-25 88.4 0.2 1.7 1 0 0 1 1 1 1 SPFH domain / Band 7 family Fer2_3 PF13085.6 CEG39653.1 - 8.7e-21 74.0 0.1 2.3e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pur_ac_phosph_N PF16656.5 CEG39653.1 - 3.6e-20 72.3 0.1 1.7e-19 70.2 0.1 2.3 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 CEG39653.1 - 8e-12 46.1 5.0 2e-11 44.8 5.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG39653.1 - 7.1e-10 39.6 0.2 2e-09 38.1 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C YdfA_immunity PF12127.8 CEG39653.1 - 0.0057 15.8 1.1 0.0093 15.1 1.1 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Fer2 PF00111.27 CEG39653.1 - 0.063 13.2 0.5 0.18 11.8 0.5 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Paf67 PF10255.9 CEG39654.1 - 8.4e-114 380.7 5.4 2.2e-113 379.3 5.4 1.6 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 LCM PF04072.14 CEG39655.1 - 1.2e-32 113.4 0.0 3.9e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase La PF05383.17 CEG39656.1 - 7.5e-19 67.5 0.2 1.4e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CEG39656.1 - 0.0002 21.1 0.0 0.004 16.9 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4200 PF13863.6 CEG39658.1 - 3.5e-21 75.8 25.2 3.5e-21 75.8 25.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Med9 PF07544.13 CEG39658.1 - 0.00083 19.4 3.4 0.00083 19.4 3.4 4.1 2 1 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 Syntaxin-6_N PF09177.11 CEG39658.1 - 0.0017 18.9 25.0 0.028 15.0 6.3 3.7 2 1 1 3 3 3 2 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 CEG39658.1 - 0.0047 17.5 7.0 0.0047 17.5 7.0 3.7 3 1 1 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CEG39658.1 - 0.16 12.0 26.3 0.29 11.2 11.9 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3293 PF11697.8 CEG39658.1 - 0.47 11.0 3.4 0.62 10.6 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3293) KMP11 PF03037.16 CEG39658.1 - 1.6 9.5 11.6 1 10.2 9.2 2.0 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 MutS_III PF05192.18 CEG39658.1 - 8.5 6.6 22.4 0.24 11.6 4.7 2.5 2 1 0 2 2 2 0 MutS domain III Fez1 PF06818.15 CEG39658.1 - 8.5 6.8 34.1 6.7 7.1 17.6 2.6 1 1 1 2 2 2 0 Fez1 Utp12 PF04003.12 CEG39659.1 - 0.011 16.0 0.2 0.035 14.4 0.2 1.8 1 0 0 1 1 1 0 Dip2/Utp12 Family DEAD PF00270.29 CEG39660.1 - 1.5e-30 106.2 1.1 2.8e-21 76.1 0.5 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG39660.1 - 4.8e-29 100.9 2.3 3.6e-28 98.1 0.4 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CEG39660.1 - 0.00063 19.0 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RVT_2 PF07727.14 CEG39665.1 - 1.9e-48 165.2 0.2 2.3e-48 165.0 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM216B PF15107.6 CEG39665.1 - 0.098 12.5 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 FAM216B protein family TetR_C_18 PF17923.1 CEG39666.1 - 0.19 12.2 0.0 0.36 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LAMTOR5 PF16672.5 CEG39668.1 - 8.8e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 zf-C2H2 PF00096.26 CEG39669.1 - 9.1e-17 60.5 27.5 4.6e-05 23.6 1.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEG39669.1 - 4.3e-16 58.5 27.4 4.1e-06 27.0 1.3 5.3 5 0 0 5 5 5 4 Zinc-finger double domain BET PF17035.5 CEG39669.1 - 3.4e-10 39.9 0.0 7.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2_4 PF13894.6 CEG39669.1 - 2.1e-09 37.4 24.3 0.0021 18.7 1.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEG39669.1 - 4.4e-05 23.7 0.6 4.4e-05 23.7 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 CEG39669.1 - 0.00023 21.8 8.8 0.015 16.0 2.5 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger zf-met PF12874.7 CEG39669.1 - 0.011 16.1 0.7 0.011 16.1 0.7 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CEG39669.1 - 0.27 11.3 10.1 0.17 12.0 2.4 2.7 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 CEG39669.1 - 0.74 9.8 6.5 0.61 10.0 1.1 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CEG39669.1 - 5.4 7.4 13.2 1.4 9.2 1.8 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CEG39669.1 - 8.3 6.8 10.4 0.18 12.2 1.7 2.5 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RWP-RK PF02042.15 CEG39671.1 - 1.6e-20 72.8 2.2 5e-20 71.2 0.2 2.4 2 0 0 2 2 2 1 RWP-RK domain zf-C3HC4_2 PF13923.6 CEG39671.1 - 3.2e-10 39.7 9.9 3.2e-10 39.7 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG39671.1 - 2.3e-09 37.4 10.8 2.3e-09 37.4 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG39671.1 - 2.4e-09 36.9 6.0 2.4e-09 36.9 6.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG39671.1 - 7.3e-08 32.2 9.0 7.3e-08 32.2 9.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG39671.1 - 2.2e-07 30.8 4.8 2.2e-07 30.8 4.8 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG39671.1 - 8.9e-07 28.8 6.8 8.9e-07 28.8 6.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEG39671.1 - 1.4e-05 24.8 7.0 1.4e-05 24.8 7.0 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG39671.1 - 0.00042 20.4 11.5 0.00042 20.4 11.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CEG39671.1 - 0.0023 17.8 3.3 0.0055 16.5 3.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEG39671.1 - 0.0037 17.5 8.7 0.0037 17.5 8.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 CEG39671.1 - 0.017 15.1 4.7 0.017 15.1 4.7 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 CEG39671.1 - 0.16 11.3 1.6 0.16 11.3 0.2 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_11 PF17123.5 CEG39671.1 - 4 7.3 7.5 0.69 9.7 2.7 2.3 2 0 0 2 2 2 0 RING-like zinc finger GCN5L1 PF06320.13 CEG39672.1 - 6.6e-17 61.7 7.8 8.3e-17 61.4 7.8 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) JIP_LZII PF16471.5 CEG39672.1 - 0.032 14.4 2.5 0.053 13.7 2.4 1.5 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Radial_spoke_3 PF06098.11 CEG39672.1 - 0.34 10.2 6.8 0.42 9.8 6.8 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Cgr1 PF03879.14 CEG39672.1 - 0.57 10.6 8.9 1.4 9.3 7.6 2.0 1 1 1 2 2 2 0 Cgr1 family AAA_2 PF07724.14 CEG39673.1 - 3.3e-53 180.3 0.2 5.9e-50 169.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEG39673.1 - 3.7e-27 95.3 0.0 2.6e-14 53.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 CEG39673.1 - 3e-22 78.5 9.8 1.1e-21 76.7 2.9 3.0 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 CEG39673.1 - 5.6e-20 71.8 2.1 5.5e-14 52.3 0.0 3.7 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 CEG39673.1 - 1.7e-19 69.7 2.0 2.8e-19 68.9 0.2 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CEG39673.1 - 1.5e-14 53.8 2.4 6.3e-06 26.2 0.1 3.5 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CEG39673.1 - 5.7e-12 46.3 8.8 1.2e-05 25.8 0.1 4.8 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 CEG39673.1 - 4.4e-11 42.8 0.0 2e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain 2OG-FeII_Oxy_3 PF13640.6 CEG39673.1 - 5.6e-09 36.8 0.1 1.4e-08 35.5 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_22 PF13401.6 CEG39673.1 - 1.2e-08 35.3 3.0 0.0042 17.4 0.0 4.3 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CEG39673.1 - 1.1e-07 31.9 0.0 0.013 15.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEG39673.1 - 3.4e-07 30.2 0.0 0.0038 17.0 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CEG39673.1 - 2.3e-06 27.2 0.0 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 CEG39673.1 - 5.4e-06 26.5 9.2 0.62 9.9 0.2 5.2 5 1 0 5 5 5 3 ATPase domain predominantly from Archaea TniB PF05621.11 CEG39673.1 - 9.1e-06 25.2 0.0 0.0094 15.4 0.1 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 CEG39673.1 - 1.1e-05 26.0 2.3 0.039 14.5 0.0 3.6 4 0 0 4 4 2 2 AAA domain Mg_chelatase PF01078.21 CEG39673.1 - 2.8e-05 23.6 0.1 0.24 10.7 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CEG39673.1 - 4e-05 23.4 1.4 0.39 10.4 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CEG39673.1 - 7.1e-05 22.7 0.0 0.019 14.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CEG39673.1 - 0.00025 21.2 0.0 0.48 10.7 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 CEG39673.1 - 0.00034 20.3 0.0 0.092 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.6 CEG39673.1 - 0.00034 20.4 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit NACHT PF05729.12 CEG39673.1 - 0.00036 20.5 0.1 0.77 9.6 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_28 PF13521.6 CEG39673.1 - 0.00066 20.0 4.4 3.8 7.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 CEG39673.1 - 0.00073 19.9 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CEG39673.1 - 0.00076 19.7 0.0 0.79 9.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 CEG39673.1 - 0.0013 17.9 0.1 1.8 7.7 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 CEG39673.1 - 0.0016 18.4 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CEG39673.1 - 0.0028 17.6 0.8 3.7 7.4 0.0 3.3 4 0 0 4 4 2 1 RsgA GTPase ABC_tran PF00005.27 CEG39673.1 - 0.0044 17.5 0.8 1.8 9.1 0.0 4.0 4 0 0 4 4 3 1 ABC transporter Zeta_toxin PF06414.12 CEG39673.1 - 0.0046 16.2 0.2 0.33 10.2 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 CEG39673.1 - 0.0066 16.2 0.0 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CEG39673.1 - 0.0093 16.0 0.0 0.52 10.3 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CEG39673.1 - 0.01 15.0 0.3 0.03 13.4 0.3 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 CEG39673.1 - 0.036 14.6 0.0 0.036 14.6 0.0 4.4 2 2 0 2 2 1 0 AAA domain AAA_29 PF13555.6 CEG39673.1 - 0.041 13.6 0.0 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain GAD PF02938.14 CEG39673.1 - 0.045 14.0 0.2 0.89 9.8 0.0 3.2 3 0 0 3 3 2 0 GAD domain AbLIM_anchor PF16182.5 CEG39673.1 - 0.056 13.3 1.1 0.1 12.4 1.1 1.3 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM DUF87 PF01935.17 CEG39673.1 - 0.057 13.5 7.4 1.3 9.0 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_19 PF13245.6 CEG39673.1 - 0.15 12.4 1.4 1.9 8.8 0.1 3.2 2 2 0 2 2 2 0 AAA domain EMC3_TMCO1 PF01956.16 CEG39673.1 - 3.9 7.2 5.1 19 5.0 5.1 2.1 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ADH_zinc_N PF00107.26 CEG39674.1 - 5.2e-22 78.2 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEG39674.1 - 6.7e-13 49.8 0.0 1.2e-12 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEG39674.1 - 9.9e-11 41.5 0.1 1.5e-09 37.7 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CEG39674.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Rhabdo_matrix PF03397.14 CEG39675.1 - 0.02 14.6 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein Autophagy_act_C PF03987.15 CEG39676.1 - 4e-16 59.3 0.2 8e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain LMBR1 PF04791.16 CEG39677.1 - 4.2e-05 22.6 14.4 0.0016 17.5 3.3 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein DnaJ PF00226.31 CEG39678.1 - 3.8e-26 91.0 0.5 8e-26 90.0 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4472 PF14739.6 CEG39678.1 - 0.061 14.1 1.6 0.12 13.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DEAD PF00270.29 CEG39679.1 - 1.5e-46 158.3 0.5 3.1e-46 157.4 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG39679.1 - 1.3e-31 109.2 0.4 4.8e-31 107.4 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG39679.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEG39679.1 - 0.00052 20.4 1.0 0.0055 17.1 0.6 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG39679.1 - 0.00056 19.7 0.1 0.0009 19.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 CEG39679.1 - 0.0017 17.8 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CEG39679.1 - 0.019 13.8 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF1833 PF08875.11 CEG39679.1 - 0.04 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) UvrD-helicase PF00580.21 CEG39679.1 - 0.058 12.9 0.3 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 CEG39679.1 - 0.15 12.1 0.2 0.41 10.6 0.2 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain G_glu_transpept PF01019.21 CEG39681.1 - 7.4e-136 453.9 0.0 8.4e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Kazal_2 PF07648.15 CEG39683.1 - 8.6e-25 86.6 22.8 6.4e-10 39.0 2.8 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG39683.1 - 2.4e-22 78.7 21.8 8.4e-09 35.3 5.0 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain V-ATPase_C PF03223.15 CEG39684.1 - 1.8e-113 379.7 0.0 2.1e-113 379.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C COG2 PF06148.11 CEG39684.1 - 0.032 14.3 1.1 2.5 8.2 0.1 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MP PF01107.18 CEG39684.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) RWD PF05773.22 CEG39690.1 - 1.4e-20 73.7 0.9 2.4e-20 72.9 0.9 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CEG39690.1 - 1e-05 25.9 5.3 1e-05 25.9 5.3 2.2 1 1 2 3 3 3 1 DRG Family Regulatory Proteins, Tma46 TruB_C_2 PF16198.5 CEG39690.1 - 0.14 12.3 2.0 7.2 6.8 0.0 2.7 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain GWT1 PF06423.12 CEG39691.1 - 3.5e-27 95.4 8.5 3.5e-27 95.4 8.5 2.8 2 1 2 4 4 4 1 GWT1 HIG_1_N PF04588.13 CEG39691.1 - 1.5 9.1 7.4 0.57 10.5 1.9 3.1 2 1 1 3 3 3 0 Hypoxia induced protein conserved region FA_desaturase PF00487.24 CEG39692.1 - 8.6e-34 117.5 13.9 1.2e-33 117.0 13.3 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEG39692.1 - 1.6e-22 79.5 0.2 4.7e-20 71.5 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain m_DGTX_Dc1a_b_c PF17491.2 CEG39692.1 - 0.092 13.4 0.9 0.22 12.2 0.1 2.0 2 0 0 2 2 2 0 Spider Toxins mu-diguetoxin-1 a, b and c Jiv90 PF14901.6 CEG39692.1 - 0.095 12.9 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Ribosomal_L11_N PF03946.14 CEG39693.1 - 2.8e-19 68.7 0.2 3.8e-19 68.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEG39693.1 - 0.043 14.3 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain DMRL_synthase PF00885.19 CEG39694.1 - 1.3e-11 44.5 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DEAD PF00270.29 CEG39695.1 - 3.1e-50 170.3 0.1 4.7e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG39695.1 - 1.3e-31 109.2 0.0 1e-30 106.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG39695.1 - 3.5e-06 27.1 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEG39695.1 - 1.9e-05 24.0 0.0 3.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ANAPC15 PF15243.6 CEG39695.1 - 0.0099 16.3 0.6 0.019 15.3 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 SWI2_SNF2 PF18766.1 CEG39695.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Flavi_DEAD PF07652.14 CEG39695.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain API5 PF05918.11 CEG39695.1 - 4.9 5.9 5.5 6.6 5.4 5.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 CEG39696.1 - 8.5e-28 96.0 9.1 3.1e-06 27.8 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG39696.1 - 1.1e-17 64.1 3.8 1.4e-05 25.3 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG39696.1 - 7.4e-06 26.0 0.2 0.024 14.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEG39696.1 - 0.001 18.1 0.0 0.082 11.9 0.0 2.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C48 PF02902.19 CEG39697.1 - 0.016 15.0 0.2 0.05 13.4 0.2 1.8 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF1090 PF06476.12 CEG39697.1 - 0.047 13.8 1.9 0.097 12.8 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CDP-OH_P_transf PF01066.21 CEG39698.1 - 2.2e-15 57.2 0.2 2.2e-15 57.2 0.2 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3980 PF13140.6 CEG39698.1 - 3.2 8.3 7.2 0.35 11.3 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) Tis11B_N PF04553.12 CEG39700.1 - 0.095 13.3 0.1 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 Tis11B like protein, N terminus EF-hand_8 PF13833.6 CEG39701.1 - 3.4e-07 30.0 6.3 0.0011 18.7 3.4 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CEG39701.1 - 5.4e-07 30.0 5.0 9.2e-05 22.8 4.9 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG39701.1 - 2.7e-06 26.5 2.7 0.00044 19.6 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CEG39701.1 - 4.5e-05 23.0 1.4 0.00047 19.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_14 PF17959.1 CEG39701.1 - 0.004 17.5 0.1 0.0067 16.7 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain Yae1_N PF09811.9 CEG39705.1 - 3.4e-08 33.1 2.1 3.4e-08 33.1 2.1 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Pyr_redox_2 PF07992.14 CEG39706.1 - 5.3e-71 239.2 6.8 8.5e-71 238.6 6.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG39706.1 - 2.5e-37 127.5 0.2 6e-37 126.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEG39706.1 - 1.2e-18 67.5 9.0 2.1e-15 57.1 0.5 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEG39706.1 - 5.9e-12 45.4 6.9 4e-11 42.6 0.9 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CEG39706.1 - 1.4e-11 44.4 0.3 1.4e-11 44.4 0.3 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEG39706.1 - 2.3e-09 36.9 6.7 9.4e-07 28.4 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEG39706.1 - 1.2e-08 34.4 15.1 2e-06 27.2 2.0 4.0 3 1 2 5 5 5 2 FAD binding domain HI0933_like PF03486.14 CEG39706.1 - 1.6e-08 33.7 10.0 0.00019 20.3 1.4 4.1 4 0 0 4 4 4 3 HI0933-like protein NAD_binding_8 PF13450.6 CEG39706.1 - 2.3e-08 34.1 5.3 5.3e-05 23.4 0.3 3.3 2 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CEG39706.1 - 1.1e-07 31.4 1.6 0.0012 18.1 0.1 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CEG39706.1 - 3e-06 26.7 10.3 0.023 14.0 0.9 3.3 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 CEG39706.1 - 4.8e-06 25.9 2.4 0.017 14.3 0.1 3.1 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CEG39706.1 - 5.2e-06 25.9 1.4 0.00019 20.8 0.1 2.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 CEG39706.1 - 5.8e-05 22.3 0.9 0.0051 15.9 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 CEG39706.1 - 0.0054 16.4 19.0 0.45 10.0 0.1 4.2 2 2 1 4 4 4 2 FAD dependent oxidoreductase XdhC_C PF13478.6 CEG39706.1 - 0.01 16.4 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 CEG39706.1 - 0.048 13.0 0.3 0.89 8.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1133 PF06576.11 CEG39706.1 - 0.057 12.8 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) NAD_binding_7 PF13241.6 CEG39706.1 - 0.071 13.6 1.8 6 7.4 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CEG39706.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEG39706.1 - 1.6 8.2 5.2 0.38 10.3 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4650 PF15509.6 CEG39707.1 - 0.0036 16.7 1.1 0.0043 16.4 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4650) Ribosomal_L1 PF00687.21 CEG39708.1 - 2.4e-41 141.7 2.3 2.9e-41 141.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Herpes_HEPA PF03324.14 CEG39708.1 - 0.029 14.8 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein Helicase_C PF00271.31 CEG39708.1 - 0.14 12.5 0.2 2.1 8.7 0.1 2.3 1 1 1 2 2 2 0 Helicase conserved C-terminal domain Ank_2 PF12796.7 CEG39710.1 - 2.5e-22 79.2 6.2 5.6e-09 36.5 0.4 5.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG39710.1 - 4.9e-22 78.0 3.4 0.00084 19.9 0.0 6.4 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CEG39710.1 - 1.4e-14 53.7 1.1 0.0088 16.5 0.3 6.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CEG39710.1 - 5.1e-13 47.9 5.8 0.15 12.7 0.1 8.6 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 CEG39710.1 - 6e-12 45.6 2.0 0.011 16.1 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 CEG39710.1 - 0.00094 19.6 0.1 0.0028 18.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1843) Calreticulin PF00262.18 CEG39712.1 - 1.5e-87 293.8 17.0 4.6e-63 213.3 7.1 2.8 2 1 1 3 3 3 2 Calreticulin family RNA_pol_Rpc4 PF05132.14 CEG39712.1 - 1.2 9.5 8.1 2.9 8.3 8.1 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 CEG39712.1 - 2.1 8.4 5.3 3.8 7.6 5.3 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CEG39712.1 - 2.8 7.7 15.3 5.5 6.7 15.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CEG39712.1 - 8.5 5.0 10.5 11 4.7 10.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TMEM144 PF07857.12 CEG39713.1 - 4.3e-41 141.0 3.8 4.3e-41 141.0 3.8 2.2 2 1 0 2 2 2 1 Transmembrane family, TMEM144 of transporters DHHC PF01529.20 CEG39713.1 - 9.3e-20 71.1 8.3 9.3e-20 71.1 8.3 3.5 4 0 0 4 4 4 1 DHHC palmitoyltransferase PIG-Y PF15159.6 CEG39714.1 - 6.7e-19 68.6 4.0 1e-18 68.0 4.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DnaB_2 PF07261.11 CEG39716.1 - 0.0094 15.7 0.4 1.6 8.6 0.0 3.9 3 1 1 4 4 4 2 Replication initiation and membrane attachment Aldedh PF00171.22 CEG39717.1 - 5.3e-81 272.5 0.2 6.2e-81 272.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_Tyr PF07714.17 CEG39720.1 - 6.5e-20 71.5 0.0 6.8e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG39720.1 - 3.7e-18 65.8 0.0 3.9e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEG39720.1 - 9.2e-07 28.4 0.1 9.3e-07 28.4 0.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG39720.1 - 4.6e-05 23.5 0.1 5.1e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG39720.1 - 0.0059 15.6 0.1 0.0067 15.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEG39720.1 - 0.022 14.1 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 CEG39720.1 - 0.022 14.3 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 CEG39720.1 - 0.047 13.2 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CEG39720.1 - 0.17 11.4 0.0 2.4 7.7 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase GlcNAc PF11397.8 CEG39722.1 - 1.9e-72 244.7 0.2 1.3e-58 199.1 0.1 2.3 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 CEG39722.1 - 6.5e-15 55.8 0.0 1.2e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mtc PF03820.17 CEG39722.1 - 1.9e-09 37.0 0.1 2.6e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier 2OG-FeII_Oxy_4 PF13661.6 CEG39722.1 - 3e-09 37.4 0.0 8.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4423 PF14394.6 CEG39722.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) IKI3 PF04762.12 CEG39723.1 - 3.9e-155 518.3 12.7 1.6e-151 506.4 12.7 3.0 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CEG39723.1 - 0.0052 17.1 3.8 2 8.8 0.3 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PI3_PI4_kinase PF00454.27 CEG39724.1 - 1.3e-53 182.4 0.0 2.5e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEG39724.1 - 4.4e-47 159.9 2.8 8.3e-47 159.0 2.1 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CEG39724.1 - 0.0027 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PSS PF03034.15 CEG39725.1 - 6.1e-101 337.7 17.8 8.6e-101 337.3 17.8 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase AICARFT_IMPCHas PF01808.18 CEG39726.1 - 8.4e-82 274.9 0.0 1.2e-81 274.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CEG39726.1 - 1.4e-24 86.0 0.0 2.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Methyltransf_31 PF13847.6 CEG39727.1 - 6.4e-07 29.3 0.0 1.5e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain HTH_Tnp_Tc5 PF03221.16 CEG39727.1 - 1.2e-06 28.4 0.0 3.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2582 PF10771.9 CEG39727.1 - 0.058 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) CENP-B_N PF04218.13 CEG39727.1 - 0.15 11.8 0.1 19 5.0 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Y_phosphatase2 PF03162.13 CEG39728.1 - 3e-54 183.0 0.0 3.7e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEG39728.1 - 1.5e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEG39728.1 - 0.00037 20.1 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG39728.1 - 0.0044 16.8 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HhH-GPD PF00730.25 CEG39729.1 - 8.3e-22 77.7 0.0 1.4e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEG39729.1 - 4.3e-06 26.3 0.2 1.2e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif Kinesin_assoc PF16183.5 CEG39729.1 - 0.13 12.4 0.2 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Kinesin-associated DUF4479 PF14794.6 CEG39729.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) EndIII_4Fe-2S PF10576.9 CEG39729.1 - 1 9.8 4.1 1.9 8.9 4.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III MAPEG PF01124.18 CEG39730.1 - 2.6e-19 69.4 0.5 3.1e-19 69.2 0.5 1.1 1 0 0 1 1 1 1 MAPEG family CRT-like PF08627.10 CEG39731.1 - 3.5e-40 138.0 8.4 6.7e-40 137.1 8.4 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CEG39731.1 - 0.0076 16.4 3.1 0.0076 16.4 3.1 3.0 3 1 0 3 3 3 2 EamA-like transporter family URO-D PF01208.17 CEG39732.1 - 6.9e-120 400.3 0.0 8.1e-120 400.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF418 PF04235.12 CEG39732.1 - 0.07 13.1 0.9 0.097 12.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) CDC24_OB2 PF17245.2 CEG39733.1 - 0.019 15.6 0.1 0.024 15.2 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 Podoplanin PF05808.11 CEG39735.1 - 2.6e-06 27.6 0.6 2.6e-06 27.6 0.6 2.9 3 0 0 3 3 3 1 Podoplanin TMEM154 PF15102.6 CEG39735.1 - 0.00047 20.1 1.7 0.00047 20.1 1.7 3.3 3 2 0 3 3 3 1 TMEM154 protein family CD34_antigen PF06365.12 CEG39735.1 - 0.015 14.9 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 CEG39735.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 CEG39735.1 - 0.11 13.4 0.3 0.29 12.0 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 CEG39735.1 - 0.27 11.1 2.3 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 CEG39735.1 - 3.8 7.3 9.1 7.5 6.4 9.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 D123 PF07065.14 CEG39736.1 - 4.7e-82 275.6 0.0 6.7e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 D123 AMA-1 PF02430.15 CEG39736.1 - 0.093 11.7 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Synaptobrevin PF00957.21 CEG39737.1 - 2.4e-15 56.1 0.1 6.3e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Synaptobrevin DLIC PF05783.11 CEG39737.1 - 6.3e-06 25.3 0.0 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CEG39737.1 - 0.00017 22.0 0.0 0.00047 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CEG39737.1 - 0.0002 21.9 1.3 0.024 15.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA12 PF10443.9 CEG39737.1 - 0.00033 19.5 0.2 0.00099 17.9 0.0 1.9 2 0 0 2 2 2 1 RNA12 protein AAA_22 PF13401.6 CEG39737.1 - 0.00091 19.5 0.0 0.0037 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEG39737.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 CEG39737.1 - 0.0018 18.5 0.0 0.0061 16.8 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 CEG39737.1 - 0.0037 16.7 0.0 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CEG39737.1 - 0.0097 15.8 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CEG39737.1 - 0.011 16.2 0.0 0.07 13.6 0.0 2.3 2 0 0 2 2 1 0 ABC transporter DUF815 PF05673.13 CEG39737.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Longin PF13774.6 CEG39737.1 - 0.016 15.2 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Regulated-SNARE-like domain Ras PF00071.22 CEG39737.1 - 0.017 14.8 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Ras family ATPase_2 PF01637.18 CEG39737.1 - 0.035 14.0 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 CEG39737.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 CEG39737.1 - 0.093 12.9 0.0 2.9 8.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sipho_Gp157 PF05565.11 CEG39737.1 - 0.098 12.7 1.4 0.98 9.4 0.3 2.6 3 0 0 3 3 2 0 Siphovirus Gp157 AAA_7 PF12775.7 CEG39737.1 - 0.1 12.1 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CEG39737.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 CEG39737.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_15 PF13175.6 CEG39737.1 - 0.22 11.2 2.4 0.5 10.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_11 PF13086.6 CEG39737.1 - 3.8 7.2 0.0 3.8 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Proteasome PF00227.26 CEG39738.1 - 1.4e-31 109.5 0.0 1.7e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mannosyl_trans3 PF11051.8 CEG39740.1 - 6.5e-24 84.7 0.0 9.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 CEG39741.1 - 6.5e-37 127.4 0.2 1.6e-35 122.8 0.2 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 CEG39742.1 - 2.1e-36 125.7 0.0 2.2e-35 122.4 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Lip_prot_lig_C PF10437.9 CEG39746.1 - 0.22 11.5 1.3 5.4 7.1 0.1 3.4 2 1 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Baculo_PEP_C PF04513.12 CEG39746.1 - 0.24 11.5 42.0 4.2 7.4 0.8 5.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 CEG39746.1 - 0.83 9.4 29.6 28 4.4 14.6 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 CEG39746.1 - 1.6 8.8 29.2 1.1 9.4 7.8 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) PX PF00787.24 CEG39747.1 - 9e-06 25.6 0.2 5.3e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 PX domain Rep_1 PF01446.17 CEG39747.1 - 0.016 14.7 1.2 0.058 12.9 0.0 2.2 2 1 0 2 2 2 0 Replication protein PCRF PF03462.18 CEG39748.1 - 1.2e-56 191.7 0.1 2e-56 190.9 0.1 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CEG39748.1 - 5.7e-38 129.4 1.4 5.7e-38 129.4 1.4 2.2 2 0 0 2 2 2 1 RF-1 domain 2-oxoacid_dh PF00198.23 CEG39750.1 - 2.7e-78 262.6 0.1 3.8e-78 262.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEG39750.1 - 1.9e-37 126.9 11.6 1.5e-19 69.6 3.6 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme GCV_H PF01597.19 CEG39750.1 - 0.0017 18.3 5.7 0.17 11.8 0.9 2.6 2 0 0 2 2 2 2 Glycine cleavage H-protein HlyD_3 PF13437.6 CEG39750.1 - 0.0031 18.2 9.8 0.74 10.5 0.0 4.2 2 2 2 4 4 4 3 HlyD family secretion protein RnfC_N PF13375.6 CEG39750.1 - 0.029 14.3 5.2 0.16 11.9 0.4 3.0 3 1 0 3 3 3 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CEG39750.1 - 0.14 11.8 2.5 6.5 6.5 0.1 3.1 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain Biotin_lipoyl_2 PF13533.6 CEG39750.1 - 1.2 9.1 6.1 36 4.3 0.1 3.5 2 1 1 3 3 3 0 Biotin-lipoyl like Amidohydro_1 PF01979.20 CEG39751.1 - 2.7e-19 69.7 0.2 3.6e-19 69.3 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 CEG39751.1 - 0.00028 20.8 0.1 0.00048 20.0 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase zf-TRAF_2 PF15965.5 CEG39752.1 - 1e-07 32.3 0.8 0.0022 18.4 0.1 2.8 2 0 0 2 2 2 2 TRAF-like zinc-finger PAP_assoc PF03828.19 CEG39752.1 - 1.3e-05 25.3 0.6 0.00033 20.8 0.6 3.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEG39752.1 - 0.00017 21.8 0.0 0.00065 19.9 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-TRAF PF02176.18 CEG39752.1 - 0.0035 18.0 1.6 0.76 10.5 0.1 2.8 2 0 0 2 2 2 2 TRAF-type zinc finger Polbeta PF18765.1 CEG39752.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase VGCC_beta4Aa_N PF12052.8 CEG39752.1 - 0.028 14.5 1.7 0.22 11.7 1.7 2.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DEAD_2 PF06733.15 CEG39753.1 - 1.3e-50 171.5 0.9 2.4e-50 170.6 0.2 1.9 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 CEG39753.1 - 5.7e-41 140.5 0.0 1.2e-40 139.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 CEG39753.1 - 2.1e-36 125.4 1.7 1.4e-30 106.4 0.7 3.0 2 1 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CEG39753.1 - 8.8e-07 29.1 0.1 0.0002 21.4 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG39753.1 - 5.6e-05 23.0 0.4 0.009 15.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 CEG39753.1 - 0.026 13.2 0.1 4.6 5.8 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.9 CEG39753.1 - 0.063 12.5 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEG39753.1 - 0.2 11.1 0.1 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_L5 PF00281.19 CEG39754.1 - 6.9e-22 77.5 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 CEG39754.1 - 7.7e-22 77.3 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus fn3 PF00041.21 CEG39755.1 - 4.3e-08 33.4 1.0 0.12 12.7 1.4 4.1 2 2 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG39755.1 - 3.3e-05 24.4 0.3 0.015 15.8 0.2 2.9 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain MYO10_CC PF16735.5 CEG39756.1 - 0.032 14.3 1.1 0.032 14.3 1.1 7.7 9 1 1 10 10 10 0 Unconventional myosin-X coiled coil domain LRR_6 PF13516.6 CEG39756.1 - 0.061 13.4 0.1 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat DUF2208 PF09973.9 CEG39756.1 - 0.063 12.9 0.9 0.19 11.3 0.9 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Saccharop_dh_N PF04455.12 CEG39756.1 - 6.6 7.2 9.9 6.9 7.1 0.1 3.6 3 1 1 4 4 4 0 LOR/SDH bifunctional enzyme conserved region DUF4954 PF16314.5 CEG39757.1 - 4.5e-49 167.2 1.0 5.9e-49 166.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DNA_pol_B PF00136.21 CEG39758.1 - 4e-139 464.3 0.1 5.1e-139 463.9 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEG39758.1 - 7.8e-80 268.5 0.0 1.1e-79 268.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CEG39758.1 - 1.1e-17 64.3 5.6 2.2e-17 63.3 5.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CEG39758.1 - 0.078 11.8 1.1 0.48 9.2 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral ELMO_CED12 PF04727.13 CEG39761.1 - 1.8e-33 116.1 0.0 3.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.19 CEG39761.1 - 1.4e-17 63.9 0.0 3.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 RUN domain RhoGAP PF00620.27 CEG39761.1 - 3.2e-15 56.3 0.0 6.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain UCH PF00443.29 CEG39762.1 - 0.0065 16.0 0.3 0.0075 15.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF5349 PF17298.2 CEG39762.1 - 0.024 14.4 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Mitoc_mL59 PF18126.1 CEG39762.1 - 0.48 10.7 7.9 0.49 10.7 1.3 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein mL59 DUF4660 PF15559.6 CEG39762.1 - 3.2 8.1 6.0 0.27 11.6 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4660) DUF5609 PF18429.1 CEG39769.1 - 0.16 11.8 0.0 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) Retrotran_gag_2 PF14223.6 CEG39770.1 - 2.9e-17 62.6 5.6 7.4e-13 48.3 0.3 2.3 2 1 1 3 3 3 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG39770.1 - 0.0051 16.5 1.5 0.028 14.1 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) PPV_E2_C PF00511.17 CEG39772.1 - 0.011 15.9 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 E2 (early) protein, C terminal Fibrillarin PF01269.17 CEG39775.1 - 2.8e-107 357.0 0.0 3.5e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CEG39775.1 - 9.3e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CEG39775.1 - 0.0097 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TBP PF00352.21 CEG39776.1 - 2.4e-08 33.8 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF872 PF05915.12 CEG39778.1 - 0.024 14.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) E1-E2_ATPase PF00122.20 CEG39781.1 - 1.4e-24 86.6 0.5 3.3e-24 85.4 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEG39781.1 - 2.8e-15 57.2 0.0 1.4e-07 32.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 CEG39781.1 - 7.2e-07 29.4 0.2 2e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 CEG39781.1 - 8.4e-07 29.0 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEG39781.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MASE3 PF17159.4 CEG39781.1 - 0.045 13.4 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Membrane-associated sensor domain rve PF00665.26 CEG39783.1 - 7.2e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain AP3D1 PF06375.11 CEG39783.1 - 0.36 11.0 5.5 0.75 10.0 5.5 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 RRM_1 PF00076.22 CEG39784.1 - 8.6e-18 63.9 0.0 2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CEG39784.1 - 2.3e-12 46.5 25.6 0.0001 22.2 3.6 3.3 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 CEG39784.1 - 5.3e-11 42.1 21.6 3e-06 27.0 3.7 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG39784.1 - 2.7e-09 36.6 18.9 9.7e-05 22.1 0.3 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 CEG39784.1 - 3.8e-09 37.2 15.7 0.00025 21.7 0.5 4.2 2 1 2 4 4 4 3 Torus domain zf-CCCH_2 PF14608.6 CEG39784.1 - 7.7e-05 23.0 17.2 0.053 14.0 0.3 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CEG39784.1 - 0.0075 16.5 16.4 0.018 15.2 3.6 3.2 3 2 0 3 3 3 2 Zinc-finger containing family RRM_7 PF16367.5 CEG39784.1 - 0.0083 16.2 0.0 0.046 13.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif zf-like PF04071.12 CEG39784.1 - 2.3 8.2 8.6 5.6 7.0 0.2 2.6 1 1 1 2 2 2 0 Cysteine-rich small domain CLIP PF12032.8 CEG39784.1 - 3.4 8.0 5.9 6.7 7.1 0.2 3.3 1 1 2 3 3 3 0 Regulatory CLIP domain of proteinases UAA PF08449.11 CEG39785.1 - 5.3e-62 209.7 13.6 6.1e-62 209.5 13.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEG39785.1 - 2.5e-10 40.7 20.1 5.9e-05 23.3 10.1 2.9 2 2 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEG39785.1 - 3e-05 23.4 4.3 0.014 14.6 0.1 2.4 1 1 1 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 CEG39785.1 - 0.00039 19.9 8.4 0.038 13.3 2.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 CEG39785.1 - 0.0022 17.2 6.1 0.011 14.9 0.1 2.5 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 CEG39785.1 - 0.0023 16.9 0.9 0.0023 16.9 0.9 2.7 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF2839 PF10999.8 CEG39785.1 - 0.46 10.9 3.7 2.1 8.8 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Multi_Drug_Res PF00893.19 CEG39785.1 - 5.7 7.7 8.2 0.48 11.1 0.4 3.2 3 1 0 3 3 3 0 Small Multidrug Resistance protein Kinesin PF00225.23 CEG39786.1 - 6.1e-101 337.7 2.4 2.5e-100 335.7 2.4 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG39786.1 - 1.8e-21 76.6 0.0 9.2e-19 67.9 0.0 3.0 1 1 0 1 1 1 1 Microtubule binding MAP65_ASE1 PF03999.12 CEG39786.1 - 1.4e-05 24.0 2.2 1.4e-05 24.0 2.2 3.6 3 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) DUF1798 PF08807.10 CEG39786.1 - 0.0099 16.0 0.7 1 9.6 0.0 3.9 3 0 0 3 3 3 1 Bacterial domain of unknown function (DUF1798) AAA_7 PF12775.7 CEG39786.1 - 0.024 14.1 0.2 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SpoIISA_toxin PF14171.6 CEG39786.1 - 0.037 13.7 0.1 0.14 11.8 0.1 2.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Baculo_PEP_C PF04513.12 CEG39786.1 - 0.46 10.5 4.6 0.43 10.6 0.1 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin-VI_CBD PF16521.5 CEG39786.1 - 2 8.5 5.1 21 5.2 0.1 3.2 3 0 0 3 3 3 0 Myosin VI cargo binding domain Chorismate_bind PF00425.18 CEG39788.1 - 8.7e-86 287.7 0.0 1.6e-85 286.8 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CEG39788.1 - 8.8e-38 130.0 0.1 2.5e-37 128.5 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CEG39788.1 - 1e-15 58.2 0.0 2.2e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CEG39788.1 - 9.1e-12 45.2 0.1 1.9e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 FACT-Spt16_Nlob PF14826.6 CEG39788.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain FKBP_C PF00254.28 CEG39789.1 - 5.3e-20 71.5 0.7 1e-19 70.6 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Presenilin PF01080.17 CEG39789.1 - 1.1 7.9 15.5 1.5 7.5 15.5 1.2 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CEG39792.1 - 1.4e-06 28.6 1.4 1.6e-06 28.4 1.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Peptidase_M14 PF00246.24 CEG39793.1 - 1.1e-48 166.5 0.0 2.1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_6 PF01341.17 CEG39793.1 - 1.7e-40 139.7 5.8 1.7e-40 139.7 5.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 6 DUF4381 PF14316.6 CEG39793.1 - 0.049 13.9 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Enkurin PF13864.6 CEG39794.1 - 4.7e-26 91.1 4.8 6.7e-26 90.6 4.8 1.2 1 0 0 1 1 1 1 Calmodulin-binding DUF2630 PF10944.8 CEG39794.1 - 3.5 8.2 7.0 0.35 11.4 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) COMM_domain PF07258.14 CEG39795.1 - 1.7e-14 53.7 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 COMM domain Ribonucleas_3_2 PF11469.8 CEG39795.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III RabGAP-TBC PF00566.18 CEG39797.1 - 2.2e-53 181.1 1.5 3.3e-53 180.5 1.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 CEG39797.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) E1-E2_ATPase PF00122.20 CEG39798.1 - 8.2e-52 175.3 1.7 8.2e-52 175.3 1.7 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEG39798.1 - 4.5e-49 166.6 2.0 4.5e-49 166.6 2.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CEG39798.1 - 1.2e-20 72.9 0.2 9.4e-20 70.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CEG39798.1 - 4.4e-19 69.6 0.6 1.5e-17 64.6 0.6 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG39798.1 - 2.3e-18 66.1 0.1 4.7e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEG39798.1 - 0.00017 21.5 0.6 0.00039 20.2 0.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase VATC PF18716.1 CEG39799.1 - 0.99 9.3 4.3 2.7 7.9 4.3 1.7 1 1 0 1 1 1 0 Vms1-associating treble clef domain Actin PF00022.19 CEG39800.1 - 4.4e-111 371.4 0.0 4.8e-110 368.0 0.0 1.9 1 1 0 1 1 1 1 Actin Ribonuclease_3 PF00636.26 CEG39801.1 - 2.8e-32 111.5 0.0 1.9e-14 54.1 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CEG39801.1 - 1.2e-20 73.9 0.1 2e-09 37.7 0.0 4.5 4 1 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 CEG39801.1 - 2.2e-19 69.4 0.0 2.2e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 CEG39801.1 - 0.00026 20.8 0.0 0.00081 19.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase EF-hand_7 PF13499.6 CEG39803.1 - 2.4e-38 130.4 45.5 6.7e-10 39.3 0.7 8.9 7 1 2 9 9 9 8 EF-hand domain pair EF-hand_6 PF13405.6 CEG39803.1 - 4.9e-37 122.7 35.8 2.3e-06 27.1 0.1 12.9 12 0 0 12 12 12 11 EF-hand domain EF-hand_1 PF00036.32 CEG39803.1 - 4.4e-36 119.7 32.3 1.1e-06 27.8 0.1 12.0 12 0 0 12 12 12 9 EF hand EF-hand_8 PF13833.6 CEG39803.1 - 4e-22 77.8 36.4 1.9e-05 24.4 0.6 9.2 9 0 0 9 9 9 7 EF-hand domain pair EF-hand_5 PF13202.6 CEG39803.1 - 1.3e-11 43.5 26.7 0.03 13.8 0.1 10.7 11 0 0 11 11 11 5 EF hand T2SSF PF00482.23 CEG39803.1 - 0.04 13.9 0.3 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F EF-hand_11 PF08976.11 CEG39803.1 - 0.19 12.6 4.3 4.2 8.3 0.1 4.6 5 0 0 5 5 5 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG39803.1 - 0.3 11.4 13.6 0.32 11.3 0.1 5.9 6 1 0 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CEG39803.1 - 0.66 9.9 7.1 3.5 7.5 0.1 4.8 5 0 0 5 5 5 0 Caleosin related protein EF-hand_4 PF12763.7 CEG39803.1 - 1.9 8.5 6.9 97 3.0 0.0 5.2 4 2 2 6 6 6 0 Cytoskeletal-regulatory complex EF hand JAB PF01398.21 CEG39804.1 - 5.7e-21 74.7 0.1 1.1e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CEG39804.1 - 2.6e-20 72.9 0.1 2.3e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF4296 PF14129.6 CEG39805.1 - 0.003 18.1 2.2 0.057 14.0 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4296) DUF2922 PF11148.8 CEG39805.1 - 0.017 14.9 0.5 0.79 9.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) hGDE_N PF14699.6 CEG39805.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DUF3211 PF11485.8 CEG39805.1 - 0.035 14.3 0.3 0.071 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) Ubiq-assoc PF09145.10 CEG39805.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-associated RVT_2 PF07727.14 CEG39808.1 - 8.1e-25 87.9 0.0 3.2e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Dus PF01207.17 CEG39809.1 - 9.4e-58 195.7 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CEG39809.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein TIM PF00121.18 CEG39809.1 - 0.05 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase Sds3 PF08598.11 CEG39810.1 - 1.1e-07 32.0 7.0 1.1e-07 32.0 7.0 1.9 1 1 1 2 2 2 1 Sds3-like DUF3226 PF11536.8 CEG39810.1 - 0.0055 16.4 0.6 0.0099 15.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) Pedibin PF08182.11 CEG39810.1 - 1.7 8.5 6.2 1.8 8.4 0.4 3.3 3 0 0 3 3 3 0 Pedibin/Hym-346 family Aquarius_N PF16399.5 CEG39811.1 - 3.2e-100 336.4 13.6 9e-99 331.6 13.6 2.1 1 1 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CEG39811.1 - 1.4e-27 97.1 0.6 6.3e-27 95.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CEG39811.1 - 9.5e-27 93.9 0.0 2.1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEG39811.1 - 2.9e-08 33.7 0.1 0.00016 21.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CEG39811.1 - 4e-07 30.5 0.0 3.2e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG39811.1 - 2.7e-05 24.6 1.7 0.00055 20.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain UvrD-helicase PF00580.21 CEG39811.1 - 4.7e-05 23.1 1.2 0.00018 21.2 0.1 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CEG39811.1 - 9.2e-05 22.7 0.0 0.0004 20.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 CEG39811.1 - 0.00025 21.1 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CEG39811.1 - 0.001 18.7 0.0 0.0045 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG39811.1 - 0.0011 19.4 0.0 0.0055 17.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CEG39811.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CEG39811.1 - 0.0071 16.3 0.2 0.31 10.9 0.0 2.9 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.16 CEG39811.1 - 0.0079 15.7 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.6 CEG39811.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEG39811.1 - 0.019 15.5 0.0 0.067 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 CEG39811.1 - 0.041 13.6 0.0 16 5.1 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CEG39811.1 - 0.056 13.8 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.14 CEG39811.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 CEG39811.1 - 0.067 12.3 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase IL31 PF15209.6 CEG39811.1 - 0.12 12.2 0.2 0.47 10.2 0.2 2.1 1 0 0 1 1 1 0 Interleukin 31 Helicase_RecD PF05127.14 CEG39811.1 - 0.13 12.1 0.1 0.87 9.4 0.0 2.4 2 1 1 3 3 3 0 Helicase PAC2 PF09754.9 CEG39812.1 - 3.5e-13 50.1 0.0 4.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family PDDEXK_1 PF12705.7 CEG39815.1 - 1.6e-26 93.8 0.1 4e-26 92.5 0.1 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C PF13361.6 CEG39815.1 - 0.0063 15.9 0.0 1.8 7.8 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Dna2 PF08696.11 CEG39815.1 - 0.01 15.6 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 DNA replication factor Dna2 Csa1 PF06023.12 CEG39815.1 - 0.025 14.0 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Ribosomal_S13_N PF08069.12 CEG39816.1 - 1.7e-32 111.3 0.5 3.1e-32 110.4 0.5 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CEG39816.1 - 2.4e-15 56.5 2.1 3.2e-15 56.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 GBP_C PF02841.14 CEG39817.1 - 0.012 15.1 9.3 0.014 14.8 9.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ferric_reduct PF01794.19 CEG39818.1 - 1.3e-21 77.1 7.9 4.6e-21 75.2 7.9 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG39818.1 - 3.8e-15 56.3 0.0 1e-14 55.0 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG39818.1 - 7.1e-14 51.8 0.1 1.5e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4598 PF15370.6 CEG39819.1 - 2.5e-17 63.4 6.0 3.1e-17 63.1 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Isy1 PF06246.12 CEG39820.1 - 8.8e-75 251.6 9.7 1.1e-74 251.3 9.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF2895 PF11444.8 CEG39820.1 - 0.0029 17.0 1.9 0.016 14.6 1.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2895) Pyr_redox_2 PF07992.14 CEG39821.1 - 1.5e-49 168.8 0.7 5.9e-49 166.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG39821.1 - 1.5e-24 86.3 1.6 2.2e-24 85.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEG39821.1 - 9.3e-19 67.8 0.3 6.7e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG39821.1 - 2.6e-08 33.5 0.0 0.0074 15.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG39821.1 - 4.6e-08 32.2 2.3 0.00029 19.7 0.1 3.4 4 0 0 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 CEG39821.1 - 9.8e-08 31.7 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEG39821.1 - 1.1e-07 31.9 0.1 3.8e-05 23.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEG39821.1 - 1.3e-05 24.5 0.3 1.3e-05 24.5 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CEG39821.1 - 0.0011 18.3 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 CEG39821.1 - 0.0012 18.7 0.1 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEG39821.1 - 0.0021 17.4 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CEG39821.1 - 0.0028 17.3 3.2 0.58 9.7 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CEG39821.1 - 0.0029 16.8 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 CEG39821.1 - 0.0079 15.5 0.1 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 CEG39821.1 - 0.091 11.8 1.1 12 4.9 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 CEG39821.1 - 0.1 11.7 1.4 0.18 10.8 0.1 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A XdhC_C PF13478.6 CEG39821.1 - 0.11 13.0 0.0 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain HPS3_N PF14761.6 CEG39822.1 - 1.4e-10 41.1 1.4 3.9e-09 36.4 0.6 3.1 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Fumarate_red_D PF02313.17 CEG39822.1 - 0.047 13.8 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Fumarate reductase subunit D NT-C2 PF10358.9 CEG39823.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins SRC-1 PF08832.10 CEG39823.1 - 1.2 10.2 3.4 2 9.5 0.0 2.6 2 1 0 2 2 2 0 Steroid receptor coactivator RXLR PF16810.5 CEG39825.1 - 0.028 14.9 1.0 0.045 14.2 1.0 1.3 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity NP1-WLL PF11733.8 CEG39825.1 - 0.072 12.9 0.6 0.09 12.5 0.6 1.1 1 0 0 1 1 1 0 Non-capsid protein NP1 DUF1765 PF08578.10 CEG39826.1 - 5.7e-20 72.0 1.5 5.7e-20 72.0 1.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) Dimer_Tnp_hAT PF05699.14 CEG39826.1 - 0.00031 20.5 2.6 0.00059 19.6 0.1 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 CEG39826.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) zf-BED PF02892.15 CEG39826.1 - 1.2 9.2 5.3 0.18 11.8 0.8 2.0 2 0 0 2 2 2 0 BED zinc finger SHE3 PF17078.5 CEG39827.1 - 0.4 10.4 26.5 0.014 15.1 20.6 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 AMP-binding_C_2 PF14535.6 CEG39827.1 - 5.5 7.4 9.7 0.82 10.0 3.1 2.6 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain DivIC PF04977.15 CEG39827.1 - 9.2 6.1 11.4 0.38 10.5 3.9 2.5 2 0 0 2 2 2 0 Septum formation initiator rve PF00665.26 CEG39829.1 - 3.7e-09 36.8 0.0 5.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG39830.1 - 9.5e-10 38.2 0.1 2.5e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.14 CEG39831.1 - 2.2e-62 210.8 0.7 3.5e-62 210.2 0.7 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEG39831.1 - 3.8e-27 94.7 0.4 7.8e-27 93.6 0.4 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 CEG39831.1 - 0.00024 20.8 5.3 0.00062 19.5 5.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEG39831.1 - 0.0015 18.5 3.6 0.0031 17.5 3.6 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 CEG39831.1 - 0.027 14.0 0.1 0.075 12.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3192 PF11399.8 CEG39831.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) zf-C2H2_10 PF16588.5 CEG39831.1 - 0.13 12.0 2.5 0.3 10.8 2.5 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger RVT_2 PF07727.14 CEG39832.1 - 1.1e-72 244.6 0.2 1.3e-72 244.3 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hs1pro-1_C PF07014.12 CEG39832.1 - 0.039 13.4 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus rve PF00665.26 CEG39833.1 - 2e-17 63.5 0.0 2.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG39833.1 - 2.5e-05 24.0 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEG39833.1 - 0.046 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease CLTH PF10607.9 CEG39834.1 - 9e-06 25.6 0.7 1.6e-05 24.8 0.7 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain CALM_bind PF16025.5 CEG39834.1 - 0.8 10.2 4.2 2.7 8.5 4.2 2.0 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding RXLR PF16810.5 CEG39835.1 - 0.057 13.8 2.1 1.1 9.7 0.0 2.7 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity Phosphatase PF15698.5 CEG39837.1 - 0.051 12.7 0.0 0.056 12.6 0.0 1.0 1 0 0 1 1 1 0 Phosphatase RSN1_7TM PF02714.15 CEG39839.1 - 4e-38 131.3 23.2 4e-38 131.3 23.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEG39839.1 - 3.3e-29 101.7 1.9 3.3e-29 101.7 1.9 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEG39839.1 - 1e-26 94.3 0.3 1e-17 65.0 0.0 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Tape_meas_lam_C PF09718.10 CEG39839.1 - 0.12 12.5 0.3 0.44 10.7 0.2 2.0 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ammonium_transp PF00909.21 CEG39841.1 - 1.1e-26 93.5 0.3 1.2e-26 93.4 0.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PGAP1 PF07819.13 CEG39844.1 - 3.6e-05 23.6 0.2 6.6e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CEG39844.1 - 0.091 13.3 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 CEG39845.1 - 0.04 14.5 0.0 0.055 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CEG39845.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein TRAM_LAG1_CLN8 PF03798.16 CEG39846.1 - 1.2e-26 93.6 29.0 1.6e-26 93.3 29.0 1.1 1 0 0 1 1 1 1 TLC domain Kinesin PF00225.23 CEG39848.1 - 1.6e-108 362.6 0.4 5.5e-108 360.8 0.4 2.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG39848.1 - 1e-22 80.7 0.1 6.2e-22 78.1 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding MIP-T3 PF10243.9 CEG39848.1 - 3.3e-10 40.0 0.0 1.4e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain F5_F8_type_C PF00754.25 CEG39848.1 - 0.0051 16.9 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain Pro_isomerase PF00160.21 CEG39850.1 - 9.9e-52 175.4 0.0 1.6e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 CEG39850.1 - 1.9e-29 101.8 0.0 5.5e-29 100.3 0.0 1.8 2 0 0 2 2 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 CEG39850.1 - 4.6e-10 38.8 0.4 0.0012 18.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39850.1 - 7.3e-06 25.8 0.1 0.0025 17.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG39850.1 - 9.1e-06 25.3 0.4 0.0098 15.7 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39850.1 - 0.003 18.2 2.4 0.0067 17.1 0.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG39850.1 - 0.0056 16.6 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39850.1 - 0.012 16.2 0.2 0.52 11.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG39850.1 - 0.013 16.0 1.5 0.21 12.1 0.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEG39850.1 - 0.025 14.9 1.1 0.34 11.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG39850.1 - 0.027 14.5 1.2 0.12 12.5 0.1 2.5 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CEG39850.1 - 0.027 15.2 0.2 0.61 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG39850.1 - 0.073 12.8 0.1 19 5.1 0.0 3.2 3 0 0 3 3 3 0 TPR repeat SRP_TPR_like PF17004.5 CEG39850.1 - 0.095 12.7 0.9 0.17 11.9 0.9 1.3 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_12 PF13424.6 CEG39850.1 - 0.15 12.4 0.1 0.44 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpb1_5 PF04998.17 CEG39851.1 - 2.6e-93 312.3 0.0 4.9e-93 311.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEG39851.1 - 8e-65 218.1 0.2 1.7e-64 217.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEG39851.1 - 1.3e-33 116.2 0.0 7.3e-33 113.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CEG39851.1 - 1.9e-27 96.4 1.9 4e-23 82.2 0.1 3.5 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CEG39851.1 - 3.3e-19 68.8 0.0 9.6e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PhnA_Zn_Ribbon PF08274.12 CEG39851.1 - 0.82 9.7 2.6 18 5.4 0.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Beta_elim_lyase PF01212.21 CEG39855.1 - 0.00011 21.6 0.1 0.00013 21.3 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1256 PF06866.11 CEG39855.1 - 0.047 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) DUF4783 PF16022.5 CEG39857.1 - 0.052 13.7 0.0 0.06 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) CS PF04969.16 CEG39858.1 - 0.0017 19.3 0.6 0.0043 18.0 0.6 1.6 2 0 0 2 2 2 1 CS domain SecE PF00584.20 CEG39858.1 - 0.0056 16.6 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex zf-HIT PF04438.16 CEG39859.1 - 3.6e-05 23.5 13.1 0.00013 21.7 13.1 1.9 1 0 0 1 1 1 1 HIT zinc finger WD40 PF00400.32 CEG39859.1 - 0.00026 21.7 1.0 0.5 11.3 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PolC_DP2 PF03833.13 CEG39859.1 - 0.013 13.4 4.6 0.02 12.8 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF5046 PF16465.5 CEG39859.1 - 0.064 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) TPR_1 PF00515.28 CEG39860.1 - 0.00032 20.4 9.6 0.18 11.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG39860.1 - 0.00079 19.4 7.3 0.15 12.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG39860.1 - 0.06 13.6 4.5 3.2 8.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Chromo_shadow PF01393.19 CEG39860.1 - 0.08 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain TPR_11 PF13414.6 CEG39860.1 - 0.25 11.0 4.7 0.48 10.1 0.1 3.3 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 CEG39860.1 - 0.62 10.6 5.9 2.7 8.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG39860.1 - 3 8.9 4.9 29 5.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat LSM PF01423.22 CEG39861.1 - 0.00011 21.8 0.2 0.35 10.6 0.1 2.1 1 1 1 2 2 2 2 LSM domain PNISR PF15996.5 CEG39863.1 - 0.23 11.7 5.3 0.23 11.7 0.5 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF4050 PF13259.6 CEG39863.1 - 0.52 10.6 6.2 0.68 10.2 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) TNF PF00229.18 CEG39864.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family SUA5 PF03481.13 CEG39865.1 - 0.089 13.4 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding MAGUK_N_PEST PF10608.9 CEG39865.1 - 0.12 12.8 1.1 0.22 12.0 1.1 1.4 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK ERAP1_C PF11838.8 CEG39868.1 - 7.2e-69 232.7 0.1 8.2e-69 232.5 0.1 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FYVE PF01363.21 CEG39872.1 - 0.5 10.6 9.5 1.2 9.4 9.2 1.8 1 1 1 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 CEG39872.1 - 9.5 6.5 9.3 3.5 7.9 6.5 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger PK PF00224.21 CEG39874.1 - 8.3e-134 445.9 1.0 1.3e-133 445.3 1.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CEG39874.1 - 3e-25 88.7 0.2 5e-24 84.8 0.1 2.6 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain FYVE_2 PF02318.16 CEG39874.1 - 0.38 11.0 3.7 0.84 9.9 3.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger YmzC PF14157.6 CEG39875.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 YmzC-like protein zf-Sec23_Sec24 PF04810.15 CEG39876.1 - 0.019 15.0 0.4 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF3382 PF11862.8 CEG39880.1 - 0.0091 16.2 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3382) RVT_2 PF07727.14 CEG39881.1 - 1.1e-39 136.5 0.0 1.5e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 CEG39881.1 - 0.0042 16.8 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Chlororespiratory reduction 6 RVT_2 PF07727.14 CEG39882.1 - 4.8e-35 121.4 0.1 6.7e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEG39882.1 - 3.2e-21 75.7 0.0 7.5e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEG39882.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CEG39882.1 - 0.00034 20.3 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_3 PF13456.6 CEG39882.1 - 0.0028 17.5 0.8 0.1 12.4 0.1 2.6 2 0 0 2 2 2 1 Reverse transcriptase-like Methyltransf_16 PF10294.9 CEG39883.1 - 2.3e-23 82.8 0.0 6.4e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEG39883.1 - 4.6e-06 26.3 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG39883.1 - 0.013 16.2 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEG39883.1 - 0.019 15.7 0.0 0.029 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CTP_transf_like PF01467.26 CEG39884.1 - 3.2e-11 43.6 0.0 4.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Tyr_Deacylase PF02580.16 CEG39885.1 - 2.4e-49 167.6 0.0 2.7e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Mis12 PF05859.12 CEG39887.1 - 4.6e-14 52.6 3.6 4.6e-14 52.6 3.6 1.7 2 0 0 2 2 2 1 Mis12 protein DUF4952 PF16310.5 CEG39887.1 - 0.044 14.0 0.2 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Domian of unknown function (DUF4952) tRNA-synt_1c PF00749.21 CEG39887.1 - 0.07 12.0 4.7 0.58 9.0 0.1 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF948 PF06103.11 CEG39887.1 - 1.3 9.3 4.1 1.7 9.0 0.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1451 PF07295.11 CEG39887.1 - 2.9 7.9 11.3 0.86 9.6 1.6 3.0 1 1 2 3 3 3 0 Zinc-ribbon containing domain UPF0449 PF15136.6 CEG39887.1 - 8.5 6.9 13.9 2.5 8.6 9.1 2.7 2 2 1 3 3 3 0 Uncharacterised protein family UPF0449 NADH_B2 PF14813.6 CEG39888.1 - 0.0017 18.1 3.2 0.0049 16.6 3.0 1.8 1 1 1 2 2 2 1 NADH dehydrogenase 1 beta subcomplex subunit 2 p25-alpha PF05517.12 CEG39891.1 - 8e-06 26.1 0.0 0.0026 18.0 0.0 2.6 2 0 0 2 2 2 2 p25-alpha DUF3216 PF11505.8 CEG39891.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) DUF5476 PF17570.2 CEG39891.1 - 0.15 12.5 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5476) THF_DHG_CYH_C PF02882.19 CEG39892.1 - 3.3e-61 205.3 0.1 5.2e-61 204.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CEG39892.1 - 5.9e-32 110.4 0.0 8.4e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Hexapep PF00132.24 CEG39893.1 - 3.8e-10 39.1 10.7 1.2e-06 27.9 1.8 3.8 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEG39893.1 - 3.3e-08 33.1 8.8 0.0001 22.0 1.5 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CEG39893.1 - 0.017 14.1 0.9 1.2 8.0 0.1 2.0 1 1 1 2 2 2 0 L-fucokinase MRC1 PF09444.10 CEG39894.1 - 7.2e-09 36.3 14.4 7.2e-09 36.3 14.4 5.6 4 2 0 5 5 5 1 MRC1-like domain C2 PF00168.30 CEG39895.1 - 0.0068 16.7 0.0 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain FYVE PF01363.21 CEG39896.1 - 5.3e-11 42.5 9.2 1.1e-10 41.4 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 CEG39897.1 - 6.9e-20 71.3 0.0 9.4e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain Auxin_inducible PF02519.14 CEG39898.1 - 0.059 13.5 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Auxin responsive protein TRAM_LAG1_CLN8 PF03798.16 CEG39899.1 - 3.7e-28 98.6 21.2 4.8e-28 98.3 21.2 1.1 1 0 0 1 1 1 1 TLC domain DAHP_synth_1 PF00793.20 CEG39903.1 - 1.3e-98 329.3 0.0 1.6e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DDHD PF02862.17 CEG39906.1 - 9.7e-43 146.9 0.1 2.9e-42 145.3 0.0 1.9 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 CEG39906.1 - 0.018 15.6 0.7 4.6 7.9 0.0 3.0 2 0 0 2 2 2 0 WWE domain HBM PF16591.5 CEG39906.1 - 0.052 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF676 PF05057.14 CEG39906.1 - 0.074 12.6 0.1 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Csc2 PF18320.1 CEG39907.1 - 0.072 12.0 0.1 0.17 10.8 0.0 1.7 1 1 0 1 1 1 0 Csc2 Crispr Lipoprotein_6 PF01441.19 CEG39909.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein CBM_1 PF00734.18 CEG39910.1 - 0.11 12.5 0.7 0.15 12.1 0.7 1.2 1 0 0 1 1 1 0 Fungal cellulose binding domain Aldedh PF00171.22 CEG39912.1 - 3.2e-183 609.5 0.1 3.7e-183 609.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_4 PF13562.6 CEG39912.1 - 0.045 14.0 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Skp1 PF01466.19 CEG39913.1 - 7.3e-28 96.4 0.4 7.3e-28 96.4 0.4 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CEG39913.1 - 7.3e-22 77.3 0.4 1.4e-21 76.4 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 CEG39913.1 - 0.00011 22.3 0.2 0.00081 19.6 0.2 2.0 1 1 0 1 1 1 1 BTB/POZ domain Anoctamin PF04547.12 CEG39914.1 - 6.8e-119 397.6 5.1 9.4e-119 397.2 5.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CEG39914.1 - 0.036 13.8 0.1 1.8 8.2 0.0 2.5 1 1 1 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin BT1 PF03092.16 CEG39915.1 - 8.8e-33 113.3 11.5 2.3e-20 72.3 1.1 2.1 2 0 0 2 2 2 2 BT1 family DegT_DnrJ_EryC1 PF01041.17 CEG39916.1 - 1.2e-28 100.4 0.0 1.3e-24 87.2 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEG39916.1 - 3.1e-07 29.7 0.0 5.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEG39916.1 - 1.4e-05 24.4 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_72 PF03198.14 CEG39917.1 - 4.2e-43 147.8 4.7 1.9e-37 129.2 3.7 2.3 1 1 1 2 2 2 2 Glucanosyltransferase Cellulase PF00150.18 CEG39917.1 - 0.00097 18.6 0.1 0.0044 16.5 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) VASt PF16016.5 CEG39919.1 - 1e-51 175.4 0.0 1.8e-24 86.9 0.0 2.3 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain Pex24p PF06398.11 CEG39919.1 - 6.8e-14 51.6 1.6 6.8e-14 51.6 1.6 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin PH PF00169.29 CEG39919.1 - 4.4e-07 30.4 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG39919.1 - 0.0092 16.2 0.0 0.092 13.0 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PK PF00224.21 CEG39926.1 - 1.4e-145 484.6 0.3 2.7e-145 483.6 0.1 1.5 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CEG39926.1 - 8e-28 97.0 0.5 2e-27 95.7 0.5 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEG39926.1 - 5.1e-05 22.5 0.2 0.00015 21.0 0.1 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family TniB PF05621.11 CEG39926.1 - 0.18 11.2 0.1 0.35 10.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PHF5 PF03660.14 CEG39927.1 - 3.5e-50 168.6 11.2 3.9e-50 168.4 11.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CEG39927.1 - 0.046 11.6 5.8 0.051 11.4 5.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CEG39927.1 - 5 7.2 13.3 3.6 7.7 1.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon RVT_2 PF07727.14 CEG39928.1 - 6.8e-18 65.2 1.1 1.1e-17 64.5 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEG39929.1 - 1.7e-20 73.1 0.4 2.5e-20 72.6 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG39929.1 - 4.3e-05 23.4 4.5 7.6e-05 22.6 4.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEG39929.1 - 0.016 14.9 1.6 0.034 13.9 1.6 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 CEG39929.1 - 2.5 8.2 5.9 0.3 11.1 1.7 1.7 2 0 0 2 2 2 0 Zinc knuckle MS_channel PF00924.18 CEG39931.1 - 1.3e-11 44.5 3.4 2.2e-11 43.7 3.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Vasohibin PF14822.6 CEG39933.1 - 7.8e-63 212.0 0.0 1.1e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Vasohibin Tim17 PF02466.19 CEG39934.1 - 2.5e-17 63.3 4.3 5.2e-17 62.2 4.3 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.24 CEG39934.1 - 0.00027 20.9 0.2 0.00063 19.7 0.2 1.5 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 CEG39935.1 - 0.044 13.1 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain THEG4 PF15834.5 CEG39936.1 - 0.026 14.5 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 FYVE PF01363.21 CEG39939.1 - 0.032 14.4 7.1 0.062 13.4 7.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Endonuclease_7 PF02945.15 CEG39939.1 - 0.036 14.0 4.1 0.09 12.7 4.1 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII TGF_beta_GS PF08515.12 CEG39942.1 - 0.12 11.9 0.6 0.12 11.9 0.6 1.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Acyl_transf_3 PF01757.22 CEG39943.1 - 1.9e-09 37.1 45.6 3.1e-09 36.4 45.5 1.4 1 1 0 1 1 1 1 Acyltransferase family Ax_dynein_light PF10211.9 CEG39944.1 - 4.7e-83 277.7 10.2 6.1e-83 277.4 10.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ubiquitin PF00240.23 CEG39944.1 - 0.00014 21.5 0.8 0.0014 18.3 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin family PRKG1_interact PF15898.5 CEG39944.1 - 0.11 13.4 8.5 0.26 12.2 8.5 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain KLRAQ PF10205.9 CEG39944.1 - 0.11 12.8 7.6 2.8 8.2 2.4 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 CEG39944.1 - 0.17 12.3 2.4 13 6.3 0.0 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Asn_synthase PF00733.21 CEG39945.1 - 1.9e-17 64.0 0.7 2.3e-08 34.1 0.2 2.7 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CEG39945.1 - 4e-09 36.4 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEG39945.1 - 2.6e-06 27.6 0.0 6.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEG39945.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein zf-A20 PF01754.16 CEG39950.1 - 1.9e-09 37.3 5.3 5.1e-09 35.9 5.3 1.8 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 CEG39950.1 - 2.2e-09 37.3 8.5 2.2e-09 37.3 8.5 1.6 2 0 0 2 2 2 1 AN1-like Zinc finger UPF0547 PF10571.9 CEG39950.1 - 0.0057 16.7 3.4 0.0057 16.7 3.4 2.4 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 Vps39_2 PF10367.9 CEG39950.1 - 0.2 12.1 3.9 0.74 10.3 0.9 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.6 CEG39950.1 - 2.8 7.8 12.0 23 4.9 0.0 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain IBR PF01485.21 CEG39951.1 - 0.87 9.9 7.5 0.11 12.8 2.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CEG39951.1 - 1.4 9.1 11.6 0.081 13.1 5.9 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger DUF1275 PF06912.11 CEG39952.1 - 1 9.3 11.0 1.8 8.4 1.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1275) FYVE_2 PF02318.16 CEG39953.1 - 0.005 17.1 4.8 0.014 15.6 4.8 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger Pkinase_Tyr PF07714.17 CEG39954.1 - 4.4e-69 232.6 0.0 6e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG39954.1 - 7.7e-59 199.2 0.0 1.1e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEG39954.1 - 0.00078 18.8 0.0 0.0018 17.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEG39954.1 - 0.0015 17.6 0.1 0.0032 16.5 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG39954.1 - 0.0069 15.2 0.6 0.032 13.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase GTP_EFTU PF00009.27 CEG39955.1 - 3.2e-58 196.5 0.1 4.2e-58 196.1 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEG39955.1 - 9.6e-31 106.4 0.0 2.1e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEG39955.1 - 2.9e-16 59.6 1.8 2.9e-16 59.6 1.8 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG39955.1 - 7.2e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CEG39955.1 - 0.044 13.4 0.3 0.096 12.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rac1 PF09632.10 CEG39955.1 - 0.23 10.6 0.0 0.45 9.6 0.0 1.4 1 0 0 1 1 1 0 Rac1-binding domain SLT_beta PF02258.16 CEG39956.1 - 0.02 14.9 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Shiga-like toxin beta subunit PWI PF01480.17 CEG39957.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 PWI domain Glutaredoxin PF00462.24 CEG39958.1 - 1.1e-18 67.1 0.0 1.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CEG39958.1 - 0.00012 22.4 0.0 0.00015 22.1 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 CEG39958.1 - 0.00071 19.5 0.0 0.00086 19.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CEG39958.1 - 0.0024 18.3 0.1 0.0057 17.1 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 CEG39958.1 - 0.0063 16.3 0.4 0.086 12.6 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N_2 PF13409.6 CEG39958.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEG39958.1 - 0.021 15.2 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF5033 PF16436.5 CEG39959.1 - 0.022 14.7 0.0 0.023 14.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) GerD PF17898.1 CEG39961.1 - 0.38 10.7 8.3 0.068 13.1 1.0 3.1 3 1 0 3 3 3 0 Spore germination GerD central core domain RPAP3_C PF13877.6 CEG39961.1 - 1 9.9 6.1 2.2 8.9 0.2 4.0 4 1 1 5 5 5 0 Potential Monad-binding region of RPAP3 Enterotoxin_ST PF02048.16 CEG39963.1 - 6.1 7.4 9.7 9.7 6.8 0.7 3.9 2 0 0 2 2 2 0 Heat-stable enterotoxin ST Sacchrp_dh_NADP PF03435.18 CEG39964.1 - 1.5e-13 51.2 0.0 2.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 CEG39964.1 - 0.027 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family MMR_HSR1 PF01926.23 CEG39965.1 - 6.4e-17 61.7 0.3 8.2e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG39965.1 - 5.7e-08 32.4 0.3 1.6e-05 24.5 0.0 2.7 2 1 1 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG39965.1 - 1.3e-06 28.4 0.6 0.072 13.0 0.0 2.7 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG39965.1 - 0.00026 20.6 0.7 0.011 15.3 0.1 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain UPF0767 PF15990.5 CEG39965.1 - 0.053 13.7 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 UPF0767 family AAA_16 PF13191.6 CEG39965.1 - 0.071 13.5 0.5 0.79 10.1 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 CEG39965.1 - 0.16 12.5 0.5 0.63 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CEG39965.1 - 0.92 9.5 6.4 0.57 10.2 0.5 3.0 2 2 1 3 3 3 0 Dynamin family PX PF00787.24 CEG39967.1 - 1.1e-10 41.5 0.2 2.2e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 PX domain RNA_pol_Rpc4 PF05132.14 CEG39969.1 - 4.5e-18 66.1 0.6 6.8e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase III RPC4 API5 PF05918.11 CEG39969.1 - 0.043 12.6 8.1 0.058 12.2 8.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Myb_DNA-binding PF00249.31 CEG39970.1 - 1.9e-39 133.6 11.2 1e-12 48.0 1.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG39970.1 - 2.7e-32 110.8 4.0 1e-14 54.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 CEG39970.1 - 0.0089 16.3 6.9 2.6 8.4 0.1 3.4 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CEG39970.1 - 0.063 13.7 3.0 6.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CEG39970.1 - 0.08 13.1 0.7 8.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 CEG39970.1 - 0.17 11.8 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.8 CEG39970.1 - 0.17 12.0 5.7 13 5.9 0.4 3.4 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 CEG39970.1 - 0.17 11.9 0.0 37 4.4 0.0 2.9 3 1 0 3 3 3 0 SLIDE Aldolase_II PF00596.21 CEG39971.1 - 2.1e-38 132.1 0.0 3.6e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 CEG39971.1 - 7.3e-08 32.9 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEG39971.1 - 5.5e-05 23.3 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase IFT57 PF10498.9 CEG39972.1 - 1.1e-103 347.0 0.0 1.3e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 BicD PF09730.9 CEG39972.1 - 0.015 13.7 0.9 0.023 13.1 0.9 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D KELK PF15796.5 CEG39972.1 - 0.031 14.7 1.8 0.066 13.7 0.8 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 CEG39972.1 - 0.06 13.4 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HTH_Tnp_1 PF01527.20 CEG39973.1 - 0.0025 18.1 0.2 0.041 14.2 0.0 2.8 2 1 1 3 3 3 1 Transposase HTH_28 PF13518.6 CEG39973.1 - 0.023 14.8 0.0 0.75 10.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 CEG39973.1 - 0.064 13.1 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Terminase_5 PF06056.12 CEG39973.1 - 0.1 12.5 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 CEG39973.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Ion_trans PF00520.31 CEG39974.1 - 5.1e-142 471.3 83.5 2.4e-43 148.2 14.4 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CEG39974.1 - 5.5e-07 28.6 64.1 4.6e-05 22.3 11.7 7.4 6 3 0 7 7 7 5 Polycystin cation channel S1 PF00575.23 CEG39975.1 - 2.6e-48 162.3 24.2 1.3e-10 41.5 0.4 12.4 12 0 0 12 12 12 7 S1 RNA binding domain TPR_19 PF14559.6 CEG39975.1 - 2.8e-08 34.2 3.7 0.29 11.7 0.0 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat Suf PF05843.14 CEG39975.1 - 1.5e-06 28.5 1.6 1.5e-06 28.5 1.6 3.7 2 1 4 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEG39975.1 - 1.9e-05 25.1 2.7 0.97 10.4 0.0 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG39975.1 - 0.0032 18.0 0.1 0.057 14.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG39975.1 - 0.05 14.3 0.0 0.05 14.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 CEG39976.1 - 0.011 16.1 0.0 0.096 13.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEG39976.1 - 0.026 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG39976.1 - 0.096 13.1 0.1 0.76 10.1 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 CEG39976.1 - 0.12 12.2 0.1 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Bacteriocin_II PF01721.18 CEG39976.1 - 0.2 11.8 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Class II bacteriocin Trypsin_2 PF13365.6 CEG39979.1 - 1.3e-13 52.1 0.0 3.4e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG39979.1 - 0.031 14.1 2.0 0.33 10.7 2.0 2.4 1 1 0 1 1 1 0 Trypsin Peptidase_C4 PF00863.19 CEG39979.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C4 ANAPC10 PF03256.16 CEG39981.1 - 8e-65 217.9 0.1 8.8e-65 217.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CEG39981.1 - 0.0037 17.4 0.1 0.007 16.5 0.1 1.5 2 0 0 2 2 2 1 F5/8 type C domain PITH PF06201.13 CEG39981.1 - 0.15 12.3 0.1 1.1 9.4 0.1 1.9 1 1 1 2 2 2 0 PITH domain DASH_Dad1 PF08649.10 CEG39982.1 - 0.0083 16.3 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 RIO1 PF01163.22 CEG39983.1 - 1e-75 253.5 0.2 1e-75 253.5 0.2 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CEG39983.1 - 5.2e-05 22.2 0.0 5.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG39983.1 - 0.041 13.8 0.0 3.1 7.6 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.14 CEG39983.1 - 0.16 10.2 10.5 0.22 9.8 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 CEG39983.1 - 0.72 9.9 22.3 1.4 9.0 22.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein ELO PF01151.18 CEG39984.1 - 1.1e-47 162.7 24.1 1.3e-47 162.5 24.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 CEG39984.1 - 0.26 11.5 2.0 4.1 7.6 0.1 2.5 1 1 1 2 2 2 0 CCSMST1 family FlaC_arch PF05377.11 CEG39985.1 - 0.011 16.1 4.1 0.03 14.7 4.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) WD40 PF00400.32 CEG39985.1 - 0.012 16.5 11.4 9.7 7.3 0.2 5.6 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF16 PF01519.16 CEG39985.1 - 0.021 15.3 0.6 0.044 14.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Med14 PF08638.11 CEG39985.1 - 0.032 13.7 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit MED14 NleF_casp_inhib PF16809.5 CEG39985.1 - 0.036 14.0 0.9 0.078 12.9 0.9 1.5 1 0 0 1 1 1 0 NleF caspase inhibitor DUF4349 PF14257.6 CEG39985.1 - 0.14 11.6 1.1 0.28 10.6 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PD40 PF07676.12 CEG39985.1 - 0.15 12.0 1.9 0.27 11.2 0.0 2.5 3 0 0 3 3 2 0 WD40-like Beta Propeller Repeat Prefoldin PF02996.17 CEG39985.1 - 0.32 10.9 3.3 0.58 10.1 3.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.15 CEG39985.1 - 1 9.2 5.2 2.6 7.9 5.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 CEG39985.1 - 3.1 8.1 8.7 0.13 12.5 1.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CEG39985.1 - 5.5 7.5 12.1 3 8.4 9.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2062 PF09835.9 CEG39987.1 - 0.016 15.1 0.4 0.028 14.3 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) LMBR1 PF04791.16 CEG39987.1 - 0.077 11.9 10.5 0.11 11.4 10.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cystatin PF00031.21 CEG39988.1 - 0.0084 16.4 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CEG39988.1 - 0.016 15.6 0.1 0.065 13.6 0.1 2.0 1 1 0 1 1 1 0 Aspartic acid proteinase inhibitor RRM_1 PF00076.22 CEG39989.1 - 1.3e-12 47.3 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gal-bind_lectin PF00337.22 CEG39989.1 - 1.4e-11 44.1 0.0 2.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin Fic_N PF13784.6 CEG39989.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Fic/DOC family N-terminal SHS2_Rpb7-N PF03876.17 CEG39990.1 - 1.6e-13 50.8 0.3 8e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CEG39990.1 - 4.8e-11 42.8 0.1 1.2e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain UPF0172 PF03665.13 CEG39993.1 - 2.1e-48 164.9 0.1 2.4e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 CEG39993.1 - 3e-05 24.0 0.0 6.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JmjC PF02373.22 CEG39994.1 - 2.1e-19 70.0 0.0 4.6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CEG39994.1 - 2.5e-19 70.0 0.1 1.1e-18 67.8 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain Nucleoporin_FG PF13634.6 CEG39997.1 - 1.7 9.6 8.9 4.2 8.3 8.4 1.9 1 1 1 2 2 2 0 Nucleoporin FG repeat region Nup_retrotrp_bd PF10599.9 CEG39997.1 - 8.1 7.2 9.7 18 6.1 9.5 1.7 1 1 0 1 1 1 0 Retro-transposon transporting motif Pkinase PF00069.25 CEG40000.1 - 1.4e-17 64.0 0.0 2.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain HEAT PF02985.22 CEG40000.1 - 8.2e-15 53.6 5.4 0.098 13.0 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat WD40 PF00400.32 CEG40000.1 - 2e-11 44.2 8.2 0.0014 19.4 0.0 6.9 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 CEG40000.1 - 1.3e-08 35.1 0.1 0.0064 16.9 0.0 4.9 3 2 3 6 6 6 3 HEAT repeats Pkinase_Tyr PF07714.17 CEG40000.1 - 2.1e-05 24.0 0.0 0.00031 20.1 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase HEAT_EZ PF13513.6 CEG40000.1 - 0.00021 21.7 0.1 0.13 12.8 0.0 3.9 3 0 0 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 CEG40000.1 - 0.0013 18.3 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Tti2 family Nup160 PF11715.8 CEG40000.1 - 0.0022 16.7 1.8 0.17 10.5 0.2 3.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEG40000.1 - 0.0035 17.6 1.4 11 6.4 0.1 4.1 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4042 PF13251.6 CEG40000.1 - 0.03 14.1 0.5 7 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) Adaptin_N PF01602.20 CEG40000.1 - 0.064 11.8 0.1 0.58 8.7 0.1 2.1 1 1 1 2 2 2 0 Adaptin N terminal region APH PF01636.23 CEG40000.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nop25 PF09805.9 CEG40001.1 - 4.8e-16 59.5 12.5 4.8e-16 59.5 12.5 2.3 1 1 1 2 2 2 2 Nucleolar protein 12 (25kDa) GBP PF02263.19 CEG40002.1 - 4e-66 222.9 0.0 7.2e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CEG40002.1 - 1.4e-12 47.6 16.7 1.9e-10 40.6 0.1 2.8 2 1 0 2 2 2 2 Guanylate-binding protein, C-terminal domain PH PF00169.29 CEG40002.1 - 4.5e-08 33.5 0.0 8.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_2 PF09068.11 CEG40002.1 - 0.02 15.1 0.8 0.096 12.8 0.1 2.5 3 0 0 3 3 3 0 EF hand DUF3662 PF12401.8 CEG40002.1 - 0.053 13.9 1.8 8.2 6.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2662) MMR_HSR1 PF01926.23 CEG40002.1 - 0.053 13.6 0.1 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase PH_11 PF15413.6 CEG40002.1 - 0.057 13.9 3.4 0.096 13.1 0.2 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain SRP54_N PF02881.19 CEG40002.1 - 0.12 12.6 0.4 0.4 10.9 0.4 2.0 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF455 PF04305.14 CEG40006.1 - 6.2e-78 261.8 0.0 9.2e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Glyco_trans_1_4 PF13692.6 CEG40006.1 - 1.1e-13 51.8 0.0 2.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ferritin PF00210.24 CEG40006.1 - 0.096 12.6 0.1 0.38 10.7 0.1 1.9 1 1 1 2 2 2 0 Ferritin-like domain RabGAP-TBC PF00566.18 CEG40007.1 - 9.5e-38 130.0 1.7 1.5e-37 129.4 1.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain fn3 PF00041.21 CEG40007.1 - 7.5e-13 48.6 3.2 9.5e-08 32.3 0.5 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG40007.1 - 2e-07 31.5 5.4 0.0022 18.5 0.7 3.6 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain PDZ PF00595.24 CEG40007.1 - 7.1e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG40007.1 - 0.00014 21.6 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Rhodanese PF00581.20 CEG40007.1 - 0.00074 20.0 0.0 0.2 12.2 0.0 2.7 2 0 0 2 2 2 1 Rhodanese-like domain PDZ_2 PF13180.6 CEG40007.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Cytotoxic PF09000.10 CEG40010.1 - 0.029 14.7 0.1 0.89 9.9 0.0 2.0 1 1 1 2 2 2 0 Cytotoxic F-box-like PF12937.7 CEG40011.1 - 0.00069 19.5 1.1 0.0032 17.3 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEG40011.1 - 0.095 12.6 1.4 0.36 10.7 0.3 2.6 3 0 0 3 3 3 0 F-box domain FYVE PF01363.21 CEG40014.1 - 3.1e-06 27.2 9.4 3.1e-06 27.2 9.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger WRNPLPNID PF15017.6 CEG40015.1 - 0.1 13.5 0.0 0.13 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box FYVE PF01363.21 CEG40016.1 - 1.6e-06 28.1 14.7 1.6e-06 28.1 14.7 1.6 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 CEG40016.1 - 0.079 13.2 7.3 0.16 12.2 7.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger TPD PF14811.6 CEG40017.1 - 1.2e-29 102.9 0.0 2.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif HTH_18 PF12833.7 CEG40017.1 - 0.11 12.8 0.0 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain PX PF00787.24 CEG40018.1 - 0.00048 20.1 2.2 0.0011 18.9 1.6 2.0 1 1 0 1 1 1 1 PX domain C1_4 PF07975.12 CEG40018.1 - 0.055 13.7 0.5 0.13 12.5 0.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Trypsin_2 PF13365.6 CEG40020.1 - 2.5e-25 90.1 3.7 1.1e-19 71.8 0.2 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_1 PF12812.7 CEG40020.1 - 4.9e-22 77.7 0.0 2.9e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.6 CEG40020.1 - 1.9e-18 66.5 3.2 5e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CEG40020.1 - 7.7e-14 51.3 2.3 8.6e-05 22.3 0.1 5.1 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 CEG40020.1 - 4.1e-09 36.7 0.0 0.0002 21.6 0.0 4.1 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 CEG40020.1 - 2.2e-05 24.3 1.1 0.15 12.1 0.1 4.2 4 0 0 4 4 4 2 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 CEG40020.1 - 0.00091 18.0 0.3 0.00091 18.0 0.3 1.7 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 CEG40020.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin UreE_N PF02814.15 CEG40020.1 - 0.044 13.4 0.2 2.2 7.9 0.2 2.7 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Peptidase_S7 PF00949.21 CEG40020.1 - 0.13 12.1 0.5 0.32 10.8 0.5 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 CEG40020.1 - 0.14 11.7 0.5 0.27 10.7 0.5 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) TPR_2 PF07719.17 CEG40021.1 - 4.4e-10 38.9 48.5 0.034 14.3 0.1 16.0 17 0 0 17 17 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40021.1 - 1.3e-08 34.3 21.2 0.14 12.4 0.0 11.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40021.1 - 8.3e-08 32.1 19.2 11 6.7 0.0 11.7 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40021.1 - 7.6e-07 29.7 29.4 0.0027 18.3 0.1 10.4 12 1 0 12 12 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40021.1 - 6e-05 22.7 41.7 0.014 15.2 0.0 13.1 15 0 0 15 15 15 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40021.1 - 0.0016 18.7 17.5 0.012 15.8 1.1 7.3 8 0 0 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CEG40021.1 - 0.0019 17.2 0.1 0.0072 15.3 0.0 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 CEG40021.1 - 0.0029 17.5 8.7 0.048 13.7 0.1 6.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG40021.1 - 0.006 16.8 34.2 0.22 11.8 0.1 11.4 12 1 1 13 13 13 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40021.1 - 0.027 14.2 21.7 0.33 10.7 0.0 8.6 11 1 1 12 12 12 0 TPR repeat TPR_5 PF12688.7 CEG40021.1 - 0.027 14.7 0.2 0.26 11.6 0.1 2.9 2 0 0 2 2 1 0 Tetratrico peptide repeat TPR_14 PF13428.6 CEG40021.1 - 0.049 14.5 36.9 14 6.9 0.2 12.1 11 3 3 14 14 12 0 Tetratricopeptide repeat SMBP PF16785.5 CEG40021.1 - 0.062 13.5 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Small metal-binding protein TPR_4 PF07721.14 CEG40021.1 - 0.13 13.0 14.9 0.16 12.7 0.1 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40021.1 - 2.3 8.4 18.7 0.46 10.7 1.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40021.1 - 3.5 8.2 38.4 0.12 12.9 0.9 10.1 11 1 2 13 13 13 0 Tetratricopeptide repeat Ribonuc_P_40 PF08584.11 CEG40022.1 - 3.4e-74 249.7 0.0 4e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ParE_toxin PF05016.15 CEG40024.1 - 0.0021 18.6 0.2 1.2 9.7 0.0 2.6 2 1 0 2 2 2 2 ParE toxin of type II toxin-antitoxin system, parDE RecG_N PF17190.4 CEG40024.1 - 0.12 13.1 0.2 0.44 11.3 0.0 2.0 2 0 0 2 2 2 0 RecG N-terminal helical domain Retrotrans_gag PF03732.17 CEG40026.1 - 0.00079 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein UBA2_C PF16195.5 CEG40027.1 - 0.043 14.5 0.0 0.055 14.2 0.0 1.1 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus TP_methylase PF00590.20 CEG40028.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MGC-24 PF05283.11 CEG40029.1 - 1 9.8 8.4 1.5 9.2 8.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MSA-2c PF12238.8 CEG40029.1 - 5.7 6.9 7.6 8.2 6.4 7.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Alpha_GJ PF03229.13 CEG40029.1 - 7.3 7.2 11.0 14 6.2 11.0 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J Retrotrans_gag PF03732.17 CEG40030.1 - 1.4e-07 31.7 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Antimicrobial_1 PF08018.11 CEG40030.1 - 0.025 14.7 0.3 0.059 13.5 0.3 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide TIP39 PF14980.6 CEG40030.1 - 0.031 14.2 0.3 0.072 13.0 0.3 1.7 1 0 0 1 1 1 0 TIP39 peptide DUF4939 PF16297.5 CEG40030.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) SKN1 PF03935.15 CEG40031.1 - 1.9e-53 181.6 18.1 4.3e-36 124.4 9.5 4.4 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 CEG40031.1 - 0.1 12.9 4.1 0.071 13.4 1.3 2.2 2 0 0 2 2 2 0 EB module Toxin_2 PF00451.19 CEG40031.1 - 2.2 8.7 10.3 14 6.1 10.3 2.3 1 1 0 1 1 1 0 Scorpion short toxin, BmKK2 ELMO_CED12 PF04727.13 CEG40032.1 - 2.8e-34 118.8 0.0 4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-RanBP PF00641.18 CEG40032.1 - 3e-05 23.2 2.3 7.4e-05 22.0 2.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UBM PF14377.6 CEG40032.1 - 0.0051 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin binding region partial_CstF PF15861.5 CEG40033.1 - 0.027 14.2 0.4 0.031 14.1 0.4 1.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain T4SS PF07996.11 CEG40034.1 - 0.0016 18.9 2.7 0.002 18.6 0.4 2.2 2 0 0 2 2 2 1 Type IV secretion system proteins DUF724 PF05266.14 CEG40034.1 - 0.027 14.3 1.1 0.027 14.3 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.12 CEG40034.1 - 0.034 14.7 3.2 3.3 8.4 0.4 3.7 2 0 0 2 2 2 0 SlyX XhlA PF10779.9 CEG40034.1 - 0.038 14.2 1.4 0.038 14.2 1.4 2.3 2 0 0 2 2 1 0 Haemolysin XhlA KLRAQ PF10205.9 CEG40034.1 - 0.097 12.9 0.3 0.097 12.9 0.3 3.9 5 1 0 5 5 3 0 Predicted coiled-coil domain-containing protein PspA_IM30 PF04012.12 CEG40034.1 - 0.36 10.4 13.4 0.58 9.7 2.1 2.5 2 0 0 2 2 2 0 PspA/IM30 family PI3K_P85_iSH2 PF16454.5 CEG40034.1 - 0.65 9.6 16.6 0.45 10.1 8.4 3.5 2 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 CEG40034.1 - 0.67 9.9 7.3 0.087 12.7 1.3 2.8 3 1 0 3 3 3 0 Prefoldin subunit Taxilin PF09728.9 CEG40034.1 - 0.83 8.8 22.0 0.44 9.7 10.5 2.6 2 0 0 2 2 2 0 Myosin-like coiled-coil protein CC2-LZ PF16516.5 CEG40034.1 - 0.89 10.0 14.7 0.19 12.1 1.8 3.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Tropomyosin PF00261.20 CEG40034.1 - 2.2 7.6 13.8 0.14 11.5 1.4 2.9 3 1 0 3 3 3 0 Tropomyosin DUF2721 PF11026.8 CEG40034.1 - 2.9 7.8 4.8 5.6 6.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2968 PF11180.8 CEG40034.1 - 3 7.4 10.1 0.55 9.8 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) CHASE3 PF05227.13 CEG40034.1 - 5.5 6.9 7.5 2.3 8.1 2.6 2.6 2 0 0 2 2 2 0 CHASE3 domain DUF16 PF01519.16 CEG40034.1 - 8 7.0 14.8 2.6 8.6 0.3 4.4 3 2 0 3 3 3 0 Protein of unknown function DUF16 Peptidase_C7 PF01830.18 CEG40035.1 - 0.11 11.8 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase C7 family BenE PF03594.13 CEG40035.1 - 0.18 10.6 0.2 0.24 10.1 0.2 1.1 1 0 0 1 1 1 0 Benzoate membrane transport protein PKcGMP_CC PF16808.5 CEG40036.1 - 9.1 6.2 13.6 2.2 8.2 0.9 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TTL PF03133.15 CEG40037.1 - 7.9e-54 182.8 0.1 1.1e-53 182.2 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEG40037.1 - 1e-06 28.2 0.0 0.0048 16.2 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 CEG40037.1 - 3e-06 27.4 0.0 0.0058 16.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CEG40037.1 - 0.0026 17.4 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Vps51 PF08700.11 CEG40038.1 - 3.1e-07 30.4 2.1 6.2e-07 29.4 0.7 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Serine_rich PF08824.10 CEG40038.1 - 0.0089 16.0 0.9 0.022 14.7 0.9 1.7 1 0 0 1 1 1 1 Serine rich protein interaction domain Myb_DNA-binding PF00249.31 CEG40039.1 - 9.6e-07 28.9 0.0 0.052 13.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG40039.1 - 9.1e-06 25.5 0.1 0.064 13.2 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like aGPT-Pplase1 PF18723.1 CEG40040.1 - 7.3e-24 84.7 3.3 4.8e-23 82.0 3.3 2.0 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 PHD PF00628.29 CEG40040.1 - 1.1e-08 34.9 9.6 1.1e-08 34.9 9.6 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CEG40040.1 - 0.00051 19.5 2.4 0.00051 19.5 2.4 2.2 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 CEG40040.1 - 0.15 12.2 16.4 0.39 10.9 10.3 3.3 2 1 0 2 2 2 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 CEG40040.1 - 0.17 11.9 3.8 0.75 9.9 3.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger ADK_lid PF05191.14 CEG40040.1 - 0.47 10.5 2.7 0.5 10.4 0.4 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RanBP PF00641.18 CEG40040.1 - 1.8 7.9 9.8 0.84 9.0 0.2 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF2116 PF09889.9 CEG40040.1 - 2.8 8.0 25.1 2.1 8.4 4.5 3.6 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Prok-RING_1 PF14446.6 CEG40040.1 - 4.1 7.4 13.3 0.59 10.1 7.4 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 CEG40040.1 - 6.7 7.0 11.8 0.24 11.6 3.1 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_4 PF16866.5 CEG40040.1 - 7.7 6.7 14.1 5.1 7.3 8.5 2.9 2 0 0 2 2 2 0 PHD-finger TAL_FSA PF00923.19 CEG40041.1 - 2.7e-102 342.0 0.1 3.1e-102 341.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PC4 PF02229.16 CEG40042.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Mito_carr PF00153.27 CEG40045.1 - 4e-35 119.6 7.8 1.1e-10 41.3 0.0 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEG40045.1 - 0.012 14.8 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 0 Gammaproteobacterial serine protease MMR_HSR1_Xtn PF16897.5 CEG40046.1 - 3e-39 133.3 0.1 5.9e-39 132.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CEG40046.1 - 2.3e-15 56.7 0.1 7.7e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CEG40046.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CEG40046.1 - 4.1e-05 23.2 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEG40046.1 - 0.00051 20.2 0.3 0.012 15.7 0.0 2.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 CEG40046.1 - 0.021 14.3 0.1 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family TEP1_N PF05386.11 CEG40047.1 - 0.022 14.4 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 TEP1 N-terminal domain RXLR_WY PF18634.1 CEG40048.1 - 0.00018 21.4 2.6 0.00018 21.4 2.6 1.9 2 0 0 2 2 2 1 RXLR phytopathogen effector protein WY-domain Med31 PF05669.12 CEG40048.1 - 0.00091 19.2 0.6 0.011 15.8 0.1 2.6 2 0 0 2 2 2 1 SOH1 Aminotran_5 PF00266.19 CEG40050.1 - 1.2e-13 50.8 0.0 1.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEG40050.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II TMEM154 PF15102.6 CEG40052.1 - 0.008 16.1 0.4 0.008 16.1 0.4 3.4 2 2 1 3 3 3 1 TMEM154 protein family CrgA PF06781.12 CEG40052.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Cell division protein CrgA Orf78 PF06024.12 CEG40052.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) WD40 PF00400.32 CEG40053.1 - 1e-11 45.2 10.8 0.00022 21.9 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40053.1 - 3e-07 30.6 0.2 0.34 11.3 0.0 6.3 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TMF_DNA_bd PF12329.8 CEG40053.1 - 0.008 16.2 8.7 0.008 16.2 8.7 5.3 3 2 2 5 5 5 1 TATA element modulatory factor 1 DNA binding DUF2415 PF10313.9 CEG40053.1 - 0.085 12.8 0.1 5 7.1 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 CEG40054.1 - 4e-10 40.1 12.5 0.039 14.8 0.2 6.9 6 1 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 CEG40054.1 - 0.00035 20.5 0.1 0.043 13.7 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 CEG40054.1 - 0.057 13.1 2.5 12 5.6 0.0 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split HH_signal PF01085.18 CEG40054.1 - 0.073 12.7 2.6 0.12 12.0 2.6 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF2408 PF10303.9 CEG40054.1 - 0.87 10.1 6.1 2.1 8.9 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CT47 PF15623.6 CEG40054.1 - 2.1 8.1 8.6 4.6 7.0 8.6 1.5 1 0 0 1 1 1 0 Cancer/testis gene family 47 Aa_trans PF01490.18 CEG40055.1 - 2.5e-44 151.6 27.6 3.9e-44 151.0 27.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SK_channel PF03530.14 CEG40055.1 - 3.7 7.6 10.3 1.2 9.1 0.1 4.3 4 2 0 4 4 4 0 Calcium-activated SK potassium channel Aa_trans PF01490.18 CEG40056.1 - 9.2e-40 136.6 29.8 1.3e-39 136.1 29.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MscS_TM PF12794.7 CEG40056.1 - 8.3 5.2 16.4 1.2 7.9 0.2 3.3 3 1 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Aa_trans PF01490.18 CEG40057.1 - 1.2e-40 139.5 22.0 1.2e-40 139.5 22.0 2.6 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein LRR_4 PF12799.7 CEG40057.1 - 0.011 16.2 4.0 0.2 12.1 0.7 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG40057.1 - 4.8 7.0 10.3 6.9 6.5 1.5 4.0 3 1 1 4 4 4 0 Leucine rich repeat LSM PF01423.22 CEG40059.1 - 1.4e-19 69.5 1.2 1.7e-19 69.2 1.2 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CEG40059.1 - 0.014 15.3 0.6 0.024 14.5 0.6 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 CEG40059.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.6 CEG40059.1 - 0.029 14.5 0.2 0.036 14.2 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain KH_6 PF15985.5 CEG40060.1 - 2.7e-13 50.0 0.1 4.8e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CEG40060.1 - 9e-05 22.3 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain SL4P PF17618.2 CEG40060.1 - 0.16 12.0 0.1 0.82 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein EF-hand_8 PF13833.6 CEG40061.1 - 1.2e-10 41.1 0.3 6.7e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CEG40061.1 - 4.6e-07 30.2 1.5 0.00014 22.2 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG40061.1 - 0.00016 21.0 1.6 0.0003 20.1 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEG40061.1 - 0.0023 17.7 0.1 0.93 9.6 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG40061.1 - 0.054 13.0 0.1 0.19 11.3 0.1 2.0 1 0 0 1 1 1 0 EF hand Porin_3 PF01459.22 CEG40062.1 - 9.7e-41 140.0 13.8 1.1e-40 139.8 13.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin HA PF03457.14 CEG40063.1 - 1.1e-35 121.8 7.1 1.8e-05 24.9 0.0 8.2 8 0 0 8 8 8 7 Helicase associated domain FYVE PF01363.21 CEG40064.1 - 1.9e-11 43.9 10.4 1.9e-11 43.9 10.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 CEG40064.1 - 9e-07 29.6 0.0 2.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 CEG40064.1 - 0.0033 17.6 12.6 0.06 13.6 6.5 2.8 1 1 1 2 2 2 2 FYVE-type zinc finger Ysc84 PF04366.12 CEG40065.1 - 8.9e-33 112.8 0.3 1.5e-32 112.0 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator EF-hand_1 PF00036.32 CEG40065.1 - 0.003 17.0 0.1 0.0067 15.9 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG40065.1 - 0.072 13.1 0.1 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain YfaZ PF07437.11 CEG40065.1 - 0.11 12.1 2.1 0.54 9.8 0.5 2.1 1 1 1 2 2 2 0 YfaZ precursor Retrotrans_gag PF03732.17 CEG40066.1 - 8.2e-07 29.2 0.0 2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEG40066.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) ADK PF00406.22 CEG40068.1 - 2.8e-05 24.3 0.0 3.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase RNase_P_p30 PF01876.16 CEG40068.1 - 0.2 11.1 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit p30 Ammonium_transp PF00909.21 CEG40070.1 - 2.7e-113 378.7 34.1 3.8e-113 378.2 34.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.20 CEG40071.1 - 0.00059 19.4 4.1 0.0027 17.3 0.0 2.8 3 0 0 3 3 3 2 E1-E2 ATPase eIF-1a PF01176.19 CEG40072.1 - 1.5e-20 72.7 0.3 2.9e-20 71.8 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Armet PF10208.9 CEG40072.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding TPR_12 PF13424.6 CEG40073.1 - 2.5e-15 56.5 5.5 3.7e-05 23.9 0.6 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG40073.1 - 3.6e-14 52.1 6.7 0.00026 20.7 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40073.1 - 5.1e-08 32.5 8.0 0.009 16.2 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG40073.1 - 1.2e-07 31.3 6.5 0.88 9.8 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40073.1 - 2.9e-06 26.8 7.5 0.098 12.5 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40073.1 - 0.0011 18.9 2.6 0.83 9.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 CEG40073.1 - 0.0022 17.4 1.3 0.004 16.6 1.3 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP T6SS_VasJ PF16989.5 CEG40073.1 - 0.2 11.1 1.9 0.35 10.3 1.9 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Questin_oxidase PF14027.6 CEG40074.1 - 7e-43 147.5 4.4 8.9e-43 147.1 4.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like Proteasome PF00227.26 CEG40075.1 - 1.9e-46 158.0 0.0 2.1e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.29 CEG40076.1 - 4.2e-28 98.4 0.0 5.1e-21 75.5 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG40076.1 - 3.9e-05 23.9 2.4 0.00059 20.1 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG40076.1 - 4.2e-05 24.0 1.1 0.0015 18.9 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CEG40076.1 - 5.7e-05 23.1 0.0 0.025 14.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEG40076.1 - 0.0012 18.9 0.0 0.0036 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zot PF05707.12 CEG40076.1 - 0.0065 16.1 0.2 0.032 13.9 0.0 2.2 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_19 PF13245.6 CEG40076.1 - 0.0067 16.8 0.8 0.25 11.6 0.2 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CEG40076.1 - 0.0074 16.0 0.1 5.7 6.6 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CEG40076.1 - 0.011 15.2 0.3 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 CEG40076.1 - 0.012 15.4 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CEG40076.1 - 0.012 15.5 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 CEG40076.1 - 0.013 15.6 0.4 0.094 12.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CEG40076.1 - 0.02 14.6 1.8 1.9 8.1 0.1 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_lid_3 PF17862.1 CEG40076.1 - 0.022 14.6 2.6 0.37 10.6 0.5 2.8 2 0 0 2 2 2 0 AAA+ lid domain AAA_2 PF07724.14 CEG40076.1 - 0.034 14.3 0.1 0.17 12.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) CbiA PF01656.23 CEG40076.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 CEG40076.1 - 0.054 12.7 0.1 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 CEG40076.1 - 0.055 13.4 0.0 1.5 8.8 0.0 3.0 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 CEG40076.1 - 0.12 12.0 1.8 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CEG40076.1 - 0.12 12.1 0.1 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEG40076.1 - 0.17 12.3 0.1 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Peptidase_M1 PF01433.20 CEG40086.1 - 2.5e-07 30.5 0.2 4.6e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain RXLR PF16810.5 CEG40088.1 - 4.1e-05 24.0 0.5 0.011 16.2 0.3 2.5 2 0 0 2 2 2 2 RXLR phytopathogen effector protein, Avirulence activity Myb_DNA-binding PF00249.31 CEG40094.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF87 PF01935.17 CEG40094.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ANAPC4_WD40 PF12894.7 CEG40095.1 - 0.0088 16.3 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PALP PF00291.25 CEG40097.1 - 2.2e-66 224.3 0.0 3.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CEG40097.1 - 5.7e-16 58.7 0.1 1.2e-09 38.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain FYVE PF01363.21 CEG40098.1 - 0.041 14.0 19.2 0.041 14.0 17.6 1.9 2 1 0 2 2 2 0 FYVE zinc finger Siva PF05458.12 CEG40098.1 - 0.076 12.7 9.7 0.15 11.8 9.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1248 PF06852.12 CEG40098.1 - 0.17 11.4 0.0 1.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1248) FYVE_2 PF02318.16 CEG40098.1 - 0.18 12.0 13.9 1.4 9.2 14.0 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 CEG40098.1 - 7.2 6.8 16.3 0.28 11.4 8.7 2.5 3 0 0 3 3 3 0 B-box zinc finger NotI PF12183.8 CEG40099.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI MatE PF01554.18 CEG40101.1 - 4.1e-38 130.6 30.0 8.7e-32 110.0 11.2 3.3 3 0 0 3 3 3 3 MatE OTU PF02338.19 CEG40104.1 - 0.084 13.4 0.4 0.39 11.2 0.0 2.4 2 2 0 2 2 2 0 OTU-like cysteine protease 5_nucleotid PF05761.14 CEG40104.1 - 0.38 9.6 2.6 0.8 8.5 2.6 1.5 1 0 0 1 1 1 0 5' nucleotidase family DUF2388 PF09498.10 CEG40104.1 - 0.87 9.6 8.5 0.044 13.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) GspH PF12019.8 CEG40107.1 - 0.017 15.5 0.2 0.11 12.9 0.0 2.0 2 1 0 2 2 2 0 Type II transport protein GspH Ribosomal_S8 PF00410.19 CEG40108.1 - 0.13 12.3 0.6 0.32 10.9 0.0 2.0 2 1 0 2 2 2 0 Ribosomal protein S8 VirE PF05272.11 CEG40109.1 - 0.00048 19.9 0.0 0.00052 19.8 0.0 1.1 1 0 0 1 1 1 1 Virulence-associated protein E AAA_16 PF13191.6 CEG40109.1 - 0.0011 19.4 0.0 0.0012 19.2 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 CEG40109.1 - 0.0039 16.4 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 CEG40109.1 - 0.0075 15.5 0.0 0.0096 15.1 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 CEG40109.1 - 0.0079 16.7 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG40109.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CEG40109.1 - 0.032 13.5 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 CEG40109.1 - 0.081 12.2 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CEG40109.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CEG40109.1 - 0.086 13.2 0.4 0.24 11.8 0.2 1.7 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CEG40109.1 - 0.087 12.3 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CEG40109.1 - 0.095 13.2 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 CEG40109.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CEG40109.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Topoisom_bac PF01131.20 CEG40110.1 - 6.2e-91 305.4 0.2 8.7e-90 301.7 0.2 2.0 1 1 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CEG40110.1 - 7.7e-22 77.1 21.6 3.9e-11 42.9 5.0 4.2 4 0 0 4 4 4 2 GRF zinc finger Toprim PF01751.22 CEG40110.1 - 1.7e-18 66.7 0.0 3.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain FlgI PF02119.16 CEG40110.1 - 0.068 12.1 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Flagellar P-ring protein Toprim_4 PF13662.6 CEG40110.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Toprim domain Cytomega_gL PF01801.16 CEG40111.1 - 0.067 12.6 0.3 0.088 12.2 0.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L CorA PF01544.18 CEG40111.1 - 0.3 10.4 4.0 0.38 10.0 4.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF489 PF04356.12 CEG40111.1 - 0.96 9.4 5.4 2.2 8.3 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF489) Exo_endo_phos PF03372.23 CEG40112.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEG40112.1 - 0.036 13.9 0.0 0.24 11.3 0.0 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase PH PF00169.29 CEG40113.1 - 1.9e-12 47.6 0.4 1.3e-11 44.9 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CEG40113.1 - 0.00018 21.9 0.0 0.00072 19.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain WW PF00397.26 CEG40113.1 - 0.00044 20.3 4.4 0.0015 18.5 4.4 2.0 1 0 0 1 1 1 1 WW domain Prok-TraM PF09228.10 CEG40113.1 - 0.017 15.4 0.7 0.088 13.2 0.7 2.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Ssu72 PF04722.13 CEG40116.1 - 1.6e-55 187.7 0.1 1.8e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein zf-HC5HC2H_2 PF13832.6 CEG40118.1 - 1.3e-21 76.8 7.5 1.3e-20 73.6 0.1 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEG40118.1 - 6e-21 74.5 5.6 6.4e-18 64.8 0.0 3.1 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 CEG40118.1 - 1.5e-07 31.2 21.0 3.9e-06 26.7 6.1 3.3 4 0 0 4 4 4 2 PHD-finger zf-RING-like PF08746.11 CEG40118.1 - 1.4e-05 25.3 17.3 0.002 18.4 6.7 2.8 2 0 0 2 2 2 2 RING-like domain BET PF17035.5 CEG40118.1 - 1.9e-05 24.7 0.5 0.0016 18.6 0.0 3.0 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation PHD_2 PF13831.6 CEG40118.1 - 0.00014 21.3 4.6 0.00014 21.3 4.6 3.6 5 0 0 5 5 5 2 PHD-finger Pkinase PF00069.25 CEG40119.1 - 1.6e-71 240.8 0.0 2.4e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40119.1 - 1.3e-34 119.6 0.0 1.9e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEG40119.1 - 1.2e-06 29.1 0.7 1.2e-06 29.1 0.7 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CEG40119.1 - 3.9e-06 26.4 0.0 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG40119.1 - 0.0024 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CEG40119.1 - 0.0037 16.9 0.1 0.82 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEG40119.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VPS28 PF03997.12 CEG40120.1 - 9.5e-66 221.1 0.1 1.4e-65 220.5 0.1 1.3 1 0 0 1 1 1 1 VPS28 protein NIF PF03031.18 CEG40120.1 - 9e-41 139.2 1.3 1.7e-40 138.3 1.3 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1636 PF07845.11 CEG40120.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) SHOCT PF09851.9 CEG40120.1 - 0.15 11.8 0.2 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Short C-terminal domain MCM PF00493.23 CEG40122.1 - 4.3e-92 307.3 0.0 5e-91 303.8 0.0 2.3 1 1 0 1 1 1 1 MCM P-loop domain FH2 PF02181.23 CEG40122.1 - 9.2e-86 288.3 1.4 9.2e-86 288.3 1.4 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG40122.1 - 3.3e-69 232.2 32.6 1.2e-09 38.8 0.2 10.7 11 0 0 11 11 10 8 Subunit CCDC53 of WASH complex MCM_OB PF17207.3 CEG40122.1 - 3.6e-38 130.2 0.3 7.4e-38 129.2 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEG40122.1 - 3.6e-26 91.4 0.6 1e-25 89.9 0.6 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEG40122.1 - 3.7e-12 46.7 0.9 1.5e-11 44.8 0.9 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Drf_GBD PF06371.13 CEG40122.1 - 2.8e-09 36.8 0.0 1.1e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEG40122.1 - 6.1e-09 35.8 7.9 4.4e-08 33.0 1.1 3.0 3 0 0 3 3 3 2 Diaphanous FH3 Domain AAA_5 PF07728.14 CEG40122.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEG40122.1 - 1.4e-05 24.6 0.1 0.00053 19.4 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG40122.1 - 0.0031 17.4 0.0 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEG40122.1 - 0.0092 15.7 0.0 0.19 11.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-CHY PF05495.12 CEG40122.1 - 0.67 10.5 3.7 1.6 9.3 3.7 1.5 1 0 0 1 1 1 0 CHY zinc finger Mg_chelatase_C PF13335.6 CEG40122.1 - 0.85 10.3 6.1 0.17 12.6 1.1 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI C-terminal Elf1 PF05129.13 CEG40122.1 - 1.1 9.4 3.0 7.1 6.8 1.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RHS PF03527.14 CEG40122.1 - 2.5 7.9 7.4 61 3.5 0.1 5.2 6 0 0 6 6 6 0 RHS protein RCC1 PF00415.18 CEG40129.1 - 2.1e-102 335.6 27.7 1.8e-17 63.6 0.6 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG40129.1 - 2.7e-54 180.0 36.9 3.6e-10 39.4 0.6 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CEG40129.1 - 2.2e-25 89.0 0.6 1.5e-24 86.3 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CEG40129.1 - 8.2e-06 25.9 0.3 0.00024 21.2 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1921 PF09081.10 CEG40129.1 - 0.036 14.3 0.4 9.6 6.5 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) DUF4213 PF13938.6 CEG40129.1 - 1.8 8.9 15.9 17 5.7 0.2 5.2 2 2 2 4 4 4 0 Putative heavy-metal chelation DUF953 PF06110.11 CEG40132.1 - 0.094 12.3 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Glyco_hydro_28 PF00295.17 CEG40133.1 - 2.3e-61 207.7 12.9 3.1e-61 207.2 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 CEG40133.1 - 0.042 13.1 17.2 0.21 10.8 17.2 2.2 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) LRR_4 PF12799.7 CEG40134.1 - 0.00019 21.7 1.1 0.027 14.9 0.3 3.3 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG40134.1 - 0.0004 20.1 0.7 0.21 11.4 0.1 3.3 2 1 1 3 3 3 3 Leucine rich repeat Methyltransf_11 PF08241.12 CEG40135.1 - 5.2e-15 55.9 0.0 1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG40135.1 - 1.5e-12 48.1 0.0 3.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG40135.1 - 1.5e-09 37.8 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG40135.1 - 7.5e-07 29.8 0.0 1.3e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG40135.1 - 1.4e-05 24.6 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEG40135.1 - 9.1e-05 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 CEG40135.1 - 0.048 13.2 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PWWP PF00855.17 CEG40140.1 - 6.3e-15 55.4 0.1 2.4e-14 53.5 0.1 2.1 1 0 0 1 1 1 1 PWWP domain JAB PF01398.21 CEG40140.1 - 2.4e-10 40.4 0.0 9.8e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEG40140.1 - 4.8e-07 29.6 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2379 PF09543.10 CEG40140.1 - 0.44 10.7 4.2 0.45 10.7 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) YlbD_coat PF14071.6 CEG40140.1 - 0.76 10.0 3.4 34 4.7 0.0 2.8 2 0 0 2 2 2 0 Putative coat protein Cupin_8 PF13621.6 CEG40141.1 - 2.4e-09 37.3 0.2 6.3e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 Cupin-like domain Tudor-knot PF11717.8 CEG40141.1 - 0.0032 17.3 0.4 0.0032 17.3 0.4 3.1 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain AraC_binding PF02311.19 CEG40141.1 - 0.0074 16.2 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 1 AraC-like ligand binding domain JmjC PF02373.22 CEG40141.1 - 0.042 14.3 0.0 0.5 10.8 0.0 2.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 CEG40141.1 - 0.086 12.3 0.1 0.26 10.7 0.1 1.9 1 1 0 1 1 1 0 Cupin superfamily protein SMN PF06003.12 CEG40141.1 - 2.1 7.5 5.9 0.28 10.4 0.1 2.2 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) CAP PF00188.26 CEG40143.1 - 4.7e-15 56.5 1.2 6.6e-15 56.1 1.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF948 PF06103.11 CEG40143.1 - 0.00019 21.6 15.3 0.015 15.5 3.2 5.1 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 CEG40143.1 - 0.00041 20.2 5.5 0.0039 17.0 0.9 3.0 2 1 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain YqfQ PF14181.6 CEG40143.1 - 0.00076 19.7 23.4 0.31 11.2 4.1 4.9 2 1 2 4 4 4 3 YqfQ-like protein DASH_Duo1 PF08651.10 CEG40143.1 - 0.00079 19.2 0.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 2 DASH complex subunit Duo1 Retrotran_gag_3 PF14244.6 CEG40143.1 - 0.051 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1664 PF07889.12 CEG40143.1 - 0.11 12.5 0.7 1.3 9.1 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) RPW8 PF05659.11 CEG40143.1 - 0.17 11.6 0.2 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2203 PF09969.9 CEG40143.1 - 0.23 12.2 1.7 16 6.3 0.5 3.8 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.12 CEG40143.1 - 0.34 10.9 1.7 4.7 7.2 0.4 3.0 2 1 3 5 5 5 0 Laminin Domain II HCNGP PF07818.13 CEG40145.1 - 2.2e-27 95.6 0.3 3.6e-27 94.8 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein CBS PF00571.28 CEG40147.1 - 2.5e-17 63.1 0.3 3.8e-08 33.6 0.3 2.7 2 0 0 2 2 2 2 CBS domain Exo_endo_phos PF03372.23 CEG40147.1 - 4.8e-09 36.1 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dicty_CAR PF05462.11 CEG40147.1 - 1.9e-08 33.8 10.4 3.2e-08 33.1 10.4 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 CEG40147.1 - 1e-06 28.3 8.8 1.6e-06 27.6 8.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 CEG40147.1 - 0.49 9.7 12.3 0.85 8.9 12.3 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Aconitase PF00330.20 CEG40149.1 - 3.1e-64 217.7 0.4 1.6e-62 212.0 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEG40149.1 - 1.6e-16 60.8 0.0 7.7e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain zf-CCHC PF00098.23 CEG40150.1 - 0.00016 21.6 2.4 0.00029 20.8 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle PcF PF09461.10 CEG40151.1 - 0.16 12.3 0.7 0.24 11.8 0.1 1.5 2 0 0 2 2 2 0 Phytotoxin PcF protein Retrotran_gag_2 PF14223.6 CEG40154.1 - 6.4e-15 55.0 1.2 9.2e-15 54.5 1.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG40154.1 - 1.2e-05 25.1 2.8 2.2e-05 24.3 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEG40154.1 - 0.025 14.3 0.8 0.05 13.3 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEG40154.1 - 0.038 13.8 1.9 0.07 13.0 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEG40154.1 - 1.6 8.7 5.2 0.45 10.4 2.2 1.7 2 0 0 2 2 2 0 Zinc knuckle ZapB PF06005.12 CEG40155.1 - 0.0088 16.5 0.3 0.018 15.5 0.3 1.5 1 0 0 1 1 1 1 Cell division protein ZapB MctB PF11382.8 CEG40155.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB HALZ PF02183.18 CEG40155.1 - 0.029 14.6 0.5 0.055 13.7 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 CEG40155.1 - 0.042 13.6 0.1 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5558 PF17713.1 CEG40155.1 - 0.045 14.1 0.4 0.075 13.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5558) YabA PF06156.13 CEG40155.1 - 0.062 13.9 0.1 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA RVT_2 PF07727.14 CEG40155.1 - 0.086 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) bZIP_1 PF00170.21 CEG40155.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor WGR PF05406.15 CEG40155.1 - 0.13 12.3 0.7 0.24 11.5 0.7 1.4 1 0 0 1 1 1 0 WGR domain PikAIV_N PF18605.1 CEG40155.1 - 0.68 9.6 4.0 1.4 8.6 4.0 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain G-gamma PF00631.22 CEG40156.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 GGL domain GIT_SHD PF08518.11 CEG40156.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT RCC1 PF00415.18 CEG40159.1 - 1.1e-50 170.0 21.1 4e-11 43.4 0.0 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG40159.1 - 3.9e-24 83.9 29.1 4.7e-09 35.8 0.0 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 CEG40159.1 - 2.1e-12 47.3 0.9 4.6e-08 33.5 0.2 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ubiquitin PF00240.23 CEG40159.1 - 3.8e-10 39.4 0.0 9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family PI3_PI4_kinase PF00454.27 CEG40159.1 - 4.4e-10 39.8 0.0 8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.7 CEG40159.1 - 2.1e-09 37.9 0.0 7.4e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG40159.1 - 4.2e-07 29.8 0.4 5.9e-05 23.2 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CEG40159.1 - 6.5e-07 29.5 0.1 2.5e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG40159.1 - 5.8e-05 23.4 2.7 0.0072 16.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat E1-E2_ATPase PF00122.20 CEG40160.1 - 8.8e-11 41.6 0.1 3.9e-10 39.5 0.1 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CEG40160.1 - 0.00021 20.9 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF4448 PF14610.6 CEG40161.1 - 0.059 13.1 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Kinesin PF00225.23 CEG40162.1 - 1.9e-86 290.0 0.7 3e-86 289.4 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG40162.1 - 1.7e-18 67.0 0.0 5.5e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Syntaxin-18_N PF10496.9 CEG40162.1 - 0.043 14.1 1.4 0.74 10.1 0.6 3.0 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3074 PF11274.8 CEG40162.1 - 0.15 12.0 2.5 0.35 10.8 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Syntaxin-6_N PF09177.11 CEG40162.1 - 0.18 12.4 5.9 0.15 12.6 1.9 2.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Filament PF00038.21 CEG40162.1 - 0.47 10.0 16.4 0.11 12.1 12.8 1.7 2 0 0 2 2 2 0 Intermediate filament protein CorA PF01544.18 CEG40162.1 - 0.51 9.6 5.3 0.14 11.5 1.8 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SPT16 PF08644.11 CEG40162.1 - 0.55 10.4 0.0 0.55 10.4 0.0 2.8 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Allexi_40kDa PF05549.11 CEG40162.1 - 0.59 9.6 6.4 0.31 10.5 3.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 CEG40162.1 - 1 9.2 6.6 60 3.5 6.5 2.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Phage_Mu_Gam PF07352.12 CEG40162.1 - 2 8.3 11.5 0.24 11.3 0.4 3.8 4 1 0 4 4 4 0 Bacteriophage Mu Gam like protein DUF334 PF03904.13 CEG40162.1 - 3 7.3 6.8 5.7 6.4 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Atg14 PF10186.9 CEG40162.1 - 9.1 5.3 15.4 2.2 7.3 11.5 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 eIF3_subunit PF08597.10 CEG40163.1 - 2e-38 132.7 14.9 2.5e-38 132.3 14.9 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Alpha-2-MRAP_N PF06400.11 CEG40163.1 - 0.082 12.9 5.7 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain GvpL_GvpF PF06386.11 CEG40163.1 - 6.3 6.7 7.7 14 5.5 7.7 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CLPTM1 PF05602.12 CEG40164.1 - 5.4e-78 262.9 1.4 6.9e-78 262.6 1.4 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SBF PF01758.16 CEG40164.1 - 0.024 14.3 0.1 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 Sodium Bile acid symporter family PQ-loop PF04193.14 CEG40164.1 - 0.18 11.6 2.7 0.18 11.6 0.0 2.4 3 0 0 3 3 3 0 PQ loop repeat SURF6 PF04935.12 CEG40165.1 - 2.8e-22 79.5 43.6 2.8e-22 79.5 43.6 2.4 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CEG40165.1 - 1.3e-14 54.5 4.1 1.3e-14 54.5 4.1 5.8 4 3 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 GFO_IDH_MocA PF01408.22 CEG40166.1 - 1.9e-21 77.1 1.6 2.5e-21 76.7 0.7 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEG40166.1 - 2e-07 31.0 0.0 3.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 CEG40166.1 - 0.00011 22.6 0.2 0.00029 21.3 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 CEG40166.1 - 0.00016 22.2 0.7 0.0004 20.9 0.7 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CEG40166.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEG40166.1 - 0.005 16.9 0.4 0.022 14.8 0.2 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF4434 PF14488.6 CEG40166.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) zf-P11 PF03854.14 CEG40167.1 - 0.39 10.4 4.2 2.3 8.0 1.1 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-B_box PF00643.24 CEG40171.1 - 0.16 12.2 6.7 0.3 11.3 6.7 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-piccolo PF05715.13 CEG40171.1 - 5.3 7.3 7.7 1.7 8.8 4.4 2.0 2 0 0 2 2 2 0 Piccolo Zn-finger Asp_protease_2 PF13650.6 CEG40177.1 - 0.00012 22.7 0.0 0.0028 18.2 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG40177.1 - 0.00014 22.4 0.0 0.0015 19.1 0.0 2.7 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEG40177.1 - 0.0015 18.3 0.1 0.29 10.9 0.1 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEG40177.1 - 0.041 14.2 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease HigB-like_toxin PF05015.13 CEG40178.1 - 0.049 14.0 1.5 0.44 11.0 0.4 2.4 1 1 1 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB Kazal_2 PF07648.15 CEG40179.1 - 1.5e-09 37.8 4.0 4.2e-09 36.4 3.8 1.8 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG40179.1 - 9.7e-08 31.9 5.1 1.6e-07 31.2 5.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Baculo_PEP_C PF04513.12 CEG40180.1 - 0.00075 19.6 2.5 0.0011 19.0 2.5 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tht1 PF04163.12 CEG40180.1 - 0.0075 15.1 0.6 0.0091 14.8 0.6 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein eIF3m_C_helix PF18005.1 CEG40180.1 - 0.047 13.4 0.4 0.12 12.1 0.4 1.8 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Prominin PF05478.11 CEG40180.1 - 0.066 11.2 2.5 0.08 10.9 2.5 1.1 1 0 0 1 1 1 0 Prominin CCDC144C PF14915.6 CEG40180.1 - 0.083 12.0 8.4 0.55 9.3 8.4 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region XkdW PF09636.10 CEG40180.1 - 0.21 11.7 1.6 0.31 11.1 1.6 1.3 1 0 0 1 1 1 0 XkdW protein DUF4404 PF14357.6 CEG40180.1 - 0.3 11.7 5.6 4.9 7.9 5.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) CorA PF01544.18 CEG40180.1 - 0.35 10.2 6.6 0.43 9.8 6.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec2p PF06428.11 CEG40180.1 - 0.91 9.5 8.4 0.39 10.7 3.1 2.2 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Sas6_CC PF18594.1 CEG40180.1 - 3.8 7.4 7.0 4.1 7.3 1.9 2.9 2 1 1 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain bZIP_2 PF07716.15 CEG40181.1 - 0.071 13.2 0.3 0.071 13.2 0.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 CEG40181.1 - 0.086 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 CEG40181.1 - 0.088 12.7 2.2 1.6 8.7 0.8 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4472 PF14739.6 CEG40181.1 - 0.23 12.2 0.4 0.23 12.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 CEG40181.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 bZIP transcription factor Aminotran_5 PF00266.19 CEG40184.1 - 1.1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V EF-hand_1 PF00036.32 CEG40185.1 - 5.2e-15 53.8 15.2 1.5e-05 24.2 0.8 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CEG40185.1 - 1.4e-13 49.6 11.3 0.0001 21.9 0.6 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CEG40185.1 - 9.1e-12 43.9 15.9 1.3e-05 24.5 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CEG40185.1 - 1.8e-11 44.3 10.6 1e-09 38.7 3.5 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CEG40185.1 - 1.3e-08 34.6 8.3 0.00091 19.0 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEG40185.1 - 0.039 14.3 0.8 0.039 14.3 0.8 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CEG40185.1 - 0.042 14.2 0.2 0.095 13.0 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CEG40185.1 - 0.049 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Dockerin type I domain Na_H_Exchanger PF00999.21 CEG40186.1 - 2.6e-12 46.3 33.8 1.8e-10 40.2 21.9 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pyr_redox_3 PF13738.6 CEG40186.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3347 PF11827.8 CEG40186.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF4033 PF13225.6 CEG40187.1 - 0.01 15.8 2.0 0.94 9.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4033) WD40 PF00400.32 CEG40188.1 - 1.1e-08 35.6 4.5 1.3 10.0 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40188.1 - 0.035 14.4 0.0 4.9 7.5 0.0 3.7 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 CEG40188.1 - 0.038 13.6 0.2 8.5 5.9 0.1 2.8 2 1 2 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region FAM92 PF06730.11 CEG40189.1 - 1.1e-06 28.2 4.0 1.4e-06 27.9 4.0 1.1 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 CEG40189.1 - 0.0024 17.5 9.1 0.03 13.9 9.1 2.1 1 1 0 1 1 1 1 Vps5 C terminal like Myb_Cef PF11831.8 CEG40190.1 - 2.9e-40 138.3 8.8 2.9e-40 138.3 8.8 3.7 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CEG40190.1 - 8.9e-16 57.8 5.1 1.5e-07 31.4 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG40190.1 - 4.3e-14 52.5 5.6 7.8e-08 32.4 2.6 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain FAM178 PF14816.6 CEG40191.1 - 0.028 13.4 6.6 0.8 8.6 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function, FAM178 Retrotran_gag_2 PF14223.6 CEG40193.1 - 3.6e-22 78.5 0.0 4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MIP PF00230.20 CEG40194.1 - 5.6e-51 173.4 5.7 7.4e-51 173.0 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Mon2_C PF16206.5 CEG40195.1 - 1.8e-31 109.2 2.8 1.8e-31 109.2 2.8 3.6 3 1 1 4 4 4 1 C-terminal region of Mon2 protein DCB PF16213.5 CEG40195.1 - 3.7e-22 78.8 2.2 8.6e-20 71.1 0.4 5.2 6 0 0 6 6 6 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CEG40195.1 - 2.6e-14 53.4 0.0 2.6e-14 53.4 0.0 4.4 7 0 0 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CEG40195.1 - 1.8e-06 27.7 1.1 0.00057 19.7 0.0 4.6 3 1 0 4 4 4 1 Domain of unknown function (DUF1981) UME PF08064.13 CEG40195.1 - 5.1 7.1 11.6 2.6 8.0 0.1 5.1 5 0 0 5 5 5 0 UME (NUC010) domain RIO1 PF01163.22 CEG40197.1 - 0.02 14.5 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 CEG40197.1 - 0.024 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 CEG40197.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Terminase_4 PF05119.12 CEG40197.1 - 0.17 12.4 0.1 1.4 9.4 0.0 2.2 2 1 1 3 3 3 0 Phage terminase, small subunit Kdo PF06293.14 CEG40197.1 - 0.22 10.9 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CybS PF05328.12 CEG40198.1 - 0.045 13.4 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Erf4 PF10256.9 CEG40200.1 - 0.00021 21.4 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.28 CEG40201.1 - 6.9e-36 120.6 6.3 0.00014 21.5 0.0 8.5 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 CEG40201.1 - 2e-34 114.9 14.4 0.0013 18.7 0.0 10.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40201.1 - 6.7e-32 107.0 6.5 0.00084 19.4 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40201.1 - 3.5e-25 87.4 7.3 6.6e-08 32.1 0.0 8.3 4 2 4 8 8 8 6 TPR repeat TPR_12 PF13424.6 CEG40201.1 - 2e-20 72.8 14.0 0.00037 20.7 0.2 7.6 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40201.1 - 3.6e-20 72.3 0.2 0.00068 20.2 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG40201.1 - 3.8e-19 67.7 4.3 0.0017 19.0 0.0 8.5 3 3 5 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40201.1 - 1.8e-16 58.9 2.0 0.021 14.9 0.1 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40201.1 - 3.6e-16 59.1 9.5 0.0035 17.5 0.3 6.1 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEG40201.1 - 1e-15 58.0 2.4 0.021 15.3 0.0 6.9 5 3 3 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40201.1 - 5.4e-14 51.5 13.2 0.00096 19.4 0.0 9.2 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40201.1 - 3e-13 49.7 0.3 0.021 15.0 0.0 6.0 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG40201.1 - 9.4e-10 38.1 12.2 0.029 14.3 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG40201.1 - 1.7e-08 34.6 15.0 5.1 7.9 0.0 9.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG40201.1 - 2.5e-05 23.7 3.2 3.9 6.6 0.0 4.3 1 1 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 CEG40201.1 - 3.9e-05 22.8 2.7 0.022 13.7 0.3 3.0 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 CEG40201.1 - 0.0038 17.2 0.6 0.17 11.8 0.0 3.2 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 CEG40201.1 - 0.02 15.4 1.8 0.14 12.6 0.2 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain PknG_TPR PF16918.5 CEG40201.1 - 0.044 12.5 0.1 3.2 6.4 0.0 2.3 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG40201.1 - 0.047 13.8 1.1 19 5.4 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 CEG40201.1 - 0.06 13.4 2.1 0.19 11.8 0.3 3.0 2 2 1 3 3 2 0 Anaphase-promoting complex subunit 5 DUF4810 PF16068.5 CEG40201.1 - 0.083 13.4 1.2 62 4.2 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4810) TPR_3 PF07720.12 CEG40201.1 - 0.37 10.8 9.5 44 4.2 0.0 5.7 8 0 0 8 8 7 0 Tetratricopeptide repeat SNAP PF14938.6 CEG40201.1 - 0.98 8.8 7.1 2.5 7.4 0.2 3.3 2 2 1 3 3 3 0 Soluble NSF attachment protein, SNAP NSF PF02071.20 CEG40201.1 - 7.5 7.8 5.8 93 4.6 0.3 5.1 5 0 0 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat His_Phos_1 PF00300.22 CEG40202.1 - 4.7e-15 55.8 0.0 1.6e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Endonuclease_5 PF04493.14 CEG40204.1 - 3.6e-60 203.0 0.0 5.5e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DnaJ_C PF01556.18 CEG40204.1 - 1e-33 116.5 0.0 2e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG40204.1 - 6.4e-27 93.5 2.6 1.1e-26 92.7 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEG40204.1 - 5.3e-13 49.1 20.6 1e-12 48.2 20.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEG40204.1 - 0.0023 17.8 12.2 0.1 12.6 1.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 CEG40204.1 - 0.05 14.0 14.9 0.5 10.8 0.1 4.1 2 2 1 3 3 3 0 Restriction alleviation protein Lar zinc-ribbons_6 PF07191.12 CEG40204.1 - 0.072 13.1 5.8 0.19 11.7 5.8 1.7 1 0 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 CEG40204.1 - 0.16 11.7 5.5 0.79 9.4 0.3 2.5 1 1 2 3 3 3 0 Thaumarchaeal output domain 1 HypA PF01155.19 CEG40204.1 - 0.7 9.9 11.1 3.3 7.8 2.4 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 CEG40204.1 - 1.5 9.0 8.1 0.82 9.9 0.4 2.6 1 1 1 2 2 2 0 zinc RING finger of MSL2 Glyco_hydro_17 PF00332.18 CEG40210.1 - 4.8e-06 26.4 3.5 0.00069 19.3 0.2 3.1 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 Chordopox_A20R PF05941.13 CEG40210.1 - 0.11 11.4 0.1 0.32 9.9 0.0 1.8 1 1 1 2 2 2 0 Chordopoxvirus A20R protein MIP-T3 PF10243.9 CEG40211.1 - 4e-74 245.8 2.4 7.4e-37 125.8 0.1 3.3 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 CEG40211.1 - 8.1e-38 129.8 5.1 2.1e-37 128.4 5.1 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Tsc35 PF15079.6 CEG40211.1 - 0.0081 15.8 1.7 0.022 14.3 1.7 1.7 1 0 0 1 1 1 1 Testis-specific protein 35 DUF1664 PF07889.12 CEG40211.1 - 0.017 15.2 1.8 0.034 14.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG17 PF04108.12 CEG40211.1 - 0.017 14.2 2.3 0.027 13.6 2.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF1732 PF08340.11 CEG40211.1 - 0.038 14.0 0.3 0.37 10.8 0.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) SOGA PF11365.8 CEG40211.1 - 0.046 14.8 1.6 0.19 12.9 1.6 2.1 1 0 0 1 1 1 0 Protein SOGA ANAPC4 PF12896.7 CEG40211.1 - 0.051 13.1 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Spc7 PF08317.11 CEG40211.1 - 0.38 9.6 6.8 0.81 8.5 6.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CEG40211.1 - 0.67 10.1 6.6 0.27 11.4 3.6 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CEG40211.1 - 1.2 9.6 5.5 54 4.3 4.4 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF641 PF04859.12 CEG40211.1 - 1.7 9.0 6.7 4.8 7.5 6.7 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Ist1 PF03398.14 CEG40212.1 - 1.7e-58 197.2 1.2 2.5e-58 196.6 1.2 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF5528 PF17666.1 CEG40212.1 - 0.38 10.7 1.9 0.8 9.7 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5528) Glycophorin_A PF01102.18 CEG40212.1 - 4.3 7.6 8.9 8.8 6.6 0.5 3.3 3 0 0 3 3 3 0 Glycophorin A zf-MYND PF01753.18 CEG40215.1 - 1.1e-09 38.2 18.1 2.3e-09 37.2 18.1 1.6 1 0 0 1 1 1 1 MYND finger CSN8_PSD8_EIF3K PF10075.9 CEG40216.1 - 4.3e-27 94.9 0.4 5.7e-27 94.5 0.4 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ETC_C1_NDUFA4 PF04800.12 CEG40216.1 - 0.007 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region SAC3_GANP PF03399.16 CEG40216.1 - 0.039 13.3 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family PCI PF01399.27 CEG40216.1 - 0.044 14.3 0.0 0.083 13.4 0.0 1.6 1 1 0 1 1 1 0 PCI domain PRANC PF09372.10 CEG40216.1 - 0.094 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 PRANC domain Ion_trans PF00520.31 CEG40217.1 - 0.0039 16.4 5.9 0.0058 15.9 5.9 1.1 1 0 0 1 1 1 1 Ion transport protein His_biosynth PF00977.21 CEG40218.1 - 6.7e-29 101.0 0.1 7.8e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CEG40218.1 - 0.037 13.4 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PRAI PF00697.22 CEG40218.1 - 0.09 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF5318 PF17249.2 CEG40218.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Pkinase PF00069.25 CEG40219.1 - 2e-47 161.8 0.0 3e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40219.1 - 2.9e-17 62.8 0.0 4.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG40219.1 - 0.0011 19.0 1.8 0.0019 18.2 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG40219.1 - 0.0011 18.4 0.1 0.0029 17.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG40219.1 - 0.038 13.6 0.3 0.18 11.4 0.1 2.2 2 1 0 2 2 2 0 RIO1 family NAM-associated PF14303.6 CEG40219.1 - 0.096 13.4 0.9 0.22 12.3 0.9 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Podovirus_Gp16 PF05894.12 CEG40219.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) WD40 PF00400.32 CEG40220.1 - 2.3e-13 50.3 28.9 0.00016 22.4 1.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40220.1 - 2.1e-06 27.9 0.2 0.012 15.8 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG40220.1 - 0.00018 20.3 10.9 0.087 11.4 1.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG40220.1 - 0.0084 15.1 0.4 0.9 8.4 0.0 2.8 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Apolipoprotein PF01442.18 CEG40221.1 - 1.8e-05 24.7 16.7 0.0025 17.7 13.4 2.6 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEG40221.1 - 4.3e-05 24.0 17.8 0.27 11.9 0.9 3.7 2 1 1 3 3 3 3 Bacterial protein of unknown function (DUF883) Syntaxin_2 PF14523.6 CEG40221.1 - 0.00044 20.6 0.9 0.00044 20.6 0.9 2.4 2 1 1 3 3 3 1 Syntaxin-like protein YtxH PF12732.7 CEG40221.1 - 0.01 16.3 21.8 2 9.0 0.3 4.7 3 1 0 3 3 3 0 YtxH-like protein CorA PF01544.18 CEG40221.1 - 0.02 14.3 1.2 0.2 10.9 0.0 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Phasin PF05597.11 CEG40221.1 - 0.021 14.8 2.9 0.021 14.8 2.9 3.5 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1640 PF07798.11 CEG40221.1 - 0.055 13.5 5.3 0.056 13.5 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) LPP PF04728.13 CEG40221.1 - 0.063 13.7 9.7 0.28 11.6 0.3 3.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Fungal_TACC PF12709.7 CEG40221.1 - 0.083 13.3 7.2 2.3 8.7 0.0 4.1 3 2 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins ApoLp-III PF07464.11 CEG40221.1 - 0.097 12.8 11.5 0.46 10.6 0.8 3.0 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 CEG40221.1 - 0.098 10.6 2.4 1.9 6.3 1.1 2.3 2 1 0 2 2 2 0 Prominin HSBP1 PF06825.12 CEG40221.1 - 0.1 12.5 1.9 5.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.11 CEG40221.1 - 0.12 13.0 5.3 0.37 11.4 0.6 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 CEG40221.1 - 0.14 12.2 7.3 0.62 10.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 CEG40221.1 - 0.14 11.6 11.7 0.048 13.2 8.1 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Ax_dynein_light PF10211.9 CEG40221.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.0 2 1 1 3 3 3 0 Axonemal dynein light chain DUF948 PF06103.11 CEG40221.1 - 0.6 10.4 5.2 37 4.7 2.9 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 CEG40221.1 - 0.68 9.2 7.3 0.2 11.0 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CEG40221.1 - 2 7.9 7.8 2.8 7.4 3.8 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF1451 PF07295.11 CEG40221.1 - 2.1 8.4 9.0 0.84 9.7 3.8 2.8 2 1 0 2 2 2 0 Zinc-ribbon containing domain Spc7 PF08317.11 CEG40221.1 - 2.2 7.1 12.5 1.7 7.5 6.8 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3958 PF13125.6 CEG40221.1 - 2.6 8.3 7.0 2.9 8.2 2.2 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF3958) T3SS_needle_F PF09392.10 CEG40221.1 - 3.4 7.9 5.2 37 4.6 0.2 3.4 3 1 0 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ALIX_LYPXL_bnd PF13949.6 CEG40222.1 - 0.01 15.2 0.6 0.013 14.8 0.6 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF5482 PF17579.2 CEG40222.1 - 0.032 14.1 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5482) RVT_2 PF07727.14 CEG40223.1 - 1.6e-06 28.0 0.1 1.8e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trp_dioxygenase PF03301.13 CEG40225.1 - 0.49 9.7 0.9 0.96 8.7 0.9 1.4 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase T3SS_needle_E PF08988.10 CEG40226.1 - 0.0061 16.7 0.5 0.013 15.6 0.5 1.6 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle UPF0564 PF10595.9 CEG40228.1 - 1.2e-11 44.3 58.3 1.2e-11 44.3 58.3 3.6 2 2 1 3 3 3 1 Uncharacterised protein family UPF0564 HupE_UreJ_2 PF13795.6 CEG40229.1 - 0.00016 21.3 0.6 0.00096 18.8 0.1 2.2 2 0 0 2 2 2 1 HupE / UreJ protein DUF1338 PF07063.13 CEG40229.1 - 0.074 12.2 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) SieB PF14163.6 CEG40229.1 - 0.53 9.8 4.0 1.4 8.4 0.2 2.8 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF4199 PF13858.6 CEG40229.1 - 1.1 9.7 5.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Cys_Met_Meta_PP PF01053.20 CEG40231.1 - 6.2e-36 123.7 0.0 8.1e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEG40231.1 - 3.2e-06 26.6 0.0 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.31 CEG40232.1 - 7.3e-13 48.5 0.2 1.4e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG40232.1 - 2.3e-05 24.5 0.2 0.13 12.5 0.0 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG40232.1 - 0.0055 16.6 0.1 3.4 7.6 0.0 2.7 2 0 0 2 2 2 2 Myb DNA-binding like Leptin PF02024.15 CEG40232.1 - 0.12 12.2 0.1 0.51 10.1 0.0 2.1 2 1 0 2 2 2 0 Leptin Allantoicase PF03561.15 CEG40233.1 - 3.4e-88 293.0 0.0 3.1e-44 150.4 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DUF512 PF04459.12 CEG40233.1 - 0.11 11.8 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Pkinase PF00069.25 CEG40234.1 - 1.3e-57 195.2 0.0 2.1e-57 194.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40234.1 - 1.9e-24 86.4 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CEG40234.1 - 1.2e-05 25.0 0.2 6.2e-05 22.7 0.0 2.0 1 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CEG40234.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.26 CEG40235.1 - 2e-26 91.6 0.7 3.1e-26 90.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TPR_2 PF07719.17 CEG40236.1 - 2.3e-31 105.3 14.4 0.00029 20.7 0.0 12.6 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 CEG40236.1 - 5.1e-29 98.5 27.2 0.00014 22.4 0.1 13.1 6 5 8 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40236.1 - 6.3e-27 94.0 22.2 9.9e-06 26.1 0.3 8.4 7 2 3 10 10 9 9 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40236.1 - 4.4e-26 91.2 7.9 0.00086 19.8 0.2 7.8 5 1 4 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 CEG40236.1 - 3.5e-22 78.5 18.6 7.7e-05 22.9 2.0 8.9 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40236.1 - 1.3e-20 72.2 1.7 0.00014 22.0 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40236.1 - 7e-19 66.4 2.1 0.0013 18.8 0.0 9.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG40236.1 - 5.6e-16 58.0 17.0 0.14 12.8 0.0 10.5 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40236.1 - 1e-15 56.8 5.0 0.0028 17.4 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40236.1 - 1.7e-15 56.9 16.9 0.013 15.6 0.1 6.6 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40236.1 - 1.3e-13 50.3 6.3 0.0024 17.5 0.0 7.3 7 1 1 8 8 8 2 TPR repeat TPR_15 PF13429.6 CEG40236.1 - 6.1e-09 35.5 15.2 0.00024 20.4 4.7 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40236.1 - 7e-09 35.8 3.6 0.027 14.7 0.1 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CEG40236.1 - 4e-07 29.7 8.5 0.018 14.5 0.0 4.3 1 1 1 2 2 2 2 MalT-like TPR region Suf PF05843.14 CEG40236.1 - 3.1e-06 27.4 0.6 0.49 10.3 0.0 4.4 2 2 3 5 5 5 2 Suppressor of forked protein (Suf) Fis1_TPR_C PF14853.6 CEG40236.1 - 0.00014 21.8 2.7 1.7 8.8 0.2 5.4 6 0 0 6 6 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 CEG40236.1 - 0.0027 16.7 6.0 1.3 7.9 0.1 4.6 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 HrpJ PF07201.11 CEG40236.1 - 0.006 16.9 0.8 0.035 14.4 0.3 2.4 2 0 0 2 2 2 1 HrpJ-like domain TPR_20 PF14561.6 CEG40236.1 - 0.013 15.8 5.5 8.1 6.9 0.0 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40236.1 - 0.016 15.2 15.2 1.3 9.2 0.1 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG40236.1 - 0.018 14.9 26.4 0.093 12.6 0.1 7.3 8 0 0 8 8 6 0 Tetratricopeptide repeat Tcf25 PF04910.14 CEG40236.1 - 0.04 13.0 0.8 0.17 10.9 0.0 2.3 3 0 0 3 3 3 0 Transcriptional repressor TCF25 ChAPs PF09295.10 CEG40236.1 - 0.055 12.5 0.6 0.55 9.2 0.0 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 CEG40236.1 - 0.25 11.4 11.4 12 6.1 0.7 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CEG40236.1 - 1.4 9.0 5.1 3.9 7.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 CEG40236.1 - 2.2 8.7 12.9 1.9 8.9 0.3 4.6 2 2 1 4 4 4 0 Bacterial transcriptional activator domain SMBP PF16785.5 CEG40236.1 - 7.9 6.7 10.5 80 3.5 0.0 5.2 4 1 1 5 5 5 0 Small metal-binding protein FSH1 PF03959.13 CEG40239.1 - 7.2e-41 140.2 0.0 8.2e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CEG40239.1 - 0.00038 21.1 0.1 0.00049 20.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CEG40239.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CEG40239.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 CEG40239.1 - 0.077 12.3 0.5 5.9 6.1 0.1 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG40239.1 - 0.093 12.4 0.1 0.36 10.4 0.0 1.8 1 1 0 2 2 2 0 alpha/beta hydrolase fold Ank PF00023.30 CEG40240.1 - 5.8e-12 45.5 1.8 0.00012 22.3 1.3 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CEG40240.1 - 2e-11 44.3 0.4 6e-11 42.8 0.4 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) C2 PF00168.30 CEG40240.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ank_3 PF13606.6 CEG40240.1 - 2.6e-09 36.5 0.6 0.0026 18.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEG40240.1 - 1.8e-08 34.4 1.3 0.0017 18.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG40240.1 - 3.9e-08 33.7 1.2 5.7e-05 23.6 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) WW PF00397.26 CEG40240.1 - 3.1e-07 30.3 1.3 5.8e-07 29.5 1.3 1.5 1 0 0 1 1 1 1 WW domain Erp_C PF06780.11 CEG40240.1 - 0.49 10.4 3.0 0.3 11.1 0.6 1.9 2 0 0 2 2 2 0 Erp protein C-terminus DSPc PF00782.20 CEG40241.1 - 2.2e-14 53.4 0.0 3.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG40241.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CEG40241.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Peripla_BP_4 PF13407.6 CEG40241.1 - 0.042 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Y_phosphatase3 PF13350.6 CEG40241.1 - 0.05 13.6 0.1 0.14 12.1 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Tn7_Tnp_TnsA_C PF08721.11 CEG40242.1 - 0.16 12.6 2.8 1.5 9.5 0.1 2.9 2 0 0 2 2 2 0 TnsA endonuclease C terminal DUF3019 PF11456.8 CEG40245.1 - 0.032 14.7 2.6 0.032 14.7 2.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3019) SKN1 PF03935.15 CEG40246.1 - 6.6e-62 209.5 16.4 3.1e-40 138.0 7.6 4.5 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Bromo_TP PF07524.13 CEG40247.1 - 1.3e-14 54.0 0.0 3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 CEG40247.1 - 4.2e-11 43.2 0.6 1.3e-10 41.7 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 CEG40247.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Histone-fold protein CBFD_NFYB_HMF PF00808.23 CEG40247.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAD_binding_2 PF00890.24 CEG40248.1 - 7.1e-123 410.8 2.2 9.1e-123 410.4 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CEG40248.1 - 1.8e-41 141.1 2.8 2.8e-41 140.5 2.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CEG40248.1 - 4.8e-05 22.7 0.3 0.017 14.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 CEG40248.1 - 0.0005 19.4 0.6 0.0011 18.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEG40248.1 - 0.0041 16.3 4.0 0.024 13.7 3.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 CEG40248.1 - 0.013 15.1 0.8 0.018 14.6 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG40248.1 - 0.018 13.8 1.1 0.065 11.9 1.1 1.9 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 CEG40248.1 - 0.041 13.1 0.4 0.041 13.1 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 CEG40248.1 - 0.34 9.9 3.0 0.46 9.5 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CEG40248.1 - 1.2 8.4 4.3 2.2 7.5 4.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5431 PF17496.2 CEG40249.1 - 0.063 13.4 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5431) UCH PF00443.29 CEG40251.1 - 2.2e-36 125.7 0.1 3.6e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG40251.1 - 8.9e-12 45.2 1.0 6.4e-11 42.4 0.2 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEG40251.1 - 2.1e-07 31.2 4.8 4.9e-07 30.0 2.0 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein ubiquitin PF00240.23 CEG40251.1 - 0.0001 21.9 0.1 0.00021 21.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG40251.1 - 0.0015 18.3 0.1 0.0034 17.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 CEG40251.1 - 0.031 14.1 2.7 0.083 12.7 0.2 2.4 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain OST_IS PF18246.1 CEG40251.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain Bact_lectin PF18483.1 CEG40253.1 - 2.6e-19 70.0 0.0 5.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEG40253.1 - 5.4e-19 68.7 0.1 2.6e-18 66.5 0.1 2.0 2 1 0 2 2 2 1 Legume lectin domain ADK PF00406.22 CEG40254.1 - 9.3e-90 298.5 0.0 7.9e-44 149.4 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase DUF4821 PF16092.5 CEG40254.1 - 6.1e-75 252.2 0.1 1.5e-69 234.6 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4821) AAA_17 PF13207.6 CEG40254.1 - 1.1e-46 158.6 0.0 4.6e-22 78.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CEG40254.1 - 7.9e-14 52.3 0.0 1.9e-05 25.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEG40254.1 - 4.3e-08 33.4 0.8 0.052 13.7 0.0 5.2 3 2 2 5 5 5 3 AAA domain ADK_lid PF05191.14 CEG40254.1 - 4.1e-07 29.9 0.2 0.042 13.8 0.0 3.2 2 1 0 2 2 2 2 Adenylate kinase, active site lid Hydin_ADK PF17213.3 CEG40254.1 - 3.3e-06 27.5 4.9 4.5 7.5 0.4 4.4 2 2 2 4 4 4 4 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 CEG40254.1 - 8.2e-05 22.4 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 2 Cytidylate kinase Pyr_redox_2 PF07992.14 CEG40254.1 - 0.003 16.9 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thymidylate_kin PF02223.17 CEG40254.1 - 0.093 12.4 0.1 31 4.2 0.0 3.5 4 0 0 4 4 4 0 Thymidylate kinase Myotub-related PF06602.14 CEG40255.1 - 2e-120 402.0 0.0 3.4e-120 401.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CEG40255.1 - 5.3e-16 58.5 14.0 1.2e-15 57.4 14.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 CEG40255.1 - 2.3e-14 53.5 0.0 6.8e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain DSPc PF00782.20 CEG40255.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEG40255.1 - 0.008 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family CC2D2AN-C2 PF15625.6 CEG40255.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain PhyH PF05721.13 CEG40256.1 - 4.5e-18 66.3 0.0 1.4e-17 64.6 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.11 CEG40256.1 - 0.0027 17.4 0.0 0.0092 15.7 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Inhibitor_I68 PF10468.9 CEG40256.1 - 0.063 13.7 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Sugar_tr PF00083.24 CEG40259.1 - 3.8e-32 111.7 20.6 9.3e-27 94.0 6.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG40259.1 - 2.9e-20 72.5 44.1 5.9e-15 55.0 21.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Ribosomal_L11 PF00298.19 CEG40260.1 - 3.2e-29 101.2 0.2 4.4e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CEG40260.1 - 1.7e-26 91.8 0.2 4.3e-26 90.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 CEG40261.1 - 7.7e-70 235.3 0.0 1.1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40261.1 - 7.7e-38 130.2 0.0 1.5e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG40261.1 - 1.9e-07 30.4 0.2 2.9e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEG40261.1 - 9.7e-05 21.8 0.1 0.00027 20.3 0.1 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEG40261.1 - 0.0097 15.5 0.7 0.95 9.0 0.3 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEG40261.1 - 0.033 14.1 0.2 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Scs3p PF10261.9 CEG40263.1 - 0.00011 21.8 1.6 0.00011 21.8 1.6 1.7 1 1 1 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM Actin PF00022.19 CEG40264.1 - 1.9e-143 478.0 0.0 6.4e-143 476.2 0.0 1.7 1 1 0 1 1 1 1 Actin DUF2097 PF09870.9 CEG40265.1 - 0.024 14.8 0.4 0.031 14.5 0.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) YbhQ PF11076.8 CEG40267.1 - 0.16 12.0 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Fascin PF06268.13 CEG40268.1 - 9.5e-05 22.6 0.1 0.0002 21.5 0.1 1.5 1 0 0 1 1 1 1 Fascin domain Peptidase_M10 PF00413.24 CEG40268.1 - 0.0084 16.0 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Matrixin FYVE PF01363.21 CEG40269.1 - 0.00079 19.5 7.7 0.00079 19.5 7.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger HrpB7 PF09486.10 CEG40269.1 - 0.068 13.6 0.5 0.11 12.9 0.5 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DZR PF12773.7 CEG40269.1 - 0.97 9.5 7.1 12 6.0 7.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon FYVE_2 PF02318.16 CEG40269.1 - 2.8 8.2 18.2 0.37 11.0 9.1 3.2 2 2 1 3 3 3 0 FYVE-type zinc finger RVT_2 PF07727.14 CEG40271.1 - 1.2e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF818 PF05677.12 CEG40271.1 - 0.21 10.5 0.5 0.49 9.3 0.2 1.6 1 1 1 2 2 2 0 Chlamydia CHLPS protein (DUF818) Rhabdo_M2 PF04785.12 CEG40271.1 - 0.53 9.6 2.2 16 4.7 0.1 2.4 1 1 1 2 2 2 0 Rhabdovirus matrix protein M2 PLDc_2 PF13091.6 CEG40272.1 - 7.4e-15 55.0 0.1 9.9e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEG40272.1 - 6.5e-09 35.6 2.7 0.00093 19.3 0.4 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif PPR_3 PF13812.6 CEG40273.1 - 4.2e-08 33.2 0.4 0.099 12.7 0.0 4.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 CEG40273.1 - 2.5e-07 30.3 1.9 1.5e-06 27.7 0.5 2.1 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEG40273.1 - 2.9e-07 30.3 1.1 9 6.8 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.6 CEG40273.1 - 6.2e-06 26.3 5.3 1.4 9.2 0.1 5.6 3 2 3 6 6 6 2 PPR repeat family Smr PF01713.21 CEG40273.1 - 0.00052 20.3 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Smr domain ANAPC3 PF12895.7 CEG40273.1 - 0.0013 18.9 0.1 0.26 11.5 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 RLL PF10036.9 CEG40273.1 - 0.0022 17.9 2.3 0.0022 17.9 2.3 1.8 2 1 1 3 3 3 1 RNA transcription, translation and transport factor protein TPR_14 PF13428.6 CEG40273.1 - 0.0083 16.9 0.1 14 6.9 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat EST1 PF10374.9 CEG40273.1 - 0.047 14.3 1.8 0.23 12.1 0.1 2.7 2 1 0 2 2 2 0 Telomerase activating protein Est1 Ribosomal_L4 PF00573.22 CEG40274.1 - 1.2e-40 139.3 0.7 2.1e-40 138.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CEG40274.1 - 5.4e-28 96.9 1.9 5.4e-28 96.9 1.9 1.9 1 1 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain MIR PF02815.19 CEG40277.1 - 5.4e-12 45.9 0.3 6.7e-11 42.4 0.2 2.3 1 1 1 2 2 2 2 MIR domain PDZ_6 PF17820.1 CEG40278.1 - 8.6e-11 41.5 0.1 1.7e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG40278.1 - 1.1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CEG40278.1 - 0.00038 20.7 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 CEG40278.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain XRN_M PF17846.1 CEG40279.1 - 4.9e-150 500.3 0.0 9.3e-150 499.4 0.0 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CEG40279.1 - 1.6e-96 322.4 1.2 1.7e-96 322.4 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus adh_short PF00106.25 CEG40282.1 - 3.3e-17 62.6 0.0 4.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase HTH_Tnp_Tc5 PF03221.16 CEG40282.1 - 9.4e-12 44.8 0.1 6e-11 42.2 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain adh_short_C2 PF13561.6 CEG40282.1 - 2.2e-07 30.7 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LacI PF00356.21 CEG40282.1 - 0.048 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DEAD PF00270.29 CEG40283.1 - 1.7e-48 164.7 0.1 3.9e-48 163.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG40283.1 - 5.1e-23 81.5 0.0 6e-22 78.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CEG40283.1 - 6e-12 45.6 3.5 6e-12 45.6 3.5 3.0 4 0 0 4 4 4 1 DBP10CT (NUC160) domain PA26 PF04636.13 CEG40283.1 - 7.3 5.4 11.5 20 4.0 11.5 1.7 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Cyclin PF08613.11 CEG40284.1 - 1.2e-14 55.0 0.8 2.8e-14 53.8 0.8 1.8 1 1 0 1 1 1 1 Cyclin WW PF00397.26 CEG40284.1 - 4.7e-08 33.0 2.4 4.7e-08 33.0 2.4 1.8 2 0 0 2 2 2 1 WW domain Cyclin_N PF00134.23 CEG40284.1 - 6e-07 29.2 1.6 1.2e-06 28.3 1.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RGI1 PF10843.8 CEG40284.1 - 0.044 13.4 0.2 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 Respiratory growth induced protein 1 DUF963 PF06131.11 CEG40284.1 - 0.053 13.0 23.6 2.4 7.7 11.0 3.8 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Atg8 PF02991.16 CEG40284.1 - 0.073 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like TpcC PF12642.7 CEG40284.1 - 0.073 12.8 2.1 1.6 8.5 2.2 2.5 1 1 0 1 1 1 0 Conjugative transposon protein TcpC Pkinase PF00069.25 CEG40285.1 - 2.8e-55 187.5 0.0 1.9e-54 184.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40285.1 - 1e-35 123.3 0.0 1.9e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40285.1 - 2.1e-09 37.1 0.0 4.5e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG40285.1 - 1.3e-06 27.4 0.0 2.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG40285.1 - 0.077 12.3 0.1 0.18 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CEG40285.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_8 PF13855.6 CEG40286.1 - 3.7e-48 161.1 78.2 3.6e-09 36.2 6.9 10.2 5 2 7 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 CEG40286.1 - 7.6e-32 108.8 78.8 1.7e-05 25.1 2.1 12.5 9 2 6 15 15 15 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG40286.1 - 3.4e-06 26.8 65.2 0.71 10.6 0.1 16.2 16 2 1 17 17 17 6 Leucine Rich Repeat Med4 PF10018.9 CEG40286.1 - 2.3 7.8 11.9 1.6 8.4 0.3 2.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RNase_T PF00929.24 CEG40287.1 - 2.8e-12 47.5 0.0 5.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease zf-CCCH_4 PF18044.1 CEG40287.1 - 6.4e-08 32.2 12.8 0.00091 19.0 2.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CEG40287.1 - 7.4e-06 25.7 13.9 0.00052 19.9 1.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DNA_pol_A_exo1 PF01612.20 CEG40287.1 - 0.00034 20.4 0.1 0.0028 17.4 0.1 2.2 1 1 0 1 1 1 1 3'-5' exonuclease zf_CCCH_4 PF18345.1 CEG40287.1 - 0.00055 19.9 17.5 0.036 14.1 4.3 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CEG40287.1 - 0.0023 18.1 3.8 0.84 9.9 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger containing family YugN PF08868.10 CEG40287.1 - 0.024 14.6 0.1 0.071 13.0 0.1 1.8 2 0 0 2 2 2 0 YugN-like family zf-CCCH_2 PF14608.6 CEG40287.1 - 0.054 14.0 16.8 0.087 13.3 3.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG40287.1 - 0.089 13.5 6.8 0.34 11.6 0.2 2.4 1 1 1 2 2 2 0 Torus domain CCT PF06203.14 CEG40288.1 - 8.3e-18 64.2 8.1 1.5e-17 63.4 8.1 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 CEG40288.1 - 0.38 10.7 3.4 0.72 9.8 3.4 1.4 1 0 0 1 1 1 0 Divergent CCT motif zf-C3HC4 PF00097.25 CEG40290.1 - 9.7e-09 35.0 6.8 9.7e-09 35.0 6.8 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG40290.1 - 2.4e-08 33.8 7.9 3.5e-08 33.3 4.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG40290.1 - 2.3e-07 30.6 4.1 2.3e-07 30.6 4.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG40290.1 - 7.4e-07 29.4 2.6 2.5e-06 27.7 2.6 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG40290.1 - 8.9e-07 28.8 6.0 8.9e-07 28.8 6.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG40290.1 - 9.9e-07 29.0 8.1 9.9e-07 29.0 8.1 2.2 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG40290.1 - 1e-05 25.2 10.9 1e-05 25.2 10.9 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG40290.1 - 5.1e-05 23.4 5.8 5.1e-05 23.4 5.8 2.5 3 1 0 3 3 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEG40290.1 - 0.00019 21.2 6.1 0.00019 21.2 6.1 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CEG40290.1 - 0.00024 20.8 1.0 0.013 15.3 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit PWI PF01480.17 CEG40290.1 - 0.0016 18.7 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-RING_6 PF14835.6 CEG40290.1 - 0.003 17.4 3.9 0.003 17.4 3.9 2.2 2 1 0 2 2 2 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 CEG40290.1 - 0.0088 16.0 0.5 0.019 14.9 0.5 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 CEG40290.1 - 0.011 15.7 0.5 0.027 14.5 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEG40290.1 - 2.6 7.9 10.5 0.2 11.4 4.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger OTCace_N PF02729.21 CEG40291.1 - 7.1e-44 149.4 0.0 2.8e-43 147.5 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CEG40291.1 - 8.2e-36 123.4 0.1 1.3e-35 122.8 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_M20 PF01546.28 CEG40292.1 - 2.3e-19 69.9 0.1 3.2e-16 59.7 0.2 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEG40292.1 - 6.7e-09 35.6 0.0 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain CENP-B_N PF04218.13 CEG40292.1 - 9.9e-06 25.1 0.9 2.4e-05 23.9 0.9 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CEG40292.1 - 0.00036 20.2 0.1 0.00076 19.2 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CEG40292.1 - 0.004 17.7 0.2 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 CEG40292.1 - 0.0078 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 CEG40292.1 - 0.0098 15.8 0.2 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 HTH domain HTH_37 PF13744.6 CEG40292.1 - 0.056 13.4 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 CEG40292.1 - 0.076 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Cyd_oper_YbgE PF09600.10 CEG40292.1 - 0.1 13.0 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Phage_antitermQ PF06530.12 CEG40292.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_AsnC-type PF13404.6 CEG40292.1 - 0.14 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain AbiEi_4 PF13338.6 CEG40292.1 - 0.16 12.1 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin GntR PF00392.21 CEG40292.1 - 0.16 11.6 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 CEG40292.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_10 PF04967.12 CEG40292.1 - 0.32 10.8 2.4 0.36 10.7 0.1 2.3 3 0 0 3 3 3 0 HTH DNA binding domain dCMP_cyt_deam_1 PF00383.23 CEG40293.1 - 3.3e-27 94.3 0.0 5.8e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEG40293.1 - 1.9e-14 53.6 0.1 5.9e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 MafB19-like deaminase APOBEC3 PF18771.1 CEG40293.1 - 0.032 14.4 0.2 0.071 13.2 0.2 1.6 1 0 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 CEG40293.1 - 0.041 14.0 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 OB_NTP_bind PF07717.16 CEG40295.1 - 0.046 14.1 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold TED PF08341.11 CEG40296.1 - 0.16 12.3 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioester domain DUF659 PF04937.15 CEG40297.1 - 3.7e-11 43.1 0.1 9.8e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CEG40297.1 - 1.1e-05 25.1 0.4 2.5e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CEG40297.1 - 0.0012 18.8 0.4 0.0027 17.7 0.4 1.6 1 0 0 1 1 1 1 BED zinc finger rhaM PF05336.13 CEG40297.1 - 0.05 13.7 1.5 0.15 12.1 0.1 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase fn3 PF00041.21 CEG40298.1 - 9e-11 42.0 4.9 4.4e-09 36.6 0.5 2.7 2 0 0 2 2 2 2 Fibronectin type III domain EF-hand_1 PF00036.32 CEG40298.1 - 6e-06 25.4 2.8 0.17 11.5 0.0 3.4 2 1 1 3 3 3 3 EF hand SAM_2 PF07647.17 CEG40298.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_7 PF13499.6 CEG40298.1 - 0.00015 22.2 5.3 0.0036 17.7 5.1 2.6 1 1 1 2 2 2 1 EF-hand domain pair SAM_1 PF00536.30 CEG40298.1 - 0.00015 22.1 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_6 PF13405.6 CEG40298.1 - 0.0002 21.0 3.4 6.2 7.0 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain fn3_4 PF16794.5 CEG40298.1 - 0.00024 20.9 0.7 0.00056 19.8 0.1 1.9 2 0 0 2 2 2 1 Fibronectin-III type domain EF-hand_8 PF13833.6 CEG40298.1 - 0.0054 16.6 1.6 0.85 9.5 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG40298.1 - 0.0071 15.8 2.9 13 5.5 0.0 3.3 3 0 0 3 3 3 1 EF hand SSP160 PF06933.11 CEG40298.1 - 0.0073 14.6 0.8 0.013 13.8 0.8 1.3 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Zip PF02535.22 CEG40299.1 - 5.4e-19 68.6 10.6 2.3e-18 66.5 10.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter LCCL PF03815.19 CEG40300.1 - 0.081 13.0 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 LCCL domain Pkinase PF00069.25 CEG40301.1 - 4e-68 229.6 0.0 6.7e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40301.1 - 1.5e-32 112.9 0.0 3e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40301.1 - 3.6e-05 23.2 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG40301.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain AAA PF00004.29 CEG40302.1 - 3.8e-43 147.1 0.1 9.3e-43 145.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG40302.1 - 2.3e-11 43.3 0.1 6.1e-11 41.9 0.1 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CEG40302.1 - 1.4e-07 31.6 0.0 4.9e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEG40302.1 - 2.1e-06 27.9 0.0 5.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CEG40302.1 - 4.4e-06 26.5 0.5 1e-05 25.4 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CEG40302.1 - 6.9e-06 26.5 0.0 0.00014 22.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEG40302.1 - 8.5e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG40302.1 - 0.00014 22.2 2.1 0.0079 16.5 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEG40302.1 - 0.0019 18.4 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG40302.1 - 0.0032 18.0 0.1 0.027 15.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CEG40302.1 - 0.0032 17.2 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CEG40302.1 - 0.0043 16.3 0.0 0.009 15.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain PhoH PF02562.16 CEG40302.1 - 0.0051 16.3 0.1 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.26 CEG40302.1 - 0.0054 16.4 0.1 0.059 13.1 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CEG40302.1 - 0.0065 15.9 0.1 0.018 14.5 0.1 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG40302.1 - 0.0065 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEG40302.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEG40302.1 - 0.011 15.5 0.1 0.07 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain RILP PF11461.8 CEG40302.1 - 0.016 15.4 1.7 0.035 14.3 1.7 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein RNA_helicase PF00910.22 CEG40302.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 CEG40302.1 - 0.018 13.8 0.1 0.68 8.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG40302.1 - 0.021 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CEG40302.1 - 0.023 13.8 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HR1 PF02185.16 CEG40302.1 - 0.023 14.8 3.3 0.068 13.3 3.3 1.8 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 CEG40302.1 - 0.032 13.3 0.0 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CEG40302.1 - 0.032 14.3 0.0 0.12 12.4 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CEG40302.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CEG40302.1 - 0.043 13.2 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 1 0 KaiC AAA_25 PF13481.6 CEG40302.1 - 0.069 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEG40302.1 - 0.073 12.8 0.2 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain TSC22 PF01166.18 CEG40302.1 - 0.073 13.4 0.9 0.2 12.0 0.9 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DASH_Dad2 PF08654.10 CEG40302.1 - 0.074 13.5 0.5 0.23 11.9 0.5 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad2 SlyX PF04102.12 CEG40302.1 - 0.082 13.5 2.8 0.35 11.5 2.8 2.1 1 0 0 1 1 1 0 SlyX Zeta_toxin PF06414.12 CEG40302.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CEG40302.1 - 0.13 12.6 0.3 0.49 10.7 0.1 2.1 3 0 0 3 3 1 0 AAA domain Tropomyosin PF00261.20 CEG40302.1 - 0.18 11.1 6.3 0.31 10.4 2.7 2.1 2 0 0 2 2 2 0 Tropomyosin MscS_porin PF12795.7 CEG40302.1 - 0.27 10.8 7.0 0.44 10.0 7.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SHQ1 PF04925.15 CEG40303.1 - 4.1e-57 192.6 0.4 7.8e-57 191.7 0.4 1.5 1 0 0 1 1 1 1 SHQ1 protein Peptidase_M29 PF02073.15 CEG40304.1 - 0.036 12.9 1.8 0.044 12.5 1.8 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) IQ PF00612.27 CEG40304.1 - 0.05 13.4 3.3 0.05 13.4 3.3 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif SprA-related PF12118.8 CEG40304.1 - 0.054 12.6 4.8 0.062 12.4 4.8 1.1 1 0 0 1 1 1 0 SprA-related family OmpH PF03938.14 CEG40304.1 - 0.16 12.3 11.0 0.2 12.0 11.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PIEZO PF15917.5 CEG40304.1 - 0.21 11.0 6.4 0.27 10.7 6.4 1.1 1 0 0 1 1 1 0 Piezo Utp12 PF04003.12 CEG40305.1 - 2.1e-18 66.6 3.6 2.1e-18 66.6 3.6 2.2 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.32 CEG40305.1 - 0.075 13.9 3.0 6.7 7.8 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat BRE1 PF08647.11 CEG40306.1 - 1.1e-08 35.1 4.6 1.1e-08 35.1 4.6 9.3 5 3 6 11 11 11 3 BRE1 E3 ubiquitin ligase VPS11_C PF12451.8 CEG40306.1 - 9.9 6.5 9.4 0.6 10.4 0.7 3.8 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal DnaJ_C PF01556.18 CEG40307.1 - 2.8e-37 128.1 0.1 3.7e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG40307.1 - 7.1e-25 86.9 4.6 1.3e-24 86.1 4.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEG40307.1 - 2.5e-13 50.2 16.7 5.1e-13 49.2 16.7 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEG40307.1 - 0.0012 18.7 16.8 0.032 14.2 5.1 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF573 PF04504.14 CEG40307.1 - 0.19 12.4 2.1 0.36 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF573 HypA PF01155.19 CEG40307.1 - 0.51 10.4 10.0 0.57 10.2 1.8 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABM PF03992.16 CEG40308.1 - 7.6e-11 42.0 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 CEG40308.1 - 0.0035 17.9 0.0 0.0042 17.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dehydratase_hem PF13816.6 CEG40308.1 - 0.077 12.4 0.0 0.089 12.2 0.0 1.0 1 0 0 1 1 1 0 Haem-containing dehydratase Globin PF00042.22 CEG40309.1 - 5.8e-08 33.3 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 CEG40309.1 - 1e-07 32.6 0.0 1.2e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEG40309.1 - 2.7e-06 27.6 0.1 6.4e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pkinase PF00069.25 CEG40315.1 - 6e-68 229.1 0.0 7.5e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40315.1 - 1.4e-30 106.5 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40315.1 - 6.6e-06 25.6 0.1 0.00017 21.0 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG40315.1 - 0.0033 16.4 0.6 0.0051 15.8 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CEG40315.1 - 0.065 12.6 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.21 CEG40315.1 - 0.077 13.4 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase AhpC-TSA PF00578.21 CEG40316.1 - 3e-46 156.4 0.0 1.9e-24 85.9 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CEG40316.1 - 1.4e-28 99.5 0.0 5.9e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA_2 PF13911.6 CEG40316.1 - 6e-05 23.1 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 CEG40316.1 - 0.0015 18.1 0.0 0.11 12.0 0.0 2.1 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF899) DUF3618 PF12277.8 CEG40316.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) zf-RING_2 PF13639.6 CEG40318.1 - 1.4e-11 44.5 11.7 3e-11 43.5 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 CEG40318.1 - 1.1e-09 38.3 0.1 2.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 CEG40318.1 - 3.2e-08 33.7 11.6 6.9e-08 32.7 11.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG40318.1 - 1.8e-07 30.9 6.8 1.8e-07 30.9 6.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG40318.1 - 3.4e-07 29.9 3.2 8.8e-07 28.6 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEG40318.1 - 6.1e-06 26.2 5.6 1.2e-05 25.2 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CEG40318.1 - 8.9e-06 25.7 8.7 2.5e-05 24.2 8.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CEG40318.1 - 1.2e-05 25.1 12.3 2.4e-05 24.1 11.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG40318.1 - 3.5e-05 23.6 7.6 6.7e-05 22.7 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG40318.1 - 0.00076 19.4 8.5 0.0017 18.3 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.7 CEG40318.1 - 0.079 13.1 7.5 0.28 11.3 7.5 2.0 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 CEG40318.1 - 0.19 11.6 11.1 0.12 12.3 8.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CEG40318.1 - 0.19 11.9 16.0 1.5 9.1 13.4 3.0 1 1 2 3 3 3 0 FANCL C-terminal domain Baculo_RING PF05883.11 CEG40318.1 - 0.2 11.6 1.2 0.42 10.6 1.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Peptidase_C1 PF00112.23 CEG40319.1 - 8.2e-61 205.9 3.3 2e-60 204.6 3.3 1.7 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CEG40319.1 - 5.2e-11 42.8 1.3 1.2e-10 41.6 1.3 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) ELYS PF13934.6 CEG40319.1 - 1.4e-08 35.0 3.1 3.5e-08 33.7 3.1 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly Terminase_1 PF03354.15 CEG40320.1 - 0.009 14.6 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 1 Phage Terminase LAGLIDADG_WhiA PF14527.6 CEG40320.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Beach PF02138.18 CEG40322.1 - 6.2e-117 389.9 0.0 9.5e-117 389.3 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CEG40322.1 - 4.5e-15 55.6 0.5 1e-13 51.2 0.2 3.4 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CEG40322.1 - 4.1e-12 46.4 18.2 0.00068 20.4 0.4 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40322.1 - 1.2e-08 35.1 0.5 0.76 10.1 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 CEG40323.1 - 6.4e-46 156.4 0.0 9.7e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CEG40323.1 - 1.4e-34 119.3 8.3 2.7e-34 118.4 8.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CEG40323.1 - 4.3e-24 84.6 0.0 8.3e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CEG40323.1 - 1.6e-22 79.3 0.0 3.7e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CEG40323.1 - 5.5e-06 26.4 0.3 2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEG40323.1 - 1.6e-05 25.2 0.0 3.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Septin PF00735.18 CEG40323.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Septin Ras PF00071.22 CEG40323.1 - 0.011 15.3 0.0 0.035 13.7 0.0 1.7 1 1 0 1 1 1 0 Ras family Roc PF08477.13 CEG40323.1 - 0.044 14.0 0.0 0.36 11.1 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 CEG40325.1 - 3.2e-15 56.9 0.1 3.2e-15 56.9 0.1 4.4 4 2 0 4 4 4 1 SET domain preSET_CXC PF18264.1 CEG40325.1 - 2.8e-10 40.5 16.3 2.8e-10 40.5 16.3 3.5 3 1 0 3 3 3 1 CXC domain PH PF00169.29 CEG40326.1 - 7.8e-07 29.6 0.0 3.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 PH domain LRR_4 PF12799.7 CEG40327.1 - 3.1e-13 49.7 0.4 2.1e-05 24.8 0.0 3.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG40327.1 - 2.5e-11 43.2 1.2 4.4e-05 23.2 0.2 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CEG40327.1 - 3.5e-09 36.4 4.8 1e-08 34.9 0.3 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CEG40327.1 - 0.003 17.5 2.4 22 5.4 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat Tobravirus_2B PF05271.11 CEG40327.1 - 0.0063 16.4 0.4 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Tobravirus 2B protein LRR_1 PF00560.33 CEG40327.1 - 0.026 15.0 4.5 73 4.5 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat DUF4645 PF15488.6 CEG40327.1 - 0.18 11.2 0.5 0.42 10.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Pox_A_type_inc PF04508.12 CEG40327.1 - 0.41 10.6 6.5 2.1 8.3 0.5 4.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HNF-1_N PF04814.13 CEG40328.1 - 2.1 8.9 4.7 2.1 8.9 0.1 2.1 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Frag1 PF10277.9 CEG40329.1 - 0.0035 16.9 0.8 0.0035 16.9 0.8 2.1 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family DoxX_2 PF13564.6 CEG40329.1 - 0.5 10.5 3.8 1.5 8.9 0.6 2.7 2 1 0 2 2 2 0 DoxX-like family KTI12 PF08433.10 CEG40330.1 - 1.1e-70 238.3 0.0 1.2e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CEG40330.1 - 2.3e-09 37.5 0.2 4.5e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG40330.1 - 2.8e-06 27.8 0.1 2.7e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEG40330.1 - 2.5e-05 24.3 0.0 7.6e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.20 CEG40330.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.6 CEG40330.1 - 0.00038 20.7 0.5 0.051 13.8 0.0 3.0 1 1 3 4 4 4 1 AAA domain AAA_18 PF13238.6 CEG40330.1 - 0.0019 18.7 0.0 0.0043 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 CEG40330.1 - 0.0022 17.3 0.3 0.11 11.7 0.3 2.2 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Thymidylate_kin PF02223.17 CEG40330.1 - 0.0055 16.4 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase FTR_C PF02741.15 CEG40330.1 - 0.012 15.6 0.2 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 FTR, proximal lobe ATPase_2 PF01637.18 CEG40330.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 CEG40330.1 - 0.015 14.6 0.1 0.24 10.7 0.1 2.2 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain SKI PF01202.22 CEG40330.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_17 PF13207.6 CEG40330.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG40330.1 - 0.03 14.6 0.1 0.074 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG40330.1 - 0.031 14.6 0.1 0.23 11.8 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CEG40330.1 - 0.035 14.2 0.2 0.11 12.6 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CEG40330.1 - 0.09 12.0 0.1 0.45 9.8 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin tRNA_lig_kinase PF08303.11 CEG40330.1 - 0.12 12.5 0.5 1 9.4 0.5 2.1 1 1 0 1 1 1 0 tRNA ligase kinase domain LRR_4 PF12799.7 CEG40332.1 - 0.00038 20.8 0.2 0.29 11.6 0.0 4.5 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 CEG40332.1 - 0.037 13.9 0.5 0.73 9.8 0.0 3.3 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 CEG40332.1 - 0.059 13.3 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 CEG40332.1 - 0.17 12.0 4.6 25 5.3 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat MREG PF15812.5 CEG40333.1 - 0.018 15.3 0.3 0.031 14.6 0.3 1.5 1 1 0 1 1 1 0 Melanoregulin DUF726 PF05277.12 CEG40335.1 - 3.1e-86 289.4 11.5 2.1e-73 247.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF3158 PF11358.8 CEG40335.1 - 0.096 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) GCR1_C PF12550.8 CEG40336.1 - 0.00017 21.8 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes FIBP PF05427.11 CEG40338.1 - 5.5e-52 177.3 0.0 5.2e-45 154.3 0.0 2.0 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) Tim17 PF02466.19 CEG40340.1 - 9.6e-12 45.3 2.6 1.3e-11 44.8 2.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family YueH PF14166.6 CEG40340.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 YueH-like protein DUF2512 PF10710.9 CEG40340.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) EF-hand_7 PF13499.6 CEG40341.1 - 1.3e-16 60.8 7.6 2.6e-08 34.2 0.4 4.4 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CEG40341.1 - 2.9e-14 51.5 3.8 0.00019 20.7 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CEG40341.1 - 5.7e-13 48.5 3.8 0.00015 21.5 0.0 5.0 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG40341.1 - 3.3e-12 45.3 8.0 0.0016 18.2 0.0 5.6 5 1 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CEG40341.1 - 3.3e-09 35.8 0.9 0.0039 16.6 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CEG40341.1 - 0.00039 20.3 0.9 0.15 12.0 0.1 4.1 2 2 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG40341.1 - 0.00081 19.7 0.0 0.021 15.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 CEG40341.1 - 0.0052 16.7 0.2 25 4.7 0.0 3.5 2 1 1 3 3 3 0 Caleosin related protein EFhand_Ca_insen PF08726.10 CEG40341.1 - 0.026 14.6 1.5 0.6 10.2 0.0 3.1 3 0 0 3 3 3 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 CEG40341.1 - 0.12 12.7 0.9 1.2 9.5 0.2 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TFIIIC_sub6 PF10419.9 CEG40342.1 - 2.8e-07 30.3 1.5 2.9e-07 30.2 0.1 1.7 2 1 0 2 2 2 1 TFIIIC subunit triple barrel domain Cwf_Cwc_15 PF04889.12 CEG40342.1 - 3.3 7.4 12.7 4.8 6.8 12.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 CEG40342.1 - 4.7 6.8 9.4 6.6 6.4 9.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) zf-CCCH PF00642.24 CEG40343.1 - 6.8e-17 60.9 14.5 2.4e-06 27.3 2.3 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEG40343.1 - 6.1e-15 55.9 10.4 0.0001 23.0 0.9 3.6 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 CEG40343.1 - 4.4e-13 48.7 19.2 2.7e-07 30.2 1.7 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEG40343.1 - 5.1e-13 48.6 24.7 3.8e-05 23.6 6.4 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_2 PF14608.6 CEG40343.1 - 8.7e-11 41.9 17.5 0.00023 21.5 0.3 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-B_box PF00643.24 CEG40343.1 - 2e-09 37.4 17.4 4.9e-07 29.8 5.6 2.6 2 0 0 2 2 2 2 B-box zinc finger PHD_2 PF13831.6 CEG40343.1 - 0.12 11.9 0.4 0.12 11.9 0.4 4.4 2 2 2 4 4 4 0 PHD-finger zf-CCCH_3 PF15663.5 CEG40343.1 - 0.62 10.3 0.0 0.62 10.3 0.0 4.0 4 1 0 4 4 4 0 Zinc-finger containing family C1_4 PF07975.12 CEG40343.1 - 0.74 10.1 19.8 2.8 8.3 11.7 3.1 1 1 1 2 2 2 0 TFIIH C1-like domain eIF-5_eIF-2B PF01873.17 CEG40344.1 - 1.4e-23 83.0 0.0 2.6e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 SR-25 PF10500.9 CEG40344.1 - 0.016 14.8 6.0 0.021 14.4 6.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ribosomal_L24 PF17136.4 CEG40345.1 - 6.5e-19 68.1 0.0 1.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CEG40345.1 - 2e-07 30.7 1.8 2e-07 30.7 1.8 1.9 2 0 0 2 2 2 1 KOW motif CRAL_TRIO PF00650.20 CEG40346.1 - 7.5e-26 90.7 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG40346.1 - 0.0053 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RNA_pol_3_Rpc31 PF11705.8 CEG40347.1 - 0.0089 16.3 11.4 0.93 9.7 11.4 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_polI_A34 PF08208.11 CEG40348.1 - 0.0011 19.2 1.2 0.0017 18.5 1.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 FliJ PF02050.16 CEG40350.1 - 0.015 15.5 7.7 0.015 15.5 7.7 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein Phage_Nu1 PF07471.12 CEG40350.1 - 0.015 15.1 1.4 0.046 13.5 0.1 2.2 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 TMF_TATA_bd PF12325.8 CEG40350.1 - 0.038 14.2 14.5 0.21 11.8 3.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DpnI_C PF17726.1 CEG40350.1 - 0.056 13.6 0.5 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Dam-replacing HTH domain DUF4140 PF13600.6 CEG40350.1 - 0.87 10.1 9.4 0.22 12.0 0.8 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 CEG40350.1 - 1.1 9.9 9.1 18 6.1 8.3 2.7 1 1 0 1 1 1 0 Initiation control protein YabA Mto2_bdg PF12808.7 CEG40350.1 - 1.2 9.5 6.7 1.1 9.6 0.3 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region V-ATPase_G_2 PF16999.5 CEG40350.1 - 1.7 9.1 13.6 0.13 12.7 6.5 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit TPR_20 PF14561.6 CEG40350.1 - 5.7 7.4 9.3 0.95 9.8 3.4 2.4 2 2 0 2 2 2 0 Tetratricopeptide repeat PRKG1_interact PF15898.5 CEG40350.1 - 8.1 7.4 15.0 3.4 8.6 5.6 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain BolA PF01722.18 CEG40351.1 - 7e-17 61.5 0.0 8.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Kinesin PF00225.23 CEG40352.1 - 9.2e-97 323.9 2.6 1.5e-96 323.3 2.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG40352.1 - 9.5e-25 87.3 0.8 3.1e-24 85.6 0.1 2.2 3 0 0 3 3 3 1 Microtubule binding PRKG1_interact PF15898.5 CEG40352.1 - 0.016 16.1 1.7 0.016 16.1 1.7 4.1 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 CEG40352.1 - 0.028 14.6 1.4 0.028 14.6 1.4 3.2 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 HMMR_N PF15905.5 CEG40352.1 - 0.07 12.6 13.6 0.05 13.1 8.6 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Zeta_toxin PF06414.12 CEG40352.1 - 0.1 11.8 0.3 17 4.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin 3-alpha PF03475.14 CEG40352.1 - 0.11 12.3 0.1 0.37 10.7 0.1 1.9 1 0 0 1 1 1 0 3-alpha domain SHE3 PF17078.5 CEG40352.1 - 0.16 11.7 11.1 0.06 13.1 4.7 3.2 3 1 0 3 3 3 0 SWI5-dependent HO expression protein 3 KASH_CCD PF14662.6 CEG40352.1 - 0.4 10.5 22.1 3.9 7.2 0.1 4.9 4 1 1 5 5 5 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 CEG40352.1 - 2.8 8.3 10.0 2.3 8.6 0.1 4.3 4 0 0 4 4 4 0 TSC-22/dip/bun family NmrA PF05368.13 CEG40353.1 - 1.8e-12 47.4 0.3 2e-05 24.3 0.4 4.2 4 1 0 4 4 4 3 NmrA-like family NAD_binding_10 PF13460.6 CEG40353.1 - 2.2e-12 47.2 0.1 1.2e-08 35.1 0.3 2.4 2 0 0 2 2 2 2 NAD(P)H-binding DXP_reductoisom PF02670.16 CEG40353.1 - 0.029 15.1 0.0 0.093 13.5 0.1 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase polyprenyl_synt PF00348.17 CEG40354.1 - 1.2e-64 217.8 0.0 1.6e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 CEG40354.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Zw10 PF06248.13 CEG40358.1 - 2.1e-41 142.1 11.3 3.3e-41 141.5 11.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Lsm_C PF14894.6 CEG40358.1 - 0.03 14.1 0.2 0.085 12.7 0.2 1.8 1 0 0 1 1 1 0 Lsm C-terminal ABC_membrane PF00664.23 CEG40359.1 - 0.36 10.4 2.7 4.5 6.8 4.7 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region Cellulase PF00150.18 CEG40360.1 - 1.4e-11 44.4 0.6 2.3e-11 43.7 0.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 CEG40360.1 - 2e-08 34.8 0.1 6.7e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 X8 domain AP_endonuc_2 PF01261.24 CEG40360.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF4633 PF15464.6 CEG40361.1 - 0.083 13.0 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) DUF5089 PF17002.5 CEG40361.1 - 0.1 12.5 5.6 0.12 12.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) MIS13 PF08202.11 CEG40361.1 - 0.19 11.0 2.9 0.23 10.7 2.9 1.0 1 0 0 1 1 1 0 Mis12-Mtw1 protein family WD40 PF00400.32 CEG40362.1 - 8.3e-14 51.8 7.7 0.0013 19.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40362.1 - 1.3e-07 31.8 0.1 0.075 13.3 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 CEG40362.1 - 4.7e-05 23.1 0.3 0.18 11.8 0.1 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.6 CEG40362.1 - 0.0012 19.3 0.0 3.1 8.4 0.0 3.5 4 0 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 CEG40362.1 - 0.032 13.8 0.1 1.2 8.7 0.0 2.7 1 1 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 CEG40362.1 - 0.036 12.7 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.11 CEG40362.1 - 0.15 11.7 2.6 3.7 7.2 0.0 3.5 2 2 1 3 3 3 0 TUP1-like enhancer of split THUMP PF02926.17 CEG40363.1 - 6.3e-15 55.5 4.0 9.7e-15 54.9 0.6 2.2 1 1 1 2 2 2 1 THUMP domain zf-DNL PF05180.12 CEG40363.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 DNL zinc finger Ribosomal_L29e PF01779.17 CEG40364.1 - 6.4e-20 71.2 11.0 6.4e-20 71.2 11.0 2.2 2 0 0 2 2 2 1 Ribosomal L29e protein family Clathrin_lg_ch PF01086.17 CEG40365.1 - 7e-13 49.2 9.7 1.1e-09 38.6 7.8 2.1 2 0 0 2 2 2 2 Clathrin light chain Glyco_hydro_7 PF00840.20 CEG40366.1 - 2.3e-196 652.7 7.7 2.6e-196 652.5 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Phage_T7_tail PF03906.14 CEG40366.1 - 0.11 12.1 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Phage T7 tail fibre protein Cellulase PF00150.18 CEG40367.1 - 4.7e-09 36.1 1.6 1.1e-08 34.9 1.6 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 CEG40367.1 - 6.8e-09 36.3 0.1 2.7e-08 34.4 0.1 2.1 1 0 0 1 1 1 1 X8 domain AP_endonuc_2 PF01261.24 CEG40367.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel IL17R_fnIII_D1 PF16556.5 CEG40367.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 MLD PF11647.8 CEG40369.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Membrane Localization Domain TB2_DP1_HVA22 PF03134.19 CEG40370.1 - 5e-24 84.0 4.1 9.6e-24 83.1 4.1 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HupE_UreJ_2 PF13795.6 CEG40371.1 - 0.0023 17.6 5.8 0.0052 16.5 0.3 2.9 2 1 1 3 3 3 1 HupE / UreJ protein Ac76 PF05814.11 CEG40371.1 - 0.025 14.6 0.3 0.098 12.7 0.1 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) MerE PF05052.12 CEG40371.1 - 0.043 13.7 0.7 0.043 13.7 0.7 2.2 2 0 0 2 2 2 0 MerE protein FAM176 PF14851.6 CEG40371.1 - 0.063 12.9 0.3 0.063 12.9 0.3 2.8 1 1 1 2 2 2 0 FAM176 family Nre_C PF04895.12 CEG40371.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal Nre, C-terminal LCD1 PF09798.9 CEG40371.1 - 0.082 11.4 7.8 0.11 11.0 6.1 1.8 2 0 0 2 2 2 0 DNA damage checkpoint protein FoP_duplication PF13865.6 CEG40372.1 - 7.8e-20 71.2 17.7 7.8e-20 71.2 17.7 2.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 bZIP_2 PF07716.15 CEG40373.1 - 0.00062 19.8 1.3 0.00062 19.8 1.3 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEG40373.1 - 0.0034 17.5 2.5 0.0034 17.5 2.5 2.3 2 0 0 2 2 2 1 bZIP transcription factor Rootletin PF15035.6 CEG40373.1 - 0.0037 17.3 0.6 0.0037 17.3 0.6 1.5 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion STIMATE PF12400.8 CEG40374.1 - 6.6e-37 126.8 12.8 6.6e-37 126.8 12.8 1.5 2 0 0 2 2 2 1 STIMATE family DUF996 PF06195.13 CEG40374.1 - 0.0024 18.2 1.5 0.0024 18.2 1.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF996) Wzy_C PF04932.15 CEG40374.1 - 0.78 9.4 5.0 0.27 10.9 1.4 2.0 2 0 0 2 2 2 0 O-Antigen ligase PHD PF00628.29 CEG40375.1 - 5.7e-28 96.6 134.0 1.1e-05 25.3 5.1 16.0 13 3 3 16 16 16 10 PHD-finger FYRN PF05964.14 CEG40375.1 - 1.1e-17 63.6 0.1 2.8e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 CEG40375.1 - 8.8e-17 62.0 0.0 6e-15 56.0 0.0 3.1 2 0 0 2 2 2 1 SET domain Bromodomain PF00439.25 CEG40375.1 - 1.4e-14 53.9 0.0 3.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 CEG40375.1 - 7.7e-08 32.5 5.7 7.7e-08 32.5 5.7 10.7 9 1 1 10 10 10 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG40375.1 - 5.4e-07 29.8 9.2 5.4e-07 29.8 9.2 9.8 8 1 1 9 9 9 2 PHD-zinc-finger like domain PWWP PF00855.17 CEG40375.1 - 0.0041 17.5 0.1 0.013 15.9 0.1 1.8 1 0 0 1 1 1 1 PWWP domain FYRC PF05965.14 CEG40375.1 - 0.14 12.3 0.0 0.65 10.2 0.0 2.2 1 1 0 1 1 1 0 F/Y rich C-terminus PPTA PF01239.22 CEG40376.1 - 1e-36 123.6 15.2 4e-09 35.9 0.2 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Glyco_hydro_48 PF02011.15 CEG40376.1 - 0.021 13.4 0.1 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 TPR_14 PF13428.6 CEG40376.1 - 0.022 15.5 0.5 55 5.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_8 PF08022.12 CEG40377.1 - 6.6e-22 77.7 0.0 2.2e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 CEG40377.1 - 5.6e-15 55.6 11.4 1.6e-14 54.1 11.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG40377.1 - 2.3e-13 50.5 0.0 8.5e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CEG40377.1 - 1.8e-05 25.3 0.0 0.003 18.2 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEG40377.1 - 0.0036 17.6 0.0 0.0075 16.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ferric_reduct PF01794.19 CEG40378.1 - 8.2e-14 51.8 11.3 8.2e-14 51.8 11.3 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG40378.1 - 6.8e-09 36.0 0.0 2.4e-08 34.2 0.0 2.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG40378.1 - 0.0092 16.1 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain DUF2231 PF09990.9 CEG40378.1 - 3.2 8.2 8.0 0.58 10.6 3.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF373 PF04123.13 CEG40378.1 - 3.6 6.9 8.4 5.9 6.2 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_30 PF02055.16 CEG40379.1 - 3.1e-103 345.4 2.9 4.1e-103 345.0 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CEG40379.1 - 1.4e-14 54.1 1.3 2.9e-14 53.0 1.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 CEG40379.1 - 0.0003 20.1 0.4 0.00056 19.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 Retrotran_gag_2 PF14223.6 CEG40381.1 - 5.2e-08 32.7 0.0 3.6e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type PSI_integrin PF17205.3 CEG40382.1 - 0.017 14.8 2.1 0.022 14.5 2.1 1.2 1 0 0 1 1 1 0 Integrin plexin domain Castor_Poll_mid PF06241.12 CEG40383.1 - 1.5e-28 98.8 0.0 4.9e-27 93.9 0.0 2.5 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 CEG40383.1 - 7.2e-05 22.5 0.1 0.00064 19.5 0.0 2.7 3 0 0 3 3 3 1 TrkA-C domain TPR_1 PF00515.28 CEG40384.1 - 4.8e-35 118.0 27.6 7.2e-07 28.8 0.3 9.9 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG40384.1 - 1.7e-33 112.0 24.8 4.2e-08 32.7 0.4 10.1 10 1 0 10 10 9 5 Tetratricopeptide repeat DnaJ PF00226.31 CEG40384.1 - 2.5e-23 81.9 3.9 2.5e-23 81.9 3.9 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 CEG40384.1 - 2.7e-23 81.4 16.9 7.1e-05 22.4 0.9 8.8 6 3 3 9 9 9 6 TPR repeat TPR_16 PF13432.6 CEG40384.1 - 2.2e-22 79.4 12.7 5.8e-06 26.9 0.2 7.2 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40384.1 - 2.4e-22 79.2 18.6 2.3e-06 28.0 0.1 7.2 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40384.1 - 1.9e-20 71.3 21.6 0.002 18.2 0.1 8.9 9 1 0 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG40384.1 - 7.9e-17 60.5 20.7 0.0029 18.3 0.1 9.5 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40384.1 - 1.4e-15 56.1 12.4 0.066 13.3 0.1 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40384.1 - 9e-14 50.8 16.3 6.6e-05 23.0 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG40384.1 - 9.9e-10 38.6 27.3 0.0076 16.5 2.6 7.3 6 3 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40384.1 - 3.8e-09 36.6 22.2 0.00024 21.3 0.2 5.6 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEG40384.1 - 9.8e-09 35.3 12.7 2.9e-06 27.3 0.2 5.4 3 1 3 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 CEG40384.1 - 3.7e-07 30.7 16.4 0.16 12.4 0.0 5.7 4 1 3 7 7 6 3 Bacterial transcriptional activator domain TPR_6 PF13174.6 CEG40384.1 - 3.7e-06 27.2 30.7 0.0051 17.4 0.3 8.4 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEG40384.1 - 0.00012 21.5 12.2 0.036 13.3 0.0 5.1 3 2 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG40384.1 - 0.00013 21.7 8.7 0.2 11.6 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CEG40384.1 - 0.00023 20.7 0.7 0.0057 16.1 0.1 2.7 2 1 1 3 3 3 1 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 CEG40384.1 - 0.00039 20.1 0.1 0.0011 18.5 0.1 1.8 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) SRP_TPR_like PF17004.5 CEG40384.1 - 0.001 19.1 13.6 0.0036 17.3 0.0 4.3 2 2 2 4 4 4 2 Putative TPR-like repeat DUF3856 PF12968.7 CEG40384.1 - 0.0018 18.3 4.2 0.71 9.9 0.2 5.3 5 1 0 5 5 5 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CEG40384.1 - 0.0046 17.0 8.8 0.058 13.5 0.2 4.8 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 CEG40384.1 - 0.013 16.0 9.2 28 5.7 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 CEG40384.1 - 0.018 15.1 20.4 0.66 10.1 0.3 7.5 5 2 3 8 8 8 0 MIT (microtubule interacting and transport) domain Peptidase_S10 PF00450.22 CEG40384.1 - 0.071 12.5 1.4 0.13 11.6 1.4 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase Mhr1 PF12829.7 CEG40384.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination DUF4192 PF13830.6 CEG40384.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) HemY_N PF07219.13 CEG40384.1 - 0.27 11.4 1.2 47 4.2 0.0 3.3 3 1 0 3 3 2 0 HemY protein N-terminus Com_YlbF PF06133.11 CEG40384.1 - 0.43 11.2 12.6 1.2 9.8 0.4 4.3 4 1 0 4 4 3 0 Control of competence regulator ComK, YlbF/YmcA Alkyl_sulf_dimr PF14863.6 CEG40384.1 - 0.71 10.3 10.2 2.3 8.7 0.2 5.0 3 1 2 6 6 5 0 Alkyl sulfatase dimerisation Wtap PF17098.5 CEG40384.1 - 3.3 7.6 6.8 3.6 7.5 1.1 2.6 1 1 0 2 2 2 0 WTAP/Mum2p family TLD PF07534.16 CEG40386.1 - 9.6e-34 116.6 1.0 1.9e-33 115.6 1.0 1.5 1 0 0 1 1 1 1 TLD PDZ PF00595.24 CEG40386.1 - 0.00022 21.5 0.0 0.0048 17.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CEG40386.1 - 0.0063 16.3 0.0 0.9 9.4 0.0 2.6 3 0 0 3 3 3 2 PDZ domain Mac PF12464.8 CEG40387.1 - 0.41 10.9 1.9 31 4.9 0.1 3.3 3 0 0 3 3 3 0 Maltose acetyltransferase Anoctamin PF04547.12 CEG40388.1 - 4.7e-125 417.9 15.5 6.6e-125 417.5 15.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.9 CEG40388.1 - 0.19 10.5 1.7 2.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Abhydrolase_9_N PF15420.6 CEG40388.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.8 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus DUF1772 PF08592.11 CEG40388.1 - 0.22 11.8 8.1 11 6.4 3.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) TRIQK PF15168.6 CEG40388.1 - 0.43 10.5 5.2 6.5 6.7 0.0 3.7 4 0 0 4 4 4 0 Triple QxxK/R motif-containing protein family Ninjurin PF04923.12 CEG40388.1 - 0.68 9.9 4.6 2.3 8.2 2.4 2.7 1 1 1 2 2 2 0 Ninjurin Pkinase PF00069.25 CEG40389.1 - 1.9e-63 214.3 0.0 3.3e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40389.1 - 3.1e-36 125.0 0.0 4.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40389.1 - 0.00077 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Ras PF00071.22 CEG40390.1 - 2.1e-61 206.3 0.1 2.4e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG40390.1 - 2.6e-33 114.8 0.0 4.4e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG40390.1 - 2.4e-13 49.9 0.0 2.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG40390.1 - 2.7e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG40390.1 - 0.00015 21.8 0.2 0.31 11.0 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG40390.1 - 0.00023 20.8 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEG40390.1 - 0.00027 20.4 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG40390.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEG40390.1 - 0.031 14.5 0.1 0.19 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CEG40390.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SWIB PF02201.18 CEG40391.1 - 2.2e-21 75.5 0.0 2.4e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF2236 PF09995.9 CEG40391.1 - 0.06 13.5 0.0 0.06 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DivIC PF04977.15 CEG40392.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Septum formation initiator FYVE PF01363.21 CEG40394.1 - 3.6e-18 65.5 6.2 3.6e-18 65.5 6.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger DUSP PF06337.12 CEG40394.1 - 6.1e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 DUSP domain U-box PF04564.15 CEG40394.1 - 0.0063 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 CEG40394.1 - 0.079 12.9 8.9 0.18 11.8 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_2 PF14445.6 CEG40394.1 - 0.087 13.0 2.7 0.24 11.6 2.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_UBOX PF13445.6 CEG40394.1 - 0.16 12.0 6.6 0.42 10.7 6.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Cupin_8 PF13621.6 CEG40395.1 - 7.5e-59 199.5 0.0 9.6e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEG40395.1 - 1.2e-05 25.0 3.1 0.0044 16.5 0.0 2.8 3 0 0 3 3 3 2 Cupin superfamily protein COPI_assoc PF08507.10 CEG40396.1 - 4.6e-14 52.6 6.3 5.7e-14 52.3 6.3 1.1 1 0 0 1 1 1 1 COPI associated protein NTP_transf_2 PF01909.23 CEG40397.1 - 1.4e-10 41.3 0.0 3.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEG40397.1 - 2.3e-06 27.7 0.0 5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CEG40397.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 CEG40397.1 - 0.019 15.2 0.0 0.065 13.4 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase beta palm ThrE PF06738.12 CEG40397.1 - 0.1 12.0 0.0 6.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Putative threonine/serine exporter E1-E2_ATPase PF00122.20 CEG40398.1 - 1.5e-20 73.5 0.1 3.2e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEG40398.1 - 1.7e-10 41.5 1.8 0.00066 20.0 0.0 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG40398.1 - 0.00014 21.4 0.0 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG40398.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase EMC3_TMCO1 PF01956.16 CEG40398.1 - 0.24 11.1 5.5 0.15 11.8 2.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like USP8_interact PF08941.10 CEG40398.1 - 3.7 7.3 8.0 1.1e+02 2.6 7.3 2.5 2 0 0 2 2 2 0 USP8 interacting CCDC-167 PF15188.6 CEG40401.1 - 0.07 13.5 0.9 0.07 13.5 0.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tup_N PF08581.10 CEG40401.1 - 0.17 12.2 4.4 9.9 6.5 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal PET117 PF15786.5 CEG40401.1 - 0.63 10.3 4.2 0.2 12.0 0.4 2.1 1 1 1 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Ku PF02735.16 CEG40410.1 - 2.9e-48 164.3 0.0 6.2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CEG40410.1 - 9.7e-24 84.3 0.2 2e-23 83.3 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CEG40410.1 - 7.4e-14 52.2 0.1 2.4e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 CEG40410.1 - 2.1e-06 27.3 0.1 4.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Phage_TAC_5 PF08890.11 CEG40410.1 - 0.038 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC Pkinase_Tyr PF07714.17 CEG40411.1 - 1.7e-10 40.6 0.0 4.9e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CEG40411.1 - 3.4e-10 39.7 0.0 1.1e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CEG40411.1 - 3.8e-08 32.9 0.9 0.11 12.8 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 CEG40411.1 - 1.1e-05 25.8 0.0 0.0054 17.1 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 CEG40411.1 - 0.00019 21.5 0.1 0.0047 17.0 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 CEG40411.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Adaptin_N PF01602.20 CEG40411.1 - 0.017 13.7 0.1 0.065 11.8 0.1 1.6 1 1 1 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.8 CEG40411.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 CLASP N terminal HEAT_EZ PF13513.6 CEG40411.1 - 0.098 13.2 0.1 18 6.0 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat YabA PF06156.13 CEG40413.1 - 0.0015 19.1 8.4 0.0018 18.9 0.3 3.0 3 1 0 3 3 3 1 Initiation control protein YabA HAP1_N PF04849.13 CEG40413.1 - 0.0028 16.9 9.6 0.009 15.2 9.6 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DivIC PF04977.15 CEG40413.1 - 0.0042 16.8 11.5 0.0044 16.8 2.1 3.2 3 0 0 3 3 3 1 Septum formation initiator DUF4201 PF13870.6 CEG40413.1 - 0.019 14.7 2.7 0.046 13.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ZapB PF06005.12 CEG40413.1 - 0.041 14.3 4.3 0.041 14.3 4.3 3.2 3 1 0 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 CEG40413.1 - 0.05 13.8 0.9 0.05 13.8 0.9 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF4763 PF15960.5 CEG40413.1 - 0.055 12.8 11.1 0.12 11.7 6.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) TSC22 PF01166.18 CEG40413.1 - 0.057 13.7 2.0 0.057 13.7 2.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Staphylokinase PF02821.16 CEG40413.1 - 0.1 13.1 0.9 1.4 9.3 0.3 2.5 2 1 0 2 2 2 0 Staphylokinase/Streptokinase family Atg14 PF10186.9 CEG40413.1 - 0.13 11.3 5.8 0.023 13.8 1.4 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 CEG40413.1 - 0.18 12.9 8.8 0.39 11.9 0.2 2.8 3 1 1 4 4 3 0 Protein SOGA Prefoldin PF02996.17 CEG40413.1 - 0.34 10.8 3.4 1.4 8.9 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit PikAIV_N PF18605.1 CEG40413.1 - 0.39 10.3 4.0 1.5 8.4 4.0 2.1 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain EspB_PE PF18625.1 CEG40413.1 - 0.48 10.9 3.2 0.47 11.0 1.0 2.1 2 0 0 2 2 1 0 ESX-1 secreted protein B PE domain TolA_bind_tri PF16331.5 CEG40413.1 - 0.66 10.1 11.2 0.12 12.5 5.0 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Syntaxin-6_N PF09177.11 CEG40413.1 - 1 10.0 7.7 0.31 11.6 0.9 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 CEG40413.1 - 1 9.5 8.7 2 8.5 2.6 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Nnf1 PF03980.14 CEG40413.1 - 1.3 9.5 8.7 0.13 12.6 1.5 2.7 3 0 0 3 3 3 0 Nnf1 K-box PF01486.17 CEG40413.1 - 1.4 9.1 8.4 0.12 12.5 1.2 2.7 2 1 1 3 3 3 0 K-box region FlaC_arch PF05377.11 CEG40413.1 - 1.6 9.1 6.5 2.1 8.8 1.4 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 CEG40413.1 - 1.7 8.6 7.3 0.18 11.7 1.9 2.2 3 0 0 3 3 1 0 Shugoshin N-terminal coiled-coil region PRKG1_interact PF15898.5 CEG40413.1 - 2.1 9.3 12.8 3.3 8.6 9.3 2.6 2 1 0 2 2 1 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 CEG40413.1 - 2.8 7.2 9.3 6.8 5.9 9.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CEG40413.1 - 5.9 7.6 8.8 8.4 7.1 2.1 3.3 2 1 0 2 2 2 0 SlyX Spc24 PF08286.11 CEG40413.1 - 6.2 7.1 8.7 0.68 10.2 0.7 2.8 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 DDRGK PF09756.9 CEG40413.1 - 7.7 6.1 9.1 0.27 10.8 3.1 1.6 2 0 0 2 2 1 0 DDRGK domain GerD PF17898.1 CEG40415.1 - 4 7.4 13.2 0.54 10.2 0.7 3.7 3 1 1 4 4 4 0 Spore germination GerD central core domain Herpes_UL6 PF01763.16 CEG40416.1 - 0.019 13.5 1.2 0.018 13.6 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Flu_B_NS1 PF02942.14 CEG40416.1 - 0.023 13.8 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) SKA2 PF16740.5 CEG40416.1 - 0.063 13.1 3.1 0.09 12.6 3.1 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FYVE PF01363.21 CEG40420.1 - 1.9e-07 31.1 4.6 5.1e-07 29.7 4.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 CEG40420.1 - 0.012 15.9 4.0 0.012 15.9 4.0 2.2 2 0 0 2 2 2 0 C1 domain IBR PF01485.21 CEG40420.1 - 0.039 14.2 2.0 0.17 12.2 2.0 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain START PF01852.19 CEG40420.1 - 0.087 12.2 0.3 0.35 10.2 0.3 1.9 1 1 1 2 2 2 0 START domain FYVE_2 PF02318.16 CEG40420.1 - 1.4 9.1 9.2 0.24 11.6 4.9 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_2 PF13639.6 CEG40420.1 - 2.1 8.7 8.0 8.8 6.8 8.1 2.2 1 1 0 1 1 1 0 Ring finger domain zf-B_box PF00643.24 CEG40420.1 - 3.6 7.8 9.8 0.92 9.7 5.2 2.4 2 0 0 2 2 2 0 B-box zinc finger C1_1 PF00130.22 CEG40420.1 - 4.6 7.2 9.6 2.1 8.3 5.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Collagen PF01391.18 CEG40425.1 - 6.6e-07 29.0 13.8 1.3e-06 28.0 13.8 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PIN_4 PF13638.6 CEG40425.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 PIN domain Tyrosinase PF00264.20 CEG40426.1 - 2.7e-12 47.5 0.0 5.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase Sulfate_transp PF00916.20 CEG40428.1 - 2.1e-19 69.6 16.1 3.3e-19 68.9 16.1 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CEG40428.1 - 2.5e-08 33.9 0.0 5.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CEG40428.1 - 4e-06 26.5 0.0 8.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain FHA PF00498.26 CEG40429.1 - 2e-13 50.5 0.2 2.2e-11 43.9 0.1 2.7 2 0 0 2 2 2 1 FHA domain RINGv PF12906.7 CEG40429.1 - 3.8e-13 49.3 6.4 1.4e-12 47.5 6.4 2.0 1 1 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 CEG40429.1 - 1.4e-06 28.6 0.0 4.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 CEG40429.1 - 0.0055 17.0 6.9 0.2 12.0 8.3 2.5 1 1 1 2 2 2 1 Ring finger domain PGA2 PF07543.12 CEG40435.1 - 0.13 12.3 11.0 0.08 12.9 7.2 2.2 1 1 0 2 2 2 0 Protein trafficking PGA2 CHD5 PF04420.14 CEG40435.1 - 0.15 11.9 0.4 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 CHD5-like protein SAPS PF04499.15 CEG40436.1 - 0.067 12.0 0.9 0.071 11.9 0.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 CEG40436.1 - 2.8 6.0 12.4 3.6 5.7 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 CEG40436.1 - 5.1 6.0 7.3 6.5 5.6 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CEG40436.1 - 8.7 5.4 4.9 11 5.1 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_16 PF13191.6 CEG40437.1 - 4.9e-05 23.8 0.0 8.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 CEG40437.1 - 0.018 14.1 0.0 0.064 12.3 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 CEG40437.1 - 0.02 15.4 0.0 0.06 13.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEG40437.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CEG40437.1 - 0.027 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 CEG40437.1 - 0.032 14.7 0.3 0.11 13.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 CEG40437.1 - 0.054 13.8 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEG40437.1 - 0.063 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CEG40437.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CEG40437.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 CEG40437.1 - 0.1 11.7 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 CEG40437.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 CEG40437.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CEG40437.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.7 CEG40437.1 - 0.19 11.2 1.3 0.32 10.5 1.3 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_30 PF13604.6 CEG40437.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_coat_N PF08398.10 CEG40438.1 - 0.04 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 PSP PF04046.16 CEG40439.1 - 0.09 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 PSP TGase_elicitor PF16683.5 CEG40441.1 - 1.6e-92 310.1 0.5 5.5e-92 308.3 0.5 1.7 1 1 0 1 1 1 1 Transglutaminase elicitor DUF4642 PF15484.6 CEG40442.1 - 0.022 15.0 3.3 0.033 14.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) CDC45 PF02724.14 CEG40442.1 - 5 5.3 10.1 6.1 5.0 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RVT_2 PF07727.14 CEG40444.1 - 4.4e-43 147.7 1.6 4.8e-43 147.5 1.6 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG40444.1 - 0.006 16.1 0.2 0.0091 15.5 0.2 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toxin_R_bind_N PF07953.12 CEG40444.1 - 0.088 12.5 0.2 0.86 9.3 0.1 1.9 1 1 1 2 2 2 0 Clostridium neurotoxin, N-terminal receptor binding Sec10 PF07393.11 CEG40445.1 - 2.1e-67 228.1 9.4 3e-67 227.6 9.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 EzrA PF06160.12 CEG40445.1 - 0.015 13.5 0.1 0.16 10.1 0.0 2.4 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Fer2_4 PF13510.6 CEG40445.1 - 0.063 13.3 0.0 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2183 PF09949.9 CEG40446.1 - 0.002 18.4 0.1 0.016 15.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF2207 PF09972.9 CEG40446.1 - 9.9 4.8 7.7 19 3.8 7.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.22 CEG40452.1 - 1.2e-77 261.7 0.0 1.5e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5457 PF17540.2 CEG40453.1 - 0.035 14.2 0.0 0.16 12.1 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5457) LEM PF03020.15 CEG40453.1 - 0.067 12.8 0.4 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 LEM domain DUF3103 PF11301.8 CEG40453.1 - 0.078 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Gemini_C4 PF01492.17 CEG40453.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Geminivirus C4 protein SHIPPO-rpt PF07004.12 CEG40456.1 - 0.39 11.7 0.2 0.39 11.7 0.2 4.0 5 0 0 5 5 5 0 Sperm-tail PG-rich repeat Pkinase PF00069.25 CEG40457.1 - 9e-72 241.6 0.0 1.4e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40457.1 - 5.8e-39 133.9 0.0 4.2e-38 131.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40457.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEG40457.1 - 0.00018 21.2 0.1 0.0068 16.1 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEG40457.1 - 0.002 18.1 0.1 0.063 13.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 CEG40459.1 - 1.4e-46 159.0 0.0 1.9e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40459.1 - 2.9e-27 95.6 0.0 4.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40459.1 - 4.5e-06 26.2 0.2 0.012 14.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CEG40459.1 - 0.00051 18.9 0.0 0.0013 17.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG40459.1 - 0.01 15.8 2.8 0.082 12.8 0.4 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG40459.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 CEG40460.1 - 0.00031 20.7 0.1 0.00049 20.0 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.12 CEG40460.1 - 0.005 17.3 1.5 0.0086 16.5 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM52 PF14979.6 CEG40460.1 - 0.0081 16.1 0.4 0.017 15.0 0.4 1.5 1 0 0 1 1 1 1 Transmembrane 52 LYRIC PF15686.5 CEG40460.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Peptidase_M56 PF05569.11 CEG40460.1 - 0.038 13.2 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 PRIMA1 PF16101.5 CEG40460.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.9 3 1 0 3 3 3 0 Proline-rich membrane anchor 1 TMEM132D_C PF15706.5 CEG40460.1 - 0.092 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Baculo_11_kDa PF06143.11 CEG40460.1 - 0.15 11.6 2.1 0.11 12.1 0.6 1.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family Orf78 PF06024.12 CEG40460.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Pkinase PF00069.25 CEG40461.1 - 4e-52 177.2 0.0 4.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40461.1 - 1.2e-33 116.5 0.0 1.9e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG40461.1 - 0.00064 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG40461.1 - 0.0016 18.4 0.2 0.0038 17.2 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG40461.1 - 0.0054 15.7 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG40461.1 - 0.0055 15.5 0.1 0.0081 15.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CEG40461.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GRASP55_65 PF04495.14 CEG40462.1 - 6.1e-57 191.8 0.0 1.4e-42 145.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CEG40462.1 - 1.2e-07 32.0 0.0 0.0076 16.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CEG40462.1 - 8.6e-06 25.5 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CEG40462.1 - 0.091 13.1 0.0 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain HTH_ParB PF17762.1 CEG40464.1 - 0.071 12.9 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 HTH domain found in ParB protein DUF3246 PF11596.8 CEG40468.1 - 0.0064 16.0 5.5 0.0083 15.6 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) LuxE PF04443.12 CEG40469.1 - 0.031 13.3 0.1 0.035 13.1 0.1 1.0 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE WH2 PF02205.20 CEG40469.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 WH2 motif Spore_III_AB PF09548.10 CEG40469.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) UPF0258 PF06789.12 CEG40469.1 - 0.11 12.6 1.4 0.18 11.9 1.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) SNARE PF05739.19 CEG40469.1 - 2.2 8.3 9.1 11 6.1 9.1 2.2 1 1 0 1 1 1 0 SNARE domain Surfac_D-trimer PF09006.11 CEG40470.1 - 0.027 14.4 0.0 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Mito_carr PF00153.27 CEG40471.1 - 3.6e-65 215.9 2.2 6.8e-21 74.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CKS PF01111.19 CEG40472.1 - 5.1e-35 119.6 1.0 6.5e-35 119.2 1.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Dynein_light PF01221.18 CEG40473.1 - 8.8e-27 93.3 1.8 1e-26 93.0 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 tRNA-synt_2 PF00152.20 CEG40474.1 - 4.4e-82 275.7 0.0 5.3e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEG40474.1 - 6.6e-09 35.6 0.3 1.8e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEG40474.1 - 0.041 13.4 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) MAPEG PF01124.18 CEG40475.1 - 1.7e-13 50.6 0.3 2.2e-13 50.2 0.3 1.2 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 CEG40476.1 - 3.3e-11 43.2 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 MAPEG family DUF4790 PF16037.5 CEG40480.1 - 0.032 14.7 0.4 0.032 14.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4790) MCRA PF06100.11 CEG40480.1 - 0.069 11.9 0.1 0.085 11.6 0.1 1.2 1 0 0 1 1 1 0 MCRA family LKAAEAR PF15478.6 CEG40480.1 - 2.5 8.4 14.2 2.2 8.5 12.9 1.6 1 1 0 1 1 1 0 Family of unknown function with LKAAEAR motif T7SS_ESX_EspC PF10824.8 CEG40481.1 - 0.31 11.5 8.8 0.072 13.6 3.0 2.7 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm CALCOCO1 PF07888.11 CEG40481.1 - 1.1 8.0 43.7 5.4 5.8 42.4 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 CEG40481.1 - 4 7.8 19.6 1.8 8.9 0.1 3.8 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.18 CEG40481.1 - 5 7.5 17.9 0.5 10.7 0.1 4.9 4 1 0 4 4 4 0 TSC-22/dip/bun family ACR_tran PF00873.19 CEG40481.1 - 6.3 4.3 5.9 8.8 3.8 5.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family APG6_N PF17675.1 CEG40481.1 - 8.4 6.9 48.6 4.3 7.9 18.3 4.0 1 1 2 3 3 3 0 Apg6 coiled-coil region KH_1 PF00013.29 CEG40482.1 - 2e-37 126.8 0.8 3.1e-11 42.9 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CEG40482.1 - 0.033 14.1 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 KH domain Cadherin-like PF12733.7 CEG40485.1 - 0.25 11.9 2.4 7.6 7.1 0.2 2.4 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain Retrotran_gag_2 PF14223.6 CEG40486.1 - 6.2e-09 35.6 0.2 8.4e-09 35.2 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3284 PF11687.8 CEG40486.1 - 0.0037 17.1 0.5 0.0062 16.4 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3284) Pkinase_Tyr PF07714.17 CEG40487.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CK2S PF15011.6 CEG40493.1 - 0.011 15.7 0.2 0.013 15.4 0.2 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate SlyX PF04102.12 CEG40493.1 - 0.048 14.3 0.3 0.066 13.8 0.3 1.3 1 1 0 1 1 1 0 SlyX Ribosomal_L4 PF00573.22 CEG40500.1 - 0.053 13.2 1.0 0.064 12.9 1.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family GFO_IDH_MocA PF01408.22 CEG40502.1 - 8.9e-09 36.2 5.8 0.00015 22.6 0.4 3.1 2 1 1 3 3 3 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEG40502.1 - 6.3e-08 32.6 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 CEG40502.1 - 0.0025 18.4 1.1 0.0047 17.5 0.4 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 CEG40502.1 - 0.0043 16.9 0.2 0.0079 16.1 0.2 1.4 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 CEG40502.1 - 0.0048 16.5 0.1 0.009 15.6 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 CEG40502.1 - 0.013 15.4 0.3 0.02 14.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEG40502.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SURF2 PF05477.11 CEG40503.1 - 3e-22 79.5 0.3 3e-22 79.5 0.3 2.0 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) Aha1_N PF09229.11 CEG40504.1 - 4.6e-22 78.7 0.0 9.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_2 PF07719.17 CEG40504.1 - 2.2e-06 27.3 0.1 5e-05 23.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40504.1 - 1.2e-05 24.9 0.1 0.00015 21.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40504.1 - 2.6e-05 24.6 0.5 7e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40504.1 - 0.0006 19.8 0.2 0.0023 18.0 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40504.1 - 0.0043 17.7 0.2 0.0043 17.7 0.2 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40504.1 - 0.0077 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CEG40504.1 - 0.0088 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CEG40504.1 - 0.01 15.5 0.1 0.3 10.8 0.0 2.4 1 1 1 2 2 2 0 TPR repeat TPR_14 PF13428.6 CEG40504.1 - 0.015 16.1 0.7 0.076 13.9 0.0 2.5 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40504.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.8 CEG40504.1 - 0.13 11.1 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 CEG40504.1 - 0.16 12.7 0.0 0.43 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEG40504.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat HIG_1_N PF04588.13 CEG40505.1 - 7.8e-15 54.8 0.2 1.1e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Dynamin_M PF01031.20 CEG40506.1 - 2.8e-110 368.0 0.0 1.7e-109 365.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CEG40506.1 - 2.2e-59 200.3 0.1 3.8e-59 199.5 0.1 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CEG40506.1 - 2.3e-27 95.0 1.2 5.6e-27 93.7 1.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEG40506.1 - 0.0001 22.4 0.7 0.00089 19.3 0.7 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CEG40506.1 - 0.031 14.0 0.4 0.26 11.0 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 CEG40506.1 - 0.084 12.4 0.3 6.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 CEG40506.1 - 0.16 12.4 0.0 0.82 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF2431 PF10354.9 CEG40507.1 - 6.9e-42 143.6 0.0 9.1e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Nuc_deoxyri_tr3 PF11071.8 CEG40507.1 - 0.14 12.2 0.3 0.62 10.1 0.2 2.0 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ Cas6_N PF17952.1 CEG40507.1 - 0.2 11.9 2.6 1.7 9.0 0.3 2.5 2 0 0 2 2 2 0 Cas6 N-terminal domain BK_channel_a PF03493.18 CEG40508.1 - 5e-24 84.3 0.1 3.2e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CEG40508.1 - 1.8e-11 43.9 8.3 1.8e-11 43.9 8.3 2.4 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 CEG40508.1 - 7.1e-05 22.1 14.4 7.1e-05 22.1 14.4 1.6 1 1 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 CEG40508.1 - 0.018 15.3 1.0 0.5 10.6 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain DUF4501 PF14946.6 CEG40508.1 - 0.071 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Lig_chan PF00060.26 CEG40508.1 - 0.093 12.6 3.9 0.099 12.5 1.0 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel SIT PF15330.6 CEG40508.1 - 0.15 12.5 0.4 6.8 7.2 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT IRK PF01007.20 CEG40508.1 - 0.54 10.1 2.9 0.64 9.8 0.8 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Hat1_N PF10394.9 CEG40509.1 - 4.4e-31 108.3 0.0 7e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CEG40509.1 - 0.027 14.7 0.0 0.13 12.5 0.0 1.9 1 1 0 2 2 2 0 Acetyltransferase (GNAT) family Polyoma_agno PF01736.16 CEG40509.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein Pkinase PF00069.25 CEG40510.1 - 2.3e-65 220.6 0.0 2.4e-64 217.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain eIF-6 PF01912.18 CEG40510.1 - 1.4e-61 207.3 0.1 3e-61 206.3 0.1 1.5 1 0 0 1 1 1 1 eIF-6 family Pkinase_Tyr PF07714.17 CEG40510.1 - 1e-49 169.2 0.0 4.5e-49 167.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.14 CEG40511.1 - 2.3 6.4 10.2 3 6.0 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein AMP-binding PF00501.28 CEG40512.1 - 8.7e-40 136.6 0.0 1.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEG40512.1 - 0.0019 19.1 0.0 0.0036 18.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sec20 PF03908.13 CEG40513.1 - 5.3e-12 45.5 1.7 5e-11 42.4 0.2 2.3 2 1 0 2 2 2 1 Sec20 YqjK PF13997.6 CEG40513.1 - 0.028 14.6 4.4 2.4 8.5 0.0 3.5 3 0 0 3 3 3 0 YqjK-like protein RasGAP_C PF03836.15 CEG40513.1 - 0.2 11.8 10.0 0.9 9.7 0.5 2.5 1 1 1 2 2 2 0 RasGAP C-terminus V-SNARE_C PF12352.8 CEG40513.1 - 0.28 11.5 3.9 0.15 12.4 0.5 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Snf7 PF03357.21 CEG40513.1 - 0.3 10.7 8.0 0.72 9.4 8.0 1.8 1 1 0 1 1 1 0 Snf7 Prok-TraM PF09228.10 CEG40513.1 - 0.41 11.1 6.0 0.12 12.8 1.7 2.2 1 1 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Osteopontin PF00865.18 CEG40513.1 - 3.9 6.9 10.2 0.1 12.0 1.8 2.0 1 1 1 2 2 2 0 Osteopontin ALO PF04030.14 CEG40515.1 - 5.3e-22 78.9 1.9 5.5e-21 75.5 1.6 2.4 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CEG40515.1 - 1.3e-14 54.1 0.2 6.8e-14 51.8 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain DLH PF01738.18 CEG40515.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF4489 PF14879.6 CEG40518.1 - 0.046 13.8 0.0 0.053 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) RRM_1 PF00076.22 CEG40519.1 - 7.8e-21 73.7 0.1 1.3e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CEG40519.1 - 1.6e-16 60.7 2.6 1.6e-16 60.7 2.6 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Glyco_transf_24 PF18404.1 CEG40520.1 - 1.3e-137 457.6 2.0 2.2e-137 456.8 2.0 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CEG40520.1 - 2.3e-35 122.8 2.1 4.3e-30 105.5 0.1 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CEG40520.1 - 9.1e-29 100.7 0.0 2e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CEG40520.1 - 5e-24 84.5 0.0 1.4e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 CEG40520.1 - 1.9e-23 82.9 0.9 1.9e-23 82.9 0.9 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CEG40520.1 - 1.8e-06 27.7 0.1 3.5e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 CEG40520.1 - 0.00048 20.1 1.1 0.29 11.0 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like domain NOA36 PF06524.12 CEG40521.1 - 0.0042 16.5 11.0 0.0056 16.1 9.8 1.7 2 0 0 2 2 2 1 NOA36 protein Cwf_Cwc_15 PF04889.12 CEG40521.1 - 0.0099 15.6 8.5 0.011 15.5 8.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 CEG40521.1 - 0.025 14.6 3.4 0.028 14.5 3.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CEG40521.1 - 0.12 10.5 10.7 0.12 10.4 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Importin_rep_6 PF18829.1 CEG40521.1 - 0.24 11.6 6.3 0.25 11.5 5.2 1.6 2 0 0 2 2 2 0 Importin repeat 6 DUF4611 PF15387.6 CEG40521.1 - 0.32 11.2 7.2 0.41 10.9 6.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Rhabdo_ncap PF00945.18 CEG40521.1 - 0.81 8.5 4.6 0.84 8.5 4.6 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2457 PF10446.9 CEG40521.1 - 1.4 7.9 18.3 1.7 7.7 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 CEG40521.1 - 1.7 6.9 7.1 1.9 6.6 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CEG40521.1 - 2.1 8.0 5.7 2.8 7.6 5.7 1.2 1 0 0 1 1 1 0 FAM176 family DUF2076 PF09849.9 CEG40521.1 - 2.1 8.3 10.8 2.4 8.1 10.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CENP-B_dimeris PF09026.10 CEG40521.1 - 3.6 8.0 22.8 5.9 7.4 22.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ANAPC15 PF15243.6 CEG40521.1 - 3.6 8.0 13.5 5.2 7.5 13.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RRN3 PF05327.11 CEG40521.1 - 3.9 5.9 6.8 4.1 5.8 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Thiolase_N PF00108.23 CEG40522.1 - 2.2e-84 282.9 0.3 4.5e-83 278.6 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEG40522.1 - 1.1e-48 163.9 3.1 2.9e-48 162.6 0.3 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEG40522.1 - 0.00096 18.8 5.1 0.013 15.1 0.2 3.4 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Dimer_Tnp_hAT PF05699.14 CEG40523.1 - 8.7e-12 44.7 0.0 3.2e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CEG40523.1 - 3.6e-05 23.7 1.3 6.9e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_4 PF13894.6 CEG40523.1 - 0.045 14.6 1.3 0.14 13.0 1.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4413 PF14372.6 CEG40523.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) HTH_psq PF05225.16 CEG40524.1 - 0.093 12.5 0.8 14 5.5 0.1 2.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Gasdermin_C PF17708.1 CEG40524.1 - 0.23 11.6 13.8 0.14 12.3 3.0 3.2 1 1 1 3 3 3 0 Gasdermin PUB domain Mtc PF03820.17 CEG40525.1 - 1.8e-79 267.0 0.0 1.9e-47 161.9 0.0 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier DUF5375 PF17345.2 CEG40525.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5375) AAA_26 PF13500.6 CEG40526.1 - 4.8e-23 82.0 0.0 8.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RT_RNaseH_2 PF17919.1 CEG40527.1 - 0.051 13.6 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase nec1 PF10379.9 CEG40529.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Virulence protein nec1 HAGH_C PF16123.5 CEG40531.1 - 6.4e-26 90.7 0.0 1.2e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEG40531.1 - 1.6e-08 34.8 0.5 1.1e-07 32.0 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEG40531.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Foie-gras_1 PF11817.8 CEG40532.1 - 4.6e-18 65.7 5.8 3.4e-17 62.9 5.8 2.2 1 1 0 1 1 1 1 Foie gras liver health family 1 HR1 PF02185.16 CEG40532.1 - 0.12 12.5 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Hr1 repeat TrmO PF01980.16 CEG40534.1 - 1.7e-41 141.1 0.0 4.1e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 CEG40534.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 TrmO C-terminal domain Pkinase PF00069.25 CEG40536.1 - 2.5e-76 256.5 0.0 3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40536.1 - 5.8e-35 120.8 0.0 6.8e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40536.1 - 2.8e-11 43.3 0.0 5.5e-11 42.3 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG40536.1 - 3.8e-06 25.9 0.0 5.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG40536.1 - 1.2e-05 24.7 0.1 1.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG40536.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEG40536.1 - 0.18 11.4 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA_11 PF13086.6 CEG40537.1 - 1.4e-66 225.0 4.2 4.9e-33 115.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 CEG40537.1 - 1.7e-62 210.6 0.0 3e-62 209.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEG40537.1 - 4.4e-12 46.1 0.3 1.6e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CEG40537.1 - 2.5e-09 37.2 0.3 0.1 12.3 0.0 4.3 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEG40537.1 - 9e-09 35.8 0.5 0.00047 20.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEG40537.1 - 7.6e-06 26.2 0.0 9.6e-05 22.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 CEG40537.1 - 0.00095 18.3 0.1 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 CEG40537.1 - 0.0026 17.8 0.0 0.47 10.4 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.29 CEG40537.1 - 0.0043 17.5 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 CEG40537.1 - 0.0077 15.8 2.4 1.9 8.0 0.1 2.9 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CEG40537.1 - 0.011 16.1 0.0 0.064 13.6 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEG40537.1 - 0.015 14.6 0.3 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 CEG40537.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CEG40537.1 - 0.039 13.3 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CEG40537.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CEG40537.1 - 0.13 12.8 0.0 0.47 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEG40537.1 - 0.16 11.9 0.1 2.2 8.1 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Chorein_N PF12624.7 CEG40538.1 - 4.4e-09 36.5 0.2 2.3e-08 34.2 0.1 2.2 1 1 1 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CEG40538.1 - 5.8e-05 23.0 11.8 0.0011 18.8 10.5 2.6 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Clat_adaptor_s PF01217.20 CEG40539.1 - 4.2e-37 127.3 1.3 4.7e-37 127.1 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 CEG40539.1 - 0.21 12.3 2.1 0.55 10.9 1.3 2.2 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox PAH PF02671.21 CEG40540.1 - 0.065 13.4 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat PolyA_pol PF01743.20 CEG40542.1 - 1.8e-13 51.0 0.1 5.9e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 CEG40542.1 - 1.4e-08 34.8 0.0 3.6e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative Ribosomal_L23 PF00276.20 CEG40544.1 - 5.5e-17 61.9 2.0 5.5e-17 61.9 2.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CEG40544.1 - 1.4e-14 54.0 6.1 3.2e-14 52.8 6.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain YihI PF04220.12 CEG40544.1 - 0.022 14.5 0.3 0.026 14.2 0.3 1.3 1 1 0 1 1 1 0 Der GTPase activator (YihI) PTH2 PF01981.16 CEG40545.1 - 7.1e-46 155.3 0.4 9.7e-46 154.9 0.4 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Metallophos PF00149.28 CEG40546.1 - 4.6e-09 37.1 1.7 9.5e-09 36.0 1.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG40546.1 - 0.033 14.4 0.2 0.065 13.4 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain IRK_C PF17655.1 CEG40547.1 - 7.4e-30 103.8 3.0 3.6e-13 49.5 0.0 3.6 3 0 0 3 3 3 3 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CEG40547.1 - 1.2e-13 51.1 24.1 5.3e-06 26.3 8.6 3.9 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CEG40547.1 - 5.8e-12 45.4 22.1 3.5e-06 26.9 7.9 2.4 2 0 0 2 2 2 2 Ion channel Integrase_H2C2 PF17921.1 CEG40552.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Integrase zinc binding domain Glyco_hydro_53 PF07745.13 CEG40553.1 - 5.8e-60 203.1 0.0 7.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.8 CEG40553.1 - 0.039 13.5 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core DUF416 PF04222.12 CEG40553.1 - 0.048 13.1 0.1 0.083 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Uma2 PF05685.12 CEG40554.1 - 2.4e-09 37.0 0.1 3.6e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease zf-C2H2_4 PF13894.6 CEG40554.1 - 0.055 14.3 0.8 0.23 12.4 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 CEG40558.1 - 1.5e-10 40.9 0.1 1.9e-09 37.3 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CEG40558.1 - 3.9e-06 25.9 0.1 6.4e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEG40558.1 - 0.00038 19.8 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG40558.1 - 0.76 9.6 5.7 0.12 12.3 1.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tudor_4 PF18358.1 CEG40559.1 - 0.033 13.8 0.7 0.63 9.7 0.1 3.0 4 0 0 4 4 4 0 Histone methyltransferase Tudor domain Uma2 PF05685.12 CEG40560.1 - 0.00053 19.6 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative restriction endonuclease Tau95 PF09734.9 CEG40561.1 - 4.5e-25 89.1 1.5 7.7e-25 88.3 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CEG40561.1 - 1.1e-18 67.7 0.0 3e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Tau95 Triple barrel domain Pkinase PF00069.25 CEG40562.1 - 2.4e-67 227.1 0.0 2.9e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40562.1 - 4.3e-33 114.7 0.0 5.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40562.1 - 3.5e-05 23.3 0.0 7.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CEG40562.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 CEG40562.1 - 0.02 15.6 0.1 0.058 14.1 0.1 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 CEG40562.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PqqD PF05402.12 CEG40562.1 - 0.04 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Pkinase_fungal PF17667.1 CEG40562.1 - 0.052 12.3 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CEG40565.1 - 4.7e-39 134.4 0.0 8.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40565.1 - 1.9e-25 89.7 0.0 3.3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG40565.1 - 3.5e-10 40.3 0.0 1.7e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 PH domain Kdo PF06293.14 CEG40565.1 - 6.8e-06 25.6 0.0 2.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEG40565.1 - 0.025 14.1 0.0 0.56 9.7 0.0 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.23 CEG40565.1 - 0.039 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG40565.1 - 0.1 11.9 0.0 5.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.32 CEG40566.1 - 1.6e-40 136.3 24.7 6.8e-08 33.1 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat zf-CCHC_2 PF13696.6 CEG40566.1 - 3.2e-27 93.9 26.9 1.5e-10 40.7 2.2 3.5 3 0 0 3 3 3 3 Zinc knuckle ANAPC4_WD40 PF12894.7 CEG40566.1 - 4.7e-16 58.9 6.1 0.00087 19.5 0.1 6.3 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.23 CEG40566.1 - 4.7e-12 45.4 20.0 0.0005 20.0 4.0 3.6 3 0 0 3 3 3 3 Zinc knuckle eIF2A PF08662.11 CEG40566.1 - 9.4e-09 35.4 1.5 0.044 13.7 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A zf-CCHC_3 PF13917.6 CEG40566.1 - 2.1e-05 24.4 15.8 0.026 14.5 0.3 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 CEG40566.1 - 0.0007 19.2 13.4 0.1 12.3 0.2 3.5 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger Nucleoporin_N PF08801.11 CEG40566.1 - 0.016 14.0 0.0 0.81 8.4 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Usp PF00582.26 CEG40567.1 - 2.6e-07 31.2 0.4 0.00012 22.7 0.2 3.4 3 1 0 3 3 3 2 Universal stress protein family Oxidored_q6 PF01058.22 CEG40568.1 - 2.4e-23 82.4 0.1 3.4e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 CEG40568.1 - 0.031 14.1 0.5 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Honey bee peptides MMR_HSR1 PF01926.23 CEG40570.1 - 6.8e-10 39.0 0.0 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG40570.1 - 5.4e-06 26.1 0.2 0.11 12.1 0.0 3.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEG40570.1 - 3.8e-05 23.7 0.1 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 CEG40570.1 - 0.0025 17.2 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 Septin Ras PF00071.22 CEG40570.1 - 0.0036 16.9 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CEG40570.1 - 0.0041 17.3 0.1 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CEG40570.1 - 0.0044 17.1 3.2 0.064 13.3 2.1 2.7 2 1 0 2 2 2 1 Dynamin family PduV-EutP PF10662.9 CEG40570.1 - 0.011 15.5 0.0 0.054 13.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Spore_IV_A PF09547.10 CEG40570.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) FeoB_N PF02421.18 CEG40570.1 - 0.03 13.8 0.7 2.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B RNA_helicase PF00910.22 CEG40570.1 - 0.035 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CEG40570.1 - 0.072 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 CEG40570.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CEG40570.1 - 0.091 11.7 0.0 4.2 6.3 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 CEG40570.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ski_Sno PF02437.17 CEG40571.1 - 0.00076 19.2 0.1 0.00099 18.8 0.1 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family FAT PF02259.23 CEG40573.1 - 7.8e-36 124.0 9.0 7.8e-36 124.0 9.0 2.9 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 CEG40573.1 - 5.5e-24 85.3 0.3 7.4e-23 81.6 0.0 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEG40573.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 FATC domain GRIP PF01465.20 CEG40574.1 - 2e-15 56.4 0.0 5.1e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 GRIP domain PH PF00169.29 CEG40575.1 - 9.8e-51 170.7 3.9 1.2e-09 38.6 0.1 8.4 8 0 0 8 8 8 8 PH domain PH_11 PF15413.6 CEG40575.1 - 3.7e-07 30.5 9.9 1.5 9.3 0.1 7.6 7 3 0 7 7 7 3 Pleckstrin homology domain PDZ PF00595.24 CEG40575.1 - 6.1e-07 29.7 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG40575.1 - 2.3e-06 27.3 0.1 2.2e-05 24.2 0.0 2.5 3 0 0 3 3 3 1 PDZ domain PH_BEACH PF14844.6 CEG40575.1 - 0.043 13.9 0.2 0.52 10.4 0.2 2.7 3 0 0 3 3 3 0 PH domain associated with Beige/BEACH PH_10 PF15411.6 CEG40575.1 - 0.15 12.3 0.9 37 4.6 0.0 3.7 3 0 0 3 3 3 0 Pleckstrin homology domain PH_12 PF16457.5 CEG40575.1 - 1.5 9.3 5.8 37 4.9 0.0 4.4 4 1 1 5 5 5 0 Pleckstrin homology domain TRAPP PF04051.16 CEG40581.1 - 7.9e-36 123.0 0.1 9.2e-36 122.8 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TraS PF10624.9 CEG40583.1 - 1.6 8.6 4.7 1.9 8.4 0.5 2.5 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Beach PF02138.18 CEG40584.1 - 3.7e-113 377.5 0.0 6.3e-113 376.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CEG40584.1 - 1.5e-12 47.4 0.3 2.6e-11 43.5 0.2 2.8 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CEG40584.1 - 2.2e-11 44.1 14.0 0.0013 19.5 0.0 5.6 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40584.1 - 1.8e-07 31.3 0.0 2 8.8 0.0 5.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 CEG40584.1 - 0.00033 20.5 0.0 0.00098 19.0 0.0 1.8 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 CEG40584.1 - 0.00082 19.7 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Ge1_WD40 PF16529.5 CEG40584.1 - 0.0014 17.7 0.0 0.012 14.6 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CEG40584.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Retrotran_gag_2 PF14223.6 CEG40585.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG40585.1 - 0.023 14.8 1.1 0.061 13.4 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 CEG40588.1 - 1.2e-49 168.4 0.6 4.7e-49 166.5 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG40588.1 - 4e-29 101.2 0.1 4.1e-27 94.7 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DNase_II PF03265.15 CEG40588.1 - 1.6e-14 53.9 2.4 1.7e-13 50.6 0.1 3.5 2 1 0 2 2 2 1 Deoxyribonuclease II UBA_3 PF09288.10 CEG40588.1 - 0.12 12.3 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Eapp_C PF10238.9 CEG40588.1 - 0.14 12.3 1.6 0.4 10.8 1.6 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein SAPS PF04499.15 CEG40589.1 - 1.7e-20 73.3 2.0 5.4e-15 55.2 0.1 5.0 4 1 1 5 5 5 3 SIT4 phosphatase-associated protein ABC_membrane PF00664.23 CEG40590.1 - 2.1e-96 322.8 20.4 1.2e-50 172.7 12.7 3.0 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG40590.1 - 5.8e-73 243.8 0.4 7.9e-36 123.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CEG40590.1 - 9.6e-15 54.6 0.1 2.2e-06 27.3 0.0 3.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CEG40590.1 - 1.1e-07 32.0 0.0 0.0032 17.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 CEG40590.1 - 3.6e-07 29.3 4.7 0.0019 17.0 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CEG40590.1 - 2.1e-06 28.1 1.2 0.06 13.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CEG40590.1 - 9.3e-06 25.3 0.1 0.047 13.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 CEG40590.1 - 4e-05 24.0 5.1 0.1 13.0 0.2 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG40590.1 - 0.00029 21.3 0.2 0.95 9.8 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CEG40590.1 - 0.0006 19.8 2.7 0.48 10.4 0.1 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CEG40590.1 - 0.0007 19.8 3.0 2.1 8.7 0.3 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 CEG40590.1 - 0.0018 18.6 0.2 0.75 10.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG40590.1 - 0.0019 17.8 1.6 3.8 7.0 0.1 3.6 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.20 CEG40590.1 - 0.0043 17.0 0.1 0.61 10.0 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_7 PF12775.7 CEG40590.1 - 0.005 16.4 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CEG40590.1 - 0.005 16.6 0.7 2.3 7.9 0.4 3.8 3 2 0 3 3 3 1 AAA domain MoaE PF02391.17 CEG40590.1 - 0.0065 16.7 2.7 0.71 10.2 0.4 2.9 2 0 0 2 2 2 1 MoaE protein AAA_15 PF13175.6 CEG40590.1 - 0.014 15.1 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 CEG40590.1 - 0.015 15.1 0.8 1.6 8.4 0.2 3.4 3 1 0 3 3 3 0 DEAD/DEAH box helicase DUF87 PF01935.17 CEG40590.1 - 0.036 14.1 0.4 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 CEG40590.1 - 0.038 14.2 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG40590.1 - 0.045 14.3 1.9 16 6.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 CEG40590.1 - 0.069 12.9 2.4 9.1 6.0 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein G-alpha PF00503.20 CEG40590.1 - 0.11 11.6 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Dala_Dala_lig_N PF01820.21 CEG40590.1 - 0.15 12.6 0.1 12 6.4 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_6 PF12774.7 CEG40591.1 - 4.1e-121 403.9 0.0 4.5e-102 341.4 0.0 4.0 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG40591.1 - 3.9e-97 325.9 4.1 3.9e-97 325.9 4.1 5.6 5 1 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CEG40591.1 - 6.6e-70 234.7 0.1 2e-68 229.8 0.0 3.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CEG40591.1 - 2.3e-49 168.1 0.0 3.9e-48 164.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 CEG40591.1 - 3.4e-37 127.5 0.0 1.7e-22 79.9 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CEG40591.1 - 9.3e-37 126.4 0.0 2.3e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DHC_N1 PF08385.12 CEG40591.1 - 7e-35 120.7 7.0 7e-35 120.7 7.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 CEG40591.1 - 2e-33 115.0 0.0 4e-31 107.6 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CEG40591.1 - 7e-30 104.3 0.2 2.2e-29 102.7 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CEG40591.1 - 1.3e-28 99.7 3.9 1.1e-25 90.2 0.0 3.8 4 0 0 4 4 3 2 P-loop containing dynein motor region MT PF12777.7 CEG40591.1 - 2.6e-28 99.1 7.2 5.2e-28 98.1 7.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 CEG40591.1 - 1.8e-06 28.3 6.7 0.81 10.0 0.0 5.9 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.6 CEG40591.1 - 3.6e-06 27.5 24.4 0.073 13.5 0.0 10.0 8 2 0 8 8 6 1 AAA ATPase domain AAA PF00004.29 CEG40591.1 - 1.2e-05 25.8 0.9 0.35 11.3 0.0 5.1 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEG40591.1 - 3e-05 24.0 5.6 0.062 13.2 0.0 4.9 5 0 0 5 5 5 2 RsgA GTPase AAA_24 PF13479.6 CEG40591.1 - 0.00018 21.3 0.0 0.16 11.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CEG40591.1 - 0.00029 21.1 0.0 0.57 10.4 0.0 4.5 5 0 0 5 5 3 1 AAA domain IstB_IS21 PF01695.17 CEG40591.1 - 0.00031 20.5 0.3 0.91 9.2 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 CEG40591.1 - 0.00072 19.3 0.0 0.36 10.6 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CEG40591.1 - 0.0015 18.7 4.2 2.4 8.3 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 CEG40591.1 - 0.0018 18.0 0.2 1.2 8.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CEG40591.1 - 0.0033 18.0 0.9 0.87 10.1 0.0 4.7 5 0 0 5 5 3 1 AAA domain Guanylate_kin PF00625.21 CEG40591.1 - 0.023 14.4 0.1 0.88 9.2 0.0 2.8 2 0 0 2 2 2 0 Guanylate kinase RNA_helicase PF00910.22 CEG40591.1 - 0.03 14.7 0.1 5.6 7.4 0.0 3.3 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 CEG40591.1 - 0.042 13.8 4.1 0.13 12.1 0.0 3.4 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CEG40591.1 - 0.051 13.3 0.1 20 4.8 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 CEG40591.1 - 0.064 12.8 0.0 11 5.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEG40591.1 - 0.13 11.8 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CEG40591.1 - 0.22 12.1 0.0 0.22 12.1 0.0 5.0 6 0 0 6 6 2 0 ABC transporter Alanine_zipper PF11839.8 CEG40591.1 - 0.23 11.8 8.0 2.2 8.7 8.0 2.9 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Sugarporin_N PF11471.8 CEG40591.1 - 6.9 6.7 9.9 1.3 9.1 0.0 3.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Synthase_beta PF11421.8 CEG40596.1 - 0.019 15.7 1.7 0.046 14.4 1.7 1.8 1 1 0 1 1 1 0 ATP synthase F1 beta subunit Ribophorin_I PF04597.14 CEG40597.1 - 4.3e-129 431.5 1.0 5e-129 431.3 1.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L12 PF00542.19 CEG40598.1 - 1.1e-26 92.9 10.1 2.5e-26 91.8 10.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CEG40598.1 - 6.3e-09 35.4 0.2 6.3e-09 35.4 0.2 3.3 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF2551 PF10826.8 CEG40598.1 - 0.092 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF3072 PF11272.8 CEG40598.1 - 0.68 9.9 3.3 1.8 8.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) RVT_2 PF07727.14 CEG40599.1 - 0.0083 15.8 0.0 2.5 7.7 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Antimicrobial12 PF08107.11 CEG40599.1 - 0.046 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Pleurocidin family Myotub-related PF06602.14 CEG40603.1 - 1.1e-113 379.8 0.1 2.1e-113 378.9 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Vps36_ESCRT-II PF11605.8 CEG40603.1 - 0.004 17.3 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DSPc PF00782.20 CEG40603.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain VPS13_C PF16909.5 CEG40603.1 - 0.12 12.2 3.8 0.23 11.2 3.8 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal UPF0176_N PF17773.1 CEG40604.1 - 6.9e-21 74.4 0.1 2.5e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CEG40604.1 - 2.7e-12 46.9 8.6 9.8e-12 45.1 8.6 2.0 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 CEG40604.1 - 6.1e-10 39.6 0.1 1.7e-09 38.1 0.1 1.9 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 CEG40604.1 - 0.01 15.9 11.3 0.087 13.0 0.5 2.7 2 0 0 2 2 2 0 FYVE zinc finger Cortex-I_coil PF09304.10 CEG40604.1 - 0.24 11.6 7.8 0.31 11.3 3.1 2.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil zf-P11 PF03854.14 CEG40604.1 - 0.53 10.0 7.5 0.032 13.9 1.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger HydF_tetramer PF18133.1 CEG40606.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain zf-C2H2 PF00096.26 CEG40611.1 - 2e-07 31.0 5.5 0.0011 19.3 1.4 3.1 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CEG40611.1 - 4.2e-07 29.8 3.1 0.007 16.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CEG40611.1 - 9.9e-06 26.0 11.5 0.0067 17.2 1.1 3.5 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEG40611.1 - 4.8e-05 23.0 4.8 0.015 15.0 1.1 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 CEG40611.1 - 0.00085 19.2 5.6 0.085 12.8 1.7 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 CEG40611.1 - 0.0028 18.0 1.8 0.67 10.4 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CEG40611.1 - 0.019 14.6 2.0 11 5.7 0.0 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HrpB2 PF09487.10 CEG40611.1 - 0.061 13.8 0.0 0.24 11.9 0.0 2.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) zf-BED PF02892.15 CEG40611.1 - 0.078 13.0 1.8 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 CEG40611.1 - 0.08 13.3 12.0 1.6 9.1 0.0 4.1 2 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) YhfH PF14149.6 CEG40611.1 - 0.22 11.6 2.2 17 5.5 0.0 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-C2HE PF16278.5 CEG40611.1 - 0.24 11.9 1.8 24 5.5 0.2 3.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 CEG40611.1 - 0.54 10.4 10.5 4.9 7.4 0.7 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) CpXC PF14353.6 CEG40611.1 - 0.56 10.3 2.9 6.7 6.8 1.1 3.2 2 1 1 3 3 3 0 CpXC protein zf-C2H2_jaz PF12171.8 CEG40611.1 - 0.57 10.5 2.8 5.3 7.4 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CEG40611.1 - 3.6 7.8 7.2 43 4.3 0.0 3.8 1 1 1 2 2 2 0 Zinc ribbon domain PKcGMP_CC PF16808.5 CEG40611.1 - 4.8 7.1 6.1 1.5 8.7 0.1 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MRP-S26 PF14943.6 CEG40611.1 - 8.7 6.2 10.0 3.3 7.6 0.7 2.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PH PF00169.29 CEG40616.1 - 5.3e-06 26.9 0.0 8.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PH domain TatD_DNase PF01026.21 CEG40617.1 - 9.1e-55 185.8 0.0 1.1e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Frataxin_Cyay PF01491.16 CEG40620.1 - 3.6e-32 110.7 0.0 3.9e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain SNF5 PF04855.12 CEG40621.1 - 1.9e-25 90.1 1.0 2e-15 57.3 0.0 2.6 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 HMG_box PF00505.19 CEG40621.1 - 3.8e-08 33.6 0.1 8.9e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEG40621.1 - 0.042 14.5 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain Pro_isomerase PF00160.21 CEG40623.1 - 1.9e-37 129.0 0.1 2.5e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ycf70 PF17382.2 CEG40623.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Ycf70-like AAA PF00004.29 CEG40624.1 - 3.9e-72 240.9 0.0 1.3e-36 126.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG40624.1 - 4.9e-26 90.3 3.0 7.9e-17 60.8 0.1 3.0 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEG40624.1 - 1.4e-11 45.1 3.3 0.00051 20.5 0.0 4.0 2 1 1 3 3 3 3 AAA ATPase domain AAA_2 PF07724.14 CEG40624.1 - 2.2e-10 40.9 0.0 5.2e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEG40624.1 - 3.5e-07 30.3 0.3 0.04 13.9 0.1 4.1 4 2 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG40624.1 - 1.1e-05 25.8 0.7 0.0011 19.2 0.2 3.6 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CEG40624.1 - 1.3e-05 25.0 0.0 0.091 12.5 0.0 3.5 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CEG40624.1 - 0.0001 21.8 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CEG40624.1 - 0.00011 22.4 0.1 0.032 14.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain Rad17 PF03215.15 CEG40624.1 - 0.00033 20.6 0.1 0.16 11.9 0.0 2.8 2 2 0 2 2 2 1 Rad17 P-loop domain DUF815 PF05673.13 CEG40624.1 - 0.00057 19.1 0.1 0.25 10.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CEG40624.1 - 0.0013 18.1 0.1 0.069 12.3 0.0 2.5 2 1 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 CEG40624.1 - 0.0035 17.7 0.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 CEG40624.1 - 0.0049 16.9 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CEG40624.1 - 0.012 15.3 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEG40624.1 - 0.014 14.8 0.2 1 8.7 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CEG40624.1 - 0.017 15.7 0.0 0.49 10.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 CEG40624.1 - 0.023 15.1 0.6 0.29 11.5 0.1 2.9 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 CEG40624.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CEG40624.1 - 0.025 14.2 0.6 5.7 6.5 0.0 3.3 2 2 2 4 4 4 0 AAA domain TsaE PF02367.17 CEG40624.1 - 0.042 13.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CEG40624.1 - 0.051 13.4 0.0 4.1 7.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CEG40624.1 - 0.053 13.4 0.1 0.51 10.2 0.0 2.5 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.6 CEG40624.1 - 0.067 13.2 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Vps4_C PF09336.10 CEG40624.1 - 0.091 12.8 0.0 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain MCM PF00493.23 CEG40624.1 - 0.098 11.7 0.0 18 4.3 0.0 2.7 3 0 0 3 3 3 0 MCM P-loop domain NB-ARC PF00931.22 CEG40624.1 - 0.1 11.8 0.0 0.81 8.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.11 CEG40624.1 - 0.11 12.4 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CEG40624.1 - 0.11 12.2 0.0 3.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CEG40624.1 - 0.15 12.6 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 ABC transporter TFIIE-A_C PF11521.8 CEG40625.1 - 0.76 10.1 4.8 1 9.7 4.8 1.5 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Nop14 PF04147.12 CEG40625.1 - 0.86 7.7 4.0 0.95 7.6 4.0 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 CEG40625.1 - 2.6 7.3 6.7 2.9 7.1 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 CEG40625.1 - 6.5 6.4 7.1 7.4 6.2 7.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDP-OH_P_transf PF01066.21 CEG40626.1 - 9.7e-16 58.3 0.1 9.7e-16 58.3 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TPR_2 PF07719.17 CEG40627.1 - 5e-21 73.1 7.8 2.2e-05 24.2 0.4 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40627.1 - 6.4e-20 70.1 9.2 1.2e-06 28.0 0.7 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG40627.1 - 6.5e-17 60.8 3.4 0.012 16.4 0.0 6.8 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40627.1 - 1.1e-15 56.4 4.7 0.0019 18.3 0.2 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40627.1 - 1.5e-15 57.6 3.5 0.00012 22.7 0.4 3.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40627.1 - 6e-14 52.3 3.8 2.4e-05 24.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40627.1 - 1.8e-13 49.9 10.1 0.00011 21.8 0.1 5.3 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 CEG40627.1 - 6.2e-12 45.0 5.4 0.017 15.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40627.1 - 3.3e-09 36.8 1.1 0.0028 17.8 0.2 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG40627.1 - 3.5e-09 36.8 2.4 0.024 14.9 1.5 4.5 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40627.1 - 8.6e-09 34.8 1.2 0.00073 19.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG40627.1 - 0.00014 22.3 0.0 38 5.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3921 PF13060.6 CEG40627.1 - 0.0076 16.3 0.1 0.55 10.3 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3921) TPR_20 PF14561.6 CEG40627.1 - 0.014 15.7 5.4 1.2 9.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40627.1 - 0.024 14.9 2.9 0.14 12.4 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEG40627.1 - 0.045 13.6 2.6 0.22 11.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 CEG40627.1 - 0.68 10.4 3.6 56 4.1 0.1 3.7 4 0 0 4 4 3 0 Bacterial transcriptional activator domain ZZ PF00569.17 CEG40630.1 - 9.6e-06 25.3 2.1 2.3e-05 24.1 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type LemA PF04011.12 CEG40630.1 - 0.0028 17.5 0.5 0.006 16.5 0.5 1.5 1 0 0 1 1 1 1 LemA family ABC_tran_CTD PF16326.5 CEG40630.1 - 0.007 16.6 0.7 0.02 15.1 0.7 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF3287 PF11690.8 CEG40630.1 - 0.49 10.1 2.5 0.6 9.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) ATG16 PF08614.11 CEG40630.1 - 0.71 10.1 5.5 0.14 12.3 1.8 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DnaJ_CXXCXGXG PF00684.19 CEG40630.1 - 4.8 7.6 8.2 3.5 8.1 4.6 2.5 2 1 1 3 3 3 0 DnaJ central domain Asp PF00026.23 CEG40631.1 - 1.7e-30 106.6 0.3 1.1e-28 100.7 0.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG40631.1 - 0.00052 20.3 0.7 0.072 13.3 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG40631.1 - 0.0014 18.4 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal MtN3_slv PF03083.16 CEG40633.1 - 3.9e-31 106.9 14.4 4.6e-20 71.4 2.4 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CEG40633.1 - 0.00015 21.4 0.8 0.00015 21.4 0.8 3.1 2 1 1 3 3 3 1 PQ loop repeat EbsA PF17255.2 CEG40633.1 - 0.072 13.4 0.3 0.22 11.9 0.3 1.9 1 0 0 1 1 1 0 EbsA-like protein MASE5 PF17178.4 CEG40633.1 - 3.7 7.4 13.2 0.074 12.9 4.5 2.2 1 1 2 3 3 3 0 Membrane-associated sensor MtN3_slv PF03083.16 CEG40634.1 - 4.3e-28 97.2 15.3 7.3e-18 64.4 5.5 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CEG40634.1 - 0.019 14.7 0.3 0.019 14.7 0.3 3.3 3 1 0 4 4 4 0 PQ loop repeat OppC_N PF12911.7 CEG40634.1 - 0.053 13.5 1.5 0.16 12.0 0.9 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C CSN4_RPN5_eIF3a PF18420.1 CEG40639.1 - 0.063 13.4 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Gln_amidase PF15644.6 CEG40640.1 - 0.094 13.7 0.6 0.25 12.4 0.4 1.7 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase Raptor_N PF14538.6 CEG40643.1 - 6.4e-66 220.8 0.0 1.3e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CEG40643.1 - 5.4e-14 51.1 3.0 0.00076 19.5 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat WD40 PF00400.32 CEG40643.1 - 4e-13 49.6 0.8 0.6 11.1 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat HEAT_EZ PF13513.6 CEG40643.1 - 1.2e-08 35.2 0.3 0.00023 21.6 0.0 3.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 CEG40643.1 - 1e-07 32.2 0.3 0.00048 20.5 0.0 3.7 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.7 CEG40643.1 - 3.7e-06 27.1 0.0 0.0013 18.8 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 CEG40643.1 - 6e-06 26.5 0.0 2.4 8.5 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain UNC45-central PF11701.8 CEG40643.1 - 0.0011 19.0 0.1 1 9.3 0.0 2.9 2 1 1 3 3 3 2 Myosin-binding striated muscle assembly central Adaptin_N PF01602.20 CEG40643.1 - 0.13 10.8 0.0 2.4 6.6 0.0 2.2 1 1 0 2 2 2 0 Adaptin N terminal region Tctex-1 PF03645.13 CEG40644.1 - 4e-29 100.9 0.9 4.6e-29 100.7 0.9 1.0 1 0 0 1 1 1 1 Tctex-1 family PIP5K PF01504.18 CEG40645.1 - 1.1e-57 195.3 0.0 1.8e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.32 CEG40646.1 - 1.6e-27 95.2 6.9 3.6e-07 30.8 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40646.1 - 1.8e-16 60.2 0.1 6.6e-05 23.1 0.0 4.9 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CEG40646.1 - 2.3e-09 36.3 0.1 0.0027 16.3 0.0 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 CEG40646.1 - 1.3e-05 24.7 0.0 0.093 12.0 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 CEG40646.1 - 0.0035 16.5 0.2 3.2 6.7 0.0 2.9 2 1 0 2 2 2 2 Coatomer WD associated region Peptidase_S9_N PF02897.15 CEG40646.1 - 0.036 12.9 0.0 0.99 8.1 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain nsp9 PF08710.10 CEG40646.1 - 0.053 13.9 0.0 2.6 8.5 0.0 2.4 1 1 1 2 2 2 0 nsp9 replicase DUF1848 PF08902.11 CEG40647.1 - 0.065 12.9 0.1 0.065 12.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) UBA2_C PF16195.5 CEG40648.1 - 0.06 14.0 1.6 0.11 13.2 1.6 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF4636 PF15468.6 CEG40649.1 - 0.066 12.9 1.1 0.095 12.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) SPACA7 PF15307.6 CEG40649.1 - 2.4 8.4 7.5 0.25 11.6 0.9 2.3 2 1 1 3 3 3 0 Sperm acrosome-associated protein 7 RNase_PH PF01138.21 CEG40652.1 - 5.2e-31 107.9 0.1 9.2e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG40652.1 - 2.2e-06 27.6 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CNRIP1 PF15043.6 CEG40652.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 TCR PF03638.15 CEG40653.1 - 3.9e-18 65.5 53.7 6e-12 45.7 22.9 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 CEG40653.1 - 1.9 8.7 44.8 5.1 7.3 17.0 2.7 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Pkinase PF00069.25 CEG40654.1 - 3.6e-61 206.8 0.1 1.2e-60 205.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40654.1 - 6.6e-30 104.3 0.1 9.2e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG40654.1 - 3.2e-06 26.7 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG40654.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family 5_nucleotid PF05761.14 CEG40654.1 - 0.0031 16.5 0.2 0.0048 15.8 0.2 1.2 1 0 0 1 1 1 1 5' nucleotidase family APH PF01636.23 CEG40654.1 - 0.054 13.4 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ATPase-GT PF10640.9 CEG40654.1 - 0.089 11.6 0.1 1.2 7.9 0.0 2.1 1 1 0 2 2 2 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase Peptidase_M32 PF02074.15 CEG40656.1 - 0.038 12.8 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DIL PF01843.19 CEG40656.1 - 0.11 12.8 1.1 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 DIL domain SymE_toxin PF08845.10 CEG40663.1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system RecX PF02631.16 CEG40665.1 - 9.9e-06 26.0 0.0 0.067 13.6 0.0 3.4 3 1 0 3 3 3 2 RecX family tRNA_NucTran2_2 PF13735.6 CEG40665.1 - 0.003 17.6 0.4 0.22 11.5 0.0 3.1 3 0 0 3 3 3 1 tRNA nucleotidyltransferase domain 2 putative Death PF00531.22 CEG40665.1 - 0.003 17.7 2.2 0.099 12.8 0.3 3.3 3 0 0 3 3 3 1 Death domain Phycoerythr_ab PF02972.14 CEG40665.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain TetR_C_20 PF17925.1 CEG40665.1 - 0.16 12.3 0.1 26 5.2 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 CEG40667.1 - 8e-93 307.8 0.0 2.3e-49 167.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG40667.1 - 2.9e-25 87.8 0.4 6e-12 45.2 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CEG40667.1 - 7.4e-17 61.5 0.0 8.5e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEG40667.1 - 1.4e-12 48.4 5.0 0.001 19.5 0.0 5.4 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 CEG40667.1 - 1.5e-11 44.4 0.1 0.00046 20.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEG40667.1 - 1e-10 42.0 0.2 0.00029 21.0 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 CEG40667.1 - 3.9e-10 40.1 5.3 0.034 14.4 0.0 5.2 3 2 2 5 5 5 3 AAA domain AAA_2 PF07724.14 CEG40667.1 - 4.9e-10 39.8 0.0 0.00012 22.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CEG40667.1 - 9.8e-09 34.9 0.0 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 CEG40667.1 - 6.6e-08 32.5 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 CEG40667.1 - 8e-08 32.6 0.0 0.019 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CEG40667.1 - 2.5e-07 30.8 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEG40667.1 - 2.9e-07 30.1 0.6 0.023 14.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CEG40667.1 - 3e-07 31.0 0.4 0.018 15.6 0.0 3.3 3 1 1 4 4 2 2 ABC transporter AAA_18 PF13238.6 CEG40667.1 - 3.4e-07 30.9 0.0 0.053 14.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 CEG40667.1 - 2.6e-06 27.1 2.2 0.69 9.5 0.1 4.3 3 1 0 4 4 4 2 AAA domain Nucleolin_bd PF16725.5 CEG40667.1 - 3.6e-06 26.5 0.1 1.1e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Nucleolin binding domain NACHT PF05729.12 CEG40667.1 - 4e-06 26.8 1.2 0.14 12.1 0.1 3.3 4 0 0 4 4 2 2 NACHT domain AAA_28 PF13521.6 CEG40667.1 - 5.6e-06 26.7 0.0 0.15 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEG40667.1 - 1.7e-05 24.6 0.0 0.21 11.3 0.0 3.1 4 0 0 4 4 2 2 Sigma-54 interaction domain TsaE PF02367.17 CEG40667.1 - 2.9e-05 24.1 0.0 0.062 13.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CEG40667.1 - 3.9e-05 23.8 0.2 0.39 10.8 0.0 4.0 3 1 1 4 4 4 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CEG40667.1 - 4.1e-05 23.0 0.3 0.11 11.7 0.0 3.0 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 CEG40667.1 - 5.6e-05 23.0 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CEG40667.1 - 5.8e-05 22.3 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CEG40667.1 - 0.00021 20.6 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 CEG40667.1 - 0.00024 21.5 0.0 0.39 11.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CEG40667.1 - 0.00024 20.9 0.0 0.29 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEG40667.1 - 0.00063 19.0 0.1 0.39 9.9 0.0 2.9 2 0 0 2 2 2 1 NB-ARC domain Vps4_C PF09336.10 CEG40667.1 - 0.00066 19.6 0.3 0.11 12.5 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 CEG40667.1 - 0.00068 19.2 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 CEG40667.1 - 0.00073 19.5 0.0 0.12 12.3 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain ATPase PF06745.13 CEG40667.1 - 0.0011 18.4 0.1 0.72 9.2 0.0 2.9 2 1 0 3 3 3 1 KaiC Cytidylate_kin2 PF13189.6 CEG40667.1 - 0.0019 18.4 0.3 7.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Cytidylate kinase-like family Viral_helicase1 PF01443.18 CEG40667.1 - 0.0027 17.5 0.0 0.7 9.6 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase CPT PF07931.12 CEG40667.1 - 0.0061 16.4 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 CEG40667.1 - 0.0063 15.8 0.0 1.6 7.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEG40667.1 - 0.0074 15.8 0.8 2.6 7.4 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 CEG40667.1 - 0.017 14.5 0.1 11 5.3 0.0 3.9 3 1 1 4 4 4 0 Bacterial TniB protein ATPase_2 PF01637.18 CEG40667.1 - 0.02 14.8 0.0 0.42 10.5 0.0 2.8 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CEG40667.1 - 0.029 14.1 0.4 3.6 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CEG40667.1 - 0.03 13.5 0.0 4.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CEG40667.1 - 0.049 13.4 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CEG40667.1 - 0.064 13.2 0.3 18 5.2 0.0 3.2 2 1 0 3 3 3 0 NTPase AAA_19 PF13245.6 CEG40667.1 - 0.073 13.4 1.8 16 5.8 0.1 3.1 2 1 1 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CEG40667.1 - 0.081 12.6 5.3 1.3 8.7 0.1 3.5 4 0 0 4 4 3 0 Cytidylate kinase AAA_11 PF13086.6 CEG40667.1 - 0.091 12.5 7.5 1.4 8.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain Bac_DnaA PF00308.18 CEG40667.1 - 0.1 12.4 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein Hydin_ADK PF17213.3 CEG40667.1 - 1.1 9.5 7.6 2.2 8.5 0.0 3.4 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain Abhydrolase_2 PF02230.16 CEG40668.1 - 1.7e-60 204.5 0.0 1.9e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CEG40668.1 - 1.6e-07 31.3 0.0 9.9e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CEG40668.1 - 1.3e-06 27.9 0.4 0.00013 21.4 0.0 2.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CEG40668.1 - 2.4e-05 23.9 0.1 7.7e-05 22.3 0.0 1.8 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 CEG40668.1 - 2.6e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CEG40668.1 - 0.00016 22.4 0.3 0.00041 21.0 0.5 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 CEG40668.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase BAAT_C PF08840.11 CEG40668.1 - 0.046 13.6 0.8 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 CEG40668.1 - 0.063 13.1 0.2 3.6 7.4 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CEG40668.1 - 0.65 9.6 2.2 50 3.4 0.2 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold FliMN_C PF01052.20 CEG40669.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term FYVE PF01363.21 CEG40671.1 - 1.7e-23 82.6 37.4 3.4e-15 55.9 8.9 3.4 4 0 0 4 4 4 2 FYVE zinc finger DnaJ PF00226.31 CEG40671.1 - 1.7e-09 37.6 1.2 3.9e-09 36.5 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain zinc_ribbon_2 PF13240.6 CEG40671.1 - 2e-05 24.1 1.3 2e-05 24.1 1.3 2.7 2 0 0 2 2 2 1 zinc-ribbon domain FYVE_2 PF02318.16 CEG40671.1 - 0.0019 18.4 4.4 0.0019 18.4 4.4 8.4 9 1 0 10 10 10 3 FYVE-type zinc finger DZR PF12773.7 CEG40671.1 - 0.0048 16.9 0.5 0.0048 16.9 0.5 5.6 4 2 0 4 4 4 1 Double zinc ribbon PX PF00787.24 CEG40671.1 - 0.0098 15.9 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 PX domain CTP_transf_1 PF01148.20 CEG40676.1 - 8.8e-36 124.0 24.3 3.2e-35 122.2 17.8 2.6 2 1 0 2 2 2 2 Cytidylyltransferase family DUF5090 PF17009.5 CEG40677.1 - 0.16 11.9 2.4 0.17 11.8 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Nnf1 PF03980.14 CEG40678.1 - 1.6e-15 57.4 15.8 3.1e-15 56.5 15.8 1.5 1 0 0 1 1 1 1 Nnf1 bZIP_1 PF00170.21 CEG40678.1 - 0.014 15.5 7.2 0.014 15.5 7.2 2.2 2 1 0 2 2 2 0 bZIP transcription factor PvlArgDC PF01862.16 CEG40678.1 - 0.8 9.5 5.3 5.3 6.8 5.2 2.0 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Stathmin PF00836.19 CEG40678.1 - 4.7 7.2 22.2 2 8.4 19.4 1.8 1 1 1 2 2 2 0 Stathmin family Atg14 PF10186.9 CEG40678.1 - 5.7 5.9 13.0 8.1 5.4 13.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ApoO PF09769.9 CEG40679.1 - 0.71 9.8 2.6 27 4.8 0.1 2.8 2 1 0 2 2 2 0 Apolipoprotein O DUF4378 PF14309.6 CEG40679.1 - 0.82 10.0 6.0 8.2 6.8 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) Arv1 PF04161.13 CEG40680.1 - 2.3e-47 161.9 6.3 2.9e-47 161.6 6.3 1.1 1 0 0 1 1 1 1 Arv1-like family TF_Zn_Ribbon PF08271.12 CEG40680.1 - 0.0017 17.8 1.6 0.0029 17.1 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.7 CEG40680.1 - 0.16 12.0 0.2 0.29 11.2 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF872 PF05915.12 CEG40681.1 - 1.3e-14 54.3 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) YrhK PF14145.6 CEG40681.1 - 0.014 15.2 1.9 0.03 14.2 1.5 1.7 1 1 0 1 1 1 0 YrhK-like protein VIT1 PF01988.19 CEG40681.1 - 0.037 13.9 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 VIT family Phage_holin_3_6 PF07332.11 CEG40681.1 - 0.1 12.6 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 CEG40681.1 - 0.38 10.4 2.5 0.52 9.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mg_trans_NIPA PF05653.14 CEG40682.1 - 3e-08 33.1 13.9 4.8e-07 29.2 13.9 2.1 1 1 0 1 1 1 1 Magnesium transporter NIPA Frizzled PF01534.17 CEG40682.1 - 0.07 12.2 1.9 2.4 7.1 0.2 2.9 3 0 0 3 3 3 0 Frizzled/Smoothened family membrane region EamA PF00892.20 CEG40682.1 - 2.5 8.3 30.6 0.034 14.3 2.8 4.3 4 1 0 4 4 4 0 EamA-like transporter family zf-CCHC_6 PF15288.6 CEG40683.1 - 0.0017 18.2 2.4 0.0037 17.1 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEG40683.1 - 0.013 15.2 1.6 0.03 14.1 1.6 1.7 1 1 0 1 1 1 0 C2H2 zinc-finger Fanconi_A PF03511.14 CEG40683.1 - 0.025 14.5 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein zf-CCHC_4 PF14392.6 CEG40683.1 - 0.037 13.8 0.8 0.071 12.9 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CEG40683.1 - 0.061 13.4 2.2 0.061 13.4 2.2 1.8 2 0 0 2 2 2 0 Zinc knuckle AT_hook PF02178.19 CEG40683.1 - 0.078 12.9 3.9 0.078 12.9 3.9 2.5 2 0 0 2 2 2 0 AT hook motif zf-RING_5 PF14634.6 CEG40684.1 - 1.4e-08 34.5 9.8 1.4e-08 34.5 9.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG40684.1 - 2.3e-05 24.6 9.8 5e-05 23.6 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEG40684.1 - 0.00018 21.3 7.3 0.00057 19.7 7.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG40684.1 - 0.00045 20.0 10.5 0.0034 17.2 10.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG40684.1 - 0.00092 19.0 8.1 0.0021 17.9 8.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG40684.1 - 0.0031 17.5 7.6 0.0085 16.1 7.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG40684.1 - 0.019 14.8 5.9 0.019 14.8 5.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 CEG40684.1 - 0.022 14.9 5.3 0.044 13.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HIGH_NTase1 PF05636.11 CEG40684.1 - 0.024 13.9 0.9 0.38 9.9 1.9 2.0 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase zf-RING_6 PF14835.6 CEG40684.1 - 0.085 12.7 4.0 0.16 11.8 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4407 PF14362.6 CEG40684.1 - 0.4 10.0 2.4 0.53 9.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_5 PF17121.5 CEG40684.1 - 0.47 10.4 3.8 1.2 9.0 3.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CREPT PF16566.5 CEG40684.1 - 0.63 10.2 7.1 1 9.5 6.0 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fer2_3 PF13085.6 CEG40684.1 - 0.97 9.5 4.4 0.25 11.4 0.9 1.8 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain HypA PF01155.19 CEG40684.1 - 1.1 9.3 5.4 33 4.5 5.4 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0449 PF15136.6 CEG40684.1 - 1.2 9.6 4.9 2.5 8.6 4.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 zf-RING_4 PF14570.6 CEG40684.1 - 1.7 8.5 8.1 4.9 7.0 8.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CEG40684.1 - 2.9 8.1 7.2 8.1 6.7 7.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C4H2 PF10146.9 CEG40685.1 - 1.2e-05 25.7 9.2 1.2e-05 25.7 9.2 4.0 3 1 2 5 5 5 1 Zinc finger-containing protein CATSPERD PF15020.6 CEG40685.1 - 0.032 12.5 0.0 0.047 12.0 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta CxxCxxCC PF03692.15 CEG40685.1 - 1 10.1 5.4 0.7 10.6 0.8 3.1 3 0 0 3 3 3 0 Putative zinc- or iron-chelating domain HALZ PF02183.18 CEG40685.1 - 1.4 9.2 8.6 0.57 10.4 0.1 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper RCC1 PF00415.18 CEG40687.1 - 0.038 14.6 1.5 0.095 13.3 1.5 1.7 1 1 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat YtxH PF12732.7 CEG40688.1 - 0.94 10.1 9.6 1.3 9.6 9.6 1.3 1 0 0 1 1 1 0 YtxH-like protein Ank_2 PF12796.7 CEG40693.1 - 1.9e-10 41.2 2.1 3.7e-06 27.4 2.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG40693.1 - 3.9e-08 33.4 7.9 9.5e-08 32.2 5.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG40693.1 - 4.9e-07 30.2 2.8 0.00019 21.9 0.4 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG40693.1 - 1.8e-05 24.8 1.1 0.054 14.1 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEG40693.1 - 0.00027 21.2 7.5 0.039 14.4 0.7 3.0 3 1 0 3 3 3 2 Ankyrin repeat LytR_cpsA_psr PF03816.14 CEG40693.1 - 0.063 13.4 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain Fer2 PF00111.27 CEG40699.1 - 4.5e-11 42.5 1.0 6.8e-11 42.0 1.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 CEG40699.1 - 0.018 14.6 0.2 0.038 13.6 0.2 1.6 1 0 0 1 1 1 0 Magnetochrome domain VPS9 PF02204.18 CEG40700.1 - 2.5e-10 40.5 0.1 8.6e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ras PF00071.22 CEG40701.1 - 6.2e-41 139.7 0.0 9.4e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Ras family KHA PF11834.8 CEG40701.1 - 5e-16 58.5 0.0 5.5e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel Roc PF08477.13 CEG40701.1 - 7.8e-14 51.9 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEG40701.1 - 6.2e-05 22.6 0.0 0.0002 21.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CEG40701.1 - 8.8e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEG40701.1 - 0.16 11.9 0.2 21 5.0 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 CEG40701.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Cys_Met_Meta_PP PF01053.20 CEG40702.1 - 1.7e-21 76.3 0.4 8.1e-11 41.1 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme AOX PF01786.17 CEG40703.1 - 3.8e-92 307.7 0.0 4.5e-92 307.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 CEG40703.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Methyltransf_11 PF08241.12 CEG40704.1 - 3.6e-08 33.9 0.0 7.1e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG40704.1 - 1.3e-05 25.9 0.0 6.5e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG40704.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG40704.1 - 0.0038 16.6 0.0 0.0095 15.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEG40704.1 - 0.01 16.6 0.0 0.026 15.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEG40704.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Transthyretin PF00576.21 CEG40705.1 - 1.1e-37 129.1 1.1 1.3e-37 128.9 1.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family PEPCK_GTP PF00821.18 CEG40706.1 - 0.14 11.0 0.0 0.69 8.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain FYVE PF01363.21 CEG40707.1 - 8.6e-16 57.8 7.1 1.2e-15 57.4 7.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.6 CEG40707.1 - 0.014 15.7 5.0 0.014 15.7 5.0 1.6 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.16 CEG40707.1 - 0.019 15.2 2.7 0.024 14.8 2.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 CEG40707.1 - 0.033 14.2 7.0 0.056 13.4 7.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1247 PF06851.11 CEG40707.1 - 0.099 12.6 0.3 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) zf-B_box PF00643.24 CEG40707.1 - 0.11 12.6 5.6 0.46 10.7 5.6 1.9 1 1 0 1 1 1 0 B-box zinc finger zf-RING_UBOX PF13445.6 CEG40707.1 - 0.22 11.6 7.4 0.061 13.4 4.4 1.7 2 0 0 2 2 2 0 RING-type zinc-finger SAP PF02037.27 CEG40709.1 - 8.5e-11 41.4 0.3 8.5e-11 41.4 0.3 2.3 2 0 0 2 2 2 1 SAP domain INCENP_ARK-bind PF03941.15 CEG40709.1 - 7.3e-09 35.4 6.1 1.5e-08 34.4 0.1 3.8 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region CHAT PF12770.7 CEG40711.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain FHA PF00498.26 CEG40711.1 - 1.3e-07 31.8 0.2 3.2e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 FHA domain NACHT PF05729.12 CEG40711.1 - 5.8e-05 23.1 0.0 0.00024 21.0 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 CEG40711.1 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG40711.1 - 0.0041 17.5 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CEG40711.1 - 0.011 16.3 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG40711.1 - 0.11 12.8 0.3 0.34 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain MAT1 PF06391.13 CEG40712.1 - 2.8e-06 27.3 2.9 3.4e-06 27.0 2.9 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF4279 PF14106.6 CEG40712.1 - 0.1 12.8 0.3 0.26 11.5 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) DSHCT PF08148.12 CEG40713.1 - 4.2e-54 182.6 0.7 4.2e-54 182.6 0.7 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CEG40713.1 - 3.3e-23 83.0 1.8 8.9e-23 81.6 1.8 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 CEG40713.1 - 1.3e-14 54.4 0.0 3.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG40713.1 - 2.7e-06 27.7 0.2 1.1e-05 25.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Ski2_N PF17911.1 CEG40713.1 - 0.0032 17.3 0.1 0.008 16.0 0.1 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region AAA_22 PF13401.6 CEG40713.1 - 0.02 15.2 0.0 0.26 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Staygreen PF12638.7 CEG40714.1 - 0.016 15.0 0.3 0.043 13.6 0.2 1.8 1 1 0 1 1 1 0 Staygreen protein DAPDH_C PF16654.5 CEG40714.1 - 0.66 9.8 5.2 0.15 11.9 0.5 2.2 2 1 1 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain SlyX PF04102.12 CEG40714.1 - 4.1 8.1 7.8 2 9.1 0.2 4.0 4 1 0 4 4 4 0 SlyX UNC-50 PF05216.13 CEG40716.1 - 1e-69 234.5 20.3 1.4e-69 234.0 20.3 1.1 1 0 0 1 1 1 1 UNC-50 family Sec1 PF00995.23 CEG40718.1 - 1.9e-62 212.3 0.0 2.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family EIIA-man PF03610.16 CEG40718.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component PDZ_1 PF12812.7 CEG40718.1 - 0.12 12.5 0.7 8.8 6.4 0.1 3.3 4 0 0 4 4 4 0 PDZ-like domain p450 PF00067.22 CEG40719.1 - 2.7e-69 234.1 0.1 3.1e-69 233.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 CEG40721.1 - 2.1e-13 51.2 0.0 3.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Retrotran_gag_3 PF14244.6 CEG40722.1 - 1.1e-08 34.7 0.1 2.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG40722.1 - 0.0002 20.9 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 CEG40722.1 - 0.019 14.7 0.2 0.029 14.0 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4376 PF14301.6 CEG40722.1 - 0.087 13.2 0.3 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) Antimicrobial13 PF08108.11 CEG40726.1 - 3.2 8.0 4.5 10 6.4 0.7 2.7 2 0 0 2 2 2 0 Halocidin family Kinesin PF00225.23 CEG40728.1 - 3.8e-109 364.6 2.0 3.8e-109 364.6 2.0 3.6 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG40728.1 - 4.4e-26 91.6 0.1 4.4e-26 91.6 0.1 3.3 2 1 0 2 2 2 1 Microtubule binding HMMR_C PF15908.5 CEG40728.1 - 0.00072 19.9 19.9 0.00072 19.9 19.9 9.3 2 2 5 9 9 9 3 Hyaluronan mediated motility receptor C-terminal Atg14 PF10186.9 CEG40728.1 - 0.0011 18.1 24.2 0.0011 18.1 24.2 9.4 1 1 6 9 9 9 2 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 CEG40728.1 - 0.0085 16.6 18.5 0.0085 16.6 18.5 10.9 2 1 7 10 10 10 1 Fez1 DUF3800 PF12686.7 CEG40728.1 - 0.67 10.6 11.8 3e+03 -1.2 0.0 6.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Ank_4 PF13637.6 CEG40729.1 - 1.9e-16 60.2 0.3 5.1e-10 39.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG40729.1 - 1.8e-14 54.1 0.3 2.3e-13 50.5 0.0 2.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG40729.1 - 3.4e-13 49.5 0.9 4e-09 36.6 0.4 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG40729.1 - 4e-11 42.1 0.4 4.1e-05 23.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CEG40729.1 - 4.3e-10 39.6 0.0 3.7e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat LPD39 PF18858.1 CEG40729.1 - 0.16 12.0 6.6 0.14 12.2 3.3 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 CBFD_NFYB_HMF PF00808.23 CEG40730.1 - 3.3e-26 91.4 0.1 4.3e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEG40730.1 - 0.0008 19.8 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CEG40730.1 - 0.003 17.6 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CEG40730.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CEG40730.1 - 0.014 15.9 0.5 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 CEG40730.1 - 0.055 13.5 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CtaG_Cox11 PF04442.14 CEG40731.1 - 4.2e-60 202.2 0.2 6.3e-60 201.6 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 GCV_H PF01597.19 CEG40731.1 - 4.9e-40 136.2 0.1 7.8e-40 135.6 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CEG40731.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain UCR_Fe-S_N PF10399.9 CEG40731.1 - 0.0015 17.8 0.1 0.0034 16.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Biotin_lipoyl PF00364.22 CEG40731.1 - 0.0021 17.8 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF5337 PF17272.2 CEG40731.1 - 0.12 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) PseudoU_synth_1 PF01416.20 CEG40732.1 - 5.7e-13 49.3 0.3 6e-11 42.8 0.0 3.1 3 1 0 3 3 3 2 tRNA pseudouridine synthase RVT_2 PF07727.14 CEG40734.1 - 5.1e-16 59.0 0.0 8.1e-16 58.4 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PrmC_N PF17827.1 CEG40736.1 - 5.7e-12 46.0 0.1 2e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 CEG40736.1 - 9.3e-12 45.0 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG40736.1 - 1.5e-09 37.6 0.0 3.8e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG40736.1 - 2.1e-08 34.7 0.0 5.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG40736.1 - 5.7e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CEG40736.1 - 3.7e-05 24.4 0.0 8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG40736.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG40736.1 - 0.00056 20.5 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CEG40736.1 - 0.003 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.12 CEG40736.1 - 0.0052 16.2 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_2 PF00891.18 CEG40736.1 - 0.0055 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Cons_hypoth95 PF03602.15 CEG40736.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 CEG40736.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_18 PF12847.7 CEG40736.1 - 0.028 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.11 CEG40736.1 - 0.077 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase CMAS PF02353.20 CEG40736.1 - 0.24 10.6 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HALZ PF02183.18 CEG40737.1 - 0.035 14.3 25.5 0.077 13.2 2.4 4.7 4 1 1 5 5 5 0 Homeobox associated leucine zipper Macoilin PF09726.9 CEG40737.1 - 0.73 8.3 44.2 0.98 7.9 44.2 1.2 1 0 0 1 1 1 0 Macoilin family JIP_LZII PF16471.5 CEG40737.1 - 2 8.7 25.5 0.25 11.6 1.5 4.6 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II FlaC_arch PF05377.11 CEG40737.1 - 7.1 7.1 19.5 1.1 9.7 0.8 4.7 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) Ank_2 PF12796.7 CEG40738.1 - 5.4e-17 62.2 7.7 1e-06 29.2 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG40738.1 - 1.1e-13 50.0 3.4 0.0061 17.0 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEG40738.1 - 8.4e-12 45.1 2.2 3e-06 27.4 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG40738.1 - 6.9e-11 42.1 1.9 0.029 14.8 0.2 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CEG40738.1 - 4.7e-10 39.8 0.2 0.002 18.7 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF5089 PF17002.5 CEG40739.1 - 0.0007 19.5 4.4 0.004 17.0 1.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) Syntaxin-6_N PF09177.11 CEG40739.1 - 0.025 15.1 4.9 0.028 15.0 0.3 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal APG17 PF04108.12 CEG40739.1 - 0.077 12.1 4.2 0.33 10.0 4.2 2.1 1 1 0 1 1 1 0 Autophagy protein Apg17 AKNA PF12443.8 CEG40739.1 - 0.079 13.6 0.6 0.079 13.6 0.6 1.9 2 0 0 2 2 1 0 AT-hook-containing transcription factor Laminin_II PF06009.12 CEG40739.1 - 0.081 12.9 1.0 12 6.0 0.9 2.8 2 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 CEG40739.1 - 0.081 13.2 3.3 0.97 9.7 0.4 3.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 CEG40739.1 - 0.098 12.5 5.1 0.037 13.9 1.5 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Apolipoprotein PF01442.18 CEG40739.1 - 0.18 11.7 4.4 0.5 10.2 1.1 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 CEG40739.1 - 0.31 11.5 2.9 2.4 8.7 1.3 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 CEG40739.1 - 0.78 9.9 6.4 0.7 10.0 1.0 2.3 2 0 0 2 2 2 0 Tropomyosin like CREPT PF16566.5 CEG40739.1 - 1.1 9.4 7.9 0.25 11.5 1.6 2.5 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 CEG40739.1 - 1.1 9.3 9.7 1.8 8.6 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 CEG40739.1 - 1.2 9.7 7.7 0.58 10.8 0.4 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.8 CEG40739.1 - 1.3 8.3 7.5 0.5 9.6 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 CEG40739.1 - 2.3 8.8 8.1 0.34 11.4 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 zf-U1 PF06220.12 CEG40740.1 - 1.9e-19 69.1 6.3 2.4e-19 68.8 6.3 1.1 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 CEG40740.1 - 0.046 13.6 1.5 0.062 13.2 1.5 1.2 1 0 0 1 1 1 0 CLIP1 zinc knuckle zf-CCHC PF00098.23 CEG40742.1 - 0.013 15.6 2.4 0.019 15.1 2.4 1.2 1 0 0 1 1 1 0 Zinc knuckle COPI_assoc PF08507.10 CEG40744.1 - 3.2e-10 40.2 5.5 4.1e-10 39.8 5.5 1.1 1 0 0 1 1 1 1 COPI associated protein MAT1 PF06391.13 CEG40745.1 - 0.0023 17.8 2.7 0.0042 17.0 2.7 1.4 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 CAP_GLY PF01302.25 CEG40747.1 - 4.6e-23 81.0 0.6 7.7e-23 80.3 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain Filament PF00038.21 CEG40747.1 - 0.00017 21.3 31.0 0.00017 21.3 31.0 5.1 3 1 1 4 4 4 3 Intermediate filament protein Pox_A8 PF04745.12 CEG40747.1 - 0.059 12.4 0.6 0.13 11.3 0.6 1.5 1 0 0 1 1 1 0 VITF-3 subunit protein DUF5578 PF17741.1 CEG40748.1 - 9.8e-10 38.3 14.0 3.2e-07 30.0 14.0 3.0 1 1 0 1 1 1 1 Family of unknown function (DUF5578) Med11 PF10280.9 CEG40749.1 - 9.8e-12 45.5 0.1 1.4e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Mating_N PF12731.7 CEG40749.1 - 0.015 15.4 1.5 0.54 10.4 0.7 2.4 2 1 0 2 2 2 0 Mating-type protein beta 1 HAUS4 PF14735.6 CEG40749.1 - 0.064 12.9 0.1 4.2 7.0 0.0 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 4 TisB_toxin PF13939.6 CEG40749.1 - 0.12 12.2 0.8 0.28 11.0 0.8 1.7 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Prominin PF05478.11 CEG40750.1 - 0.00035 18.7 0.6 0.00035 18.7 0.6 3.1 3 0 0 3 3 3 2 Prominin GNVR PF13807.6 CEG40750.1 - 0.026 14.4 0.9 0.57 10.1 0.2 2.8 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF948 PF06103.11 CEG40750.1 - 0.089 13.1 5.1 10 6.5 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1218 PF06749.12 CEG40750.1 - 0.61 10.6 13.5 0.3 11.6 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) YiaAB PF05360.14 CEG40750.1 - 7 7.0 9.9 5.4 7.3 0.5 3.8 3 0 0 3 3 3 0 yiaA/B two helix domain Amino_oxidase PF01593.24 CEG40751.1 - 1.5e-41 143.1 0.0 1.9e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEG40751.1 - 2.6e-12 46.8 0.0 5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG40751.1 - 7.1e-06 25.8 0.0 3.1e-05 23.7 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase MCRA PF06100.11 CEG40751.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 CEG40751.1 - 0.03 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 CEG40751.1 - 0.084 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CEG40751.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEG40751.1 - 0.24 10.2 0.2 0.34 9.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CFAP91 PF14738.6 CEG40752.1 - 3.1e-49 167.0 8.8 3.1e-49 167.0 8.8 3.4 3 1 1 4 4 4 1 Cilia- and flagella-associated protein 91 Ax_dynein_light PF10211.9 CEG40753.1 - 1.1e-70 237.4 0.8 1.2e-70 237.2 0.8 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain HOOK PF05622.12 CEG40753.1 - 8.1e-05 21.0 6.0 0.0001 20.7 6.0 1.1 1 0 0 1 1 1 1 HOOK protein DivIC PF04977.15 CEG40753.1 - 0.17 11.7 7.3 0.052 13.3 3.2 2.2 2 1 0 2 2 2 0 Septum formation initiator Taxilin PF09728.9 CEG40755.1 - 8.1e-72 242.0 59.9 8.1e-72 242.0 59.9 1.7 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.6 CEG40755.1 - 0.0041 16.9 9.8 0.0041 16.9 9.8 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4201) bZIP_2 PF07716.15 CEG40755.1 - 0.085 13.0 0.6 0.085 13.0 0.6 6.5 6 3 0 6 6 6 0 Basic region leucine zipper DUF3800 PF12686.7 CEG40755.1 - 1.4 9.6 4.7 56 4.4 4.7 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Virulence_fact PF13769.6 CEG40755.1 - 3 8.2 11.0 0.21 11.9 0.8 3.7 3 1 1 4 4 4 0 Virulence factor MIS13 PF08202.11 CEG40755.1 - 4.9 6.4 37.8 0.48 9.7 8.9 3.2 1 1 0 2 2 2 0 Mis12-Mtw1 protein family Ras PF00071.22 CEG40756.1 - 1e-16 60.9 0.0 1.4e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG40756.1 - 1.3e-11 44.7 0.0 3.3e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG40756.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG40756.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zip PF02535.22 CEG40757.1 - 9.2e-37 127.0 8.0 1.2e-36 126.7 8.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter zf-rbx1 PF12678.7 CEG40758.1 - 1.4e-25 89.3 12.9 2.2e-25 88.7 12.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEG40758.1 - 4e-18 65.2 9.9 5.2e-18 64.9 9.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CEG40758.1 - 2e-06 28.0 15.1 8.1e-05 22.9 15.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG40758.1 - 7.2e-05 22.5 3.5 7.2e-05 22.5 3.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG40758.1 - 0.00093 19.0 11.8 0.016 15.1 11.8 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG40758.1 - 0.096 12.6 10.9 0.31 10.9 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG40758.1 - 0.18 11.6 15.7 18 5.2 15.7 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 CEG40758.1 - 0.18 12.0 8.9 1.9 8.7 9.4 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CEG40758.1 - 0.29 10.8 15.4 46 3.7 15.4 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CEG40758.1 - 0.38 10.8 8.0 1.5 8.9 8.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CEG40758.1 - 8.7 6.4 12.9 66 3.6 12.9 2.5 1 1 0 1 1 1 0 zinc-RING finger domain RVT_2 PF07727.14 CEG40760.1 - 1.7e-35 122.9 0.4 1.3e-19 70.8 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.27 CEG40762.1 - 1.2e-52 175.8 9.4 7.5e-19 67.5 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SAT PF16073.5 CEG40762.1 - 0.33 10.7 3.5 4.8 6.8 0.3 2.8 2 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis E1-E2_ATPase PF00122.20 CEG40764.1 - 1.6e-47 161.4 1.7 1.6e-47 161.4 1.7 3.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CEG40764.1 - 1.5e-15 58.1 0.1 5.8e-15 56.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG40764.1 - 1.7e-13 50.1 0.0 4.8e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEG40764.1 - 0.0029 17.7 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEG40764.1 - 0.0057 16.4 0.9 0.008 15.9 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pox_P21 PF05313.12 CEG40764.1 - 3.8 7.1 8.8 0.43 10.1 4.0 1.8 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Sulfate_transp PF00916.20 CEG40765.1 - 1.7e-40 139.0 12.1 2.4e-40 138.5 12.1 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CEG40765.1 - 9.2e-13 48.1 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CEG40765.1 - 1.6e-07 31.0 0.0 4.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 STAS domain DUF4149 PF13664.6 CEG40765.1 - 3.7 7.9 8.7 1.3 9.4 0.6 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Cse1 PF08506.10 CEG40766.1 - 7.9e-08 31.5 0.2 1.9e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CEG40766.1 - 8e-08 32.1 2.3 4.4e-07 29.7 0.2 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CEG40766.1 - 7.8e-06 26.0 4.0 0.00061 19.9 0.1 3.9 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep_4 PF18808.1 CEG40766.1 - 0.00056 20.1 0.6 0.012 15.9 0.1 2.8 2 0 0 2 2 2 1 Importin repeat RICTOR_V PF14668.6 CEG40767.1 - 0.021 15.1 0.0 3.7 7.9 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 SnoaL_4 PF13577.6 CEG40768.1 - 1.9e-11 44.2 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 CEG40768.1 - 0.013 16.1 0.0 0.026 15.1 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 CEG40768.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) RecO_N PF11967.8 CEG40768.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal Hexapep PF00132.24 CEG40770.1 - 2.5e-11 42.8 11.5 4.2e-06 26.3 1.1 5.0 2 2 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEG40770.1 - 0.00026 20.7 8.6 0.00055 19.6 1.9 3.7 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CEG40770.1 - 0.0093 14.9 2.4 0.069 12.1 2.2 2.0 1 1 0 1 1 1 1 L-fucokinase SHIPPO-rpt PF07004.12 CEG40771.1 - 2.2e-15 56.7 10.5 0.094 13.7 0.0 7.9 8 0 0 8 8 8 7 Sperm-tail PG-rich repeat Metallophos PF00149.28 CEG40772.1 - 1.1e-12 48.9 0.1 1.5e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5130 PF17174.4 CEG40772.1 - 0.13 12.5 0.0 6 7.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5130) INCENP_N PF12178.8 CEG40772.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal F1F0-ATPsyn_F PF10791.9 CEG40773.1 - 0.016 15.7 0.0 0.021 15.3 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi zf-LYAR PF08790.11 CEG40774.1 - 4.8e-15 55.1 4.7 3.1e-14 52.6 1.7 2.4 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger C1_4 PF07975.12 CEG40774.1 - 0.22 11.8 4.5 0.95 9.7 4.5 2.1 1 0 0 1 1 1 0 TFIIH C1-like domain zf-UBR PF02207.20 CEG40775.1 - 4.1e-13 49.3 8.5 4.1e-13 49.3 8.5 4.0 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Oxidored_FMN PF00724.20 CEG40776.1 - 1.7e-87 293.9 0.0 2.4e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CEG40776.1 - 5.3e-25 88.2 0.5 1.1e-24 87.2 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEG40776.1 - 7.4e-09 36.1 7.0 0.00045 20.7 0.5 4.1 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG40776.1 - 1.1e-08 35.2 0.3 1e-07 32.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEG40776.1 - 1.3e-06 27.9 0.3 0.0018 17.6 0.0 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG40776.1 - 1.6e-05 23.8 1.3 3.2e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 CEG40776.1 - 0.00041 19.6 0.3 0.00093 18.4 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 CEG40776.1 - 0.00061 19.7 1.2 0.03 14.2 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 CEG40776.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEG40776.1 - 0.0024 17.2 0.6 0.3 10.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CEG40776.1 - 0.012 15.3 8.8 0.041 13.5 0.6 3.5 3 2 0 4 4 4 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 CEG40776.1 - 0.021 14.4 0.2 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CEG40776.1 - 0.034 13.5 0.9 0.12 11.7 0.0 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CEG40776.1 - 0.034 13.5 1.1 0.58 9.5 0.1 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 CEG40776.1 - 0.045 12.8 0.5 0.091 11.8 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 CEG40776.1 - 0.061 13.0 1.7 45 3.7 0.0 3.4 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.19 CEG40776.1 - 0.073 11.5 0.1 0.88 7.9 0.0 2.4 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 CEG40776.1 - 0.093 12.0 0.1 0.83 8.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 CEG40776.1 - 0.11 12.5 0.2 13 5.8 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PH_18 PF18469.1 CEG40776.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain ThiF PF00899.21 CEG40776.1 - 0.17 11.3 0.1 0.95 8.8 0.1 2.0 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 CEG40776.1 - 0.57 10.2 5.0 3 7.8 0.1 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding IQ PF00612.27 CEG40778.1 - 1.7e-15 55.3 95.3 0.004 16.8 2.8 14.4 15 0 0 15 15 15 9 IQ calmodulin-binding motif LRR_4 PF12799.7 CEG40778.1 - 1.9e-08 34.5 17.1 0.97 9.9 0.1 8.0 8 2 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG40778.1 - 3.3e-08 32.9 21.6 0.073 13.2 0.1 9.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.6 CEG40778.1 - 0.00021 21.0 0.1 0.87 9.4 0.0 4.4 4 1 1 5 5 5 2 Leucine rich repeat zf-C3HC4 PF00097.25 CEG40778.1 - 0.04 13.8 0.9 0.16 11.9 0.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LRR_1 PF00560.33 CEG40778.1 - 0.9 10.3 16.9 96 4.2 1.6 8.3 8 2 0 8 8 8 0 Leucine Rich Repeat Glucokinase PF02685.16 CEG40779.1 - 4.8e-81 272.2 0.0 6.2e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Glucokinase VDE PF07137.11 CEG40779.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 VDE lipocalin domain DLIC PF05783.11 CEG40781.1 - 0.032 13.1 0.8 0.17 10.7 0.1 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Trypsin_2 PF13365.6 CEG40782.1 - 1.6e-14 55.0 0.0 3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG40782.1 - 2.6e-05 24.2 0.2 0.0001 22.2 0.2 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 CEG40782.1 - 0.0035 16.1 0.0 0.0035 16.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase S46 TMF_TATA_bd PF12325.8 CEG40783.1 - 0.0012 19.0 3.5 0.017 15.4 0.3 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 CEG40783.1 - 0.0026 17.5 0.2 0.0048 16.6 0.2 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 CEG40783.1 - 0.025 14.7 1.5 0.044 13.9 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Luteo_PO PF04662.13 CEG40783.1 - 0.031 14.0 0.3 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 Luteovirus P0 protein DivIC PF04977.15 CEG40783.1 - 0.089 12.6 0.7 0.22 11.3 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF5082 PF16888.5 CEG40783.1 - 0.12 12.7 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SlyX PF04102.12 CEG40783.1 - 0.96 10.1 3.7 4.3 8.0 3.4 2.2 1 1 1 2 2 2 0 SlyX Pkinase PF00069.25 CEG40784.1 - 8.5e-11 41.7 0.0 9.5e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CEG40785.1 - 5.1e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 CEG40785.1 - 2.4e-09 37.6 0.0 7.8e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 CEG40785.1 - 2.2e-07 30.5 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 CEG40785.1 - 7.3e-07 28.6 0.7 0.6 10.2 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CEG40785.1 - 9.2e-07 29.2 0.7 0.047 14.2 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG40785.1 - 0.00011 21.5 0.8 0.16 11.6 0.1 3.2 3 0 0 3 3 3 2 EF hand PH_8 PF15409.6 CEG40785.1 - 0.0022 18.3 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Fib_alpha PF08702.10 CEG40786.1 - 0.024 14.8 4.8 0.32 11.2 0.3 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 CEG40786.1 - 2.8 7.2 6.5 0.58 9.5 1.0 2.0 1 1 0 2 2 2 0 FAM76 protein MMS1_N PF10433.9 CEG40787.1 - 1.1e-134 449.7 0.0 2.5e-134 448.6 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEG40787.1 - 1.3e-90 304.0 0.0 3.4e-89 299.4 0.0 2.5 2 1 1 3 3 3 1 CPSF A subunit region PIG-H PF10181.9 CEG40788.1 - 2.1e-13 49.9 0.4 3.6e-13 49.2 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF3093 PF11292.8 CEG40788.1 - 4.3 7.6 9.0 1.5 9.0 6.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3093) Glyco_hydro_30 PF02055.16 CEG40789.1 - 1.6e-89 300.3 0.4 2.5e-89 299.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 CEG40789.1 - 1e-11 45.2 12.9 6.3e-09 36.2 4.1 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 CEG40789.1 - 1.7e-10 40.9 0.3 5.3e-10 39.4 0.3 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 CEG40789.1 - 5.3e-06 25.9 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 RicinB_lectin_2 PF14200.6 CEG40789.1 - 4e-05 24.3 0.7 0.00013 22.6 0.7 1.9 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 CEG40789.1 - 0.0001 22.1 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 CEG40790.1 - 1.8e-89 300.1 1.0 2.3e-89 299.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 CEG40790.1 - 2.7e-10 40.6 2.1 8.1e-08 32.6 0.5 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_59 PF02057.15 CEG40790.1 - 1.6e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 CEG40790.1 - 9.7e-06 25.7 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain RicinB_lectin_2 PF14200.6 CEG40790.1 - 0.0038 17.9 0.0 0.6 10.9 0.1 2.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 CEG40790.1 - 0.0086 15.7 0.5 0.061 12.9 0.5 2.0 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.12 CEG40790.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminal domain DEAD PF00270.29 CEG40794.1 - 8.5e-45 152.7 0.3 7.5e-44 149.6 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG40794.1 - 2e-17 63.5 0.1 2.7e-16 59.9 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG40794.1 - 5.7e-08 33.0 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CEG40794.1 - 0.0057 16.0 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain Nop PF01798.18 CEG40795.1 - 6.3e-67 225.4 0.0 9.9e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CEG40795.1 - 9.5e-37 126.6 4.5 2.2e-36 125.4 4.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain DUF465 PF04325.13 CEG40795.1 - 0.069 13.2 0.7 0.17 11.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) 2OG-FeII_Oxy PF03171.20 CEG40796.1 - 5e-05 23.7 0.1 0.00022 21.6 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ComS PF17584.2 CEG40797.1 - 0.64 9.6 6.0 8.7 6.0 0.4 2.7 2 0 0 2 2 2 0 Bacillus competence protein S LRR_6 PF13516.6 CEG40798.1 - 1.2e-15 56.1 8.6 6.3e-05 22.7 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CEG40798.1 - 0.042 14.4 3.6 24 6.0 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 CEG40798.1 - 5.1 6.9 9.6 19 5.1 2.0 3.5 2 1 1 3 3 3 0 Leucine rich repeat IGPS PF00218.21 CEG40799.1 - 2.6e-61 207.0 1.1 1e-60 205.1 0.2 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 CEG40799.1 - 3.4e-38 131.4 0.0 9.5e-33 113.6 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3605 PF12239.8 CEG40800.1 - 0.0013 19.1 6.2 0.0099 16.2 6.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) cNMP_binding PF00027.29 CEG40801.1 - 0.0017 18.4 0.0 0.0048 16.9 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Spc24 PF08286.11 CEG40801.1 - 0.041 14.1 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FSH1 PF03959.13 CEG40802.1 - 1.4e-30 106.5 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CEG40802.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 CEG40802.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family NTF2 PF02136.20 CEG40803.1 - 7.9e-28 97.4 0.4 8.8e-28 97.3 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Dimeth_Pyl PF09505.10 CEG40803.1 - 0.093 11.2 0.0 0.093 11.2 0.0 1.0 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DREV PF05219.12 CEG40805.1 - 2.9e-61 206.9 0.0 4.2e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase DBR1 PF05011.13 CEG40805.1 - 1.7e-26 93.3 0.0 3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Methyltransf_23 PF13489.6 CEG40805.1 - 3.4e-12 46.5 0.0 6.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG40805.1 - 2.2e-08 34.7 0.0 6.6e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG40805.1 - 4.3e-07 30.5 0.0 1.1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG40805.1 - 1.7e-06 28.6 0.0 7.1e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 CEG40805.1 - 1.8e-05 23.9 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Metallophos PF00149.28 CEG40805.1 - 0.00011 22.8 0.1 0.00019 22.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MetW PF07021.12 CEG40805.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 CEG40805.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CEG40805.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 CEG40805.1 - 0.092 12.4 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein S (NodS) MTS PF05175.14 CEG40805.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 CEG40808.1 - 1.7e-20 73.6 0.1 1.8e-09 37.3 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 CEG40808.1 - 6.9e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 CEG40808.1 - 1.6e-05 24.3 0.0 0.049 12.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEG40808.1 - 5e-05 23.0 0.0 0.00021 21.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CEG40808.1 - 0.00022 20.2 0.0 2.4 6.9 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 CEG40808.1 - 0.0013 17.8 0.6 0.12 11.4 0.6 2.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CEG40808.1 - 0.0052 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEG40808.1 - 0.01 16.4 0.1 0.059 13.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CEG40808.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 CEG40808.1 - 0.087 11.9 0.2 0.4 9.7 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 CEG40808.1 - 0.09 12.8 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding PIG-P PF08510.12 CEG40809.1 - 2.1e-31 108.4 1.4 3.2e-31 107.8 1.4 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CEG40809.1 - 0.0029 17.9 9.7 0.0039 17.5 8.5 1.8 1 1 1 2 2 2 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF3638 PF12340.8 CEG40810.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) 5-nucleotidase PF06189.12 CEG40812.1 - 0.1 11.5 0.0 6.8 5.5 0.0 2.3 2 1 0 2 2 2 0 5'-nucleotidase Mcl1_mid PF12341.8 CEG40813.1 - 7e-54 183.2 0.0 1.8e-53 181.8 0.0 1.7 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CEG40813.1 - 6.2e-05 23.2 0.0 2.1 8.7 0.0 3.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG40813.1 - 0.0026 18.6 0.3 29 5.7 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Hira PF07569.11 CEG40813.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split ABC1 PF03109.16 CEG40828.1 - 4.3e-36 123.7 0.0 7.9e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CEG40828.1 - 0.0024 17.3 0.2 0.0038 16.6 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CEG40828.1 - 0.074 13.0 0.1 0.47 10.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1394 PF07159.12 CEG40829.1 - 1.5e-51 175.5 3.7 2e-51 175.0 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) AlkA_N PF06029.11 CEG40829.1 - 0.06 13.6 0.1 0.16 12.2 0.1 1.7 1 1 0 1 1 1 0 AlkA N-terminal domain IU_nuc_hydro PF01156.19 CEG40830.1 - 7.8e-71 239.1 0.2 8.7e-71 239.0 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2004 PF09406.10 CEG40830.1 - 0.046 14.1 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Methyltransf_23 PF13489.6 CEG40831.1 - 1.4e-13 51.0 0.0 2.1e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG40831.1 - 5e-10 39.9 0.0 1.3e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG40831.1 - 1.4e-09 38.5 0.0 2.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG40831.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG40831.1 - 2e-06 28.3 0.0 4.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG40831.1 - 0.0052 16.3 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 CEG40831.1 - 0.0065 15.6 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF4599 PF15371.6 CEG40831.1 - 0.059 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Methyltransf_4 PF02390.17 CEG40831.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase SGL PF08450.12 CEG40832.1 - 1.9e-16 60.4 0.0 2.5e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CEG40832.1 - 4.3e-07 29.6 0.1 0.0086 16.1 0.0 4.3 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.16 CEG40832.1 - 1.2e-05 25.4 0.0 0.31 11.2 0.0 3.2 2 1 0 2 2 2 2 Strictosidine synthase Arylesterase PF01731.20 CEG40832.1 - 0.0008 19.6 0.0 0.27 11.4 0.0 2.9 3 0 0 3 3 3 2 Arylesterase Ldl_recept_b PF00058.17 CEG40832.1 - 0.018 15.5 0.0 0.093 13.2 0.0 2.2 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B PQQ_3 PF13570.6 CEG40832.1 - 0.046 14.2 4.6 4.4 7.9 2.3 3.6 3 2 0 3 3 3 0 PQQ-like domain Exo70 PF03081.15 CEG40833.1 - 3.4e-38 131.7 0.8 5.3e-38 131.1 0.8 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Sec34 PF04136.15 CEG40833.1 - 6.2e-05 22.9 1.4 0.00025 21.0 0.5 2.2 2 0 0 2 2 2 1 Sec34-like family COG6 PF06419.11 CEG40833.1 - 0.0025 16.1 11.3 0.0056 15.0 2.9 2.1 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 RabGAP-TBC PF00566.18 CEG40836.1 - 0.0035 17.0 0.2 0.0042 16.8 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Viral_DNA_bp PF00747.17 CEG40838.1 - 0.039 11.1 0.0 0.046 10.9 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein Asparaginase_2 PF01112.18 CEG40840.1 - 9.6e-76 254.7 0.2 1.2e-75 254.4 0.2 1.0 1 0 0 1 1 1 1 Asparaginase Metallophos PF00149.28 CEG40841.1 - 1.5e-39 136.7 0.1 2e-39 136.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DSPc PF00782.20 CEG40842.1 - 2e-32 111.8 0.0 3.2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG40842.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PX PF00787.24 CEG40843.1 - 1.3e-12 47.7 0.1 1.9e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 PX domain Beach PF02138.18 CEG40843.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Myosin_head PF00063.21 CEG40844.1 - 1.9e-202 674.2 3.3 2.7e-202 673.6 3.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 CEG40844.1 - 1.1e-18 67.6 0.2 7.8e-10 39.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CEG40844.1 - 2.4e-15 56.2 0.3 0.068 13.6 0.0 6.2 6 0 0 6 6 5 4 Ankyrin repeat Ank_3 PF13606.6 CEG40844.1 - 1.3e-13 49.8 0.0 0.076 13.6 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CEG40844.1 - 2.3e-12 47.2 0.3 0.055 14.1 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG40844.1 - 8.1e-11 42.0 0.9 0.00071 19.8 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 CEG40844.1 - 3.9e-05 24.1 0.7 0.00024 21.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CEG40844.1 - 0.0017 18.9 0.1 0.0061 17.1 0.1 2.0 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 CEG40844.1 - 0.0018 17.6 0.0 0.0051 16.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 CEG40844.1 - 0.007 16.7 0.7 0.13 12.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CEG40844.1 - 0.049 13.9 0.6 0.5 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CEG40844.1 - 0.091 12.8 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_6 PF12774.7 CEG40844.1 - 0.097 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 CEG40844.1 - 0.14 11.9 0.0 22 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG40844.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IQ PF00612.27 CEG40844.1 - 1 9.3 14.4 0.23 11.4 3.0 3.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif Dimer_Tnp_hAT PF05699.14 CEG40845.1 - 3.4e-11 42.8 1.4 4.1e-11 42.5 0.2 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF1160 PF06648.11 CEG40845.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Aldedh PF00171.22 CEG40847.1 - 8.9e-130 433.3 0.0 1.5e-129 432.6 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MAD PF05557.13 CEG40847.1 - 3e-20 72.2 82.4 5.4e-18 64.7 82.3 3.2 1 1 0 1 1 1 1 Mitotic checkpoint protein Dynactin_p62 PF05502.13 CEG40848.1 - 5.1e-06 25.5 5.5 0.0025 16.7 2.5 2.9 1 1 1 2 2 2 2 Dynactin p62 family LIM PF00412.22 CEG40848.1 - 2.1 8.7 5.9 1 9.6 3.3 1.8 2 0 0 2 2 2 0 LIM domain Methyltr_RsmB-F PF01189.17 CEG40849.1 - 2.6e-35 121.9 0.0 2.5e-33 115.4 0.0 2.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CEG40849.1 - 0.0041 17.2 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase zf-met PF12874.7 CEG40849.1 - 0.15 12.5 0.1 0.6 10.6 0.1 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type C2 PF00168.30 CEG40852.1 - 0.00053 20.2 0.2 0.0011 19.2 0.2 1.5 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 CEG40853.1 - 2e-13 50.5 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain PLAC8 PF04749.17 CEG40853.1 - 9.1e-07 29.8 0.2 2.3e-06 28.5 0.1 1.7 2 0 0 2 2 2 1 PLAC8 family IGPD PF00475.18 CEG40853.1 - 0.14 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase DUF4758 PF15950.5 CEG40854.1 - 0.034 14.5 2.5 0.12 12.7 2.5 1.9 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein SDA1 PF05285.12 CEG40854.1 - 2.5 7.4 5.5 3.9 6.8 5.5 1.1 1 0 0 1 1 1 0 SDA1 Ctr PF04145.15 CEG40856.1 - 2.4e-17 64.0 5.1 4.9e-17 62.9 5.1 1.5 1 1 0 1 1 1 1 Ctr copper transporter family YHS PF04945.13 CEG40856.1 - 0.0026 17.8 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 YHS domain PAAR_motif PF05488.13 CEG40856.1 - 0.098 12.8 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 PAAR motif DUF2417 PF10329.9 CEG40856.1 - 1 8.8 4.1 0.3 10.5 0.2 1.8 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Ctr PF04145.15 CEG40857.1 - 0.00074 20.2 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family MA3 PF02847.17 CEG40858.1 - 2.7e-44 149.8 0.0 5.5e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 MA3 domain Peptidase_M22 PF00814.25 CEG40860.1 - 2.4e-78 263.6 0.0 3.8e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family SPT2 PF08243.11 CEG40860.1 - 2.3e-15 57.1 10.6 8.5e-15 55.2 10.6 2.0 1 0 0 1 1 1 1 SPT2 chromatin protein Med26 PF08711.11 CEG40860.1 - 5.9e-09 35.8 1.5 1.5e-08 34.5 1.5 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SAM_1 PF00536.30 CEG40860.1 - 1.2e-07 32.1 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG40860.1 - 0.00029 20.9 0.0 0.00077 19.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CxC6 PF18721.1 CEG40861.1 - 2.2 8.6 8.3 5.6 7.3 0.2 2.9 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Abhydrolase_1 PF00561.20 CEG40862.1 - 8.8e-29 100.9 0.0 1.5e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG40862.1 - 4.5e-12 45.8 0.0 7.5e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CEG40862.1 - 3.8e-05 23.7 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 CEG40862.1 - 0.0003 21.5 0.0 0.00043 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 CEG40862.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family SpoU_methylase PF00588.19 CEG40863.1 - 1.5e-16 60.9 0.0 2.5e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF5598 PF18127.1 CEG40863.1 - 0.061 13.8 0.4 0.13 12.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) efb-c PF12199.8 CEG40863.1 - 2 8.5 5.0 0.89 9.7 0.2 2.5 3 0 0 3 3 3 0 Extracellular fibrinogen binding protein C terminal Ank_2 PF12796.7 CEG40864.1 - 1.5e-11 44.7 0.3 7.6e-09 36.0 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEG40864.1 - 1.1e-10 41.5 2.6 0.00032 21.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CEG40864.1 - 3e-10 39.4 0.9 7.7e-05 22.8 0.0 5.1 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CEG40864.1 - 1.5e-09 37.9 3.9 9.2e-06 25.8 0.1 4.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG40864.1 - 2.2e-09 37.6 0.1 6.3e-05 23.4 0.1 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Peptidase_C97 PF05903.14 CEG40865.1 - 2.6e-39 134.5 0.0 4.4e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 CEG40865.1 - 5.1e-12 45.6 3.1 8.6e-12 44.9 3.1 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C69 PF03577.15 CEG40866.1 - 1.1e-42 146.4 1.0 4e-42 144.6 1.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 FlgN PF05130.12 CEG40868.1 - 0.087 13.3 3.3 2.3 8.7 1.1 2.8 2 1 0 2 2 2 0 FlgN protein hNIFK_binding PF12196.8 CEG40868.1 - 0.17 11.4 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Pkinase PF00069.25 CEG40869.1 - 1.3e-77 260.8 0.0 1.5e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40869.1 - 1.6e-31 109.5 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG40869.1 - 1e-05 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEG40869.1 - 0.00015 21.2 0.0 0.00065 19.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CEG40869.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CEG40869.1 - 0.013 15.4 0.5 0.052 13.5 0.1 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG40869.1 - 0.055 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RAMA PF18755.1 CEG40872.1 - 1.9e-13 50.8 0.8 7.8e-13 48.8 0.0 2.6 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated PHD PF00628.29 CEG40872.1 - 1.2e-07 31.4 7.6 3.4e-07 30.1 7.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CEG40872.1 - 0.0063 16.4 1.4 0.018 14.9 1.4 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CEG40872.1 - 0.092 12.9 5.2 0.8 9.8 5.2 2.8 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 CEG40872.1 - 0.1 13.0 1.2 0.26 11.6 1.2 1.7 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 CEG40872.1 - 0.23 11.0 3.7 0.6 9.7 3.7 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CEG40872.1 - 2.5 8.1 8.9 0.8 9.7 5.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_S10 PF00450.22 CEG40875.1 - 5.1e-97 325.9 3.8 6.8e-97 325.5 3.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase TMEM51 PF15345.6 CEG40875.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM154 PF15102.6 CEG40875.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.16 CEG40875.1 - 0.059 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.11 CEG40875.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Pkinase PF00069.25 CEG40876.1 - 2.1e-68 230.6 0.0 2.4e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40876.1 - 2.5e-33 115.5 0.0 7.5e-33 113.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG40876.1 - 2.3e-07 30.1 2.1 4.3e-07 29.2 2.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEG40876.1 - 0.00028 20.3 0.1 0.00048 19.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG40876.1 - 0.0088 15.4 2.1 0.016 14.6 2.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEG40876.1 - 0.016 14.8 0.6 3.5 7.2 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEG40876.1 - 0.087 11.6 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CEG40876.1 - 0.09 12.7 0.4 1.4 8.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FeoB_N PF02421.18 CEG40876.1 - 0.098 12.2 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B UBA PF00627.31 CEG40877.1 - 2.7e-30 103.8 1.6 2.7e-15 55.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 CEG40877.1 - 2.1e-24 85.0 10.9 2.1e-24 85.0 10.9 2.2 2 1 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 CEG40877.1 - 9.9e-23 79.7 2.3 1.3e-22 79.3 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CEG40877.1 - 1.6e-06 27.9 1.8 8.6e-06 25.5 1.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.9 CEG40877.1 - 0.0013 18.5 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain Ubiquitin_5 PF18037.1 CEG40877.1 - 0.0099 16.2 0.1 0.024 15.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain RAP1 PF07218.11 CEG40877.1 - 0.01 14.2 5.3 0.014 13.7 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1421 PF07223.11 CEG40877.1 - 0.012 15.4 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA_3 PF09288.10 CEG40877.1 - 0.012 15.3 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2407 PF10302.9 CEG40877.1 - 0.023 15.2 0.0 0.068 13.7 0.0 1.9 2 0 0 2 2 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 CEG40877.1 - 0.026 14.2 0.0 0.32 10.7 0.0 2.8 3 0 0 3 3 3 0 CUE domain Rad60-SLD_2 PF13881.6 CEG40877.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3135 PF11333.8 CEG40877.1 - 0.088 13.1 0.2 0.088 13.1 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) Ubiquitin_2 PF14560.6 CEG40877.1 - 0.2 12.1 0.2 0.63 10.5 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain DUF3306 PF11748.8 CEG40877.1 - 0.3 11.9 4.4 0.16 12.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MBOAT PF03062.19 CEG40878.1 - 2.5e-40 138.9 4.1 2.7e-40 138.8 3.2 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF5325 PF17259.2 CEG40879.1 - 0.4 10.6 3.1 0.7 9.8 3.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) PX PF00787.24 CEG40880.1 - 2.8e-10 40.2 0.8 1.7e-09 37.7 0.2 2.6 2 0 0 2 2 2 1 PX domain Metallophos PF00149.28 CEG40881.1 - 2.5e-07 31.4 0.1 1e-06 29.4 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 CEG40881.1 - 0.0064 15.8 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Abhydro_lipase PF04083.16 CEG40883.1 - 3.9e-18 64.8 0.1 8.5e-18 63.7 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEG40883.1 - 2e-11 44.0 0.2 3.6e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG40883.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_pol_Rpb5_N PF03871.14 CEG40883.1 - 0.081 13.5 0.1 0.23 12.1 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain AAA PF00004.29 CEG40886.1 - 1.3e-11 45.1 0.0 2.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG40886.1 - 1.1e-05 25.7 0.0 0.00014 22.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG40886.1 - 1.1e-05 26.0 0.0 4.4e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEG40886.1 - 1.2e-05 25.4 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG40886.1 - 2.1e-05 24.7 0.0 9.3e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CEG40886.1 - 7.4e-05 22.8 0.0 0.0025 17.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 CEG40886.1 - 0.0001 22.1 0.9 0.033 13.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CEG40886.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEG40886.1 - 0.0005 20.5 0.0 0.0019 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEG40886.1 - 0.00085 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CEG40886.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 CEG40886.1 - 0.0038 17.0 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEG40886.1 - 0.0039 17.4 0.0 0.024 14.9 0.0 2.4 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CEG40886.1 - 0.0046 17.3 0.3 0.05 14.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase ABC_tran PF00005.27 CEG40886.1 - 0.0078 16.7 0.2 0.056 14.0 0.0 2.6 2 0 0 2 2 1 1 ABC transporter AAA_17 PF13207.6 CEG40886.1 - 0.011 16.2 0.0 0.038 14.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain RRP7 PF12923.7 CEG40886.1 - 0.012 15.7 2.3 0.033 14.3 2.3 1.7 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DNA_pol3_delta PF06144.13 CEG40886.1 - 0.02 14.7 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NB-ARC PF00931.22 CEG40886.1 - 0.021 14.0 0.1 0.32 10.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 CEG40886.1 - 0.024 14.2 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 CEG40886.1 - 0.028 13.8 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SSE PF00437.20 CEG40886.1 - 0.029 13.4 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 CEG40886.1 - 0.043 13.4 0.0 0.99 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_assoc_2 PF16193.5 CEG40886.1 - 0.052 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_7 PF12775.7 CEG40886.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IBD PF10416.9 CEG40886.1 - 0.082 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Viral_helicase1 PF01443.18 CEG40886.1 - 0.086 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CEG40886.1 - 0.11 12.3 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 CEG40886.1 - 0.12 12.1 3.6 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEG40886.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoD_N PF16655.5 CEG40887.1 - 0.035 14.6 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain RXLR PF16810.5 CEG40888.1 - 0.086 13.3 0.5 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity AAA_31 PF13614.6 CEG40891.1 - 7.4e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 CEG40891.1 - 0.0001 21.8 0.0 0.00027 20.5 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 CEG40891.1 - 0.033 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ CbiA PF01656.23 CEG40891.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1388 PF07142.12 CEG40892.1 - 0.085 12.8 0.4 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) CH PF00307.31 CEG40893.1 - 5.6e-15 55.5 0.0 1.4e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain AroM PF07302.11 CEG40893.1 - 0.019 14.3 0.4 0.067 12.6 0.1 2.0 2 0 0 2 2 2 0 AroM protein WD40 PF00400.32 CEG40894.1 - 1.6e-21 76.2 4.9 1.2e-07 32.3 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40894.1 - 3.3e-06 27.3 0.1 0.61 10.4 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG40894.1 - 0.0014 18.1 1.7 0.0023 17.3 0.1 2.0 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 CEG40894.1 - 0.026 13.2 0.0 0.045 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PfkB PF00294.24 CEG40895.1 - 8.4e-63 212.5 1.1 1.1e-62 212.0 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2475 PF10629.9 CEG40896.1 - 0.007 16.6 2.2 9.7 6.5 0.1 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2475) Nudc_N PF14050.6 CEG40896.1 - 0.13 12.3 0.1 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Sec1 PF00995.23 CEG40897.1 - 8.6e-71 239.9 1.7 9.6e-71 239.7 1.7 1.0 1 0 0 1 1 1 1 Sec1 family DUF3399 PF11879.8 CEG40897.1 - 0.0024 18.2 1.7 0.0092 16.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) DARPP-32 PF05395.12 CEG40897.1 - 0.049 13.9 0.5 6 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 PALP PF00291.25 CEG40898.1 - 3.8e-62 210.3 0.0 4.7e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CEG40898.1 - 2.7e-15 56.6 2.4 4e-09 36.8 0.1 3.7 3 1 0 3 3 3 2 CBS domain LysM PF01476.20 CEG40900.1 - 2.9e-31 107.3 0.0 1.2e-09 38.0 0.0 4.2 4 0 0 4 4 4 4 LysM domain Ctr PF04145.15 CEG40901.1 - 1.6e-22 80.7 3.4 2.9e-22 79.9 3.4 1.4 1 0 0 1 1 1 1 Ctr copper transporter family UPF0220 PF05255.11 CEG40901.1 - 0.0036 16.9 3.4 0.012 15.2 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0220) zf-Di19 PF05605.12 CEG40901.1 - 0.0043 17.3 0.4 3.9 7.8 0.1 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding PetM PF08041.11 CEG40901.1 - 0.011 15.3 1.9 0.011 15.3 1.9 2.2 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 Zn-ribbon_8 PF09723.10 CEG40901.1 - 0.023 14.8 0.4 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 CEG40901.1 - 0.028 14.3 0.7 6.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG40901.1 - 0.072 13.0 0.5 7.1 6.6 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 OrfB_Zn_ribbon PF07282.11 CEG40901.1 - 0.093 12.7 0.6 2.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.6 CEG40901.1 - 0.12 12.2 1.0 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn-C2H2_12 PF18112.1 CEG40901.1 - 0.33 11.4 1.2 12 6.5 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ribbon_3 PF13248.6 CEG40901.1 - 3.7 7.1 6.0 7.6 6.1 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Ctr PF04145.15 CEG40902.1 - 2.9e-15 57.1 14.6 2.8e-08 34.5 11.2 2.3 1 1 1 2 2 2 2 Ctr copper transporter family HMA PF00403.26 CEG40902.1 - 4.9e-08 33.3 0.1 4.9e-08 33.3 0.1 1.7 2 0 0 2 2 2 1 Heavy-metal-associated domain zf-C2H2_3 PF13878.6 CEG40902.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO TF_Zn_Ribbon PF08271.12 CEG40902.1 - 2 8.0 5.6 0.57 9.7 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Rad10 PF03834.14 CEG40903.1 - 6.5e-39 132.5 0.1 1e-38 131.8 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CEG40903.1 - 6.2e-06 26.7 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 CEG40903.1 - 0.00023 20.8 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 CEG40903.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif RMI1_N PF08585.12 CEG40904.1 - 4.8e-23 82.1 0.0 3.7e-16 59.6 0.0 2.5 1 1 1 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 CEG40904.1 - 5.4e-23 81.4 0.0 8.9e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold S-AdoMet_synt_C PF02773.16 CEG40905.1 - 4.7e-64 214.5 1.0 7.1e-64 213.9 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CEG40905.1 - 1.1e-47 161.2 0.1 2.5e-47 160.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CEG40905.1 - 9.3e-44 148.2 1.6 1.2e-43 147.8 0.3 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Methyltransf_31 PF13847.6 CEG40906.1 - 1.5e-08 34.6 0.1 2.4e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEG40906.1 - 8.1e-08 32.4 5.8 5.7e-07 29.6 2.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain TRM13 PF05206.14 CEG40906.1 - 2.4e-07 30.5 0.8 3.7e-05 23.4 0.5 2.9 1 1 1 2 2 2 1 Methyltransferase TRM13 Methyltransf_25 PF13649.6 CEG40906.1 - 1.1e-06 29.3 0.1 2.5e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG40906.1 - 6.2e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CEG40906.1 - 9.6e-05 21.9 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 CEG40906.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 CEG40906.1 - 0.00048 20.8 0.1 0.0014 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 CEG40906.1 - 0.12 12.2 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase PCMT PF01135.19 CEG40906.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-TRM13_CCCH PF11722.8 CEG40906.1 - 0.17 11.7 1.0 0.65 9.8 1.0 2.1 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein zf-C3HC4_3 PF13920.6 CEG40907.1 - 0.00022 21.0 1.3 0.00022 21.0 1.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG40907.1 - 0.00054 19.8 2.2 0.00054 19.8 2.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CEG40907.1 - 0.0073 16.1 2.1 0.0073 16.1 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG40907.1 - 0.01 15.7 2.4 0.01 15.7 2.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG40907.1 - 0.98 9.8 9.2 0.043 14.2 3.1 2.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 CEG40907.1 - 2.8 8.0 7.8 0.31 11.0 1.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Pyr_redox_2 PF07992.14 CEG40908.1 - 0.00011 21.5 0.0 0.00029 20.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG40908.1 - 0.0011 18.3 0.1 0.0021 17.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG40908.1 - 0.0013 17.5 0.1 0.0028 16.4 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CEG40908.1 - 0.0022 17.1 0.1 0.0046 16.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEG40908.1 - 0.0076 15.9 0.8 0.027 14.1 0.5 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEG40908.1 - 0.013 14.8 0.7 0.044 13.0 0.1 2.2 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 CEG40908.1 - 0.026 13.8 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CEG40908.1 - 0.049 14.2 0.1 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEG40908.1 - 0.12 11.7 0.2 0.28 10.5 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GLTSCR1 PF15249.6 CEG40908.1 - 0.17 12.3 1.0 22 5.6 0.0 3.3 3 0 0 3 3 3 0 Conserved region of unknown function on GLTSCR protein FTA4 PF13093.6 CEG40909.1 - 0.029 14.3 0.3 0.046 13.6 0.3 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HI0933_like PF03486.14 CEG40910.1 - 0.025 13.3 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 HI0933-like protein Bombinin PF05298.11 CEG40911.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Bombinin Shugoshin_C PF07557.11 CEG40912.1 - 8.7e-10 38.2 11.1 2e-06 27.4 1.3 2.6 2 0 0 2 2 2 2 Shugoshin C terminus UvrD-helicase PF00580.21 CEG40912.1 - 0.082 12.4 1.0 0.093 12.2 1.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CHASE6_C PF17150.4 CEG40912.1 - 0.083 13.6 0.8 1.1 10.0 0.0 2.6 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain ZapB PF06005.12 CEG40912.1 - 0.43 11.0 5.4 0.98 9.9 3.7 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 CEG40913.1 - 2.4e-25 89.4 0.1 2.8e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG40913.1 - 1.1e-12 47.8 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2556 PF10831.8 CEG40913.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Trans_reg_C PF00486.28 CEG40914.1 - 0.098 12.8 0.8 0.15 12.2 0.3 1.7 2 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal YjgF_endoribonc PF14588.6 CEG40915.1 - 1e-18 67.9 0.0 1.3e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 CEG40915.1 - 3.3e-08 33.6 0.0 5.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP UPF0640 PF15114.6 CEG40916.1 - 0.001 18.8 0.1 0.0017 18.2 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0640 NT5C PF06941.12 CEG40917.1 - 1.1e-09 38.5 0.1 2.1e-09 37.5 0.1 1.5 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Alba PF01918.21 CEG40917.1 - 1.2e-06 28.2 0.4 3.1e-06 26.9 0.4 1.6 1 0 0 1 1 1 1 Alba Homez PF11569.8 CEG40917.1 - 0.35 10.4 1.7 3.3 7.2 0.2 2.9 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez PX PF00787.24 CEG40918.1 - 2.8e-20 72.4 0.0 4.7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 PX domain LAMTOR PF15454.6 CEG40918.1 - 0.013 16.1 0.1 0.25 12.0 0.0 2.5 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Biotin_carb_N PF00289.22 CEG40918.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain DUF4354 PF14263.6 CEG40919.1 - 0.014 15.2 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF16 PF01519.16 CEG40919.1 - 0.029 14.9 0.1 0.029 14.9 0.1 5.7 3 1 1 4 4 4 0 Protein of unknown function DUF16 DUF1192 PF06698.11 CEG40919.1 - 0.035 14.2 1.1 0.32 11.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) MRFAP1 PF15155.6 CEG40919.1 - 1.4 9.5 10.6 0.12 12.9 2.9 3.0 2 1 1 3 3 3 0 MORF4 family-associated protein1 DUF99 PF01949.16 CEG40919.1 - 7.3 6.0 6.8 0.87 9.0 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF99 PI3_PI4_kinase PF00454.27 CEG40920.1 - 7.6e-52 176.6 0.0 1.4e-51 175.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CEG40920.1 - 1.6e-35 123.0 2.6 5.7e-35 121.2 2.6 2.0 1 1 0 1 1 1 1 FAT domain UME PF08064.13 CEG40920.1 - 7.4e-18 64.4 0.7 2.5e-15 56.2 0.0 3.7 3 0 0 3 3 3 1 UME (NUC010) domain TPR_19 PF14559.6 CEG40920.1 - 0.016 15.7 1.3 0.94 10.0 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CEG40920.1 - 0.12 12.5 2.8 0.27 11.3 0.1 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3385 PF11865.8 CEG40920.1 - 0.13 12.2 0.1 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_2 PF07719.17 CEG40920.1 - 0.24 11.6 5.4 1.2 9.5 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40920.1 - 0.53 10.0 3.5 8.9 6.1 1.4 3.0 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 CEG40920.1 - 1.5 9.0 3.7 0.98 9.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40920.1 - 3.6 7.5 7.0 0.79 9.7 0.8 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.16 CEG40921.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SUI1 PF01253.22 CEG40922.1 - 5.5e-23 81.3 0.8 9.1e-23 80.6 0.5 1.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF2997 PF11211.8 CEG40922.1 - 0.036 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) HELP PF03451.14 CEG40923.1 - 3.3e-57 190.2 0.8 3.3e-21 74.9 0.1 3.6 3 0 0 3 3 3 3 HELP motif WD40 PF00400.32 CEG40923.1 - 1.9e-56 186.7 92.8 0.0017 19.1 0.2 28.5 30 0 0 30 30 30 17 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40923.1 - 5e-28 97.2 4.5 0.00014 22.0 0.0 13.9 12 5 4 16 16 16 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG40923.1 - 1.8e-07 30.5 0.0 0.097 11.6 0.0 4.8 5 0 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 CEG40923.1 - 1e-05 24.8 0.0 0.0048 16.0 0.0 3.6 3 1 1 4 4 4 1 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 CEG40923.1 - 0.00065 18.6 0.1 0.73 8.5 0.0 3.6 2 1 0 3 3 3 2 Nup133 N terminal like eIF2A PF08662.11 CEG40923.1 - 0.0014 18.5 5.8 6.8 6.5 0.0 6.9 8 2 1 9 9 9 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEG40923.1 - 0.0031 16.9 6.1 1.1 8.5 0.0 5.9 7 0 0 7 7 7 1 WD40-like domain PD40 PF07676.12 CEG40923.1 - 0.053 13.5 0.1 22 5.2 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat EF-hand_8 PF13833.6 CEG40923.1 - 0.41 10.5 1.9 0.89 9.5 1.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF1279 PF06916.13 CEG40924.1 - 8.4e-05 23.0 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Sec3_C_2 PF15278.6 CEG40924.1 - 0.0069 16.7 8.0 0.073 13.4 0.9 2.3 1 1 1 2 2 2 2 Sec3 exocyst complex subunit Cnn_1N PF07989.11 CEG40924.1 - 0.0096 16.1 5.1 0.0096 16.1 5.1 2.2 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 Glyco_transf_41 PF13844.6 CEG40924.1 - 0.033 12.6 1.6 0.13 10.7 1.8 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 41 Fur_reg_FbpB PF13040.6 CEG40924.1 - 0.056 13.0 3.2 4 7.1 0.2 2.7 2 0 0 2 2 2 0 Fur-regulated basic protein B Clr5 PF14420.6 CEG40924.1 - 0.14 12.4 0.8 0.35 11.1 0.2 1.8 2 0 0 2 2 2 0 Clr5 domain CLN3 PF02487.17 CEG40924.1 - 0.15 11.1 0.5 0.21 10.6 0.5 1.2 1 0 0 1 1 1 0 CLN3 protein RNA_pol_Rbc25 PF08292.12 CEG40924.1 - 0.27 11.4 4.2 1.8 8.8 4.2 2.0 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 SSXT PF05030.12 CEG40924.1 - 1.1 8.9 11.7 1.4 8.6 0.5 3.4 2 1 1 3 3 3 0 SSXT protein (N-terminal region) TetR_C_23 PF17931.1 CEG40924.1 - 3.1 7.9 8.1 1.6 8.8 1.1 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GUN4_N PF16416.5 CEG40924.1 - 5.5 7.0 7.3 6.1 6.9 1.3 2.5 2 1 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal DUF2547 PF10818.8 CEG40924.1 - 6.6 7.7 6.5 13 6.8 5.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) HIT PF01230.23 CEG40927.1 - 2.3e-26 92.4 0.1 2.9e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CEG40927.1 - 3.6e-19 69.3 0.1 4.6e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PCDO_beta_N PF12391.8 CEG40927.1 - 0.042 13.5 0.5 0.08 12.6 0.5 1.4 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal HD PF01966.22 CEG40928.1 - 2.4e-07 31.0 0.1 4.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 HD domain T_hemolysin PF12261.8 CEG40928.1 - 0.00063 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Thermostable hemolysin HDOD PF08668.12 CEG40928.1 - 0.022 14.2 0.4 0.042 13.3 0.1 1.6 2 0 0 2 2 2 0 HDOD domain KAP PF05804.12 CEG40929.1 - 1.5e-104 350.6 22.8 1.9e-54 185.0 1.4 2.0 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) DUF3967 PF13152.6 CEG40929.1 - 1.1 9.1 4.0 28 4.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) DUF4658 PF15555.6 CEG40930.1 - 0.028 14.5 0.2 0.065 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) T3SS_needle_E PF08988.10 CEG40931.1 - 0.15 12.2 2.8 0.3 11.3 1.3 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Trp_syntA PF00290.20 CEG40932.1 - 1.4e-47 161.8 0.0 1.6e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PA PF02225.22 CEG40932.1 - 0.012 15.7 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 PA domain His_biosynth PF00977.21 CEG40932.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_1 PF00515.28 CEG40933.1 - 8.3e-05 22.2 2.5 0.15 12.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG40933.1 - 0.00036 20.4 0.2 0.55 10.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40933.1 - 0.003 18.2 2.2 3 8.6 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Syntaxin PF00804.25 CEG40933.1 - 0.093 12.4 0.2 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Syntaxin TPR_11 PF13414.6 CEG40933.1 - 0.15 11.8 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 CEG40933.1 - 0.16 12.7 2.0 32 5.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.23 CEG40934.1 - 1.3e-49 168.8 0.0 2.8e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG40934.1 - 1.1e-15 57.9 0.0 2.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG40934.1 - 3.1e-09 37.1 0.0 3.8e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG40934.1 - 1.4e-05 25.0 0.0 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CEG40934.1 - 0.0035 16.6 0.1 0.0086 15.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) HDA2-3 PF11496.8 CEG40934.1 - 0.0062 15.7 0.4 0.02 14.1 0.1 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PPR_2 PF13041.6 CEG40935.1 - 4.9e-25 87.5 2.7 8.1e-08 32.3 0.0 9.0 7 2 2 9 9 9 4 PPR repeat family PPR_3 PF13812.6 CEG40935.1 - 2e-18 66.2 2.9 4.6e-05 23.4 0.0 8.6 5 2 3 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.20 CEG40935.1 - 4.6e-17 61.0 2.4 0.0069 16.6 0.0 10.4 11 0 0 11 11 11 2 PPR repeat PPR_long PF17177.4 CEG40935.1 - 1.1e-11 44.5 1.4 2.6e-05 23.7 0.0 4.9 4 1 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEG40935.1 - 2.3e-06 27.2 0.0 1.3 8.8 0.0 6.2 6 0 0 6 6 6 2 PPR repeat Kinesin PF00225.23 CEG40936.1 - 1.1e-110 369.6 0.2 1.1e-110 369.6 0.2 2.5 3 1 0 3 3 3 1 Kinesin motor domain MFS_1 PF07690.16 CEG40936.1 - 2.4e-46 158.3 47.4 6.6e-45 153.6 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Microtub_bd PF16796.5 CEG40936.1 - 2e-26 92.7 1.5 3.1e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3926 PF13080.6 CEG40936.1 - 0.12 12.3 0.3 0.55 10.2 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) AAA_22 PF13401.6 CEG40936.1 - 0.42 10.9 6.6 21 5.4 0.0 3.5 2 1 1 3 3 3 0 AAA domain TolA_bind_tri PF16331.5 CEG40936.1 - 4.3 7.5 22.9 9.7 6.4 1.1 5.0 3 2 0 3 3 3 0 TolA binding protein trimerisation Wzy_C PF04932.15 CEG40936.1 - 5.2 6.7 11.0 0.098 12.3 0.6 2.6 2 1 0 2 2 2 0 O-Antigen ligase malic PF00390.19 CEG40938.1 - 0.047 13.5 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain PGAP1 PF07819.13 CEG40939.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 CEG40939.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1 PF00133.22 CEG40940.1 - 1.8e-167 558.2 0.0 2.5e-167 557.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEG40940.1 - 1.5e-27 96.4 0.0 3.3e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEG40940.1 - 8.7e-19 67.5 0.2 9e-10 37.8 0.0 3.8 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEG40940.1 - 0.00078 19.0 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 CEG40940.1 - 0.0025 17.6 1.8 0.0057 16.5 1.8 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 CEG40940.1 - 0.02 14.2 0.0 0.73 9.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PH PF00169.29 CEG40941.1 - 1.4e-06 28.8 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Vps16_C PF04840.12 CEG40941.1 - 0.00038 19.6 0.6 0.0048 16.0 0.1 2.2 2 0 0 2 2 2 1 Vps16, C-terminal region PH_9 PF15410.6 CEG40941.1 - 0.029 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_C69 PF03577.15 CEG40942.1 - 6e-47 160.5 0.0 1.4e-46 159.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family C69 ArsB PF02040.15 CEG40942.1 - 0.27 10.5 0.7 5.8 6.1 0.4 2.1 2 0 0 2 2 2 0 Arsenical pump membrane protein ThiF PF00899.21 CEG40943.1 - 5.1e-25 88.2 0.0 1.1e-24 87.1 0.0 1.6 1 1 0 1 1 1 1 ThiF family DpnII PF04556.12 CEG40943.1 - 0.2 10.9 0.5 0.6 9.4 0.1 1.9 2 0 0 2 2 2 0 DpnII restriction endonuclease SET PF00856.28 CEG40944.1 - 1.4e-12 48.3 5.6 2.4e-11 44.3 5.6 2.7 1 1 0 1 1 1 1 SET domain Sin_N PF04801.13 CEG40944.1 - 0.005 16.1 4.0 0.008 15.4 4.0 1.4 1 0 0 1 1 1 1 Sin-like protein conserved region Myticin-prepro PF10690.9 CEG40944.1 - 0.39 11.0 6.7 1.9 8.8 2.3 2.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel PRP1_N PF06424.12 CEG40944.1 - 1.5 9.2 6.9 25 5.2 0.0 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Fz PF01392.22 CEG40945.1 - 7.4 7.2 13.4 0.054 14.1 3.0 2.6 2 2 0 2 2 2 0 Fz domain SET PF00856.28 CEG40946.1 - 4.2e-15 56.5 2.6 3.5e-13 50.3 2.6 2.6 1 1 0 1 1 1 1 SET domain Iso_dh PF00180.20 CEG40948.1 - 8.4e-74 248.8 0.0 9.8e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 CEG40948.1 - 0.024 15.3 0.4 0.24 12.1 0.2 2.3 2 0 0 2 2 2 0 Phenylalanine zipper HLH PF00010.26 CEG40949.1 - 7.6e-06 25.8 2.4 8.5e-06 25.6 1.2 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 CEG40949.1 - 0.027 14.7 1.1 0.027 14.7 1.1 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ebp2 PF05890.12 CEG40949.1 - 0.4 10.2 4.0 0.75 9.3 1.5 2.0 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 ING PF12998.7 CEG40951.1 - 1.4e-18 67.3 2.9 3.1e-18 66.2 2.9 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding TIM21 PF08294.11 CEG40951.1 - 0.061 13.2 0.3 0.084 12.7 0.3 1.3 1 0 0 1 1 1 0 TIM21 Kelch_6 PF13964.6 CEG40952.1 - 7e-10 38.8 2.3 0.044 14.1 0.0 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 CEG40952.1 - 5.9e-09 35.4 0.1 0.092 12.4 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 CEG40952.1 - 6.9e-09 35.5 0.7 0.71 9.9 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CEG40952.1 - 0.00011 22.1 8.0 1.1 9.3 0.0 6.3 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 CEG40952.1 - 0.001 19.0 6.9 0.26 11.3 0.0 4.7 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF4381 PF14316.6 CEG40952.1 - 0.089 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EB PF01683.18 CEG40952.1 - 0.39 11.0 4.1 0.86 9.9 4.1 1.5 1 0 0 1 1 1 0 EB module Kelch_3 PF13415.6 CEG40952.1 - 7 7.1 17.0 1.3 9.3 0.1 6.6 9 1 0 9 9 9 0 Galactose oxidase, central domain Tfb4 PF03850.14 CEG40953.1 - 3.9e-50 170.9 0.2 5e-50 170.5 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF3155 PF11352.8 CEG40953.1 - 0.075 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) ATP-synt_DE_N PF02823.16 CEG40953.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_L27e PF01777.18 CEG40955.1 - 0.053 13.9 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L27e protein family CG-1 PF03859.16 CEG40957.1 - 2.6e-26 91.7 2.1 4.7e-26 90.9 0.2 2.4 2 0 0 2 2 2 1 CG-1 domain Ank_5 PF13857.6 CEG40957.1 - 8.7e-18 64.2 0.9 1.1e-10 41.6 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG40957.1 - 3.8e-10 40.2 0.4 1.6e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEG40957.1 - 4.6e-09 36.3 0.8 4.2e-06 27.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CEG40957.1 - 1.2e-07 32.1 0.8 5.4e-06 26.8 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG40957.1 - 1.3e-07 31.3 0.1 0.00029 21.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.27 CEG40957.1 - 0.0014 18.3 21.7 0.019 14.7 0.2 5.8 7 0 0 7 7 7 2 IQ calmodulin-binding motif CsiD PF08943.10 CEG40957.1 - 0.044 12.9 0.2 0.09 11.9 0.2 1.4 1 0 0 1 1 1 0 CsiD DUF4757 PF15949.5 CEG40957.1 - 0.21 12.1 5.5 0.095 13.2 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) MRP-L28 PF09812.9 CEG40958.1 - 0.0055 16.8 0.1 0.0068 16.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 ATP-grasp_4 PF13535.6 CEG40959.1 - 2.7e-26 92.1 0.0 1.8e-12 47.1 0.0 3.5 4 0 0 4 4 4 2 ATP-grasp domain ATP-grasp_3 PF02655.14 CEG40959.1 - 3.1e-15 56.6 0.1 4.1e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain LAL_C2 PF18603.1 CEG40959.1 - 6.9e-15 55.0 0.0 1.4e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 L-amino acid ligase C-terminal domain 2 GARS_A PF01071.19 CEG40959.1 - 2.2e-12 47.2 0.3 5.6e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 CEG40959.1 - 1e-10 41.5 0.0 0.0012 18.6 0.0 3.9 2 2 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 CEG40959.1 - 1.7e-06 27.7 0.0 0.0075 15.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain UpxZ PF06603.11 CEG40959.1 - 0.15 12.3 0.0 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists tRNA-synt_2b PF00587.25 CEG40960.1 - 5e-35 121.1 0.0 7.8e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEG40960.1 - 1.5e-18 66.7 0.2 3.4e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CEG40960.1 - 3e-10 40.0 0.0 7.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CEG40960.1 - 5.9e-07 29.5 0.0 1.8e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 TGS domain DUF1712 PF08217.11 CEG40962.1 - 3.9e-14 52.1 3.1 4.5e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) Ceramidase PF05875.12 CEG40963.1 - 1.4e-64 218.1 15.1 1.6e-64 217.9 15.1 1.0 1 0 0 1 1 1 1 Ceramidase Bax1-I PF01027.20 CEG40963.1 - 0.18 11.6 12.5 0.1 12.4 9.1 2.1 1 1 2 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 PEN-2 PF10251.9 CEG40963.1 - 1.6 9.2 8.5 0.54 10.7 0.2 2.5 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Ceramidase PF05875.12 CEG40964.1 - 1.8e-63 214.5 15.6 2.1e-63 214.2 15.6 1.0 1 0 0 1 1 1 1 Ceramidase Bax1-I PF01027.20 CEG40964.1 - 0.0038 17.1 11.1 0.0075 16.1 9.8 2.1 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Aminoglyc_resit PF10706.9 CEG40964.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase DUF4131 PF13567.6 CEG40964.1 - 7.4 6.2 8.3 45 3.6 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.27 CEG40965.1 - 2.6e-26 91.4 1.4 1.6e-16 60.0 0.2 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein SPT_ssu-like PF11779.8 CEG40966.1 - 9.7e-11 41.1 4.4 1.4e-10 40.6 4.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like NLRC4_HD PF17889.1 CEG40967.1 - 9.6e-05 22.7 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 NLRC4 helical domain B9-C2 PF07162.11 CEG40968.1 - 7.6e-16 58.8 0.1 9.4e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Peptidase_A22B PF04258.13 CEG40969.1 - 1.2e-57 195.6 5.4 2e-57 194.9 5.4 1.3 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 CEG40969.1 - 4.2e-07 29.9 0.5 3.1e-06 27.1 0.2 2.4 2 0 0 2 2 2 1 PA domain EF-hand_7 PF13499.6 CEG40970.1 - 0.00088 19.7 0.1 0.0053 17.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG40970.1 - 0.0057 16.1 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG40970.1 - 0.013 15.4 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain Gly_acyl_tr_N PF06021.11 CEG40970.1 - 2.3 8.3 7.1 4.8 7.2 7.1 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Fib_alpha PF08702.10 CEG40970.1 - 3.5 7.8 11.5 2.3 8.4 8.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.17 CEG40971.1 - 0.0028 17.7 5.8 1.9 8.8 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40971.1 - 0.066 13.4 1.1 1.8 8.8 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40971.1 - 0.093 13.2 0.0 38 5.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BHD_2 PF10404.9 CEG40974.1 - 0.1 13.5 0.1 0.31 12.0 0.1 1.8 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Steroid_dh PF02544.16 CEG40976.1 - 3.5e-17 62.8 4.1 5.6e-17 62.1 3.8 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CEG40976.1 - 0.00023 21.5 1.3 0.00023 21.5 1.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase CrgA PF06781.12 CEG40976.1 - 0.062 13.4 2.8 1.6 8.9 0.1 2.9 2 1 0 2 2 2 0 Cell division protein CrgA DUF5408 PF17402.2 CEG40976.1 - 0.2 11.6 0.9 0.47 10.4 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) G10 PF01125.17 CEG40977.1 - 2e-53 180.1 5.6 5.6e-53 178.6 5.6 1.7 1 0 0 1 1 1 1 G10 protein WD40 PF00400.32 CEG40978.1 - 1e-16 61.0 11.8 0.0012 19.7 0.1 6.3 5 2 2 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG40978.1 - 7.5e-16 58.2 1.5 0.00065 20.0 0.0 5.2 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG40978.1 - 3.3e-10 40.1 0.0 4.8e-05 23.3 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEG40978.1 - 1.1e-07 31.2 2.4 4.5e-05 22.6 0.0 3.0 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CblD PF07434.11 CEG40978.1 - 0.05 12.5 0.1 0.082 11.8 0.1 1.3 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator PX PF00787.24 CEG40979.1 - 1.2e-08 34.9 3.3 1e-07 32.0 1.9 2.3 2 0 0 2 2 2 1 PX domain OTU PF02338.19 CEG40979.1 - 0.0018 18.8 1.0 0.33 11.5 0.4 3.1 2 1 0 2 2 2 2 OTU-like cysteine protease HECT_2 PF09814.9 CEG40980.1 - 3.1e-29 102.0 1.1 8.6e-29 100.5 1.0 1.6 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HEAT_2 PF13646.6 CEG40981.1 - 1.4e-35 121.5 9.7 9.2e-13 48.4 0.1 3.6 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 CEG40981.1 - 4e-19 67.3 0.4 0.0055 17.3 0.0 6.3 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 CEG40981.1 - 2.7e-08 33.4 1.5 0.86 10.0 0.0 5.7 7 0 0 7 7 7 2 HEAT repeat DUF3385 PF11865.8 CEG40981.1 - 1.6e-05 24.9 1.4 0.5 10.3 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 CEG40981.1 - 0.037 14.5 2.5 2.4 8.8 0.6 3.4 2 2 0 2 2 2 0 HEAT-like repeat DUF4490 PF14892.6 CEG40982.1 - 5.6e-05 23.1 0.2 0.014 15.5 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4490) Complex1_LYR PF05347.15 CEG40983.1 - 0.0003 20.8 0.4 0.00049 20.1 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.6 CEG40984.1 - 2.8e-24 85.1 4.6 4.9e-13 49.3 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG40984.1 - 1.3e-21 76.9 0.1 3.4e-16 59.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEG40984.1 - 1.4e-19 69.6 0.2 4.4e-07 30.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CEG40984.1 - 5.9e-18 64.7 4.3 1e-06 28.9 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG40984.1 - 6.2e-18 63.0 0.8 0.00022 21.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 CEG40984.1 - 2.2e-08 33.9 0.0 4.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEG40984.1 - 5.7e-08 32.5 0.1 1.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Glyco_hydro_43 PF04616.14 CEG40985.1 - 3.3e-35 121.8 1.9 4.4e-35 121.4 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nitroreductase PF00881.24 CEG40985.1 - 1.1e-25 90.6 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CEG40985.1 - 0.00042 19.9 0.0 1.5 8.4 0.0 3.0 2 2 1 3 3 3 2 Putative TM nitroreductase Ran_BP1 PF00638.18 CEG40986.1 - 1.2e-12 48.1 0.7 2.4e-12 47.2 0.7 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 CEG40986.1 - 6.9e-05 23.4 3.9 0.00052 20.6 3.9 2.6 1 1 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) DUF1972 PF09314.11 CEG40986.1 - 0.002 17.7 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1972) Rep_fac-A_C PF08646.10 CEG40987.1 - 2e-41 141.2 3.0 4.7e-41 140.0 3.0 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CEG40987.1 - 9.2e-31 105.7 0.4 2.2e-29 101.2 0.5 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 CEG40987.1 - 8.2e-24 83.6 0.0 3.9e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CEG40987.1 - 2.2e-14 53.2 1.4 1.9e-10 40.6 0.0 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF4539 PF15072.6 CEG40987.1 - 0.11 12.5 0.0 34 4.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) zinc-ribbons_6 PF07191.12 CEG40987.1 - 0.14 12.1 7.2 0.31 11.1 7.2 1.5 1 0 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 CEG40987.1 - 0.28 11.2 2.7 0.63 10.1 2.7 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 CEG40987.1 - 0.41 10.7 4.7 0.84 9.7 4.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 CEG40987.1 - 4.2 7.0 6.0 31 4.3 2.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PADR1 PF08063.12 CEG40987.1 - 8.8 6.2 7.8 24 4.8 7.8 1.7 1 0 0 1 1 1 0 PADR1 (NUC008) domain CART PF06373.11 CEG40989.1 - 0.046 13.9 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) DIM1 PF02966.16 CEG40990.1 - 2.1e-47 160.3 0.2 2.4e-47 160.0 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CEG40990.1 - 0.073 13.1 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TPR_2 PF07719.17 CEG40991.1 - 3.1e-29 98.7 27.2 0.0013 18.7 0.5 10.4 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 CEG40991.1 - 3.7e-22 77.2 21.2 2.9e-05 23.7 0.4 9.8 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEG40991.1 - 9.5e-20 69.1 11.1 0.027 14.7 0.1 10.1 10 1 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEG40991.1 - 2.3e-14 52.8 16.9 0.012 16.4 0.1 9.4 3 3 7 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG40991.1 - 9.4e-14 51.3 12.2 0.022 14.9 0.1 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEG40991.1 - 2.3e-13 49.6 15.1 0.14 11.9 0.1 8.7 7 2 2 9 9 9 4 TPR repeat TPR_15 PF13429.6 CEG40991.1 - 6.6e-11 41.9 5.2 0.036 13.3 1.3 5.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG40991.1 - 2.1e-09 37.7 10.9 0.031 14.8 0.0 6.7 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG40991.1 - 1.3e-07 31.1 12.6 0.28 11.3 0.1 7.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG40991.1 - 1.3e-06 28.3 12.4 3.9 8.1 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG40991.1 - 2.5e-06 28.0 15.3 0.064 13.9 0.2 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG40991.1 - 6.7e-06 26.3 21.7 0.13 12.6 0.6 6.3 5 3 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG40991.1 - 0.005 17.0 7.4 0.23 11.7 0.1 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CEG40991.1 - 0.028 14.1 1.9 18 5.0 0.0 4.0 3 1 0 4 4 4 0 26S proteasome subunit RPN7 DUF3856 PF12968.7 CEG40991.1 - 0.2 11.7 6.1 1.1 9.3 0.3 4.0 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 CEG40991.1 - 0.24 11.1 8.2 0.75 9.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CEG40991.1 - 0.74 9.8 13.3 6.5 6.8 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat fn3 PF00041.21 CEG40996.1 - 3e-51 171.7 29.7 2.1e-14 53.6 0.2 12.9 14 0 0 14 14 14 11 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG40996.1 - 1.3e-11 44.9 13.7 2e-05 25.0 0.3 8.2 9 0 0 9 9 9 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CEG40996.1 - 2e-08 34.5 1.4 0.094 13.1 0.0 7.3 8 0 0 8 8 8 1 Uncharacterised conserved protein (DUF2369) Acyltransferase PF01553.21 CEG40999.1 - 0.039 13.6 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Acyltransferase UCR_14kD PF02271.16 CEG41003.1 - 0.034 14.1 0.1 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit SAM_KSR1 PF13543.6 CEG41003.1 - 0.042 14.0 0.1 0.98 9.6 0.0 2.4 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 EF-hand_8 PF13833.6 CEG41004.1 - 2.5e-07 30.5 1.1 2.5e-07 30.5 1.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CEG41004.1 - 2.3e-06 28.0 5.5 1.4e-05 25.5 3.3 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG41004.1 - 6.5e-05 22.2 6.9 6.8e-05 22.1 1.4 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CEG41004.1 - 0.00015 21.4 1.5 0.12 12.3 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain SICA_C PF12879.7 CEG41004.1 - 0.17 11.9 0.3 0.57 10.2 0.3 1.9 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain Kazal_2 PF07648.15 CEG41005.1 - 2.1e-09 37.3 5.5 4.4e-09 36.3 5.5 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG41005.1 - 1.7e-07 31.1 5.3 2e-07 30.9 4.6 1.5 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Tis11B_N PF04553.12 CEG41005.1 - 0.033 14.8 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 Tis11B like protein, N terminus NAD_binding_10 PF13460.6 CEG41006.1 - 1.9e-18 67.0 0.0 2.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CEG41006.1 - 4.2e-12 45.6 0.1 4.1e-11 42.4 0.1 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CEG41006.1 - 9.5e-08 31.9 0.1 2.2e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CEG41006.1 - 2e-07 30.7 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEG41006.1 - 0.0072 15.5 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CEG41006.1 - 0.009 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF4112 PF13430.6 CEG41006.1 - 0.069 13.4 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DBD_Tnp_Mut PF03108.15 CEG41007.1 - 0.0042 17.1 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 MuDR family transposase Abhydrolase_6 PF12697.7 CEG41009.1 - 0.021 15.4 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF818 PF05677.12 CEG41009.1 - 0.029 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 CEG41009.1 - 0.058 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein Pga1 PF10333.9 CEG41011.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Glyco_hydro_12 PF01670.16 CEG41012.1 - 1.4e-09 38.3 0.1 1.8e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 SH3_19 PF18597.1 CEG41012.1 - 0.031 14.1 0.5 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain CDC45 PF02724.14 CEG41014.1 - 6.2 5.0 14.8 7.9 4.6 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Fe-ADH PF00465.19 CEG41015.1 - 0.063 12.1 0.0 0.063 12.1 0.0 1.0 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase EarP PF10093.9 CEG41015.1 - 0.066 12.3 0.0 0.066 12.3 0.0 1.0 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Calreticulin PF00262.18 CEG41016.1 - 1.2e-145 485.0 9.2 1.5e-145 484.7 9.2 1.1 1 0 0 1 1 1 1 Calreticulin family Flavi_NS2B PF01002.19 CEG41016.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B DUF1416 PF07210.12 CEG41016.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Proteasome PF00227.26 CEG41017.1 - 5.4e-31 107.6 0.0 6.2e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MatE PF01554.18 CEG41018.1 - 1.1e-45 155.1 32.4 3.1e-24 85.5 9.9 2.2 2 0 0 2 2 2 2 MatE zf-CCHC_3 PF13917.6 CEG41018.1 - 7e-21 73.9 1.1 1.3e-20 73.1 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEG41018.1 - 0.13 12.4 0.7 0.27 11.4 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle CBS PF00571.28 CEG41019.1 - 8.4e-07 29.4 0.6 0.011 16.2 0.9 3.7 3 0 0 3 3 3 3 CBS domain tRNA-synt_1b PF00579.25 CEG41020.1 - 1.7e-78 263.9 0.0 2.1e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CEG41020.1 - 7e-06 25.7 0.1 1.7e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 S4 domain Acetyltransf_6 PF13480.7 CEG41020.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Elicitin PF00964.17 CEG41024.1 - 2e-13 50.2 5.4 2.5e-13 49.9 5.4 1.1 1 0 0 1 1 1 1 Elicitin LRR_6 PF13516.6 CEG41025.1 - 2.7e-17 61.3 12.9 2.1e-05 24.2 0.4 5.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 CEG41025.1 - 0.00042 20.0 3.8 0.033 13.9 1.6 3.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CEG41025.1 - 0.00082 19.7 4.0 0.043 14.3 0.2 2.9 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG41025.1 - 0.0033 17.8 0.9 8.9 7.3 0.0 3.8 4 0 0 4 4 4 1 Leucine Rich Repeat Atx10homo_assoc PF09759.9 CEG41025.1 - 0.043 13.8 0.4 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain RNA_pol_3_Rpc31 PF11705.8 CEG41025.1 - 0.21 11.8 8.3 0.3 11.3 7.4 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 CEG41025.1 - 0.46 8.5 9.1 0.66 8.0 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi LisH_2 PF16045.5 CEG41026.1 - 9.6e-08 30.9 0.0 1.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 CEG41026.1 - 0.00055 20.1 0.0 0.0033 17.7 0.0 2.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Pox_A_type_inc PF04508.12 CEG41026.1 - 5 7.1 8.0 20 5.3 0.0 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2333 PF10095.9 CEG41028.1 - 7.4 5.5 14.2 0.18 10.8 2.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2333) C2 PF00168.30 CEG41029.1 - 5.1e-07 29.9 0.2 1.1e-05 25.6 0.2 2.4 1 1 0 1 1 1 1 C2 domain DOPA_dioxygen PF08883.11 CEG41029.1 - 0.13 12.4 0.4 0.45 10.7 0.2 2.0 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family GIT_CC PF16559.5 CEG41029.1 - 0.68 9.8 4.3 1.2 9.0 0.6 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 CEG41029.1 - 0.7 8.7 13.4 0.21 10.4 4.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AdenylateSensor PF16579.5 CEG41029.1 - 1.1 9.8 3.5 1 9.9 0.6 2.5 2 1 1 3 3 3 0 Adenylate sensor of SNF1-like protein kinase C2 PF00168.30 CEG41030.1 - 3.9e-08 33.5 0.0 9.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 CEG41031.1 - 9.7e-11 41.9 0.1 2e-09 37.7 0.1 2.6 1 1 0 1 1 1 1 C2 domain SCP2 PF02036.17 CEG41033.1 - 2.6e-06 27.8 0.0 3.4e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 SCP-2 sterol transfer family rve PF00665.26 CEG41034.1 - 1.5e-11 44.5 0.0 2.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 CEG41034.1 - 5.6e-05 22.9 0.1 7.7e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CEG41034.1 - 0.0028 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain JHY PF15261.6 CEG41037.1 - 1.1e-20 74.6 5.4 1.1e-20 74.6 5.4 2.2 2 0 0 2 2 2 1 Jhy protein DivIC PF04977.15 CEG41037.1 - 2.1 8.2 5.1 1.7 8.5 0.1 2.8 3 0 0 3 3 3 0 Septum formation initiator APG12 PF04110.13 CEG41038.1 - 7e-30 103.3 0.0 8.4e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CEG41038.1 - 3.2e-06 27.3 0.0 3.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Choline_transpo PF04515.12 CEG41039.1 - 3.8e-72 243.2 20.2 3.8e-72 243.2 20.2 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter Metallophos PF00149.28 CEG41040.1 - 5.2e-08 33.6 0.8 2.5e-07 31.4 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EPL1 PF10513.9 CEG41043.1 - 1.7e-06 28.5 2.3 2e-06 28.3 0.2 2.2 2 2 0 2 2 2 1 Enhancer of polycomb-like Cnd1_N PF12922.7 CEG41043.1 - 0.14 12.0 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF676 PF05057.14 CEG41044.1 - 0.046 13.2 1.2 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PhoD_N PF16655.5 CEG41044.1 - 0.31 11.6 1.2 0.76 10.4 0.3 2.2 2 1 1 3 3 3 0 PhoD-like phosphatase, N-terminal domain CEP76-C2 PF15627.6 CEG41045.1 - 1.9e-40 138.0 0.2 4.2e-40 136.9 0.2 1.6 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 CEG41045.1 - 0.014 15.9 0.0 0.064 13.7 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ion_trans PF00520.31 CEG41046.1 - 4.8e-16 58.7 6.2 6.7e-16 58.3 6.2 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CEG41046.1 - 2.5e-11 43.5 0.0 8.2e-11 41.8 0.0 2.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 CEG41047.1 - 1.4e-19 70.0 0.0 4.5e-11 42.7 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cyclase_polyket PF04673.12 CEG41047.1 - 0.0009 19.5 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Polyketide synthesis cyclase DUF3086 PF11285.8 CEG41047.1 - 0.027 13.6 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Ammonium_transp PF00909.21 CEG41047.1 - 0.1 11.3 5.4 0.93 8.1 0.6 2.3 2 0 0 2 2 2 0 Ammonium Transporter Family WD40 PF00400.32 CEG41048.1 - 1.4e-26 92.2 11.0 0.0045 17.8 0.0 10.0 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41048.1 - 1.5e-11 44.4 4.9 0.016 15.5 0.0 7.3 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain GvpO PF05800.11 CEG41051.1 - 0.072 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO ZnuA PF01297.17 CEG41051.1 - 0.17 11.3 0.6 0.31 10.4 0.3 1.6 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic MBOAT PF03062.19 CEG41053.1 - 5.7e-37 127.9 13.3 8.4e-37 127.3 13.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Maf PF02545.14 CEG41054.1 - 2.4e-43 147.8 0.0 2.8e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein UPF0004 PF00919.20 CEG41054.1 - 0.0068 16.4 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 ANTAR PF03861.14 CEG41054.1 - 0.18 11.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 ANTAR domain AAA_6 PF12774.7 CEG41055.1 - 6.2e-147 488.8 1.0 1.5e-144 480.9 0.0 3.7 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG41055.1 - 2.8e-128 428.4 9.6 2.8e-128 428.4 9.6 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG41055.1 - 9e-104 346.4 0.0 3.9e-103 344.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG41055.1 - 3.3e-98 328.7 0.7 1e-94 317.2 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG41055.1 - 1.6e-88 295.5 2.1 1.6e-88 295.5 2.1 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG41055.1 - 1.4e-63 213.7 3.2 3.2e-59 199.5 0.1 5.2 4 1 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG41055.1 - 5.7e-56 188.8 0.1 1.4e-55 187.6 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG41055.1 - 2.1e-50 171.7 16.0 4.3e-50 170.7 16.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG41055.1 - 7.8e-43 145.4 1.7 1.8e-40 137.8 0.0 3.8 5 0 0 5 5 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG41055.1 - 1.2e-30 106.3 1.0 2.7e-29 101.9 0.1 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG41055.1 - 2e-19 69.6 0.9 2.1e-18 66.3 0.1 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 CEG41055.1 - 3.8e-11 43.1 0.6 0.047 13.7 0.0 6.0 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG41055.1 - 9.9e-09 35.8 0.0 0.0075 16.7 0.0 5.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 CEG41055.1 - 1.2e-08 35.3 10.7 0.0061 16.8 0.0 6.4 8 0 0 8 8 6 2 AAA domain AAA PF00004.29 CEG41055.1 - 2.9e-08 34.2 0.1 0.21 12.0 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEG41055.1 - 7.1e-05 23.2 1.0 4.3 7.8 0.0 4.9 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.6 CEG41055.1 - 0.00015 22.3 7.5 0.1 13.1 0.0 5.5 7 0 0 7 7 4 1 AAA domain ABC_tran PF00005.27 CEG41055.1 - 0.00036 21.0 1.9 1.6 9.3 0.0 4.4 4 0 0 4 4 3 1 ABC transporter AAA_30 PF13604.6 CEG41055.1 - 0.01 15.6 7.0 0.54 10.0 0.1 4.1 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 CEG41055.1 - 0.018 15.0 0.1 4.5 7.2 0.1 3.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CEG41055.1 - 0.032 14.3 0.9 1.4 8.9 0.0 3.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 CEG41055.1 - 0.12 12.6 2.5 22 5.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CEG41055.1 - 0.14 12.1 2.1 8.6 6.4 0.1 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CEG41055.1 - 0.17 12.1 0.2 1.1e+02 3.0 0.1 3.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CEG41055.1 - 0.21 11.4 1.5 44 3.9 0.1 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 CEG41055.1 - 1.2 8.1 9.6 0.37 9.8 0.2 3.9 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_19 PF13245.6 CEG41055.1 - 1.9 8.8 4.2 3.5 7.9 0.1 3.6 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 CEG41055.1 - 1.9 8.6 6.9 6.9 6.8 0.0 4.5 5 0 0 5 5 3 0 Sigma-54 interaction domain PX PF00787.24 CEG41056.1 - 2.2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PX domain CENP-H PF05837.12 CEG41056.1 - 0.0056 17.1 9.3 0.0095 16.3 9.3 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF724 PF05266.14 CEG41056.1 - 0.034 14.0 4.6 0.065 13.1 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 CEG41056.1 - 1.2 9.4 4.6 2.7 8.2 4.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2381 PF09544.10 CEG41056.1 - 2.2 7.8 9.7 2.1 7.8 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) RXLR PF16810.5 CEG41057.1 - 0.35 11.3 5.2 0.073 13.5 0.8 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity N2227 PF07942.12 CEG41060.1 - 1.2e-74 250.9 0.0 6.5e-38 130.5 0.0 2.4 1 1 1 2 2 2 2 N2227-like protein JAB PF01398.21 CEG41060.1 - 6.4e-33 113.2 0.2 1.8e-32 111.8 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CEG41060.1 - 2.8e-13 50.3 0.8 6e-13 49.2 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CEG41060.1 - 2.1e-05 24.3 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Methyltransf_23 PF13489.6 CEG41060.1 - 0.00059 19.7 0.0 0.0023 17.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CEG41060.1 - 0.00093 18.5 0.0 0.0024 17.1 0.0 1.6 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 CEG41060.1 - 0.0014 19.3 0.0 0.008 16.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG41060.1 - 0.0056 17.3 0.0 0.028 15.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 CEG41060.1 - 0.037 12.6 0.1 0.071 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 CEG41060.1 - 0.067 13.9 0.0 0.65 10.7 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 CEG41061.1 - 1.5e-21 75.8 0.2 1.7e-21 75.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ribosomal_L37 PF08561.10 CEG41062.1 - 1.2e-07 32.2 0.8 1.2e-06 29.0 0.7 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 TPR_7 PF13176.6 CEG41063.1 - 0.0022 17.9 0.2 3.9 7.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG41063.1 - 0.067 13.3 0.6 7.5 6.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG41063.1 - 0.26 11.2 2.6 4.1 7.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat GldM_N PF12081.8 CEG41065.1 - 0.051 13.7 0.3 0.051 13.7 0.3 1.1 1 0 0 1 1 1 0 GldM N-terminal domain Tfb5 PF06331.12 CEG41068.1 - 4e-28 97.2 0.0 4.4e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Mtc PF03820.17 CEG41069.1 - 1.2e-16 60.6 0.0 1.3e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SPX PF03105.19 CEG41070.1 - 7e-13 49.2 13.1 1.7e-11 44.7 0.1 3.0 2 1 1 3 3 3 2 SPX domain TssC PF17541.2 CEG41070.1 - 0.00032 19.6 0.4 0.00048 19.1 0.4 1.2 1 0 0 1 1 1 1 Type VI secretion system, TssC, VipB DUF2383 PF09537.10 CEG41070.1 - 0.0078 16.6 0.3 0.018 15.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF2001 PF09393.10 CEG41070.1 - 0.066 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein DUF4559 PF15112.6 CEG41070.1 - 1.6 8.3 6.4 6.1 6.4 3.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Motile_Sperm PF00635.26 CEG41071.1 - 2e-16 59.8 0.0 9.6e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF5575 PF17738.1 CEG41072.1 - 0.19 10.8 4.3 1.6 7.7 4.3 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5575) RRM_1 PF00076.22 CEG41073.1 - 6.6e-37 125.2 0.0 1.6e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG41073.1 - 1.4e-06 28.3 0.0 0.037 14.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CEG41073.1 - 0.009 16.0 0.0 0.055 13.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1604 PF07713.13 CEG41074.1 - 3.6e-33 113.2 1.6 3.6e-33 113.2 1.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 CEG41074.1 - 9.4e-08 31.8 0.6 2e-07 30.8 0.6 1.5 1 0 0 1 1 1 1 G-patch domain PX PF00787.24 CEG41074.1 - 9.2e-05 22.4 0.1 0.00039 20.4 0.0 2.1 1 1 0 1 1 1 1 PX domain G-patch_2 PF12656.7 CEG41074.1 - 0.0045 17.1 0.1 0.0045 17.1 0.1 2.8 3 0 0 3 3 3 1 G-patch domain zf-RING_2 PF13639.6 CEG41074.1 - 0.44 10.9 7.8 2.4 8.5 1.3 3.4 3 0 0 3 3 3 0 Ring finger domain zf-RING_11 PF17123.5 CEG41074.1 - 4.3 7.2 12.9 1.4 8.7 0.8 3.5 3 0 0 3 3 3 0 RING-like zinc finger Thioredoxin PF00085.20 CEG41075.1 - 9.6e-14 51.2 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEG41075.1 - 0.0079 16.3 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEG41075.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 CEG41075.1 - 0.057 13.8 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CEG41075.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain Ribosomal_L3 PF00297.22 CEG41079.1 - 9.2e-15 54.5 0.6 1.5e-14 53.8 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L3 PXA PF02194.15 CEG41080.1 - 9e-22 77.9 0.0 2.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 CEG41080.1 - 7.6e-13 49.0 0.0 8.4e-12 45.7 0.0 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CEG41080.1 - 5.1e-06 26.4 0.4 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 PX domain FYVE_2 PF02318.16 CEG41080.1 - 8.6e-05 22.7 3.2 0.00027 21.1 3.2 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 CEG41080.1 - 0.0034 17.5 4.4 0.0034 17.5 4.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 CEG41080.1 - 6 6.8 8.0 3.7 7.5 3.0 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2462 PF09495.10 CEG41081.1 - 0.0027 18.4 7.7 0.0027 18.4 7.7 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) DUF779 PF05610.11 CEG41083.1 - 0.028 14.7 0.2 0.053 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF779) C1-set PF07654.15 CEG41083.1 - 0.029 14.7 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Glyco_hydro_3 PF00933.21 CEG41088.1 - 4.6e-57 193.8 0.0 6e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEG41088.1 - 3.4e-15 56.6 0.0 5.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Oxidored_FMN PF00724.20 CEG41090.1 - 3.3e-78 263.3 0.0 3.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family rOmpB PF12334.8 CEG41090.1 - 0.11 11.9 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Rickettsia outer membrane protein B Exo_endo_phos PF03372.23 CEG41091.1 - 5.2e-06 26.1 0.0 2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vps54 PF07928.12 CEG41093.1 - 1.4e-45 155.0 1.3 1.4e-45 155.0 1.3 2.9 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 CEG41093.1 - 1.9e-08 33.9 2.6 1.9e-08 33.9 2.6 2.8 4 0 0 4 4 4 1 Vacuolar-sorting protein 54, of GARP complex Erythro_esteras PF05139.14 CEG41093.1 - 0.046 13.5 0.4 0.087 12.6 0.4 1.4 1 0 0 1 1 1 0 Erythromycin esterase KMP11 PF03037.16 CEG41093.1 - 0.063 14.1 0.6 17 6.3 0.1 2.8 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 CHAD PF05235.14 CEG41093.1 - 0.076 13.0 3.8 0.15 12.0 3.4 1.7 1 1 0 1 1 1 0 CHAD domain ARL2_Bind_BART PF11527.8 CEG41093.1 - 1.8 8.7 5.3 0.79 9.8 0.1 3.1 4 0 0 4 4 4 0 The ARF-like 2 binding protein BART Sec8_exocyst PF04048.14 CEG41093.1 - 2.7 7.9 10.0 0.51 10.2 1.7 2.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain LSM PF01423.22 CEG41094.1 - 1.1e-17 63.4 0.2 1.4e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEG41094.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein CTP_transf_1 PF01148.20 CEG41098.1 - 2.3e-64 217.7 19.9 3.4e-64 217.2 19.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family RRM_1 PF00076.22 CEG41098.1 - 5.7e-14 51.7 0.0 1.8e-05 24.5 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG41098.1 - 0.039 13.8 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif BRCT PF00533.26 CEG41099.1 - 3.1e-08 33.9 0.0 3.2e-05 24.2 0.0 4.0 4 1 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 CEG41099.1 - 2.1e-07 30.7 17.3 4.2e-07 29.7 17.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41099.1 - 3.5e-07 30.4 17.1 7.8e-07 29.3 17.1 1.6 1 0 0 1 1 1 1 Ring finger domain PTCB-BRCT PF12738.7 CEG41099.1 - 3.7e-07 30.0 0.0 1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain zf-C3HC4_3 PF13920.6 CEG41099.1 - 1e-06 28.5 15.0 2.1e-06 27.5 15.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 CEG41099.1 - 5.5e-06 26.7 1.8 0.005 17.2 0.0 4.3 4 1 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_5 PF14634.6 CEG41099.1 - 5.8e-05 23.0 16.0 0.00012 22.0 16.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG41099.1 - 6.1e-05 23.0 12.2 6.1e-05 23.0 12.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG41099.1 - 0.00071 19.4 18.6 0.0015 18.3 18.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RTT107_BRCT_5 PF16770.5 CEG41099.1 - 0.0019 18.1 0.0 5.5 6.9 0.0 3.7 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain zf-rbx1 PF12678.7 CEG41099.1 - 0.014 15.7 10.8 0.042 14.1 10.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CEG41099.1 - 0.086 12.7 5.9 0.21 11.5 5.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CEG41099.1 - 0.21 11.5 15.2 0.54 10.2 15.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CEG41099.1 - 0.66 10.2 10.6 1.8 8.7 10.6 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CEG41099.1 - 0.92 9.3 13.5 2.5 8.0 13.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CEG41099.1 - 6 7.1 18.7 14 6.0 18.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 CEG41099.1 - 7.1 6.4 12.6 16 5.2 12.6 1.6 1 0 0 1 1 1 0 P-11 zinc finger Chromo PF00385.24 CEG41100.1 - 2.9e-20 71.9 8.1 4.2e-10 39.4 1.3 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain GREB1 PF15782.5 CEG41100.1 - 4 4.4 12.3 5.3 4.0 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 CEG41100.1 - 7.3 7.1 8.6 11 6.5 8.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Membralin PF09746.9 CEG41100.1 - 7.7 5.4 6.3 11 5.0 6.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.6 CEG41100.1 - 9.3 5.5 8.4 13 5.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps8 PF12816.7 CEG41101.1 - 3.4e-53 180.1 0.1 5.2e-51 173.0 0.0 3.2 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CEG41101.1 - 9.6e-12 45.0 7.5 6.6e-05 22.8 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS WD40 PF00400.32 CEG41101.1 - 0.0026 18.5 0.2 0.014 16.3 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41101.1 - 0.025 14.9 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain P_C10 PF14974.6 CEG41103.1 - 0.072 13.2 0.0 0.078 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein C10 Ntox16 PF15523.6 CEG41105.1 - 0.013 15.7 0.8 0.016 15.5 0.8 1.2 1 0 0 1 1 1 0 Novel toxin 16 RVP_2 PF08284.11 CEG41106.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Cyclin_N PF00134.23 CEG41110.1 - 1.4e-39 134.7 2.7 2.5e-39 133.9 1.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEG41110.1 - 1.1e-15 57.7 2.6 1.2e-15 57.7 0.0 2.4 3 0 0 3 3 3 1 Cyclin, C-terminal domain DUF755 PF05501.11 CEG41110.1 - 0.64 10.3 7.2 1.3 9.3 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GKAP PF03359.13 CEG41110.1 - 1.6 8.2 7.5 0.21 11.1 2.8 2.1 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein TFIIB PF00382.19 CEG41115.1 - 5.3e-28 96.9 0.1 1.4e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CEG41115.1 - 2.4e-15 56.7 1.8 2.4e-15 56.7 1.8 3.1 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CEG41115.1 - 3.8e-07 29.5 5.9 3.8e-07 29.5 5.9 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 CEG41115.1 - 0.026 14.5 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain GRIM-19 PF06212.12 CEG41116.1 - 2.5e-33 114.8 0.1 2.9e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein Rpn3_C PF08375.11 CEG41117.1 - 7.1e-28 96.8 2.6 1.4e-27 95.9 2.6 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CEG41117.1 - 1.5e-22 80.1 0.6 6.2e-21 74.9 0.0 3.0 3 0 0 3 3 3 1 PCI domain BTB_3 PF16017.5 CEG41121.1 - 0.047 13.8 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Loricrin PF15847.5 CEG41123.1 - 0.0086 15.2 0.7 0.0086 15.2 0.7 1.0 1 0 0 1 1 1 1 Major keratinocyte cell envelope protein Adaptin_N PF01602.20 CEG41124.1 - 3.5e-100 336.0 5.7 1.2e-99 334.2 5.7 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEG41124.1 - 1.8e-43 148.4 3.4 2.3e-42 144.8 0.1 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CEG41124.1 - 2.7e-18 66.1 0.0 6.8e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CEG41124.1 - 2.3e-10 40.7 1.1 0.38 11.2 0.0 5.8 3 2 0 4 4 4 2 HEAT repeats Arm_2 PF04826.13 CEG41124.1 - 6.9e-05 22.4 1.2 0.00066 19.2 0.4 2.6 1 1 1 2 2 2 1 Armadillo-like HEAT PF02985.22 CEG41124.1 - 0.00078 19.5 6.9 5 7.6 0.0 5.5 6 0 0 6 6 5 1 HEAT repeat SPO22 PF08631.10 CEG41124.1 - 0.026 14.0 1.4 1.2 8.6 0.1 3.2 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Na_Ca_ex_C PF16494.5 CEG41124.1 - 0.039 14.4 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Arginase PF00491.21 CEG41124.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Arginase family mRNA_stabil PF13929.6 CEG41124.1 - 0.1 11.6 0.1 0.29 10.1 0.1 1.7 1 0 0 1 1 1 0 mRNA stabilisation Arm PF00514.23 CEG41124.1 - 0.13 12.3 0.1 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SirA PF10747.9 CEG41124.1 - 0.16 12.3 0.7 0.54 10.6 0.7 1.9 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA V-ATPase_H_C PF11698.8 CEG41124.1 - 4.6 7.4 4.9 13 5.9 0.0 3.7 3 1 1 4 4 4 0 V-ATPase subunit H dUTPase PF00692.19 CEG41125.1 - 1.3e-45 154.3 0.0 1.8e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase Methyltr_RsmB-F PF01189.17 CEG41126.1 - 3.8e-33 114.8 0.1 3.8e-31 108.3 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F zf-CCHC_2 PF13696.6 CEG41126.1 - 1.7e-05 24.6 1.9 1.7e-05 24.5 0.6 1.7 2 0 0 2 2 2 1 Zinc knuckle FtsJ PF01728.19 CEG41126.1 - 0.00046 20.3 0.1 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase zf-CCHC PF00098.23 CEG41126.1 - 0.29 11.3 3.2 0.3 11.3 1.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Cu-oxidase_2 PF07731.14 CEG41127.1 - 4.4e-34 117.2 10.0 3.5e-28 98.0 1.3 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CEG41127.1 - 1.4e-30 106.5 0.0 3.6e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEG41127.1 - 7.6e-30 103.4 3.8 8.6e-29 100.0 0.1 3.2 4 0 0 4 4 4 1 Multicopper oxidase PAP2 PF01569.21 CEG41127.1 - 0.00041 20.1 4.1 0.0012 18.6 4.1 1.7 1 0 0 1 1 1 1 PAP2 superfamily FGGY_N PF00370.21 CEG41128.1 - 5e-20 72.1 0.3 1.8e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEG41128.1 - 0.0061 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HTH_23 PF13384.6 CEG41128.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEG41128.1 - 0.025 14.9 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.6 CEG41128.1 - 0.049 13.8 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Trypsin_2 PF13365.6 CEG41129.1 - 1.3e-16 61.8 0.3 4e-16 60.3 0.3 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG41129.1 - 0.00051 19.9 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.9 CEG41129.1 - 0.011 14.4 0.0 0.45 9.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 DASH_Dam1 PF08653.10 CEG41130.1 - 6.5e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 Rio2_N PF09202.11 CEG41130.1 - 0.027 14.7 0.2 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Rio2, N-terminal TrmB PF01978.19 CEG41130.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MPP6 PF10175.9 CEG41131.1 - 2.4e-15 57.2 3.1 2.4e-15 57.2 3.1 1.7 2 0 0 2 2 2 1 M-phase phosphoprotein 6 Efg1 PF10153.9 CEG41131.1 - 0.81 10.1 8.1 0.072 13.5 1.0 2.1 2 0 0 2 2 2 0 rRNA-processing protein Efg1 FIBP PF05427.11 CEG41132.1 - 0.04 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) T3SS_needle_E PF08988.10 CEG41132.1 - 0.13 12.4 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle INTAP PF16617.5 CEG41132.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region MORN PF02493.20 CEG41133.1 - 7e-52 170.3 97.4 1.3e-05 24.8 0.0 17.5 18 0 0 18 18 18 15 MORN repeat PRKCSH-like PF12999.7 CEG41134.1 - 2.8e-21 76.1 12.5 8.9e-21 74.5 12.5 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CEG41134.1 - 7.8e-14 51.6 0.5 1.6e-13 50.6 0.5 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 CEG41134.1 - 0.095 12.9 17.0 1.4 9.2 5.5 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4298 PF14131.6 CEG41134.1 - 0.13 12.2 1.2 0.39 10.7 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Exonuc_VII_L PF02601.15 CEG41134.1 - 0.18 11.3 1.3 0.28 10.7 1.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 CEG41137.1 - 0.43 10.9 4.9 2.7 8.3 0.2 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-CCHC PF00098.23 CEG41139.1 - 0.00047 20.1 2.9 0.00047 20.1 2.9 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEG41139.1 - 0.0014 18.3 1.0 0.0033 17.1 1.0 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CEG41139.1 - 0.11 12.3 1.2 0.2 11.4 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4413 PF14372.6 CEG41140.1 - 0.0041 17.5 0.0 0.005 17.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) zf-C3HC4_2 PF13923.6 CEG41141.1 - 2.1e-12 46.7 9.4 4e-12 45.8 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG41141.1 - 3.6e-09 36.3 9.6 7.6e-09 35.3 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41141.1 - 1.4e-07 31.8 9.1 2.9e-07 30.7 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG41141.1 - 1.8e-06 27.7 8.9 3.8e-06 26.6 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41141.1 - 7.5e-06 25.9 8.0 1.9e-05 24.6 8.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG41141.1 - 2.5e-05 24.1 8.4 8.7e-05 22.4 8.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEG41141.1 - 0.0016 18.6 8.7 0.0033 17.5 8.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CEG41141.1 - 0.0018 18.0 4.6 0.0041 16.9 4.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CEG41141.1 - 0.0054 17.0 9.3 0.0092 16.3 7.7 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEG41141.1 - 0.0071 16.4 2.7 0.014 15.4 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEG41141.1 - 0.0093 15.7 8.3 0.04 13.7 8.6 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CEG41141.1 - 0.013 15.4 5.1 0.023 14.5 5.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RAWUL PF16207.5 CEG41141.1 - 0.04 14.6 0.1 0.086 13.5 0.1 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Prok-RING_4 PF14447.6 CEG41141.1 - 0.49 10.3 11.3 35 4.3 12.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CEG41141.1 - 0.83 9.5 7.1 2.3 8.1 7.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 CEG41141.1 - 1.4 8.8 7.9 2.9 7.7 7.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING-like PF08746.11 CEG41141.1 - 2.6 8.4 6.2 6.1 7.2 6.2 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_5 PF17121.5 CEG41141.1 - 3.4 7.6 11.5 3.9 7.4 7.7 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PPTA PF01239.22 CEG41142.1 - 1.9e-17 62.4 18.7 5.9e-06 25.8 0.4 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DpnII PF04556.12 CEG41142.1 - 0.1 11.9 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 DpnII restriction endonuclease Glyco_hydro_85 PF03644.13 CEG41147.1 - 6.2e-74 249.1 0.3 1e-73 248.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 FYVE PF01363.21 CEG41150.1 - 0.12 12.5 11.3 0.086 13.0 9.2 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-B_box PF00643.24 CEG41150.1 - 0.35 11.1 5.7 1.1 9.5 5.1 2.2 1 1 0 1 1 1 0 B-box zinc finger FYVE_2 PF02318.16 CEG41150.1 - 0.67 10.2 7.6 1.3 9.3 7.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Pox_I1 PF03289.13 CEG41152.1 - 0.084 12.0 0.0 0.094 11.8 0.0 1.0 1 0 0 1 1 1 0 Poxvirus protein I1 zf-CCHC PF00098.23 CEG41153.1 - 7.3e-14 51.1 36.4 0.0011 19.0 0.4 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CEG41153.1 - 0.00055 19.6 30.4 0.017 14.9 0.4 5.4 5 0 0 5 5 5 4 Zinc knuckle RRM_1 PF00076.22 CEG41155.1 - 7e-16 57.8 0.1 1.6e-10 40.7 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.18 CEG41155.1 - 0.05 12.6 16.8 0.086 11.9 16.8 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RRM_occluded PF16842.5 CEG41155.1 - 0.13 12.1 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif UDPGP PF01704.18 CEG41156.1 - 6.4e-103 344.6 0.0 5.9e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase OHCU_decarbox PF09349.10 CEG41156.1 - 4.6e-35 121.4 1.4 4.6e-35 121.4 1.4 1.9 2 0 0 2 2 2 1 OHCU decarboxylase NTP_transf_3 PF12804.7 CEG41156.1 - 1.8e-06 28.4 0.4 0.1 13.0 0.1 2.9 2 0 0 2 2 2 2 MobA-like NTP transferase domain Acetyltransf_19 PF18015.1 CEG41156.1 - 0.051 13.8 0.1 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RRM_4 PF10598.9 CEG41156.1 - 0.087 13.2 0.0 21 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 DUF2110 PF09883.9 CEG41156.1 - 0.16 11.6 0.0 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) VMA21 PF09446.10 CEG41158.1 - 4.3e-16 58.8 6.8 5.3e-16 58.5 6.8 1.1 1 0 0 1 1 1 1 VMA21-like domain NHS PF15273.6 CEG41158.1 - 0.17 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 NHS-like LigB PF02900.18 CEG41159.1 - 6.4e-33 114.0 0.0 7.5e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase AvrRpt-cleavage PF05627.11 CEG41159.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr AAA_6 PF12774.7 CEG41161.1 - 2e-141 470.7 0.0 5.9e-140 465.9 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG41161.1 - 2.8e-131 438.3 8.1 2.8e-131 438.3 8.1 2.6 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG41161.1 - 3.7e-104 348.2 0.4 2.2e-103 345.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CEG41161.1 - 1.9e-97 325.7 0.0 6e-97 324.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CEG41161.1 - 1.1e-81 273.2 0.3 1e-80 270.0 0.0 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG41161.1 - 1.2e-80 269.4 0.0 6e-77 257.3 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG41161.1 - 7.2e-53 178.8 0.2 2e-52 177.3 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG41161.1 - 2.3e-45 155.2 10.0 4e-45 154.3 10.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG41161.1 - 3.8e-45 152.8 0.0 1.2e-41 141.6 0.0 3.4 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG41161.1 - 2.8e-31 108.3 0.0 1.1e-30 106.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG41161.1 - 2.1e-22 79.2 1.8 4.5e-22 78.1 0.0 2.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 CEG41161.1 - 1.4e-19 70.5 0.0 5.5e-07 29.7 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.6 CEG41161.1 - 2.7e-10 40.8 0.1 2.8e-09 37.6 0.1 2.9 1 1 0 1 1 1 1 von Willebrand factor type A domain AAA_22 PF13401.6 CEG41161.1 - 8.2e-05 22.9 2.5 3.3 8.0 0.0 5.4 5 0 0 5 5 4 1 AAA domain VWA PF00092.28 CEG41161.1 - 0.0007 19.9 0.0 0.0044 17.3 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF853 PF05872.12 CEG41161.1 - 0.0016 17.2 2.0 0.72 8.4 0.1 3.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.6 CEG41161.1 - 0.0068 16.1 1.6 7.9 6.1 0.2 3.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEG41161.1 - 0.0081 16.7 0.0 0.17 12.4 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG41161.1 - 0.011 16.2 0.2 1.2 9.6 0.1 3.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEG41161.1 - 0.022 13.8 0.1 1.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CEG41161.1 - 0.035 14.5 0.1 5.6 7.4 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_19 PF13245.6 CEG41161.1 - 0.041 14.2 1.1 4.2 7.7 0.1 3.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG41161.1 - 0.3 11.2 1.8 14 5.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain Spc7 PF08317.11 CEG41161.1 - 0.4 9.5 24.2 0.034 13.0 1.7 3.5 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 CEG41161.1 - 3.4 7.3 6.6 8.3 6.1 1.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_16 PF13191.6 CEG41161.1 - 5 7.5 12.0 8.7 6.7 0.0 5.9 6 0 0 6 6 6 0 AAA ATPase domain zf-RING_UBOX PF13445.6 CEG41162.1 - 1.1e-08 35.0 1.1 1.1e-08 35.0 1.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CEG41162.1 - 1.1e-07 31.9 3.2 4.4e-07 30.0 0.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 CEG41162.1 - 1.6e-07 31.4 0.0 6.1e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 CEG41162.1 - 1.9e-07 30.8 0.4 1.9e-07 30.8 0.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG41162.1 - 3.5e-06 26.8 2.8 1.3e-05 24.9 1.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41162.1 - 0.00015 22.0 9.0 0.0016 18.7 7.1 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG41162.1 - 0.0016 18.2 7.0 0.045 13.6 0.6 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG41162.1 - 0.0039 16.9 2.3 0.026 14.3 1.1 2.8 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CEG41162.1 - 0.019 14.9 2.0 0.019 14.9 2.0 2.3 2 1 0 2 2 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 CEG41162.1 - 0.063 13.2 0.8 0.16 11.9 0.6 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 CEG41162.1 - 0.098 12.5 0.5 0.37 10.7 0.5 2.0 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CEG41162.1 - 0.13 12.4 1.7 16 5.7 0.3 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CEG41162.1 - 0.15 11.9 9.2 5.2 7.0 0.4 3.5 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG41162.1 - 9.5 6.6 9.9 3.7 7.9 1.8 2.8 2 2 1 3 3 3 0 RING-H2 zinc finger domain DUF1577 PF07614.11 CEG41163.1 - 0.056 12.5 0.1 0.07 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Peptidase_C1 PF00112.23 CEG41164.1 - 1e-75 254.6 3.8 1.4e-75 254.2 3.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 CEG41164.1 - 1.3e-13 51.5 0.0 2.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 ML domain Inhibitor_I29 PF08246.12 CEG41164.1 - 2.9e-08 34.0 1.2 6.1e-08 33.0 1.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CEG41164.1 - 6.4e-05 21.9 2.0 0.0077 15.0 0.1 2.5 2 1 0 2 2 2 2 Peptidase C1-like family EFF-AFF PF14884.6 CEG41164.1 - 0.052 11.7 0.0 0.089 10.9 0.0 1.3 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Agglutinin_C PF18021.1 CEG41164.1 - 0.1 13.2 0.1 0.72 10.4 0.1 2.3 2 0 0 2 2 2 0 Agglutinin C-terminal Ank_2 PF12796.7 CEG41165.1 - 0.031 14.8 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Chromo PF00385.24 CEG41166.1 - 1.4e-12 47.4 6.1 4.5e-11 42.5 3.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Thioredoxin_12 PF18400.1 CEG41166.1 - 0.056 13.3 0.5 0.76 9.6 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain Actin PF00022.19 CEG41167.1 - 9.5e-50 169.4 0.0 1.1e-30 106.5 0.0 4.0 2 1 1 3 3 3 3 Actin MreB_Mbl PF06723.13 CEG41167.1 - 4.2e-05 22.5 0.0 0.0021 16.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Adap_comp_sub PF00928.21 CEG41168.1 - 2.4e-73 246.8 0.5 1.2e-39 136.3 0.1 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEG41168.1 - 1.6e-05 24.9 0.9 3e-05 24.0 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 CEG41168.1 - 3.8e-05 23.6 0.3 9.8e-05 22.3 0.2 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain SH3_5 PF08460.10 CEG41168.1 - 0.32 11.1 1.9 7.6 6.7 0.2 3.1 3 0 0 3 3 3 0 Bacterial SH3 domain SNF2_N PF00176.23 CEG41169.1 - 1.1e-61 208.5 0.0 2.2e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG41169.1 - 2.8e-11 43.7 0.0 9.1e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CEG41169.1 - 1e-05 25.3 14.1 3.1e-05 23.8 14.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 CEG41169.1 - 0.0012 18.1 3.2 0.029 13.6 0.0 2.4 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase F-box-like PF12937.7 CEG41169.1 - 0.008 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CEG41169.1 - 0.0098 15.8 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 F-box ResIII PF04851.15 CEG41169.1 - 0.036 14.1 0.0 0.26 11.3 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 CEG41169.1 - 0.23 11.4 17.0 0.031 14.1 12.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CEG41169.1 - 1.9 8.5 14.0 5.5 7.0 14.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG41169.1 - 2 8.4 15.6 4.5 7.2 15.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41169.1 - 5.7 7.1 13.5 13 5.9 13.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEG41169.1 - 6.9 6.6 15.5 18 5.3 15.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Asp_Arg_Hydrox PF05118.15 CEG41170.1 - 4.7e-44 150.0 0.0 7.2e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 CEG41170.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Tmemb_18A PF09771.9 CEG41170.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 SRX PF09201.10 CEG41171.1 - 0.034 14.0 0.4 0.068 13.0 0.4 1.5 1 1 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit TypeIII_RM_meth PF12564.8 CEG41171.1 - 0.091 12.9 0.2 0.29 11.3 0.2 2.0 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit CLASP_N PF12348.8 CEG41173.1 - 8.5e-07 28.8 0.0 1e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal Arm PF00514.23 CEG41173.1 - 0.12 12.5 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat TraE PF05309.11 CEG41173.1 - 0.28 10.5 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 TraE protein Pkinase PF00069.25 CEG41176.1 - 0.00051 19.5 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEG41176.1 - 0.015 14.7 0.9 0.052 12.9 0.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEG41176.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Cytochrom_B559 PF00283.19 CEG41177.1 - 0.017 14.6 0.3 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits DicB PF05358.11 CEG41180.1 - 0.046 13.9 0.4 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 DicB protein DUF4029 PF13221.6 CEG41180.1 - 0.094 13.4 0.1 0.27 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) LIM PF00412.22 CEG41181.1 - 1.6e-25 89.1 61.8 1.3e-09 38.1 8.6 5.2 6 0 0 6 6 6 4 LIM domain SH3_9 PF14604.6 CEG41181.1 - 2.4e-22 78.5 1.3 1.7e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CEG41181.1 - 6e-22 77.0 1.8 3.1e-10 39.5 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CEG41181.1 - 1.1e-18 66.6 0.3 2.4e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CEG41181.1 - 1.3e-08 35.0 3.6 0.00025 21.2 0.3 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain DZR PF12773.7 CEG41181.1 - 0.0012 18.8 1.1 0.0012 18.8 1.1 7.9 4 2 1 5 5 5 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEG41181.1 - 0.011 15.4 1.8 0.011 15.4 1.8 7.2 8 0 0 8 8 8 0 zinc-ribbon domain CNDH2_C PF16858.5 CEG41181.1 - 0.033 14.1 0.5 0.062 13.2 0.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SH3_6 PF12913.7 CEG41181.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) DNA_pol_B_thumb PF14791.6 CEG41182.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.6 1 1 0 1 1 1 0 DNA polymerase beta thumb PI3_PI4_kinase PF00454.27 CEG41184.1 - 1.7e-26 93.6 0.0 5.6e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE_2 PF02318.16 CEG41184.1 - 0.41 10.9 10.7 0.038 14.2 5.1 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger FYDLN_acid PF09538.10 CEG41184.1 - 1.7 9.3 4.8 12 6.7 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-CCHC_3 PF13917.6 CEG41185.1 - 7.9e-08 32.1 0.1 2.8e-07 30.4 0.1 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEG41185.1 - 0.038 14.1 1.0 0.069 13.3 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 CEG41185.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 CpXC protein PDZ_6 PF17820.1 CEG41190.1 - 2.7e-12 46.4 0.0 0.00033 20.4 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 CEG41190.1 - 1e-08 35.4 0.0 0.017 15.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Glyco_hydro_12 PF01670.16 CEG41192.1 - 3e-05 24.1 0.1 3.7e-05 23.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 BRE PF06113.12 CEG41197.1 - 6.2e-06 25.3 3.7 5.5e-05 22.2 3.8 2.0 1 1 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) B56 PF01603.20 CEG41198.1 - 1.2e-174 581.2 3.0 1.4e-174 580.9 3.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Melibiase_2_C PF17450.2 CEG41199.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain zf-RING_UBOX PF13445.6 CEG41200.1 - 9.5e-10 38.3 7.3 5e-09 36.0 7.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEG41200.1 - 2.7e-09 36.7 9.2 6.6e-09 35.5 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG41200.1 - 1.7e-08 34.2 7.5 3.4e-08 33.2 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41200.1 - 7.4e-08 32.6 9.8 1.6e-07 31.6 9.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEG41200.1 - 1.4e-07 31.5 8.1 3e-07 30.5 8.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG41200.1 - 3.8e-07 29.9 5.8 6.5e-07 29.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG41200.1 - 6.4e-07 29.2 6.5 1.5e-06 28.0 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CEG41200.1 - 0.0026 17.5 3.2 0.0061 16.4 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CEG41200.1 - 0.0027 17.5 7.9 0.03 14.2 7.8 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 FYVE PF01363.21 CEG41200.1 - 0.015 15.4 2.6 0.015 15.4 2.6 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-ANAPC11 PF12861.7 CEG41200.1 - 0.099 12.7 6.0 0.34 11.0 6.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CEG41200.1 - 0.15 12.0 2.3 0.34 10.8 2.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEG41200.1 - 0.35 11.2 10.6 1.8 8.9 10.5 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG41200.1 - 0.68 9.7 9.7 0.53 10.1 6.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-MIZ PF02891.20 CEG41200.1 - 9.2 6.1 10.2 23 4.9 10.2 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Complex1_LYR PF05347.15 CEG41201.1 - 1e-12 47.9 0.2 2.4e-12 46.7 0.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEG41201.1 - 0.00048 20.8 0.2 0.0012 19.6 0.1 1.5 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CEG41201.1 - 0.0028 18.2 0.1 0.0031 18.1 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like EAP30 PF04157.16 CEG41201.1 - 0.081 12.2 0.1 0.098 11.9 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family VPS11_C PF12451.8 CEG41203.1 - 1e-12 48.0 0.2 3e-12 46.5 0.2 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 CEG41203.1 - 1.6e-09 37.8 11.0 1.1e-06 28.6 0.3 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CEG41203.1 - 7.7e-05 22.6 9.5 7.7e-05 22.6 9.5 2.1 2 0 0 2 2 2 1 Zinc-finger Vps39_2 PF10367.9 CEG41203.1 - 0.00043 20.7 3.8 0.00063 20.2 2.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Chromosome_seg PF13889.6 CEG41203.1 - 0.025 14.8 0.3 0.075 13.2 0.3 1.8 1 0 0 1 1 1 0 Chromosome segregation during meiosis zf-rbx1 PF12678.7 CEG41203.1 - 0.076 13.3 5.8 0.18 12.1 5.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG41203.1 - 0.12 12.3 9.6 0.28 11.0 9.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41203.1 - 0.53 10.4 8.6 1.3 9.1 8.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Chromate_transp PF02417.15 CEG41205.1 - 2.1e-62 209.9 35.8 1.1e-36 126.4 18.2 2.4 2 1 0 2 2 2 2 Chromate transporter Phage_r1t_holin PF16945.5 CEG41205.1 - 0.077 13.2 0.4 0.077 13.2 0.4 2.6 3 0 0 3 3 3 0 Putative lactococcus lactis phage r1t holin AcrZ PF10766.9 CEG41205.1 - 2.4 7.8 9.4 0.51 9.9 0.7 3.7 3 0 0 3 3 3 0 Multidrug efflux pump-associated protein AcrZ Ncstrn_small PF18266.1 CEG41206.1 - 0.0071 16.4 0.0 0.0082 16.2 0.0 1.0 1 0 0 1 1 1 1 Nicastrin small lobe TFA2_Winged_2 PF18121.1 CEG41207.1 - 5.8 6.7 12.5 2.3 8.0 0.0 5.0 5 0 0 5 5 5 0 TFA2 Winged helix domain 2 MatE PF01554.18 CEG41208.1 - 8.9e-42 142.5 37.3 1.8e-21 76.5 13.6 2.4 2 1 0 2 2 2 2 MatE WD40 PF00400.32 CEG41209.1 - 1.2e-11 45.0 12.3 3.7e-06 27.5 0.1 8.3 9 1 1 10 10 9 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41209.1 - 1e-10 41.8 0.5 0.057 13.7 0.1 6.6 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 CEG41209.1 - 0.0015 18.5 19.5 0.29 11.3 0.3 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat Clathrin PF00637.20 CEG41209.1 - 0.0078 16.1 4.9 0.72 9.7 0.1 4.5 3 1 2 5 5 5 1 Region in Clathrin and VPS ANAPC3 PF12895.7 CEG41209.1 - 0.01 16.1 0.4 4.5 7.6 0.0 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_WDAD PF04053.14 CEG41209.1 - 0.04 13.0 12.4 7.2 5.5 0.2 5.5 5 1 1 6 6 6 0 Coatomer WD associated region WD40_3 PF15911.5 CEG41209.1 - 0.16 12.0 0.3 18 5.4 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_14 PF13428.6 CEG41209.1 - 0.28 12.1 17.8 29 5.8 0.1 6.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG41209.1 - 0.29 11.4 14.2 2.3 8.6 0.1 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG41209.1 - 0.51 10.7 7.6 0.5 10.7 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG41209.1 - 8.6 6.4 9.2 1.7 8.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Tub PF01167.18 CEG41210.1 - 1e-64 218.6 1.2 1.8e-63 214.5 0.1 2.2 2 0 0 2 2 2 1 Tub family DUF3527 PF12043.8 CEG41210.1 - 0.085 12.4 0.1 0.085 12.4 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3527) PI3K_1B_p101 PF10486.9 CEG41210.1 - 2 6.1 9.8 2.6 5.7 9.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpb1_3 PF04983.18 CEG41213.1 - 0.45 10.4 5.2 2.2 8.2 1.1 2.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 3 Tropomyosin PF00261.20 CEG41215.1 - 0.014 14.7 0.4 0.016 14.6 0.4 1.0 1 0 0 1 1 1 0 Tropomyosin Inositol_P PF00459.25 CEG41216.1 - 2.5e-35 122.3 0.0 3.8e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family EcKinase PF02958.20 CEG41216.1 - 5.7e-16 58.7 0.3 4e-15 55.9 0.3 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CEG41216.1 - 6.2e-07 28.6 0.4 9.9e-07 27.9 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 CEG41216.1 - 2.1e-06 27.8 1.0 2.1e-06 27.8 1.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEG41216.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PX PF00787.24 CEG41217.1 - 4.2e-08 33.2 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF5323 PF17257.2 CEG41217.1 - 0.21 11.5 0.8 0.8 9.6 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5323) PX PF00787.24 CEG41218.1 - 3.7e-08 33.3 0.0 5.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 PX domain GATase_4 PF13230.6 CEG41218.1 - 0.13 11.1 0.1 0.87 8.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Zip PF02535.22 CEG41219.1 - 8.7e-28 97.5 15.1 3.9e-27 95.3 15.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter MAJIN PF15077.6 CEG41220.1 - 0.16 11.7 1.4 0.22 11.3 1.4 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Fz PF01392.22 CEG41221.1 - 7.4e-08 33.0 3.1 1.7e-07 31.9 3.1 1.6 1 1 0 1 1 1 1 Fz domain SET PF00856.28 CEG41223.1 - 4.6e-12 46.6 0.0 4.6e-12 46.6 0.0 3.5 3 2 0 3 3 3 1 SET domain preSET_CXC PF18264.1 CEG41223.1 - 4.1e-10 39.9 15.9 4.1e-10 39.9 15.9 3.3 2 1 0 2 2 2 1 CXC domain TCR PF03638.15 CEG41223.1 - 0.0057 16.9 34.0 0.3 11.4 14.2 3.0 1 1 1 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain VKG_Carbox PF05090.14 CEG41223.1 - 0.24 10.2 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase MAT1 PF06391.13 CEG41228.1 - 1.3e-26 93.7 17.0 2e-26 93.1 17.0 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 CEG41228.1 - 1.2e-05 25.5 11.2 2.3e-05 24.6 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CEG41228.1 - 7.9e-05 22.4 9.9 0.00016 21.4 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG41228.1 - 0.00017 21.4 12.3 0.00031 20.6 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG41228.1 - 0.00021 21.2 14.0 0.00047 20.1 14.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEG41228.1 - 0.00089 19.4 3.0 0.00089 19.4 3.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEG41228.1 - 0.0012 18.6 13.2 0.0035 17.1 13.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG41228.1 - 0.0015 18.8 9.0 0.0032 17.7 9.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 CEG41228.1 - 0.0018 18.1 8.5 0.0018 18.1 8.5 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41228.1 - 0.0023 17.9 7.1 0.0048 16.9 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG41228.1 - 0.0029 17.4 14.6 0.012 15.4 14.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DNA_pol3_chi PF04364.13 CEG41228.1 - 0.0041 17.3 1.5 0.0087 16.2 0.2 2.1 1 1 1 2 2 2 1 DNA polymerase III chi subunit, HolC zf-ANAPC11 PF12861.7 CEG41228.1 - 0.013 15.5 4.6 0.031 14.3 4.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 CEG41228.1 - 0.28 11.2 11.3 15 5.7 11.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 CEG41228.1 - 0.93 9.3 12.7 4.9 7.0 13.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ALMT PF11744.8 CEG41228.1 - 2.7 6.7 9.1 3.8 6.2 9.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter IBR PF01485.21 CEG41228.1 - 7.5 6.9 12.1 8.4 6.7 8.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Glyco_hydro_59 PF02057.15 CEG41231.1 - 0.021 14.0 0.1 0.61 9.3 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 Exo_endo_phos PF03372.23 CEG41232.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEG41232.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase WD40 PF00400.32 CEG41234.1 - 1.2e-46 155.7 12.4 3.8e-07 30.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 CEG41234.1 - 1.2e-14 53.5 6.8 2.4e-14 52.6 6.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CEG41234.1 - 4.8e-12 46.0 0.4 0.007 16.6 0.0 5.4 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG41234.1 - 0.0047 16.3 0.0 0.56 9.5 0.0 3.3 3 1 1 4 4 4 1 WD40-like domain DUF4346 PF14251.6 CEG41234.1 - 0.099 12.7 0.1 0.65 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) PA PF02225.22 CEG41235.1 - 3.9e-09 36.4 0.0 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 PA domain PDZ PF00595.24 CEG41235.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 CEG41235.1 - 0.03 14.1 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Methyltransf_23 PF13489.6 CEG41236.1 - 2.3e-16 60.1 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG41236.1 - 3.3e-15 56.5 0.0 7.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG41236.1 - 1e-12 48.6 0.0 1.8e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG41236.1 - 1.5e-12 47.6 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG41236.1 - 2.2e-11 44.3 0.0 4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG41236.1 - 3e-08 33.3 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 CEG41236.1 - 2.7e-05 23.7 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CEG41236.1 - 0.0004 19.8 0.0 0.00055 19.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 CEG41236.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CEG41236.1 - 0.004 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CEG41236.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 CEG41236.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CEG41236.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.6 1 1 0 1 1 1 0 Lysine methyltransferase TRAPPC-Trs85 PF12739.7 CEG41237.1 - 3e-74 250.4 0.1 8.1e-74 249.0 0.0 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 CEG41237.1 - 0.086 10.2 0.0 0.12 9.7 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit FGGY_C PF02782.16 CEG41237.1 - 0.11 12.2 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Coatomer_WDAD PF04053.14 CEG41238.1 - 4.2e-120 401.8 0.0 6.1e-120 401.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CEG41238.1 - 1.3e-109 366.7 0.1 2.6e-109 365.6 0.1 1.5 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CEG41238.1 - 2.2e-38 129.5 20.6 3.4e-07 30.8 0.3 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat STIL_N PF15253.6 CEG41238.1 - 8.7e-20 71.0 0.0 8.7e-20 71.0 0.0 2.5 3 0 0 3 3 3 1 SCL-interrupting locus protein N-terminus ANAPC4_WD40 PF12894.7 CEG41238.1 - 6.6e-08 32.7 0.4 0.00031 21.0 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LINES_N PF14694.6 CEG41239.1 - 1.2e-16 61.2 1.6 2e-16 60.4 1.6 1.4 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 CEG41239.1 - 5.8e-12 44.8 0.3 2.3e-11 42.9 0.3 2.1 1 0 0 1 1 1 1 Lines C-terminus TetR_C_10 PF16295.5 CEG41239.1 - 0.1 12.9 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mei5 PF10376.9 CEG41239.1 - 0.18 11.7 0.4 0.36 10.7 0.4 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein CLTH PF10607.9 CEG41240.1 - 4.6e-27 94.7 1.9 6.3e-27 94.3 1.9 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CEG41240.1 - 5.4e-06 26.2 0.0 5.2e-05 23.0 0.0 2.5 3 0 0 3 3 3 1 LisH PX PF00787.24 CEG41241.1 - 2.4e-24 85.5 0.1 4.9e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CEG41241.1 - 2.2e-11 43.8 9.5 3.6e-11 43.1 9.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DUF2382 PF09557.10 CEG41241.1 - 0.19 12.0 0.9 0.44 10.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Neuroparsin PF07327.11 CEG41242.1 - 0.094 13.2 0.2 0.094 13.2 0.2 2.2 2 0 0 2 2 2 0 Neuroparsin C1_2 PF03107.16 CEG41242.1 - 3.5 8.0 9.0 0.27 11.6 2.0 2.4 2 0 0 2 2 2 0 C1 domain fn3 PF00041.21 CEG41244.1 - 0.1 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain CPSase_L_D2 PF02786.17 CEG41247.1 - 2.3e-102 341.0 0.1 3.3e-78 262.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 CEG41247.1 - 6.7e-49 166.2 0.0 7.7e-48 162.8 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CEG41247.1 - 2.6e-48 163.1 0.0 5.1e-48 162.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 CEG41247.1 - 3e-39 134.1 0.0 5.7e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 CEG41247.1 - 1.6e-14 53.9 0.0 1.3e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 CEG41247.1 - 3.9e-13 49.3 0.0 1.8e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CEG41247.1 - 3.4e-12 46.2 0.0 3e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CEG41247.1 - 9.7e-10 38.3 0.1 3.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 CEG41247.1 - 1e-05 25.4 0.2 0.0017 18.2 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CEG41247.1 - 0.00047 20.0 0.1 0.15 11.8 0.1 2.7 2 0 0 2 2 2 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 CEG41247.1 - 0.0012 18.9 0.1 0.8 9.7 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CEG41247.1 - 0.05 13.2 0.0 0.24 11.0 0.0 2.2 2 1 0 2 2 2 0 RimK-like ATP-grasp domain B12-binding PF02310.19 CEG41247.1 - 0.06 13.4 0.0 0.41 10.7 0.0 2.4 2 1 1 3 3 3 0 B12 binding domain TrkA_N PF02254.18 CEG41247.1 - 0.084 13.1 0.0 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain GARS_A PF01071.19 CEG41247.1 - 0.15 11.8 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Mitofilin PF09731.9 CEG41248.1 - 6.9e-54 183.8 50.2 1.4e-53 182.7 50.2 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein AAA_32 PF13654.6 CEG41248.1 - 0.043 12.6 35.9 0.066 12.0 21.8 2.7 1 1 2 3 3 3 0 AAA domain Octopine_DH PF02317.17 CEG41248.1 - 1.2 9.2 5.7 0.45 10.6 1.3 2.4 1 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain CbiA PF01656.23 CEG41250.1 - 0.00039 20.5 1.0 0.0012 18.9 1.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CEG41250.1 - 0.00086 18.8 1.1 0.0014 18.2 1.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 CEG41250.1 - 0.0018 17.5 0.9 0.0018 17.5 0.9 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase NACHT PF05729.12 CEG41250.1 - 0.012 15.5 0.2 0.091 12.7 0.1 2.1 1 1 1 2 2 2 0 NACHT domain NEL PF14496.6 CEG41250.1 - 0.03 13.7 0.4 0.03 13.7 0.4 1.7 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting NB-ARC PF00931.22 CEG41250.1 - 0.047 12.9 1.6 0.28 10.3 1.6 2.0 1 1 0 1 1 1 0 NB-ARC domain AAA_31 PF13614.6 CEG41250.1 - 0.16 11.9 2.5 0.33 10.8 1.7 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG41250.1 - 0.71 10.4 6.7 2.7 8.6 0.5 2.3 1 1 0 2 2 2 0 AAA domain Aminotran_5 PF00266.19 CEG41251.1 - 2.9e-09 36.4 0.0 3.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DCB PF16213.5 CEG41251.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF5098 PF17023.5 CEG41252.1 - 0.044 12.8 0.2 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Sec1 PF00995.23 CEG41253.1 - 8.4e-13 48.4 3.3 3.3e-11 43.1 0.1 2.4 2 1 0 2 2 2 2 Sec1 family HHH_8 PF14716.6 CEG41253.1 - 0.022 15.1 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Radial_spoke PF04712.12 CEG41255.1 - 5.5e-93 312.6 1.6 3.3e-56 191.2 0.0 2.2 1 1 1 2 2 2 2 Radial spokehead-like protein zf-RanBP PF00641.18 CEG41256.1 - 1.4e-11 43.5 59.8 2.4e-05 23.6 4.3 5.5 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others DZR PF12773.7 CEG41256.1 - 6.5 6.9 40.3 2.3 8.3 2.4 4.5 3 1 2 5 5 5 0 Double zinc ribbon Pkinase PF00069.25 CEG41257.1 - 1.1e-71 241.4 0.1 2.3e-71 240.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41257.1 - 4.5e-39 134.3 0.0 6.3e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG41257.1 - 0.00026 19.9 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEG41257.1 - 0.00057 19.3 0.1 0.84 8.9 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEG41257.1 - 0.0013 18.2 0.2 0.0027 17.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F420_oxidored PF03807.17 CEG41257.1 - 0.0014 19.1 0.0 0.0072 16.9 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1374 PF07118.11 CEG41257.1 - 0.0033 17.9 0.1 0.0076 16.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1374) ABC1 PF03109.16 CEG41257.1 - 0.027 14.6 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 ABC1 family Imm7 PF15585.6 CEG41257.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 RIO1 PF01163.22 CEG41257.1 - 0.1 12.2 2.3 0.44 10.1 2.3 1.8 1 1 0 1 1 1 0 RIO1 family tRNA-synt_2 PF00152.20 CEG41258.1 - 1.4e-82 277.3 0.0 1.7e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEG41258.1 - 5.3e-10 39.2 0.1 9.6e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEG41258.1 - 4.3e-09 36.2 0.3 7.8e-06 25.5 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-CCHC_4 PF14392.6 CEG41259.1 - 0.04 13.6 0.3 0.11 12.2 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Cullin PF00888.22 CEG41260.1 - 1.1e-24 87.0 1.7 1.8e-24 86.4 0.5 1.8 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 CEG41260.1 - 9.3e-20 70.9 0.3 1.2e-17 64.1 0.1 2.7 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TryThrA_C PF12319.8 CEG41260.1 - 0.042 13.3 0.2 0.076 12.5 0.2 1.3 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal HTH_10 PF04967.12 CEG41260.1 - 0.1 12.4 0.1 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 HTH DNA binding domain L27_N PF09060.10 CEG41262.1 - 0.049 13.7 1.9 0.62 10.2 0.0 2.6 2 0 0 2 2 2 0 L27_N ADK PF00406.22 CEG41264.1 - 1.4e-23 83.7 0.0 2.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG41264.1 - 1.6e-08 35.1 0.1 3.8e-07 30.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain MKT1_C PF12246.8 CEG41264.1 - 0.14 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_33 PF13671.6 CEG41264.1 - 0.64 10.2 3.6 14 5.8 0.0 3.0 1 1 1 3 3 3 0 AAA domain MCU PF04678.13 CEG41266.1 - 0.006 16.7 3.4 0.006 16.7 3.4 2.2 2 0 0 2 2 2 2 Mitochondrial calcium uniporter FumaraseC_C PF10415.9 CEG41266.1 - 0.022 15.2 3.0 0.32 11.5 0.0 3.4 2 1 1 3 3 3 0 Fumarase C C-terminus PWI PF01480.17 CEG41266.1 - 0.16 12.3 4.0 0.2 12.0 1.3 2.5 2 1 0 2 2 2 0 PWI domain Fucose_iso_N2 PF07882.12 CEG41266.1 - 4.6 6.8 12.3 0.048 13.2 1.8 2.0 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain SSXT PF05030.12 CEG41267.1 - 0.015 15.0 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) HECT PF00632.25 CEG41269.1 - 3.5e-90 302.6 0.0 9.3e-90 301.2 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Peptidase_C1 PF00112.23 CEG41269.1 - 0.0019 18.3 0.1 0.084 13.0 0.0 2.6 3 0 0 3 3 3 1 Papain family cysteine protease TBPIP PF07106.13 CEG41272.1 - 3.8e-20 71.6 0.3 7.1e-20 70.7 0.3 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CEG41272.1 - 4.5e-07 29.9 0.1 1.7e-06 28.0 0.1 2.1 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 CEG41272.1 - 0.007 16.7 0.2 0.048 14.0 0.0 2.2 1 1 1 2 2 2 1 Penicillinase repressor SesA PF17107.5 CEG41272.1 - 0.0075 16.5 1.6 0.0075 16.5 1.6 1.9 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3822 PF12864.7 CEG41272.1 - 0.019 14.2 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Seryl_tRNA_N PF02403.22 CEG41272.1 - 0.051 13.8 2.6 0.12 12.7 0.9 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Guanylate_cyc PF00211.20 CEG41272.1 - 0.088 12.4 0.9 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Nsp1_C PF05064.13 CEG41272.1 - 0.27 11.1 3.7 1 9.2 3.3 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Prefoldin_2 PF01920.20 CEG41272.1 - 0.53 10.3 5.4 1.2 9.2 0.9 2.6 1 1 1 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 CEG41272.1 - 3.9 8.0 9.2 0.066 13.7 1.6 2.0 3 0 0 3 3 3 0 Apg6 coiled-coil region CCD48 PF15799.5 CEG41272.1 - 7.4 4.8 8.2 0.33 9.2 0.1 2.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 48 adh_short PF00106.25 CEG41276.1 - 9.9e-17 61.0 0.0 4.6e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG41276.1 - 8e-10 38.7 0.0 2.7e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4158 PF13700.6 CEG41279.1 - 0.057 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Ank_5 PF13857.6 CEG41280.1 - 4.4e-12 46.0 0.7 5.3e-08 33.0 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41280.1 - 1e-11 45.2 0.0 1.5e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG41280.1 - 4.8e-10 39.8 0.3 1.8e-09 37.9 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41280.1 - 5.1e-09 35.7 0.2 0.0098 16.3 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CEG41280.1 - 5.5e-07 29.7 0.1 0.042 14.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 CEG41280.1 - 0.0031 18.0 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Methyltransf_16 PF10294.9 CEG41281.1 - 1.6e-24 86.6 0.3 2.5e-24 86.0 0.3 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG41281.1 - 1.1e-08 34.8 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG41281.1 - 3.1e-06 26.9 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG41281.1 - 0.0021 18.7 0.1 0.0052 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG41281.1 - 0.0025 17.6 0.2 0.0042 16.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEG41281.1 - 0.03 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein GidB PF02527.15 CEG41281.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Guanylate_kin PF00625.21 CEG41282.1 - 1.3e-29 103.2 0.0 2.9e-14 53.2 0.0 2.3 1 1 1 2 2 2 2 Guanylate kinase RsgA_GTPase PF03193.16 CEG41282.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CEG41282.1 - 0.00038 20.5 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CEG41282.1 - 0.00064 20.3 1.0 0.075 13.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG41282.1 - 0.00072 20.0 0.0 0.0029 18.0 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain RIIa PF02197.17 CEG41282.1 - 0.0011 18.6 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AAA_23 PF13476.6 CEG41282.1 - 0.013 16.0 0.4 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEG41282.1 - 0.013 16.0 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter dNK PF01712.19 CEG41282.1 - 0.015 15.2 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Methyltransf_12 PF08242.12 CEG41282.1 - 0.017 15.9 0.0 0.11 13.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain AAA_22 PF13401.6 CEG41282.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEG41282.1 - 0.033 14.3 0.1 3.1 7.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEG41282.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CEG41282.1 - 0.053 12.6 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 CEG41282.1 - 0.097 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 CEG41282.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CEG41282.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 CEG41282.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CEG41282.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_5 PF13857.6 CEG41283.1 - 2.2e-19 69.3 0.8 1.9e-09 37.6 0.5 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41283.1 - 2.7e-18 66.3 2.1 3e-13 50.1 0.3 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG41283.1 - 1.2e-14 54.4 0.3 3.2e-06 27.6 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41283.1 - 4.4e-11 42.0 0.7 0.0011 19.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEG41283.1 - 2.4e-07 30.9 1.4 0.00024 21.4 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 CEG41284.1 - 1.1e-08 35.3 5.5 1.1e-08 35.3 5.5 2.0 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG41284.1 - 2.3e-07 31.0 3.3 7.5e-07 29.3 3.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG41284.1 - 5.2e-06 26.3 6.1 1.7e-05 24.7 6.1 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEG41284.1 - 0.00011 21.9 6.0 0.00042 20.1 6.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG41284.1 - 0.00058 19.9 1.5 0.0016 18.4 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CEG41284.1 - 0.00071 19.4 5.8 0.00071 19.4 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41284.1 - 0.012 15.6 4.1 0.036 14.1 4.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 CEG41284.1 - 0.015 15.1 2.6 0.039 13.7 2.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger PWWP PF00855.17 CEG41284.1 - 0.025 15.0 0.1 0.025 15.0 0.1 2.8 2 1 0 2 2 2 0 PWWP domain zf-C3HC4_3 PF13920.6 CEG41284.1 - 0.028 14.3 5.2 0.078 12.9 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG41284.1 - 0.26 10.9 3.9 0.67 9.6 3.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEG41284.1 - 0.52 10.2 5.4 1.6 8.7 5.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CEG41284.1 - 1.9 8.4 5.5 0.27 11.1 1.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PWWP PF00855.17 CEG41285.1 - 2.6e-09 37.4 1.8 1e-08 35.5 1.8 2.1 1 0 0 1 1 1 1 PWWP domain DUF4708 PF15813.5 CEG41285.1 - 0.092 11.9 0.5 0.79 8.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4708) ThiF PF00899.21 CEG41288.1 - 4.3e-107 357.0 0.0 2.9e-71 239.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CEG41288.1 - 4.2e-80 269.3 0.0 6.3e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CEG41288.1 - 1.2e-29 102.8 0.1 2.8e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 CEG41288.1 - 7.4e-22 77.3 0.0 1.6e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 CEG41288.1 - 2.8e-18 65.9 0.0 6.8e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Shikimate_DH PF01488.20 CEG41288.1 - 0.0076 16.3 0.3 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IFRD PF05004.13 CEG41289.1 - 3.6e-55 187.2 3.5 5e-55 186.8 3.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 CEG41289.1 - 0.0013 18.8 1.4 0.062 13.6 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CEG41289.1 - 0.011 16.1 0.2 1.9 8.9 0.0 3.0 1 1 5 6 6 6 0 HEAT repeats DUF3385 PF11865.8 CEG41289.1 - 0.014 15.3 0.1 9.1 6.2 0.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) Tti2 PF10521.9 CEG41289.1 - 0.027 14.0 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Tti2 family Mga PF05043.13 CEG41289.1 - 0.032 14.8 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain Vac14_Fab1_bd PF12755.7 CEG41289.1 - 0.059 14.0 0.0 0.65 10.6 0.0 2.6 2 2 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEG41289.1 - 0.1 13.1 0.2 3.6 8.2 0.1 2.9 3 0 0 3 3 3 0 HEAT-like repeat OrfB_IS605 PF01385.19 CEG41289.1 - 0.13 12.5 0.5 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Probable transposase zf-CCCH PF00642.24 CEG41290.1 - 8.1e-08 32.0 2.3 8.1e-08 32.0 2.3 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CEG41290.1 - 0.00014 21.6 0.1 0.00022 21.0 0.1 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CEG41290.1 - 0.0036 17.3 2.3 0.0036 17.3 2.3 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEG41290.1 - 0.019 14.8 4.7 0.14 12.0 3.5 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CEG41290.1 - 0.029 15.1 0.2 0.06 14.0 0.2 1.5 1 0 0 1 1 1 0 Torus domain BLACT_WH PF17778.1 CEG41290.1 - 0.17 11.9 0.5 0.46 10.5 0.2 1.8 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain ABC2_membrane_3 PF12698.7 CEG41294.1 - 2.2e-60 204.6 46.1 6e-39 134.1 16.6 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CEG41294.1 - 3.6e-57 192.7 0.1 4.3e-27 95.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG41294.1 - 2.2e-19 70.4 3.1 1.7e-06 28.0 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEG41294.1 - 7e-06 26.0 0.1 0.18 11.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CEG41294.1 - 7.4e-05 23.3 5.0 0.0056 17.2 0.1 2.9 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CEG41294.1 - 0.00047 20.1 0.7 0.019 14.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 CEG41294.1 - 0.002 18.4 0.0 4.2 7.7 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CEG41294.1 - 0.0079 15.6 0.0 4.5 6.6 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG41294.1 - 0.0081 15.9 1.9 0.06 13.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane PF01061.24 CEG41294.1 - 0.013 14.9 48.0 0.008 15.6 21.4 4.4 4 0 0 4 4 4 0 ABC-2 type transporter MMR_HSR1 PF01926.23 CEG41294.1 - 0.02 15.0 0.2 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 CEG41294.1 - 0.06 13.0 2.7 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4162 PF13732.6 CEG41294.1 - 0.073 13.8 0.1 29 5.5 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 CEG41294.1 - 0.091 12.5 2.1 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEG41294.1 - 0.12 12.7 1.0 5.6 7.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 CEG41294.1 - 0.15 11.5 4.5 2.4 7.6 0.2 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_16 PF13191.6 CEG41294.1 - 0.18 12.2 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CEG41294.1 - 0.26 11.5 0.4 30 4.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MukB PF04310.12 CEG41294.1 - 0.33 10.7 2.2 4.3 7.1 0.2 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_24 PF13479.6 CEG41294.1 - 1.2 8.9 2.6 9.1 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CEG41295.1 - 3.6e-69 233.0 0.0 5.7e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41295.1 - 6e-34 117.5 0.1 1e-33 116.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG41295.1 - 6.2e-07 29.9 0.0 2.1e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG41295.1 - 7.8e-07 29.3 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CEG41295.1 - 0.0006 20.2 0.4 0.42 11.0 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Haspin_kinase PF12330.8 CEG41295.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG41295.1 - 0.024 14.0 0.2 0.051 12.9 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG41295.1 - 0.076 12.9 0.0 0.38 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.8 CEG41296.1 - 1.2e-35 123.3 0.1 1.6e-35 122.8 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CLASP_N PF12348.8 CEG41298.1 - 2.2e-24 86.3 0.4 6.9e-23 81.4 0.4 2.4 1 1 0 1 1 1 1 CLASP N terminal YabA PF06156.13 CEG41298.1 - 0.31 11.7 8.0 0.15 12.7 3.8 2.5 2 0 0 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 CEG41298.1 - 2 8.5 9.2 0.66 10.1 5.7 2.0 1 1 1 2 2 2 0 TolA binding protein trimerisation Folliculin PF11704.8 CEG41298.1 - 2.5 8.0 5.7 3.1 7.6 1.9 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CHORD PF04968.12 CEG41299.1 - 2.3e-43 146.7 22.4 1.6e-21 76.8 9.6 2.2 2 0 0 2 2 2 2 CHORD BTK PF00779.19 CEG41299.1 - 0.074 12.9 6.7 1.1 9.1 0.2 3.0 3 0 0 3 3 3 0 BTK motif Activin_recp PF01064.23 CEG41299.1 - 1.1 10.4 10.9 5.3 8.2 4.0 2.3 2 0 0 2 2 2 0 Activin types I and II receptor domain DUF374 PF04028.13 CEG41300.1 - 0.34 10.5 1.9 0.49 10.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF374) IHABP4_N PF16174.5 CEG41300.1 - 2.5 8.7 7.9 1.2 9.7 2.7 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Peptidase_S74 PF13884.6 CEG41301.1 - 0.0096 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase FBPase_glpX PF03320.13 CEG41301.1 - 0.15 10.9 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Pox_A32 PF04665.12 CEG41303.1 - 0.00087 18.8 0.2 0.00092 18.7 0.2 1.0 1 0 0 1 1 1 1 Poxvirus A32 protein Pmp3 PF01679.17 CEG41305.1 - 4.5e-21 74.8 3.2 5.5e-21 74.5 3.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.17 CEG41306.1 - 2.4e-21 75.7 5.6 2.7e-21 75.5 5.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Spt4 PF06093.13 CEG41309.1 - 3.6e-33 113.5 1.3 4.7e-33 113.1 1.3 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger HIPIP PF01355.17 CEG41309.1 - 0.3 11.5 4.4 0.31 11.4 1.4 2.0 1 1 1 2 2 2 0 High potential iron-sulfur protein rve PF00665.26 CEG41311.1 - 6.7e-08 32.7 0.1 8.8e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1744 PF08490.12 CEG41313.1 - 8.9e-98 327.5 0.0 1.8e-97 326.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CEG41313.1 - 2.1e-64 217.8 1.1 3.4e-64 217.1 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CEG41313.1 - 1.6e-13 50.2 0.1 4.6e-11 42.1 0.1 3.4 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CEG41313.1 - 9e-08 32.0 0.3 2.3e-07 30.7 0.3 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CEG41313.1 - 5.1e-05 23.3 0.2 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily AhpC-TSA PF00578.21 CEG41314.1 - 2.4e-37 127.6 0.0 3.1e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEG41314.1 - 3.1e-14 52.9 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEG41314.1 - 7.1e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin BSD PF03909.17 CEG41315.1 - 9.7e-07 28.7 0.0 2.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 BSD domain Baculo_PEP_C PF04513.12 CEG41315.1 - 0.093 12.8 2.0 6 6.9 0.5 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 CEG41315.1 - 0.23 12.0 12.6 0.75 10.4 0.0 3.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal RXLR PF16810.5 CEG41317.1 - 2.8e-05 24.6 0.1 5e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity gag_pre-integrs PF13976.6 CEG41322.1 - 0.0044 16.9 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C6H2 PF15801.5 CEG41323.1 - 0.013 15.8 0.3 0.022 15.0 0.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ANAPC3 PF12895.7 CEG41324.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Lactamase_B_2 PF12706.7 CEG41325.1 - 3.3e-08 33.3 0.6 6e-08 32.4 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEG41325.1 - 0.0019 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 CEG41325.1 - 0.0043 16.2 0.2 0.012 14.8 0.1 1.8 2 0 0 2 2 2 1 cAMP phosphodiesterases class-II MFS_1 PF07690.16 CEG41326.1 - 9.6e-12 44.5 19.0 9.6e-12 44.5 19.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG41326.1 - 3.4e-06 26.2 4.7 3.4e-06 26.2 4.7 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter DUF3810 PF12725.7 CEG41326.1 - 0.008 15.6 0.7 0.008 15.6 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3810) DUF5337 PF17272.2 CEG41326.1 - 0.76 9.6 7.8 0.38 10.6 0.9 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) RVT_2 PF07727.14 CEG41327.1 - 2e-44 152.1 0.0 2.8e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HlyD_D23 PF16576.5 CEG41327.1 - 0.039 13.2 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Thiolase_C PF02803.18 CEG41328.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain IstB_IS21 PF01695.17 CEG41330.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4203 PF13886.6 CEG41331.1 - 4.5e-45 153.8 26.3 5.7e-45 153.5 26.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Trp_oprn_chp PF09534.10 CEG41331.1 - 0.069 12.9 0.9 1.3 8.8 0.0 2.7 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_trans_4_2 PF13477.6 CEG41331.1 - 0.16 12.0 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Phage_holin_5_1 PF06946.11 CEG41331.1 - 0.53 10.7 13.8 2.9 8.3 1.4 2.8 1 1 1 3 3 3 0 Bacteriophage A118-like holin, Hol118 ZapB PF06005.12 CEG41334.1 - 4 8.0 20.7 2.9 8.4 0.9 3.9 3 0 0 3 3 3 0 Cell division protein ZapB DUF2428 PF10350.9 CEG41335.1 - 4.3e-49 167.2 0.5 1.8e-48 165.2 0.0 2.4 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CEG41335.1 - 0.015 15.5 4.3 1.9 8.9 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 CEG41335.1 - 0.018 15.4 11.1 2.4 8.6 0.1 5.0 5 0 0 5 5 5 0 HEAT repeats Barstar PF01337.18 CEG41335.1 - 0.12 12.4 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Ipi1_N PF12333.8 CEG41335.1 - 3.1 8.5 6.1 4.9 7.8 0.0 4.3 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Aa_trans PF01490.18 CEG41338.1 - 8.9e-50 169.6 16.3 1.1e-49 169.3 16.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_5 PF13857.6 CEG41339.1 - 4.1e-16 58.8 2.4 1.2e-07 31.9 0.3 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41339.1 - 7e-15 55.4 0.8 1.2e-10 41.8 0.8 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG41339.1 - 1.5e-12 46.5 0.1 0.0011 19.2 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CEG41339.1 - 1.6e-10 41.3 0.7 0.00045 20.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG41339.1 - 2.5e-10 40.3 5.2 3e-05 24.3 0.4 4.0 4 0 0 4 4 4 2 Ankyrin repeat FYVE PF01363.21 CEG41339.1 - 0.0048 17.0 12.6 0.01 16.0 12.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 CEG41339.1 - 0.018 15.2 1.9 0.018 15.2 1.9 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FYVE_2 PF02318.16 CEG41339.1 - 4 7.7 11.9 11 6.3 11.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger HHH PF00633.23 CEG41340.1 - 0.0025 17.6 0.1 0.0063 16.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CEG41340.1 - 0.045 14.4 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain FlxA PF14282.6 CEG41341.1 - 0.0021 18.0 5.2 0.0021 18.0 5.2 2.6 2 0 0 2 2 2 1 FlxA-like protein ATG16 PF08614.11 CEG41341.1 - 0.017 15.4 27.1 0.042 14.1 11.1 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 CEG41341.1 - 0.34 9.9 21.2 0.2 10.7 11.9 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 CEG41341.1 - 0.47 10.9 8.5 31 5.1 0.1 4.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 CEG41341.1 - 0.59 10.5 23.5 0.086 13.2 8.4 3.8 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 HALZ PF02183.18 CEG41341.1 - 1.9 8.8 14.0 0.74 10.1 0.1 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper HemX PF04375.14 CEG41341.1 - 2.5 7.3 20.0 2.6 7.2 5.4 2.4 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF16 PF01519.16 CEG41341.1 - 3.1 8.3 16.3 0.92 10.0 1.5 3.6 3 2 1 4 4 4 0 Protein of unknown function DUF16 Fez1 PF06818.15 CEG41341.1 - 4.3 7.7 34.1 1.2 9.5 7.2 3.4 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 CEG41341.1 - 8.9 6.8 31.9 0.84 10.2 4.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region LRAT PF04970.13 CEG41343.1 - 2.1e-07 31.3 0.0 5.2e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Lecithin retinol acyltransferase IBR PF01485.21 CEG41344.1 - 8e-18 64.4 44.0 1.1e-08 35.2 14.4 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CEG41344.1 - 2.3e-06 27.4 1.1 2.3e-06 27.4 1.1 5.0 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41344.1 - 1.2e-05 25.3 1.5 1.2e-05 25.3 1.5 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEG41344.1 - 0.00048 20.4 6.4 0.00048 20.4 6.4 4.9 4 2 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG41344.1 - 0.0033 17.2 0.6 0.0033 17.2 0.6 6.3 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG41344.1 - 0.029 14.5 0.2 0.029 14.5 0.2 5.7 4 2 1 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_14 PF17978.1 CEG41344.1 - 0.036 14.5 0.7 0.036 14.5 0.7 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Seipin PF06775.14 CEG41345.1 - 1.3e-50 172.3 5.0 2e-50 171.6 5.0 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) RIO1 PF01163.22 CEG41346.1 - 1.2e-59 201.1 0.3 3.7e-59 199.5 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CEG41346.1 - 1.5e-05 24.0 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CEG41346.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEG41346.1 - 5.2e-05 22.7 1.3 8.3e-05 22.0 0.3 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG41346.1 - 0.0013 18.7 0.1 0.0056 16.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEG41346.1 - 0.0039 16.8 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 CEG41346.1 - 0.0053 16.1 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PA26 PF04636.13 CEG41347.1 - 1e-118 397.1 0.0 1.5e-118 396.6 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Tyrosinase PF00264.20 CEG41347.1 - 0.019 15.3 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Common central domain of tyrosinase P22_portal PF16510.5 CEG41349.1 - 0.036 12.7 10.3 0.035 12.7 10.3 1.0 1 0 0 1 1 1 0 Phage P22-like portal protein DUF3450 PF11932.8 CEG41349.1 - 0.3 10.4 11.0 0.39 10.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMP_2 PF06791.13 CEG41349.1 - 0.68 9.6 14.5 0.83 9.3 14.5 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein HABP4_PAI-RBP1 PF04774.15 CEG41349.1 - 0.73 10.7 6.7 0.9 10.4 6.7 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Zn-C2H2_12 PF18112.1 CEG41351.1 - 0.0073 16.7 2.8 0.34 11.4 0.3 3.1 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain GNAT_acetyltr_2 PF13718.6 CEG41352.1 - 0.063 12.7 0.5 0.13 11.7 0.5 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF1700 PF08006.11 CEG41352.1 - 0.98 8.9 3.5 1.6 8.2 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Glyoxalase PF00903.25 CEG41353.1 - 0.00019 21.6 0.0 0.00045 20.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CEG41353.1 - 0.00023 21.0 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 CEG41353.1 - 0.048 14.5 0.0 0.071 13.9 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain CCCAP PF15964.5 CEG41353.1 - 0.31 9.3 0.0 0.38 9.0 0.0 1.0 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family LRR_4 PF12799.7 CEG41355.1 - 2e-05 24.9 41.4 0.013 15.9 2.6 7.1 5 1 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG41355.1 - 2.3 8.1 23.7 1.4 8.7 3.5 5.7 4 2 0 4 4 4 0 Leucine rich repeat Ank_5 PF13857.6 CEG41356.1 - 6.6e-16 58.2 0.1 1.9e-10 40.8 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41356.1 - 1.5e-14 54.3 0.0 1.4e-06 28.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 CEG41356.1 - 5.4e-13 48.6 10.3 5.4e-13 48.6 10.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 CEG41356.1 - 6e-13 49.0 0.1 1.7e-11 44.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41356.1 - 1.2e-10 40.7 0.1 0.0024 18.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEG41356.1 - 9.1e-09 35.4 0.8 0.0022 18.4 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeat zf-RING_2 PF13639.6 CEG41356.1 - 3.9e-07 30.3 9.8 3.9e-07 30.3 9.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG41356.1 - 2.4e-05 24.1 11.0 7.2e-05 22.6 11.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG41356.1 - 5.7e-05 22.9 10.0 0.00013 21.8 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CEG41356.1 - 0.0045 16.9 9.7 0.0045 16.9 9.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG41356.1 - 0.01 15.9 5.1 0.041 13.9 3.1 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CEG41356.1 - 0.017 15.3 10.3 0.066 13.4 10.3 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PH PF00169.29 CEG41356.1 - 0.048 14.2 0.1 0.14 12.7 0.1 1.8 1 1 0 1 1 1 0 PH domain zf-RING_4 PF14570.6 CEG41356.1 - 0.086 12.7 7.6 0.26 11.1 7.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CEG41356.1 - 0.81 9.8 8.2 0.45 10.6 1.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF3293 PF11697.8 CEG41357.1 - 0.038 14.5 0.1 0.14 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) DUF4441 PF14536.6 CEG41357.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4441) tify PF06200.14 CEG41359.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 tify domain Elf1 PF05129.13 CEG41361.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ras PF00071.22 CEG41363.1 - 6.1e-52 175.5 0.0 8.4e-52 175.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG41363.1 - 7.3e-33 113.3 0.0 1.3e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG41363.1 - 1.9e-15 56.7 0.0 3.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG41363.1 - 4.9e-07 29.3 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG41363.1 - 5.3e-05 23.2 0.0 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG41363.1 - 9.8e-05 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG41363.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG41363.1 - 0.037 14.4 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 CEG41363.1 - 0.039 13.1 0.4 0.32 10.1 0.1 2.2 1 1 2 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 CEG41363.1 - 0.041 14.4 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 CEG41363.1 - 0.047 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 CEG41363.1 - 0.054 12.9 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein MCM2_N PF12619.8 CEG41363.1 - 1.6 9.0 5.3 6.2 7.1 5.3 2.0 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 DUF3767 PF12597.8 CEG41364.1 - 3.7e-15 55.6 0.2 4.5e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ubiquitin PF00240.23 CEG41366.1 - 1.4e-16 60.0 0.1 2.7e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family SNARE_assoc PF09335.11 CEG41366.1 - 1.9e-13 50.9 1.5 4.4e-13 49.8 1.5 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Rad60-SLD PF11976.8 CEG41366.1 - 3e-05 23.8 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CEG41366.1 - 0.23 11.4 1.0 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain UQ_con PF00179.26 CEG41367.1 - 4.5e-44 149.5 0.0 5.6e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 CEG41367.1 - 4.7e-08 32.8 0.1 8.3e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 CEG41367.1 - 7.5e-06 25.7 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CEG41367.1 - 0.0018 18.6 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain AAA_11 PF13086.6 CEG41368.1 - 8.5e-65 219.1 4.2 8.5e-65 219.1 4.2 3.5 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 CEG41368.1 - 9.6e-54 182.0 0.1 9.6e-54 182.0 0.1 2.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 CEG41368.1 - 8e-15 55.1 0.0 3.2e-13 49.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CEG41368.1 - 3.6e-10 40.0 0.8 3.8e-07 30.1 0.2 3.7 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 CEG41368.1 - 6.5e-10 39.3 0.0 5.8e-09 36.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CEG41368.1 - 3.5e-08 33.9 3.1 7.6e-08 32.8 0.2 3.0 2 2 0 2 2 2 1 AAA domain zf-AN1 PF01428.16 CEG41368.1 - 2e-07 31.0 2.7 4.4e-07 30.0 2.7 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 CEG41368.1 - 3.2e-07 30.3 3.5 0.056 13.2 0.0 4.2 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CEG41368.1 - 1.3e-06 28.3 2.2 6.8e-06 26.0 0.1 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG41368.1 - 0.0001 22.6 0.3 0.0011 19.2 0.3 2.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEG41368.1 - 0.00015 20.9 0.3 0.00049 19.3 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 CEG41368.1 - 0.00029 21.3 2.0 0.0096 16.3 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CEG41368.1 - 0.00052 19.4 9.0 0.0025 17.1 3.7 3.3 2 1 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CEG41368.1 - 0.0006 20.2 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 CEG41368.1 - 0.00063 19.2 0.1 0.003 17.0 0.1 2.1 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 CEG41368.1 - 0.00063 19.4 1.4 0.00063 19.4 1.4 3.1 2 2 0 2 2 1 1 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 CEG41368.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 CEG41368.1 - 0.0077 16.2 0.2 0.073 13.0 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain ATPase PF06745.13 CEG41368.1 - 0.0089 15.4 0.4 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 KaiC ATPase_2 PF01637.18 CEG41368.1 - 0.012 15.6 3.3 0.23 11.4 3.3 2.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CEG41368.1 - 0.014 15.9 0.5 0.014 15.9 0.5 2.7 2 1 0 2 2 1 0 ABC transporter AAA_25 PF13481.6 CEG41368.1 - 0.017 14.7 0.2 0.15 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG41368.1 - 0.021 15.0 0.6 0.069 13.3 0.0 2.4 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 CEG41368.1 - 0.027 14.9 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 1 0 RNA helicase Flavi_DEAD PF07652.14 CEG41368.1 - 0.031 14.2 1.5 0.34 10.9 0.0 2.8 1 1 1 2 2 2 0 Flavivirus DEAD domain Mg_chelatase PF01078.21 CEG41368.1 - 0.034 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_26 PF13500.6 CEG41368.1 - 0.043 13.6 1.8 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CEG41368.1 - 0.05 14.1 13.8 0.95 9.9 3.8 3.9 2 2 0 2 2 2 0 AAA domain Glyco_transf_21 PF13506.6 CEG41368.1 - 0.072 12.6 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 NACHT PF05729.12 CEG41368.1 - 0.089 12.7 0.1 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 CEG41368.1 - 0.33 10.6 0.0 0.33 10.6 0.0 3.4 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Na_Ca_ex PF01699.24 CEG41369.1 - 1.5e-12 47.8 28.9 2.8e-10 40.3 13.2 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 CEG41369.1 - 3.7e-12 46.5 0.4 9.9e-12 45.1 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG41369.1 - 2.7e-09 35.9 0.2 0.00038 19.8 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG41369.1 - 8.2e-08 31.6 0.2 0.005 16.7 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG41369.1 - 0.00036 19.9 0.6 0.043 13.3 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CEG41369.1 - 0.04 13.8 0.1 0.088 12.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair V-SNARE PF05008.15 CEG41370.1 - 8.8e-08 32.4 16.2 2.9e-07 30.7 7.0 2.2 2 0 0 2 2 2 2 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CEG41370.1 - 7.8e-05 22.9 2.2 7.8e-05 22.9 2.2 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SabA_adhesion PF18304.1 CEG41370.1 - 0.0045 16.3 1.9 0.0045 16.3 1.9 1.4 1 1 0 1 1 1 1 SabA N-terminal extracellular adhesion domain CwsA PF10814.8 CEG41370.1 - 0.022 15.0 1.7 0.045 13.9 1.7 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA FUSC PF04632.12 CEG41370.1 - 0.043 12.4 7.9 0.05 12.1 7.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliJ PF02050.16 CEG41370.1 - 0.05 13.8 19.3 0.13 12.5 8.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4549 PF15082.6 CEG41370.1 - 0.068 13.0 1.6 0.12 12.1 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) Pex24p PF06398.11 CEG41370.1 - 0.16 10.9 0.5 0.24 10.3 0.4 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF745 PF05335.13 CEG41370.1 - 0.17 11.6 15.3 0.26 11.0 7.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF148 PF02520.17 CEG41370.1 - 0.2 11.7 11.7 0.043 13.9 4.9 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 ALMT PF11744.8 CEG41370.1 - 0.29 9.9 6.5 0.35 9.7 6.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter HIP1_clath_bdg PF16515.5 CEG41370.1 - 0.35 11.5 17.4 0.096 13.3 4.9 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF725 PF05267.12 CEG41370.1 - 0.42 10.6 5.3 0.65 10.0 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF725) DUF2408 PF10303.9 CEG41370.1 - 0.52 10.9 7.3 0.86 10.2 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CREPT PF16566.5 CEG41370.1 - 0.76 9.9 14.4 3.5 7.8 6.9 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Dor1 PF04124.12 CEG41370.1 - 0.85 8.2 10.7 0.064 11.9 2.9 2.1 1 1 1 2 2 2 0 Dor1-like family DUF1043 PF06295.12 CEG41370.1 - 1.3 9.1 8.2 0.46 10.5 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 CEG41370.1 - 1.9 8.6 8.7 1.9 8.6 2.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CEG41370.1 - 2.2 7.4 10.4 0.42 9.8 0.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 CEG41370.1 - 2.4 8.3 11.2 1.2 9.3 7.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CEG41370.1 - 4.2 7.4 14.6 1.8 8.6 2.3 2.6 1 1 2 3 3 3 0 Laminin Domain II XhlA PF10779.9 CEG41370.1 - 5 7.4 7.9 17 5.7 0.5 3.4 2 2 2 4 4 4 0 Haemolysin XhlA LRR_4 PF12799.7 CEG41371.1 - 4.6e-19 68.2 10.8 0.00038 20.8 0.2 5.6 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG41371.1 - 2.5e-18 65.6 17.3 9.2e-10 38.1 0.1 5.3 3 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 CEG41371.1 - 6.2e-09 35.2 14.4 0.85 9.8 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 CEG41371.1 - 3.4e-06 26.9 11.9 1.3 9.9 0.1 8.2 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 CEG41371.1 - 0.02 14.4 5.8 0.1 12.1 1.2 3.5 2 1 2 4 4 4 0 Leucine-rich repeat H2O2_YaaD PF03883.14 CEG41371.1 - 0.067 12.7 0.4 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Peroxide stress protein YaaA MINDY_DUB PF04424.13 CEG41371.1 - 0.1 12.7 0.2 0.64 10.0 0.0 2.4 2 0 0 2 2 2 0 MINDY deubiquitinase WD40 PF00400.32 CEG41372.1 - 1.6e-10 41.4 0.2 0.1 13.5 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41372.1 - 1.8e-05 24.9 0.0 5.3 7.4 0.0 4.9 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CEG41372.1 - 0.0033 16.0 0.1 0.016 13.7 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain S19 PF06756.11 CEG41372.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Chorion protein S19 C-terminal RloB PF13707.6 CEG41373.1 - 1.1 9.4 5.8 2.2 8.4 5.8 1.7 1 1 0 1 1 1 0 RloB-like protein HicB PF05534.12 CEG41374.1 - 0.13 12.1 0.2 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 HicB family Dimer_Tnp_hAT PF05699.14 CEG41375.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4110 PF13422.6 CEG41376.1 - 9.3e-19 67.3 0.1 9.3e-19 67.3 0.1 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 CEG41376.1 - 2.5e-13 50.0 0.1 0.39 11.1 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG41376.1 - 1.6e-09 37.7 0.8 5.8e-05 23.2 0.0 3.2 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CEG41376.1 - 0.0002 21.3 3.5 0.31 11.1 0.2 4.0 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG41376.1 - 0.00027 20.8 0.2 0.72 9.9 0.0 4.1 4 0 0 4 4 4 1 Kelch motif DUF5026 PF16429.5 CEG41376.1 - 0.0085 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5026) Kelch_1 PF01344.25 CEG41376.1 - 0.036 13.7 3.3 7.3 6.3 0.0 3.8 3 1 0 3 3 3 0 Kelch motif Chromo PF00385.24 CEG41377.1 - 4.1e-08 33.0 0.2 6.2e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UCH PF00443.29 CEG41380.1 - 5.7e-57 193.1 0.3 1.2e-56 192.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG41380.1 - 2.7e-22 79.8 1.6 2.7e-22 79.8 1.6 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DevR PF01905.16 CEG41380.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated negative auto-regulator DevR/Csa2 CpXC PF14353.6 CEG41380.1 - 0.11 12.5 0.7 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 CpXC protein Rubredoxin_2 PF18073.1 CEG41380.1 - 2.3 8.0 5.1 17 5.2 0.8 2.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain IQ PF00612.27 CEG41381.1 - 0.00023 20.7 0.0 0.00076 19.1 0.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Poxvirus_B22R PF04395.12 CEG41381.1 - 0.062 12.8 2.5 0.13 11.8 2.5 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein DUF848 PF05852.11 CEG41381.1 - 0.21 11.7 5.9 1.7 8.7 4.4 2.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Ank_2 PF12796.7 CEG41382.1 - 0.0004 20.9 0.2 0.03 14.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG41382.1 - 0.003 17.9 0.1 7.6 7.5 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CEG41382.1 - 0.0077 16.8 0.6 0.58 10.8 0.0 3.8 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG41382.1 - 0.14 12.5 0.3 9.3 6.7 0.0 3.2 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF4287 PF14117.6 CEG41382.1 - 0.23 11.6 1.9 19 5.5 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4287) Ank_4 PF13637.6 CEG41383.1 - 5.1e-27 93.9 16.9 2e-07 31.4 0.2 7.4 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41383.1 - 4.4e-24 84.9 15.4 1.3e-07 32.1 0.5 4.4 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG41383.1 - 1.6e-18 66.5 16.0 0.001 19.3 0.1 9.2 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41383.1 - 1.7e-12 46.3 8.0 5.6 7.9 0.0 9.6 10 0 0 10 10 10 1 Ankyrin repeat DUF1979 PF09322.10 CEG41383.1 - 0.00029 20.7 0.2 0.86 9.6 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1979) Ank PF00023.30 CEG41383.1 - 0.0019 18.6 4.1 76 4.0 0.0 7.0 5 2 3 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 CEG41383.1 - 0.0026 17.6 0.0 19 5.3 0.0 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) DUF249 PF03158.13 CEG41383.1 - 0.022 14.5 3.0 4.1 7.1 0.1 3.9 1 1 4 5 5 5 0 Multigene family 530 protein FBD PF08387.10 CEG41383.1 - 0.056 13.3 0.9 29 4.6 0.2 4.5 5 1 0 5 5 5 0 FBD DUF4224 PF13986.6 CEG41383.1 - 0.15 12.0 0.3 3.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Aminotran_1_2 PF00155.21 CEG41385.1 - 0.099 11.8 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II GP70 PF17429.2 CEG41387.1 - 0.032 14.1 0.3 0.083 12.7 0.3 1.7 1 0 0 1 1 1 0 Gene product 70 DUF3959 PF13105.6 CEG41387.1 - 1.2 8.5 3.4 3.1 7.2 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) MMR_HSR1 PF01926.23 CEG41388.1 - 9.5e-15 54.7 0.0 9.6e-13 48.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG41388.1 - 2.5e-07 30.4 0.0 8.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG41388.1 - 0.00012 22.1 2.3 0.0057 16.6 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CEG41388.1 - 0.0034 16.7 0.6 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family MeaB PF03308.16 CEG41388.1 - 0.029 13.4 0.0 0.07 12.1 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CEG41388.1 - 0.043 13.9 1.2 0.18 11.8 0.0 2.6 4 0 0 4 4 4 0 Dynamin family cobW PF02492.19 CEG41388.1 - 0.07 12.7 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 CEG41389.1 - 7.8e-71 238.5 0.0 9.4e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41389.1 - 4.6e-35 121.2 0.0 6.1e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEG41389.1 - 5.4e-08 33.4 2.5 1.2e-07 32.3 2.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CEG41389.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEG41389.1 - 0.0032 17.1 0.3 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEG41389.1 - 0.0068 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG41389.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG41389.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CATSPERD PF15020.6 CEG41389.1 - 0.16 10.2 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta MMR_HSR1 PF01926.23 CEG41391.1 - 3.9e-21 75.2 0.2 1e-20 73.9 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG41391.1 - 2.2e-09 37.1 0.0 4.3e-07 29.7 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CEG41391.1 - 2e-08 33.9 0.7 7e-07 28.9 0.6 2.3 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEG41391.1 - 2.3e-07 31.0 5.7 0.0034 17.5 0.1 2.9 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CEG41391.1 - 3.6e-06 27.0 0.3 0.033 14.1 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CEG41391.1 - 4e-06 26.3 0.1 6.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 AIG1 family KH_2 PF07650.17 CEG41391.1 - 4.9e-06 26.3 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 KH domain Arf PF00025.21 CEG41391.1 - 5.2e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 CEG41391.1 - 0.00014 21.4 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein ATP_bind_1 PF03029.17 CEG41391.1 - 0.00024 21.0 0.4 0.0029 17.4 0.6 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 CEG41391.1 - 0.0019 18.4 0.0 0.006 16.8 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEG41391.1 - 0.0041 16.7 0.5 0.014 15.0 0.3 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MnmE_helical PF12631.7 CEG41391.1 - 0.0061 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 MnmE helical domain AAA_22 PF13401.6 CEG41391.1 - 0.035 14.4 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CEG41391.1 - 0.043 13.2 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PAC3 PF10178.9 CEG41393.1 - 1.2e-16 60.7 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Ras PF00071.22 CEG41394.1 - 7.6e-57 191.4 0.3 8.8e-57 191.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG41394.1 - 7.5e-35 119.7 0.1 1.1e-34 119.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG41394.1 - 1.3e-16 60.6 0.2 1.8e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG41394.1 - 6.3e-06 25.7 0.1 7.6e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG41394.1 - 6.3e-05 23.0 0.1 0.00011 22.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG41394.1 - 0.00015 21.4 0.3 0.00057 19.5 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEG41394.1 - 0.00057 19.4 0.1 0.0011 18.5 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit VirE PF05272.11 CEG41394.1 - 0.018 14.8 0.3 0.093 12.5 0.1 2.1 2 0 0 2 2 2 0 Virulence-associated protein E RsgA_GTPase PF03193.16 CEG41394.1 - 0.042 13.7 0.4 0.91 9.4 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CEG41394.1 - 0.042 14.2 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CEG41394.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin DUF4226 PF10774.9 CEG41394.1 - 0.16 12.3 0.0 0.63 10.3 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4226) NUDIX_2 PF13869.6 CEG41398.1 - 0.16 11.6 0.1 0.23 11.0 0.1 1.4 1 1 0 1 1 1 0 Nucleotide hydrolase Med20 PF08612.11 CEG41400.1 - 4.3e-15 55.7 0.0 5.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Biotin_lipoyl PF00364.22 CEG41402.1 - 6.1e-20 70.8 3.1 8.3e-20 70.4 3.1 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 CEG41402.1 - 5.5e-05 23.1 0.9 9.3e-05 22.3 0.9 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 CEG41402.1 - 0.00049 20.8 2.4 0.052 14.3 0.1 2.3 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 CEG41402.1 - 0.0025 17.6 4.3 0.028 14.2 0.2 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like PYNP_C PF07831.13 CEG41402.1 - 0.018 14.7 0.6 5.4 6.7 0.2 2.3 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CEG41402.1 - 0.024 13.8 0.1 0.094 11.9 0.0 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Methyltransf_19 PF04672.12 CEG41402.1 - 0.025 14.1 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase RnfC_N PF13375.6 CEG41402.1 - 0.076 13.0 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain S36_mt PF10937.8 CEG41402.1 - 0.11 14.1 0.7 12 7.5 0.1 2.8 2 1 1 3 3 3 0 Ribosomal protein S36, mitochondrial Ank_2 PF12796.7 CEG41403.1 - 5.2e-36 123.1 16.3 3.6e-08 33.9 0.1 8.0 1 1 7 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG41403.1 - 3.3e-34 116.8 29.7 9e-06 26.1 0.2 11.2 7 2 5 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG41403.1 - 1.3e-23 82.8 29.1 0.0077 16.5 0.2 14.4 3 3 12 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41403.1 - 9e-20 68.7 11.0 0.96 10.2 0.0 14.7 13 2 3 16 16 16 3 Ankyrin repeat DUF3322 PF11795.8 CEG41403.1 - 0.00021 21.4 5.5 0.94 9.5 0.1 5.0 3 2 2 5 5 5 2 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF5049 PF16468.5 CEG41403.1 - 0.00028 20.7 0.1 20 5.2 0.0 6.7 6 3 3 9 9 9 0 Domain of unknown function (DUF5049) DUF1843 PF08898.10 CEG41403.1 - 0.00055 20.4 8.6 47 4.6 0.0 8.7 10 0 0 10 10 10 0 Domain of unknown function (DUF1843) AbiEi_3_N PF17194.4 CEG41403.1 - 0.00077 19.4 1.6 2.6 8.1 0.0 5.3 5 1 1 6 6 6 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain Ank PF00023.30 CEG41403.1 - 0.0085 16.5 4.4 1.3e+02 3.3 0.0 8.1 6 4 0 6 6 6 0 Ankyrin repeat DUF5515 PF17635.2 CEG41403.1 - 0.027 15.2 0.6 22 5.8 0.0 4.6 4 1 1 5 5 5 0 Family of unknown function (DUF5515) DUF5536 PF17688.1 CEG41405.1 - 0.072 13.0 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5536) PLL PF18587.1 CEG41408.1 - 0.017 15.3 0.1 0.02 15.1 0.1 1.1 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain AAA PF00004.29 CEG41409.1 - 3.2e-40 137.6 0.0 8.5e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG41409.1 - 9.6e-08 31.7 0.0 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CEG41409.1 - 4.7e-06 26.8 0.0 1.6e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEG41409.1 - 9.1e-05 22.5 0.1 0.00045 20.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG41409.1 - 0.0011 19.4 0.0 0.0056 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG41409.1 - 0.0012 19.1 0.0 0.0075 16.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CEG41409.1 - 0.0059 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CEG41409.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CEG41409.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG41409.1 - 0.029 13.9 0.0 0.075 12.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEG41409.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEG41409.1 - 0.035 13.8 0.2 0.18 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG41409.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEG41409.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CEG41409.1 - 0.097 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CEG41409.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Citrate_synt PF00285.21 CEG41411.1 - 1.7e-102 343.2 0.0 2.6e-102 342.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CxC6 PF18721.1 CEG41419.1 - 0.042 14.1 0.4 0.042 14.1 0.4 3.2 2 1 1 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Vps16_N PF04841.13 CEG41423.1 - 9.8e-68 228.8 0.0 1.6e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CEG41423.1 - 7.4e-44 150.1 9.1 1.2e-43 149.3 7.1 2.0 2 0 0 2 2 2 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 CEG41423.1 - 0.019 15.2 0.0 0.58 10.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RSN1_7TM PF02714.15 CEG41424.1 - 1.6e-32 113.0 12.6 3.4e-32 111.8 12.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEG41424.1 - 1.6e-09 38.2 0.0 2.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEG41424.1 - 1e-06 28.6 7.0 1.2e-06 28.4 1.1 3.4 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 CEG41424.1 - 4.1 6.1 9.3 8 5.2 4.8 2.8 2 1 0 2 2 2 0 Calcium-activated chloride channel COPIIcoated_ERV PF07970.12 CEG41425.1 - 2.8e-30 105.8 0.2 4.8e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEG41425.1 - 1e-26 93.1 0.2 2.3e-26 92.0 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 CEG41425.1 - 1.7e-20 72.9 0.1 3.9e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG41425.1 - 0.0036 17.7 0.1 0.0084 16.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG41425.1 - 0.0052 17.1 2.5 0.069 13.5 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like Botulinum_HA-17 PF05588.11 CEG41425.1 - 0.13 12.3 3.0 0.067 13.3 0.8 1.6 2 0 0 2 2 2 0 Clostridium botulinum HA-17 domain DZR PF12773.7 CEG41426.1 - 4.8e-24 84.1 51.6 1.3e-09 38.0 7.9 4.2 2 1 2 4 4 4 4 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEG41426.1 - 5.1e-14 51.4 54.5 0.00043 19.9 3.9 6.1 5 1 0 5 5 5 4 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CEG41426.1 - 3e-12 47.1 30.4 0.0023 18.6 0.8 5.6 5 1 0 5 5 5 4 zinc-ribbon family NOB1_Zn_bind PF08772.11 CEG41426.1 - 7.9e-05 22.7 36.1 0.017 15.3 1.6 5.7 5 1 0 5 5 5 5 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 CEG41426.1 - 0.00051 19.4 46.6 0.22 11.0 1.0 6.7 5 2 1 6 6 6 4 zinc-ribbon domain zf-C3HC4_3 PF13920.6 CEG41426.1 - 0.00077 19.3 29.5 0.15 12.0 0.4 5.3 5 0 0 5 5 5 3 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 CEG41426.1 - 0.0059 16.7 8.0 0.0059 16.7 8.0 6.5 6 1 0 7 7 7 3 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.11 CEG41426.1 - 0.018 14.7 0.3 0.018 14.7 0.3 7.1 7 1 0 7 7 7 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 CEG41426.1 - 0.024 14.6 37.5 0.28 11.1 0.3 7.9 8 0 0 8 8 8 0 Nudix N-terminal NAM-associated PF14303.6 CEG41426.1 - 0.042 14.6 0.2 0.042 14.6 0.2 5.0 2 2 2 4 4 3 0 No apical meristem-associated C-terminal domain MqsA_antitoxin PF15731.5 CEG41426.1 - 0.68 10.0 17.4 1.5 8.9 0.2 5.5 5 1 0 6 6 6 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zinc-ribbon_6 PF10005.9 CEG41426.1 - 2.4 8.9 28.1 7.4 7.3 0.3 5.7 5 0 0 5 5 5 0 zinc-ribbon domain HypA PF01155.19 CEG41426.1 - 3.9 7.5 31.8 0.67 10.0 0.6 5.5 5 1 0 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MinC_C PF03775.16 CEG41427.1 - 2.8e-29 101.1 0.1 5.8e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 CEG41427.1 - 0.074 11.6 0.1 0.11 11.0 0.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A 5_nucleotid_C PF02872.18 CEG41429.1 - 5.6e-17 62.4 0.0 1.4e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CEG41429.1 - 1.5e-08 35.4 0.1 3.9e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1345 PF07077.11 CEG41429.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) HTH_Tnp_Tc5 PF03221.16 CEG41430.1 - 2e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2353 PF09789.9 CEG41430.1 - 0.045 13.1 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Kazal_2 PF07648.15 CEG41432.1 - 1.7e-14 53.6 18.3 4.8e-09 36.2 6.3 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG41432.1 - 1.9e-11 43.8 14.9 1.2e-06 28.4 6.0 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Orexin_rec2 PF03827.13 CEG41432.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Orexin receptor type 2 Antifungal_prot PF11402.8 CEG41432.1 - 1 9.7 9.6 0.14 12.5 2.6 2.7 1 1 1 2 2 2 0 Antifungal protein Pkinase PF00069.25 CEG41433.1 - 1.3e-65 221.4 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41433.1 - 5.6e-36 124.2 0.0 2e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FYVE PF01363.21 CEG41433.1 - 3.7e-05 23.8 15.2 8.2e-05 22.7 15.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Methyltransf_PK PF05891.12 CEG41433.1 - 0.034 13.7 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pkinase_fungal PF17667.1 CEG41433.1 - 0.072 11.9 0.1 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FYVE_2 PF02318.16 CEG41433.1 - 0.3 11.3 10.3 0.72 10.1 10.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF382 PF04037.13 CEG41434.1 - 3.6e-58 195.2 0.3 3.6e-58 195.2 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CEG41434.1 - 1.4e-19 69.7 2.4 3.3e-19 68.5 2.4 1.7 1 0 0 1 1 1 1 PSP CSTF_C PF14304.6 CEG41435.1 - 5e-11 42.0 8.1 8.4e-11 41.3 8.1 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 CEG41435.1 - 2.9e-06 27.6 0.8 3.1e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Flu_M1_C PF08289.11 CEG41435.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ste5 PF11610.8 CEG41435.1 - 0.31 11.0 2.6 0.45 10.4 2.6 1.3 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region Sigma70_r4_2 PF08281.12 CEG41435.1 - 0.83 9.4 2.9 5.8 6.7 0.2 2.3 1 1 1 2 2 2 0 Sigma-70, region 4 CAF1 PF04857.20 CEG41436.1 - 6.8e-84 281.7 0.7 1.2e-83 280.9 0.7 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 CEG41436.1 - 0.037 13.7 0.1 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 3'-5' exonuclease DUF2179 PF10035.9 CEG41436.1 - 0.055 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) zf-MYST PF17772.1 CEG41436.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 MYST family zinc finger domain NPL PF17800.1 CEG41437.1 - 1e-08 35.7 0.0 1e-08 35.7 0.0 2.0 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 CEG41437.1 - 0.013 16.0 0.1 0.047 14.2 0.1 2.0 1 1 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain Hid1 PF12722.7 CEG41437.1 - 0.76 7.8 7.1 0.93 7.5 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 CEG41437.1 - 5.4 4.9 7.9 6.5 4.6 7.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Metallophos PF00149.28 CEG41438.1 - 6.6e-22 79.0 0.9 1.2e-21 78.2 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG41438.1 - 7.8e-18 65.1 0.3 3.2e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CEG41438.1 - 4.6e-11 43.1 0.7 1.3e-10 41.7 0.7 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 CEG41438.1 - 0.00051 20.3 0.3 0.022 15.0 0.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1229 PF06797.11 CEG41438.1 - 0.11 12.7 0.2 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1229) DUF5480 PF17576.2 CEG41441.1 - 0.031 14.3 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Thr_synth_N PF14821.6 CEG41441.1 - 0.087 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Threonine synthase N terminus hNIFK_binding PF12196.8 CEG41442.1 - 0.038 13.5 0.2 0.069 12.6 0.2 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK TssR PF17643.1 CEG41444.1 - 0.00096 17.2 0.9 0.0012 16.9 0.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssR Dynactin_p22 PF07426.11 CEG41444.1 - 0.0017 18.3 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 CM_2 PF01817.21 CEG41444.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Chorismate mutase type II NRBF2 PF08961.10 CEG41445.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Poty_PP PF08440.10 CEG41445.1 - 0.041 13.0 0.2 0.08 12.0 0.2 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein DUF5028 PF16431.5 CEG41445.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) Glyco_hydro_3 PF00933.21 CEG41446.1 - 4e-49 167.7 0.0 5.4e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEG41446.1 - 1e-25 90.9 0.0 2.7e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_72 PF03198.14 CEG41448.1 - 9.5e-54 182.8 0.9 1.4e-53 182.2 0.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CEG41448.1 - 0.00027 20.5 0.0 0.0018 17.8 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FMN_red PF03358.15 CEG41450.1 - 1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEG41450.1 - 0.0023 17.7 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DAGK_acc PF00609.19 CEG41451.1 - 2.4e-53 180.7 0.0 4.1e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CEG41451.1 - 7.7e-25 86.9 0.0 1.7e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CEG41451.1 - 3.8e-21 74.7 10.8 3.3e-10 39.7 1.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEG41451.1 - 0.00083 19.6 7.3 0.0061 16.9 0.3 2.7 2 0 0 2 2 2 1 C1 domain PHD PF00628.29 CEG41451.1 - 0.0045 16.9 1.3 0.0045 16.9 1.3 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CEG41451.1 - 0.0045 16.5 11.5 0.48 10.0 0.9 3.7 3 0 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 CEG41451.1 - 0.017 15.2 7.4 0.35 11.0 1.8 2.9 2 1 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 CEG41451.1 - 0.027 14.8 2.2 0.027 14.8 2.2 2.7 2 0 0 2 2 2 0 RING-like domain Zf_RING PF16744.5 CEG41451.1 - 0.32 11.1 9.5 0.65 10.2 0.6 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_9 PF13901.6 CEG41451.1 - 7.9 6.4 12.4 0.86 9.5 0.5 2.8 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon PCRF PF03462.18 CEG41452.1 - 1.3e-47 162.2 0.0 2.5e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CEG41452.1 - 1.4e-37 128.1 0.3 2.6e-37 127.3 0.3 1.4 1 0 0 1 1 1 1 RF-1 domain EF-hand_1 PF00036.32 CEG41456.1 - 1.4e-12 46.2 0.4 2e-06 27.0 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG41456.1 - 2.5e-10 40.7 0.3 1.6e-09 38.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG41456.1 - 2.2e-09 36.5 0.1 0.0013 18.5 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG41456.1 - 7.9e-07 28.3 0.2 0.0053 16.2 0.1 2.5 2 0 0 2 2 2 2 EF hand ALMT PF11744.8 CEG41456.1 - 0.0006 18.8 11.6 0.013 14.4 0.1 2.8 3 0 0 3 3 3 2 Aluminium activated malate transporter EF-hand_8 PF13833.6 CEG41456.1 - 0.0025 17.6 2.2 0.019 14.8 0.3 3.3 3 1 0 3 3 3 1 EF-hand domain pair MCC-bdg_PDZ PF10506.9 CEG41456.1 - 0.1 12.6 0.1 0.32 11.0 0.1 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SPARC_Ca_bdg PF10591.9 CEG41456.1 - 0.14 12.4 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region AIM3 PF17096.5 CEG41457.1 - 0.031 15.2 9.5 0.031 15.2 9.5 5.4 1 1 3 4 4 4 0 Altered inheritance of mitochondria protein 3 DASH_Dad3 PF08656.10 CEG41458.1 - 0.0045 17.1 0.5 0.0061 16.6 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 GAS PF13851.6 CEG41458.1 - 0.013 14.9 0.2 0.014 14.7 0.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PL48 PF15903.5 CEG41458.1 - 0.08 11.9 0.0 0.089 11.7 0.0 1.0 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 SlyX PF04102.12 CEG41458.1 - 0.11 13.1 1.5 0.22 12.2 1.5 1.6 1 1 0 1 1 1 0 SlyX Lyase_1 PF00206.20 CEG41459.1 - 6.3e-114 380.6 0.0 7.8e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CEG41459.1 - 3.6e-24 84.9 0.0 1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus BRAP2 PF07576.12 CEG41464.1 - 0.076 13.2 0.2 0.096 12.9 0.2 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 bPH_1 PF08000.11 CEG41466.1 - 2e-20 73.1 0.2 3.9e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial PH domain bPH_1 PF08000.11 CEG41467.1 - 2.9e-21 75.8 0.3 4.8e-21 75.1 0.3 1.3 1 0 0 1 1 1 1 Bacterial PH domain PhoLip_ATPase_C PF16212.5 CEG41468.1 - 4.2e-75 252.7 24.9 4.2e-75 252.7 24.9 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG41468.1 - 1.1e-19 69.8 1.7 3.2e-19 68.4 1.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG41468.1 - 2.5e-11 44.2 0.0 1.7e-05 25.2 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG41468.1 - 1.1e-09 38.2 0.0 9e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG41468.1 - 6.5e-05 22.5 0.0 0.00019 21.0 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG41468.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TAF1_subA PF14929.6 CEG41476.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Histidinol_dh PF00815.20 CEG41480.1 - 5.3e-128 427.5 4.3 6.5e-128 427.2 4.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Catalase PF00199.19 CEG41481.1 - 5.6e-186 618.2 0.0 8.2e-186 617.7 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEG41481.1 - 1.8e-16 60.1 2.8 3.1e-16 59.3 0.6 2.4 3 0 0 3 3 3 1 Catalase-related immune-responsive DUF4959 PF16323.5 CEG41481.1 - 0.075 13.4 0.2 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) Pkinase PF00069.25 CEG41482.1 - 1.8e-66 224.2 0.0 1.3e-65 221.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41482.1 - 4.5e-28 98.2 0.4 1.5e-26 93.3 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG41482.1 - 0.00048 19.5 2.2 0.0039 16.5 0.1 2.9 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 CEG41482.1 - 0.0049 16.8 0.1 0.035 14.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG41482.1 - 0.021 14.2 0.3 0.043 13.2 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2937 PF11157.8 CEG41482.1 - 0.022 14.5 0.6 0.046 13.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Pkinase PF00069.25 CEG41483.1 - 2.9e-47 161.3 0.0 3.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41483.1 - 2.2e-29 102.6 0.1 2.8e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG41483.1 - 3.7e-05 23.2 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG41483.1 - 0.011 15.7 0.2 0.35 10.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG41483.1 - 0.025 13.9 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEG41483.1 - 0.041 12.7 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Actin PF00022.19 CEG41484.1 - 2.4e-71 240.5 0.1 1.2e-64 218.4 0.0 2.9 2 1 0 2 2 2 2 Actin SF-assemblin PF06705.11 CEG41488.1 - 0.00062 19.2 8.4 0.00062 19.2 8.4 2.9 2 1 0 3 3 3 1 SF-assemblin/beta giardin Glyco_transf_7N PF13733.6 CEG41488.1 - 0.13 11.9 3.1 0.31 10.7 0.6 2.3 1 1 1 2 2 2 0 N-terminal region of glycosyl transferase group 7 Mt_ATP-synt_D PF05873.12 CEG41488.1 - 5.7 6.8 11.3 8 6.3 0.2 3.1 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DNA_topoisoIV PF00521.20 CEG41489.1 - 2.1e-130 435.4 0.1 3.4e-130 434.8 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CEG41489.1 - 6.8e-49 165.4 1.0 1.9e-48 164.0 0.1 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CEG41489.1 - 2.6e-25 88.9 1.3 7.1e-25 87.5 1.3 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CEG41489.1 - 1.7e-11 44.6 0.2 5.3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CEG41489.1 - 1.1e-07 32.0 0.0 8.2e-07 29.2 0.0 2.6 1 0 0 1 1 1 1 Toprim domain EF-hand_1 PF00036.32 CEG41490.1 - 4.9e-12 44.5 2.7 0.0042 16.5 0.1 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG41490.1 - 3.1e-11 43.6 3.2 0.016 15.7 0.2 3.9 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG41490.1 - 1.1e-10 40.6 4.4 0.0018 18.0 0.1 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CEG41490.1 - 2.2e-06 26.9 1.5 0.1 12.1 0.2 4.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEG41490.1 - 0.00013 21.7 2.5 0.12 12.2 0.1 3.8 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEG41490.1 - 0.24 11.7 1.7 67 3.8 0.0 3.7 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.27 CEG41491.1 - 0.022 15.3 0.0 0.073 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CEG41491.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CEG41491.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_9 PF14580.6 CEG41496.1 - 2.1e-11 43.6 1.5 6.1e-07 29.1 0.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CEG41496.1 - 2.1e-09 37.5 2.0 2.6e-05 24.5 0.1 4.2 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG41496.1 - 0.00094 18.9 5.2 0.011 15.4 0.3 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CEG41496.1 - 0.096 12.8 0.1 12 6.3 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich repeat YjeF_N PF03853.15 CEG41497.1 - 4.5e-37 127.6 0.0 5.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus zf-C3HC4_3 PF13920.6 CEG41498.1 - 2.2e-10 40.2 7.5 4.9e-10 39.1 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG41498.1 - 1.4e-08 34.4 8.5 3.2e-08 33.3 8.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UBA PF00627.31 CEG41498.1 - 2.5e-06 27.3 0.0 5.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_5 PF14634.6 CEG41498.1 - 5.8e-06 26.2 8.0 1.5e-05 24.9 8.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG41498.1 - 1.7e-05 25.1 10.1 5.1e-05 23.5 10.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEG41498.1 - 6.3e-05 22.8 10.4 0.00015 21.6 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HATPase_c_3 PF13589.6 CEG41498.1 - 0.00014 21.7 0.0 0.25 11.2 0.0 3.2 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C3HC4_2 PF13923.6 CEG41498.1 - 0.00038 20.2 9.8 0.00096 18.9 9.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41498.1 - 0.00048 20.1 4.1 0.00048 20.1 4.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger TTKRSYEDQ PF10212.9 CEG41498.1 - 0.02 13.9 0.3 0.048 12.6 0.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein zf-C3HC4_4 PF15227.6 CEG41498.1 - 1.2 9.4 13.1 0.75 10.0 10.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RXT2_N PF08595.11 CEG41498.1 - 1.3 9.0 4.1 4.3 7.4 4.1 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-RING_6 PF14835.6 CEG41498.1 - 1.4 8.8 4.5 4.5 7.2 4.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEG41498.1 - 2.3 8.6 4.6 6.2 7.2 4.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG41498.1 - 3 7.7 5.5 12 5.7 5.5 2.2 1 0 0 1 1 1 0 RING-like zinc finger HAT_KAT11 PF08214.11 CEG41499.1 - 3.6e-25 89.0 1.9 4.4e-25 88.7 0.7 1.7 1 1 1 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 CEG41499.1 - 6.5e-12 45.3 0.9 2.2e-11 43.7 0.0 2.4 3 0 0 3 3 3 1 Bromodomain PHD PF00628.29 CEG41499.1 - 5.7e-05 22.9 4.2 5.7e-05 22.9 4.2 4.5 4 1 0 4 4 4 1 PHD-finger DUF902 PF06001.13 CEG41499.1 - 0.69 10.4 8.2 0.83 10.2 1.9 2.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) DUF3402 PF11882.8 CEG41500.1 - 3.6e-30 105.5 4.3 2.8e-21 76.2 0.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CEG41500.1 - 2e-08 33.8 0.5 4.2e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 N1221-like protein Proteasome PF00227.26 CEG41501.1 - 1.3e-39 135.7 0.3 2.7e-37 128.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 CEG41501.1 - 1.3e-12 47.1 0.0 2.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature OTU PF02338.19 CEG41502.1 - 1.1e-15 58.2 0.4 3.9e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Ank_4 PF13637.6 CEG41502.1 - 2.7e-13 50.1 0.9 4.3e-07 30.3 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG41502.1 - 1.7e-09 37.7 0.6 7.1e-07 29.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41502.1 - 2.4e-09 37.7 0.1 6.1e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEG41502.1 - 1.5e-08 34.7 0.2 0.0024 18.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG41502.1 - 4.9e-08 32.6 0.1 0.011 16.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat MBT PF02820.18 CEG41502.1 - 0.00077 19.8 0.0 0.47 10.9 0.0 2.4 2 0 0 2 2 2 2 mbt repeat UIM PF02809.20 CEG41502.1 - 0.015 15.2 19.7 0.48 10.5 0.2 5.6 5 0 0 5 5 5 0 Ubiquitin interaction motif Peptidase_C65 PF10275.9 CEG41502.1 - 0.61 9.5 4.6 5.7 6.3 0.1 2.9 2 1 1 3 3 3 0 Peptidase C65 Otubain Peptidase_S9 PF00326.21 CEG41503.1 - 2.6e-50 170.9 0.0 3.5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CEG41503.1 - 7.9e-13 48.6 2.2 1e-11 44.9 0.4 2.3 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CEG41503.1 - 9.9e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CEG41503.1 - 0.0056 16.0 0.3 0.038 13.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CEG41503.1 - 0.0084 15.8 0.0 0.039 13.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CEG41503.1 - 0.056 13.0 0.4 0.64 9.5 0.4 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family F-box PF00646.33 CEG41504.1 - 0.24 11.3 4.2 0.14 12.0 1.1 2.3 2 0 0 2 2 2 0 F-box domain Bromodomain PF00439.25 CEG41506.1 - 2.3e-38 130.1 0.1 5.9e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain WSD PF15613.6 CEG41506.1 - 1e-13 51.5 0.2 1.8e-12 47.5 0.2 2.9 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DNMT1-RFD PF12047.8 CEG41506.1 - 1.3e-07 31.7 0.1 1.2e-05 25.4 0.0 3.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain WHIM1 PF15612.6 CEG41506.1 - 0.0027 17.2 0.3 0.0097 15.4 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 CEG41506.1 - 0.0029 17.9 0.4 0.0063 16.8 0.4 1.6 1 0 0 1 1 1 1 DDT domain Auxin_resp PF06507.13 CEG41506.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Auxin response factor PX PF00787.24 CEG41507.1 - 2.8e-11 43.4 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 PX domain DPPIV_N PF00930.21 CEG41508.1 - 4.2e-51 173.8 0.0 7.7e-49 166.3 0.0 2.9 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 CEG41508.1 - 2.1e-07 30.7 3.2 0.04 13.9 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 CEG41508.1 - 0.023 14.4 1.3 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.32 CEG41508.1 - 0.1 13.5 1.1 21 6.2 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat TruB_C PF09142.11 CEG41508.1 - 0.15 11.9 0.0 24 4.8 0.0 2.6 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal PAD_M PF08527.10 CEG41509.1 - 0.0015 18.3 1.0 0.0022 17.7 1.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain ALMT PF11744.8 CEG41509.1 - 0.45 9.3 6.8 0.61 8.8 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1729 PF08354.10 CEG41510.1 - 4.9e-132 440.1 0.0 8.6e-132 439.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 CEG41510.1 - 2.7e-92 307.4 0.1 8.1e-45 153.1 0.1 2.9 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 CEG41510.1 - 3.5e-52 177.9 0.1 3e-50 171.5 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 CEG41510.1 - 5.3e-35 120.9 0.8 1.1e-21 77.4 1.1 2.6 1 1 0 2 2 2 2 Fatty acid synthase type I helical domain SAT PF16073.5 CEG41510.1 - 2.7e-30 105.9 0.2 6.5e-30 104.6 0.2 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 CEG41510.1 - 6.3e-19 67.7 0.0 2.1e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 CEG41510.1 - 1.1e-16 61.0 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain ketoacyl-synt PF00109.26 CEG41510.1 - 1.4e-16 60.9 0.1 3.9e-16 59.4 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CEG41510.1 - 2e-15 56.9 0.1 1.1e-14 54.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 CEG41510.1 - 1.4e-13 50.9 0.0 3.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 CEG41510.1 - 3.1e-08 33.3 0.0 8.8e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG41510.1 - 7.6e-06 25.7 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C3HC4_3 PF13920.6 CEG41511.1 - 4.8e-13 48.8 10.0 9.6e-13 47.8 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 CEG41511.1 - 4.5e-10 40.0 1.5 9.6e-08 32.5 1.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG41511.1 - 2.2e-09 37.4 2.3 4.7e-07 30.0 0.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG41511.1 - 6.2e-09 35.9 3.8 0.002 18.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CEG41511.1 - 8.6e-09 35.8 0.6 3.9e-07 30.5 0.5 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH PF00169.29 CEG41511.1 - 3.5e-08 33.9 0.3 6.1e-08 33.1 0.3 1.4 1 0 0 1 1 1 1 PH domain Prok-RING_4 PF14447.6 CEG41511.1 - 2.9e-07 30.2 10.6 6.2e-07 29.2 10.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank_3 PF13606.6 CEG41511.1 - 4.8e-06 26.5 0.4 0.34 11.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 CEG41511.1 - 1.5e-05 25.2 10.8 3.2e-05 24.2 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain PH_11 PF15413.6 CEG41511.1 - 1.5e-05 25.3 0.3 3.2e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C3HC4_2 PF13923.6 CEG41511.1 - 0.0001 22.1 10.8 0.00019 21.2 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG41511.1 - 0.01 15.7 9.5 0.01 15.7 9.5 1.8 2 0 0 2 2 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEG41511.1 - 0.068 13.3 10.7 0.15 12.3 10.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEG41511.1 - 0.56 10.5 5.9 1.2 9.5 5.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEG41511.1 - 0.66 10.0 6.8 0.21 11.7 3.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 CEG41511.1 - 1.7 8.5 9.1 3.8 7.4 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 CEG41512.1 - 8.6e-11 42.3 0.9 0.00013 22.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEG41512.1 - 3.5e-09 36.7 0.0 0.0011 19.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEG41512.1 - 2.2e-06 27.8 1.6 1.3e-05 25.3 0.6 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG41512.1 - 3.9e-06 27.3 0.5 0.00036 21.0 0.1 3.5 1 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG41512.1 - 6.1e-05 23.1 0.1 0.2 12.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat W2 PF02020.18 CEG41513.1 - 1.9e-16 60.0 3.5 1e-15 57.6 3.2 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 CEG41513.1 - 4.1e-10 39.7 0.0 7.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEG41513.1 - 1.5e-05 24.5 20.1 0.033 13.9 4.3 4.7 2 1 3 6 6 6 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEG41513.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 CEG41513.1 - 0.014 13.6 5.6 0.015 13.4 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 CEG41513.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 CEG41513.1 - 0.029 13.3 0.9 0.06 12.3 0.3 1.8 2 0 0 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 CEG41513.1 - 0.76 9.6 13.9 49 3.8 10.5 3.5 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.26 CEG41515.1 - 4.2e-31 108.0 0.0 5.4e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEG41515.1 - 1.1e-12 48.4 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CEG41515.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEG41515.1 - 0.0069 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 CEG41515.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Bep_C_terminal PF17841.1 CEG41516.1 - 0.053 13.7 2.5 0.13 12.5 0.1 2.3 1 1 1 2 2 2 0 BID domain of Bartonella effector protein (Bep) YvrJ PF12841.7 CEG41517.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family PEP-utilisers_N PF05524.13 CEG41518.1 - 0.032 14.4 0.3 0.061 13.5 0.2 1.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal pPIWI_RE_X PF13111.6 CEG41518.1 - 0.058 12.6 0.0 0.077 12.2 0.0 1.3 1 1 0 1 1 1 0 pPIWI_RE module N-terminal domain CRAL_TRIO PF00650.20 CEG41519.1 - 7.7e-35 120.0 0.0 1.2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG41519.1 - 0.0077 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PB1 PF00564.24 CEG41520.1 - 4.9e-07 29.6 0.0 1.9e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 PB1 domain CUE PF02845.16 CEG41520.1 - 0.00015 21.4 0.1 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 CUE domain UPF0181 PF03701.14 CEG41520.1 - 0.023 14.3 1.0 0.045 13.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Syntaxin_2 PF14523.6 CEG41520.1 - 0.051 13.9 1.5 0.12 12.8 1.1 1.8 1 1 1 2 2 2 0 Syntaxin-like protein IL12 PF03039.14 CEG41520.1 - 0.17 11.2 1.9 6.4 6.0 0.1 2.6 2 1 1 3 3 3 0 Interleukin-12 alpha subunit DUF948 PF06103.11 CEG41520.1 - 2.3 8.5 6.2 34 4.8 0.2 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Stk19 PF10494.9 CEG41521.1 - 3.3e-28 99.0 0.1 4.9e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 RE_Eco29kI PF09517.10 CEG41521.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Eco29kI restriction endonuclease UFD1 PF03152.14 CEG41522.1 - 8e-73 243.6 0.0 1.1e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 EF-1_beta_acid PF10587.9 CEG41522.1 - 0.2 12.2 0.8 0.47 10.9 0.8 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region HasA PF06438.12 CEG41525.1 - 0.0057 16.3 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 Heme-binding protein A (HasA) gag-asp_proteas PF13975.6 CEG41525.1 - 0.007 16.9 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UPF0113 PF03657.13 CEG41525.1 - 0.045 14.0 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain Bunya_NS-S_2 PF03231.13 CEG41528.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-S zf-RING_2 PF13639.6 CEG41529.1 - 6.2e-07 29.7 21.8 0.00018 21.8 17.9 2.9 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG41529.1 - 1.9e-05 24.9 16.5 2.1e-05 24.7 13.6 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG41529.1 - 2.8e-05 23.9 7.7 2.8e-05 23.9 7.7 3.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG41529.1 - 0.00015 21.4 9.6 0.00063 19.4 2.1 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 CEG41529.1 - 0.00049 20.0 11.8 0.12 12.3 11.8 2.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG41529.1 - 0.00095 19.0 6.4 0.00095 19.0 6.4 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41529.1 - 0.0018 18.2 8.9 0.049 13.7 8.9 2.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CEG41529.1 - 0.0083 16.2 5.1 0.0083 16.2 5.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CEG41529.1 - 0.0087 15.9 15.7 0.25 11.2 15.7 2.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG41529.1 - 2 8.1 14.6 0.44 10.2 10.3 2.2 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CEG41529.1 - 7.1 6.9 13.5 1.2 9.3 1.6 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain Pex26 PF07163.12 CEG41530.1 - 0.29 10.4 5.3 2.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Pex26 protein FYVE PF01363.21 CEG41531.1 - 4.3e-12 46.0 10.2 8.3e-12 45.1 10.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG41531.1 - 0.0082 16.3 4.1 0.034 14.3 4.1 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 CEG41531.1 - 0.027 14.8 8.8 0.051 13.9 6.0 2.5 2 0 0 2 2 2 0 C1 domain zf-RING_5 PF14634.6 CEG41531.1 - 0.56 10.2 10.9 1.1 9.3 10.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain HBS1_N PF08938.10 CEG41531.1 - 0.66 10.3 4.0 0.25 11.7 0.9 1.8 2 0 0 2 2 2 0 HBS1 N-terminus DUF2489 PF10675.9 CEG41531.1 - 0.83 9.6 4.4 1 9.3 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) zf-HIT PF04438.16 CEG41531.1 - 2.3 8.2 11.1 0.69 9.8 6.5 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-RING_2 PF13639.6 CEG41531.1 - 3.7 8.0 13.4 2.5 8.5 11.2 2.0 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.22 CEG41531.1 - 3.8 7.5 9.2 0.31 11.0 4.5 1.6 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 CEG41531.1 - 8.5 6.6 10.7 0.99 9.6 6.1 1.8 1 1 0 1 1 1 0 B-box zinc finger Siva PF05458.12 CEG41531.1 - 9 5.9 8.9 19 4.9 8.6 1.6 1 1 0 1 1 1 0 Cd27 binding protein (Siva) dsDNA_bind PF01984.20 CEG41532.1 - 1.2e-26 93.2 15.6 1.3e-26 93.0 15.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.27 CEG41532.1 - 0.00029 21.3 1.8 0.00044 20.7 1.8 1.3 1 0 0 1 1 1 1 PCI domain TetR_C_11 PF16859.5 CEG41532.1 - 0.018 15.3 1.6 0.026 14.9 1.6 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PaaX PF07848.12 CEG41532.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.7 1 1 1 2 2 2 0 PaaX-like protein GcpE PF04551.14 CEG41532.1 - 0.5 9.4 3.0 0.6 9.1 3.0 1.1 1 0 0 1 1 1 0 GcpE protein PP2C PF00481.21 CEG41533.1 - 3.4e-33 115.4 0.1 6.6e-33 114.4 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG41533.1 - 1.2e-08 34.9 0.1 6.4e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Med4 PF10018.9 CEG41534.1 - 2.3e-22 79.6 0.7 2.3e-22 79.6 0.7 1.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 eIF3_N PF09440.10 CEG41534.1 - 0.83 10.1 5.0 2.1 8.8 5.0 1.7 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain PigN PF04987.14 CEG41535.1 - 1.4e-121 406.5 40.1 2.1e-121 406.0 40.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CEG41535.1 - 3.2e-09 36.8 0.3 8.7e-05 22.3 0.2 2.3 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CEG41535.1 - 8.8e-06 25.3 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF5493 PF17597.2 CEG41535.1 - 0.026 14.8 3.2 0.048 13.9 0.1 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Tmemb_18A PF09771.9 CEG41535.1 - 0.36 11.2 3.0 0.37 11.2 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 188 Planc_extracel PF07595.12 CEG41536.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Planctomycete extracellular ASRT PF07100.11 CEG41537.1 - 0.041 13.9 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer MFS_1 PF07690.16 CEG41540.1 - 2.2e-18 66.3 58.9 5.4e-18 65.0 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG41540.1 - 2e-08 33.5 7.6 2e-08 33.5 7.6 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG41541.1 - 3e-18 65.9 36.2 3e-18 65.9 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG41541.1 - 3.3e-12 46.0 6.1 3.3e-12 46.0 6.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2678 PF10856.8 CEG41541.1 - 0.034 14.1 4.6 0.28 11.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) OTU PF02338.19 CEG41542.1 - 2e-07 31.5 0.0 3.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C54 PF03416.19 CEG41544.1 - 5.5e-90 301.5 0.0 6.6e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 CEG41544.1 - 0.12 11.8 0.5 0.37 10.2 0.2 1.8 2 0 0 2 2 2 0 Peptidase family C78 MRF_C1 PF13887.6 CEG41545.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Proteasome PF00227.26 CEG41550.1 - 3.3e-58 196.3 0.0 3.9e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Myotub-related PF06602.14 CEG41551.1 - 3.9e-146 486.5 0.5 6.2e-146 485.8 0.5 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 CEG41551.1 - 1.6e-19 69.8 9.2 3.3e-19 68.8 8.2 2.1 2 0 0 2 2 2 1 FYVE zinc finger Rhomboid PF01694.22 CEG41551.1 - 2.9e-17 63.0 12.5 1.7e-12 47.6 2.1 2.3 2 0 0 2 2 2 2 Rhomboid family DSPc PF00782.20 CEG41551.1 - 1.8e-05 24.5 0.1 5.6e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG41551.1 - 0.00012 21.8 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GRAM PF02893.20 CEG41551.1 - 0.00077 19.3 0.2 0.011 15.6 0.2 2.8 1 1 0 1 1 1 1 GRAM domain 3-PAP PF12578.8 CEG41551.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-associated protein Y_phosphatase3 PF13350.6 CEG41551.1 - 0.0028 17.7 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family GATA PF00320.27 CEG41551.1 - 3.6 7.3 6.0 11 5.8 1.5 3.2 2 1 1 3 3 3 0 GATA zinc finger FYVE_2 PF02318.16 CEG41551.1 - 7.8 6.7 12.5 0.49 10.6 5.3 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Glyco_transf_20 PF00982.21 CEG41552.1 - 2.5e-176 587.0 0.0 3.3e-176 586.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG41552.1 - 2.9e-39 134.6 0.0 8.1e-39 133.1 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase FlxA PF14282.6 CEG41552.1 - 0.02 14.9 1.5 0.02 14.9 1.5 1.9 2 0 0 2 2 2 0 FlxA-like protein SPRY PF00622.28 CEG41553.1 - 2.6e-18 66.3 0.0 5.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 CEG41553.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Neuralized LRR_4 PF12799.7 CEG41554.1 - 4.5e-20 71.4 24.1 0.013 15.9 0.1 10.5 4 2 6 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG41554.1 - 1.9e-18 66.0 16.0 6e-07 29.1 1.4 7.8 6 2 3 9 9 9 7 Leucine rich repeat LRR_6 PF13516.6 CEG41554.1 - 1.5e-16 58.9 31.4 0.038 14.0 0.1 12.5 13 0 0 13 13 13 6 Leucine Rich repeat LRR_1 PF00560.33 CEG41554.1 - 0.00021 21.4 19.9 65 4.7 0.0 11.0 11 2 0 11 11 11 0 Leucine Rich Repeat LRR_9 PF14580.6 CEG41554.1 - 0.01 15.4 10.1 0.074 12.6 0.3 4.2 3 1 2 5 5 5 0 Leucine-rich repeat DREV PF05219.12 CEG41554.1 - 0.05 12.7 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 DREV methyltransferase SlyX PF04102.12 CEG41555.1 - 0.048 14.3 0.1 0.048 14.3 0.1 6.2 4 3 1 6 6 6 0 SlyX FAD_binding_6 PF00970.24 CEG41556.1 - 3.4e-35 120.4 0.0 6.4e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CEG41556.1 - 3.9e-33 114.3 0.0 6.9e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEG41556.1 - 0.00025 21.2 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEG41556.1 - 0.0039 17.4 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_synthase PF02540.17 CEG41557.1 - 2.4e-07 30.1 0.0 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 CEG41557.1 - 2.2e-06 27.6 0.0 3.5e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 CEG41557.1 - 8.2e-06 24.8 0.0 0.0057 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 CEG41557.1 - 8.3e-06 25.4 0.6 0.032 13.7 0.0 3.0 2 2 1 3 3 3 2 Queuosine biosynthesis protein QueC TAF PF02969.17 CEG41557.1 - 0.05 13.8 0.0 11 6.3 0.0 2.7 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) ATP_bind_3 PF01171.20 CEG41557.1 - 0.071 12.9 1.5 0.24 11.1 0.2 2.5 2 1 0 2 2 2 0 PP-loop family PAP_central PF04928.17 CEG41557.1 - 0.087 11.8 0.0 0.23 10.4 0.0 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain PAPS_reduct PF01507.19 CEG41557.1 - 0.15 12.1 0.1 0.35 10.9 0.0 1.7 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 CEG41558.1 - 7.2e-20 71.0 1.6 6.2e-07 30.0 0.4 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41558.1 - 6.9e-11 42.3 0.1 0.017 15.4 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG41558.1 - 6.7e-05 21.7 0.4 1.5 7.4 0.0 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CEG41558.1 - 0.042 12.8 0.1 0.1 11.5 0.1 1.6 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Pertussis_S2S3 PF02918.15 CEG41559.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Pertussis toxin, subunit 2 and 3, C-terminal domain CcmH PF03918.14 CEG41559.1 - 0.056 12.7 0.2 0.26 10.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein HAGH_C PF16123.5 CEG41560.1 - 2.6e-25 88.7 0.1 7.4e-25 87.3 0.0 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEG41560.1 - 6.6e-10 39.3 3.6 2.7e-09 37.3 2.7 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEG41560.1 - 0.0031 17.1 0.9 0.0069 15.9 0.4 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEG41560.1 - 0.015 15.2 0.2 0.029 14.3 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosom_S12_S23 PF00164.25 CEG41561.1 - 5.2e-49 164.6 0.7 6.7e-49 164.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peroxidase_2 PF01328.17 CEG41562.1 - 1.3e-15 58.4 0.0 2e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 PWI PF01480.17 CEG41562.1 - 3e-08 33.9 0.1 9.6e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 CEG41562.1 - 0.022 14.6 0.4 0.063 13.1 0.2 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_trans_3N PF02885.17 CEG41562.1 - 0.072 12.9 0.3 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain DUF1609 PF07753.11 CEG41565.1 - 0.031 13.8 0.1 0.035 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Phage_Nu1 PF07471.12 CEG41565.1 - 0.082 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF2228 PF10228.9 CEG41568.1 - 8.1e-62 209.2 0.0 9.7e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Spermine_synth PF01564.17 CEG41569.1 - 7.9e-43 146.1 0.0 1.2e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CEG41569.1 - 3.8e-10 39.5 0.2 8.1e-10 38.4 0.2 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CEG41569.1 - 0.0046 17.6 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 CEG41569.1 - 0.019 14.8 0.0 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase DUF43 PF01861.16 CEG41569.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Glyco_hydro_36N PF16875.5 CEG41569.1 - 0.18 11.4 0.0 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 N-terminal domain EF_TS PF00889.19 CEG41570.1 - 1.4e-51 175.1 0.1 1.8e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor TS Val_tRNA-synt_C PF10458.9 CEG41570.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm HTH_34 PF13601.6 CEG41570.1 - 0.064 13.4 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain APH PF01636.23 CEG41571.1 - 3.4e-39 135.2 0.1 5.4e-39 134.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 CEG41571.1 - 9.7e-35 120.0 4.1 1.6e-34 119.3 4.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEG41571.1 - 4.8e-16 58.7 0.0 1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG41571.1 - 2.3e-11 44.1 1.6 2.3e-11 44.1 1.6 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG41571.1 - 2.8e-08 34.4 0.0 7.8e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain EcKinase PF02958.20 CEG41571.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 CEG41571.1 - 0.00019 21.1 0.0 0.063 12.9 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 CEG41571.1 - 0.0066 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.14 CEG41571.1 - 0.1 11.9 0.0 0.99 8.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CEG41571.1 - 0.16 11.1 0.0 0.58 9.3 0.0 1.9 1 1 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 CEG41572.1 - 2.7e-62 210.5 0.0 4.4e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Acyl-CoA_dh_1 PF00441.24 CEG41572.1 - 9e-49 165.5 3.0 2.2e-48 164.3 3.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG41572.1 - 6.2e-34 117.1 0.0 1.5e-33 115.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pkinase_Tyr PF07714.17 CEG41572.1 - 1.7e-27 96.3 0.0 2.8e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_M PF02770.19 CEG41572.1 - 4.6e-27 94.1 0.0 1.1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG41572.1 - 1e-22 80.8 1.9 3.4e-22 79.1 1.9 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RGS PF00615.19 CEG41572.1 - 1.1e-10 41.8 1.2 1.3e-06 28.6 0.2 2.8 3 0 0 3 3 3 2 Regulator of G protein signaling domain HpaB_N PF11794.8 CEG41572.1 - 3.1e-05 23.8 0.0 8.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Kinase-like PF14531.6 CEG41572.1 - 0.00051 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG41572.1 - 0.015 14.3 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG41572.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAPKK1_Int PF08923.10 CEG41576.1 - 2e-19 69.5 0.0 2.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting EXS PF03124.14 CEG41577.1 - 8.3e-64 216.0 17.1 1e-63 215.7 17.1 1.0 1 0 0 1 1 1 1 EXS family Ipi1_N PF12333.8 CEG41577.1 - 0.089 13.4 0.1 0.21 12.2 0.1 1.7 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Inositol_P PF00459.25 CEG41578.1 - 1.4e-64 218.3 0.3 1.6e-64 218.1 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 CEG41578.1 - 0.012 14.5 0.1 0.027 13.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Cytochrom_NNT PF03264.14 CEG41581.1 - 0.018 14.7 1.1 0.042 13.6 1.1 1.5 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF1192 PF06698.11 CEG41581.1 - 0.019 15.0 2.1 0.15 12.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Tim17 PF02466.19 CEG41582.1 - 4.8e-14 52.7 8.5 6.1e-14 52.3 8.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Band_7 PF01145.25 CEG41583.1 - 5.8e-22 78.6 1.6 5.8e-22 78.6 1.6 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family S4 PF01479.25 CEG41584.1 - 4.9e-09 35.8 0.5 4.9e-09 35.8 0.5 2.3 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 CEG41584.1 - 6.7e-06 26.9 3.0 2.2e-05 25.3 3.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Clathrin PF00637.20 CEG41585.1 - 8.1e-16 58.2 3.3 8.1e-16 58.2 3.3 3.1 2 1 1 3 3 3 1 Region in Clathrin and VPS Aminotran_5 PF00266.19 CEG41585.1 - 1.6e-06 27.4 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 CEG41585.1 - 0.00039 21.2 0.1 0.0014 19.4 0.1 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Vps39_2 PF10367.9 CEG41585.1 - 0.0028 18.1 0.6 0.02 15.3 0.3 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CEG41585.1 - 0.0096 15.9 4.5 0.025 14.6 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_1 PF10366.9 CEG41585.1 - 0.022 15.0 0.9 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.6 CEG41585.1 - 0.028 14.8 8.2 0.08 13.3 8.2 1.9 1 0 0 1 1 1 0 Ring finger domain DUF1272 PF06906.11 CEG41585.1 - 0.094 12.8 2.8 0.27 11.3 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 CEG41585.1 - 0.24 11.7 3.8 0.69 10.2 3.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG41585.1 - 0.88 9.4 7.5 3 7.6 7.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CEG41585.1 - 0.9 9.6 8.5 2.3 8.2 8.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF4203 PF13886.6 CEG41587.1 - 1.1e-32 113.4 32.8 1.5e-32 112.9 32.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) VIT1 PF01988.19 CEG41587.1 - 2 8.2 0.0 2 8.2 0.0 2.9 2 1 1 3 3 3 0 VIT family Fe-ADH PF00465.19 CEG41588.1 - 8.9e-54 182.7 2.2 1.2e-53 182.3 2.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CEG41588.1 - 9e-07 28.8 1.4 0.0002 21.2 0.1 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase adh_short PF00106.25 CEG41589.1 - 1.4e-30 106.3 0.0 9.3e-30 103.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG41589.1 - 1.9e-19 70.2 0.0 3.1e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG41589.1 - 7.7e-09 35.7 0.1 1.2e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG41589.1 - 3.9e-05 23.2 0.5 0.00011 21.8 0.2 1.7 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 CEG41589.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_54 PF04666.13 CEG41589.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region WD40 PF00400.32 CEG41590.1 - 2e-30 104.4 8.6 8.8e-06 26.4 0.0 5.7 5 1 1 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 CEG41590.1 - 1.2e-22 80.0 17.5 2.2e-22 79.1 17.5 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CEG41590.1 - 2.5e-08 34.1 0.0 0.0046 17.2 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG41590.1 - 8e-07 29.1 0.1 0.00014 21.8 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A UPF0147 PF03685.13 CEG41590.1 - 0.038 14.0 1.3 0.11 12.6 1.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Ge1_WD40 PF16529.5 CEG41590.1 - 0.073 12.0 0.0 0.43 9.5 0.0 2.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_8 PF13181.6 CEG41593.1 - 4.4e-15 54.6 0.1 0.00017 21.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG41593.1 - 1.8e-14 52.6 0.1 0.0016 18.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat FYVE PF01363.21 CEG41593.1 - 1e-13 51.2 9.1 1.8e-13 50.4 9.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_1 PF00515.28 CEG41593.1 - 1.8e-11 43.3 0.0 0.026 14.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG41593.1 - 3.9e-10 39.7 4.1 0.00086 19.9 0.0 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEG41593.1 - 4.9e-10 39.0 0.1 0.0077 16.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG41593.1 - 1.7e-09 37.8 0.1 0.00047 20.4 0.4 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG41593.1 - 7.8e-09 35.0 0.4 0.028 14.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG41593.1 - 1.5e-08 34.1 0.0 0.0031 17.1 0.0 2.7 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 CEG41593.1 - 7.1e-08 33.0 1.9 3.3e-05 24.4 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.7 CEG41593.1 - 7.6e-07 29.6 0.0 2.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_17 PF13431.6 CEG41593.1 - 1.9e-06 27.9 0.1 0.17 12.3 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG41593.1 - 2.4e-06 27.9 0.0 0.00051 20.5 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat Ank_5 PF13857.6 CEG41593.1 - 1.2e-05 25.5 0.2 0.0021 18.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) ANAPC3 PF12895.7 CEG41593.1 - 4.3e-05 23.7 0.0 0.011 15.9 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CEG41593.1 - 0.00017 21.9 0.0 12 6.9 0.2 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Ank_3 PF13606.6 CEG41593.1 - 0.00026 21.2 0.0 1.4 9.7 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CEG41593.1 - 0.0028 18.2 0.2 0.023 15.3 0.0 2.7 2 1 1 3 3 2 1 Ankyrin repeats (many copies) TPR_15 PF13429.6 CEG41593.1 - 0.0052 16.0 0.1 0.23 10.7 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Ank PF00023.30 CEG41593.1 - 0.026 15.0 0.5 10 6.8 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat TPR_20 PF14561.6 CEG41593.1 - 0.026 14.9 0.0 0.25 11.7 0.0 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat HAUS-augmin3 PF14932.6 CEG41593.1 - 0.029 14.0 0.5 0.052 13.1 0.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 CEG41593.1 - 0.03 13.9 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MalT PF17874.1 CEG41593.1 - 0.037 13.4 0.0 0.67 9.3 0.0 2.3 1 1 1 2 2 2 0 MalT-like TPR region SHNi-TPR PF10516.9 CEG41593.1 - 0.058 12.9 3.5 0.073 12.5 0.1 2.6 3 0 0 3 3 3 0 SHNi-TPR HalX PF08663.10 CEG41593.1 - 0.69 10.3 7.1 8.5 6.8 0.3 2.6 2 0 0 2 2 2 0 HalX domain Tnp_zf-ribbon_2 PF13842.6 CEG41593.1 - 4.2 8.3 7.0 9.8 7.1 7.0 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon MORN PF02493.20 CEG41594.1 - 1e-13 50.3 12.8 2.1e-05 24.1 0.9 3.7 4 0 0 4 4 4 3 MORN repeat VHS PF00790.19 CEG41595.1 - 7.7e-28 97.1 0.0 1.5e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CEG41595.1 - 0.00026 21.2 0.8 0.0024 18.1 0.3 2.5 1 1 1 2 2 2 1 GAT domain ENTH PF01417.20 CEG41595.1 - 0.0025 17.8 0.0 0.027 14.5 0.0 2.3 3 0 0 3 3 3 1 ENTH domain GUN4_N PF16416.5 CEG41595.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.3 4 0 0 4 4 4 0 ARM-like repeat domain, GUN4-N terminal DUF2015 PF09435.10 CEG41596.1 - 0.088 12.7 0.0 0.099 12.5 0.0 1.0 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) zf-CGNR PF11706.8 CEG41598.1 - 4.7 7.1 15.5 4.1 7.3 0.7 3.5 2 1 1 3 3 3 0 CGNR zinc finger DUF563 PF04577.14 CEG41599.1 - 8.7e-25 88.1 0.0 2.9e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF563 PF04577.14 CEG41601.1 - 4.4e-27 95.6 0.1 8.4e-27 94.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Carbpep_Y_N PF05388.11 CEG41601.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Hydrolase_4 PF12146.8 CEG41605.1 - 1.9e-06 27.3 0.0 0.0038 16.5 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 AAA_29 PF13555.6 CEG41605.1 - 0.033 13.9 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GCP_N_terminal PF17681.1 CEG41605.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Abhydrolase_1 PF00561.20 CEG41605.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Npa1 PF11707.8 CEG41606.1 - 2.5e-23 83.0 3.2 2.5e-23 83.0 3.2 3.1 2 1 1 3 3 3 1 Ribosome 60S biogenesis N-terminal dsDNA_bind PF01984.20 CEG41606.1 - 0.054 13.8 0.1 2.8 8.3 0.1 2.9 2 0 0 2 2 2 0 Double-stranded DNA-binding domain His_Phos_2 PF00328.22 CEG41608.1 - 6e-23 81.8 0.9 1.7e-22 80.3 0.9 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2228 PF10228.9 CEG41608.1 - 0.058 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) LRR_4 PF12799.7 CEG41609.1 - 6.9e-20 70.8 6.6 7.4e-06 26.2 0.1 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG41609.1 - 2.9e-17 62.7 3.6 1.1e-15 57.5 3.3 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 CEG41609.1 - 7.4e-13 48.0 27.2 3.1e-06 26.8 0.4 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 CEG41609.1 - 0.033 14.2 5.4 12 6.2 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat SAM_3 PF18016.1 CEG41609.1 - 0.38 10.6 2.3 3.4 7.5 0.2 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 CEG41609.1 - 1.8 9.5 8.2 4.1e+02 2.2 0.0 5.6 4 1 1 5 5 5 0 Leucine Rich Repeat F_bP_aldolase PF01116.20 CEG41610.1 - 2.8e-91 305.9 0.1 3.2e-91 305.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II GCIP PF13324.6 CEG41611.1 - 9.9e-25 87.6 1.9 1.4e-24 87.1 1.9 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting zf-C3HC4 PF00097.25 CEG41612.1 - 2.9e-08 33.5 10.1 2.9e-08 33.5 10.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG41612.1 - 2.2e-07 30.9 11.8 2.2e-07 30.9 11.8 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CEG41612.1 - 9.2e-07 28.8 10.6 2.3e-06 27.5 10.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEG41612.1 - 1e-06 28.4 11.3 1e-06 28.4 11.3 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEG41612.1 - 1.9e-05 24.4 5.1 1.9e-05 24.4 5.1 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CEG41612.1 - 2.5e-05 24.1 13.5 2.5e-05 24.1 13.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41612.1 - 5.9e-05 23.3 11.5 5.9e-05 23.3 11.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CEG41612.1 - 0.00016 21.6 13.4 0.00016 21.6 13.4 2.4 2 0 0 2 2 1 1 zinc-RING finger domain U-box PF04564.15 CEG41612.1 - 0.002 18.3 0.0 0.0085 16.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 CEG41612.1 - 0.025 14.6 13.5 0.17 11.9 8.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEG41612.1 - 0.087 12.7 14.7 0.25 11.2 14.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG41612.1 - 9.7 6.6 18.4 1.9 8.8 10.4 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain RRS1 PF04939.12 CEG41616.1 - 3.5e-52 176.5 6.3 3.5e-52 176.5 6.3 2.3 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) SelK_SelG PF10961.8 CEG41617.1 - 5.5e-21 75.0 1.0 7.3e-21 74.6 1.0 1.2 1 0 0 1 1 1 1 Selenoprotein SelK_SelG PAC1 PF16094.5 CEG41619.1 - 4.3e-08 32.7 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF1192 PF06698.11 CEG41619.1 - 0.08 13.0 0.2 5.5 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4298 PF14131.6 CEG41619.1 - 0.44 10.5 4.0 0.83 9.7 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) FUSC PF04632.12 CEG41619.1 - 9 4.7 12.0 1.6 7.1 4.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Aa_trans PF01490.18 CEG41620.1 - 2.3e-38 132.0 18.3 3.4e-38 131.4 18.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG41620.1 - 1.7e-05 24.0 6.4 1.7e-05 24.0 6.4 2.5 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Flp1_like PF16982.5 CEG41620.1 - 0.5 9.8 6.2 1.1 8.7 6.2 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain RRN3 PF05327.11 CEG41622.1 - 1.3e-95 321.1 1.1 8.3e-95 318.4 1.1 2.2 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 fn3 PF00041.21 CEG41623.1 - 0.00023 21.4 0.1 0.00076 19.8 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG41623.1 - 0.0052 17.3 1.1 0.016 15.8 0.1 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain ZapB PF06005.12 CEG41623.1 - 0.0096 16.3 6.1 0.0096 16.3 6.1 5.0 1 1 1 2 2 2 1 Cell division protein ZapB Interfer-bind PF09294.10 CEG41623.1 - 0.13 12.6 2.7 0.23 11.8 0.0 2.5 2 1 1 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Shugoshin_N PF07558.11 CEG41623.1 - 0.9 9.5 10.6 30 4.6 0.4 5.3 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region TcdB_N PF12918.7 CEG41623.1 - 1 9.7 7.2 9.7 6.6 0.8 3.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Filament PF00038.21 CEG41623.1 - 9.9 5.6 48.6 1.4 8.5 40.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein SAMP PF05924.11 CEG41624.1 - 0.092 12.1 3.2 0.16 11.3 3.2 1.4 1 0 0 1 1 1 0 SAMP Motif Peptidase_C2 PF00648.21 CEG41625.1 - 2.3e-44 151.6 0.0 4.4e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CEG41625.1 - 5.6e-11 42.9 0.0 0.021 15.1 0.0 4.6 4 0 0 4 4 4 3 Calpain large subunit, domain III BLI1 PF17324.2 CEG41625.1 - 0.42 11.3 2.0 0.66 10.7 0.9 1.9 2 0 0 2 2 2 0 BLOC-1 interactor 1 HR1 PF02185.16 CEG41625.1 - 3.2 7.9 6.2 0.2 11.8 0.2 2.1 2 0 0 2 2 2 0 Hr1 repeat DUF3959 PF13105.6 CEG41626.1 - 0.01 15.4 0.9 0.073 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) bZIP_2 PF07716.15 CEG41626.1 - 0.013 15.5 3.9 0.03 14.4 3.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PLC-beta_C PF08703.10 CEG41626.1 - 0.013 15.5 3.0 0.02 14.9 3.0 1.2 1 0 0 1 1 1 0 PLC-beta C terminal RasGAP_C PF03836.15 CEG41626.1 - 0.019 15.1 1.6 0.03 14.5 1.6 1.2 1 0 0 1 1 1 0 RasGAP C-terminus CENP-Q PF13094.6 CEG41626.1 - 0.035 14.3 0.7 0.05 13.8 0.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HisKA PF00512.25 CEG41626.1 - 1.2 9.2 4.1 0.43 10.7 0.7 2.0 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Kinesin PF00225.23 CEG41628.1 - 3.9e-95 318.6 0.1 8.1e-95 317.5 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG41628.1 - 1.7e-45 154.6 0.0 6.9e-45 152.6 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 CEG41628.1 - 2.2 7.1 33.1 5.8 5.7 33.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA_16 PF13191.6 CEG41628.1 - 5.5 7.3 7.1 33 4.8 0.0 3.6 3 0 0 3 3 3 0 AAA ATPase domain Lectin_N PF03954.14 CEG41628.1 - 8 6.2 9.8 1.7 8.4 4.4 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain GDI PF00996.18 CEG41629.1 - 7.6e-197 654.1 0.0 9e-197 653.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor COG7 PF10191.9 CEG41632.1 - 6.5e-61 206.6 20.4 4.2e-50 170.8 18.3 3.4 1 1 1 2 2 2 2 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.12 CEG41632.1 - 0.0018 18.3 11.9 0.018 15.1 0.3 5.2 5 1 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus MetRS-N PF09635.10 CEG41632.1 - 0.0092 16.5 0.8 0.033 14.7 0.4 2.0 1 1 1 2 2 2 1 MetRS-N binding domain MIP-T3_C PF17749.1 CEG41632.1 - 0.15 12.0 1.0 0.49 10.3 0.1 2.4 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 CEG41633.1 - 1.4e-29 103.3 0.0 4.7e-29 101.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41633.1 - 7.1e-12 45.2 0.0 3.3e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG41633.1 - 4e-05 23.1 0.3 0.00022 20.6 0.3 2.1 1 1 0 1 1 1 1 Kinase-like Metallophos PF00149.28 CEG41634.1 - 9.2e-33 114.5 0.0 1.2e-32 114.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG41634.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SNF2_N PF00176.23 CEG41635.1 - 2.2e-73 247.0 0.1 6.8e-73 245.4 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DAP3 PF10236.9 CEG41635.1 - 5.5e-32 111.2 0.1 5.4e-31 107.9 0.0 2.8 3 1 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 Helicase_C PF00271.31 CEG41635.1 - 2.5e-18 66.4 0.0 8.5e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CEG41635.1 - 2e-17 63.1 0.1 6.5e-17 61.4 0.1 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CEG41635.1 - 8.9e-13 48.7 0.9 8.9e-13 48.7 0.9 4.7 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 CEG41635.1 - 1.6e-11 44.4 10.8 1.6e-11 44.4 10.8 3.7 3 0 0 3 3 1 1 HSA ResIII PF04851.15 CEG41635.1 - 1.4e-10 41.4 2.2 2.9e-09 37.2 0.0 3.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CEG41635.1 - 0.0019 18.6 0.3 0.044 14.2 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CEG41635.1 - 0.0056 16.7 0.0 0.9 9.6 0.0 3.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CEG41635.1 - 0.059 13.1 0.1 3.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CEG41635.1 - 2.4 8.4 5.7 17 5.7 0.0 4.0 5 0 0 5 5 4 0 AAA domain EF-hand_1 PF00036.32 CEG41636.1 - 2e-19 67.6 11.3 1.2e-05 24.5 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CEG41636.1 - 1.5e-18 67.0 11.2 5.9e-12 45.9 1.9 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG41636.1 - 3e-15 54.8 10.5 0.00033 20.4 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEG41636.1 - 1e-13 50.1 13.6 2.9e-05 23.3 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CEG41636.1 - 1.4e-11 44.1 12.0 1.7e-05 24.5 0.4 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEG41636.1 - 7.8e-06 26.2 4.9 0.0031 17.8 1.2 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG41636.1 - 2.6e-05 24.1 7.9 0.62 10.0 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG41636.1 - 0.025 14.9 1.3 0.16 12.3 0.2 2.6 3 1 0 3 3 3 0 EF-hand domain EF-hand_14 PF17959.1 CEG41636.1 - 0.056 13.8 0.6 9.8 6.6 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain TfuA PF07812.12 CEG41636.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 TfuA-like protein PH PF00169.29 CEG41638.1 - 1.8e-24 86.2 0.7 1.1e-14 54.9 0.0 3.0 3 0 0 3 3 3 2 PH domain VPS9 PF02204.18 CEG41638.1 - 2.6e-13 50.1 0.1 4.6e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH_3 PF14593.6 CEG41638.1 - 2e-10 40.7 0.1 1.8e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 CEG41638.1 - 5.9e-10 39.3 0.3 5e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PDZ PF00595.24 CEG41638.1 - 1.6e-07 31.6 0.0 5.3e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG41638.1 - 7e-05 22.6 0.2 0.00017 21.4 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 CEG41638.1 - 0.00026 21.4 0.5 0.058 13.8 0.2 3.7 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 CEG41638.1 - 0.0043 17.3 0.0 0.028 14.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Hemerythrin PF01814.23 CEG41638.1 - 0.023 15.3 0.0 0.082 13.5 0.0 1.9 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Mcp5_PH PF12814.7 CEG41638.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 CEG41638.1 - 0.11 12.3 0.8 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain PRKCSH-like PF12999.7 CEG41639.1 - 1.9e-35 122.2 2.1 4.1e-35 121.2 2.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like DUF4483 PF14825.6 CEG41639.1 - 5e-34 117.4 0.1 1.3e-33 116.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) PRKCSH_1 PF13015.6 CEG41639.1 - 1.9e-30 105.6 1.6 3.5e-30 104.7 1.6 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CEG41639.1 - 2.7e-08 34.7 2.2 2.7e-08 34.7 2.2 2.2 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein GCOM2 PF15328.6 CEG41639.1 - 0.017 15.5 3.2 0.035 14.5 3.2 1.5 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Mig-14 PF07395.11 CEG41639.1 - 0.051 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Mig-14 RRM_1 PF00076.22 CEG41640.1 - 2.8e-13 49.5 0.1 5.5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 CEG41640.1 - 0.028 14.1 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_5 PF13893.6 CEG41640.1 - 0.037 13.6 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG41640.1 - 0.077 13.1 0.2 0.26 11.4 0.1 2.0 1 1 1 2 2 2 0 RNA recognition motif Acyl_transf_3 PF01757.22 CEG41641.1 - 4.6e-14 52.2 35.8 7.3e-14 51.6 35.8 1.4 1 0 0 1 1 1 1 Acyltransferase family peroxidase PF00141.23 CEG41642.1 - 2.7e-41 141.8 0.0 3.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Tcp10_C PF07202.13 CEG41645.1 - 1.1e-29 103.6 0.1 1.1e-29 103.6 0.1 2.4 3 0 0 3 3 3 1 T-complex protein 10 C-terminus DAGK_cat PF00781.24 CEG41645.1 - 1.9e-26 92.2 0.0 3.8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Retinin_C PF04527.12 CEG41647.1 - 0.078 13.2 0.6 0.24 11.7 0.4 1.8 1 1 1 2 2 2 0 Drosophila Retinin like protein Glyco_hydro81C PF17652.1 CEG41648.1 - 1.2e-121 406.2 7.3 1.9e-121 405.6 7.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG41648.1 - 1e-43 149.7 0.4 1.6e-43 149.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Gelsolin PF00626.22 CEG41651.1 - 3.7e-78 257.4 0.0 5.6e-15 55.0 0.0 6.4 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 CEG41651.1 - 3.2e-14 52.7 4.7 8e-14 51.4 4.7 1.7 1 0 0 1 1 1 1 Villin headpiece domain Methyltransf_31 PF13847.6 CEG41652.1 - 1e-06 28.6 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG41652.1 - 8e-06 25.3 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEG41652.1 - 2.6e-05 24.8 0.0 3.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEG41652.1 - 0.00022 20.8 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 CEG41652.1 - 0.00027 20.9 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG41652.1 - 0.00052 20.6 0.0 0.00068 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG41652.1 - 0.0073 16.1 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CEG41652.1 - 0.0091 15.6 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 CEG41652.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 CEG41652.1 - 0.016 16.0 0.0 0.021 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CEG41652.1 - 0.044 13.6 0.0 0.046 13.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CEG41652.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 CEG41652.1 - 0.16 12.0 0.1 0.2 11.6 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 CEG41652.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase LRR_8 PF13855.6 CEG41653.1 - 3.7e-28 97.0 32.3 6.8e-12 45.0 3.5 4.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEG41653.1 - 4.3e-25 87.4 60.8 5.5e-09 36.2 0.4 6.2 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG41653.1 - 5.8e-15 55.2 16.0 1.7e-07 30.9 3.1 3.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CEG41653.1 - 0.072 13.2 28.8 0.93 9.7 0.2 9.0 10 0 0 10 10 10 0 Leucine Rich repeat Thioredoxin_2 PF13098.6 CEG41653.1 - 0.076 13.5 0.8 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain UCR_TM PF02921.14 CEG41656.1 - 4.7e-14 52.6 0.3 9.7e-14 51.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 CEG41656.1 - 3.5e-12 46.1 0.0 6.5e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2516 PF10724.9 CEG41656.1 - 0.11 12.8 0.0 0.57 10.5 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) Mrx7 PF10906.8 CEG41657.1 - 0.0077 16.5 0.9 0.01 16.1 0.2 1.6 2 0 0 2 2 2 1 MIOREX complex component 7 Ras PF00071.22 CEG41658.1 - 3e-40 137.5 0.2 6.4e-40 136.4 0.2 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CEG41658.1 - 1.5e-27 96.2 0.1 1.2e-26 93.3 0.1 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG41658.1 - 2.3e-10 40.2 0.0 4.2e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEG41658.1 - 2e-05 24.2 0.1 2.6e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG41658.1 - 3.2e-05 24.0 0.2 0.00011 22.2 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 CEG41658.1 - 0.00047 19.5 0.1 0.00099 18.5 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 CEG41658.1 - 0.0009 19.7 0.1 0.0021 18.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 CEG41658.1 - 0.0009 18.7 0.0 0.0018 17.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG41658.1 - 0.0015 18.5 0.1 0.014 15.3 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 CEG41658.1 - 0.0064 16.2 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CEG41658.1 - 0.0096 15.5 0.1 0.75 9.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CEG41658.1 - 0.017 15.4 0.0 0.045 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEG41658.1 - 0.025 14.6 0.0 0.077 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CEG41658.1 - 0.031 14.2 0.2 0.33 10.9 0.2 2.3 1 1 0 1 1 1 0 NTPase MCM PF00493.23 CEG41658.1 - 0.039 13.1 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_19 PF13245.6 CEG41658.1 - 0.047 14.0 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CEG41658.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 CEG41658.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 CEG41658.1 - 0.067 13.7 0.1 0.1 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CEG41658.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CEG41658.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CEG41658.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CEG41658.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain LRR_8 PF13855.6 CEG41661.1 - 2.2e-25 88.1 48.2 8.6e-11 41.4 2.4 5.3 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CEG41661.1 - 6.5e-18 64.5 27.4 6.4e-05 23.2 1.9 5.9 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG41661.1 - 5.2e-13 47.6 29.7 1.8 9.4 0.2 9.6 7 2 2 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.6 CEG41661.1 - 7.1e-06 25.7 20.4 0.5 10.6 0.1 7.9 9 0 0 9 9 9 3 Leucine Rich repeat FNIP PF05725.12 CEG41661.1 - 0.0026 17.9 0.0 2 8.7 0.0 4.1 3 2 0 3 3 3 1 FNIP Repeat DUF3338 PF11819.8 CEG41661.1 - 0.011 15.7 0.7 0.59 10.1 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) LRR_3 PF07725.12 CEG41661.1 - 0.19 11.6 4.1 21 5.1 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat RRP36 PF06102.12 CEG41662.1 - 4.4e-44 150.4 32.9 5.6e-44 150.0 32.9 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 CarbopepD_reg_2 PF13715.6 CEG41662.1 - 0.048 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 CarboxypepD_reg-like domain DUF3868 PF12984.7 CEG41663.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3868) RT_RNaseH PF17917.1 CEG41667.1 - 1.7e-29 102.2 0.0 4.2e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEG41667.1 - 3.1e-18 65.6 1.1 6.7e-18 64.6 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEG41667.1 - 7.4e-18 64.4 0.0 2.2e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEG41667.1 - 2.8e-13 50.1 0.1 8e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEG41667.1 - 0.00019 21.3 0.8 0.00046 20.0 0.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_3 PF13456.6 CEG41667.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Retrotrans_gag PF03732.17 CEG41668.1 - 3.4e-09 36.8 0.1 3.4e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 CEG41668.1 - 9.4e-07 28.6 0.0 3.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEG41668.1 - 0.00012 22.0 0.8 0.00022 21.1 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CEG41668.1 - 0.00045 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.6 CEG41668.1 - 0.74 9.6 2.7 1.1 9.1 0.8 2.3 3 0 0 3 3 3 0 Zinc knuckle AvrPtoB_bdg PF16847.5 CEG41672.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain SpoIIE PF07228.12 CEG41673.1 - 8.4e-06 25.8 0.1 6.2e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CEG41673.1 - 0.00015 21.5 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SET PF00856.28 CEG41674.1 - 2.5e-15 57.3 0.5 2.6e-14 54.0 0.0 2.8 2 2 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CEG41674.1 - 7e-11 42.4 14.5 7e-11 42.4 14.5 2.9 2 1 0 2 2 2 1 CXC domain STAT_bind PF02864.15 CEG41675.1 - 0.47 11.0 3.0 4.4 7.9 0.0 3.1 2 1 1 3 3 3 0 STAT protein, DNA binding domain PH_8 PF15409.6 CEG41676.1 - 0.0034 17.6 0.1 0.0089 16.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Arteri_Gl PF00951.18 CEG41679.1 - 0.02 14.7 2.3 0.026 14.4 2.3 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein CLASP_N PF12348.8 CEG41692.1 - 0.0063 16.1 0.6 0.18 11.4 0.0 2.8 3 0 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.8 CEG41692.1 - 0.026 14.4 0.0 35 4.3 0.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF3385) HEAT PF02985.22 CEG41692.1 - 0.14 12.5 4.6 18 6.0 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Tti2 PF10521.9 CEG41692.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Tti2 family 2-Hacid_dh_C PF02826.19 CEG41693.1 - 1.9e-44 151.2 0.0 2.7e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CEG41693.1 - 2.6e-05 24.4 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEG41693.1 - 0.0021 18.6 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 CEG41693.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CEG41693.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 CEG41693.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain ThiF PF00899.21 CEG41693.1 - 0.082 12.3 0.4 1.8 7.9 0.1 2.2 1 1 1 2 2 2 0 ThiF family Sacchrp_dh_NADP PF03435.18 CEG41693.1 - 0.098 12.9 0.4 0.39 11.0 0.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PIF6 PF05341.11 CEG41693.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Per os infectivity factor 6 Ricin_B_lectin PF00652.22 CEG41694.1 - 0.0057 16.9 0.1 0.0074 16.5 0.1 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Arm PF00514.23 CEG41695.1 - 1.6e-07 31.1 9.6 0.081 13.0 0.1 6.1 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEG41695.1 - 0.0043 17.4 0.7 0.065 13.6 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Atx10homo_assoc PF09759.9 CEG41695.1 - 0.0051 16.8 0.9 1.2 9.2 0.1 3.2 1 1 1 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3323 PF11796.8 CEG41695.1 - 0.023 14.6 1.5 0.06 13.2 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Terminase_4 PF05119.12 CEG41695.1 - 0.024 15.1 1.2 1 9.8 0.7 3.0 3 0 0 3 3 3 0 Phage terminase, small subunit Fmp27_WPPW PF10359.9 CEG41695.1 - 0.1 11.4 4.5 0.16 10.8 4.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NAP PF00956.18 CEG41695.1 - 0.34 10.1 3.8 0.75 8.9 3.8 1.5 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF4472 PF14739.6 CEG41695.1 - 1 10.1 11.1 3.9 8.3 11.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) HSP90 PF00183.18 CEG41696.1 - 3.8e-236 785.0 27.7 4.3e-236 784.8 27.7 1.0 1 0 0 1 1 1 1 Hsp90 protein LOH1CR12 PF10158.9 CEG41696.1 - 0.016 15.2 1.1 0.2 11.7 0.1 2.6 2 0 0 2 2 2 0 Tumour suppressor protein DUF2052 PF09747.9 CEG41696.1 - 0.22 11.6 18.1 0.017 15.3 7.5 2.8 2 1 1 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Pyr_redox_2 PF07992.14 CEG41697.1 - 7.7e-48 163.2 1.0 1.2e-47 162.6 1.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG41697.1 - 1.7e-26 92.6 0.2 7.1e-26 90.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEG41697.1 - 3.6e-17 62.7 4.3 2e-13 50.7 0.6 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG41697.1 - 2.8e-09 37.1 0.3 3e-05 24.2 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CEG41697.1 - 1.8e-08 34.2 0.0 3.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG41697.1 - 1.4e-07 30.6 5.7 1.2e-05 24.2 0.2 3.1 2 1 1 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CEG41697.1 - 3.1e-07 29.9 0.3 0.00064 19.1 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CEG41697.1 - 9e-07 28.4 1.7 0.019 14.2 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEG41697.1 - 4.1e-06 26.1 0.5 4.1e-06 26.1 0.5 2.7 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 CEG41697.1 - 5.1e-06 25.8 2.8 0.0021 17.2 0.1 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A 3HCDH_N PF02737.18 CEG41697.1 - 5e-05 23.3 2.5 0.0059 16.5 0.3 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CEG41697.1 - 6.3e-05 22.7 0.5 0.0098 15.5 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEG41697.1 - 0.00012 21.5 0.3 0.01 15.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 CEG41697.1 - 0.00099 19.3 0.2 0.16 12.3 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CEG41697.1 - 0.0015 18.1 1.1 1.3 8.5 0.1 3.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CEG41697.1 - 0.0043 16.4 1.8 0.2 10.8 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 CEG41697.1 - 0.015 14.3 4.9 0.26 10.3 0.3 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein XdhC_C PF13478.6 CEG41697.1 - 0.017 15.6 0.1 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DnaJ PF00226.31 CEG41700.1 - 4.8e-14 52.2 0.4 4.8e-14 52.2 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CEG41700.1 - 0.00015 21.9 0.1 0.00055 20.1 0.1 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Auxin_repressed PF05564.12 CEG41700.1 - 0.051 14.3 0.1 0.12 13.1 0.1 1.6 1 1 0 1 1 1 0 Dormancy/auxin associated protein zf-met PF12874.7 CEG41700.1 - 0.059 13.8 0.1 0.17 12.3 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEG41700.1 - 0.17 12.8 2.7 0.24 12.3 0.6 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger Borrelia_P83 PF05262.11 CEG41700.1 - 0.26 9.7 7.5 0.33 9.4 7.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 CEG41700.1 - 2 8.4 9.0 3.4 7.7 7.8 2.0 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Oxidored_FMN PF00724.20 CEG41701.1 - 3.8e-76 256.6 0.0 6.1e-76 255.9 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PGM1_C PF18105.1 CEG41701.1 - 0.077 12.5 1.5 0.16 11.5 0.1 2.3 3 0 0 3 3 3 0 PGM1 C-terminal domain Sulfatase PF00884.23 CEG41703.1 - 1.9e-28 99.8 0.1 2.7e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CEG41703.1 - 0.00013 20.7 0.0 0.00025 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CEG41703.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase PF00069.25 CEG41704.1 - 2e-72 243.8 0.0 2.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41704.1 - 7.8e-42 143.3 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG41704.1 - 1.8e-05 24.2 0.1 0.00023 20.6 0.1 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG41704.1 - 0.0029 17.0 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RXLR_WY PF18634.1 CEG41705.1 - 0.00059 19.7 0.6 17 5.5 0.1 3.4 3 0 0 3 3 3 3 RXLR phytopathogen effector protein WY-domain WD40 PF00400.32 CEG41706.1 - 1.1e-40 136.8 36.3 4e-06 27.4 0.2 11.3 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41706.1 - 6.7e-20 71.2 4.5 0.0058 16.9 0.0 7.6 6 2 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CEG41706.1 - 2.8e-14 53.3 4.6 5.4e-14 52.4 4.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 CEG41706.1 - 0.00055 19.3 0.0 0.31 10.3 0.1 4.6 4 2 1 5 5 5 1 WD40-like domain RAB3GAP2_N PF14655.6 CEG41706.1 - 0.023 14.0 0.0 4.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CEG41706.1 - 0.038 12.6 7.7 1.6 7.2 0.3 3.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF728 PF05304.12 CEG41706.1 - 0.052 13.4 0.2 0.19 11.6 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF728) NHL PF01436.21 CEG41706.1 - 0.12 12.5 0.1 2.3 8.4 0.0 3.2 2 0 0 2 2 2 0 NHL repeat DUF2229 PF09989.9 CEG41706.1 - 0.13 11.9 1.6 0.3 10.7 1.6 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2956 PF11169.8 CEG41706.1 - 0.4 10.9 13.8 1.3 9.2 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Mit_KHE1 PF10173.9 CEG41706.1 - 3.3 7.7 4.5 8.1 6.5 4.5 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related AIF_C PF14721.6 CEG41706.1 - 4.7 7.6 12.7 5.5 7.4 2.6 2.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ANAPC5 PF12862.7 CEG41708.1 - 3.8e-21 74.9 0.8 3.8e-21 74.9 0.8 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 CEG41708.1 - 0.0013 19.2 9.2 2.5 8.7 0.4 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG41708.1 - 0.0039 17.5 7.3 2.2 8.6 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SPOB_a PF14689.6 CEG41708.1 - 0.012 15.3 0.3 9.4 6.0 0.1 4.3 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_2 PF07719.17 CEG41708.1 - 0.53 10.5 4.3 40 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NTF2 PF02136.20 CEG41709.1 - 0.11 13.0 0.0 0.36 11.4 0.0 1.8 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Abhydrolase_6 PF12697.7 CEG41712.1 - 0.072 13.7 0.0 0.088 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CEG41712.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1512 PF07431.12 CEG41712.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Acetyltransf_3 PF13302.7 CEG41713.1 - 2e-25 90.1 0.0 2.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG41713.1 - 4.8e-07 30.0 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CEG41713.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEG41713.1 - 7.4e-06 26.2 0.4 9.2e-06 25.9 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG41713.1 - 0.00051 20.0 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 CEG41713.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase RabGAP-TBC PF00566.18 CEG41714.1 - 5.9e-49 166.6 0.1 1.1e-48 165.8 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DEC-1_N PF04625.13 CEG41714.1 - 0.03 13.4 1.3 0.052 12.6 1.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region APG6_N PF17675.1 CEG41715.1 - 0.00042 20.9 2.4 0.00042 20.9 2.4 4.9 1 1 2 3 3 3 1 Apg6 coiled-coil region Strep_SA_rep PF06696.11 CEG41715.1 - 0.0084 16.1 2.8 0.0084 16.1 2.8 3.5 3 0 0 3 3 3 1 Streptococcal surface antigen repeat CENP-F_leu_zip PF10473.9 CEG41715.1 - 0.0085 16.1 2.5 0.0085 16.1 2.5 4.0 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 CEG41715.1 - 9.5 6.7 37.1 2.3 8.7 3.0 5.6 3 1 2 5 5 5 0 Snapin/Pallidin HA2 PF04408.23 CEG41717.1 - 4.4e-22 78.4 0.0 4.4e-22 78.4 0.0 3.6 3 2 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG41717.1 - 1.6e-21 76.4 0.1 4.5e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG41717.1 - 9.6e-13 48.5 0.0 2.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG41717.1 - 1.2e-06 28.5 0.1 3.7e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG41717.1 - 6.2e-05 23.3 0.0 0.00029 21.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG41717.1 - 0.00021 21.1 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEG41717.1 - 0.00069 18.8 0.0 0.0017 17.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CEG41717.1 - 0.0046 17.3 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CEG41717.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain GCP_C_terminal PF04130.13 CEG41718.1 - 1.2e-30 107.1 20.2 1.3e-30 106.9 14.5 3.1 2 1 0 2 2 2 2 Gamma tubulin complex component C-terminal CHDCT2 PF08074.11 CEG41719.1 - 2.2 8.4 7.4 0.24 11.6 2.0 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF2807 PF10988.8 CEG41720.1 - 6.7e-14 52.1 16.0 9.5e-13 48.3 3.1 2.5 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain G8 PF10162.9 CEG41720.1 - 0.012 15.7 0.5 0.11 12.5 0.5 2.4 1 1 0 1 1 1 0 G8 domain Myb_DNA-binding PF00249.31 CEG41723.1 - 5.5e-36 122.5 13.0 4e-13 49.3 0.9 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG41723.1 - 2.7e-34 117.2 4.7 5.7e-15 55.3 0.1 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 CEG41723.1 - 0.0029 17.6 2.3 5.9 7.1 0.1 3.8 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sigma70_r4_2 PF08281.12 CEG41723.1 - 0.0033 17.1 0.3 0.059 13.1 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Ribosom_S12_S23 PF00164.25 CEG41723.1 - 0.05 13.2 0.0 0.68 9.6 0.0 2.8 3 1 1 4 4 4 0 Ribosomal protein S12/S23 Myb_DNA-bind_4 PF13837.6 CEG41723.1 - 0.37 11.2 8.6 2.3 8.7 0.1 3.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 CEG41724.1 - 1.1e-32 113.3 0.0 1.7e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG41724.1 - 4.1e-25 88.6 0.0 6.7e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NABP PF07990.12 CEG41724.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP YL1 PF05764.13 CEG41725.1 - 0.0074 16.4 19.4 0.013 15.7 19.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SLC12 PF03522.15 CEG41725.1 - 0.13 11.2 14.1 0.26 10.3 11.2 2.0 2 0 0 2 2 2 0 Solute carrier family 12 MMR1 PF08505.10 CEG41725.1 - 0.2 11.9 23.8 0.032 14.5 16.1 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein LMBR1 PF04791.16 CEG41725.1 - 0.4 9.5 3.3 0.5 9.2 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF100_C PF13299.6 CEG41725.1 - 0.55 10.4 15.9 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CEG41725.1 - 0.65 9.4 18.2 2.1 7.8 12.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 CEG41725.1 - 1.3 7.7 20.9 1 8.1 1.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FCP1_C PF09309.10 CEG41725.1 - 1.4 8.8 19.9 0.2 11.5 2.6 2.6 2 0 0 2 2 2 0 FCP1, C-terminal RR_TM4-6 PF06459.12 CEG41725.1 - 2.2 8.0 23.1 5 6.9 1.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MecA PF05389.12 CEG41725.1 - 2.8 7.5 14.6 0.09 12.4 5.7 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Connexin PF00029.19 CEG41725.1 - 3 7.5 16.2 10 5.8 0.0 2.1 2 0 0 2 2 2 0 Connexin Peroxin-13_N PF04088.13 CEG41725.1 - 3.4 7.9 9.9 41 4.4 0.0 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AIF_C PF14721.6 CEG41725.1 - 3.9 7.8 17.4 0.62 10.4 7.3 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.22 CEG41725.1 - 4.6 6.4 10.3 1.4 8.1 3.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter EIIBC-GUT_N PF03612.14 CEG41725.1 - 5.8 6.6 19.3 5 6.8 0.1 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TERB2 PF15101.6 CEG41725.1 - 6.2 6.8 25.5 2 8.4 18.4 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 FAM176 PF14851.6 CEG41725.1 - 8.7 6.0 17.3 0.97 9.1 0.4 2.2 2 0 0 2 2 2 0 FAM176 family Eapp_C PF10238.9 CEG41725.1 - 9.1 6.3 18.7 17 5.5 12.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein CCSAP PF15748.5 CEG41725.1 - 9.7 6.3 26.4 1.1 9.3 13.3 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated OATP PF03137.20 CEG41725.1 - 9.9 4.3 11.5 4.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family C2 PF00168.30 CEG41727.1 - 2.5e-12 47.0 0.0 4.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain YjhX_toxin PF09857.9 CEG41727.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair DNA_pol_E_B PF04042.16 CEG41728.1 - 2.2e-40 138.3 0.3 3.6e-40 137.6 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 CEG41728.1 - 9.2e-06 25.9 0.2 2.2e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal TPR_10 PF13374.6 CEG41729.1 - 0.016 15.1 2.2 0.3 11.0 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG41729.1 - 0.085 13.0 2.3 20 5.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG41729.1 - 0.57 11.2 8.9 1.4 9.9 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG41729.1 - 6.5 7.5 7.9 6.6 7.5 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 CEG41730.1 - 0.00023 21.4 6.3 0.00057 20.1 6.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG41730.1 - 0.0011 19.3 9.0 0.0021 18.3 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEG41730.1 - 0.0012 18.5 3.3 0.0026 17.5 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEG41730.1 - 0.0095 15.8 9.5 0.018 14.9 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG41730.1 - 0.028 14.5 4.9 0.11 12.6 5.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEG41730.1 - 0.039 14.0 5.8 0.096 12.7 5.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CEG41730.1 - 0.14 11.8 3.8 0.3 10.8 3.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEG41730.1 - 0.16 11.8 6.6 0.31 10.9 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CEG41730.1 - 0.19 11.6 4.9 0.32 10.9 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 CEG41730.1 - 1.3 9.2 3.8 0.45 10.7 0.7 1.8 2 0 0 2 2 1 0 Zinc ribbon domain PHD PF00628.29 CEG41730.1 - 2.2 8.2 5.0 5.1 7.1 5.0 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 CEG41730.1 - 4.4 7.3 6.0 9.6 6.3 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG41730.1 - 6.6 6.7 8.1 13 5.7 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CEG41730.1 - 7.8 6.6 9.5 16 5.6 9.5 1.6 1 0 0 1 1 1 0 Zinc-finger Foie-gras_1 PF11817.8 CEG41732.1 - 0.0003 20.5 0.5 0.00055 19.6 0.5 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 HA PF03457.14 CEG41733.1 - 4.7e-26 90.9 6.0 2.3e-05 24.6 0.2 5.3 5 0 0 5 5 5 4 Helicase associated domain Ion_trans PF00520.31 CEG41734.1 - 3.6e-19 69.0 9.5 3.6e-19 69.0 9.5 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 CEG41734.1 - 1.7e-12 47.1 4.2 3.9e-12 46.0 4.2 1.6 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 CEG41734.1 - 3.3e-10 39.9 0.1 8.8e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain CpcD PF01383.21 CEG41734.1 - 0.089 13.1 0.0 0.4 11.0 0.0 2.2 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain DnaJ PF00226.31 CEG41735.1 - 1.3e-22 79.6 0.5 3.2e-22 78.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4458 PF14660.6 CEG41736.1 - 0.23 11.7 1.4 0.8 10.0 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) MtN3_slv PF03083.16 CEG41737.1 - 1.3e-29 102.1 22.4 2.6e-18 65.8 6.2 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF1772 PF08592.11 CEG41737.1 - 0.023 15.0 3.3 0.023 15.0 3.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Chromo PF00385.24 CEG41739.1 - 0.00088 19.1 2.2 0.00088 19.1 2.2 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MutS_V PF00488.21 CEG41742.1 - 1.7e-74 250.0 0.1 2.8e-74 249.2 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEG41742.1 - 9.8e-33 114.0 0.3 3.6e-32 112.1 0.3 2.0 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CEG41742.1 - 5e-29 100.8 0.1 1e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CEG41742.1 - 1.2e-15 57.6 0.3 3.7e-15 56.1 0.3 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CEG41742.1 - 3e-09 37.3 0.7 1.8e-08 34.8 0.1 2.7 2 1 0 2 2 2 1 MutS domain II Ribosomal_L22 PF00237.19 CEG41743.1 - 2.2e-38 130.6 0.1 3.3e-38 130.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Lambda_Kil PF06301.11 CEG41743.1 - 0.12 11.9 0.3 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage lambda Kil protein DEK_C PF08766.11 CEG41744.1 - 0.00066 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain CHZ PF09649.10 CEG41744.1 - 0.00086 18.7 0.8 0.0035 16.8 0.8 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ TRAM_LAG1_CLN8 PF03798.16 CEG41745.1 - 5.2e-35 121.0 16.8 5.2e-35 121.0 16.8 1.5 2 0 0 2 2 2 1 TLC domain HTH_Tnp_Tc5 PF03221.16 CEG41747.1 - 2.7e-06 27.3 0.1 6.6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 CEG41747.1 - 0.012 15.2 0.1 0.042 13.5 0.1 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.10 CEG41747.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain YvbH_ext PF11724.8 CEG41747.1 - 0.057 13.7 1.7 6.5 7.2 0.1 3.2 2 0 0 2 2 2 0 YvbH-like oligomerisation region HTH_24 PF13412.6 CEG41747.1 - 0.11 12.1 0.2 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SNase PF00565.17 CEG41749.1 - 0.039 14.4 0.2 0.32 11.5 0.2 2.4 1 1 0 1 1 1 0 Staphylococcal nuclease homologue PMSR PF01625.21 CEG41750.1 - 1.1e-63 214.0 1.5 1.4e-63 213.7 1.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase IPT PF01745.16 CEG41752.1 - 0.13 11.6 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase SieB PF14163.6 CEG41754.1 - 0.045 13.2 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B RXLR_WY PF18634.1 CEG41757.1 - 3.4e-13 49.3 6.9 8.5e-06 25.6 1.2 4.3 4 0 0 4 4 4 2 RXLR phytopathogen effector protein WY-domain EF-hand_14 PF17959.1 CEG41757.1 - 0.044 14.1 0.4 0.53 10.7 0.0 2.8 3 1 0 3 3 3 0 EF-hand domain RXLR PF16810.5 CEG41757.1 - 0.055 13.9 0.4 4.2 7.8 0.0 2.8 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity SIL1 PF16782.5 CEG41757.1 - 0.15 11.3 5.5 2.7 7.1 0.1 3.0 3 0 0 3 3 3 0 Nucleotide exchange factor SIL1 5_3_exonuc PF01367.20 CEG41759.1 - 0.0073 16.9 0.0 0.068 13.8 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold ERCC4 PF02732.15 CEG41759.1 - 0.016 15.4 0.2 0.035 14.3 0.2 1.7 1 0 0 1 1 1 0 ERCC4 domain PilZ PF07238.14 CEG41759.1 - 0.038 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 PilZ domain CENP-X PF09415.10 CEG41759.1 - 0.076 13.3 0.2 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Myb_DNA-binding PF00249.31 CEG41760.1 - 1.1e-39 134.3 9.0 8.5e-13 48.3 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG41760.1 - 4.5e-28 97.3 1.0 1.1e-12 47.9 0.0 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG41760.1 - 2e-06 27.6 1.0 1e-05 25.4 0.3 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 CEG41760.1 - 0.011 15.7 0.0 8.5 6.4 0.0 3.3 2 1 1 3 3 3 0 SLIDE DUF3012 PF11216.8 CEG41760.1 - 0.058 13.4 0.4 0.24 11.5 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Rap1_C PF11626.8 CEG41760.1 - 0.17 12.0 2.6 24 5.1 2.6 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Kelch_4 PF13418.6 CEG41761.1 - 1.2e-32 111.6 14.2 4.7e-09 36.1 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CEG41761.1 - 7.7e-32 109.0 10.5 2.3e-08 34.1 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG41761.1 - 8.1e-31 105.3 5.6 9.7e-06 25.7 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CEG41761.1 - 1.5e-30 104.7 0.3 3.3e-06 27.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CEG41761.1 - 2.9e-24 84.4 9.9 4.8e-09 35.7 0.5 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CEG41761.1 - 7.2e-21 73.3 11.9 2.2e-07 30.6 0.4 6.3 6 0 0 6 6 6 4 Kelch motif DUF4551 PF15087.6 CEG41761.1 - 0.39 9.5 2.6 0.51 9.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GRAM PF02893.20 CEG41762.1 - 0.0031 17.4 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 GRAM domain DUF4996 PF16387.5 CEG41764.1 - 0.019 15.5 1.3 0.02 15.4 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DegQ PF08181.11 CEG41764.1 - 0.051 13.7 1.2 0.11 12.6 0.6 2.0 1 1 1 2 2 2 0 DegQ (SacQ) family EF-hand_1 PF00036.32 CEG41765.1 - 1.3e-172 546.9 66.8 2.3e-06 26.7 0.0 33.0 33 0 0 33 33 33 29 EF hand EF-hand_7 PF13499.6 CEG41765.1 - 1.6e-144 470.6 74.6 1.4e-11 44.7 0.0 22.1 20 2 3 23 23 22 19 EF-hand domain pair EF-hand_6 PF13405.6 CEG41765.1 - 7.2e-142 449.5 76.0 5.2e-05 22.9 0.0 33.2 31 0 0 31 31 31 29 EF-hand domain EF-hand_5 PF13202.6 CEG41765.1 - 6.9e-108 347.8 82.7 5.2e-05 22.6 0.2 31.4 30 0 0 30 30 30 26 EF hand EF-hand_8 PF13833.6 CEG41765.1 - 2.8e-60 200.0 88.8 0.0039 17.0 0.0 33.4 27 7 5 33 33 33 19 EF-hand domain pair EF-hand_4 PF12763.7 CEG41765.1 - 9.7e-17 60.8 63.7 0.011 15.6 0.1 22.2 11 9 9 23 23 23 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG41765.1 - 1.9e-16 60.1 21.4 0.44 10.9 0.0 14.7 12 6 1 13 13 13 5 EF-hand domain EF-hand_2 PF09068.11 CEG41765.1 - 3.3e-14 53.1 4.0 0.63 10.2 0.2 11.6 9 4 1 10 10 9 3 EF hand Pro_isomerase PF00160.21 CEG41765.1 - 0.0015 18.8 0.1 0.035 14.4 0.0 2.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1707 PF08044.11 CEG41765.1 - 0.014 15.4 2.7 26 5.0 0.0 7.6 9 0 0 9 9 8 0 Domain of unknown function (DUF1707) MA3 PF02847.17 CEG41765.1 - 0.031 14.3 0.4 5.8 6.9 0.1 3.0 2 0 0 2 2 2 0 MA3 domain p25-alpha PF05517.12 CEG41765.1 - 0.045 13.9 2.6 18 5.4 0.0 4.3 5 0 0 5 5 5 0 p25-alpha EF-hand_14 PF17959.1 CEG41765.1 - 0.86 10.0 8.1 2.5e+02 2.1 0.0 7.4 8 0 0 8 8 6 0 EF-hand domain EF-hand_10 PF14788.6 CEG41765.1 - 5.1 7.1 22.4 18 5.3 0.0 9.8 12 0 0 12 12 12 0 EF hand PAPS_reduct PF01507.19 CEG41767.1 - 2.9e-22 79.5 0.0 4.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 CEG41767.1 - 9.5e-15 54.6 0.5 8.8e-14 51.5 0.1 2.2 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 CEG41767.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CEG41767.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 CEG41767.1 - 0.056 13.3 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein SH3BGR PF04908.15 CEG41767.1 - 0.091 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Casc1_N PF15927.5 CEG41768.1 - 1.6e-28 99.8 18.8 1.6e-28 99.8 18.8 2.6 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus ERM PF00769.19 CEG41768.1 - 0.0087 15.9 16.8 0.015 15.1 16.8 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MAP7 PF05672.11 CEG41768.1 - 0.37 10.5 27.3 0.67 9.6 27.3 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family PHD PF00628.29 CEG41769.1 - 2e-06 27.6 5.2 2e-06 27.6 5.2 3.5 3 1 0 3 3 3 2 PHD-finger MBT PF02820.18 CEG41769.1 - 0.028 14.8 0.1 0.077 13.4 0.1 1.7 1 0 0 1 1 1 0 mbt repeat FOP_dimer PF09398.10 CEG41772.1 - 1.9e-14 53.7 0.1 3.1e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 CEG41772.1 - 4.1e-10 38.5 0.1 7.2e-10 37.7 0.1 1.4 1 0 0 1 1 1 1 LisH Meth_synt_2 PF01717.18 CEG41774.1 - 4.7e-144 479.6 0.0 3.5e-141 470.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CEG41774.1 - 1.5e-94 317.0 0.0 8.3e-89 298.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain UPF0016 PF01169.19 CEG41776.1 - 6.9e-44 148.1 22.5 6.7e-22 77.6 7.5 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 CEG41776.1 - 4.7e-06 26.4 2.1 8.5e-05 22.3 0.1 2.9 3 0 0 3 3 3 1 Integral membrane protein TerC family Mntp PF02659.15 CEG41776.1 - 0.00014 21.7 6.0 0.0011 18.8 0.1 2.6 2 0 0 2 2 2 1 Putative manganese efflux pump EF-hand_1 PF00036.32 CEG41776.1 - 0.00056 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CEG41776.1 - 0.0065 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG41776.1 - 0.041 13.8 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 CEG41776.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 CEG41776.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair DUF3995 PF13160.6 CEG41776.1 - 2.1 8.8 11.1 5.9 7.3 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) Rho_N PF07498.12 CEG41778.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Trypsin PF00089.26 CEG41779.1 - 1.2e-45 156.1 0.1 1.3e-45 155.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG41779.1 - 3.4e-09 37.8 0.1 5.1e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain zf-primase PF09329.11 CEG41780.1 - 1.4e-09 37.6 0.7 2.4e-09 36.8 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger Gal_mutarotas_3 PF18080.1 CEG41780.1 - 0.38 10.7 3.3 0.23 11.4 0.5 2.1 2 1 0 2 2 2 0 Galactose mutarotase-like fold domain zf-RING-like PF08746.11 CEG41781.1 - 0.035 14.4 1.1 0.052 13.9 0.2 1.8 2 0 0 2 2 2 0 RING-like domain DUF4556 PF15094.6 CEG41782.1 - 0.056 12.7 0.1 0.089 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) CAP PF00188.26 CEG41784.1 - 7.3e-18 65.6 2.2 7.3e-18 65.6 2.2 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ASFV_J13L PF05568.11 CEG41784.1 - 3.1 7.5 7.5 0.7 9.6 3.2 2.0 2 1 1 3 3 3 0 African swine fever virus J13L protein Polyoma_coat2 PF00761.20 CEG41785.1 - 0.39 10.4 3.4 0.1 12.3 0.4 1.5 2 0 0 2 2 2 0 Polyomavirus coat protein Macoilin PF09726.9 CEG41785.1 - 2 6.9 10.9 2.7 6.5 10.9 1.2 1 0 0 1 1 1 0 Macoilin family Peptidase_S66C PF17676.1 CEG41789.1 - 0.15 12.6 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain SM-ATX PF14438.6 CEG41791.1 - 0.0035 17.4 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 CEG41791.1 - 0.026 14.2 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 LSM domain RVT_2 PF07727.14 CEG41793.1 - 0.00055 19.7 0.0 0.00063 19.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GerD PF17898.1 CEG41794.1 - 0.43 10.5 11.2 6.8 6.7 0.9 3.9 3 1 1 4 4 4 0 Spore germination GerD central core domain NFACT-C PF11923.8 CEG41796.1 - 3.2e-31 107.4 0.0 3.2e-31 107.4 0.0 3.0 2 1 1 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 CEG41796.1 - 5.6e-05 23.7 0.0 0.00016 22.2 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain tRNA_edit PF04073.15 CEG41799.1 - 1.6e-07 31.4 0.0 2.6e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Aminoacyl-tRNA editing domain PPTA PF01239.22 CEG41799.1 - 0.016 14.9 0.2 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat AAA_assoc_C PF09821.9 CEG41801.1 - 0.0062 17.1 0.2 0.014 15.9 0.2 1.6 1 0 0 1 1 1 1 C-terminal AAA-associated domain Siah-Interact_N PF09032.11 CEG41801.1 - 0.017 15.4 0.4 1 9.7 0.1 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal Mlo PF03094.15 CEG41804.1 - 7e-07 28.0 4.9 0.00038 19.0 0.5 2.8 3 0 0 3 3 3 2 Mlo family Gag_p10 PF02337.17 CEG41804.1 - 0.045 13.7 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Retroviral GAG p10 protein UPF0242 PF06785.11 CEG41804.1 - 0.092 12.8 0.1 0.092 12.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus EF-hand_6 PF13405.6 CEG41804.1 - 0.14 12.1 0.1 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain DUF5418 PF17439.2 CEG41804.1 - 7.2 6.7 8.6 1.5 8.9 4.4 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5418) Sec3_C PF09763.9 CEG41805.1 - 1.5e-30 106.2 22.1 2e-24 86.0 0.7 3.3 2 1 1 3 3 3 3 Exocyst complex component Sec3 DUF4509 PF14970.6 CEG41805.1 - 0.016 15.1 0.5 0.053 13.5 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Radical_SAM PF04055.21 CEG41806.1 - 2.2e-18 67.2 0.0 5e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 CEG41806.1 - 2.3e-17 62.8 0.1 8.7e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 His_Phos_1 PF00300.22 CEG41808.1 - 7.4e-19 68.2 0.2 3e-18 66.2 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ArfA PF03889.13 CEG41808.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A Lin-8 PF03353.15 CEG41811.1 - 0.53 9.8 5.0 0.7 9.4 5.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PH_17 PF18012.1 CEG41812.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PH domain Pkinase PF00069.25 CEG41813.1 - 3e-76 256.3 0.0 3.5e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41813.1 - 1.1e-34 119.9 0.0 1.3e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG41813.1 - 8.5e-06 25.9 0.0 7e-05 22.9 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG41813.1 - 1.4e-05 24.2 0.0 4.5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG41813.1 - 0.011 15.1 0.1 0.039 13.3 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG41813.1 - 0.051 12.9 0.2 0.14 11.5 0.0 1.9 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 CEG41813.1 - 0.072 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF5009 PF16401.5 CEG41814.1 - 0.17 11.4 0.2 0.36 10.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) Rsbr_N PF08678.10 CEG41817.1 - 0.15 12.1 0.1 0.18 11.9 0.1 1.1 1 0 0 1 1 1 0 Rsbr N terminal CCT PF06203.14 CEG41818.1 - 5.5e-08 32.7 2.4 9.7e-08 31.9 2.4 1.4 1 0 0 1 1 1 1 CCT motif CBFB_NFYA PF02045.15 CEG41818.1 - 0.0085 16.7 1.0 0.021 15.5 1.0 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DED PF01335.21 CEG41818.1 - 0.068 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Death effector domain SHIPPO-rpt PF07004.12 CEG41819.1 - 6.9e-17 61.5 15.9 0.2 12.6 0.0 10.4 10 0 0 10 10 10 7 Sperm-tail PG-rich repeat ECR1_N PF14382.6 CEG41819.1 - 0.44 10.4 10.0 55 3.7 0.8 5.6 6 0 0 6 6 6 0 Exosome complex exonuclease RRP4 N-terminal region Metallophos PF00149.28 CEG41820.1 - 2e-31 110.1 0.0 3.6e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 CEG41820.1 - 0.007 16.8 0.2 0.035 14.5 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.29 CEG41821.1 - 0.0022 18.5 1.0 0.0051 17.3 0.1 2.1 2 0 0 2 2 2 1 PH domain Glycoprot_B_PH2 PF17417.2 CEG41821.1 - 3.8 7.9 5.9 3.6 8.0 1.5 3.0 3 1 1 4 4 4 0 Herpesvirus Glycoprotein B PH-like domain AhpC-TSA PF00578.21 CEG41822.1 - 7.6e-38 129.2 0.0 1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEG41822.1 - 3e-17 62.7 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEG41822.1 - 2.6e-14 52.8 0.1 4.4e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CEG41822.1 - 0.092 12.7 0.2 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC Beta_helix PF13229.6 CEG41824.1 - 3.8e-09 36.6 0.7 8.5e-09 35.4 0.7 1.5 1 0 0 1 1 1 1 Right handed beta helix region WW PF00397.26 CEG41824.1 - 5.8e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 WW domain NosD PF05048.13 CEG41824.1 - 0.0022 17.3 0.2 0.0042 16.4 0.2 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 CEG41824.1 - 0.0037 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 CEG41824.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 CEG41828.1 - 7.8e-41 140.2 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41828.1 - 2.4e-26 92.6 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG41828.1 - 0.0008 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG41828.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG41828.1 - 0.017 15.0 0.2 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG41828.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG41828.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase T5orf172 PF10544.9 CEG41829.1 - 0.13 12.8 0.4 0.17 12.5 0.4 1.4 1 1 0 1 1 1 0 T5orf172 domain DUF2238 PF09997.9 CEG41829.1 - 0.15 11.8 0.2 0.22 11.3 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) EF-hand_1 PF00036.32 CEG41832.1 - 0.02 14.4 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CEG41832.1 - 0.079 12.8 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 CEG41832.1 - 0.1 13.0 0.3 0.87 10.1 0.3 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CEG41832.1 - 0.17 11.9 0.1 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain PMG PF05287.12 CEG41832.1 - 5.1 7.1 8.1 43 4.1 0.0 2.7 3 0 0 3 3 3 0 PMG protein HHH_8 PF14716.6 CEG41833.1 - 6.3e-08 32.9 0.1 3.1e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain MAS20 PF02064.15 CEG41833.1 - 0.0012 19.0 0.3 0.0012 19.0 0.3 2.9 3 0 0 3 3 3 1 MAS20 protein import receptor DUF5434 PF17502.2 CEG41833.1 - 0.49 10.4 6.9 0.87 9.6 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5434) Nic96 PF04097.14 CEG41835.1 - 2.1e-121 406.4 0.0 2.7e-121 406.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 C2 PF00168.30 CEG41836.1 - 8.5e-13 48.5 0.1 1.8e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 CEG41836.1 - 1.6e-12 47.9 0.0 3.3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 CEG41836.1 - 7.1e-09 35.9 0.4 0.0024 18.2 0.2 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CEG41836.1 - 6.3e-07 29.1 0.0 0.0004 20.2 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 CEG41836.1 - 0.00017 21.9 0.0 0.00017 21.9 0.0 3.9 5 0 0 5 5 5 1 Pleckstrin homology domain CCDC53 PF10152.9 CEG41836.1 - 0.0042 17.5 19.1 0.063 13.7 15.6 3.5 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex zf-RanBP PF00641.18 CEG41836.1 - 0.0057 15.9 1.7 0.01 15.1 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 CEG41836.1 - 0.012 15.9 0.2 5.3 7.4 0.1 2.8 2 0 0 2 2 2 0 PDZ domain DUF4300 PF14133.6 CEG41836.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4300) Aminotran_1_2 PF00155.21 CEG41837.1 - 1.2e-35 123.3 0.0 1.5e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG41837.1 - 4.8e-06 25.8 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEG41837.1 - 5.8e-06 25.1 0.0 9.1e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 CEG41837.1 - 3.6e-05 22.7 0.2 0.0018 17.1 0.2 2.3 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 CEG41837.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEG41837.1 - 0.0054 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Spore_III_AB PF09548.10 CEG41837.1 - 0.11 12.5 1.9 0.24 11.5 1.9 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PFOR_II PF17147.4 CEG41837.1 - 0.12 12.7 0.0 6.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II CCDC-167 PF15188.6 CEG41837.1 - 0.46 10.8 3.5 1.1 9.7 3.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4164 PF13747.6 CEG41837.1 - 1 9.7 6.6 12 6.3 6.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) AICARFT_IMPCHas PF01808.18 CEG41838.1 - 3.4e-20 72.7 0.0 4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CEG41838.1 - 0.0035 17.5 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Exo_endo_phos PF03372.23 CEG41840.1 - 3.1e-06 26.9 0.0 5.4e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_1 PF00515.28 CEG41841.1 - 3.1e-19 67.9 3.5 0.00036 20.2 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEG41841.1 - 8.2e-19 67.0 3.9 0.00012 21.7 0.0 5.9 5 1 1 6 6 6 3 TPR repeat TPR_2 PF07719.17 CEG41841.1 - 2e-17 61.8 5.0 0.0034 17.4 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG41841.1 - 3.1e-17 61.8 6.0 0.00012 22.6 0.0 5.0 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG41841.1 - 9.9e-16 56.6 1.9 0.0074 16.4 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEG41841.1 - 5.1e-14 51.5 5.4 7.9e-06 25.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG41841.1 - 1.2e-12 48.2 5.9 1.8e-05 25.3 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG41841.1 - 7.1e-12 45.5 10.4 7.5e-07 29.4 1.3 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG41841.1 - 1.5e-10 41.4 7.8 4.3e-06 27.1 0.4 3.7 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG41841.1 - 7.6e-10 38.1 9.2 0.0062 16.5 0.1 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG41841.1 - 9.6e-08 32.2 5.0 0.12 13.0 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG41841.1 - 1.6e-05 24.6 1.3 2.4 8.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG41841.1 - 5.2e-05 22.6 3.0 0.15 11.2 0.2 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 CEG41841.1 - 0.00016 22.1 0.5 0.39 11.1 0.1 2.6 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_20 PF14561.6 CEG41841.1 - 0.00016 21.9 4.1 0.011 16.0 0.5 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG41841.1 - 0.0018 18.4 4.3 0.41 10.8 0.1 4.0 3 2 1 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 CEG41841.1 - 0.003 17.3 2.9 0.0097 15.6 2.4 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 CEG41841.1 - 0.0065 16.7 3.3 1.6 9.0 0.5 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CEG41841.1 - 0.037 14.1 4.7 49 4.1 0.1 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CEG41841.1 - 0.12 11.8 1.5 4.7 6.8 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.14 CEG41841.1 - 0.6 10.9 6.0 9.5 7.2 0.2 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat CDC45 PF02724.14 CEG41842.1 - 0.052 11.9 6.6 0.076 11.3 6.1 1.5 2 0 0 2 2 2 0 CDC45-like protein 4F5 PF04419.14 CEG41843.1 - 0.012 16.5 30.0 5.2 8.0 30.0 3.2 1 1 0 1 1 1 0 4F5 protein family EF-hand_1 PF00036.32 CEG41844.1 - 2.4e-14 51.7 0.3 0.00014 21.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CEG41844.1 - 8.1e-13 48.6 0.8 5.4e-07 30.0 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG41844.1 - 7.8e-11 41.0 0.5 0.032 14.1 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CEG41844.1 - 1.2e-10 41.1 0.2 0.00059 19.6 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG41844.1 - 1.4e-05 24.3 0.0 0.013 15.0 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CEG41844.1 - 0.0073 16.6 0.0 3.1 8.2 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CEG41844.1 - 0.0079 16.4 0.4 0.38 11.0 0.2 2.4 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 CEG41844.1 - 0.094 13.6 0.0 2.3 9.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.32 CEG41845.1 - 0.0002 22.1 0.7 0.15 13.0 0.0 3.2 2 1 0 2 2 2 2 WD domain, G-beta repeat Pro_isomerase PF00160.21 CEG41847.1 - 2.2e-50 171.0 0.1 6.6e-50 169.5 0.1 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transferase PF02458.15 CEG41847.1 - 1.1e-30 106.7 0.0 3.4e-30 105.1 0.0 1.7 1 1 1 2 2 2 1 Transferase family WD40 PF00400.32 CEG41847.1 - 2.3e-12 47.2 0.7 0.00059 20.6 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG41847.1 - 0.001 19.4 0.0 2 8.8 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 CEG41848.1 - 5e-12 46.7 0.0 1.4e-11 45.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG41848.1 - 0.02 15.1 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain MRAP PF15183.6 CEG41848.1 - 0.098 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PikAIV_N PF18605.1 CEG41849.1 - 0.66 9.6 3.6 1 9.0 3.6 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain RRM_1 PF00076.22 CEG41850.1 - 7.7e-18 64.1 0.2 4.2e-09 36.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG41850.1 - 0.002 17.7 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CEG41850.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) UBM PF14377.6 CEG41850.1 - 0.69 9.4 2.2 1.2 8.6 2.2 1.4 1 0 0 1 1 1 0 Ubiquitin binding region Acetyltransf_16 PF05301.11 CEG41851.1 - 4e-45 153.7 0.0 4.9e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 CEG41851.1 - 0.0011 19.3 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEG41851.1 - 0.0042 17.0 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG41851.1 - 0.014 15.6 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3103 PF11301.8 CEG41851.1 - 0.098 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Acetyltransf_4 PF13420.7 CEG41851.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5318 PF17249.2 CEG41853.1 - 0.045 13.5 0.5 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5318) DZR PF12773.7 CEG41853.1 - 0.13 12.3 21.8 0.77 9.8 7.6 3.4 2 1 1 3 3 3 0 Double zinc ribbon YacG PF03884.14 CEG41853.1 - 1.4 8.7 15.0 9 6.1 2.1 3.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zinc-ribbons_6 PF07191.12 CEG41853.1 - 2 8.5 16.7 0.12 12.4 4.4 3.1 2 1 1 3 3 3 0 zinc-ribbons zf-4CXXC_R1 PF10497.9 CEG41853.1 - 5.2 7.4 13.0 0.36 11.1 7.9 1.7 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Myosin_head PF00063.21 CEG41854.1 - 1.1e-190 635.3 0.0 2.2e-190 634.3 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Ank_4 PF13637.6 CEG41854.1 - 7.2e-13 48.8 1.7 4.7e-06 27.0 0.2 3.6 4 0 0 4 4 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41854.1 - 1.1e-09 38.8 1.2 0.00015 22.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG41854.1 - 6.7e-09 35.3 1.9 0.11 13.2 0.0 6.0 5 0 0 5 5 5 1 Ankyrin repeat Aida_C2 PF14186.6 CEG41854.1 - 1.2e-07 31.4 0.0 4.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal adhesion Ank_5 PF13857.6 CEG41854.1 - 7.1e-06 26.2 0.9 1.2 9.5 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.29 CEG41854.1 - 2e-05 25.0 0.0 5.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 PH domain AAA_16 PF13191.6 CEG41854.1 - 0.017 15.5 4.1 0.056 13.8 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain IQ PF00612.27 CEG41854.1 - 0.073 12.9 0.1 0.073 12.9 0.1 11.2 12 0 0 12 12 11 0 IQ calmodulin-binding motif RNA_helicase PF00910.22 CEG41854.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ank PF00023.30 CEG41854.1 - 1 9.9 5.3 22 5.7 0.1 3.8 4 1 0 4 4 3 0 Ankyrin repeat Zeta_toxin PF06414.12 CEG41854.1 - 1.6 8.0 8.3 0.03 13.6 0.4 2.2 3 0 0 3 3 3 0 Zeta toxin UBA PF00627.31 CEG41855.1 - 1.9e-13 50.0 0.4 3.8e-13 49.0 0.4 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 CEG41855.1 - 0.00056 19.6 0.2 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 CEG41855.1 - 0.00063 19.7 0.8 0.00089 19.2 0.8 1.3 1 1 0 1 1 1 1 Der1-like family UBA_4 PF14555.6 CEG41855.1 - 0.0017 18.1 1.3 0.0033 17.2 1.3 1.5 1 0 0 1 1 1 1 UBA-like domain tRNA-synt_1 PF00133.22 CEG41858.1 - 8.2e-213 708.0 0.0 1.1e-212 707.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEG41858.1 - 6.7e-24 84.6 0.1 2e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEG41858.1 - 3.8e-14 52.2 0.4 4.7e-05 22.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CEG41858.1 - 6.1e-07 29.1 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.27 CEG41859.1 - 1.6e-58 194.7 4.8 1.8e-22 79.0 0.2 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 CEG41860.1 - 5.8e-17 61.6 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PLATZ PF04640.14 CEG41861.1 - 0.0094 16.5 2.5 0.015 15.9 2.5 1.6 1 1 0 1 1 1 1 PLATZ transcription factor Mut7-C PF01927.16 CEG41861.1 - 0.027 14.6 0.3 0.036 14.2 0.3 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-FLZ PF04570.14 CEG41861.1 - 0.055 13.0 2.6 0.15 11.5 2.6 1.7 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-CHY PF05495.12 CEG41862.1 - 4.1e-17 62.4 21.4 4.1e-17 62.4 21.4 3.2 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 CEG41862.1 - 3.5e-11 43.3 6.0 3.5e-11 43.3 6.0 4.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG41862.1 - 2.8e-07 30.3 6.6 2.8e-07 30.3 6.6 5.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG41862.1 - 9.4e-07 28.6 4.4 9.4e-07 28.6 4.4 5.1 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG41862.1 - 9.6e-07 28.6 4.5 9.6e-07 28.6 4.5 5.3 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41862.1 - 2e-05 24.5 1.9 2e-05 24.5 1.9 4.4 5 3 0 5 5 5 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG41862.1 - 0.00013 21.8 2.5 0.00013 21.8 2.5 5.7 1 1 5 6 6 6 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CEG41862.1 - 0.00081 19.1 2.9 0.00081 19.1 2.9 4.6 5 0 0 5 5 5 1 RING-like zinc finger Phage_holin_3_1 PF05106.12 CEG41862.1 - 0.098 13.1 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Pkinase PF00069.25 CEG41864.1 - 5.6e-51 173.4 0.0 1.2e-50 172.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41864.1 - 3.2e-16 59.4 0.0 6.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CH_2 PF06294.11 CEG41864.1 - 6.8e-15 55.0 0.1 2.3e-14 53.2 0.1 2.0 1 0 0 1 1 1 1 CH-like domain in sperm protein APH PF01636.23 CEG41864.1 - 0.0058 16.6 1.4 0.02 14.8 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family COG2 PF06148.11 CEG41864.1 - 0.0087 16.2 0.6 0.0087 16.2 0.6 3.7 3 1 1 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 CEG41864.1 - 1.7 9.0 3.8 27 5.1 0.3 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPT PF03151.16 CEG41866.1 - 5.8e-40 137.4 29.1 7.1e-40 137.2 29.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEG41866.1 - 6.4e-11 42.6 33.9 5.1e-06 26.7 12.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEG41866.1 - 1.1e-07 31.3 26.0 1.7e-07 30.8 26.0 1.3 1 0 0 1 1 1 1 UAA transporter family Peptidase_S28 PF05577.12 CEG41867.1 - 4e-74 250.0 0.1 5.1e-74 249.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CEG41867.1 - 1.6e-05 23.8 0.0 2.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 CEG41867.1 - 0.0049 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold bZIP_2 PF07716.15 CEG41868.1 - 0.022 14.8 0.7 0.056 13.5 0.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CEG41868.1 - 0.022 14.9 1.8 0.022 14.9 1.8 1.6 2 0 0 2 2 2 0 bZIP transcription factor G-alpha PF00503.20 CEG41868.1 - 0.068 12.3 0.2 0.091 11.9 0.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit CorA PF01544.18 CEG41869.1 - 5.4e-45 154.0 1.0 8.3e-39 133.6 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 CEG41869.1 - 8.5e-05 22.9 0.1 0.00049 20.5 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG41869.1 - 0.0016 17.8 0.2 0.0041 16.6 0.2 1.8 1 0 0 1 1 1 1 EF hand ATP_bind_2 PF03668.15 CEG41869.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop ATPase protein family EF-hand_6 PF13405.6 CEG41869.1 - 0.0057 16.5 0.1 0.4 10.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CEG41869.1 - 0.0059 16.4 0.2 0.021 14.7 0.2 1.9 1 1 1 2 2 2 1 EF-hand domain pair mRNA_cap_C PF03919.15 CEG41869.1 - 0.071 13.7 0.3 0.19 12.4 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain SieB PF14163.6 CEG41869.1 - 0.23 11.0 1.4 0.5 9.8 1.4 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B DNA_repr_REX1B PF14966.6 CEG41871.1 - 0.098 13.3 1.2 0.23 12.1 1.2 1.7 1 0 0 1 1 1 0 DNA repair REX1-B zf-B_box PF00643.24 CEG41872.1 - 7.1e-05 22.9 3.3 0.00021 21.4 3.3 1.8 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CEG41872.1 - 0.0006 20.0 5.8 0.0018 18.4 5.8 1.8 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Ank_2 PF12796.7 CEG41873.1 - 2.9e-14 53.4 0.0 5.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG41873.1 - 4e-13 49.6 0.1 6.9e-05 23.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG41873.1 - 1.4e-12 47.6 1.4 2.5e-05 24.5 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG41873.1 - 3e-09 36.9 0.7 0.0023 18.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG41873.1 - 1.7e-08 34.0 0.1 0.063 13.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat TPR_1 PF00515.28 CEG41874.1 - 8.5e-11 41.2 8.7 0.0022 17.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG41874.1 - 1.6e-09 37.2 9.8 0.0055 16.7 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG41874.1 - 0.00013 22.2 5.9 0.13 12.6 1.6 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG41874.1 - 0.00037 21.1 4.3 0.00084 19.9 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG41874.1 - 0.003 17.6 6.4 0.65 10.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG41874.1 - 0.013 15.3 2.6 1.3 9.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 CEG41874.1 - 0.042 14.7 0.0 0.092 13.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.6 CEG41874.1 - 0.073 12.8 4.4 8.3 6.2 0.1 3.1 2 1 1 3 3 3 0 TPR repeat TPR_7 PF13176.6 CEG41874.1 - 0.08 13.0 4.0 8.1 6.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG41874.1 - 0.69 10.2 4.5 2.6 8.4 0.8 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IGPD PF00475.18 CEG41875.1 - 7.5e-58 194.9 1.6 1.4e-57 194.1 1.6 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 CEG41875.1 - 2e-19 70.4 0.0 6.9e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEG41875.1 - 3.4e-09 37.3 0.0 1e-07 32.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG41875.1 - 8.5e-09 35.4 0.0 2.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like UBX PF00789.20 CEG41878.1 - 8.3e-16 58.0 0.1 1.5e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 UBX domain RNase_PH PF01138.21 CEG41879.1 - 3.2e-17 63.3 0.9 1.2e-15 58.2 0.4 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG41879.1 - 5.4e-13 48.8 0.1 9.2e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1191 PF06697.12 CEG41879.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CD225 PF04505.12 CEG41882.1 - 0.15 12.2 4.7 0.4 10.8 0.2 2.3 1 1 0 2 2 2 0 Interferon-induced transmembrane protein FPN1 PF06963.12 CEG41883.1 - 3.9e-86 289.3 15.2 7e-86 288.5 15.2 1.4 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Herpes_UL49_5 PF05702.11 CEG41883.1 - 0.13 12.4 7.1 0.19 11.8 1.3 2.6 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Orbi_VP6 PF01516.16 CEG41884.1 - 0.084 12.4 2.2 0.13 11.7 2.2 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 MSC PF09402.10 CEG41884.1 - 4.4 6.7 7.6 0.25 10.8 1.6 1.8 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain rve PF00665.26 CEG41885.1 - 1.5e-18 67.1 0.0 3.4e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CEG41885.1 - 1.7e-05 24.5 0.1 3.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEG41885.1 - 0.0016 18.3 0.0 0.0055 16.6 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dicer_dimer PF03368.14 CEG41885.1 - 0.057 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Dicer dimerisation domain 5_nucleotid_C PF02872.18 CEG41887.1 - 0.081 13.1 1.2 0.28 11.4 0.2 2.1 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain Peptidase_S8 PF00082.22 CEG41892.1 - 1.6e-32 113.0 1.0 4.7e-23 81.9 0.5 2.6 1 1 1 2 2 2 2 Subtilase family Glyco_transf_22 PF03901.17 CEG41893.1 - 8.5e-81 272.3 31.6 1e-80 272.0 31.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase_Tyr PF07714.17 CEG41895.1 - 1.2e-62 211.5 0.0 1.9e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG41895.1 - 1e-54 185.7 0.0 1.6e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CEG41895.1 - 0.026 13.5 0.0 0.61 9.0 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain VPS9 PF02204.18 CEG41896.1 - 1.1e-14 54.5 0.0 1.4e-13 51.0 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 CEG41896.1 - 4.6e-07 29.8 0.6 1.5e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 PX domain DMA PF03474.14 CEG41896.1 - 0.02 14.5 1.2 0.47 10.1 0.0 3.1 2 0 0 2 2 2 0 DMRTA motif RVT_2 PF07727.14 CEG41896.1 - 0.026 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CUE PF02845.16 CEG41896.1 - 0.12 12.1 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 CUE domain rve PF00665.26 CEG41897.1 - 6.3e-14 52.2 0.0 9.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG41897.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CRAL_TRIO PF00650.20 CEG41901.1 - 6.4e-36 123.5 0.0 8.5e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG41901.1 - 0.00039 20.6 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3983 PF13137.6 CEG41901.1 - 0.14 12.0 1.0 0.29 11.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) N6-adenineMlase PF10237.9 CEG41902.1 - 4.7e-43 146.8 0.8 5.5e-43 146.6 0.8 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 CEG41902.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PTEN_C2 PF10409.9 CEG41903.1 - 4.2e-10 39.5 0.0 2.8e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CEG41903.1 - 1.7e-06 27.8 0.2 3.6e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG41903.1 - 2.4e-05 24.0 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEG41903.1 - 0.005 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CEG41903.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPn PF14671.6 CEG41903.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half TGase_elicitor PF16683.5 CEG41905.1 - 2.7e-110 368.6 0.0 3.2e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Chitin_synth_1 PF01644.17 CEG41908.1 - 1.7e-47 161.5 0.1 2.8e-47 160.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CEG41908.1 - 1.7e-25 89.6 0.7 2e-22 79.5 0.1 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEG41908.1 - 5.1e-10 39.6 3.1 5.1e-10 39.6 3.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEG41908.1 - 3.1e-07 30.5 0.0 6.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 CEG41908.1 - 1.7e-05 24.7 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal MIT PF04212.18 CEG41908.1 - 0.14 12.2 0.9 0.89 9.7 0.2 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RVT_1 PF00078.27 CEG41909.1 - 7.7e-18 64.8 0.0 1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEG41910.1 - 9.3e-30 103.1 0.4 1.4e-29 102.5 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG41910.1 - 1.5e-05 24.8 3.8 2.4e-05 24.2 3.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG41910.1 - 6.8e-05 22.6 3.7 0.0001 22.0 3.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEG41910.1 - 0.00024 21.0 1.3 0.00047 20.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEG41910.1 - 0.0062 16.2 1.8 0.014 15.1 1.5 1.7 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger GAS PF13851.6 CEG41913.1 - 1.4e-67 226.9 24.7 1.4e-67 226.9 24.7 3.8 2 2 2 4 4 4 1 Growth-arrest specific micro-tubule binding CENP-B_N PF04218.13 CEG41914.1 - 1.2e-09 37.6 0.1 2.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 CEG41914.1 - 3.2e-08 33.5 0.1 5.2e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 CEG41914.1 - 1.9e-07 30.7 0.1 2e-05 24.2 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 CEG41914.1 - 1.5e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 CEG41914.1 - 2.6e-05 24.3 0.9 0.0002 21.4 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 CEG41914.1 - 0.00032 20.7 0.2 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix DUF515 PF04415.12 CEG41914.1 - 0.047 12.1 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GPS2_interact PF15784.5 CEG41915.1 - 0.013 15.9 1.7 0.018 15.5 1.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Apt1 PF10351.9 CEG41915.1 - 0.042 12.7 1.0 0.05 12.5 1.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1827 PF08860.10 CEG41915.1 - 0.087 13.1 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) DUF3014 PF11219.8 CEG41916.1 - 0.033 14.5 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) UCR_hinge PF02320.16 CEG41917.1 - 0.12 12.7 7.3 0.17 12.1 3.2 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein RPAP1_C PF08620.10 CEG41920.1 - 3.6e-24 84.7 0.0 1.2e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CEG41920.1 - 5.1e-16 58.2 4.1 1.9e-15 56.3 4.1 2.1 1 0 0 1 1 1 1 RPAP1-like, N-terminal PhyH PF05721.13 CEG41921.1 - 5.9e-07 30.0 0.0 7.7e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) B277 PF17623.2 CEG41924.1 - 0.0014 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function MCLC PF05934.11 CEG41924.1 - 0.049 12.4 0.7 0.051 12.3 0.7 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3467 PF11950.8 CEG41928.1 - 0.075 13.2 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) bZIP_1 PF00170.21 CEG41929.1 - 4.3e-09 36.3 15.7 1.1e-08 35.0 15.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEG41929.1 - 7.1e-06 26.0 12.1 7.1e-06 26.0 12.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEG41929.1 - 0.0049 17.4 13.8 0.0049 17.4 13.8 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor FapA PF03961.13 CEG41929.1 - 0.034 12.7 7.1 0.056 12.0 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tnp_22_trimer PF17489.2 CEG41929.1 - 0.088 12.8 2.3 0.22 11.5 0.4 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain Fib_alpha PF08702.10 CEG41929.1 - 0.24 11.6 6.1 1.1 9.4 6.1 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 CEG41929.1 - 0.58 10.5 11.0 2.1 8.8 6.9 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain CAF1 PF04857.20 CEG41930.1 - 6.3e-67 226.0 0.0 9.7e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease S-methyl_trans PF02574.16 CEG41933.1 - 2e-46 158.9 0.0 2.5e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ank_4 PF13637.6 CEG41934.1 - 3.6e-08 33.8 0.0 0.00063 20.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Cyt-b5 PF00173.28 CEG41934.1 - 7.9e-08 32.3 0.0 0.00088 19.4 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Ank_5 PF13857.6 CEG41934.1 - 8.1e-06 26.0 0.1 1.7e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG41934.1 - 5.8e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG41934.1 - 0.00013 22.1 0.0 0.00038 20.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 CEG41934.1 - 0.004 17.5 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Peptidase_S74 PF13884.6 CEG41935.1 - 4e-12 46.3 0.0 6.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase Epiglycanin_TR PF05647.11 CEG41935.1 - 0.025 14.5 15.5 0.055 13.4 12.4 2.5 2 1 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like THF_DHG_CYH_C PF02882.19 CEG41936.1 - 2.4e-59 199.2 0.4 4e-59 198.5 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CEG41936.1 - 3.8e-27 94.9 0.1 6.8e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Pkinase PF00069.25 CEG41937.1 - 1.4e-68 231.2 0.0 2.1e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG41937.1 - 1.7e-32 112.7 0.0 2.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CEG41937.1 - 2.9e-09 36.9 0.5 7.3e-09 35.6 0.5 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CEG41937.1 - 5.1e-07 29.3 0.2 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 CEG41937.1 - 0.02 15.6 0.0 0.087 13.5 0.0 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 CEG41937.1 - 0.044 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEG41937.1 - 0.088 11.9 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CEG41937.1 - 0.15 11.7 0.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RVT_2 PF07727.14 CEG41938.1 - 6.7e-52 176.5 0.1 9.1e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mannosyl_trans3 PF11051.8 CEG41938.1 - 0.029 13.7 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Retrotran_gag_2 PF14223.6 CEG41939.1 - 4.1e-30 104.3 0.1 5e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG41939.1 - 4.7e-10 38.9 0.3 9.3e-10 37.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CEG41939.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UPF0147 PF03685.13 CEG41940.1 - 0.033 14.2 0.3 0.035 14.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) PH PF00169.29 CEG41942.1 - 0.013 16.0 0.3 0.041 14.4 0.0 1.9 2 1 0 2 2 2 0 PH domain DHHC PF01529.20 CEG41943.1 - 4.7e-30 104.4 12.1 4.7e-30 104.4 12.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 CEG41943.1 - 0.11 12.6 3.7 0.18 12.0 3.7 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger p25-alpha PF05517.12 CEG41946.1 - 4.2e-23 82.2 0.0 2.7e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 p25-alpha Tweety PF04906.13 CEG41947.1 - 7.2e-11 41.4 9.2 1.7e-10 40.2 9.2 1.5 1 1 0 1 1 1 1 Tweety zf-C2H2 PF00096.26 CEG41950.1 - 1.5e-16 59.8 26.8 6.9e-06 26.2 1.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG41950.1 - 1.7e-09 37.7 34.1 0.0037 18.0 0.7 5.1 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEG41950.1 - 5.4e-07 29.8 38.7 6.9e-06 26.3 2.4 6.5 6 0 0 6 6 6 3 Zinc-finger double domain FOXP-CC PF16159.5 CEG41950.1 - 0.00011 22.8 7.2 0.0019 18.8 0.0 4.0 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-TRAF PF02176.18 CEG41950.1 - 0.0018 18.9 9.9 0.021 15.5 1.5 2.3 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 CEG41950.1 - 0.013 15.8 7.7 1.4 9.3 0.8 3.5 1 1 2 3 3 3 0 C2H2-type zinc ribbon Ogr_Delta PF04606.12 CEG41950.1 - 0.017 15.1 2.1 1.3 9.1 0.1 3.4 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 CEG41950.1 - 0.018 14.8 15.0 0.11 12.2 0.4 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CEG41950.1 - 0.077 13.0 0.6 0.077 13.0 0.6 4.8 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEG41950.1 - 0.19 11.8 6.7 3.4 7.8 0.6 3.3 1 1 2 3 3 3 0 Aberrant zinc-finger GAGA PF09237.11 CEG41950.1 - 1.8 8.4 7.4 0.25 11.2 0.8 2.5 2 1 1 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.8 CEG41950.1 - 1.9 8.8 5.9 11 6.5 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 CEG41950.1 - 5.9 7.1 10.4 17 5.6 0.3 3.7 3 1 1 4 4 4 0 Zic proteins zinc finger domain PH PF00169.29 CEG41951.1 - 9.8e-05 22.8 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 PH domain HAD_2 PF13419.6 CEG41953.1 - 5.8e-10 39.5 0.1 4.8e-09 36.5 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG41953.1 - 2.5e-08 33.9 0.0 6.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEG41953.1 - 6.5e-07 29.9 0.0 1.6e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_26 PF13500.6 CEG41954.1 - 6.4e-35 120.8 0.0 1.1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 CEG41954.1 - 3.1e-08 33.3 0.0 7.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 CEG41954.1 - 0.077 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PAE PF03283.13 CEG41957.1 - 3.1e-11 43.0 0.2 4.5e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Pectinacetylesterase Mito_carr PF00153.27 CEG41959.1 - 1.5e-61 204.3 2.1 2.1e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RPA_C PF08784.11 CEG41960.1 - 9.3e-13 48.7 0.8 1.3e-12 48.3 0.1 1.6 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CEG41960.1 - 9.6e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 CEG41960.1 - 0.0005 19.9 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DUF5457 PF17540.2 CEG41960.1 - 0.062 13.4 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5457) MSP7_C PF12948.7 CEG41961.1 - 0.0071 17.0 1.3 0.076 13.7 0.3 2.2 2 0 0 2 2 2 1 MSP7-like protein C-terminal domain DPBB_1 PF03330.18 CEG41964.1 - 0.00095 19.4 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase TPPK_C PF12555.8 CEG41964.1 - 1.5 9.0 5.2 13 5.9 0.2 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DPBB_1 PF03330.18 CEG41965.1 - 2.2e-06 27.9 0.3 4.9e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEG41965.1 - 0.0026 17.6 2.0 0.0061 16.4 2.0 1.6 1 0 0 1 1 1 1 Barwin family DUF4064 PF13273.6 CEG41965.1 - 0.016 15.4 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Thg1C PF14413.6 CEG41965.1 - 0.17 12.0 4.2 0.44 10.7 2.0 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain DUF5308 PF17233.2 CEG41965.1 - 0.18 12.0 1.4 0.33 11.2 1.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5308) FYVE PF01363.21 CEG41966.1 - 7.7e-09 35.6 11.8 1.9e-08 34.3 11.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 CEG41966.1 - 2.9e-05 24.7 0.0 0.00015 22.4 0.0 2.2 3 0 0 3 3 3 1 GAF domain FYVE_2 PF02318.16 CEG41966.1 - 0.039 14.2 6.0 0.088 13.0 6.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 CEG41966.1 - 0.12 12.3 9.9 0.34 10.9 9.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG41966.1 - 0.12 12.2 12.7 0.33 10.8 12.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG41966.1 - 1.5 9.2 11.7 0.53 10.7 8.4 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 CEG41966.1 - 2.3 8.1 6.2 9.3 6.2 6.2 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG41966.1 - 7.7 6.6 9.8 5.6 7.1 5.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger TTL PF03133.15 CEG41967.1 - 2.9e-73 246.6 3.5 2.3e-72 243.6 0.0 2.9 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEG41967.1 - 3.2e-07 29.9 0.4 8.4e-05 21.9 0.0 3.7 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CEG41967.1 - 0.005 16.1 0.0 0.28 10.4 0.0 2.6 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp FYVE PF01363.21 CEG41969.1 - 0.0025 17.9 9.6 0.006 16.7 9.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger C1_4 PF07975.12 CEG41969.1 - 0.67 10.2 8.5 0.19 12.0 4.9 2.0 2 0 0 2 2 2 0 TFIIH C1-like domain DPBB_1 PF03330.18 CEG41970.1 - 4.1e-07 30.2 0.1 2e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 Lytic transglycolase DUF5305 PF17231.2 CEG41970.1 - 0.001 18.5 0.5 0.001 18.5 0.5 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5305) FixS PF03597.15 CEG41970.1 - 0.012 15.3 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Barwin PF00967.17 CEG41970.1 - 0.016 15.0 0.1 0.06 13.2 0.1 2.0 1 0 0 1 1 1 0 Barwin family DUF4366 PF14283.6 CEG41970.1 - 0.034 14.2 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) FAP PF07174.11 CEG41970.1 - 0.13 11.7 22.3 0.2 11.1 22.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PalH PF08733.10 CEG41971.1 - 0.075 12.0 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 FMO-like PF00743.19 CEG41973.1 - 1.3e-52 178.9 0.1 8.9e-46 156.4 0.2 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CEG41973.1 - 1.3e-21 77.2 0.0 1.9e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEG41973.1 - 1.8e-13 50.4 0.0 2.7e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG41973.1 - 7.3e-09 35.7 0.1 2e-08 34.3 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEG41973.1 - 7.5e-07 29.6 0.3 0.0052 17.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEG41973.1 - 1.8e-06 27.3 1.8 2.7e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CEG41973.1 - 4.9e-06 26.0 0.5 0.0018 17.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 CEG41973.1 - 8.8e-06 25.8 0.0 0.17 11.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 CEG41973.1 - 1.1e-05 25.2 5.2 0.026 14.1 2.2 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG41973.1 - 0.00018 20.3 2.1 0.00081 18.2 1.0 2.2 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 CEG41973.1 - 0.00056 19.3 0.0 0.0015 17.9 0.0 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CEG41973.1 - 0.00057 19.1 0.3 0.0063 15.6 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 CEG41973.1 - 0.0011 18.5 0.1 0.23 11.0 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 CEG41973.1 - 0.0035 16.8 0.2 0.0066 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CEG41973.1 - 0.0049 16.2 0.4 0.71 9.2 0.2 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEG41973.1 - 0.0092 15.6 0.8 0.81 9.2 0.3 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 CEG41973.1 - 0.014 14.5 0.1 1.6 7.7 0.3 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CEG41973.1 - 0.02 14.2 0.5 0.18 11.1 0.5 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CEG41973.1 - 0.03 14.7 0.0 3.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CEG41973.1 - 0.12 13.0 1.6 16 6.2 0.3 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.17 CEG41973.1 - 0.13 11.5 0.5 5 6.3 0.3 2.4 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 CEG41973.1 - 0.15 10.8 0.9 0.28 10.0 0.5 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 CEG41973.1 - 0.2 11.6 0.4 2 8.4 0.3 2.3 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 CEG41973.1 - 0.26 11.3 0.3 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CEG41973.1 - 0.34 10.8 0.9 33 4.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FYVE_2 PF02318.16 CEG41974.1 - 0.14 12.4 6.5 0.32 11.2 6.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG41974.1 - 0.61 10.3 8.9 1.4 9.1 8.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger RNA_pol_Rpb8 PF03870.15 CEG41975.1 - 1.5e-46 158.0 0.1 1.8e-46 157.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CEG41975.1 - 0.00074 19.6 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Ank_2 PF12796.7 CEG41976.1 - 2.1e-36 124.4 17.0 1.1e-12 48.3 1.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG41976.1 - 1.2e-27 95.9 17.8 2.9e-08 34.1 0.4 5.2 2 1 4 6 6 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CEG41976.1 - 8.3e-24 82.9 10.1 2.1e-06 27.9 0.4 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CEG41976.1 - 3.1e-20 70.1 10.0 0.00019 21.6 0.3 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CEG41976.1 - 3.8e-20 71.7 13.0 2e-07 31.1 0.4 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) PA PF02225.22 CEG41976.1 - 6.4e-19 67.8 0.0 1.8e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 PA domain HBM PF16591.5 CEG41976.1 - 0.021 14.3 1.9 0.048 13.1 1.9 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain Fib_alpha PF08702.10 CEG41976.1 - 0.14 12.4 5.1 0.18 12.0 3.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 CEG41976.1 - 0.15 12.4 3.2 0.38 11.1 3.2 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 CEG41976.1 - 0.17 11.8 1.5 0.42 10.5 1.5 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FlxA PF14282.6 CEG41976.1 - 0.17 11.9 7.7 0.43 10.6 7.7 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4521 PF15021.6 CEG41976.1 - 0.18 11.7 3.5 5.4 6.9 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4521) MIP-T3_C PF17749.1 CEG41976.1 - 0.19 11.7 6.0 0.12 12.3 2.5 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ApoLp-III PF07464.11 CEG41976.1 - 1.6 8.8 8.6 0.24 11.5 4.2 1.8 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) Peptidase_C12 PF01088.21 CEG41977.1 - 4.8e-59 199.7 0.0 5.4e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_23 PF13489.6 CEG41978.1 - 0.00058 19.7 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEG41978.1 - 0.0019 18.2 0.1 0.0033 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Na_H_antiporter PF03553.14 CEG41979.1 - 8.5e-37 127.0 2.2 8.5e-37 127.0 2.2 2.8 1 1 2 3 3 3 2 Na+/H+ antiporter family DcuC PF03606.15 CEG41979.1 - 0.012 14.1 25.6 0.047 12.2 11.7 3.0 2 2 1 3 3 3 0 C4-dicarboxylate anaerobic carrier CPBP PF02517.16 CEG41980.1 - 0.0012 19.2 7.8 0.004 17.5 7.5 2.3 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease YrzK PF17449.2 CEG41982.1 - 0.17 12.2 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized YrzK-like IQ PF00612.27 CEG41987.1 - 8.7e-06 25.1 24.1 0.016 15.0 0.8 5.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Kri1 PF05178.12 CEG41987.1 - 0.031 14.8 2.2 0.092 13.3 2.2 1.7 1 0 0 1 1 1 0 KRI1-like family XylR_N PF06505.11 CEG41987.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Activator of aromatic catabolism CS PF04969.16 CEG41988.1 - 3.2e-09 37.7 0.0 5.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 CS domain KASH_CCD PF14662.6 CEG41989.1 - 0.0047 16.8 4.7 0.0055 16.6 4.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF720 PF05302.11 CEG41989.1 - 0.0082 16.0 0.4 0.0089 15.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF720) TSC22 PF01166.18 CEG41989.1 - 0.0084 16.4 0.9 0.014 15.7 0.6 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 CEG41989.1 - 0.013 15.7 6.0 0.017 15.4 6.0 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 CEG41989.1 - 0.013 15.2 3.4 0.013 15.2 3.4 2.0 2 1 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 CEG41989.1 - 0.014 15.5 5.4 0.017 15.2 5.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 CEG41989.1 - 0.035 14.6 6.7 0.072 13.5 6.7 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.11 CEG41989.1 - 0.036 12.9 6.6 0.044 12.7 6.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 CEG41989.1 - 0.046 13.9 7.3 0.08 13.1 7.4 1.4 1 1 0 1 1 1 0 Tropomyosin like AnmK PF03702.14 CEG41989.1 - 0.053 12.6 0.2 0.061 12.4 0.2 1.0 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Mto2_bdg PF12808.7 CEG41989.1 - 0.11 12.9 6.1 0.32 11.3 1.1 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GIT_CC PF16559.5 CEG41989.1 - 0.11 12.3 2.7 0.23 11.4 2.7 1.6 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4250 PF14056.6 CEG41989.1 - 0.13 12.2 1.5 1.9 8.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) TolA_bind_tri PF16331.5 CEG41989.1 - 0.74 9.9 10.8 6.9 6.8 0.9 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation bZIP_2 PF07716.15 CEG41989.1 - 2.7 8.1 10.0 3.9 7.6 1.2 3.0 2 1 1 3 3 3 0 Basic region leucine zipper PikAIV_N PF18605.1 CEG41989.1 - 8.6 6.0 8.8 1.1 8.9 0.5 3.0 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HSF_DNA-bind PF00447.17 CEG41990.1 - 6e-24 84.5 0.2 1.8e-23 82.9 0.1 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Peroxidase_2 PF01328.17 CEG41992.1 - 2.8e-12 47.6 0.0 3.1e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 CTP_transf_1 PF01148.20 CEG41993.1 - 6.7e-07 29.3 12.1 6.7e-07 29.3 12.1 2.7 3 1 0 3 3 3 1 Cytidylyltransferase family AAA_5 PF07728.14 CEG41995.1 - 6.2e-26 91.0 0.0 1.3e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG41995.1 - 3.7e-05 24.2 1.0 0.0033 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_lid_7 PF17867.1 CEG41995.1 - 0.00028 21.0 1.7 0.00088 19.5 0.2 2.6 3 1 1 4 4 4 1 Midasin AAA lid domain Mg_chelatase PF01078.21 CEG41995.1 - 0.00037 19.9 0.0 0.00092 18.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEG41995.1 - 0.0005 20.4 1.4 0.033 14.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 CEG41995.1 - 0.0019 17.7 0.0 0.0049 16.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CEG41995.1 - 0.044 13.5 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CEG41995.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Cyclin PF08613.11 CEG41996.1 - 1.5e-08 35.2 0.1 2.3e-08 34.6 0.1 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEG41996.1 - 1.8e-08 34.2 0.2 3.3e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DAO PF01266.24 CEG41997.1 - 2e-42 146.0 0.2 5.7e-42 144.6 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEG41997.1 - 2.9e-09 36.6 0.0 0.00018 20.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG41997.1 - 1e-06 28.8 2.0 1.3e-06 28.5 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEG41997.1 - 6.5e-06 25.1 0.1 0.035 12.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 CEG41997.1 - 1.3e-05 24.5 0.1 0.00071 18.8 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CEG41997.1 - 0.00071 19.2 0.6 0.0013 18.4 0.6 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 CEG41997.1 - 0.0024 18.4 0.1 0.12 12.9 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEG41997.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 CEG41997.1 - 0.015 15.0 0.1 0.042 13.5 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CEG41997.1 - 0.029 13.6 0.2 0.068 12.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 CEG41997.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NUC194 PF08163.12 CEG41999.1 - 8e-49 166.6 2.7 1.6e-48 165.6 2.7 1.6 1 0 0 1 1 1 1 NUC194 domain PI3_PI4_kinase PF00454.27 CEG41999.1 - 1.3e-45 156.1 0.1 1.1e-44 153.1 0.0 2.6 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEG41999.1 - 3.8e-06 26.6 0.4 9.2e-06 25.4 0.4 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CEG42000.1 - 3.6e-11 42.3 9.2 0.63 10.5 0.0 9.0 10 0 0 10 10 9 4 HEAT repeat HEAT_EZ PF13513.6 CEG42000.1 - 4.9e-11 42.9 5.4 2.5e-09 37.4 0.0 5.2 6 0 0 6 6 5 1 HEAT-like repeat IBN_N PF03810.19 CEG42000.1 - 8e-08 32.1 0.5 3e-06 27.0 0.1 2.8 2 1 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 CEG42000.1 - 4.5e-05 23.4 2.4 4.4 7.5 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CEG42000.1 - 8.4e-05 23.1 0.2 1.2 9.7 0.1 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 CEG42000.1 - 0.00052 19.2 10.9 0.29 10.2 0.1 4.2 4 1 0 4 4 4 3 Interferon-related developmental regulator (IFRD) Chromo PF00385.24 CEG42000.1 - 0.00081 19.3 0.2 0.0018 18.1 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ecm29 PF13001.7 CEG42000.1 - 0.0051 15.6 1.1 2.2 6.9 0.0 2.9 3 0 0 3 3 3 2 Proteasome stabiliser Xpo1 PF08389.12 CEG42000.1 - 0.021 14.9 0.3 0.39 10.8 0.0 3.3 3 1 0 3 3 3 0 Exportin 1-like protein FAA_hydrolase_N PF09298.11 CEG42000.1 - 0.037 14.2 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal MMS19_C PF12460.8 CEG42000.1 - 0.073 12.2 1.4 19 4.2 0.0 4.2 3 2 2 5 5 5 0 RNAPII transcription regulator C-terminal Dpoe2NT PF12213.8 CEG42000.1 - 0.092 13.0 0.5 0.99 9.7 0.0 2.8 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal DUF577 PF04510.12 CEG42000.1 - 0.22 11.4 2.0 0.34 10.8 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF577) p450 PF00067.22 CEG42001.1 - 4.6e-70 236.6 0.0 5.9e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APP_N PF02177.16 CEG42001.1 - 0.079 13.3 0.0 9.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Amyloid A4 N-terminal heparin-binding IFNGR1 PF07140.11 CEG42002.1 - 1.2 9.2 5.2 27 4.9 0.9 3.0 3 0 0 3 3 3 0 Interferon gamma receptor (IFNGR1) DUF4674 PF15719.5 CEG42010.1 - 0.022 14.8 3.1 0.028 14.5 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Trehalose_PPase PF02358.16 CEG42011.1 - 1.1e-53 181.8 0.0 2e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase TauD PF02668.16 CEG42011.1 - 3.1e-21 76.4 0.1 6.5e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CEG42011.1 - 1.9e-12 47.6 0.5 4.7e-12 46.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Phosphodiest PF01663.22 CEG42011.1 - 0.0041 16.8 0.4 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2339 PF10101.9 CEG42011.1 - 0.73 8.3 14.7 1.1 7.8 14.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) RibD_C PF01872.17 CEG42012.1 - 1.3e-31 110.0 0.0 1.6e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain SepZ PF06066.11 CEG42012.1 - 0.11 12.7 0.3 0.27 11.4 0.3 1.6 1 0 0 1 1 1 0 SepZ Ribonucleas_3_3 PF14622.6 CEG42013.1 - 4.6e-42 143.2 0.1 7.1e-20 71.5 0.0 3.4 3 0 0 3 3 3 3 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CEG42013.1 - 1.1e-33 116.0 0.4 2e-16 60.5 0.1 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribosomal_L32p PF01783.23 CEG42013.1 - 0.0004 20.6 2.2 0.0013 18.9 2.2 1.9 1 0 0 1 1 1 1 Ribosomal L32p protein family LEF-8 PF04941.12 CEG42013.1 - 0.087 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) Torus PF16131.5 CEG42014.1 - 6.8e-09 36.4 0.1 1.5e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CEG42014.1 - 3.4e-06 26.9 2.9 3.4e-06 26.9 2.9 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 CEG42014.1 - 7.5e-06 25.7 2.9 7.5e-06 25.7 2.9 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG42014.1 - 0.00017 21.3 3.1 0.0004 20.1 3.1 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG42014.1 - 0.029 14.9 1.4 0.07 13.6 1.4 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GCV_T PF01571.21 CEG42015.1 - 3.8e-12 46.1 0.1 5.8e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PI31_Prot_N PF11566.8 CEG42016.1 - 1.1e-09 38.3 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 CEG42016.1 - 2.9e-06 28.4 5.7 2.9e-06 28.4 5.7 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator TPR_1 PF00515.28 CEG42017.1 - 7.6e-10 38.2 0.1 0.015 15.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG42017.1 - 1.1e-08 34.5 0.0 0.017 15.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42017.1 - 1.6e-06 28.3 0.2 0.0051 17.1 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG42017.1 - 0.00013 21.5 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 CEG42017.1 - 0.00024 20.9 0.0 2.2 8.5 0.1 4.1 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG42017.1 - 0.00093 19.2 0.2 0.23 11.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG42017.1 - 0.0011 18.7 0.5 0.083 12.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG42017.1 - 0.0024 18.5 1.7 0.46 11.2 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Agenet PF05641.12 CEG42017.1 - 0.0094 16.4 0.1 0.034 14.6 0.1 1.9 1 0 0 1 1 1 1 Agenet domain DUF1027 PF06265.11 CEG42017.1 - 0.16 12.0 0.2 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) TPR_14 PF13428.6 CEG42017.1 - 0.27 12.2 2.6 3.8 8.6 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG42017.1 - 1.4 9.7 4.8 29 5.6 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat RecG_N PF17190.4 CEG42017.1 - 3 8.6 7.0 0.87 10.4 1.0 3.0 3 1 0 3 3 2 0 RecG N-terminal helical domain AroM PF07302.11 CEG42018.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 AroM protein GlutR_dimer PF00745.20 CEG42018.1 - 0.025 15.0 1.1 0.63 10.5 0.0 2.7 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phage_CRI PF05144.14 CEG42018.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage replication protein CRI CPL PF08144.11 CEG42018.1 - 0.069 13.5 0.5 0.47 10.8 0.1 2.3 2 1 0 2 2 2 0 CPL (NUC119) domain Arylsulfotrans PF05935.11 CEG42018.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Trehalase PF01204.18 CEG42019.1 - 7e-136 454.0 0.0 8.3e-136 453.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 CEG42019.1 - 0.014 14.2 0.2 9.7 4.8 0.0 3.1 3 0 0 3 3 3 0 Glycosyl hydrolase family 63 C-terminal domain PH PF00169.29 CEG42022.1 - 6.7e-06 26.6 0.1 1.3e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 PH domain Cast PF10174.9 CEG42022.1 - 0.0014 17.0 1.3 0.0022 16.3 1.3 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF1664 PF07889.12 CEG42022.1 - 0.089 12.8 3.9 0.49 10.4 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 CEG42022.1 - 0.09 12.6 4.2 0.7 9.7 4.1 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF16 PF01519.16 CEG42022.1 - 3.6 8.1 5.5 21 5.7 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 CDC50 PF03381.15 CEG42023.1 - 5.2e-83 278.8 0.1 9.3e-83 278.0 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pkinase PF00069.25 CEG42023.1 - 1.2e-67 228.1 0.0 1.6e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42023.1 - 2.5e-30 105.6 0.0 3.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG42023.1 - 0.05 13.5 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 CEG42024.1 - 7.6e-10 38.5 0.0 0.00072 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 CEG42025.1 - 6.4e-34 117.9 0.8 9.5e-32 110.8 0.2 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEG42025.1 - 4.3e-06 26.3 1.5 6.9e-06 25.6 0.8 1.7 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CEG42025.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RCC1 PF00415.18 CEG42026.1 - 9.3e-47 157.4 15.7 2.5e-11 44.0 0.0 7.6 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG42026.1 - 1.1e-20 72.9 38.0 1.4e-08 34.3 1.1 7.5 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat WW PF00397.26 CEG42026.1 - 3e-14 52.8 8.7 2.2e-07 30.8 0.1 3.8 3 0 0 3 3 3 2 WW domain IQ PF00612.27 CEG42026.1 - 7.5e-06 25.3 31.4 0.013 15.2 0.3 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif SAP PF02037.27 CEG42026.1 - 0.014 15.2 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 SAP domain Vps39_2 PF10367.9 CEG42027.1 - 5.7e-24 84.7 0.1 3.9e-23 82.0 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CEG42027.1 - 1.3e-15 57.5 0.2 4.7e-15 55.8 0.2 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 GAF PF01590.26 CEG42029.1 - 7.7e-05 23.3 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain GalKase_gal_bdg PF10509.9 CEG42031.1 - 5.6e-19 67.4 0.1 1.3e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CEG42031.1 - 2e-16 60.1 0.3 8.4e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CEG42031.1 - 2.5e-12 46.8 1.6 2.5e-12 46.8 1.6 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain HNH_2 PF13391.6 CEG42031.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Retrotran_gag_2 PF14223.6 CEG42032.1 - 4.5e-22 78.2 0.2 5.4e-22 77.9 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Smac_DIABLO PF09057.10 CEG42032.1 - 0.029 13.7 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases DNA_pol_B_2 PF03175.13 CEG42033.1 - 0.0012 17.8 0.2 0.0025 16.7 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Cornifin PF02389.15 CEG42033.1 - 0.0017 18.6 33.8 0.0017 18.6 33.8 3.8 2 2 0 3 3 3 2 Cornifin (SPRR) family V_ATPase_I PF01496.19 CEG42033.1 - 0.62 7.9 9.2 0.11 10.5 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PTPRCAP PF15713.5 CEG42033.1 - 0.68 10.2 14.2 2.1 8.6 0.5 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated 5_3_exonuc_N PF02739.16 CEG42035.1 - 4.1e-33 114.5 0.2 5.7e-33 114.1 0.2 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 CEG42035.1 - 3.6e-12 46.7 0.0 7.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold NYN_YacP PF05991.11 CEG42035.1 - 0.013 15.4 0.1 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 YacP-like NYN domain Homeodomain PF00046.29 CEG42036.1 - 7.3e-28 96.2 10.3 1.1e-08 34.8 0.1 4.2 4 0 0 4 4 4 3 Homeodomain PHD PF00628.29 CEG42036.1 - 8.4e-06 25.6 12.0 1.6e-05 24.7 12.0 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 CEG42036.1 - 0.0023 18.2 1.8 0.005 17.1 1.8 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 CEG42036.1 - 0.004 17.0 6.8 0.0088 15.9 6.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Homeobox_KN PF05920.11 CEG42036.1 - 0.015 15.2 1.3 8.5 6.4 0.1 4.0 3 0 0 3 3 3 0 Homeobox KN domain Homez PF11569.8 CEG42036.1 - 0.026 14.0 1.2 17 4.9 0.0 4.0 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez DUF3226 PF11536.8 CEG42036.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Prok-RING_1 PF14446.6 CEG42036.1 - 0.27 11.2 6.6 0.77 9.7 6.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 CEG42036.1 - 0.48 10.1 6.5 0.93 9.2 6.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 CEG42036.1 - 0.7 9.5 6.4 1.4 8.5 6.4 1.5 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 CEG42036.1 - 0.76 9.9 10.2 2.4 8.3 10.2 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 CEG42036.1 - 0.81 9.6 10.2 2.2 8.2 10.2 1.8 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-4CXXC_R1 PF10497.9 CEG42036.1 - 1.7 8.9 9.4 4.4 7.6 9.4 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 CEG42036.1 - 4.7 7.6 13.4 8.6 6.8 13.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CEG42036.1 - 8.2 6.5 12.5 17 5.5 12.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Tetraspanin PF00335.20 CEG42042.1 - 3.4e-12 46.6 10.7 4.7e-12 46.1 10.7 1.2 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 CEG42042.1 - 0.0038 17.3 6.9 0.0062 16.6 1.5 2.6 2 0 0 2 2 2 1 CD20-like family TMEM51 PF15345.6 CEG42042.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 PRKCSH-like PF12999.7 CEG42046.1 - 7.6e-34 117.0 4.9 7.6e-34 117.0 4.9 2.2 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CEG42046.1 - 5.4e-27 94.4 1.9 1.3e-26 93.2 0.4 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 CEG42046.1 - 0.0045 16.9 1.1 0.05 13.5 0.0 2.5 1 1 1 2 2 2 1 Autophagy-related protein 27 NdhN PF11909.8 CEG42046.1 - 0.031 13.9 0.5 0.059 13.1 0.5 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Zip PF02535.22 CEG42046.1 - 0.35 10.1 2.4 0.48 9.6 2.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ldl_recept_a PF00057.18 CEG42046.1 - 0.4 11.0 20.1 1.9 8.8 4.4 3.5 2 1 1 3 3 3 0 Low-density lipoprotein receptor domain class A Presenilin PF01080.17 CEG42046.1 - 0.91 8.2 3.4 1.1 7.9 3.4 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CEG42046.1 - 1.2 7.4 11.7 2.2 6.5 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Phage_holin_6_1 PF09682.10 CEG42046.1 - 1.7 9.1 6.9 0.13 12.7 1.7 1.8 2 0 0 2 2 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) RNA_pol_Rpc4 PF05132.14 CEG42046.1 - 2.6 8.4 5.7 5.2 7.5 5.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PRKCSH PF07915.13 CEG42046.1 - 2.7 9.1 8.2 0.39 11.8 0.5 2.8 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein DUF5006 PF16397.5 CEG42049.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) ATP-synt PF00231.19 CEG42051.1 - 7.4e-77 258.8 4.2 8.4e-77 258.6 4.2 1.0 1 0 0 1 1 1 1 ATP synthase Mito_carr PF00153.27 CEG42052.1 - 1.2e-64 214.2 0.8 1.7e-20 72.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CEG42052.1 - 3.8e-13 49.7 0.9 9.8e-08 32.3 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG42052.1 - 8.4e-08 31.6 2.2 0.0054 16.6 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CEG42052.1 - 1.3e-07 30.6 0.7 0.037 13.6 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CEG42052.1 - 9.5e-05 22.2 0.2 0.011 15.6 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG42052.1 - 0.0011 18.3 1.5 0.017 14.6 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CEG42052.1 - 0.0056 17.0 0.1 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain Pkinase PF00069.25 CEG42054.1 - 1.2e-39 136.3 0.0 1.8e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42054.1 - 4.2e-21 75.4 0.0 7.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42054.1 - 1.9e-07 30.7 0.0 1.4e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CEG42054.1 - 0.00037 20.5 0.0 0.26 11.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG42054.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L17 PF01196.19 CEG42055.1 - 5.2e-34 117.0 0.2 7e-34 116.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 ABATE PF07336.11 CEG42055.1 - 0.017 15.8 0.6 0.028 15.1 0.6 1.4 1 0 0 1 1 1 0 Putative stress-induced transcription regulator DUF2767 PF10965.8 CEG42055.1 - 0.11 12.5 0.8 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) Yippee-Mis18 PF03226.14 CEG42056.1 - 1.6e-22 79.7 0.1 6e-22 77.8 0.1 2.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FHA PF00498.26 CEG42056.1 - 0.0021 18.4 0.3 0.017 15.5 0.1 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CEG42056.1 - 0.11 12.9 0.0 0.53 10.6 0.1 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain CD36 PF01130.21 CEG42057.1 - 9.2e-40 136.5 0.0 1.1e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 CD36 family Pkinase PF00069.25 CEG42058.1 - 2.4e-19 69.8 0.6 1.7e-18 67.0 0.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42058.1 - 7.9e-08 31.9 0.4 1.5e-05 24.4 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.18 CEG42061.1 - 7e-35 119.4 4.5 1.7e-11 44.6 0.4 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG42061.1 - 6.1e-27 92.8 5.4 3.4e-10 39.4 0.3 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 CEG42061.1 - 0.24 11.4 4.1 11 6.1 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG42061.1 - 0.38 10.8 2.6 17 5.5 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Imm49 PF15575.6 CEG42063.1 - 0.0047 16.7 1.2 1.7 8.3 0.0 3.5 4 0 0 4 4 4 2 Immunity protein 49 Uds1 PF15456.6 CEG42063.1 - 1.8 8.8 5.6 1.8 8.8 0.5 2.8 2 0 0 2 2 2 0 Up-regulated During Septation BT1 PF03092.16 CEG42064.1 - 4.2e-09 35.2 19.6 4.8e-09 35.0 2.2 2.7 3 1 0 3 3 3 2 BT1 family BT1 PF03092.16 CEG42066.1 - 1.7e-08 33.1 18.4 1.9e-07 29.7 5.1 2.4 2 0 0 2 2 2 2 BT1 family BT1 PF03092.16 CEG42068.1 - 1.5e-09 36.6 6.6 1.5e-09 36.6 6.6 2.7 2 1 1 3 3 3 1 BT1 family gag_pre-integrs PF13976.6 CEG42071.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 GAG-pre-integrase domain PapD_N PF00345.20 CEG42071.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain CompInhib_SCIN PF11546.8 CEG42072.1 - 0.075 13.1 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN cpYpsA PF12694.7 CEG42073.1 - 0.094 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Ferric_reduct PF01794.19 CEG42074.1 - 4.6e-13 49.4 6.8 4.6e-13 49.4 6.8 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEG42074.1 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEG42074.1 - 5.3e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CEG42074.1 - 0.00052 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1681 PF07933.14 CEG42076.1 - 1.4e-52 177.4 0.0 1.7e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) NUC PF18510.1 CEG42076.1 - 0.019 15.4 1.0 0.037 14.5 1.0 1.5 1 1 0 1 1 1 0 Nuclease domain Myosin_head PF00063.21 CEG42077.1 - 2.8e-228 759.5 0.2 3.7e-228 759.1 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 CEG42077.1 - 4e-12 46.1 0.3 9.1e-12 45.0 0.3 1.5 1 0 0 1 1 1 1 PX domain FtsK_SpoIIIE PF01580.18 CEG42077.1 - 0.025 13.9 1.0 3 7.1 0.1 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family POTRA_2 PF08479.11 CEG42077.1 - 0.032 14.0 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 POTRA domain, ShlB-type Myosin_N PF02736.19 CEG42077.1 - 0.065 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_18 PF13238.6 CEG42077.1 - 0.066 13.8 0.4 0.44 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEG42077.1 - 0.094 13.0 1.3 0.34 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG42077.1 - 0.25 11.7 0.0 0.25 11.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain IQ PF00612.27 CEG42077.1 - 0.56 10.1 9.1 1.1 9.2 0.3 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif DUF5010 PF16402.5 CEG42081.1 - 0.0058 15.5 1.7 7.5 5.3 0.0 3.8 3 1 0 4 4 4 3 Domain of unknown function (DUF5010) CCDC-167 PF15188.6 CEG42083.1 - 0.0093 16.3 6.4 0.0093 16.3 6.4 16.6 6 3 7 13 13 13 2 Coiled-coil domain-containing protein 167 Sugar_tr PF00083.24 CEG42084.1 - 4.5e-29 101.6 10.6 5.5e-29 101.3 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG42084.1 - 1e-10 41.1 11.3 1.3e-10 40.8 11.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.13 CEG42084.1 - 1.1 8.6 8.7 1.6 8.1 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3792 PF12670.7 CEG42084.1 - 2.8 8.1 20.0 4.3 7.5 7.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 CEG42085.1 - 1.2e-17 63.9 7.9 1.6e-17 63.6 7.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG42085.1 - 6.7e-13 48.3 11.5 8.1e-13 48.0 11.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CEG42085.1 - 1e-05 24.3 0.2 1.3e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 CEG42085.1 - 4.7e-05 22.0 0.4 4.8e-05 22.0 0.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MHCassoc_trimer PF08831.10 CEG42085.1 - 0.027 14.5 0.1 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain SYS1 PF09801.9 CEG42086.1 - 3.4e-30 105.1 4.9 3.9e-30 104.9 4.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Rad60-SLD_2 PF13881.6 CEG42088.1 - 2.3e-21 76.0 0.0 2.6e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEG42088.1 - 0.0018 18.8 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF5393 PF17371.2 CEG42088.1 - 0.038 12.1 0.1 0.041 12.0 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5393) zf-RING_2 PF13639.6 CEG42089.1 - 1.1e-05 25.7 8.1 2.8e-05 24.3 8.1 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CEG42089.1 - 0.00053 20.1 4.1 0.0017 18.5 4.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CEG42089.1 - 0.0017 18.6 5.1 0.0047 17.2 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEG42089.1 - 0.002 18.2 3.2 0.0053 16.8 3.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CEG42089.1 - 0.0028 17.8 5.6 0.0065 16.6 5.6 1.7 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 CEG42089.1 - 0.0049 16.7 1.6 0.011 15.6 1.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HEPN_LA2681 PF18733.1 CEG42089.1 - 0.0072 15.7 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 LA2681-like HEPN Zn_ribbon_17 PF17120.5 CEG42089.1 - 0.028 14.0 2.5 0.066 12.8 2.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CEG42089.1 - 0.043 14.1 5.8 0.13 12.6 5.8 1.9 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 CEG42089.1 - 0.045 13.6 10.0 0.098 12.5 10.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG42089.1 - 0.12 12.3 8.5 0.29 11.0 8.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lig_C PF18330.1 CEG42089.1 - 0.15 12.1 0.4 3.5 7.7 0.1 2.9 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region Zf_RING PF16744.5 CEG42089.1 - 0.29 11.3 2.1 0.9 9.7 2.1 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 CEG42089.1 - 0.31 11.0 5.3 0.74 9.8 5.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 CEG42089.1 - 9.3 6.2 10.0 21 5.1 10.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_2 PF07724.14 CEG42090.1 - 2.8e-41 141.5 0.6 4.3e-33 114.8 0.2 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEG42090.1 - 2.8e-16 60.1 0.8 2.4e-06 28.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CEG42090.1 - 7.6e-08 32.3 2.5 1.7e-07 31.2 0.2 2.6 2 1 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 CEG42090.1 - 2.8e-07 30.9 0.0 5e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEG42090.1 - 4.6e-07 29.9 0.3 5e-05 23.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CEG42090.1 - 7e-06 25.3 0.3 0.00036 19.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_33 PF13671.6 CEG42090.1 - 3.2e-05 24.1 0.0 9.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG42090.1 - 3.4e-05 23.2 0.1 0.00011 21.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CEG42090.1 - 8.1e-05 23.1 0.2 0.00047 20.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CEG42090.1 - 0.00018 21.0 0.1 0.0027 17.1 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CEG42090.1 - 0.00027 20.3 0.2 0.00027 20.3 0.2 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 CEG42090.1 - 0.00028 20.7 0.8 0.03 14.1 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CEG42090.1 - 0.00059 19.6 0.0 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CEG42090.1 - 0.00073 19.6 0.1 2.2 8.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 CEG42090.1 - 0.00087 18.5 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.6 CEG42090.1 - 0.00099 19.7 0.1 0.0036 17.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain ATP-synt_ab PF00006.25 CEG42090.1 - 0.0013 18.4 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 CEG42090.1 - 0.0021 18.3 0.2 0.0083 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG42090.1 - 0.0023 18.5 0.0 0.006 17.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Spore_IV_A PF09547.10 CEG42090.1 - 0.0034 16.4 2.2 0.072 12.0 0.8 2.5 2 1 0 2 2 2 1 Stage IV sporulation protein A (spore_IV_A) T2SSE PF00437.20 CEG42090.1 - 0.0093 15.1 0.5 0.037 13.1 0.1 2.1 2 1 1 3 3 3 1 Type II/IV secretion system protein ATPase_2 PF01637.18 CEG42090.1 - 0.016 15.1 2.1 0.55 10.1 1.9 2.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea tRNA_lig_kinase PF08303.11 CEG42090.1 - 0.022 14.9 1.4 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 tRNA ligase kinase domain PduV-EutP PF10662.9 CEG42090.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CEG42090.1 - 0.028 13.8 0.3 0.06 12.8 0.0 1.9 2 0 0 2 2 1 0 Bacterial TniB protein Rad17 PF03215.15 CEG42090.1 - 0.04 13.8 0.0 0.095 12.6 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 CEG42090.1 - 0.062 13.0 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CEG42090.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CEG42090.1 - 0.067 13.1 0.0 2.2 8.1 0.0 3.0 2 1 1 3 3 3 0 NACHT domain DEAD PF00270.29 CEG42090.1 - 0.069 12.9 0.1 0.27 11.0 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase TsaE PF02367.17 CEG42090.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CEG42090.1 - 0.12 12.1 0.2 0.79 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CEG42090.1 - 0.13 12.4 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 CEG42090.1 - 0.29 11.6 6.2 13 6.2 0.2 3.7 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 CEG42090.1 - 0.54 10.6 4.5 1.8 8.9 1.8 2.9 2 1 0 2 2 2 0 AAA domain Las1 PF04031.13 CEG42091.1 - 2.4e-45 154.4 6.5 2.4e-45 154.4 6.5 1.9 2 0 0 2 2 2 1 Las1-like DUF4530 PF15039.6 CEG42091.1 - 6 7.0 6.5 13 6.0 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4530) PX PF00787.24 CEG42092.1 - 1.9e-09 37.5 0.1 4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 PX domain DNA_ligase_A_M PF01068.21 CEG42092.1 - 0.045 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Mo25 PF08569.11 CEG42094.1 - 7.5e-75 252.3 4.9 1.2e-74 251.6 4.9 1.4 1 1 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 CEG42094.1 - 0.025 13.9 5.1 0.02 14.2 2.8 1.7 1 1 1 2 2 2 0 V-ATPase subunit H DUF4518 PF15008.6 CEG42094.1 - 0.034 13.3 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) CPSF_A PF03178.15 CEG42095.1 - 9.3e-61 205.9 0.0 4.5e-60 203.7 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 CEG42095.1 - 8.3e-30 103.9 0.0 3.3e-28 98.6 0.0 2.5 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term IF-2B PF01008.17 CEG42097.1 - 9.5e-61 205.5 0.1 2.2e-60 204.3 0.1 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family HEAT_2 PF13646.6 CEG42097.1 - 0.063 13.7 0.3 0.2 12.1 0.2 1.8 2 0 0 2 2 2 0 HEAT repeats PLU-1 PF08429.11 CEG42100.1 - 0.09 11.9 4.1 0.22 10.7 4.1 1.7 1 1 0 1 1 1 0 PLU-1-like protein bZIP_1 PF00170.21 CEG42100.1 - 0.21 11.7 11.1 6.3 7.0 6.6 2.8 2 0 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 CEG42103.1 - 0.092 12.1 0.8 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FGGY_N PF00370.21 CEG42105.1 - 1.1e-73 247.9 0.1 1.7e-73 247.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEG42105.1 - 2.6e-60 203.6 0.2 3.9e-60 203.0 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CEG42105.1 - 0.1 12.1 0.1 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family AAA PF00004.29 CEG42107.1 - 5.2e-34 117.5 0.0 9.7e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG42107.1 - 6.6e-07 29.2 0.0 1.9e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG42107.1 - 3.2e-05 24.0 0.0 0.0003 20.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEG42107.1 - 7.4e-05 22.9 0.0 0.00024 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG42107.1 - 0.0002 21.8 0.0 0.0028 18.0 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG42107.1 - 0.00041 20.6 0.1 0.23 11.8 0.0 3.2 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CEG42107.1 - 0.0022 18.2 0.0 0.016 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CEG42107.1 - 0.0075 16.8 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEG42107.1 - 0.017 15.4 0.0 0.058 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEG42107.1 - 0.033 13.9 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CEG42107.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CEG42107.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CEG42107.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CEG42107.1 - 0.17 11.2 0.1 0.73 9.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TPR_2 PF07719.17 CEG42108.1 - 3.9e-05 23.4 0.6 17 5.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG42108.1 - 6.2e-05 22.8 0.6 3.2 8.0 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42108.1 - 0.0026 18.0 6.3 1.3 9.4 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG42108.1 - 0.0089 16.5 2.9 14 6.3 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG42108.1 - 0.03 14.5 0.0 18 5.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 CEG42108.1 - 0.042 14.1 0.1 27 5.3 0.0 4.2 4 0 0 4 4 4 0 PPR repeat ANAPC3 PF12895.7 CEG42108.1 - 0.065 13.5 3.1 5.6 7.3 0.3 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 YqhG PF11079.8 CEG42108.1 - 0.13 11.2 0.2 0.25 10.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function PPR_2 PF13041.6 CEG42108.1 - 0.16 12.2 0.3 17 5.7 0.0 2.9 2 0 0 2 2 2 0 PPR repeat family LPD34 PF18852.1 CEG42109.1 - 0.061 12.9 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Large polyvalent protein associated domain 34 DEDD_Tnp_IS110 PF01548.17 CEG42110.1 - 0.036 14.0 0.8 0.077 12.9 0.1 2.0 2 0 0 2 2 2 0 Transposase APG6_N PF17675.1 CEG42110.1 - 3.2 8.3 10.9 15 6.1 0.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 CEG42110.1 - 8 6.5 7.9 2.7 8.0 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Elicitin PF00964.17 CEG42113.1 - 1e-06 28.7 0.2 2.7e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Elicitin zf-CCCH PF00642.24 CEG42115.1 - 1.2e-11 44.1 8.5 1.7e-07 31.0 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG42115.1 - 1.3e-11 44.2 15.7 1.5e-05 24.9 3.0 2.6 2 0 0 2 2 2 2 Zinc finger domain CTD_bind PF04818.13 CEG42115.1 - 5.4e-11 43.2 0.0 1e-10 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-CCCH_4 PF18044.1 CEG42115.1 - 9.5e-11 41.2 11.4 2.2e-05 24.1 1.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG42115.1 - 0.00043 20.6 11.6 0.00086 19.7 3.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG42115.1 - 0.72 10.6 11.9 0.14 12.9 0.6 3.1 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 CEG42115.1 - 1.3 9.3 3.8 6 7.1 0.4 2.4 1 1 1 2 2 2 0 Zinc-finger containing family LisH PF08513.11 CEG42118.1 - 1.7e-06 27.8 2.9 2.3e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 LisH EF-hand_1 PF00036.32 CEG42120.1 - 1.4e-12 46.2 1.4 2.8e-05 23.4 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG42120.1 - 9.8e-11 42.0 0.4 9.8e-11 42.0 0.4 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG42120.1 - 5.8e-09 35.2 0.1 0.0029 17.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG42120.1 - 1.1e-06 27.9 0.3 0.0061 16.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG42120.1 - 9.1e-05 22.2 1.1 0.039 13.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair FUSC PF04632.12 CEG42120.1 - 0.012 14.2 3.8 0.087 11.3 0.6 2.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Phasin_2 PF09361.10 CEG42120.1 - 0.038 14.2 0.6 0.098 12.9 0.6 1.6 1 0 0 1 1 1 0 Phasin protein ArAE_1 PF06081.11 CEG42120.1 - 1.7 8.8 8.7 0.16 12.1 0.6 2.9 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 RNB PF00773.19 CEG42122.1 - 1e-92 311.0 0.0 1.5e-92 310.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEG42122.1 - 2.2e-21 75.6 0.0 5.2e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 CEG42122.1 - 7.8e-19 67.4 0.5 2.3e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 CEG42122.1 - 4.2e-11 42.8 0.0 8.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CEG42122.1 - 2.2e-06 27.8 0.1 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Cold shock domain TEBP_beta PF07404.11 CEG42124.1 - 0.034 13.5 0.0 0.036 13.4 0.0 1.0 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Methyltransf_16 PF10294.9 CEG42125.1 - 8.9e-11 41.8 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG42125.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4457 PF14652.6 CEG42126.1 - 5.7e-176 584.5 0.3 1.9e-117 392.2 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 CEG42126.1 - 0.0023 18.0 0.0 6.6 6.8 0.0 4.5 5 1 0 5 5 5 2 Sad1 / UNC-like C-terminal UCR_Fe-S_N PF10399.9 CEG42127.1 - 0.044 13.1 0.5 0.67 9.3 0.0 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal FYVE_2 PF02318.16 CEG42127.1 - 0.05 13.8 6.1 0.19 12.0 6.1 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG42127.1 - 0.41 10.8 7.9 1.1 9.4 7.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger Paired_CXXCH_1 PF09699.10 CEG42127.1 - 8.6 6.2 13.2 1.1e+02 2.7 13.2 2.4 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1230 PF06799.11 CEG42128.1 - 0.17 12.0 2.4 0.25 11.5 2.4 1.2 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 Pro_isomerase PF00160.21 CEG42130.1 - 4.4e-46 157.0 0.0 6.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4709 PF15821.5 CEG42130.1 - 0.055 13.8 1.9 0.082 13.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) DUF1690 PF07956.11 CEG42130.1 - 0.13 12.6 3.5 0.19 12.2 3.5 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) PIP5K PF01504.18 CEG42131.1 - 2.1e-69 233.8 0.0 5.8e-69 232.3 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG42131.1 - 1.1e-07 31.4 9.6 3.8e-07 29.6 9.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 CEG42131.1 - 4.3e-05 23.0 6.7 4.3e-05 23.0 6.7 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 CEG42131.1 - 0.0018 17.5 4.1 0.0018 17.5 4.1 1.9 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor PX PF00787.24 CEG42132.1 - 0.048 13.7 1.4 0.69 9.9 1.0 2.7 2 1 0 2 2 2 0 PX domain DUF1484 PF07363.11 CEG42133.1 - 3.4 8.7 6.4 1.4 10.0 0.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1484) DUF4404 PF14357.6 CEG42133.1 - 7.6 7.2 18.0 52 4.6 0.7 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF4407 PF14362.6 CEG42133.1 - 8.8 5.6 14.1 12 5.1 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ephrin_rec_like PF07699.13 CEG42134.1 - 3.7e-43 145.1 102.4 1.8e-07 30.8 2.3 12.2 4 3 10 14 14 14 13 Putative ephrin-receptor like LRR_8 PF13855.6 CEG42134.1 - 1.4e-08 34.4 22.2 3e-05 23.7 4.4 3.8 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 CEG42134.1 - 2.1e-07 31.1 25.2 0.017 15.5 4.5 5.5 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG42134.1 - 1.6e-06 27.8 23.9 2.4 9.1 1.7 8.8 9 0 0 9 9 9 3 Leucine Rich Repeat TNFR_c6 PF00020.18 CEG42134.1 - 0.0011 19.3 85.4 0.56 10.7 1.6 12.8 7 3 9 16 16 16 10 TNFR/NGFR cysteine-rich region VSP PF03302.13 CEG42134.1 - 0.014 14.3 73.7 0.085 11.7 10.0 5.3 2 1 3 5 5 5 0 Giardia variant-specific surface protein LRR_6 PF13516.6 CEG42134.1 - 1.6 9.0 19.3 7.6 6.9 1.2 6.5 8 0 0 8 8 8 0 Leucine Rich repeat TPX2_importin PF12214.8 CEG42135.1 - 3.5e-11 43.6 59.4 1.3e-05 25.4 1.5 5.8 4 1 1 5 5 5 5 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 CEG42135.1 - 3.2e-09 36.9 21.6 3.2e-09 36.9 21.6 4.5 5 0 0 5 5 5 2 Targeting protein for Xklp2 (TPX2) DUF3870 PF12986.7 CEG42135.1 - 0.1 12.8 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Lsm_interact PF05391.11 CEG42140.1 - 0.1 12.1 1.2 0.22 11.1 1.2 1.6 1 0 0 1 1 1 0 Lsm interaction motif Trypsin PF00089.26 CEG42144.1 - 4.9e-07 29.8 0.0 6.2e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin CAP PF00188.26 CEG42149.1 - 1.4e-20 74.4 2.7 2.6e-20 73.5 2.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF346 PF03984.13 CEG42149.1 - 0.11 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) CAP PF00188.26 CEG42151.1 - 8.5e-15 55.7 0.3 1.3e-14 55.1 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family 7TM_GPCR_Srbc PF10316.9 CEG42151.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc DUF3833 PF12915.7 CEG42152.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3833) Peptidase_S74 PF13884.6 CEG42153.1 - 0.00056 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase CENP-K PF11802.8 CEG42154.1 - 1.6 8.2 8.2 2.6 7.6 8.2 1.2 1 0 0 1 1 1 0 Centromere-associated protein K TIMELESS PF04821.14 CEG42156.1 - 2.4e-54 184.5 7.3 2.4e-54 184.5 7.3 2.2 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 CEG42156.1 - 0.00019 20.7 0.2 0.00019 20.7 0.2 2.6 2 0 0 2 2 2 1 Timeless protein C terminal region CRA PF06589.11 CEG42156.1 - 0.043 13.9 0.5 0.043 13.9 0.5 2.3 3 0 0 3 3 3 0 Circumsporozoite-related antigen (CRA) FAM176 PF14851.6 CEG42156.1 - 7.9 6.1 7.2 1 9.1 0.4 2.8 3 0 0 3 3 3 0 FAM176 family PDZ PF00595.24 CEG42157.1 - 5e-06 26.8 0.0 7.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG42157.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CEG42157.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 PDZ domain GMC_oxred_N PF00732.19 CEG42160.1 - 3.1e-100 335.4 0.0 4.7e-100 334.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEG42160.1 - 7.9e-40 136.7 0.0 1.3e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEG42160.1 - 5.1e-06 25.8 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CEG42160.1 - 2.3e-05 23.6 0.0 3.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CEG42160.1 - 9.2e-05 22.2 0.0 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEG42160.1 - 0.00039 19.8 0.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG42160.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEG42160.1 - 0.001 18.4 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEG42160.1 - 0.0041 17.6 0.0 1.6 9.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEG42160.1 - 0.0089 15.3 0.2 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CEG42160.1 - 0.016 14.5 0.1 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG42160.1 - 0.034 12.8 0.0 0.28 9.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein HLH PF00010.26 CEG42162.1 - 1.1e-08 34.9 2.6 2.3e-08 33.9 2.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CEG42162.1 - 1.4e-06 28.2 0.1 3.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CEG42162.1 - 0.00015 22.0 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold MRPL52 PF18699.1 CEG42162.1 - 0.0038 17.4 0.3 0.0038 17.4 0.3 2.8 2 1 1 3 3 3 1 Mitoribosomal protein mL52 Mtc PF03820.17 CEG42162.1 - 0.016 14.2 0.2 0.032 13.3 0.2 1.4 1 0 0 1 1 1 0 Tricarboxylate carrier PAS_4 PF08448.10 CEG42162.1 - 0.021 15.1 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 CEG42162.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_5 PF07310.13 CEG42162.1 - 0.13 12.1 0.8 0.84 9.4 0.1 2.4 1 1 2 3 3 3 0 PAS domain GMC_oxred_N PF00732.19 CEG42164.1 - 6.3e-96 321.2 0.0 8.2e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEG42164.1 - 4.7e-34 118.0 0.0 8.5e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEG42164.1 - 3.8e-06 26.2 0.0 0.065 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 CEG42164.1 - 1.4e-05 24.5 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEG42164.1 - 3e-05 23.3 0.0 4.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CEG42164.1 - 0.00055 20.1 0.1 0.0019 18.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEG42164.1 - 0.00059 19.1 0.0 0.0039 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEG42164.1 - 0.00083 19.0 0.0 0.015 14.9 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CEG42164.1 - 0.01 16.4 0.0 0.66 10.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG42164.1 - 0.011 14.4 0.0 0.069 11.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CEG42164.1 - 0.015 14.5 0.1 0.039 13.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 CEG42164.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 CEG42164.1 - 0.018 14.7 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 CEG42164.1 - 0.042 13.2 0.1 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase IFT81_CH PF18383.1 CEG42166.1 - 4.6e-27 94.7 2.3 7.9e-27 94.0 0.0 2.6 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain NPV_P10 PF05531.12 CEG42166.1 - 6 7.4 15.9 4.2 7.9 0.4 4.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CEG42166.1 - 8.6 6.7 41.4 0.027 14.8 2.9 6.7 4 2 4 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HsbA PF12296.8 CEG42166.1 - 9.3 6.7 8.5 2.9 8.3 0.2 3.5 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Pkinase PF00069.25 CEG42167.1 - 8.8e-69 231.8 0.0 1.1e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42167.1 - 1.5e-48 165.4 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42167.1 - 2.1e-05 24.0 0.1 0.00027 20.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG42167.1 - 2.2e-05 23.5 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG42167.1 - 0.055 13.4 3.0 0.072 13.0 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC1 PF03109.16 CEG42167.1 - 0.17 12.0 0.2 0.86 9.8 0.0 2.2 3 0 0 3 3 3 0 ABC1 family 2-oxoacid_dh PF00198.23 CEG42168.1 - 5.6e-66 222.3 0.0 7.2e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pro_CA PF00484.19 CEG42169.1 - 0.025 14.9 0.3 0.059 13.7 0.2 1.5 1 1 1 2 2 2 0 Carbonic anhydrase CSG2 PF16965.5 CEG42169.1 - 0.026 13.5 0.5 0.026 13.5 0.5 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Pantoate_ligase PF02569.15 CEG42169.1 - 0.042 13.1 0.2 0.043 13.0 0.2 1.1 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DAGAT PF03982.13 CEG42171.1 - 7.9e-44 149.8 0.0 9.2e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Cullin PF00888.22 CEG42172.1 - 7.3e-138 460.9 4.3 7.3e-138 460.9 4.3 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CEG42172.1 - 2.2e-18 66.0 2.3 2.2e-18 66.0 2.3 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 CEG42172.1 - 0.0077 16.8 0.0 0.042 14.4 0.0 2.3 1 0 0 1 1 1 1 Bacteriophage replication protein O TTL PF03133.15 CEG42174.1 - 7.9e-73 245.1 1.1 7.2e-57 192.8 0.0 2.7 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEG42174.1 - 8.9e-06 25.1 0.1 0.00076 18.8 0.0 3.1 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CEG42174.1 - 0.0021 17.4 0.0 0.011 14.9 0.0 2.1 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp rve_2 PF13333.6 CEG42174.1 - 0.043 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain MA3 PF02847.17 CEG42174.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 MA3 domain p450 PF00067.22 CEG42175.1 - 8.6e-45 153.3 0.2 8.3e-26 90.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 GutM PF06923.11 CEG42177.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) AKAP28 PF14469.6 CEG42178.1 - 1.3e-05 24.9 0.0 3.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 28 kDa A-kinase anchor EF-hand_7 PF13499.6 CEG42178.1 - 0.00024 21.5 0.0 2.5 8.6 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG42178.1 - 0.02 14.4 0.0 6.7 6.5 0.0 3.1 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 CEG42178.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pur_ac_phosph_N PF16656.5 CEG42178.1 - 0.14 12.7 0.2 0.3 11.7 0.2 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain LRR_6 PF13516.6 CEG42179.1 - 1e-05 25.2 6.9 0.081 13.0 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat Herpes_BLRF2 PF05812.12 CEG42179.1 - 0.82 9.8 6.8 0.26 11.4 1.2 3.0 3 2 1 4 4 4 0 Herpesvirus BLRF2 protein DUF573 PF04504.14 CEG42180.1 - 0.054 14.1 0.8 3.4 8.4 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Phage_SSB PF16773.5 CEG42181.1 - 0.037 14.1 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein UPF0054 PF02130.17 CEG42182.1 - 9.2e-31 106.3 0.0 1.1e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Mito_carr PF00153.27 CEG42183.1 - 6.7e-18 64.4 9.2 1.8e-08 34.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PAE PF03283.13 CEG42184.1 - 1.6e-09 37.4 0.0 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase GSHPx PF00255.19 CEG42185.1 - 3.6e-29 100.5 0.1 8.4e-29 99.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione peroxidase PH PF00169.29 CEG42185.1 - 1.2e-06 28.9 0.1 0.026 15.0 0.0 2.5 2 0 0 2 2 2 2 PH domain AhpC-TSA PF00578.21 CEG42185.1 - 6.9e-06 26.0 0.1 2.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family PH_11 PF15413.6 CEG42185.1 - 0.00061 20.2 2.3 0.42 11.0 0.2 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Redoxin PF08534.10 CEG42185.1 - 0.00096 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Redoxin PH_13 PF16652.5 CEG42185.1 - 0.0031 17.3 2.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Gln-synt_N PF03951.19 CEG42185.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Copine PF07002.16 CEG42187.1 - 3.4e-66 222.8 0.0 4.8e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CEG42187.1 - 3.6e-25 88.2 0.0 5.3e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CEG42187.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus WRC PF08879.10 CEG42188.1 - 0.0084 15.8 1.0 0.019 14.7 0.3 1.9 2 0 0 2 2 2 1 WRC Brr6_like_C_C PF10104.9 CEG42188.1 - 0.089 12.6 0.2 0.1 12.4 0.2 1.0 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_hydro_72 PF03198.14 CEG42190.1 - 3e-48 164.7 0.0 4.1e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Rhamnogal_lyase PF06045.11 CEG42190.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family Macoilin PF09726.9 CEG42194.1 - 0.25 9.9 6.2 0.43 9.1 6.2 1.3 1 0 0 1 1 1 0 Macoilin family DnaJ PF00226.31 CEG42195.1 - 3.3e-23 81.6 1.7 3.3e-23 81.6 1.7 3.3 4 0 0 4 4 4 1 DnaJ domain TPR_2 PF07719.17 CEG42195.1 - 1.3e-15 56.1 8.9 0.38 11.0 0.0 10.2 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG42195.1 - 3.5e-13 49.8 9.9 0.013 16.0 1.9 6.4 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG42195.1 - 3.7e-10 39.2 4.5 1.3 9.0 0.0 9.0 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG42195.1 - 5.7e-10 39.2 3.3 1.2e-05 25.3 0.0 4.7 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG42195.1 - 4.2e-09 35.9 3.4 5.5 7.5 0.0 8.8 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG42195.1 - 4.3e-08 32.7 2.1 0.34 10.6 0.0 6.5 7 2 2 9 9 9 2 TPR repeat TPR_14 PF13428.6 CEG42195.1 - 2.3e-07 31.1 10.4 6.9 7.8 0.7 8.1 3 3 6 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG42195.1 - 4.8e-06 26.0 10.2 0.0025 17.1 2.7 4.4 1 1 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG42195.1 - 1.4e-05 25.6 8.5 9 7.0 0.1 6.4 4 3 3 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG42195.1 - 3.7e-05 23.9 8.4 0.054 13.7 0.0 4.6 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG42195.1 - 4.7e-05 23.8 6.5 2.3 9.0 0.0 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG42195.1 - 0.00033 20.8 1.0 9.1 6.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG42195.1 - 0.00051 19.9 4.0 35 4.7 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 CEG42195.1 - 0.00066 20.1 10.9 0.25 11.8 0.0 4.5 3 1 1 4 4 4 1 Bacterial transcriptional activator domain DUF3856 PF12968.7 CEG42195.1 - 0.027 14.5 2.4 0.42 10.7 0.6 3.5 3 2 2 5 5 4 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 CEG42195.1 - 0.047 13.2 1.8 3.4 7.2 0.0 3.1 2 0 0 2 2 2 0 SHNi-TPR Alkyl_sulf_dimr PF14863.6 CEG42195.1 - 0.2 12.1 6.8 2.8 8.4 0.0 3.9 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 CEG42195.1 - 0.46 10.9 6.5 5.9 7.3 0.1 4.3 2 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42195.1 - 2.1 8.7 19.3 0.36 11.1 2.7 4.9 5 3 0 5 5 4 0 Tetratricopeptide repeat ICMT PF04140.14 CEG42199.1 - 2.8e-29 101.4 0.7 4.7e-29 100.7 0.7 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEG42199.1 - 3.7e-11 43.4 0.3 6.5e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CEG42199.1 - 0.0013 18.3 0.3 0.0016 18.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 CEG42199.1 - 0.0089 15.6 2.1 0.012 15.1 2.2 1.3 1 1 0 1 1 1 1 NnrU protein CK2S PF15011.6 CEG42200.1 - 2.3e-08 34.1 2.8 3.2e-08 33.6 2.8 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate DDE_1 PF03184.19 CEG42201.1 - 2e-10 40.6 0.1 1.5e-09 37.8 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease Ank_2 PF12796.7 CEG42203.1 - 4.7e-16 59.1 0.9 5.7e-09 36.4 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG42203.1 - 2.7e-10 40.3 2.2 0.002 18.4 0.1 4.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG42203.1 - 3.1e-09 37.2 2.9 0.00095 19.7 0.2 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG42203.1 - 3.5e-07 30.0 1.4 0.13 12.9 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 CEG42203.1 - 0.034 14.6 2.4 63 4.3 0.0 4.6 2 2 2 4 4 4 0 Ankyrin repeat CARD PF00619.21 CEG42204.1 - 2 8.5 11.9 5.3 7.1 0.2 4.6 5 0 0 5 5 5 0 Caspase recruitment domain HD PF01966.22 CEG42205.1 - 1.1e-11 45.0 0.3 2.3e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 CEG42205.1 - 0.18 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 HDOD domain Retrotran_gag_3 PF14244.6 CEG42208.1 - 0.05 13.4 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PH PF00169.29 CEG42209.1 - 5.4e-21 75.1 0.1 9.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CEG42209.1 - 1.1e-05 25.8 8.9 0.083 13.3 2.8 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CEG42209.1 - 0.0041 17.4 2.9 0.81 10.0 1.0 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain RecG_N PF17190.4 CEG42210.1 - 0.19 12.5 5.2 0.83 10.4 0.1 3.8 4 0 0 4 4 4 0 RecG N-terminal helical domain RXLR PF16810.5 CEG42210.1 - 0.44 11.0 4.8 1.4 9.3 0.1 3.0 3 1 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity DUF1772 PF08592.11 CEG42211.1 - 9.6e-14 51.9 0.5 1.7e-13 51.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Kazal_2 PF07648.15 CEG42211.1 - 0.15 12.2 0.9 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Sld5 PF05916.11 CEG42211.1 - 1.1 9.8 5.0 0.67 10.4 0.1 2.5 2 1 0 2 2 2 0 GINS complex protein Kinesin PF00225.23 CEG42212.1 - 1.2e-111 372.8 0.2 1.2e-111 372.8 0.2 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEG42212.1 - 1.6e-24 86.5 1.9 4.3e-24 85.2 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Cyto_heme_lyase PF01265.17 CEG42213.1 - 7.6e-51 173.4 7.7 1.9e-49 168.8 7.7 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase WYL_2 PF10902.8 CEG42214.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold Spo7_2_N PF15407.6 CEG42215.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 VPS9 PF02204.18 CEG42216.1 - 1.5e-15 57.3 0.3 4.4e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain B56 PF01603.20 CEG42217.1 - 5e-149 496.8 3.6 3.6e-140 467.6 0.2 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Zip PF02535.22 CEG42217.1 - 1.7e-38 132.7 17.2 2.4e-38 132.2 17.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter ATP-synt_ab PF00006.25 CEG42218.1 - 7.2e-54 182.7 0.5 1.3e-52 178.6 0.5 2.2 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEG42218.1 - 7.6e-24 84.0 0.6 2e-23 82.7 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 CEG42218.1 - 0.041 14.2 1.0 0.1 12.9 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG42218.1 - 0.13 12.7 0.1 0.71 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S18 PF01084.20 CEG42219.1 - 1.1e-17 63.9 0.9 1.8e-17 63.3 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 FTR1 PF03239.14 CEG42220.1 - 0.07 12.3 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Iron permease FTR1 family MCM PF00493.23 CEG42221.1 - 2.4e-99 331.0 0.2 5.9e-99 329.7 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CEG42221.1 - 1.8e-36 124.8 0.9 3.2e-36 124.0 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEG42221.1 - 2.2e-28 98.5 0.5 6.8e-28 96.9 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEG42221.1 - 3.7e-12 46.8 0.1 1.1e-11 45.2 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEG42221.1 - 5.3e-05 22.7 0.0 0.00027 20.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG42221.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG42221.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) His_Phos_1 PF00300.22 CEG42222.1 - 3.7e-33 114.8 0.0 1.2e-26 93.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Proteasome PF00227.26 CEG42230.1 - 7.6e-45 152.7 0.0 9.7e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Apt1 PF10351.9 CEG42233.1 - 4.1e-23 82.0 0.5 6.4e-22 78.1 0.1 2.8 2 1 0 2 2 2 1 Golgi-body localisation protein domain IncD PF17628.2 CEG42234.1 - 1.2 9.0 4.7 2.3 8.0 4.4 1.6 1 1 1 2 2 2 0 Inclusion membrane protein D Ribosomal_L30_N PF08079.12 CEG42235.1 - 2.2e-24 85.5 12.7 2.2e-24 85.5 12.7 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CEG42235.1 - 2.5e-23 81.7 2.9 5.4e-23 80.6 2.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Laminin_G_3 PF13385.6 CEG42236.1 - 3.1e-06 27.4 0.3 3.2e-05 24.1 0.1 2.6 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily ANAPC4_WD40 PF12894.7 CEG42236.1 - 0.00053 20.2 0.0 0.0084 16.4 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG42236.1 - 0.007 17.2 0.2 0.052 14.4 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG42237.1 - 0.00098 19.4 0.0 5.8 7.3 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG42237.1 - 0.001 19.9 0.6 4 8.5 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec7 PF01369.20 CEG42238.1 - 5.6e-42 143.5 0.0 7.8e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Pkinase PF00069.25 CEG42241.1 - 3.2e-61 207.0 0.0 5e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42241.1 - 1.3e-23 83.6 0.0 2.3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Epimerase PF01370.21 CEG42241.1 - 9.4e-21 74.4 0.0 1.7e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEG42241.1 - 9.2e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CEG42241.1 - 1.8e-11 43.7 0.1 3.3e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEG42241.1 - 2.1e-09 37.5 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CEG42241.1 - 1.4e-06 27.5 0.1 3.4e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family WW PF00397.26 CEG42241.1 - 0.00031 20.8 0.4 0.00071 19.6 0.4 1.6 1 0 0 1 1 1 1 WW domain Polysacc_synt_2 PF02719.15 CEG42241.1 - 0.00033 19.9 0.0 0.0009 18.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CEG42241.1 - 0.0031 17.0 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CEG42241.1 - 0.004 16.7 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Haspin_kinase PF12330.8 CEG42241.1 - 0.052 12.5 0.2 0.095 11.6 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG42241.1 - 0.059 12.7 0.7 0.13 11.6 0.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF896 PF05979.12 CEG42242.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) 2OG-FeII_Oxy_2 PF13532.6 CEG42244.1 - 1.5e-44 152.6 0.0 2.6e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3048_C PF17479.2 CEG42244.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain PTCB-BRCT PF12738.7 CEG42246.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CEG42246.1 - 0.0013 19.1 0.1 0.0062 16.9 0.1 1.9 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEG42246.1 - 0.0026 18.1 0.0 0.0039 17.6 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain FYVE PF01363.21 CEG42247.1 - 9.5e-09 35.3 15.1 2.4e-08 34.0 15.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 CEG42247.1 - 0.00016 22.3 0.0 0.00055 20.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEG42247.1 - 0.00031 21.0 0.0 0.00064 20.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 CEG42247.1 - 0.0012 19.1 5.6 0.005 17.0 5.6 2.2 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 CEG42247.1 - 0.043 14.2 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 GAF domain Prok-RING_2 PF14445.6 CEG42247.1 - 0.19 11.9 5.6 0.67 10.2 5.6 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Nbl1_Borealin_N PF10444.9 CEG42248.1 - 8.8e-07 28.5 0.8 4e-06 26.4 0.2 2.4 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 CEG42248.1 - 9.1e-07 28.9 1.9 4.3e-06 26.7 1.6 2.3 1 1 0 1 1 1 1 Cell division cycle-associated protein 8 CC2D2AN-C2 PF15625.6 CEG42249.1 - 1.9e-08 34.3 1.0 4.6e-08 33.0 0.3 2.1 2 0 0 2 2 2 1 CC2D2A N-terminal C2 domain Myb_DNA-binding PF00249.31 CEG42250.1 - 1e-10 41.6 0.1 3.2e-08 33.6 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG42250.1 - 5.6e-06 26.2 1.4 9.6e-05 22.2 0.1 3.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CEG42250.1 - 0.0024 18.1 1.0 0.024 14.9 0.2 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain AlphaC_C PF17480.2 CEG42250.1 - 0.33 11.0 9.6 0.61 10.1 2.9 3.4 3 0 0 3 3 3 0 AlphaC C-terminal DUF4030 PF13222.6 CEG42253.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) Ank_2 PF12796.7 CEG42256.1 - 4.5e-42 142.5 0.1 1.2e-14 54.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG42256.1 - 6.9e-28 96.7 3.0 1.7e-12 47.6 0.1 3.7 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG42256.1 - 3.6e-24 82.2 1.0 6.9e-06 26.0 0.2 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CEG42256.1 - 1.7e-23 82.0 5.2 1.7e-05 25.0 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CEG42256.1 - 7.9e-22 77.0 3.0 2.4e-07 30.9 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF2808 PF10989.8 CEG42256.1 - 0.0078 16.2 0.1 3.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2808) Kin17_mid PF10357.9 CEG42258.1 - 1.3e-48 164.1 1.2 1.3e-48 164.1 1.2 2.4 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CEG42258.1 - 2.1e-24 85.4 1.5 5e-24 84.2 1.5 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CEG42258.1 - 0.0017 18.7 5.0 0.0034 17.7 5.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEG42258.1 - 0.0099 16.1 4.8 0.021 15.1 4.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3769 PF12600.8 CEG42258.1 - 0.014 14.3 0.4 0.017 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) DUF5401 PF17380.2 CEG42258.1 - 0.017 13.3 22.7 0.022 12.9 22.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF5634_N PF18672.1 CEG42258.1 - 0.041 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5634) KGK PF08872.10 CEG42258.1 - 1.4 9.4 11.1 1.8 9.0 1.0 2.6 1 1 1 2 2 2 0 KGK domain Asparaginase_2 PF01112.18 CEG42258.1 - 4.8 6.1 5.7 1 8.3 1.9 1.7 2 0 0 2 2 2 0 Asparaginase DUF2116 PF09889.9 CEG42258.1 - 6.2 6.9 7.0 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UPF0061 PF02696.14 CEG42259.1 - 1.5e-118 396.6 0.0 4.3e-118 395.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family adh_short PF00106.25 CEG42260.1 - 1.4e-47 161.7 0.4 1.7e-47 161.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG42260.1 - 2.2e-44 151.8 0.5 2.8e-44 151.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG42260.1 - 2.7e-09 37.2 0.0 4.6e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CEG42260.1 - 0.025 14.8 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CEG42260.1 - 0.04 14.4 0.5 0.14 12.6 0.5 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding FeS PF04060.13 CEG42260.1 - 0.14 11.8 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster adh_short_C2 PF13561.6 CEG42261.1 - 3e-46 157.9 0.2 3.5e-46 157.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG42261.1 - 1.3e-44 152.1 0.1 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG42261.1 - 8.8e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 CEG42261.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 CEG42261.1 - 0.011 16.0 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEG42261.1 - 0.036 14.1 0.1 0.062 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 CEG42261.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Anp1 PF03452.14 CEG42264.1 - 0.015 14.7 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Anp1 Cyclin_N PF00134.23 CEG42266.1 - 1.5e-09 37.6 0.4 3.3e-09 36.5 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain CTD_bind PF04818.13 CEG42266.1 - 0.033 15.0 0.4 0.033 15.0 0.4 2.5 4 0 0 4 4 4 0 RNA polymerase II-binding domain. SHIPPO-rpt PF07004.12 CEG42267.1 - 4.4e-17 62.1 31.1 0.63 11.1 0.2 12.2 12 0 0 12 12 12 9 Sperm-tail PG-rich repeat DIE2_ALG10 PF04922.12 CEG42269.1 - 2.4e-121 405.8 16.1 2.9e-121 405.5 16.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family NHL PF01436.21 CEG42269.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 NHL repeat UMP1 PF05348.11 CEG42273.1 - 2.7e-22 79.2 0.0 3.2e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DnaJ PF00226.31 CEG42274.1 - 4.8e-20 71.5 1.6 2.9e-19 68.9 0.5 2.7 2 0 0 2 2 2 1 DnaJ domain Lipase_3 PF01764.25 CEG42274.1 - 5e-06 26.4 0.0 0.063 13.1 0.0 2.9 2 0 0 2 2 2 2 Lipase (class 3) EF-hand_1 PF00036.32 CEG42274.1 - 0.00047 19.5 0.0 0.0016 17.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG42274.1 - 0.00063 19.5 0.0 0.0026 17.6 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CEG42274.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 CEG42274.1 - 0.06 13.8 0.0 0.29 11.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair DUF2974 PF11187.8 CEG42274.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RLL PF10036.9 CEG42274.1 - 0.086 12.7 1.3 1.4 8.7 0.2 2.6 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein LapA_dom PF06305.11 CEG42274.1 - 0.097 12.5 0.1 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Peptidase_C2 PF00648.21 CEG42281.1 - 1.7e-62 211.2 0.7 7.4e-60 202.5 0.0 2.6 2 0 0 2 2 2 2 Calpain family cysteine protease EF-hand_5 PF13202.6 CEG42281.1 - 2.2e-10 39.6 0.4 0.00087 18.7 0.0 2.9 2 0 0 2 2 2 2 EF hand WW PF00397.26 CEG42281.1 - 2.3e-10 40.4 2.6 7.2e-10 38.8 2.6 2.0 1 0 0 1 1 1 1 WW domain EF-hand_7 PF13499.6 CEG42281.1 - 2.7e-10 40.5 3.1 1.4e-08 35.1 0.1 4.2 4 0 0 4 4 4 1 EF-hand domain pair Calpain_III PF01067.22 CEG42281.1 - 4e-10 40.1 0.0 1.6e-08 34.9 0.0 3.0 1 1 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 CEG42281.1 - 7e-10 38.0 3.5 0.00064 19.5 0.1 4.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CEG42281.1 - 3.1e-09 35.7 5.1 0.00057 19.3 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CEG42281.1 - 5.5e-05 22.9 5.0 0.01 15.6 0.1 4.5 3 1 1 4 4 4 1 EF-hand domain pair SCAB_CC PF16712.5 CEG42281.1 - 0.33 10.8 5.6 0.93 9.3 5.6 1.7 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein FUSC PF04632.12 CEG42281.1 - 1.7 7.0 6.3 2.7 6.4 6.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BSD PF03909.17 CEG42282.1 - 1.2e-09 38.0 0.4 5.7e-09 35.8 0.4 2.2 1 0 0 1 1 1 1 BSD domain Met_10 PF02475.16 CEG42283.1 - 5.1e-68 228.8 0.2 1e-67 227.8 0.1 1.5 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.16 CEG42283.1 - 6.4e-05 22.3 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 CEG42283.1 - 0.00022 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 CEG42283.1 - 0.00037 20.1 0.0 0.00083 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CEG42283.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CEG42283.1 - 0.004 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEG42283.1 - 0.021 15.5 0.0 0.055 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CEG42283.1 - 0.021 14.7 0.0 0.23 11.3 0.0 2.1 1 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 CEG42283.1 - 0.049 13.0 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB MethyltransfD12 PF02086.15 CEG42283.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Radial_spoke_3 PF06098.11 CEG42285.1 - 7.8e-45 153.3 2.4 1e-44 153.0 2.4 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 Ly49 PF08391.10 CEG42285.1 - 2.6 8.4 5.6 0.84 10.0 2.4 1.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Synaptobrevin PF00957.21 CEG42286.1 - 2e-29 101.2 2.5 4.1e-29 100.2 2.5 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEG42286.1 - 9.6e-07 28.8 0.7 1.5e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain GP41 PF00517.17 CEG42286.1 - 0.0091 15.9 0.9 0.027 14.4 0.9 1.9 1 1 0 1 1 1 1 Retroviral envelope protein Ste5_C PF12194.8 CEG42286.1 - 0.07 13.1 2.1 0.95 9.4 0.6 2.1 1 1 1 2 2 2 0 Protein kinase Fus3-binding K-box PF01486.17 CEG42286.1 - 0.2 11.9 2.7 0.42 10.8 2.7 1.5 1 0 0 1 1 1 0 K-box region Arch_flagellin PF01917.16 CEG42286.1 - 0.27 11.4 0.9 0.5 10.5 0.9 1.5 1 1 0 1 1 1 0 Archaebacterial flagellin MCU PF04678.13 CEG42286.1 - 0.32 11.1 1.6 0.5 10.4 1.2 1.3 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF948 PF06103.11 CEG42286.1 - 2.7 8.3 5.8 1.7 8.9 0.6 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MFS_5 PF05631.14 CEG42287.1 - 1.8e-79 267.3 11.7 2.3e-79 266.9 11.7 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Sugar_tr PF00083.24 CEG42287.1 - 3e-05 23.1 19.0 0.0055 15.6 8.7 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter FYVE PF01363.21 CEG42290.1 - 1.1e-16 60.7 7.8 2e-16 59.9 7.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 CEG42290.1 - 3.9e-15 56.2 0.2 1.5e-11 44.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG42290.1 - 1.4e-12 47.6 0.8 0.00022 21.5 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG42290.1 - 1.5e-11 43.4 0.2 0.013 15.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CEG42290.1 - 9.3e-11 41.7 0.6 0.00015 22.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CEG42290.1 - 3.5e-09 37.0 0.6 0.014 15.9 0.2 5.4 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Siva PF05458.12 CEG42290.1 - 0.026 14.2 1.2 0.047 13.4 1.2 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF2370 PF10176.9 CEG42290.1 - 0.32 10.6 0.0 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) FYVE_2 PF02318.16 CEG42290.1 - 0.33 11.2 7.5 2.5 8.3 7.5 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger ATP_bind_1 PF03029.17 CEG42291.1 - 5.4e-88 294.8 0.0 6.1e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CEG42291.1 - 0.00081 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 CEG42291.1 - 0.019 14.9 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEG42291.1 - 0.052 13.9 0.0 0.55 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Fer4_NifH PF00142.18 CEG42291.1 - 0.081 12.3 0.2 0.79 9.1 0.0 2.2 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CEG42291.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEG42291.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain EF-hand_8 PF13833.6 CEG42293.1 - 0.002 17.9 0.0 0.005 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Nuf2 PF03800.14 CEG42298.1 - 2.5e-38 131.4 0.1 1e-37 129.4 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 CEG42298.1 - 4.4e-17 62.2 15.9 4.4e-17 62.2 15.9 3.8 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain rve_2 PF13333.6 CEG42298.1 - 0.41 10.9 3.1 1.8 8.8 1.4 2.5 2 0 0 2 2 2 0 Integrase core domain Evr1_Alr PF04777.13 CEG42298.1 - 0.57 10.7 3.1 1.9 9.0 2.8 2.2 1 1 0 1 1 1 0 Erv1 / Alr family DUF948 PF06103.11 CEG42298.1 - 0.58 10.5 21.9 0.36 11.1 0.4 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Flagellin_N PF00669.20 CEG42298.1 - 1.7 8.8 15.9 0.68 10.0 2.8 2.8 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF1129 PF06570.11 CEG42298.1 - 1.7 8.1 5.5 3.5 7.1 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Spc7 PF08317.11 CEG42298.1 - 3.2 6.5 55.1 0.51 9.2 20.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 CEG42298.1 - 4.5 7.3 30.5 0.35 10.9 8.7 4.0 2 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 CEG42298.1 - 5.1 6.9 43.9 0.92 9.3 13.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) LEA_4 PF02987.16 CEG42299.1 - 1.8e-23 82.3 114.5 5.3e-07 29.6 10.0 12.7 6 2 7 13 13 13 9 Late embryogenesis abundant protein YtxH PF12732.7 CEG42299.1 - 1e-06 29.2 90.9 0.007 16.9 7.2 9.9 5 1 5 10 10 10 6 YtxH-like protein Apolipoprotein PF01442.18 CEG42299.1 - 2.4e-06 27.5 57.7 4.6e-05 23.4 8.7 5.1 2 1 3 5 5 5 3 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEG42299.1 - 0.0042 17.7 72.4 0.18 12.4 5.6 9.8 2 2 8 10 10 10 5 Bacterial protein of unknown function (DUF883) DUF2205 PF10224.9 CEG42299.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.5 2 1 0 2 2 2 0 Short coiled-coil protein VHS PF00790.19 CEG42300.1 - 5.8e-27 94.3 0.0 1.4e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CEG42300.1 - 3.5e-09 36.8 3.6 1.1e-07 32.1 0.6 2.9 2 0 0 2 2 2 1 GAT domain MAGI_u1 PF16663.5 CEG42300.1 - 0.038 14.1 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Unstructured region on MAGI Spore_YhcN_YlaJ PF09580.10 CEG42300.1 - 0.19 11.8 1.7 8.5 6.4 0.2 2.7 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Hpt PF01627.23 CEG42300.1 - 0.59 10.4 3.1 2.1 8.7 0.3 2.8 3 0 0 3 3 3 0 Hpt domain FRB_dom PF08771.11 CEG42300.1 - 2.8 8.4 5.7 8.3 6.9 0.6 3.3 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Apolipoprotein PF01442.18 CEG42301.1 - 1.3e-09 38.3 5.4 1.8e-05 24.7 1.0 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEG42301.1 - 8.8e-05 23.0 12.1 0.46 11.1 0.5 3.6 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) DUF3584 PF12128.8 CEG42301.1 - 0.0038 14.8 10.9 0.0068 14.0 10.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Phasin PF05597.11 CEG42301.1 - 0.0063 16.5 9.7 0.14 12.2 1.9 3.7 2 2 2 4 4 4 1 Poly(hydroxyalcanoate) granule associated protein (phasin) WXG100 PF06013.12 CEG42301.1 - 0.0063 16.7 13.5 0.04 14.1 3.0 4.0 1 1 3 4 4 4 1 Proteins of 100 residues with WXG PLC-beta_C PF08703.10 CEG42301.1 - 0.027 14.5 0.3 0.077 13.0 0.2 1.8 2 1 0 2 2 2 0 PLC-beta C terminal ApoLp-III PF07464.11 CEG42301.1 - 0.036 14.1 12.3 0.35 11.0 5.0 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF2026 PF09641.10 CEG42301.1 - 0.042 13.5 1.3 0.063 12.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2026) DUF5601 PF18151.1 CEG42301.1 - 0.046 14.0 0.3 0.18 12.1 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) EMC3_TMCO1 PF01956.16 CEG42301.1 - 0.055 13.2 0.9 0.29 10.9 0.7 2.2 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fib_alpha PF08702.10 CEG42301.1 - 0.066 13.4 10.8 0.38 10.9 3.8 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 CEG42301.1 - 0.071 13.7 16.1 14 6.3 0.4 4.1 1 1 1 2 2 2 0 YtxH-like protein DUF2120 PF09893.9 CEG42301.1 - 0.12 12.4 1.4 1.1 9.4 0.0 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Not3 PF04065.15 CEG42301.1 - 0.15 11.5 10.0 0.049 13.1 6.4 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Exonuc_VII_L PF02601.15 CEG42301.1 - 0.16 11.6 12.2 0.13 11.8 5.8 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit CorA PF01544.18 CEG42301.1 - 0.16 11.2 1.3 0.26 10.6 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0184 PF03670.13 CEG42301.1 - 0.19 12.1 5.1 1.9 8.9 1.3 3.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) LPD39 PF18858.1 CEG42301.1 - 0.23 11.5 6.6 0.25 11.4 3.9 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 DUF2884 PF11101.8 CEG42301.1 - 0.26 10.8 10.9 0.58 9.6 7.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) YlqD PF11068.8 CEG42301.1 - 0.27 11.6 2.2 12 6.2 0.1 2.4 1 1 1 2 2 2 0 YlqD protein V-SNARE PF05008.15 CEG42301.1 - 0.35 11.3 9.2 3.7 8.0 1.2 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.11 CEG42301.1 - 0.4 8.6 9.5 2.8 5.8 5.1 1.9 1 1 0 1 1 1 0 Prominin V-ATPase_G_2 PF16999.5 CEG42301.1 - 0.48 10.9 4.8 6.9 7.1 0.5 3.0 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit Phasin_2 PF09361.10 CEG42301.1 - 0.52 10.6 12.8 0.19 12.0 3.3 3.1 2 1 2 4 4 4 0 Phasin protein STAT_alpha PF01017.20 CEG42301.1 - 0.61 10.0 3.0 3.9 7.3 3.0 2.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF4449 PF14613.6 CEG42301.1 - 0.68 10.0 12.9 3.5 7.7 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Muted PF14942.6 CEG42301.1 - 0.68 10.3 11.4 0.68 10.3 3.3 2.6 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2524 PF10732.9 CEG42301.1 - 0.72 10.2 5.3 0.99 9.7 1.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Seryl_tRNA_N PF02403.22 CEG42301.1 - 0.75 10.1 11.8 0.99 9.7 0.6 3.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1451 PF07295.11 CEG42301.1 - 0.82 9.7 7.4 0.34 10.9 2.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain OmpH PF03938.14 CEG42301.1 - 1 9.7 9.2 75 3.7 9.2 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 CEG42301.1 - 1.6 9.4 4.4 3.7 8.3 1.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.25 CEG42301.1 - 1.8 8.2 13.0 0.82 9.3 0.6 3.0 1 1 2 3 3 3 0 Syntaxin Golgin_A5 PF09787.9 CEG42301.1 - 2 7.8 9.6 2.3 7.6 7.0 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Tape_meas_lam_C PF09718.10 CEG42301.1 - 2.6 8.2 18.4 0.71 10.0 0.5 4.2 2 2 2 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) V-ATPase_G PF03179.15 CEG42301.1 - 4 8.0 7.6 1.3 9.6 3.3 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CEG42301.1 - 4.2 7.5 7.8 8.1 6.5 3.0 2.7 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) Syntaxin-6_N PF09177.11 CEG42301.1 - 4.5 7.9 9.1 3.1 8.4 1.3 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Phage_CII PF05269.11 CEG42302.1 - 0.019 15.2 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage CII protein LEA_4 PF02987.16 CEG42303.1 - 3.7e-09 36.5 45.1 0.0074 16.4 4.8 5.2 2 1 2 4 4 4 4 Late embryogenesis abundant protein Apolipoprotein PF01442.18 CEG42303.1 - 5.9e-05 23.0 30.6 0.0026 17.7 16.9 2.6 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEG42303.1 - 0.0073 16.9 34.3 0.032 14.8 4.3 5.7 3 2 3 6 6 6 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CEG42303.1 - 2.5 8.7 43.8 0.048 14.2 10.4 5.7 2 2 1 3 3 3 0 YtxH-like protein Uricase PF01014.18 CEG42307.1 - 3.7e-53 179.3 0.0 1e-27 97.0 0.0 2.0 2 0 0 2 2 2 2 Uricase WD40 PF00400.32 CEG42308.1 - 3.1e-35 119.6 10.4 5.4e-07 30.2 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 CEG42308.1 - 7.7e-26 91.0 0.6 1.5e-25 90.1 0.2 1.6 2 0 0 2 2 2 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 CEG42308.1 - 2.3e-12 47.0 0.0 0.0045 17.3 0.0 4.1 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CEG42308.1 - 7.7e-05 21.4 0.0 0.00011 20.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 CEG42308.1 - 8.3e-05 22.6 0.0 0.00085 19.2 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEG42308.1 - 0.0071 15.0 0.5 0.063 11.9 0.2 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ECM11 PF15463.6 CEG42308.1 - 0.041 14.5 0.1 0.097 13.2 0.1 1.6 1 0 0 1 1 1 0 Extracellular mutant protein 11 Cornichon PF03311.14 CEG42309.1 - 7.3e-34 116.7 3.2 8.6e-34 116.5 3.2 1.1 1 0 0 1 1 1 1 Cornichon protein IML1 PF12257.8 CEG42310.1 - 4.7e-79 265.5 0.0 7.2e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DUF1972 PF09314.11 CEG42310.1 - 0.08 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) zf-TAZ PF02135.16 CEG42311.1 - 2.9e-23 82.1 36.7 3.1e-14 53.2 15.0 5.5 6 1 0 6 6 3 2 TAZ zinc finger GMC_oxred_N PF00732.19 CEG42311.1 - 2.5e-22 79.6 0.0 1.1e-21 77.5 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase HAT_KAT11 PF08214.11 CEG42311.1 - 6.1e-20 71.8 0.4 6.1e-20 71.8 0.4 4.4 3 1 0 3 3 2 1 Histone acetylation protein Bromodomain PF00439.25 CEG42311.1 - 1.9e-18 66.3 0.1 5.8e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 Bromodomain ZZ PF00569.17 CEG42311.1 - 3.6e-10 39.5 9.0 3.6e-10 39.5 9.0 3.9 5 0 0 5 5 3 1 Zinc finger, ZZ type PAN_4 PF14295.6 CEG42311.1 - 1.2e-08 34.7 7.3 1.2e-08 34.7 7.3 3.4 2 0 0 2 2 1 1 PAN domain KIX_2 PF16987.5 CEG42311.1 - 7.4e-07 29.1 1.5 7.4e-07 29.1 1.5 3.5 3 0 0 3 3 1 1 KIX domain GMC_oxred_C PF05199.13 CEG42311.1 - 1.8e-06 28.5 5.4 2.3e-06 28.2 0.1 3.6 3 0 0 3 3 3 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CEG42311.1 - 3.3e-06 27.2 0.0 1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEG42311.1 - 0.00013 21.3 0.3 0.00089 18.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family PHD PF00628.29 CEG42311.1 - 0.00026 20.8 0.7 0.00026 20.8 0.7 5.1 4 0 0 4 4 3 1 PHD-finger DUF902 PF06001.13 CEG42311.1 - 0.0028 18.1 6.2 0.0041 17.6 4.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) FAD_binding_2 PF00890.24 CEG42311.1 - 0.0028 16.8 3.1 0.023 13.8 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 CEG42311.1 - 0.0032 17.1 0.8 0.41 10.2 0.5 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEG42311.1 - 0.0098 15.2 0.0 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEG42311.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.5 2 0 0 2 2 2 0 FAD binding domain KIX PF02172.16 CEG42311.1 - 0.045 14.0 0.9 0.16 12.3 0.1 2.5 2 0 0 2 2 1 0 KIX domain NPP1 PF05630.11 CEG42318.1 - 2e-47 161.9 0.1 2.3e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Nuc_deoxyri_tr2 PF15891.5 CEG42321.1 - 1.3e-31 109.1 0.1 2e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Peptidase_M1 PF01433.20 CEG42322.1 - 1.2e-83 280.0 0.8 1.9e-83 279.3 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CEG42322.1 - 1.6e-75 254.6 6.5 2.8e-75 253.8 2.1 2.6 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CEG42322.1 - 2.8e-33 115.7 0.1 4e-32 111.9 0.0 2.6 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain SIR2 PF02146.17 CEG42323.1 - 5.9e-05 23.1 0.0 0.014 15.4 0.0 2.7 2 1 0 2 2 2 2 Sir2 family Zn-ribbon_8 PF09723.10 CEG42323.1 - 0.12 12.6 0.6 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Rhodanese_C PF12368.8 CEG42323.1 - 0.14 12.5 0.1 0.94 9.9 0.0 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal DUF4922 PF16269.5 CEG42324.1 - 0.00053 19.8 0.0 0.00096 19.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) Pkinase PF00069.25 CEG42327.1 - 3.4e-32 111.8 0.0 4.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42327.1 - 4.6e-22 78.5 0.0 6.8e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42327.1 - 0.00031 20.1 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RXLR PF16810.5 CEG42328.1 - 2e-12 47.7 0.0 3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Nramp PF01566.18 CEG42329.1 - 8.4e-116 386.8 16.5 8.4e-116 386.8 16.5 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Med26 PF08711.11 CEG42330.1 - 2.1e-08 34.1 0.7 4.2e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Iso_dh PF00180.20 CEG42331.1 - 3.1e-119 398.2 0.0 3.5e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RXLR PF16810.5 CEG42332.1 - 0.0051 17.3 0.1 0.0075 16.7 0.1 1.4 1 1 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity ETRAMP PF09716.10 CEG42332.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Patched PF02460.18 CEG42336.1 - 1.2e-66 225.4 17.0 2.3e-46 158.3 1.8 2.8 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CEG42336.1 - 1.5e-36 125.5 9.9 1.5e-36 125.5 9.9 4.0 3 2 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CEG42336.1 - 0.011 14.7 1.1 0.011 14.7 1.1 3.9 5 0 0 5 5 5 0 MMPL family DUF3265 PF11665.8 CEG42336.1 - 0.65 10.3 3.0 1.2 9.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) RVT_2 PF07727.14 CEG42337.1 - 6e-22 78.5 0.3 9.9e-22 77.7 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 CEG42338.1 - 3.3e-21 75.8 0.1 8.1e-09 35.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase LRR_8 PF13855.6 CEG42338.1 - 5e-17 61.4 32.2 3.6e-06 26.6 8.2 5.2 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CEG42338.1 - 9.5e-11 41.8 38.8 3e-05 24.3 0.3 7.0 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG42338.1 - 5.9e-05 22.6 1.4 0.0028 17.2 0.1 2.6 1 1 1 2 2 2 1 Leucine-rich repeat Pkinase PF00069.25 CEG42338.1 - 0.00027 20.4 0.1 3.5 6.9 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain LRR_1 PF00560.33 CEG42338.1 - 0.0032 17.8 20.1 15 6.6 0.0 8.4 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 CEG42338.1 - 2.7 8.3 21.0 28 5.1 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat DcpS_C PF11969.8 CEG42339.1 - 1.1e-18 67.7 0.5 1.8e-18 67.1 0.5 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEG42339.1 - 3e-10 40.7 3.7 6.1e-10 39.7 3.7 1.4 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 CEG42339.1 - 0.057 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Sugar_tr PF00083.24 CEG42340.1 - 3.3e-41 141.6 12.2 7.1e-41 140.5 12.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TPD PF14811.6 CEG42340.1 - 2e-31 108.7 0.0 3.6e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif MFS_1 PF07690.16 CEG42340.1 - 9.7e-12 44.5 20.6 9.7e-12 44.5 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_3 PF13812.6 CEG42340.1 - 0.00013 21.9 0.0 0.85 9.7 0.1 3.9 2 2 2 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 CEG42340.1 - 0.00059 20.0 2.6 0.15 12.3 0.0 3.9 4 1 1 5 5 5 1 PPR repeat family PPR_long PF17177.4 CEG42340.1 - 0.057 12.8 0.1 0.057 12.8 0.1 2.7 2 2 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Mit_KHE1 PF10173.9 CEG42340.1 - 1.8 8.6 7.2 4 7.5 7.2 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Myosin_head PF00063.21 CEG42342.1 - 7.1e-199 662.3 0.0 1.1e-198 661.8 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 CEG42342.1 - 1.5e-10 41.1 0.0 5.8e-10 39.1 0.0 2.1 1 0 0 1 1 1 1 PX domain IQ PF00612.27 CEG42342.1 - 0.0035 17.0 29.0 0.022 14.5 1.1 5.6 5 0 0 5 5 5 2 IQ calmodulin-binding motif AAA_16 PF13191.6 CEG42342.1 - 0.056 13.8 0.0 0.056 13.8 0.0 4.6 3 1 1 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CEG42342.1 - 0.088 13.1 2.5 0.16 12.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG42342.1 - 1.5 9.3 5.6 3.8 8.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 CEG42342.1 - 4.3 7.0 12.8 83 2.8 11.4 2.8 2 0 0 2 2 2 0 AAA domain FtsJ PF01728.19 CEG42343.1 - 5e-53 179.8 0.0 6.4e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CEG42343.1 - 0.002 17.9 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF2390 PF09523.10 CEG42343.1 - 0.033 14.5 1.3 0.068 13.5 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF4201 PF13870.6 CEG42344.1 - 2.2e-39 135.0 29.5 2.2e-39 135.0 29.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) YabA PF06156.13 CEG42344.1 - 0.46 11.1 27.4 0.083 13.5 6.5 4.2 1 1 2 3 3 3 0 Initiation control protein YabA Ycf54 PF10674.9 CEG42344.1 - 0.62 10.4 5.1 0.25 11.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) NPV_P10 PF05531.12 CEG42344.1 - 3.9 8.0 5.8 29 5.2 1.8 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ricin_B_lectin PF00652.22 CEG42348.1 - 9.6e-17 61.4 3.2 1.5e-16 60.8 3.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 CEG42348.1 - 7.8e-09 35.5 1.2 8.9e-06 25.5 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 TatD_DNase PF01026.21 CEG42348.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase HMG_box PF00505.19 CEG42349.1 - 5.9e-38 129.1 15.5 6.1e-21 74.6 5.4 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEG42349.1 - 3.2e-26 91.7 14.6 8.3e-13 48.7 1.7 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 CEG42349.1 - 0.16 12.0 15.3 0.21 11.6 2.3 2.7 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Ccdc124 PF06244.12 CEG42349.1 - 3.9 8.0 18.8 0.55 10.8 7.5 3.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 PGK PF00162.19 CEG42350.1 - 2.3e-147 490.9 3.5 2.5e-147 490.7 3.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 CEG42350.1 - 0.0015 18.5 0.2 0.016 15.2 0.0 2.7 2 1 0 2 2 2 1 PA domain Aida_C2 PF14186.6 CEG42353.1 - 4.8e-31 107.4 0.0 8.8e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal adhesion Ank_2 PF12796.7 CEG42353.1 - 7.3e-20 71.4 0.3 2.4e-08 34.4 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG42353.1 - 5.7e-19 67.9 1.6 3.8e-07 30.3 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG42353.1 - 4.6e-17 62.2 0.7 2.4e-06 27.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CEG42353.1 - 9.2e-17 60.7 0.4 2.6e-05 24.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CEG42353.1 - 4.9e-16 57.2 0.3 0.011 16.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 CEG42353.1 - 1.8e-13 50.9 0.1 4.8e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CEG42353.1 - 0.0062 16.2 2.7 0.0062 16.2 2.7 3.9 4 0 0 4 4 4 2 IQ calmodulin-binding motif PH_11 PF15413.6 CEG42353.1 - 0.027 14.9 0.2 0.11 12.9 0.2 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PriA_C PF18074.1 CEG42353.1 - 0.12 13.2 1.3 0.54 11.1 1.0 2.2 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain Brix PF04427.18 CEG42354.1 - 2.3e-33 115.9 0.0 3.4e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.25 CEG42354.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Bromodomain FYVE PF01363.21 CEG42355.1 - 2.6e-06 27.5 14.8 5.8e-06 26.4 14.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG42355.1 - 0.0045 17.2 9.9 0.011 16.0 9.9 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Dpy-30 PF05186.13 CEG42358.1 - 2.2e-10 40.0 0.0 5.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif LRR_8 PF13855.6 CEG42359.1 - 1.9e-45 152.5 62.3 6.5e-11 41.8 4.9 10.0 4 2 4 10 10 10 9 Leucine rich repeat PIP5K PF01504.18 CEG42359.1 - 2.1e-38 132.1 0.3 1.1e-28 100.2 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase LRR_4 PF12799.7 CEG42359.1 - 2.1e-32 110.6 63.2 8.1e-06 26.1 0.7 10.5 6 2 5 11 11 11 11 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.24 CEG42359.1 - 1.2e-24 86.8 0.3 3e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CEG42359.1 - 8.4e-14 51.5 15.9 8.4e-14 51.5 15.9 2.2 2 0 0 2 2 1 1 FYVE zinc finger EF-hand_6 PF13405.6 CEG42359.1 - 8e-06 25.4 0.4 0.075 13.0 0.0 3.9 4 0 0 4 4 3 2 EF-hand domain EF-hand_1 PF00036.32 CEG42359.1 - 1.2e-05 24.4 0.1 0.094 12.3 0.0 3.4 2 0 0 2 2 2 2 EF hand LRR_9 PF14580.6 CEG42359.1 - 4.1e-05 23.1 17.7 0.018 14.6 1.1 5.3 2 2 3 5 5 5 4 Leucine-rich repeat EF-hand_7 PF13499.6 CEG42359.1 - 0.00022 21.6 1.1 0.0029 18.0 0.6 3.0 2 1 2 4 4 3 2 EF-hand domain pair LRR_1 PF00560.33 CEG42359.1 - 0.00073 19.8 51.3 3.1 8.7 0.2 14.5 15 1 0 15 15 14 1 Leucine Rich Repeat PDZ PF00595.24 CEG42359.1 - 0.0016 18.7 0.0 0.0047 17.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG42359.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.6 CEG42359.1 - 0.45 10.7 33.6 0.49 10.6 0.2 10.1 10 0 0 10 10 10 0 Leucine Rich repeat EF-hand_8 PF13833.6 CEG42359.1 - 0.91 9.4 5.8 2.4 8.1 0.1 3.9 4 1 0 4 4 4 0 EF-hand domain pair Aa_trans PF01490.18 CEG42360.1 - 2e-63 214.5 28.6 2.7e-63 214.1 28.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG42360.1 - 3.6e-14 52.6 12.7 3.6e-14 52.6 12.7 1.9 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family NTP_transf_2 PF01909.23 CEG42361.1 - 4e-05 23.8 0.0 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEG42361.1 - 0.073 13.3 0.3 0.23 11.7 0.3 1.9 1 0 0 1 1 1 0 Cid1 family poly A polymerase DUF1664 PF07889.12 CEG42361.1 - 1.4 9.0 3.9 3 7.9 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Retrotran_gag_2 PF14223.6 CEG42362.1 - 3.6e-32 110.9 0.1 4.6e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG42362.1 - 0.16 11.7 1.0 0.43 10.3 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Glyco_hydro81C PF17652.1 CEG42363.1 - 1.8e-103 346.5 0.6 2.5e-103 346.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG42363.1 - 7.1e-46 156.9 0.4 1.1e-45 156.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Ribosomal_L40e PF01020.17 CEG42364.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Ribosomal L40e family cNMP_binding PF00027.29 CEG42366.1 - 3e-22 78.5 0.3 9e-06 25.7 0.0 4.2 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain zf-CCHC_5 PF14787.6 CEG42366.1 - 0.13 12.0 1.7 0.28 10.9 1.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Zip PF02535.22 CEG42367.1 - 3.4e-06 26.5 2.0 4.2e-06 26.2 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter MtrD PF04207.12 CEG42367.1 - 0.015 15.0 0.2 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D ABC_tran PF00005.27 CEG42369.1 - 2.1e-26 93.1 0.0 3.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CEG42369.1 - 4.2e-16 59.0 22.5 2.9e-09 36.7 4.5 2.5 2 1 1 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 CEG42369.1 - 7.7e-10 39.1 1.4 1.2e-05 25.3 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG42369.1 - 9.7e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG42369.1 - 1.4e-05 25.6 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEG42369.1 - 0.00013 21.7 0.1 0.00036 20.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG42369.1 - 0.00074 19.8 0.0 0.0038 17.5 0.0 2.1 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 CEG42369.1 - 0.0014 18.6 0.2 0.031 14.2 0.1 2.2 2 0 0 2 2 2 1 NTPase RsgA_GTPase PF03193.16 CEG42369.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 CEG42369.1 - 0.004 17.6 0.0 0.015 15.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEG42369.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEG42369.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CEG42369.1 - 0.014 15.1 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase ATP-synt_ab PF00006.25 CEG42369.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 CEG42369.1 - 0.029 14.3 0.0 0.076 12.9 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CEG42369.1 - 0.037 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CEG42369.1 - 0.04 14.5 0.0 0.078 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEG42369.1 - 0.041 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CEG42369.1 - 0.045 13.5 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG42369.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEG42369.1 - 0.077 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEG42369.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CEG42369.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEG42369.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 CEG42369.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 CEG42369.1 - 0.13 12.0 0.1 0.23 11.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_S26e PF01283.19 CEG42370.1 - 2.1e-48 163.2 7.8 2.3e-48 163.1 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e 2Fe-2S_thioredx PF01257.19 CEG42371.1 - 3.1e-62 208.7 0.1 4e-62 208.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1678 PF07913.11 CEG42372.1 - 0.081 12.7 0.2 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1678) KleE PF17394.2 CEG42372.1 - 1.2 9.4 8.1 2.1 8.6 1.2 2.2 1 1 1 2 2 2 0 Uncharacterized KleE stable inheritance protein TMF_DNA_bd PF12329.8 CEG42375.1 - 0.018 15.0 1.2 0.018 15.0 1.2 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.6 CEG42375.1 - 0.053 13.6 7.6 0.46 10.6 1.3 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 NEMO PF11577.8 CEG42375.1 - 0.064 13.3 1.2 0.064 13.3 1.2 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Tup_N PF08581.10 CEG42375.1 - 0.23 11.8 5.6 4.5 7.7 0.3 2.6 3 0 0 3 3 3 0 Tup N-terminal DNA_meth_N PF18284.1 CEG42378.1 - 0.087 12.7 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 DNA methylase N-terminal domain Ribosomal_L1 PF00687.21 CEG42381.1 - 5.4e-46 156.9 2.4 5.4e-46 156.9 2.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2052 PF09747.9 CEG42381.1 - 3.6 7.7 11.2 1.3 9.1 8.7 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Steroid_dh PF02544.16 CEG42382.1 - 4e-32 111.3 0.7 4e-32 111.3 0.7 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CEG42382.1 - 2.2e-05 24.1 0.2 3.2e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.6 CEG42382.1 - 0.00041 20.8 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain PEMT PF04191.13 CEG42382.1 - 0.00044 20.6 2.9 0.00046 20.6 0.2 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase ubiquitin PF00240.23 CEG42382.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Ubiquitin_4 PF18036.1 CEG42382.1 - 0.12 12.5 0.0 0.94 9.6 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Tyrosinase PF00264.20 CEG42383.1 - 3.7e-26 92.8 0.0 7.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase ABC2_membrane PF01061.24 CEG42384.1 - 7.7e-42 143.1 17.8 1.1e-41 142.6 17.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CEG42384.1 - 6.8e-27 94.7 0.0 1.3e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEG42384.1 - 9.3e-08 32.2 0.1 0.004 17.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEG42384.1 - 0.00022 21.2 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEG42384.1 - 0.001 19.5 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEG42384.1 - 0.0017 18.1 0.2 0.0035 17.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CEG42384.1 - 0.0038 16.7 0.1 0.1 12.1 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CEG42384.1 - 0.0042 16.2 16.6 0.0042 16.2 16.6 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 CEG42384.1 - 0.0049 17.4 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG42384.1 - 0.014 15.6 0.0 0.33 11.2 0.0 2.4 1 1 0 2 2 2 0 AAA domain DUF1462 PF07315.11 CEG42384.1 - 0.079 13.2 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) Phyto-Amp PF15438.6 CEG42384.1 - 0.17 11.7 0.4 0.33 10.8 0.4 1.4 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma AP-5_subunit_s1 PF15001.6 CEG42386.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 XRCC4 PF06632.12 CEG42387.1 - 0.017 14.0 22.2 0.034 13.0 22.2 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ThiI PF02568.14 CEG42387.1 - 0.075 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) CCDC53 PF10152.9 CEG42387.1 - 5.6 7.4 12.2 7.5 7.0 2.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Sulfatase PF00884.23 CEG42388.1 - 1.3e-29 103.6 0.0 2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CEG42388.1 - 3.6e-06 25.9 0.0 6.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CEG42388.1 - 0.0001 22.0 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CitMHS PF03600.16 CEG42388.1 - 0.0096 15.2 0.0 0.015 14.5 0.0 1.3 1 1 0 1 1 1 1 Citrate transporter Metalloenzyme PF01676.18 CEG42388.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily CBAH PF02275.18 CEG42390.1 - 0.0065 16.2 0.0 0.022 14.4 0.0 1.7 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family zf-NADH-PPase PF09297.11 CEG42392.1 - 0.012 15.2 5.8 0.15 11.8 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 CEG42392.1 - 0.022 14.5 7.5 0.22 11.3 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEG42392.1 - 0.047 13.1 5.0 0.2 11.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CEG42392.1 - 0.17 11.9 8.4 0.078 13.0 4.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 CEG42392.1 - 0.26 11.3 3.1 0.33 11.0 3.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 CEG42392.1 - 2.6 8.0 11.2 2.2 8.3 1.9 3.0 2 1 1 3 3 3 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 CEG42392.1 - 2.7 8.2 5.9 5.1 7.3 5.9 1.8 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.16 CEG42392.1 - 5.6 6.9 7.7 15 5.5 2.1 2.6 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 CEG42392.1 - 9.7 6.4 17.7 0.95 9.6 1.3 2.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 ACBP PF00887.19 CEG42393.1 - 8e-16 58.0 0.0 2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein SF-assemblin PF06705.11 CEG42393.1 - 0.0045 16.4 0.9 0.0045 16.4 0.9 1.8 1 1 1 2 2 2 1 SF-assemblin/beta giardin Cep57_MT_bd PF06657.13 CEG42393.1 - 0.019 15.4 1.5 0.019 15.4 1.5 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAD_binding_1 PF00667.20 CEG42393.1 - 0.03 13.9 1.1 0.055 13.0 0.7 1.6 2 0 0 2 2 2 0 FAD binding domain CREPT PF16566.5 CEG42393.1 - 0.11 12.6 8.1 0.18 12.0 6.5 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FapA PF03961.13 CEG42393.1 - 0.16 10.5 3.4 0.22 10.1 3.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A BLI1 PF17324.2 CEG42393.1 - 0.41 11.3 6.3 12 6.6 5.3 2.4 1 1 1 2 2 2 0 BLOC-1 interactor 1 DASH_Duo1 PF08651.10 CEG42393.1 - 0.73 9.7 5.5 20 5.0 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 Occludin_ELL PF07303.13 CEG42393.1 - 8.4 7.2 8.5 19 6.1 3.8 2.7 2 1 0 2 2 2 0 Occludin homology domain Amidase PF01425.21 CEG42394.1 - 1.1e-21 77.4 7.2 2.4e-13 49.8 0.0 3.7 3 1 1 4 4 4 3 Amidase RRM_1 PF00076.22 CEG42396.1 - 2.6e-10 40.0 0.0 1.6e-07 31.0 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 CEG42396.1 - 0.00091 18.6 0.0 0.0033 16.9 0.0 2.0 1 0 0 1 1 1 1 Lsm interaction motif UIM PF02809.20 CEG42396.1 - 1.5 8.9 4.9 1.8 8.7 2.1 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif F-box_5 PF18511.1 CEG42397.1 - 0.14 11.8 0.5 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 F-box CBM_1 PF00734.18 CEG42398.1 - 1.8e-07 31.0 2.8 2.7e-07 30.4 2.8 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Chi-conotoxin PF16981.5 CEG42398.1 - 0.018 15.2 1.4 0.033 14.4 0.1 1.9 1 1 1 2 2 2 0 chi-Conotoxin or t superfamily GATase_3 PF07685.14 CEG42398.1 - 0.15 11.7 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CBM_1 PF00734.18 CEG42399.1 - 1.8e-15 56.5 17.2 5.5e-10 39.0 5.8 2.6 2 0 0 2 2 2 2 Fungal cellulose binding domain Toxin_7 PF05980.12 CEG42399.1 - 0.32 11.3 4.4 5.7 7.3 0.4 2.3 2 0 0 2 2 2 0 Toxin 7 Rootletin PF15035.6 CEG42400.1 - 0.005 16.9 5.1 0.005 16.9 5.1 3.6 4 1 1 5 5 5 1 Ciliary rootlet component, centrosome cohesion DUF4359 PF14271.6 CEG42400.1 - 9.1 7.1 8.5 0.38 11.5 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4359) RSN1_7TM PF02714.15 CEG42401.1 - 3.2e-06 26.7 7.8 3.2e-06 26.7 7.8 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEG42401.1 - 2.8e-05 24.4 13.2 0.0085 16.3 8.1 3.8 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CEG42401.1 - 0.015 15.1 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tub PF01167.18 CEG42402.1 - 8.9e-27 94.4 0.0 1.1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Tub family SmpB PF01668.18 CEG42403.1 - 1.8e-27 96.0 0.0 2.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 SmpB protein Ras PF00071.22 CEG42404.1 - 8.8e-58 194.5 0.0 1e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG42404.1 - 4e-36 123.9 0.0 6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG42404.1 - 3.9e-11 42.7 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG42404.1 - 4.1e-06 26.3 0.0 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG42404.1 - 7.6e-06 25.9 0.5 0.022 14.7 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG42404.1 - 2.2e-05 24.5 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEG42404.1 - 0.002 17.6 0.0 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEG42404.1 - 0.0058 16.2 0.1 0.033 13.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG42404.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CEG42404.1 - 0.02 15.4 0.1 0.036 14.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CEG42404.1 - 0.021 14.5 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CEG42404.1 - 0.032 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 CEG42404.1 - 0.06 12.8 0.1 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CEG42404.1 - 0.076 12.4 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CEG42404.1 - 0.083 12.0 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEG42404.1 - 0.093 13.0 0.1 0.45 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain AP_endonuc_2 PF01261.24 CEG42404.1 - 0.094 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AAA_5 PF07728.14 CEG42404.1 - 0.12 12.4 0.1 0.36 10.8 0.1 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Lar_N PF09861.9 CEG42404.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain ATPase PF06745.13 CEG42404.1 - 0.17 11.2 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 KaiC IBR PF01485.21 CEG42407.1 - 1.2e-23 83.0 43.9 1.2e-15 57.4 3.8 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 CEG42407.1 - 0.0011 19.3 3.6 0.0011 19.3 3.6 3.3 2 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CEG42407.1 - 0.0026 17.6 6.9 0.0026 17.6 6.9 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG42407.1 - 0.022 14.7 11.5 0.022 14.7 11.5 4.2 2 1 1 3 3 3 0 zinc-RING finger domain Pkinase PF00069.25 CEG42408.1 - 3e-45 154.6 0.0 5.6e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42408.1 - 1.3e-44 152.5 0.0 2.1e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 CEG42408.1 - 1.7e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEG42408.1 - 6.5e-06 26.5 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 CEG42408.1 - 1.8e-05 23.7 0.4 1.8e-05 23.7 0.4 2.0 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 CEG42408.1 - 0.0015 19.0 0.9 0.0015 19.0 0.9 1.9 2 0 0 2 2 1 1 PH domain APH PF01636.23 CEG42408.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG42408.1 - 0.037 13.0 0.3 0.11 11.5 0.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CEG42408.1 - 0.076 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PH_11 PF15413.6 CEG42408.1 - 0.083 13.3 0.8 0.37 11.2 0.8 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4724 PF15852.5 CEG42408.1 - 3.5 8.2 6.6 2.5 8.6 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4724) CHAD PF05235.14 CEG42410.1 - 0.019 14.9 0.4 0.024 14.6 0.4 1.2 1 0 0 1 1 1 0 CHAD domain Syntaxin-6_N PF09177.11 CEG42410.1 - 0.06 13.9 6.8 0.54 10.8 6.4 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal T2SSF PF00482.23 CEG42410.1 - 0.16 12.0 0.6 0.25 11.3 0.6 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CCDC-167 PF15188.6 CEG42410.1 - 9.7 6.6 10.5 1 9.8 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RRM_1 PF00076.22 CEG42412.1 - 3.8e-09 36.2 0.0 9.5e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHC_N2 PF08393.13 CEG42412.1 - 0.0028 16.9 5.6 0.034 13.3 1.8 2.2 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 RP-C_C PF11800.8 CEG42412.1 - 0.029 14.5 4.6 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CK2S PF15011.6 CEG42412.1 - 0.086 12.7 6.4 0.2 11.6 0.0 2.8 2 1 1 3 3 3 0 Casein Kinase 2 substrate OmpH PF03938.14 CEG42412.1 - 0.17 12.2 12.3 0.11 12.8 7.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 CEG42412.1 - 1 9.8 0.0 1 9.8 0.0 2.9 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CEG42412.1 - 3.7 7.7 7.6 1.1 9.4 0.3 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 CEG42412.1 - 6.3 7.0 12.3 2.6 8.3 9.7 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein MRC1 PF09444.10 CEG42412.1 - 7.4 7.1 8.4 0.47 11.0 2.2 2.1 3 0 0 3 3 3 0 MRC1-like domain ELFV_dehydrog PF00208.21 CEG42414.1 - 5.7e-61 206.3 0.1 7.4e-61 206.0 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CEG42414.1 - 4.2e-47 159.3 0.0 1.3e-43 147.9 0.0 2.4 2 0 0 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CEG42414.1 - 0.019 15.4 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 CEG42415.1 - 3.8e-08 33.0 0.1 8e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEG42415.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 CEG42415.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase PolyA_pol PF01743.20 CEG42416.1 - 0.0018 18.7 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain DUF533 PF04391.12 CEG42416.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Neur_chan_memb PF02932.16 CEG42417.1 - 6.7 6.7 5.4 8.4 6.4 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aa_trans PF01490.18 CEG42418.1 - 1.1e-61 208.7 27.0 1.4e-61 208.4 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.21 CEG42419.1 - 1.9e-40 138.5 0.8 1.9e-40 138.5 0.8 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEG42419.1 - 5.3e-39 133.6 3.3 5.3e-39 133.6 3.3 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CEG42419.1 - 6e-20 72.4 0.3 8.2e-11 42.6 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG42419.1 - 7.2e-18 64.5 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEG42419.1 - 2.4e-10 39.9 0.0 6.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG42419.1 - 2.6e-06 27.4 0.3 0.0008 19.2 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF5392 PF17370.2 CEG42419.1 - 2 8.5 3.5 4.8 7.3 3.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5392) ubiquitin PF00240.23 CEG42421.1 - 2.3e-14 52.9 1.0 1.9e-07 30.7 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEG42421.1 - 0.00017 21.3 0.1 0.32 10.8 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Retrotran_gag_2 PF14223.6 CEG42424.1 - 0.0011 18.6 0.5 0.05 13.3 0.1 2.3 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CEG42424.1 - 0.029 14.2 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain WD40 PF00400.32 CEG42425.1 - 2.3e-15 56.7 11.4 0.00016 22.4 0.0 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat WD40_like PF17005.5 CEG42425.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 1 0 2 2 2 0 WD40-like domain TPT PF03151.16 CEG42426.1 - 2.9e-25 89.2 22.5 3.6e-25 88.9 22.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CEG42426.1 - 3.7e-06 26.4 20.5 5.7e-06 25.7 20.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEG42426.1 - 8.3e-05 22.8 16.7 8.3e-05 22.8 16.7 2.8 2 1 1 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 CEG42426.1 - 0.00063 19.1 26.3 0.00077 18.8 25.1 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport PcrB PF01884.17 CEG42426.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 PcrB family F-box-like PF12937.7 CEG42427.1 - 6.1e-05 22.8 0.5 0.00029 20.6 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEG42427.1 - 0.0013 18.6 2.7 0.0015 18.4 0.8 2.1 2 0 0 2 2 2 1 F-box domain zf-C2H2 PF00096.26 CEG42427.1 - 0.0023 18.3 13.1 0.3 11.6 0.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3 PF13878.6 CEG42427.1 - 0.0075 16.1 0.2 0.024 14.5 0.2 1.9 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-C2H2_6 PF13912.6 CEG42427.1 - 0.31 11.1 6.6 5.1 7.2 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger NAD_binding_2 PF03446.15 CEG42428.1 - 3.7e-42 144.2 0.2 5e-42 143.8 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEG42428.1 - 9.4e-22 77.5 0.0 1.9e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CEG42428.1 - 0.067 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase COPI_assoc PF08507.10 CEG42429.1 - 3.7e-07 30.3 10.4 5.1e-07 29.8 10.4 1.1 1 0 0 1 1 1 1 COPI associated protein Guanylate_cyc PF00211.20 CEG42434.1 - 2.5e-07 30.5 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UCMA PF17085.5 CEG42435.1 - 0.039 14.0 4.4 0.06 13.4 4.4 1.3 1 0 0 1 1 1 0 Unique cartilage matrix associated protein DDRGK PF09756.9 CEG42435.1 - 0.048 13.2 6.3 0.07 12.7 6.3 1.2 1 0 0 1 1 1 0 DDRGK domain 4HB_MCP_1 PF12729.7 CEG42435.1 - 0.45 10.0 4.6 0.87 9.1 4.6 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction cobW PF02492.19 CEG42436.1 - 2.8e-51 173.6 1.5 1.3e-37 129.1 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEG42436.1 - 3.8e-18 65.2 0.0 2.3e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 CEG42436.1 - 0.0032 16.5 0.2 0.67 8.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CEG42436.1 - 0.0038 17.2 0.2 2 8.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 CEG42436.1 - 0.0048 16.9 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CEG42436.1 - 0.0074 16.7 0.1 0.031 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CEG42436.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CEG42436.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.14 CEG42436.1 - 0.03 14.2 0.1 0.08 12.8 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 CEG42436.1 - 0.058 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEG42436.1 - 0.074 13.0 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CEG42436.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CEG42436.1 - 0.12 12.9 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 CEG42436.1 - 0.16 12.5 0.3 1.2 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Phage_tail_S PF05069.13 CEG42442.1 - 0.055 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family PAS PF00989.25 CEG42447.1 - 9.9e-117 383.1 0.0 1.7e-23 82.8 0.0 6.1 6 0 0 6 6 6 6 PAS fold PAS_4 PF08448.10 CEG42447.1 - 2.9e-79 262.5 0.0 2e-12 47.3 0.0 6.0 6 0 0 6 6 6 6 PAS fold PAS_9 PF13426.7 CEG42447.1 - 3.9e-75 248.8 5.7 1.9e-12 47.4 0.0 6.1 6 0 0 6 6 6 6 PAS domain PAS_3 PF08447.12 CEG42447.1 - 8.5e-40 134.9 0.0 1.1e-07 32.1 0.0 6.2 6 0 0 6 6 6 6 PAS fold PAS_8 PF13188.7 CEG42447.1 - 6.2e-25 86.7 0.1 0.0016 18.4 0.0 6.5 6 0 0 6 6 6 6 PAS domain PAS_10 PF13596.6 CEG42447.1 - 2.3e-19 69.9 0.0 0.04 14.5 0.0 6.1 6 0 0 6 6 6 4 PAS domain PAS_7 PF12860.7 CEG42447.1 - 2.3e-09 37.4 6.0 3.8 7.7 0.0 8.3 7 4 0 7 7 7 4 PAS fold sCache_3_3 PF17202.4 CEG42447.1 - 0.001 19.5 0.8 4.8 7.7 0.0 5.4 5 1 0 5 5 5 1 Single cache domain 3 tRNA_anti-like PF12869.7 CEG42447.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.6 4 0 0 4 4 4 0 tRNA_anti-like Ras PF00071.22 CEG42449.1 - 8.9e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG42449.1 - 6.8e-13 48.9 0.0 8.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG42449.1 - 0.0061 16.0 0.0 0.0078 15.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG42449.1 - 0.015 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEG42449.1 - 0.038 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CEG42449.1 - 0.049 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CEG42449.1 - 0.059 13.6 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEG42449.1 - 0.063 13.2 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 CEG42449.1 - 0.19 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain PAS PF00989.25 CEG42450.1 - 9.6e-68 225.3 0.6 4.1e-20 71.9 0.0 4.5 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 CEG42450.1 - 2.4e-45 153.3 0.0 3.3e-12 46.6 0.0 4.5 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 CEG42450.1 - 4.5e-43 145.8 4.2 9e-12 45.2 0.1 4.4 4 0 0 4 4 4 4 PAS domain HATPase_c PF02518.26 CEG42450.1 - 2e-25 89.5 0.0 7.6e-25 87.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 CEG42450.1 - 4.6e-24 84.5 0.0 0.00012 22.3 0.0 4.4 4 0 0 4 4 4 4 PAS fold Response_reg PF00072.24 CEG42450.1 - 4.6e-20 71.9 0.0 1.9e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CEG42450.1 - 2.3e-17 62.8 0.1 7.8e-17 61.1 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 CEG42450.1 - 4.5e-13 48.9 0.1 0.00069 19.6 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_10 PF13596.6 CEG42450.1 - 4.9e-08 33.5 0.3 0.011 16.3 0.0 4.3 4 0 0 4 4 4 2 PAS domain Hpt PF01627.23 CEG42450.1 - 3.8e-06 27.1 0.8 1.4e-05 25.2 0.8 2.0 1 0 0 1 1 1 1 Hpt domain HATPase_c_3 PF13589.6 CEG42450.1 - 0.093 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF2_N PF00176.23 CEG42451.1 - 2e-66 224.1 0.1 7.6e-66 222.2 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG42451.1 - 2.5e-19 69.7 0.0 5.7e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 CEG42451.1 - 2e-10 40.8 9.2 2e-10 40.8 9.2 3.4 2 1 1 3 3 3 1 HSA ResIII PF04851.15 CEG42451.1 - 2e-09 37.7 0.0 5.9e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG42451.1 - 0.00012 22.0 0.0 0.00084 19.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PAS PF00989.25 CEG42452.1 - 2.6e-102 336.7 7.4 2.2e-20 72.7 0.0 6.0 6 0 0 6 6 6 6 PAS fold PAS_4 PF08448.10 CEG42452.1 - 1.7e-69 231.0 0.0 4.6e-15 55.8 0.0 6.0 6 0 0 6 6 6 6 PAS fold PAS_9 PF13426.7 CEG42452.1 - 9.5e-60 199.3 15.5 3.5e-12 46.5 0.1 6.1 6 0 0 6 6 6 6 PAS domain PAS_3 PF08447.12 CEG42452.1 - 4.4e-31 107.0 0.0 1.2e-06 28.7 0.0 6.1 6 0 0 6 6 6 4 PAS fold PAS_8 PF13188.7 CEG42452.1 - 8.6e-21 73.5 1.6 0.0036 17.3 0.0 5.3 5 0 0 5 5 5 5 PAS domain PAS_10 PF13596.6 CEG42452.1 - 5.1e-15 56.0 8.1 2.9e-05 24.6 0.2 5.2 5 0 0 5 5 5 4 PAS domain PAS_7 PF12860.7 CEG42452.1 - 4.2e-08 33.3 18.1 0.33 11.1 0.2 8.2 6 4 0 6 6 6 4 PAS fold DUF3189 PF11385.8 CEG42452.1 - 0.00037 20.4 0.4 3.1 7.7 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3189) MRP-L51 PF10244.9 CEG42452.1 - 0.00048 20.3 0.3 24 5.2 0.0 4.3 4 0 0 4 4 4 0 Mitochondrial ribosomal subunit Peptidase_M7 PF02031.16 CEG42452.1 - 0.00092 19.3 0.0 26 4.9 0.0 4.3 4 0 0 4 4 4 0 Streptomyces extracellular neutral proteinase (M7) family Diphthami_syn_2 PF01902.17 CEG42452.1 - 0.004 16.7 0.4 6.6 6.2 0.0 3.4 3 0 0 3 3 3 1 Diphthamide synthase GARS_C PF02843.16 CEG42452.1 - 0.0052 17.0 0.7 17 5.8 0.0 4.9 5 0 0 5 5 5 0 Phosphoribosylglycinamide synthetase, C domain sCache_3_3 PF17202.4 CEG42452.1 - 0.015 15.7 9.3 67 4.0 0.0 6.0 4 1 1 5 5 5 0 Single cache domain 3 DUF2671 PF10877.8 CEG42452.1 - 0.29 11.0 1.3 87 3.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2671) rOmpB PF12334.8 CEG42453.1 - 0.19 11.2 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Yae1_N PF09811.9 CEG42454.1 - 7.1e-06 25.6 4.9 1.3e-05 24.8 4.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.9 CEG42454.1 - 0.0068 16.8 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 CCT PF06203.14 CEG42455.1 - 6.2e-14 51.8 7.1 6.2e-14 51.8 7.1 1.6 2 0 0 2 2 2 1 CCT motif DHC PF09626.10 CEG42455.1 - 0.063 14.1 0.3 1.1 10.2 0.0 2.1 2 0 0 2 2 2 0 Dihaem cytochrome c DUF16 PF01519.16 CEG42455.1 - 0.099 13.1 0.1 0.5 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4472 PF14739.6 CEG42455.1 - 0.12 13.1 1.5 0.23 12.2 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Xin PF08043.12 CEG42455.1 - 0.23 11.1 1.0 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 Xin repeat adh_short PF00106.25 CEG42456.1 - 3.9e-59 199.4 3.3 4.6e-59 199.2 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG42456.1 - 7.1e-42 143.6 1.1 8.8e-42 143.3 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG42456.1 - 1e-19 71.1 0.5 1.3e-19 70.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEG42456.1 - 1.1e-06 28.0 1.0 1.8e-06 27.3 1.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CEG42456.1 - 2.8e-06 27.0 0.3 1.5e-05 24.6 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CEG42456.1 - 0.0002 21.0 1.4 0.58 9.7 2.2 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 CEG42456.1 - 0.00075 18.6 0.3 0.0014 17.7 0.3 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CEG42456.1 - 0.00094 18.7 0.2 0.0022 17.5 0.2 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CEG42456.1 - 0.0038 17.1 2.7 0.0058 16.5 2.7 1.4 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 CEG42456.1 - 0.0039 16.8 0.2 0.0068 16.1 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.15 CEG42456.1 - 0.032 14.1 1.2 0.093 12.5 1.2 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.17 CEG42456.1 - 0.037 14.6 0.8 0.085 13.5 0.8 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CEG42456.1 - 0.047 13.6 1.3 0.086 12.7 1.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 CEG42456.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain FYVE PF01363.21 CEG42457.1 - 9e-16 57.8 14.7 3.1e-15 56.0 14.7 2.0 1 0 0 1 1 1 1 FYVE zinc finger MADF_DNA_bdg PF10545.9 CEG42457.1 - 0.086 13.2 0.4 0.28 11.5 0.4 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FYVE_2 PF02318.16 CEG42457.1 - 1.1 9.5 13.8 0.16 12.2 9.0 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger EssA PF10661.9 CEG42458.1 - 0.091 12.6 1.2 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA FYVE PF01363.21 CEG42460.1 - 2.7e-06 27.4 9.3 6.4e-06 26.2 9.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG42460.1 - 0.002 18.3 5.3 0.002 18.3 5.3 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Retrotran_gag_2 PF14223.6 CEG42461.1 - 8.6e-12 44.9 0.0 9.8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GHMP_kinases_N PF00288.26 CEG42462.1 - 5.2e-12 45.8 3.3 1e-11 44.9 0.3 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEG42462.1 - 2.6e-08 34.1 0.1 7.2e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Topoisom_I PF01028.20 CEG42463.1 - 4.1e-91 304.4 1.1 4.1e-91 304.4 1.1 2.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CEG42463.1 - 3e-83 278.5 0.6 3e-83 278.5 0.6 2.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CEG42463.1 - 2e-34 117.4 1.2 8.6e-34 115.3 1.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain T4SS PF07996.11 CEG42463.1 - 3.7 7.9 10.4 32 4.9 1.8 2.6 1 1 1 2 2 2 0 Type IV secretion system proteins Ank_2 PF12796.7 CEG42464.1 - 0.0085 16.7 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG42464.1 - 0.015 15.6 0.2 0.034 14.5 0.2 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG42464.1 - 0.037 14.6 0.2 0.82 10.3 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) FIST PF08495.10 CEG42466.1 - 1.1e-22 80.8 0.6 2.4e-22 79.8 0.6 1.6 1 0 0 1 1 1 1 FIST N domain FYVE PF01363.21 CEG42466.1 - 1.6e-12 47.4 13.9 3.4e-12 46.3 13.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG42466.1 - 0.031 14.5 10.5 0.029 14.6 8.5 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger FIST_C PF10442.9 CEG42466.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FIST C domain zf-RING_2 PF13639.6 CEG42466.1 - 1 9.8 13.0 2.6 8.5 13.0 1.8 1 0 0 1 1 1 0 Ring finger domain DUF2053 PF09767.9 CEG42469.1 - 0.053 13.7 0.1 0.057 13.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) IPK PF03770.16 CEG42473.1 - 2.2e-46 158.2 0.0 2.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase L27_1 PF09058.10 CEG42473.1 - 0.031 14.2 0.0 0.22 11.6 0.0 2.2 3 0 0 3 3 3 0 L27_1 SapB_2 PF03489.17 CEG42474.1 - 1.2e-22 79.7 34.2 0.00018 21.6 0.7 10.7 10 0 0 10 10 10 7 Saposin-like type B, region 2 TPR_9 PF13371.6 CEG42474.1 - 0.00087 19.4 0.1 0.75 10.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat SapB_1 PF05184.15 CEG42474.1 - 0.095 12.7 26.3 0.51 10.4 0.0 8.0 7 1 0 7 7 7 0 Saposin-like type B, region 1 DUF2200 PF09966.9 CEG42474.1 - 0.21 11.7 1.0 3.9 7.7 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) Thioredoxin_3 PF13192.6 CEG42474.1 - 2.8 8.1 12.1 6.3 6.9 0.1 5.6 6 0 0 6 6 6 0 Thioredoxin domain eRF1_3 PF03465.15 CEG42475.1 - 3.6e-07 30.6 0.0 4.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 eRF1 domain 3 APP_E2 PF12925.7 CEG42475.1 - 0.066 12.9 0.1 0.072 12.8 0.1 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein tRNA_int_endo PF01974.17 CEG42476.1 - 5.1e-23 80.9 0.1 9.8e-23 80.0 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Myb_DNA-bind_2 PF08914.11 CEG42477.1 - 1.8e-12 47.3 1.7 8.8e-12 45.0 0.6 2.5 2 0 0 2 2 2 1 Rap1 Myb domain BRCT_2 PF16589.5 CEG42477.1 - 5.3e-10 39.6 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CEG42477.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UBA PF00627.31 CEG42477.1 - 0.11 12.4 0.4 0.27 11.2 0.4 1.7 1 0 0 1 1 1 0 UBA/TS-N domain TRM13 PF05206.14 CEG42478.1 - 2.8e-62 210.6 0.1 2.6e-61 207.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase TRM13 TFIID-31kDa PF02291.15 CEG42478.1 - 1.9e-37 128.0 0.7 3.8e-37 127.0 0.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit zf-TRM13_CCCH PF11722.8 CEG42478.1 - 2.3e-09 36.9 1.6 2.3e-09 36.9 1.6 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CEG42478.1 - 1.2e-08 34.6 0.4 2.8e-08 33.5 0.4 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Histone PF00125.24 CEG42478.1 - 0.007 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEG42478.1 - 0.0085 16.5 0.1 0.027 14.8 0.1 1.8 1 0 0 1 1 1 1 CENP-S protein Methyltransf_32 PF13679.6 CEG42478.1 - 0.013 15.5 0.1 0.099 12.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain CENP-T_C PF15511.6 CEG42478.1 - 0.029 14.5 0.2 0.07 13.3 0.2 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold UPF0029 PF01205.19 CEG42479.1 - 6.7e-35 119.6 0.0 9.8e-35 119.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CEG42479.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain Arginase PF00491.21 CEG42480.1 - 5.1e-69 232.9 0.0 6.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family Vps51 PF08700.11 CEG42480.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 Cyt-b5 PF00173.28 CEG42481.1 - 3.1e-12 46.5 0.0 6.7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 CEG42481.1 - 0.037 14.3 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF3181 PF11378.8 CEG42481.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Rhodanese PF00581.20 CEG42481.1 - 0.14 12.7 0.0 3.9 8.0 0.0 2.4 1 1 1 2 2 2 0 Rhodanese-like domain TNFR_c6 PF00020.18 CEG42483.1 - 0.0013 19.1 0.2 0.0017 18.7 0.2 1.2 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region CD36 PF01130.21 CEG42484.1 - 5e-49 167.1 0.0 9.4e-48 162.9 0.0 2.1 1 1 0 1 1 1 1 CD36 family MCU PF04678.13 CEG42485.1 - 1e-31 110.4 0.1 1.7e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 CEG42485.1 - 5.5e-06 26.3 0.1 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain DUF2244 PF10003.9 CEG42485.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) TACC_C PF05010.14 CEG42487.1 - 0.12 12.2 0.3 0.14 12.0 0.3 1.0 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Retrotran_gag_2 PF14223.6 CEG42488.1 - 5.8e-06 26.0 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4611 PF15387.6 CEG42488.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Retrotrans_gag PF03732.17 CEG42488.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein Pep1_7 PF17232.2 CEG42490.1 - 0.21 12.0 2.5 0.44 11.0 2.5 1.5 1 0 0 1 1 1 0 Elicitor peptide 1-7 FAM76 PF16046.5 CEG42490.1 - 0.22 10.9 6.1 0.32 10.3 6.1 1.1 1 0 0 1 1 1 0 FAM76 protein MRI PF15325.6 CEG42490.1 - 0.23 12.6 1.7 0.58 11.3 1.7 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection TMEM192 PF14802.6 CEG42490.1 - 0.29 10.2 0.6 0.45 9.6 0.6 1.2 1 0 0 1 1 1 0 TMEM192 family bZIP_2 PF07716.15 CEG42490.1 - 0.35 11.0 18.3 0.067 13.3 7.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 CEG42490.1 - 3.6 7.8 18.2 0.49 10.5 11.6 2.2 1 1 1 2 2 2 0 bZIP transcription factor CPSase_L_D2 PF02786.17 CEG42492.1 - 3.5e-75 252.1 0.0 5.4e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEG42492.1 - 9.9e-44 148.4 0.5 3.9e-43 146.5 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEG42492.1 - 9.7e-36 122.2 0.0 2e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEG42492.1 - 3.8e-15 55.5 0.4 8.3e-15 54.4 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEG42492.1 - 1.5e-11 44.2 0.0 3.5e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEG42492.1 - 1.9e-10 40.6 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEG42492.1 - 3.2e-07 30.1 0.0 0.0039 17.0 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CEG42492.1 - 3.6e-05 23.9 0.0 6.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CEG42492.1 - 0.00047 20.0 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 CEG42492.1 - 0.0014 18.3 0.0 0.0066 16.1 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 CEG42492.1 - 0.011 15.0 0.1 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp MULE PF10551.9 CEG42493.1 - 0.043 14.2 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 MULE transposase domain AMP-binding PF00501.28 CEG42494.1 - 4.8e-77 259.3 0.0 6.7e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CEG42494.1 - 2.7e-63 213.6 0.0 4.2e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Thioesterase PF00975.20 CEG42494.1 - 3.2e-23 83.0 0.0 8e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Epimerase PF01370.21 CEG42494.1 - 9.9e-13 48.1 0.0 3.4e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 CEG42494.1 - 4e-09 37.3 0.0 1.4e-08 35.6 0.0 2.0 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 CEG42494.1 - 1.6e-08 34.7 0.1 6.1e-08 32.9 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 CEG42494.1 - 3.1e-07 30.1 0.0 5.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CEG42494.1 - 7.6e-07 28.4 0.0 1.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 CEG42494.1 - 3.4e-05 24.6 0.1 0.00018 22.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CEG42494.1 - 0.0067 16.3 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 CEG42494.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 CEG42494.1 - 0.024 14.3 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CEG42494.1 - 0.048 13.3 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 CEG42494.1 - 0.085 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 CEG42494.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acyltransferase PF01553.21 CEG42495.1 - 1.2e-20 73.5 0.0 2.2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CEG42495.1 - 2.3e-16 59.6 0.0 4.4e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus CRT-like PF08627.10 CEG42496.1 - 7e-121 403.3 18.4 8e-121 403.1 18.4 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CEG42496.1 - 4e-05 23.0 15.0 0.00016 21.0 15.2 2.0 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 CEG42496.1 - 0.00083 18.9 6.8 0.00083 18.9 6.8 2.0 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 CEG42496.1 - 3.6 7.8 33.4 0.27 11.4 13.8 3.6 1 1 2 3 3 3 0 EamA-like transporter family zf-CCCH PF00642.24 CEG42497.1 - 2.3e-14 52.8 13.7 1.9e-07 30.8 1.6 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG42497.1 - 2.7e-08 33.4 16.2 4.7e-05 23.1 3.1 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEG42497.1 - 5.4e-08 32.6 21.5 5.9e-05 23.0 5.0 2.7 3 0 0 3 3 2 2 Zinc finger domain zf-met PF12874.7 CEG42497.1 - 3.8e-06 27.1 5.7 5.2e-06 26.7 0.9 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEG42497.1 - 4.9e-05 23.5 7.6 0.00014 22.1 2.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEG42497.1 - 5.6e-05 23.4 8.8 0.0063 16.8 2.5 2.7 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CEG42497.1 - 0.00016 22.0 0.1 0.00016 22.0 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Torus PF16131.5 CEG42497.1 - 0.0034 18.1 2.5 0.0034 18.1 2.5 2.8 2 1 1 3 3 2 2 Torus domain zf-C2H2 PF00096.26 CEG42497.1 - 0.011 16.2 3.7 0.2 12.2 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type XOO_2897-deam PF14440.6 CEG42497.1 - 0.048 13.8 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase zf-C2H2_4 PF13894.6 CEG42497.1 - 0.076 13.9 4.0 0.43 11.6 0.1 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger zf-CCCH_2 PF14608.6 CEG42497.1 - 0.12 12.9 0.3 0.12 12.9 0.3 3.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-C2H2_6 PF13912.6 CEG42497.1 - 0.45 10.6 3.7 0.34 11.0 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF87 PF01935.17 CEG42497.1 - 1.2 9.1 6.0 0.2 11.7 1.5 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain zf-CCCH_3 PF15663.5 CEG42497.1 - 1.6 9.0 12.0 2.1 8.6 7.5 3.0 1 1 1 2 2 2 0 Zinc-finger containing family DUF1840 PF08895.11 CEG42497.1 - 2.7 8.4 5.4 1.5 9.2 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Arf PF00025.21 CEG42498.1 - 7.8e-45 152.4 0.1 1.3e-44 151.7 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Phosducin PF02114.16 CEG42498.1 - 4.8e-15 55.2 0.8 5.3e-14 51.8 0.8 2.0 1 1 0 1 1 1 1 Phosducin Roc PF08477.13 CEG42498.1 - 8.3e-12 45.4 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG42498.1 - 2.7e-10 40.1 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEG42498.1 - 7.7e-09 35.6 0.0 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEG42498.1 - 9e-09 34.9 1.8 9.1e-06 25.1 0.0 2.9 2 2 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEG42498.1 - 7.3e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG42498.1 - 7.4e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEG42498.1 - 2.8e-05 23.7 0.0 0.00044 19.8 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CEG42498.1 - 0.0017 18.0 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CEG42498.1 - 0.042 13.4 1.6 0.44 10.1 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 CEG42498.1 - 0.13 12.3 1.7 18 5.3 0.1 3.3 3 1 0 3 3 3 0 Dynamin family ATP-synt_D PF01813.17 CEG42502.1 - 6.3e-63 212.2 6.1 8.2e-63 211.8 6.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF573 PF04504.14 CEG42502.1 - 0.14 12.8 1.5 0.49 11.1 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF573 RabGAP-TBC PF00566.18 CEG42503.1 - 2.7e-22 79.5 1.3 1.9e-21 76.7 1.3 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MyTH4 PF00784.17 CEG42504.1 - 3.2e-23 82.3 0.1 7.1e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 CEG42504.1 - 4.5e-13 49.6 0.1 1.2e-12 48.2 0.1 1.7 1 0 0 1 1 1 1 FERM central domain RA PF00788.23 CEG42504.1 - 0.00012 22.7 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 CEG42504.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain DUF4533 PF15047.6 CEG42505.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) SURNod19 PF07712.12 CEG42506.1 - 0.1 11.3 4.9 0.11 11.3 4.9 1.1 1 0 0 1 1 1 0 Stress up-regulated Nod 19 Keratin_2_head PF16208.5 CEG42506.1 - 0.34 11.1 16.6 0.38 10.9 16.6 1.1 1 0 0 1 1 1 0 Keratin type II head VGCC_beta4Aa_N PF12052.8 CEG42507.1 - 0.22 11.6 0.1 0.37 10.9 0.1 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal BP28CT PF08146.12 CEG42508.1 - 1.3e-43 148.6 4.0 1.9e-43 148.1 0.9 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CEG42508.1 - 1.5e-20 73.7 3.0 1.5e-20 73.7 3.0 5.4 3 1 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CEG42508.1 - 3.8e-09 36.8 5.4 0.98 9.9 0.0 6.7 6 0 0 6 6 6 4 HEAT repeats HEAT PF02985.22 CEG42508.1 - 0.00098 19.2 9.8 0.19 12.1 0.2 6.9 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 CEG42508.1 - 0.013 16.0 9.9 2.4 8.8 0.0 7.1 8 0 0 8 8 8 0 HEAT-like repeat DUF3361 PF11841.8 CEG42508.1 - 0.17 11.8 4.1 0.26 11.2 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) HMGL-like PF00682.19 CEG42509.1 - 9.9e-58 195.8 0.0 1.1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PRA-PH PF01503.17 CEG42509.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Snf7 PF03357.21 CEG42510.1 - 1e-25 90.3 13.3 1.5e-25 89.8 13.3 1.2 1 0 0 1 1 1 1 Snf7 DUF21 PF01595.20 CEG42511.1 - 4.4e-29 101.4 0.2 6.6e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CEG42511.1 - 2e-07 31.3 2.5 0.0018 18.7 0.2 3.2 2 1 0 2 2 2 2 CBS domain Pyr_redox_2 PF07992.14 CEG42514.1 - 6.4e-30 104.4 0.4 7.3e-29 100.9 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CEG42514.1 - 1.3e-21 76.4 0.2 2.5e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 CEG42514.1 - 8.5e-09 35.1 0.7 0.048 12.9 0.1 4.1 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG42514.1 - 1e-08 35.3 0.0 8.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEG42514.1 - 6e-08 33.1 1.1 0.00011 22.7 0.2 3.4 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEG42514.1 - 4.2e-07 29.0 0.0 0.00015 20.6 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 CEG42514.1 - 8.7e-07 28.8 2.2 0.00038 20.1 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CEG42514.1 - 1.7e-06 27.6 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 CEG42514.1 - 1.2e-05 24.9 0.2 7.5e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEG42514.1 - 1.3e-05 24.5 0.3 0.00056 19.1 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 CEG42514.1 - 0.00026 20.2 0.1 0.032 13.3 0.1 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 CEG42514.1 - 0.00064 19.0 0.1 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CEG42514.1 - 0.00075 19.9 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CEG42514.1 - 0.0014 17.9 0.8 0.0028 16.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CEG42514.1 - 0.003 16.9 0.0 0.83 8.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CEG42514.1 - 0.0056 16.7 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 CEG42514.1 - 0.015 14.3 0.0 0.76 8.8 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 CEG42514.1 - 0.021 14.8 0.0 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 CEG42514.1 - 0.04 12.3 0.0 0.42 9.0 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like TrkA_N PF02254.18 CEG42514.1 - 0.076 13.3 0.0 21 5.4 0.0 2.8 3 0 0 3 3 2 0 TrkA-N domain YjeF_N PF03853.15 CEG42514.1 - 0.18 11.7 0.5 2.3 8.1 0.0 2.3 1 1 1 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 CEG42514.1 - 0.37 10.6 2.2 0.5 10.2 0.1 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cep57_CLD_2 PF14197.6 CEG42515.1 - 0.075 13.1 5.1 9.6 6.4 0.2 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 CEG42515.1 - 0.13 12.4 3.9 3.6 7.7 0.7 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DMPK_coil PF08826.10 CEG42515.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like FAD_SOX PF18371.1 CEG42516.1 - 0.14 12.5 0.2 24 5.4 0.0 3.2 2 2 1 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HSP70 PF00012.20 CEG42522.1 - 6.3e-45 153.5 3.5 7.1e-45 153.3 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein HTH_psq PF05225.16 CEG42524.1 - 7.6e-06 25.6 0.3 1.5e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEG42524.1 - 0.013 15.6 0.2 0.023 14.8 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CEG42524.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_35 PF13693.6 CEG42524.1 - 0.088 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ThiF PF00899.21 CEG42526.1 - 4.7e-92 307.8 0.0 4e-63 213.0 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CEG42526.1 - 2.1e-70 237.5 0.8 3.6e-70 236.8 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 CEG42526.1 - 2.6e-19 69.2 0.0 1.3e-18 66.9 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 CEG42526.1 - 4.2e-07 30.1 0.9 1.5e-06 28.3 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 CEG42526.1 - 0.0012 19.5 0.1 0.073 13.8 0.1 2.6 1 1 0 1 1 1 1 Ubiquitin fold domain Tap-RNA_bind PF09162.10 CEG42526.1 - 0.014 15.2 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 Tap, RNA-binding WW PF00397.26 CEG42527.1 - 6.3e-09 35.8 3.5 2.1e-08 34.1 3.5 1.9 1 0 0 1 1 1 1 WW domain DnaJ_CXXCXGXG PF00684.19 CEG42527.1 - 0.85 10.0 11.2 3.8 8.0 11.2 2.1 1 1 0 1 1 1 0 DnaJ central domain GUCT PF08152.12 CEG42529.1 - 3e-24 85.1 0.0 5.9e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.31 CEG42529.1 - 0.035 14.4 0.1 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Plasmid_stab_B PF10784.9 CEG42531.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Plasmid stability protein DUF5320 PF17253.2 CEG42532.1 - 0.037 15.1 0.0 0.083 14.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Pkinase PF00069.25 CEG42535.1 - 2.5e-28 99.2 0.0 5.4e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42535.1 - 8.9e-11 41.6 0.0 3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase BH3 PF15285.6 CEG42535.1 - 0.087 12.6 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting DIOX_N PF14226.6 CEG42536.1 - 1e-07 32.7 0.0 5.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEG42536.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_1 PF00583.25 CEG42537.1 - 2.7e-11 43.7 0.0 3.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG42537.1 - 5.5e-11 42.5 0.1 7.8e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG42537.1 - 5.5e-10 39.5 0.1 8e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG42537.1 - 2e-06 27.7 0.1 3.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 CEG42537.1 - 0.0019 17.7 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CEG42537.1 - 0.0096 16.6 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEG42537.1 - 0.011 15.8 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 CEG42537.1 - 0.015 15.0 0.3 0.022 14.5 0.3 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_8 PF13523.6 CEG42537.1 - 0.016 14.9 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 CEG42539.1 - 1.9e-35 122.7 0.1 4.8e-35 121.4 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.25 CEG42539.1 - 1.9e-32 112.7 0.0 4e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CEG42539.1 - 1.1e-23 83.1 0.1 4.2e-10 39.6 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CEG42539.1 - 1.6e-15 57.1 0.0 7.5e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PP2C_2 PF13672.6 CEG42539.1 - 6.2e-05 22.7 0.0 0.00049 19.8 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Kinase-like PF14531.6 CEG42539.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Rav1p_C PF12234.8 CEG42540.1 - 4.2e-48 164.2 9.3 4.2e-48 164.2 9.3 2.1 3 0 0 3 3 3 1 RAVE protein 1 C terminal C2 PF00168.30 CEG42540.1 - 5.5e-07 29.8 0.0 0.0023 18.2 0.0 2.8 2 0 0 2 2 2 2 C2 domain Tyrosinase PF00264.20 CEG42541.1 - 1.5e-13 51.6 0.0 9.5e-13 48.9 0.0 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase TFIID_30kDa PF03540.13 CEG42544.1 - 1.5e-21 76.1 0.1 3.4e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit PLA2G12 PF06951.11 CEG42545.1 - 8e-17 61.7 15.1 1.3e-16 61.0 15.1 1.3 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Herpes_BBRF1 PF04793.12 CEG42545.1 - 0.076 12.0 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 BRRF1-like protein PPR_2 PF13041.6 CEG42546.1 - 8.8e-44 147.5 10.7 3.5e-12 46.3 0.0 9.2 5 3 4 9 9 9 7 PPR repeat family PPR PF01535.20 CEG42546.1 - 9.1e-37 122.8 17.6 5.4e-05 23.2 0.0 12.0 11 1 0 11 11 11 9 PPR repeat PPR_3 PF13812.6 CEG42546.1 - 1.4e-35 121.1 7.0 2.6e-06 27.4 0.0 7.9 6 2 2 8 8 8 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEG42546.1 - 5.6e-35 118.7 0.7 4.6e-06 26.2 0.0 10.0 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 CEG42546.1 - 1.1e-17 64.1 7.3 2.9e-08 33.4 0.0 4.3 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP FYVE PF01363.21 CEG42546.1 - 2.6e-09 37.1 14.5 6.6e-09 35.8 14.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 CEG42546.1 - 1.9e-05 25.3 0.0 8.4e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CEG42546.1 - 0.00069 20.0 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain EF-hand_7 PF13499.6 CEG42546.1 - 0.0064 16.9 0.5 4.3 7.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair Pentapeptide_4 PF13599.6 CEG42546.1 - 0.016 15.4 7.9 0.069 13.3 0.6 3.9 2 2 2 4 4 4 0 Pentapeptide repeats (9 copies) SlyX PF04102.12 CEG42547.1 - 3.8 8.2 5.8 47 4.7 0.9 3.0 2 0 0 2 2 2 0 SlyX Glyco_transf_8 PF01501.20 CEG42551.1 - 9.7e-05 22.0 0.0 0.00093 18.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CEG42551.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.32 CEG42552.1 - 5.4e-50 166.3 27.8 1.3e-08 35.3 1.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG42552.1 - 3e-16 59.5 0.0 0.079 13.3 0.0 6.8 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG42552.1 - 2.4e-05 23.4 3.7 2.8 6.8 0.4 5.0 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG42552.1 - 5.1e-05 22.1 4.2 0.31 9.6 0.3 4.9 1 1 3 4 4 4 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CEG42552.1 - 0.00042 20.3 0.0 4.1 7.3 0.0 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Fib_alpha PF08702.10 CEG42552.1 - 0.026 14.7 2.2 0.067 13.4 2.2 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 CEG42552.1 - 0.28 9.7 4.0 0.41 9.2 4.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PKcGMP_CC PF16808.5 CEG42552.1 - 0.35 10.8 4.2 7.4 6.5 0.6 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 CEG42552.1 - 0.89 10.2 4.4 3.2 8.4 1.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Macoilin PF09726.9 CEG42552.1 - 7.6 5.0 12.9 0.094 11.3 1.2 2.0 1 1 1 2 2 2 0 Macoilin family ALMT PF11744.8 CEG42553.1 - 6.5 5.5 11.1 4.7 5.9 0.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter RRF PF01765.19 CEG42554.1 - 4.8e-46 156.7 3.4 6.3e-46 156.3 3.4 1.1 1 0 0 1 1 1 1 Ribosome recycling factor YtxH PF12732.7 CEG42554.1 - 0.0094 16.5 2.1 0.022 15.3 2.1 1.6 1 0 0 1 1 1 1 YtxH-like protein Med7 PF05983.11 CEG42554.1 - 0.045 13.8 0.3 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 MED7 protein DctP PF03480.13 CEG42554.1 - 0.051 12.9 3.4 1.4 8.2 2.4 2.1 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 ATP-synt_B PF00430.18 CEG42554.1 - 0.055 13.6 5.3 0.033 14.3 3.4 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) HisKA_3 PF07730.13 CEG42554.1 - 0.11 13.0 3.2 10 6.8 1.4 2.7 2 1 1 3 3 3 0 Histidine kinase Lectin_N PF03954.14 CEG42554.1 - 0.15 11.8 0.7 0.23 11.2 0.7 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ribosomal_S20p PF01649.18 CEG42554.1 - 0.52 11.0 6.5 0.33 11.6 4.3 1.8 2 0 0 2 2 2 0 Ribosomal protein S20 MMS19_N PF14500.6 CEG42555.1 - 1.3e-74 251.1 2.6 1.3e-74 251.1 2.6 3.8 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CEG42555.1 - 1.9e-73 248.0 9.3 1.9e-73 248.0 9.3 2.7 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CEG42555.1 - 0.00033 21.1 9.4 0.1 13.1 0.1 6.7 6 0 0 6 6 6 1 HEAT-like repeat TetR_C_22 PF17928.1 CEG42555.1 - 0.048 14.0 0.1 0.31 11.4 0.1 2.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TAF6_C PF07571.13 CEG42555.1 - 0.052 13.9 1.9 0.83 10.0 0.0 3.7 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Mog1 PF04603.12 CEG42555.1 - 0.19 12.1 0.6 15 6.0 0.0 3.1 2 1 1 3 3 3 0 Ran-interacting Mog1 protein HEAT PF02985.22 CEG42555.1 - 0.23 11.8 14.6 4.5 7.8 0.1 7.6 7 0 0 7 7 7 0 HEAT repeat DOG1 PF14144.6 CEG42556.1 - 0.01 16.1 0.4 0.019 15.2 0.4 1.5 1 0 0 1 1 1 0 Seed dormancy control VWA_3 PF13768.6 CEG42556.1 - 0.058 13.3 0.7 0.08 12.9 0.7 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Casc1_N PF15927.5 CEG42558.1 - 0.0035 17.1 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 Cancer susceptibility candidate 1 N-terminus NDUF_B7 PF05676.13 CEG42558.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ubiquitin PF00240.23 CEG42558.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Rep_fac_C PF08542.11 CEG42562.1 - 1.6e-22 79.7 0.0 3.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CEG42562.1 - 3.9e-14 52.8 0.2 1.1e-11 44.8 0.2 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CEG42562.1 - 7.9e-14 52.2 0.1 1.2e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEG42562.1 - 2.4e-07 30.8 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CEG42562.1 - 1.8e-06 28.4 0.2 0.00022 21.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CEG42562.1 - 1.4e-05 25.2 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEG42562.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CEG42562.1 - 2e-05 24.9 0.3 0.02 15.2 0.1 2.3 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEG42562.1 - 2.8e-05 23.6 0.2 0.00073 19.0 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CEG42562.1 - 0.00024 21.0 0.1 0.00045 20.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG42562.1 - 0.00045 20.6 1.0 0.0016 18.8 1.2 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEG42562.1 - 0.00046 20.0 0.1 0.0014 18.4 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CEG42562.1 - 0.00057 19.5 0.2 0.0037 16.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEG42562.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CEG42562.1 - 0.0012 18.6 0.7 0.0034 17.1 0.7 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEG42562.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CEG42562.1 - 0.0025 18.1 0.0 0.0068 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_3 PF07726.11 CEG42562.1 - 0.004 17.0 0.1 0.0067 16.3 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG42562.1 - 0.0044 17.5 0.1 0.014 15.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CEG42562.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 CEG42562.1 - 0.0084 16.6 0.0 0.02 15.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CEG42562.1 - 0.0088 15.1 0.1 0.018 14.0 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 CEG42562.1 - 0.0097 15.6 0.1 0.021 14.6 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 CEG42562.1 - 0.011 15.1 0.2 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CEG42562.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 CEG42562.1 - 0.023 14.5 0.7 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.13 CEG42562.1 - 0.04 13.1 0.1 0.061 12.5 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 CEG42562.1 - 0.053 13.7 0.1 0.1 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 CEG42562.1 - 0.056 12.9 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CEG42562.1 - 0.064 13.3 0.1 6 6.8 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CEG42562.1 - 0.068 13.1 0.2 0.29 11.0 0.1 2.0 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 CEG42562.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase MCM PF00493.23 CEG42562.1 - 0.1 11.6 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain DNA_pol3_delta PF06144.13 CEG42562.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_28 PF13521.6 CEG42562.1 - 0.14 12.4 0.2 0.3 11.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain DUF4586 PF15239.6 CEG42563.1 - 1.6e-58 199.3 4.4 1.9e-58 199.1 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkr1 PF08636.10 CEG42565.1 - 6.8e-12 45.3 4.1 8.2e-12 45.1 4.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 7TMR-DISM_7TM PF07695.11 CEG42565.1 - 0.003 17.5 3.2 0.0036 17.2 3.2 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling 7TM_GPCR_Srsx PF10320.9 CEG42565.1 - 0.0054 16.1 1.7 0.0065 15.9 1.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx YfhO PF09586.10 CEG42565.1 - 0.013 13.8 0.4 0.013 13.8 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SIT PF15330.6 CEG42565.1 - 2.9 8.4 0.0 2.9 8.4 0.0 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Got1 PF04178.12 CEG42566.1 - 3e-30 104.9 15.3 4.1e-30 104.5 15.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Pex24p PF06398.11 CEG42566.1 - 0.3 10.0 4.4 0.41 9.6 4.4 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2157 PF09925.9 CEG42566.1 - 3.1 7.6 8.0 0.48 10.2 1.6 2.5 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) Nup160 PF11715.8 CEG42567.1 - 2.1e-20 72.9 3.7 2.1e-20 72.9 3.7 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 CBF PF03914.17 CEG42568.1 - 8.8e-58 195.1 0.3 8.8e-58 195.1 0.3 3.0 3 1 0 3 3 3 2 CBF/Mak21 family AAA_22 PF13401.6 CEG42568.1 - 0.21 11.9 3.7 3.1 8.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain GlutR_dimer PF00745.20 CEG42568.1 - 3.1 8.3 7.6 2.9 8.4 0.3 3.9 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Acetate_kinase PF00871.17 CEG42569.1 - 5.7e-137 456.6 0.2 6.6e-137 456.4 0.2 1.0 1 0 0 1 1 1 1 Acetokinase family DUF3972 PF13118.6 CEG42572.1 - 0.0073 16.7 0.4 0.0076 16.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) Glucan_synthase PF02364.15 CEG42572.1 - 0.014 13.6 0.1 0.016 13.4 0.1 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component MBF1 PF08523.10 CEG42573.1 - 5.9e-18 65.1 3.7 1.1e-17 64.2 3.5 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CEG42573.1 - 2.8e-11 43.3 0.3 4.1e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CEG42573.1 - 0.00095 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CEG42573.1 - 0.02 14.9 0.4 0.037 14.0 0.1 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain XLF PF09302.11 CEG42573.1 - 0.096 12.8 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TRAP-gamma PF07074.12 CEG42573.1 - 0.12 11.9 0.6 0.16 11.5 0.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) MqsA_antitoxin PF15731.5 CEG42573.1 - 0.15 12.2 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA LSM PF01423.22 CEG42574.1 - 3.6e-21 74.6 0.4 4.4e-21 74.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain Gar1 PF04410.14 CEG42575.1 - 2.1e-34 118.5 0.0 2.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Mannosyl_trans3 PF11051.8 CEG42579.1 - 1.5e-35 122.9 0.2 5.8e-35 121.0 0.2 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative DUF5315 PF17242.2 CEG42579.1 - 0.2 11.5 0.1 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) AA_permease_2 PF13520.6 CEG42580.1 - 1.3e-30 106.6 29.7 1.9e-30 106.0 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG42580.1 - 3.3e-13 49.1 28.0 8.7e-12 44.4 28.0 2.1 1 1 0 1 1 1 1 Amino acid permease zf-C3HC4_3 PF13920.6 CEG42583.1 - 4.3e-11 42.5 12.6 4.3e-11 42.5 12.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 CEG42583.1 - 2.5e-10 40.8 0.4 1.3e-05 25.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CEG42583.1 - 5.9e-09 36.0 0.1 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEG42583.1 - 1.1e-07 32.0 1.4 6e-05 23.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG42583.1 - 4.5e-05 23.9 0.3 0.0011 19.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 CEG42583.1 - 4.9e-05 23.1 12.1 0.00018 21.3 10.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Ank_3 PF13606.6 CEG42583.1 - 7.2e-05 22.9 0.0 0.26 12.0 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat zf-RING_2 PF13639.6 CEG42583.1 - 0.00037 20.8 13.0 0.00037 20.8 13.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG42583.1 - 0.0048 16.7 15.1 0.012 15.4 13.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C4H2 PF10146.9 CEG42583.1 - 0.3 11.4 5.3 0.48 10.7 5.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein GNAT_like PF18407.1 CEG42583.1 - 0.31 11.4 3.5 0.73 10.2 0.2 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain zf-RING_5 PF14634.6 CEG42583.1 - 1 9.4 16.3 0.49 10.4 13.6 1.9 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 CEG42583.1 - 2.3 8.3 10.1 63 3.7 10.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon Acyltransferase PF01553.21 CEG42586.1 - 0.025 14.2 0.2 0.028 14.1 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase HtrL_YibB PF09612.10 CEG42587.1 - 0.0011 18.6 0.8 0.0016 18.0 0.5 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Pkinase PF00069.25 CEG42588.1 - 3.7e-56 190.4 0.0 1.5e-52 178.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42588.1 - 3.7e-26 92.0 0.0 5.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42588.1 - 1.8e-05 24.2 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG42588.1 - 7.6e-05 21.7 0.2 0.00013 20.9 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG42588.1 - 0.00048 19.5 0.1 0.0008 18.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG42588.1 - 0.006 16.5 0.5 0.018 15.0 0.5 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RNaseH_like PF04308.12 CEG42589.1 - 0.049 13.5 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease H-like RPGR1_C PF18111.1 CEG42589.1 - 0.056 13.3 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Retinitis pigmentosa G-protein regulator interacting C-terminal OSTMP1 PF09777.9 CEG42591.1 - 0.041 13.3 0.5 0.056 12.8 0.5 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor CT_A_B PF02626.15 CEG42592.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B RNA_pol_Rpo13 PF12136.8 CEG42592.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain cwf21 PF08312.12 CEG42593.1 - 0.018 15.2 0.1 0.023 14.8 0.1 1.1 1 0 0 1 1 1 0 cwf21 domain DUF2458 PF10454.9 CEG42593.1 - 0.065 12.9 0.0 0.072 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Pectinesterase PF01095.19 CEG42594.1 - 1.8e-37 128.7 5.0 2.7e-37 128.1 5.0 1.1 1 0 0 1 1 1 1 Pectinesterase ACT_7 PF13840.6 CEG42594.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain Phage_holin_2_4 PF16082.5 CEG42596.1 - 0.12 12.1 0.3 0.14 11.9 0.3 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4307 PF14155.6 CEG42596.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) PetG PF02529.15 CEG42596.1 - 0.44 10.4 1.6 0.65 9.9 1.6 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 SIT PF15330.6 CEG42597.1 - 0.031 14.7 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3311 PF11755.8 CEG42597.1 - 0.34 10.9 1.8 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) TRP PF06011.12 CEG42600.1 - 8.4e-26 90.7 25.5 2.5e-25 89.1 14.5 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel Ammonium_transp PF00909.21 CEG42601.1 - 1.3e-62 211.8 19.5 1.6e-62 211.5 19.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UNC-79 PF14776.6 CEG42601.1 - 0.033 12.9 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 GAF PF01590.26 CEG42603.1 - 1.3e-07 32.3 0.1 1.5e-07 32.1 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEG42603.1 - 3.5e-05 24.1 0.0 3.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CEG42603.1 - 9.8e-05 22.7 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain E3_UFM1_ligase PF09743.9 CEG42604.1 - 1.6e-78 264.1 2.2 3.4e-78 263.0 2.2 1.6 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Rad9 PF04139.13 CEG42605.1 - 3e-41 141.5 6.3 3.9e-41 141.1 6.3 1.2 1 0 0 1 1 1 1 Rad9 SLAIN PF15301.6 CEG42606.1 - 0.034 13.4 1.1 0.038 13.3 1.1 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family WD40 PF00400.32 CEG42607.1 - 1.6e-15 57.2 17.1 0.0014 19.4 0.1 10.0 9 0 0 9 9 9 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 CEG42607.1 - 2.3e-07 31.2 0.5 7.5e-07 29.5 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CEG42607.1 - 2.1e-06 27.4 2.9 2.5e-06 27.3 0.5 2.5 2 1 1 3 3 3 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 CEG42607.1 - 5.3e-06 26.6 4.4 1.4 9.3 0.0 5.4 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 CEG42607.1 - 6.1e-05 22.3 3.6 0.001 18.5 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CEG42607.1 - 6.4e-05 22.3 0.4 0.0002 20.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEG42607.1 - 0.00022 20.9 0.8 0.0079 16.1 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain Ge1_WD40 PF16529.5 CEG42607.1 - 0.0014 17.7 0.0 0.44 9.5 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG42607.1 - 0.036 12.7 1.7 0.082 11.5 0.6 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SHOCT PF09851.9 CEG42607.1 - 0.036 13.8 0.2 0.085 12.6 0.2 1.6 1 0 0 1 1 1 0 Short C-terminal domain RT_RNaseH_2 PF17919.1 CEG42608.1 - 0.06 13.4 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase UPF0203 PF05254.12 CEG42612.1 - 2.4e-10 40.5 6.0 5.1e-10 39.5 6.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Apolipoprotein PF01442.18 CEG42612.1 - 4.3e-08 33.3 9.4 6.2e-08 32.7 9.0 1.3 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CEG42612.1 - 1.4e-06 28.7 19.1 0.00069 20.1 3.5 3.5 1 1 2 3 3 3 3 YtxH-like protein ApoLp-III PF07464.11 CEG42612.1 - 0.00038 20.6 10.5 0.0034 17.5 5.6 2.3 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Senescence PF06911.12 CEG42612.1 - 0.0013 19.0 1.0 0.0017 18.7 1.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein Cmc1 PF08583.10 CEG42612.1 - 0.0036 17.3 2.5 0.24 11.4 0.2 2.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF883 PF05957.13 CEG42612.1 - 0.0041 17.7 18.9 0.75 10.4 5.7 3.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) CX9C PF16860.5 CEG42612.1 - 0.014 15.4 3.8 0.15 12.1 0.6 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RRF PF01765.19 CEG42612.1 - 0.019 14.9 18.6 0.057 13.4 7.1 2.2 1 1 1 2 2 2 0 Ribosome recycling factor Perilipin PF03036.16 CEG42612.1 - 0.023 13.7 5.0 0.025 13.6 4.1 1.4 1 1 1 2 2 2 0 Perilipin family Colicin_D PF11429.8 CEG42612.1 - 0.28 11.7 2.5 0.36 11.3 0.8 2.0 2 0 0 2 2 2 0 Colicin D Prominin PF05478.11 CEG42612.1 - 0.3 9.0 3.7 0.38 8.7 3.7 1.2 1 0 0 1 1 1 0 Prominin Ykof PF07615.11 CEG42612.1 - 0.31 11.5 2.7 1.9 9.1 0.3 2.8 2 1 0 2 2 2 0 YKOF-related Family Lant_dehydr_C PF14028.6 CEG42612.1 - 0.38 10.2 5.2 0.53 9.8 4.9 1.4 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term LEA_4 PF02987.16 CEG42612.1 - 0.97 9.6 17.1 8.4 6.6 0.7 3.7 1 1 1 3 3 3 0 Late embryogenesis abundant protein DUF948 PF06103.11 CEG42612.1 - 1.5 9.1 4.5 31 4.9 4.5 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 CEG42612.1 - 2.5 8.1 9.2 4 7.4 0.8 2.8 2 1 2 4 4 4 0 Apolipoprotein O Phasin PF05597.11 CEG42612.1 - 2.6 8.1 17.2 2 8.4 5.0 3.1 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.7 CEG42612.1 - 3 7.1 7.0 1.2 8.4 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) NDUF_B7 PF05676.13 CEG42612.1 - 8.2 6.2 8.8 0.94 9.2 0.9 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PH PF00169.29 CEG42613.1 - 6.5e-15 55.5 0.3 2.3e-09 37.7 0.0 2.7 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 CEG42613.1 - 9.9e-07 29.0 0.0 7.3e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CEG42613.1 - 2.3e-05 24.8 0.9 0.009 16.4 0.2 2.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CEG42613.1 - 0.033 14.5 0.0 15 6.0 0.0 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 CEG42613.1 - 0.11 12.8 0.2 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_28 PF03033.20 CEG42615.1 - 8.1e-25 87.5 0.3 8.3e-17 61.5 0.2 4.5 4 1 0 4 4 4 3 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CEG42615.1 - 2.1e-07 30.1 0.1 5.1e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 CEG42615.1 - 1.6e-06 28.3 0.0 3.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 CEG42615.1 - 0.00033 20.7 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 CEG42615.1 - 0.00043 20.1 0.2 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal FACT-Spt16_Nlob PF14826.6 CEG42615.1 - 0.2 11.5 0.1 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain SDF PF00375.18 CEG42616.1 - 1.2e-101 340.6 29.4 1.4e-101 340.4 29.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family RVT_2 PF07727.14 CEG42617.1 - 2e-29 103.0 0.0 3.1e-29 102.3 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 CEG42618.1 - 1.3e-19 71.3 5.7 2.1e-19 70.6 5.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 CEG42618.1 - 5.4e-06 26.2 5.4 2e-05 24.4 5.4 2.1 1 0 0 1 1 1 1 PAN domain DASH_Dad2 PF08654.10 CEG42618.1 - 0.11 12.9 0.1 8 6.9 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 PAN_3 PF08277.12 CEG42618.1 - 0.86 9.5 6.4 0.26 11.1 2.5 2.1 2 0 0 2 2 2 0 PAN-like domain CAP PF00188.26 CEG42619.1 - 2.9e-22 79.9 1.4 5.4e-22 79.0 1.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 CEG42619.1 - 5.7e-06 26.1 2.5 1.5e-05 24.8 2.5 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CEG42619.1 - 0.085 13.0 1.1 0.34 11.1 1.1 2.0 1 0 0 1 1 1 0 PAN-like domain RVT_2 PF07727.14 CEG42621.1 - 1.5e-46 159.0 0.0 1.8e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_2 PF13347.6 CEG42623.1 - 7.5e-09 34.6 11.9 7.5e-09 34.6 11.9 2.6 2 1 1 3 3 3 1 MFS/sugar transport protein PLDc_2 PF13091.6 CEG42624.1 - 1.4e-16 60.6 0.0 1.7e-13 50.6 0.2 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEG42624.1 - 3e-08 33.5 3.9 5.9e-05 23.1 0.3 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif FH2 PF02181.23 CEG42627.1 - 1.4e-94 317.3 1.3 1.4e-94 317.3 1.3 3.1 3 0 0 3 3 3 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG42627.1 - 2.8e-34 118.8 22.1 5.1e-12 46.5 2.4 5.5 6 0 0 6 6 6 3 Subunit CCDC53 of WASH complex FYVE PF01363.21 CEG42627.1 - 2.6e-09 37.1 10.5 2.6e-09 37.1 10.5 2.3 2 0 0 2 2 2 1 FYVE zinc finger zinc_ribbon_2 PF13240.6 CEG42627.1 - 2.4e-06 27.1 1.6 2.4e-06 27.1 1.6 2.7 3 0 0 3 3 3 1 zinc-ribbon domain FYVE_2 PF02318.16 CEG42627.1 - 1.1e-05 25.6 3.5 1.1e-05 25.6 3.5 3.5 4 0 0 4 4 4 1 FYVE-type zinc finger DZR PF12773.7 CEG42627.1 - 0.00025 21.0 0.3 0.00025 21.0 0.3 3.3 2 1 0 2 2 2 1 Double zinc ribbon ERM PF00769.19 CEG42627.1 - 0.12 12.1 27.5 0.25 11.1 2.5 3.4 3 0 0 3 3 3 0 Ezrin/radixin/moesin family zf-piccolo PF05715.13 CEG42627.1 - 3.1 8.0 14.3 0.32 11.2 6.4 2.7 2 1 0 2 2 2 0 Piccolo Zn-finger BLOC1_2 PF10046.9 CEG42627.1 - 9.3 6.6 13.0 2.7 8.4 3.4 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PH PF00169.29 CEG42628.1 - 3.2e-13 50.1 0.2 4.1e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG42628.1 - 2.4e-06 27.9 0.7 4.6e-05 23.8 0.7 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG42628.1 - 1.8e-05 24.9 0.5 3.4e-05 24.0 0.5 1.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CEG42628.1 - 0.027 14.3 0.2 0.053 13.3 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 CEG42628.1 - 0.027 14.8 0.5 3 8.2 0.5 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 CEG42628.1 - 0.03 14.7 0.0 0.048 14.0 0.0 1.4 1 1 0 1 1 1 0 Plant pleckstrin homology-like region Methyltransf_16 PF10294.9 CEG42629.1 - 3.8e-29 101.6 0.0 5.5e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG42629.1 - 0.00014 21.3 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG42629.1 - 0.0022 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG42629.1 - 0.0068 17.1 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG42629.1 - 0.0098 15.7 0.0 0.025 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.15 CEG42629.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.4 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 CEG42629.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 CEG42629.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SHMT PF00464.19 CEG42630.1 - 7.6e-199 660.3 0.0 8.8e-199 660.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CEG42630.1 - 0.00062 19.0 0.0 0.006 15.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II V-ATPase_H_C PF11698.8 CEG42631.1 - 0.0064 16.6 0.0 0.0072 16.4 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H T4_Rnl2_C PF18043.1 CEG42631.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal G6PD_C PF02781.16 CEG42632.1 - 1.1e-107 359.5 0.0 1.4e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEG42632.1 - 1.9e-55 188.2 0.0 2.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucan_synthase PF02364.15 CEG42635.1 - 6.9e-168 560.4 6.4 4e-149 498.3 4.8 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase component HECT PF00632.25 CEG42635.1 - 1.2e-37 130.1 0.0 2.6e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FKS1_dom1 PF14288.6 CEG42635.1 - 3.2e-28 98.7 0.4 2.1e-27 96.0 0.4 2.4 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NPCBM PF08305.11 CEG42635.1 - 6.4e-21 75.0 0.0 1.6e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 NPCBM/NEW2 domain SPRY PF00622.28 CEG42635.1 - 1.8e-14 53.9 0.1 3e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 SPRY domain F5_F8_type_C PF00754.25 CEG42635.1 - 2.1e-05 24.6 0.1 6.9e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 F5/8 type C domain UBA PF00627.31 CEG42635.1 - 2.4e-05 24.1 0.3 0.0019 18.0 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Laminin_G_3 PF13385.6 CEG42635.1 - 3.8e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Arm PF00514.23 CEG42635.1 - 0.0018 18.2 1.7 0.0048 16.9 0.2 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat zf-RanBP PF00641.18 CEG42635.1 - 0.077 12.3 3.6 0.18 11.2 3.6 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others AMP-binding PF00501.28 CEG42636.1 - 2e-20 72.8 0.0 5.3e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Bac_GH3_C PF18034.1 CEG42636.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial Glycosyl hydrolase family 3 C-terminal domain Ctf8 PF09696.10 CEG42637.1 - 1.3e-12 48.2 0.0 2e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Ctf8 ECH_1 PF00378.20 CEG42638.1 - 4.3e-35 121.2 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEG42638.1 - 1.7e-18 67.2 0.0 2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Baculo_PEP_C PF04513.12 CEG42639.1 - 0.035 14.1 12.5 0.53 10.3 5.5 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 CEG42639.1 - 0.32 10.7 15.7 7.6 6.3 6.4 3.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 CEG42639.1 - 0.35 11.3 37.9 0.91 9.9 17.4 2.3 1 1 1 2 2 2 0 Fez1 Cep57_MT_bd PF06657.13 CEG42639.1 - 0.72 10.3 20.3 6.4 7.3 2.7 4.2 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 UCH PF00443.29 CEG42639.1 - 2.9 7.3 6.9 8 5.9 6.6 1.9 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Peptidase_S46 PF10459.9 CEG42639.1 - 3.8 6.0 20.2 5.1 5.6 20.2 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3584 PF12128.8 CEG42639.1 - 4 4.8 34.9 6.2 4.2 34.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PDCD7 PF16021.5 CEG42640.1 - 1.2e-13 50.9 17.2 6.4e-09 35.4 0.1 2.1 2 0 0 2 2 2 2 Programmed cell death protein 7 eIF2A PF08662.11 CEG42641.1 - 5.6e-72 241.7 0.0 8.3e-69 231.4 0.0 2.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CEG42641.1 - 0.013 16.3 1.6 54 4.9 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Aminotran_3 PF00202.21 CEG42642.1 - 1.9e-51 175.0 0.0 1.6e-50 172.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 CEG42642.1 - 7.4e-19 68.4 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RVP_2 PF08284.11 CEG42644.1 - 7.2e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEG42644.1 - 1.2e-05 25.8 0.0 2.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG42644.1 - 1.8e-05 25.2 0.0 3.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A3 PF02160.15 CEG42644.1 - 0.0058 16.1 0.6 0.019 14.4 0.1 1.8 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) PTEN_C2 PF10409.9 CEG42645.1 - 9.5e-19 67.5 0.0 2.4e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CEG42645.1 - 9.7e-06 25.4 0.0 5.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG42645.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEG42645.1 - 0.015 15.2 0.9 0.028 14.4 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family KCNQC3-Ank-G_bd PF11956.8 CEG42645.1 - 0.075 13.3 2.6 0.37 11.1 0.8 2.8 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 ANAPC_CDC26 PF10471.9 CEG42645.1 - 0.3 11.9 5.1 1.6 9.6 5.1 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PTPlike_phytase PF14566.6 CEG42645.1 - 0.93 9.6 0.0 0.93 9.6 0.0 2.7 2 1 0 2 2 2 0 Inositol hexakisphosphate KH_8 PF17903.1 CEG42648.1 - 1.6e-05 24.9 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CEG42648.1 - 0.0056 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 KH domain rve PF00665.26 CEG42650.1 - 0.0085 16.3 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain zf-CCCH_4 PF18044.1 CEG42652.1 - 7.6e-09 35.2 4.0 1.5e-08 34.2 4.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CEG42652.1 - 4.4e-06 26.5 3.9 1e-05 25.3 3.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG42652.1 - 1.3e-05 25.1 5.3 2.6e-05 24.1 5.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CEG42652.1 - 0.017 15.8 0.5 0.035 14.8 0.5 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 CEG42652.1 - 0.03 14.8 4.3 0.05 14.1 4.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RseA_C PF03873.13 CEG42652.1 - 0.18 12.0 3.6 1.1 9.5 1.7 2.9 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain TMEM43 PF07787.12 CEG42653.1 - 1.7e-61 207.8 0.0 2.5e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 DUF2628 PF10947.8 CEG42653.1 - 0.6 10.5 4.4 2.5 8.5 4.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Pro_isomerase PF00160.21 CEG42654.1 - 9.6e-45 152.7 0.0 1.2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF667 PF05018.13 CEG42655.1 - 3.7e-28 98.5 0.1 9e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF667) WD40 PF00400.32 CEG42655.1 - 7.7e-23 80.4 15.7 0.00088 20.0 0.1 12.6 13 0 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG42655.1 - 1.7e-09 37.8 0.6 3.2 8.1 0.0 9.1 8 2 3 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CEG42655.1 - 0.16 11.5 0.3 2.5 7.6 0.0 3.0 4 0 0 4 4 4 0 PQQ-like domain ATP_synt_H PF05493.13 CEG42656.1 - 5e-14 52.5 8.7 5.9e-14 52.3 8.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Arm PF00514.23 CEG42657.1 - 3.5e-84 274.6 23.3 1.1e-12 47.5 0.0 9.0 7 2 2 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG42657.1 - 1.6e-20 73.2 2.0 8.1e-05 23.0 0.0 5.8 4 2 1 5 5 5 4 HEAT-like repeat Arm_3 PF16186.5 CEG42657.1 - 2.8e-19 68.4 0.5 5.6e-17 61.1 1.4 2.6 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CEG42657.1 - 6.2e-18 65.0 0.8 6.7e-06 26.4 0.0 6.5 3 2 1 6 6 6 3 HEAT repeats IBB PF01749.20 CEG42657.1 - 2.7e-15 56.6 2.1 6.6e-15 55.3 2.1 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 CEG42657.1 - 6.7e-14 50.8 5.5 0.024 14.9 0.1 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 CEG42657.1 - 9.3e-05 22.8 2.0 7.9 7.5 0.0 5.7 6 0 0 6 6 5 2 PBS lyase HEAT-like repeat NopRA1 PF16201.5 CEG42657.1 - 9.4e-05 22.1 0.0 3.2 7.3 0.0 3.9 2 1 1 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 DUF3361 PF11841.8 CEG42657.1 - 0.00011 22.2 0.5 0.04 13.9 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) Arm_2 PF04826.13 CEG42657.1 - 0.00023 20.7 0.3 0.88 9.0 0.1 3.8 3 1 1 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 CEG42657.1 - 0.0014 18.7 0.1 12 6.0 0.0 4.0 3 2 1 4 4 4 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 CEG42657.1 - 0.01 16.2 0.1 11 6.4 0.0 3.5 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mo25 PF08569.11 CEG42657.1 - 0.016 14.6 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Mo25-like CTNNBL PF08216.11 CEG42657.1 - 0.049 13.8 4.4 22 5.3 0.0 5.2 6 1 2 8 8 8 0 Catenin-beta-like, Arm-motif containing nuclear SPA PF08616.10 CEG42660.1 - 1.3e-29 102.4 0.0 3.9e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CEG42660.1 - 1.7e-14 54.4 0.2 1.5e-13 51.4 0.2 2.2 1 1 1 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 CEG42660.1 - 3.4e-13 49.8 0.0 1.3e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CEG42660.1 - 4.5e-11 42.1 0.2 0.00012 20.9 0.4 3.0 1 1 1 2 2 2 2 Transport protein Avl9 PIH1 PF08190.12 CEG42661.1 - 1.1e-22 80.3 0.6 2.8e-22 78.9 0.2 1.8 2 0 0 2 2 2 1 PIH1 N-terminal domain RsgI_N PF12791.7 CEG42661.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Chorismate_bind PF00425.18 CEG42662.1 - 9.1e-75 251.5 0.0 1.4e-60 205.0 0.0 2.3 1 1 1 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 CEG42662.1 - 1.6e-28 99.7 0.0 2.2e-27 96.0 0.0 2.6 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region DUF1484 PF07363.11 CEG42662.1 - 0.14 13.1 0.0 12 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) CCDC-167 PF15188.6 CEG42664.1 - 0.021 15.2 8.5 0.74 10.2 0.1 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3037 PF11236.8 CEG42664.1 - 0.041 14.3 0.8 2.3 8.6 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) SAM_Ste50p PF09235.10 CEG42664.1 - 0.1 12.8 0.6 0.4 10.9 0.1 2.3 3 0 0 3 3 3 0 Ste50p, sterile alpha motif AAA_23 PF13476.6 CEG42664.1 - 0.34 11.4 8.2 0.54 10.7 8.2 1.3 1 0 0 1 1 1 0 AAA domain ArfGap PF01412.18 CEG42665.1 - 5.1e-33 113.6 0.2 2.5e-32 111.4 0.2 2.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HMMR_C PF15908.5 CEG42665.1 - 0.023 15.0 2.1 0.023 15.0 2.1 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Armet PF10208.9 CEG42666.1 - 4.6e-24 85.0 9.8 7.9e-24 84.2 9.8 1.3 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CEG42666.1 - 0.00034 20.3 1.3 0.00083 19.0 0.1 2.1 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 CEG42666.1 - 0.00065 19.3 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain YhfH PF14149.6 CEG42666.1 - 0.97 9.5 5.4 1.7 8.7 0.4 2.8 3 0 0 3 3 3 0 YhfH-like protein RAMP4 PF06624.12 CEG42667.1 - 3.9e-20 71.7 0.1 4.2e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 NAD_binding_5 PF07994.12 CEG42668.1 - 4.4e-147 489.6 0.1 5.1e-147 489.4 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CEG42668.1 - 3.8e-48 162.3 0.6 7.2e-48 161.4 0.6 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Glyco_transf_64 PF09258.10 CEG42668.1 - 0.027 13.7 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain fn3 PF00041.21 CEG42669.1 - 8.1e-07 29.3 0.1 0.0097 16.2 0.1 3.1 3 0 0 3 3 3 2 Fibronectin type III domain DIM PF08194.12 CEG42669.1 - 0.15 12.3 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 DIM protein Ank_2 PF12796.7 CEG42670.1 - 5.4e-21 75.0 0.4 4.4e-15 56.0 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG42670.1 - 3.5e-18 65.4 3.9 1.9e-06 28.1 0.6 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG42670.1 - 8.8e-18 63.9 4.7 0.0001 22.6 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 CEG42670.1 - 5.1e-17 61.8 14.6 1.2e-16 60.6 14.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 CEG42670.1 - 1.7e-15 55.6 1.3 0.0092 16.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 CEG42670.1 - 1.4e-13 51.1 4.7 3.3e-08 33.9 0.0 5.4 5 2 2 7 7 7 3 Ankyrin repeats (many copies) CP_ATPgrasp_2 PF14403.6 CEG42670.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 FYVE_2 PF02318.16 CEG42670.1 - 0.15 12.3 12.1 0.84 9.9 12.0 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.25 CEG42671.1 - 1.1e-77 261.0 0.0 2.5e-77 259.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42671.1 - 4.6e-44 150.6 0.0 1.2e-43 149.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 CEG42671.1 - 2.3e-11 42.9 0.4 0.0094 16.1 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Arm PF00514.23 CEG42671.1 - 1.2e-09 37.8 3.0 0.014 15.4 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG42671.1 - 1.7e-08 34.8 0.0 0.00095 19.6 0.0 3.1 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 CEG42671.1 - 1.9e-06 27.4 0.0 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG42671.1 - 2.5e-05 23.3 0.0 5.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase HEAT_2 PF13646.6 CEG42671.1 - 3.1e-05 24.3 0.0 0.0016 18.8 0.0 3.6 3 1 1 4 4 3 1 HEAT repeats Haspin_kinase PF12330.8 CEG42671.1 - 0.00043 19.3 0.3 0.0012 17.9 0.3 1.7 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEG42671.1 - 0.0007 19.3 0.4 0.0025 17.4 0.4 1.9 1 1 0 1 1 1 1 RIO1 family NopRA1 PF16201.5 CEG42671.1 - 0.037 13.6 0.9 1.9 8.0 0.2 3.5 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 APH PF01636.23 CEG42671.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG42671.1 - 0.08 12.3 0.2 0.18 11.1 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3492 PF11997.8 CEG42673.1 - 0.0084 15.9 0.3 0.0091 15.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) HAD_2 PF13419.6 CEG42675.1 - 2.8e-18 66.6 0.0 1.9e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEG42675.1 - 4.6e-14 53.2 0.0 4.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG42675.1 - 1.3e-08 34.8 0.0 3.1e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 CEG42675.1 - 0.071 13.5 0.0 0.23 11.9 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase gp45-slide_C PF09116.10 CEG42677.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal DDE_1 PF03184.19 CEG42680.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease CPSase_L_D2 PF02786.17 CEG42683.1 - 5.6e-75 251.5 0.3 1.1e-74 250.5 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CEG42683.1 - 2.7e-67 226.4 0.0 4.1e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CEG42683.1 - 1.4e-38 131.8 0.1 9.3e-38 129.2 0.0 2.4 3 0 0 3 3 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEG42683.1 - 6e-30 103.5 0.0 1.5e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CEG42683.1 - 1.1e-27 97.3 0.0 1.9e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CEG42683.1 - 6.9e-15 54.6 4.2 1.4e-14 53.7 2.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEG42683.1 - 1.1e-09 38.1 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CEG42683.1 - 2.3e-09 36.9 0.4 0.0007 19.4 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CEG42683.1 - 6e-07 29.2 0.1 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEG42683.1 - 1.1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CEG42683.1 - 0.00024 21.8 0.1 0.39 11.4 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 CEG42683.1 - 0.00026 20.6 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 CEG42683.1 - 0.0024 17.3 0.3 0.0044 16.5 0.3 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 CEG42683.1 - 0.0054 16.0 0.3 0.21 10.8 0.1 2.6 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 CEG42683.1 - 0.018 15.0 0.3 0.055 13.4 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ntox43 PF15537.6 CEG42683.1 - 0.13 12.3 0.1 0.58 10.2 0.0 2.1 2 0 0 2 2 1 0 Bacterial toxin 43 Myosin_head PF00063.21 CEG42684.1 - 9.5e-208 691.7 0.2 9.5e-208 691.7 0.2 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CEG42684.1 - 7.3e-30 104.0 1.1 2e-29 102.6 1.1 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 CEG42684.1 - 0.0053 17.0 0.0 0.06 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG42684.1 - 0.023 15.1 0.0 0.072 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CEG42684.1 - 0.05 13.9 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEG42684.1 - 0.14 11.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FH2 PF02181.23 CEG42685.1 - 5.5e-54 183.7 10.5 1.3e-53 182.5 10.5 1.6 1 1 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG42685.1 - 1.4e-10 41.8 0.7 0.00012 22.5 0.0 2.7 2 0 0 2 2 2 2 Subunit CCDC53 of WASH complex PAZ PF02170.22 CEG42685.1 - 0.043 13.6 1.7 0.075 12.8 0.1 2.1 2 0 0 2 2 2 0 PAZ domain SAM_KSR1 PF13543.6 CEG42685.1 - 0.49 10.5 3.3 0.58 10.3 0.9 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 RXLR_WY PF18634.1 CEG42686.1 - 1.1e-11 44.4 0.4 0.0015 18.4 0.1 3.6 3 0 0 3 3 3 3 RXLR phytopathogen effector protein WY-domain DUF1057 PF06342.12 CEG42687.1 - 6.1e-20 71.4 0.0 1.2e-19 70.5 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 CEG42687.1 - 7e-10 39.0 0.5 3.7e-09 36.6 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG42687.1 - 6.3e-09 35.4 0.0 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG42687.1 - 2.4e-08 34.9 0.0 3.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CEG42687.1 - 0.0024 16.8 0.1 0.0039 16.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 CEG42687.1 - 0.018 14.6 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CEG42687.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase DUF2974 PF11187.8 CEG42687.1 - 0.15 11.6 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WW PF00397.26 CEG42688.1 - 0.00032 20.7 1.5 0.0007 19.6 1.5 1.6 1 0 0 1 1 1 1 WW domain FAIM1 PF06905.13 CEG42688.1 - 0.018 14.8 0.3 0.046 13.4 0.1 1.8 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) Mob1_phocein PF03637.17 CEG42689.1 - 6.4e-74 247.6 0.2 7.6e-74 247.3 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acetyltransf_1 PF00583.25 CEG42691.1 - 2.2e-12 47.3 0.0 2.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG42691.1 - 8e-10 38.7 0.0 1.8e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG42691.1 - 5.4e-09 36.4 0.0 7.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEG42691.1 - 0.00041 20.4 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEG42691.1 - 0.0015 19.2 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CEG42691.1 - 0.0047 16.6 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CEG42691.1 - 0.0095 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 CEG42691.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 CEG42691.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 CEG42691.1 - 0.082 12.4 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Pkinase_Tyr PF07714.17 CEG42692.1 - 1.9e-46 158.5 0.0 3.5e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG42692.1 - 1.1e-45 156.1 0.0 1.6e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CEG42692.1 - 0.006 15.6 0.3 0.1 11.5 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain cNMP_binding PF00027.29 CEG42693.1 - 2.7e-26 91.4 2.8 2.8e-10 40.1 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Filo_VP24 PF06389.11 CEG42693.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 eIF2A PF08662.11 CEG42694.1 - 3.5e-53 180.4 4.8 4e-49 167.1 1.7 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CEG42694.1 - 1.2e-10 41.1 0.2 2.9e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 CEG42694.1 - 1.7e-06 28.2 0.3 6.7 7.1 0.0 6.1 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEG42694.1 - 4.5e-05 21.7 0.2 0.00023 19.4 0.1 2.0 1 1 0 2 2 2 1 IKI3 family WD40 PF00400.32 CEG42694.1 - 0.047 14.6 1.3 68 4.6 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Put_Phosphatase PF06888.12 CEG42695.1 - 0.03 13.7 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative Phosphatase PSI_PsaF PF02507.15 CEG42698.1 - 0.076 12.9 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III UCH PF00443.29 CEG42700.1 - 2.2e-42 145.4 0.1 3.3e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG42700.1 - 2.4e-06 27.4 0.1 1.9e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mt_ATP-synt_D PF05873.12 CEG42702.1 - 0.065 13.1 0.6 0.14 12.0 0.6 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) COesterase PF00135.28 CEG42702.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.0 1 0 0 1 1 1 0 Carboxylesterase family Jacalin PF01419.17 CEG42704.1 - 4.3e-08 33.2 0.4 7.9e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain CytochromB561_N PF09786.9 CEG42706.1 - 1.8e-21 76.8 0.1 2.6e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal RNA_pol_Rpc34 PF05158.12 CEG42708.1 - 2.4e-71 240.9 0.9 5.3e-50 170.7 0.2 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CEG42708.1 - 3.4e-05 23.9 0.5 0.00015 21.9 0.5 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.19 CEG42708.1 - 0.00023 21.0 0.2 0.085 12.8 0.0 2.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 CEG42708.1 - 0.0016 18.3 0.1 0.0027 17.6 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 CEG42708.1 - 0.0097 16.4 0.3 0.045 14.2 0.2 2.2 3 0 0 3 3 3 1 Winged helix DNA-binding domain Chlorosome_CsmC PF11098.8 CEG42708.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Rrf2 PF02082.20 CEG42708.1 - 0.079 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator DUF2250 PF10007.9 CEG42708.1 - 0.09 12.9 0.3 0.92 9.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RPA_C PF08784.11 CEG42708.1 - 0.12 13.0 0.1 0.62 10.7 0.0 2.2 2 1 0 2 2 2 0 Replication protein A C terminal Snapin_Pallidin PF14712.6 CEG42708.1 - 0.14 12.6 1.0 0.3 11.5 1.0 1.5 1 0 0 1 1 1 0 Snapin/Pallidin WD40 PF00400.32 CEG42709.1 - 2.4e-39 132.6 14.1 6.7e-08 33.1 0.2 12.0 13 0 0 13 13 12 7 WD domain, G-beta repeat Utp12 PF04003.12 CEG42709.1 - 1.6e-21 76.6 1.4 2.7e-21 75.9 1.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CEG42709.1 - 3.5e-21 75.3 0.0 0.0054 17.0 0.0 7.9 2 2 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG42709.1 - 3.2e-06 26.3 0.1 0.46 9.4 0.0 4.3 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEG42709.1 - 8.4e-06 25.8 0.2 3 7.7 0.0 4.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEG42709.1 - 0.00012 20.9 0.7 1.1 7.9 0.0 3.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CEG42709.1 - 0.00015 20.5 0.0 0.49 8.9 0.0 3.2 3 0 0 3 3 3 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 CEG42709.1 - 0.0014 18.2 0.6 0.66 9.7 0.0 4.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature WD40_like PF17005.5 CEG42709.1 - 0.01 15.2 0.0 0.52 9.6 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain CDC45 PF02724.14 CEG42709.1 - 0.025 12.9 0.3 0.037 12.3 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PD40 PF07676.12 CEG42709.1 - 0.035 14.1 0.0 32 4.6 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 CEG42710.1 - 3.6e-49 163.7 9.9 1.2e-07 32.3 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG42710.1 - 2.3e-20 72.7 0.0 1.1e-05 25.6 0.0 6.0 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG42710.1 - 1.4e-10 40.4 3.4 0.047 12.3 0.4 4.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG42710.1 - 4.1e-10 39.1 0.0 0.48 9.3 0.0 5.3 2 2 3 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEG42710.1 - 7.6e-07 29.2 0.0 5.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEG42710.1 - 0.0012 18.3 0.0 0.0072 15.7 0.0 2.0 1 1 1 2 2 2 1 WD40-like domain Frtz PF11768.8 CEG42710.1 - 0.0013 17.1 0.0 0.0086 14.4 0.0 2.2 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 CEG42710.1 - 0.093 13.2 0.0 21 5.7 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Nucleoporin_N PF08801.11 CEG42710.1 - 0.11 11.3 0.1 20 3.8 0.0 3.7 3 2 1 4 4 4 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 CEG42710.1 - 0.13 10.8 0.0 0.3 9.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain TPR_1 PF00515.28 CEG42711.1 - 1.7e-22 78.2 0.0 1.8e-07 30.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG42711.1 - 5.7e-18 63.5 0.0 6.1e-06 25.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG42711.1 - 1.1e-15 57.1 0.1 3.5e-06 26.6 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CEG42711.1 - 9.3e-12 44.2 0.1 0.00035 20.5 0.2 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42711.1 - 4.8e-08 33.2 0.7 7.3e-05 23.0 0.8 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG42711.1 - 9.6e-08 32.2 0.1 0.0044 17.7 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG42711.1 - 1.5e-06 28.2 0.2 0.014 15.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG42711.1 - 6.7e-06 26.7 0.0 0.057 14.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG42711.1 - 4.3e-05 23.6 2.6 0.068 13.6 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG42711.1 - 5.6e-05 22.9 1.0 2.7 8.2 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG42711.1 - 5.6e-05 23.6 0.5 0.0026 18.2 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG42711.1 - 0.00023 21.6 0.3 0.0091 16.6 0.4 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat KIND PF16474.5 CEG42711.1 - 0.00089 19.2 0.5 0.0018 18.2 0.5 1.5 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain BTAD PF03704.17 CEG42711.1 - 0.0083 16.6 1.1 0.032 14.6 1.0 1.9 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 CEG42711.1 - 0.015 14.5 0.1 1.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat OSCP PF00213.18 CEG42711.1 - 0.064 13.4 1.5 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit IQ PF00612.27 CEG42712.1 - 1.8e-05 24.1 1.0 3.6e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Baculo_PEP_C PF04513.12 CEG42712.1 - 0.082 12.9 10.7 1.4 8.9 3.1 3.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rad17 PF03215.15 CEG42712.1 - 0.13 12.1 5.0 0.6 10.0 1.8 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain GlcNAc PF11397.8 CEG42712.1 - 0.38 10.2 4.1 4.2 6.7 0.0 2.7 2 1 1 3 3 3 0 Glycosyltransferase (GlcNAc) FUSC PF04632.12 CEG42712.1 - 6.2 5.2 16.6 0.6 8.6 10.1 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.32 CEG42713.1 - 3.7e-11 43.4 6.5 0.0023 18.7 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CTNNBL PF08216.11 CEG42714.1 - 1e-25 89.9 0.0 3.6e-25 88.2 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3877 PF12993.7 CEG42714.1 - 0.0057 16.5 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF1400 PF07176.11 CEG42714.1 - 0.016 15.5 0.7 4.3 7.6 0.5 2.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PP2C_C PF07830.13 CEG42714.1 - 0.054 14.0 2.2 0.07 13.6 0.6 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CTD_bind PF04818.13 CEG42714.1 - 0.067 14.0 0.2 1.1 10.2 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase II-binding domain. AAA_22 PF13401.6 CEG42714.1 - 0.21 11.9 1.6 0.96 9.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain baeRF_family12 PF18856.1 CEG42714.1 - 0.52 10.9 3.8 6 7.5 0.2 2.9 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Peptidase_S8 PF00082.22 CEG42715.1 - 1.8e-40 139.1 5.5 7.1e-40 137.1 5.5 1.9 1 1 0 1 1 1 1 Subtilase family Ubie_methyltran PF01209.18 CEG42716.1 - 2.4e-15 56.5 0.0 1.3e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CEG42716.1 - 2.3e-13 50.6 0.0 6.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG42716.1 - 1.4e-12 48.1 0.0 3.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG42716.1 - 6.6e-09 35.8 0.0 1.5e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG42716.1 - 7.5e-09 35.5 0.0 1.7e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG42716.1 - 5.2e-08 33.5 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG42716.1 - 4.2e-05 23.2 0.0 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain E2_bind PF08825.10 CEG42716.1 - 0.027 14.6 0.5 0.89 9.8 0.2 2.8 3 0 0 3 3 3 0 E2 binding domain AdoMet_MTase PF07757.13 CEG42716.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Glyco_hydro_7 PF00840.20 CEG42716.1 - 0.21 10.2 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 RRM_1 PF00076.22 CEG42718.1 - 4.4e-12 45.7 0.0 1.3e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S6 PF01250.17 CEG42718.1 - 2.6e-10 40.4 0.1 6.5e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S6 RNA_bind PF08675.11 CEG42718.1 - 0.019 15.0 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain RRM_7 PF16367.5 CEG42718.1 - 0.023 14.8 0.0 0.28 11.3 0.0 2.5 1 1 0 1 1 1 0 RNA recognition motif PPV_E1_C PF00519.17 CEG42718.1 - 0.064 12.1 0.1 0.092 11.6 0.1 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF4523 PF15023.6 CEG42718.1 - 0.08 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF2096 PF09869.9 CEG42718.1 - 0.08 13.0 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) DSS1_SEM1 PF05160.13 CEG42719.1 - 1e-16 60.7 16.5 1.5e-16 60.2 16.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 CEG42719.1 - 0.0048 16.8 4.6 0.0051 16.7 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) DUF4816 PF16086.5 CEG42719.1 - 0.84 9.6 5.6 1.4 8.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) AAA PF00004.29 CEG42720.1 - 3.8e-55 185.9 0.0 1.5e-42 145.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG42720.1 - 4.3e-12 46.7 1.3 0.00013 22.4 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CEG42720.1 - 2.1e-09 37.1 2.7 0.0013 18.5 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CEG42720.1 - 6.2e-09 35.8 0.0 7.6e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEG42720.1 - 2.7e-08 34.4 0.0 0.0077 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEG42720.1 - 3.8e-08 33.4 0.0 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CEG42720.1 - 9.7e-08 32.1 0.1 0.016 15.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CEG42720.1 - 1.7e-07 30.6 0.0 0.0037 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEG42720.1 - 1.9e-07 31.4 0.9 0.013 15.8 0.1 3.9 4 1 1 5 5 3 2 AAA domain AAA_14 PF13173.6 CEG42720.1 - 2.8e-07 30.6 0.0 0.002 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEG42720.1 - 8.9e-07 29.2 0.0 0.043 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CEG42720.1 - 1.1e-06 29.0 0.0 0.061 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CEG42720.1 - 1.2e-06 28.1 0.1 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 CEG42720.1 - 2.7e-06 27.3 0.0 0.072 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEG42720.1 - 2.7e-06 27.7 0.0 0.048 14.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 CEG42720.1 - 1e-05 25.1 0.0 0.085 12.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEG42720.1 - 1.2e-05 25.1 0.0 0.0022 17.7 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_3 PF07726.11 CEG42720.1 - 2.1e-05 24.4 0.0 0.33 10.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEG42720.1 - 2.9e-05 23.7 0.1 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 CEG42720.1 - 6.2e-05 23.0 0.0 0.064 13.2 0.0 2.5 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CEG42720.1 - 7.9e-05 22.6 0.6 0.62 10.0 0.0 2.8 3 0 0 3 3 2 2 NACHT domain Zeta_toxin PF06414.12 CEG42720.1 - 9e-05 21.8 0.0 0.088 12.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 CEG42720.1 - 0.00011 21.6 0.2 0.023 14.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CEG42720.1 - 0.00021 21.0 0.0 0.35 10.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 CEG42720.1 - 0.00025 21.0 0.0 0.00078 19.4 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain ATPase PF06745.13 CEG42720.1 - 0.00028 20.3 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_2 PF07724.14 CEG42720.1 - 0.00063 19.9 0.0 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 CEG42720.1 - 0.00087 19.3 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 CEG42720.1 - 0.0011 18.1 0.0 0.4 9.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 CEG42720.1 - 0.0013 19.2 0.0 1.9 9.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 CEG42720.1 - 0.0016 17.7 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.6 CEG42720.1 - 0.0027 18.1 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CEG42720.1 - 0.0028 17.6 0.0 0.73 9.7 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain Parvo_NS1 PF01057.17 CEG42720.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 CEG42720.1 - 0.0079 15.9 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 CEG42720.1 - 0.01 16.2 0.1 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CEG42720.1 - 0.016 14.4 0.0 7.8 5.6 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain dNK PF01712.19 CEG42720.1 - 0.02 14.8 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DAP3 PF10236.9 CEG42720.1 - 0.024 13.8 0.1 1.4 8.1 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.6 CEG42720.1 - 0.031 14.1 0.0 0.88 9.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEG42720.1 - 0.04 13.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase SKI PF01202.22 CEG42720.1 - 0.049 13.8 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.18 CEG42720.1 - 0.06 13.1 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 CEG42720.1 - 0.064 12.7 0.0 36 3.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein SRP54 PF00448.22 CEG42720.1 - 0.068 12.8 1.4 0.75 9.4 0.1 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.19 CEG42720.1 - 0.074 12.6 0.6 3.7 7.1 0.0 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 CEG42720.1 - 0.08 12.4 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CEG42720.1 - 0.081 12.1 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CEG42720.1 - 0.094 12.4 0.3 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CEG42720.1 - 0.12 12.0 0.0 21 4.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CEG42720.1 - 0.18 11.9 0.4 5.1 7.2 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF4911 PF16256.5 CEG42721.1 - 0.037 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) TPR_14 PF13428.6 CEG42721.1 - 0.049 14.5 0.1 0.56 11.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.16 CEG42721.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Inhibitor_I36 PF03995.13 CEG42721.1 - 0.066 13.2 4.7 0.34 10.9 0.1 3.3 3 0 0 3 3 3 0 Peptidase inhibitor family I36 TPR_2 PF07719.17 CEG42721.1 - 0.099 12.8 0.6 4.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat EXOSC1 PF10447.9 CEG42721.1 - 0.11 13.2 0.3 0.32 11.6 0.3 1.7 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF4219 PF13961.6 CEG42722.1 - 0.021 14.5 0.2 0.028 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) MbeD_MobD PF04899.12 CEG42723.1 - 0.0074 16.4 0.4 0.013 15.6 0.4 1.5 1 0 0 1 1 1 1 MbeD/MobD like Spc7 PF08317.11 CEG42723.1 - 0.0097 14.8 1.3 0.011 14.6 1.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.9 CEG42723.1 - 0.014 15.7 3.7 2.4 8.5 0.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.7 CEG42723.1 - 0.039 13.5 0.4 0.053 13.1 0.4 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Mer2 PF09074.10 CEG42723.1 - 0.04 13.7 1.3 0.051 13.4 0.2 1.6 2 0 0 2 2 2 0 Mer2 EzrA PF06160.12 CEG42723.1 - 0.042 12.0 2.6 0.077 11.2 2.6 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HAUS-augmin3 PF14932.6 CEG42723.1 - 0.044 13.4 2.3 0.19 11.3 2.6 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 CEG42723.1 - 0.049 13.7 2.7 0.32 11.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Erp_C PF06780.11 CEG42723.1 - 0.057 13.4 0.1 0.08 13.0 0.1 1.3 1 0 0 1 1 1 0 Erp protein C-terminus K-box PF01486.17 CEG42723.1 - 0.066 13.4 2.7 0.12 12.6 2.7 1.5 1 1 0 1 1 1 0 K-box region FlaC_arch PF05377.11 CEG42723.1 - 0.069 13.6 2.6 0.7 10.3 0.2 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 CEG42723.1 - 0.071 13.1 6.2 0.39 10.8 6.2 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 CEG42723.1 - 0.075 13.2 3.2 0.11 12.7 0.8 2.1 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II CCDC-167 PF15188.6 CEG42723.1 - 0.078 13.3 2.6 0.86 10.0 2.6 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prominin PF05478.11 CEG42723.1 - 0.079 10.9 0.9 0.092 10.7 0.9 1.0 1 0 0 1 1 1 0 Prominin Cob_adeno_trans PF01923.18 CEG42723.1 - 0.11 12.6 0.4 0.15 12.2 0.4 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase KfrA_N PF11740.8 CEG42723.1 - 0.13 13.0 1.2 0.16 12.6 1.2 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF2802 PF10975.8 CEG42723.1 - 0.24 11.5 3.0 1.8 8.8 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) bZIP_1 PF00170.21 CEG42724.1 - 1.5 9.0 13.2 3.3 7.9 13.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor TMEM156 PF15106.6 CEG42725.1 - 0.5 9.8 4.7 0.29 10.5 2.5 1.7 2 0 0 2 2 2 0 TMEM156 protein family DUF3674 PF12426.8 CEG42726.1 - 0.044 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF3657 PF12394.8 CEG42727.1 - 0.14 12.7 0.0 0.51 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein FAM135 TBCC_N PF16752.5 CEG42730.1 - 0.0049 17.3 1.7 0.0089 16.5 0.6 2.0 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain MIT PF04212.18 CEG42730.1 - 0.059 13.5 1.2 0.15 12.2 1.2 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain EF-G-binding_N PF07299.11 CEG42730.1 - 0.089 13.3 1.7 0.21 12.1 0.2 2.4 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF4398 PF14346.6 CEG42730.1 - 0.42 11.3 5.4 0.2 12.3 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) LRR_6 PF13516.6 CEG42731.1 - 4.6e-10 38.7 13.4 0.074 13.1 0.1 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 CEG42731.1 - 0.00022 21.3 8.5 4.3 8.3 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.7 CEG42731.1 - 0.015 15.7 17.1 0.63 10.5 5.2 3.9 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG42731.1 - 0.45 10.3 14.6 0.59 9.9 8.0 3.7 2 1 2 4 4 4 0 Leucine rich repeat CLPTM1 PF05602.12 CEG42732.1 - 4.1e-131 437.9 2.0 5.7e-131 437.5 2.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PDZ_6 PF17820.1 CEG42732.1 - 5.6e-12 45.3 0.2 0.013 15.4 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 CEG42732.1 - 2.8e-09 37.2 0.0 0.0016 18.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain PknG_rubred PF16919.5 CEG42732.1 - 0.029 14.5 0.0 0.029 14.5 0.0 3.0 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain PQ-loop PF04193.14 CEG42732.1 - 0.21 11.4 3.9 0.13 12.1 0.3 2.2 2 0 0 2 2 2 0 PQ loop repeat PIN_8 PF18476.1 CEG42732.1 - 1.5 8.6 7.8 0.054 13.3 1.5 1.7 2 0 0 2 2 2 0 PIN like domain MFS_2 PF13347.6 CEG42733.1 - 2.9e-10 39.3 9.0 2.9e-10 39.3 9.0 3.9 2 2 1 3 3 3 1 MFS/sugar transport protein DUF1656 PF07869.12 CEG42733.1 - 0.7 9.9 8.6 0.94 9.5 0.2 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1656) Methyltransf_16 PF10294.9 CEG42734.1 - 1.2e-27 96.8 0.0 1.8e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CEG42734.1 - 0.0012 18.7 0.1 0.0024 17.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 CEG42734.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 CEG42734.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FAM86 PF14904.6 CEG42734.1 - 0.0092 16.1 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function Methyltransf_25 PF13649.6 CEG42734.1 - 0.01 16.5 0.0 0.031 15.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CEG42734.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCMT PF01135.19 CEG42734.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CEG42734.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 CEG42734.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) EF1_GNE PF00736.19 CEG42735.1 - 4.9e-34 116.4 1.5 9.9e-34 115.4 1.5 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CEG42735.1 - 0.00086 19.7 12.7 0.00086 19.7 12.7 2.3 2 0 0 2 2 1 1 Eukaryotic elongation factor 1 beta central acidic region Pox_Ag35 PF03286.14 CEG42735.1 - 0.0015 18.4 13.2 0.0022 17.8 13.2 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CDC27 PF09507.10 CEG42735.1 - 0.0017 17.8 13.6 0.002 17.6 13.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Sororin PF09666.10 CEG42735.1 - 0.0069 16.6 0.8 0.0094 16.2 0.8 1.2 1 0 0 1 1 1 1 Sororin protein Pal1 PF08316.11 CEG42735.1 - 0.02 15.7 2.2 0.026 15.3 2.2 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Stm1_N PF09598.10 CEG42735.1 - 0.028 15.3 2.4 0.028 15.3 2.4 2.3 2 0 0 2 2 2 0 Stm1 UBA2_C PF16195.5 CEG42735.1 - 0.031 15.0 11.0 0.053 14.2 11.0 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Rrp15p PF07890.12 CEG42735.1 - 0.18 12.2 10.8 0.32 11.3 10.8 1.3 1 0 0 1 1 1 0 Rrp15p PBP1_TM PF14812.6 CEG42735.1 - 0.23 11.9 8.6 0.42 11.0 8.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ndc1_Nup PF09531.10 CEG42735.1 - 0.26 9.9 1.2 0.32 9.6 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3381 PF11861.8 CEG42735.1 - 0.4 10.5 12.9 0.61 9.9 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FAM176 PF14851.6 CEG42735.1 - 2.1 8.0 4.9 3.2 7.4 4.9 1.3 1 0 0 1 1 1 0 FAM176 family LRR_4 PF12799.7 CEG42737.1 - 1.3e-17 63.6 30.4 1.7e-05 25.1 4.0 4.9 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG42737.1 - 9.2e-16 57.4 26.2 1.6e-05 24.6 2.4 4.5 3 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CEG42737.1 - 7.8e-14 51.5 8.6 5.9e-11 42.2 1.9 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CEG42737.1 - 0.00019 21.2 20.7 0.43 10.8 0.3 6.6 7 0 0 7 7 7 3 Leucine Rich repeat PIP5K PF01504.18 CEG42738.1 - 7.1e-63 212.4 0.0 1.3e-62 211.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG42738.1 - 0.00022 20.6 4.8 0.00022 20.6 4.8 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Prefoldin PF02996.17 CEG42739.1 - 1e-26 93.2 2.9 1e-26 93.2 2.9 1.4 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 CEG42739.1 - 0.0036 17.2 7.3 0.0045 16.9 2.0 2.3 1 1 2 3 3 3 1 Prefoldin subunit NBP1 PF08537.10 CEG42739.1 - 0.0045 16.4 0.6 0.0065 15.9 0.6 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 CdvA PF18822.1 CEG42739.1 - 0.079 12.8 6.4 0.55 10.1 6.4 2.0 1 1 0 1 1 1 0 CdvA-like coiled-coil domain DUF2353 PF09789.9 CEG42739.1 - 0.29 10.5 9.1 0.84 8.9 1.2 1.9 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Fib_alpha PF08702.10 CEG42739.1 - 0.37 11.0 4.2 5.7 7.1 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PIH1_CS PF18201.1 CEG42742.1 - 1.3e-11 44.8 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain DSPc PF00782.20 CEG42743.1 - 1.1e-25 90.0 0.3 2.5e-25 88.8 0.3 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 CEG42743.1 - 3.6e-05 23.6 1.6 0.00023 21.0 0.2 2.4 2 0 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.27 CEG42743.1 - 0.00044 19.9 0.3 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CEG42743.1 - 0.0027 17.4 0.2 0.0079 15.9 0.2 1.7 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPn PF14671.6 CEG42743.1 - 0.16 12.4 0.8 0.33 11.4 0.2 1.8 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half BRCT PF00533.26 CEG42745.1 - 5.4e-14 52.3 0.1 2.4e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-RING_6 PF14835.6 CEG42745.1 - 7.8e-07 28.9 4.1 2e-06 27.5 4.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CEG42745.1 - 2.6e-06 27.2 19.0 5e-06 26.3 19.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG42745.1 - 4.3e-06 26.5 17.8 7.8e-06 25.6 17.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 CEG42745.1 - 1.6e-05 25.2 0.0 0.00073 19.9 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CEG42745.1 - 0.00021 21.3 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C3HC4_4 PF15227.6 CEG42745.1 - 0.00024 21.2 15.7 0.00057 20.0 15.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CEG42745.1 - 0.001 19.3 16.2 0.0021 18.4 16.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG42745.1 - 0.0015 18.4 13.7 0.0025 17.6 13.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RTT107_BRCT_5 PF16770.5 CEG42745.1 - 0.0039 17.0 0.0 0.017 15.0 0.0 2.2 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PolC_DP2 PF03833.13 CEG42745.1 - 0.013 13.4 2.4 0.025 12.5 2.4 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_UBOX PF13445.6 CEG42745.1 - 0.075 13.1 17.4 0.17 11.9 17.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 CEG42745.1 - 0.69 10.2 14.6 2.5 8.5 14.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG42745.1 - 1.1 9.3 16.3 2.3 8.2 16.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CEG42745.1 - 5.4 6.9 11.8 12 5.7 11.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MinE PF03776.14 CEG42746.1 - 6.4e-15 54.9 0.1 8e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE V-ATPase_C PF03223.15 CEG42747.1 - 0.023 14.1 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Methyltransf_16 PF10294.9 CEG42754.1 - 3e-18 66.1 0.1 4.6e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG42754.1 - 6.5e-10 38.9 0.0 7.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 CEG42754.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CEG42754.1 - 0.00038 21.1 0.7 0.0021 18.6 0.1 2.4 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 CEG42754.1 - 0.00097 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CEG42754.1 - 0.0021 17.9 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CEG42754.1 - 0.0026 18.5 0.8 0.011 16.5 0.1 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG42754.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEG42754.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.16 CEG42754.1 - 0.081 12.1 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.12 CEG42754.1 - 0.086 13.6 0.3 0.31 11.8 0.3 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEG42754.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.23 CEG42755.1 - 8.4e-16 58.1 0.0 1.4e-13 50.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG42755.1 - 2.5e-08 33.6 0.1 6.3e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG42755.1 - 4.5e-07 29.9 0.0 6.4e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CEG42755.1 - 7.7e-05 22.8 0.0 0.00033 20.8 0.0 2.1 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 CEG42755.1 - 0.0092 15.5 0.5 1.7 8.1 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG42755.1 - 0.035 14.5 1.2 8.3 6.8 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain VPR PF00522.18 CEG42755.1 - 0.23 11.5 1.6 0.65 10.1 1.6 1.7 1 0 0 1 1 1 0 VPR/VPX protein ABC_tran PF00005.27 CEG42755.1 - 9.6 6.7 6.6 3.3 8.2 0.2 3.1 4 0 0 4 4 4 0 ABC transporter ANAPC4_WD40 PF12894.7 CEG42756.1 - 2.6e-14 53.3 0.0 0.043 14.1 0.0 7.1 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CEG42756.1 - 1.2e-10 41.5 26.7 0.064 13.1 0.0 10.6 5 3 6 11 11 11 4 Region in Clathrin and VPS WD40 PF00400.32 CEG42756.1 - 4.9e-08 33.5 2.3 9.8 7.2 0.0 6.5 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CEG42756.1 - 6e-07 28.9 14.8 0.001 18.2 0.7 4.8 2 2 2 4 4 4 2 Coatomer WD associated region PPR PF01535.20 CEG42756.1 - 0.045 14.0 12.1 20 5.7 0.0 8.1 10 1 1 11 11 8 0 PPR repeat Mistic PF11458.8 CEG42756.1 - 0.057 13.4 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 Membrane-integrating protein Mistic TPR_4 PF07721.14 CEG42756.1 - 0.058 14.0 5.7 5.3 8.0 0.3 5.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Sec16_C PF12931.7 CEG42756.1 - 0.059 13.0 2.8 1.6 8.3 1.0 4.1 3 1 0 3 3 3 0 Sec23-binding domain of Sec16 TPR_7 PF13176.6 CEG42756.1 - 0.06 13.4 23.8 7.6 6.8 0.6 10.2 9 2 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG42756.1 - 0.46 10.4 29.4 3.9 7.5 0.3 9.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG42756.1 - 0.63 9.8 3.3 12 5.6 0.0 5.0 4 0 0 4 4 4 0 TPR repeat DUF410 PF04190.13 CEG42756.1 - 1.1 9.0 18.3 0.083 12.7 1.7 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF410) TPR_2 PF07719.17 CEG42756.1 - 1.3 9.3 43.4 0.069 13.3 0.7 11.4 14 1 1 15 15 13 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42756.1 - 2.5 8.4 33.2 9.8 6.5 0.3 9.1 9 2 1 10 10 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG42756.1 - 3.3 8.1 17.2 93 3.6 0.1 8.8 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG42756.1 - 5.7 8.0 41.7 9.4 7.4 0.1 11.9 7 3 4 12 12 11 0 Tetratricopeptide repeat RVT_3 PF13456.6 CEG42757.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Ribonucleas_3_3 PF14622.6 CEG42758.1 - 1.8e-21 76.6 0.0 3.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CEG42758.1 - 1.2e-16 61.2 0.0 2.9e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 CEG42758.1 - 7.9e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif SDA1 PF05285.12 CEG42759.1 - 1.1 8.7 31.1 1.2 8.5 31.1 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 CEG42759.1 - 2.5 6.6 28.5 2.7 6.5 28.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.9 CEG42759.1 - 2.7 7.0 25.7 2.9 6.9 25.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CEG42759.1 - 7 4.7 27.4 7.4 4.6 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CEG42759.1 - 8 5.7 30.1 9.1 5.5 30.1 1.2 1 0 0 1 1 1 0 BUD22 Carboxyl_trans PF01039.22 CEG42760.1 - 1.8e-151 505.1 0.0 2.4e-151 504.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Spt5-NGN PF03439.13 CEG42760.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Trypsin_2 PF13365.6 CEG42761.1 - 0.0028 18.5 0.0 0.0077 17.1 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG42761.1 - 0.026 14.3 0.2 1 9.2 0.1 2.2 2 0 0 2 2 2 0 Trypsin EGF PF00008.27 CEG42762.1 - 0.01 16.1 7.1 0.01 16.1 7.1 5.0 4 0 0 4 4 4 0 EGF-like domain EGF_2 PF07974.13 CEG42762.1 - 0.011 16.1 9.2 0.011 16.1 9.2 5.0 5 0 0 5 5 5 0 EGF-like domain Lipase_3 PF01764.25 CEG42765.1 - 3.6e-06 26.9 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEG42765.1 - 0.0022 18.6 0.1 0.0051 17.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CEG42765.1 - 0.0084 15.8 0.4 0.018 14.8 0.1 1.6 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 CEG42765.1 - 0.015 14.6 0.2 0.081 12.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG42765.1 - 0.15 11.7 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CEG42765.1 - 0.18 11.3 0.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ZZ PF00569.17 CEG42766.1 - 2.3e-08 33.7 11.9 2.3e-08 33.7 11.9 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-RING_2 PF13639.6 CEG42766.1 - 2.5e-07 30.9 32.2 3.2e-05 24.2 6.6 4.0 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 CEG42766.1 - 4.1e-06 26.7 9.7 0.0014 18.6 0.4 3.1 2 0 0 2 2 2 2 RING-type zinc-finger PHD PF00628.29 CEG42766.1 - 4.6e-05 23.2 6.1 4.6e-05 23.2 6.1 3.9 3 1 0 3 3 3 1 PHD-finger zf-C3HC4_2 PF13923.6 CEG42766.1 - 0.00035 20.3 0.2 0.00035 20.3 0.2 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG42766.1 - 0.0018 17.9 14.2 0.011 15.4 0.5 3.4 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_5 PF14634.6 CEG42766.1 - 0.017 15.1 0.7 0.017 15.1 0.7 4.2 3 0 0 3 3 3 0 zinc-RING finger domain zf-rbx1 PF12678.7 CEG42766.1 - 0.041 14.2 0.6 0.041 14.2 0.6 3.9 3 1 0 3 3 3 0 RING-H2 zinc finger domain TORC_M PF12885.7 CEG42766.1 - 0.093 12.7 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain zf-C3HC4 PF00097.25 CEG42766.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DER1 PF04511.15 CEG42767.1 - 8.5e-60 202.0 13.1 1e-59 201.7 13.1 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 CEG42767.1 - 0.067 12.9 2.3 0.069 12.9 0.3 1.9 1 1 1 2 2 2 0 Oleosin Glutaredoxin PF00462.24 CEG42770.1 - 5.5e-21 74.5 0.0 1.4e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin zf-CCCH PF00642.24 CEG42770.1 - 3.3e-09 36.4 2.7 3.3e-09 36.4 2.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG42770.1 - 1.4e-05 25.0 4.5 4.2e-05 23.4 4.5 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 CEG42770.1 - 2.2e-05 24.2 10.3 2.2e-05 24.2 10.3 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG42770.1 - 6.8e-05 23.1 11.9 6.8e-05 23.1 11.9 3.2 4 0 0 4 4 3 1 Ring finger domain zf-CCCH_4 PF18044.1 CEG42770.1 - 0.00046 19.9 2.8 0.00046 19.9 2.8 2.2 2 0 0 2 2 1 1 CCCH-type zinc finger zf-C3HC4_2 PF13923.6 CEG42770.1 - 0.00049 19.9 11.2 0.00049 19.9 11.2 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF836 PF05768.14 CEG42770.1 - 0.0011 19.3 0.1 0.003 17.9 0.1 1.9 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-RING_UBOX PF13445.6 CEG42770.1 - 0.0013 18.7 11.6 0.0042 17.1 11.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG42770.1 - 0.0015 18.4 15.1 0.0015 18.4 15.1 3.3 4 0 0 4 4 4 1 zinc-RING finger domain GST_N_3 PF13417.6 CEG42770.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C3HC4 PF00097.25 CEG42770.1 - 0.025 14.4 12.9 0.025 14.4 12.9 3.2 4 0 0 4 4 3 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin_2 PF13098.6 CEG42770.1 - 0.21 12.0 2.7 0.53 10.7 0.1 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain zf-RING_10 PF16685.5 CEG42770.1 - 0.25 11.5 10.4 1.2 9.3 10.4 2.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Thioredoxin_3 PF13192.6 CEG42770.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.7 3 1 0 3 3 3 0 Thioredoxin domain PSII_Pbs31 PF18240.1 CEG42770.1 - 0.43 11.0 3.1 0.93 10.0 0.0 2.7 2 1 1 3 3 3 0 Photosystem II Psb31 protein zf-P11 PF03854.14 CEG42770.1 - 1.2 8.9 6.9 5 6.9 6.9 2.1 1 0 0 1 1 1 0 P-11 zinc finger Leu_zip PF15294.6 CEG42776.1 - 2.7e-23 82.9 30.1 2.4e-17 63.3 5.8 2.3 1 1 1 2 2 2 2 Leucine zipper ABC_tran_CTD PF16326.5 CEG42776.1 - 0.035 14.4 3.3 0.035 14.4 3.3 3.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain NYD-SP28 PF14772.6 CEG42776.1 - 0.053 13.6 22.7 0.8 9.8 0.3 3.5 2 2 1 3 3 3 0 Sperm tail DUF948 PF06103.11 CEG42776.1 - 0.26 11.6 2.9 1.1 9.6 2.9 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Not3 PF04065.15 CEG42776.1 - 0.33 10.3 22.7 1.8 8.0 0.8 2.6 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component XPC-binding PF09280.11 CEG42776.1 - 0.48 10.2 3.9 0.14 11.9 0.5 1.9 2 0 0 2 2 2 0 XPC-binding domain Prominin PF05478.11 CEG42776.1 - 0.91 7.4 15.5 2.1 6.2 15.4 1.7 1 1 0 1 1 1 0 Prominin Phage_GPO PF05929.11 CEG42776.1 - 2.8 7.5 14.6 0.16 11.5 8.8 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5301 PF17225.3 CEG42776.1 - 3.1 8.3 6.8 2.5 8.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5300) Occludin_ELL PF07303.13 CEG42776.1 - 6.6 7.5 18.9 4.2 8.1 12.5 2.9 2 1 0 2 2 2 0 Occludin homology domain DUF4239 PF14023.6 CEG42776.1 - 9.8 5.8 8.3 6 6.5 4.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) PIP5K PF01504.18 CEG42777.1 - 6.5e-67 225.6 0.2 6.5e-67 225.6 0.2 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Yip1 PF04893.17 CEG42777.1 - 0.066 12.9 6.2 0.053 13.2 1.2 2.3 2 0 0 2 2 2 0 Yip1 domain 7tm_2 PF00002.24 CEG42777.1 - 0.19 11.0 11.5 0.019 14.3 6.4 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) DUF373 PF04123.13 CEG42777.1 - 7.8 5.8 8.2 0.26 10.7 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Forkhead_N PF08430.12 CEG42780.1 - 0.063 13.9 0.1 0.078 13.6 0.1 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region V-SNARE_C PF12352.8 CEG42781.1 - 8e-17 61.3 7.0 1.1e-16 60.8 5.2 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CEG42781.1 - 8.7e-08 32.0 3.1 8.8e-08 32.0 0.4 2.2 3 0 0 3 3 3 1 Sec20 Dict-STAT-coil PF09267.10 CEG42781.1 - 0.25 11.7 2.3 5 7.5 0.0 2.8 2 1 1 3 3 3 0 Dictyostelium STAT, coiled coil Pkinase PF00069.25 CEG42782.1 - 1e-47 162.7 0.1 1e-47 162.7 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42782.1 - 2e-22 79.7 0.0 5.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG42782.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CBM_2 PF00553.19 CEG42783.1 - 0.035 14.4 0.1 0.038 14.3 0.1 1.1 1 0 0 1 1 1 0 Cellulose binding domain DUF1231 PF06802.11 CEG42786.1 - 0.047 12.8 0.1 0.052 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) MFS_1 PF07690.16 CEG42787.1 - 6.5e-32 110.8 24.7 7.5e-22 77.7 10.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG42787.1 - 0.1 11.4 21.8 0.0088 14.9 5.6 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter MFS_1_like PF12832.7 CEG42787.1 - 0.12 11.2 19.9 0.29 10.0 0.4 3.4 3 1 0 3 3 3 0 MFS_1 like family YrhC PF14143.6 CEG42787.1 - 4.1 7.6 6.9 5.6 7.1 0.0 3.9 4 0 0 4 4 4 0 YrhC-like protein Pkinase PF00069.25 CEG42788.1 - 3.2e-61 207.0 0.0 4.4e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42788.1 - 1e-40 139.7 0.0 1.8e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG42788.1 - 4.4e-06 25.7 0.0 1.7e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEG42788.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Fez1 PF06818.15 CEG42788.1 - 0.00082 19.9 0.8 0.0015 19.0 0.8 1.4 1 0 0 1 1 1 1 Fez1 Rabaptin PF03528.15 CEG42788.1 - 0.0042 15.9 3.6 0.0062 15.3 3.6 1.1 1 0 0 1 1 1 1 Rabaptin APH PF01636.23 CEG42788.1 - 0.053 13.4 2.5 0.52 10.2 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3552 PF12072.8 CEG42788.1 - 0.27 10.6 5.6 0.49 9.8 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) LMSTEN PF07988.12 CEG42788.1 - 0.87 9.1 4.2 8.1 6.0 4.4 2.4 2 0 0 2 2 2 0 LMSTEN motif zf-C3HC4_3 PF13920.6 CEG42789.1 - 8.5e-16 57.6 11.8 1.5e-15 56.7 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG42789.1 - 3.9e-08 33.0 11.6 7.5e-08 32.1 11.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CEG42789.1 - 1.1e-06 28.9 13.7 2.6e-06 27.6 13.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEG42789.1 - 0.0035 17.3 11.3 0.0085 16.0 11.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEG42789.1 - 0.067 13.1 13.2 0.17 11.8 13.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CEG42789.1 - 0.94 9.2 14.1 0.21 11.3 7.5 2.6 2 1 0 2 2 2 0 P-11 zinc finger zf-RING_10 PF16685.5 CEG42789.1 - 4 7.6 12.2 1.6 9.0 8.6 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 H2O2_YaaD PF03883.14 CEG42790.1 - 5.9e-61 206.0 0.7 7e-60 202.4 0.2 2.0 1 1 1 2 2 2 2 Peroxide stress protein YaaA SKN1 PF03935.15 CEG42791.1 - 1.3e-56 192.0 24.5 9.5e-26 90.3 2.6 5.7 5 2 0 5 5 5 3 Beta-glucan synthesis-associated protein (SKN1) PsbN PF02468.15 CEG42791.1 - 0.048 13.5 1.2 0.11 12.4 1.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) EB PF01683.18 CEG42791.1 - 2.1 8.7 9.9 0.096 13.0 1.9 2.9 3 0 0 3 3 3 0 EB module BT1 PF03092.16 CEG42793.1 - 0.0005 18.4 4.5 0.0005 18.4 4.5 2.5 2 1 0 2 2 2 2 BT1 family Gate PF07670.14 CEG42793.1 - 0.056 13.7 3.3 0.49 10.7 0.0 3.3 2 2 0 3 3 3 0 Nucleoside recognition Adeno_52K PF03052.15 CEG42793.1 - 0.23 10.9 0.1 0.36 10.2 0.1 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa DUF3490 PF11995.8 CEG42793.1 - 0.35 10.7 0.7 0.64 9.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) MLTD_N PF06474.12 CEG42793.1 - 5.1 7.3 5.1 1 9.6 0.8 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif SKN1 PF03935.15 CEG42794.1 - 3.4e-50 170.9 16.3 5e-32 111.0 5.4 4.4 3 2 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 CEG42794.1 - 0.54 10.6 3.0 0.94 9.9 0.7 2.5 2 0 0 2 2 2 0 Late nodulin protein adh_short PF00106.25 CEG42798.1 - 1.1e-30 106.5 0.6 4e-30 104.7 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG42798.1 - 2.8e-24 86.0 0.5 5.4e-24 85.0 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CEG42798.1 - 8.4e-06 25.4 0.0 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ntox5 PF15543.6 CEG42798.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 5 NAD_binding_10 PF13460.6 CEG42798.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 CEG42798.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain SSF PF00474.17 CEG42800.1 - 8.4e-06 24.9 35.4 0.00015 20.7 25.4 3.0 2 1 0 2 2 2 2 Sodium:solute symporter family DUF5422 PF17459.2 CEG42800.1 - 0.015 15.5 3.1 0.015 15.5 3.1 3.4 2 1 0 4 4 4 0 Family of unknown function (DUF5422) Tub PF01167.18 CEG42801.1 - 7.6e-52 176.5 0.0 2.1e-51 175.0 0.0 1.7 1 1 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 CEG42801.1 - 3.3e-09 36.9 11.2 3.3e-09 36.9 11.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG42801.1 - 2.4e-08 33.7 10.1 2.4e-08 33.7 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG42801.1 - 2.5e-07 30.5 14.8 5.9e-07 29.2 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG42801.1 - 7.9e-06 25.6 11.1 7.9e-06 25.6 11.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG42801.1 - 0.0001 22.3 9.5 0.00026 20.9 6.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CEG42801.1 - 0.00041 20.6 9.2 0.00041 20.6 9.2 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEG42801.1 - 0.00088 19.1 13.1 0.001 18.9 8.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 CEG42801.1 - 0.013 15.8 0.3 0.013 15.8 0.3 3.4 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 CEG42801.1 - 0.026 14.5 1.0 0.026 14.5 1.0 1.9 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CEG42801.1 - 0.061 13.2 5.6 0.14 12.0 5.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CEG42801.1 - 0.069 13.1 15.7 0.024 14.6 11.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEG42801.1 - 0.2 11.7 6.0 0.046 13.8 2.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 CEG42801.1 - 0.36 11.0 14.8 2 8.6 14.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 CEG42801.1 - 0.45 10.7 13.9 0.42 10.8 10.7 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_4 PF13717.6 CEG42801.1 - 1.9 8.5 7.2 11 6.0 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEG42801.1 - 8.3 6.5 13.3 10 6.2 7.5 2.4 2 0 0 2 2 2 0 zinc-ribbons Suc_Fer-like PF06999.12 CEG42802.1 - 1.3e-27 97.0 0.0 1.6e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like AF0941-like PF14591.6 CEG42803.1 - 0.012 16.2 0.0 0.015 15.9 0.0 1.1 1 0 0 1 1 1 0 AF0941-like Uma2 PF05685.12 CEG42804.1 - 9.7e-08 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease PhnI PF05861.12 CEG42804.1 - 0.037 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Botulinum_HA-17 PF05588.11 CEG42805.1 - 0.041 14.0 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain ptaRNA1_toxin PF12703.7 CEG42805.1 - 0.11 12.6 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system GWT1 PF06423.12 CEG42805.1 - 0.3 11.2 4.6 0.17 12.0 1.9 1.8 2 0 0 2 2 2 0 GWT1 Pkinase PF00069.25 CEG42807.1 - 1.9e-72 243.8 0.0 2.3e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42807.1 - 6.1e-39 133.8 0.0 7.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42807.1 - 4.5e-06 26.2 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG42807.1 - 0.12 11.2 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEG42807.1 - 0.15 11.7 0.0 8 6.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 CEG42808.1 - 6.6e-07 29.9 10.5 0.096 13.6 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG42808.1 - 8e-05 22.9 0.0 14 6.1 0.0 5.0 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3427 PF11907.8 CEG42810.1 - 0.0042 16.4 0.0 0.0084 15.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3427) Gaa1 PF04114.14 CEG42811.1 - 4.9e-75 253.4 10.4 1.1e-73 249.0 10.4 2.2 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component IncF PF17626.2 CEG42811.1 - 0.95 9.9 3.9 1.4 9.3 1.6 2.5 2 0 0 2 2 2 0 Inclusion membrane protein F DUF3211 PF11485.8 CEG42813.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) HOOK PF05622.12 CEG42813.1 - 0.069 11.3 5.7 0.04 12.1 3.9 1.4 1 1 0 1 1 1 0 HOOK protein PA26 PF04636.13 CEG42813.1 - 0.47 9.3 2.4 17 4.2 0.0 2.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) WD40 PF00400.32 CEG42815.1 - 1.4e-13 51.1 0.0 4.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat CEP19 PF14933.6 CEG42815.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein ING PF12998.7 CEG42815.1 - 0.11 13.1 0.6 0.16 12.6 0.6 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF5305 PF17231.2 CEG42816.1 - 0.0091 15.4 0.3 0.015 14.7 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DAP10 PF07213.11 CEG42816.1 - 0.03 14.3 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein DUF4501 PF14946.6 CEG42816.1 - 0.041 14.0 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) UPF0239 PF06783.11 CEG42816.1 - 0.079 13.1 0.0 0.33 11.2 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) PP2C PF00481.21 CEG42817.1 - 2.6e-64 217.4 0.0 3.5e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 CEG42817.1 - 2.1e-17 63.2 0.0 4.7e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 FHA domain PP2C_2 PF13672.6 CEG42817.1 - 1.1e-07 31.7 0.0 3.9e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 CEG42817.1 - 9.2e-05 22.7 0.0 0.00029 21.1 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SpoIIE PF07228.12 CEG42817.1 - 0.0084 16.0 0.6 0.17 11.8 0.4 2.4 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Jagunal PF07086.12 CEG42818.1 - 0.047 13.8 0.4 0.068 13.2 0.4 1.2 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Tmemb_185A PF10269.9 CEG42818.1 - 0.051 13.3 1.0 0.086 12.5 1.0 1.3 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein TctB PF07331.11 CEG42818.1 - 0.066 13.5 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Voltage_CLC PF00654.20 CEG42818.1 - 0.17 11.1 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel LRR19-TM PF15176.6 CEG42818.1 - 0.79 9.7 3.9 0.41 10.7 0.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Spore_YhaL PF14147.6 CEG42818.1 - 1.2 8.8 6.9 5 6.9 0.4 2.6 2 0 0 2 2 2 0 Sporulation protein YhaL Uma2 PF05685.12 CEG42819.1 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Cass2 PF14526.6 CEG42820.1 - 1.6e-08 34.9 0.0 1.9e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein GyrI-like PF06445.15 CEG42820.1 - 6.9e-07 29.7 0.0 1.3e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 GyrI-like small molecule binding domain RXLR PF16810.5 CEG42821.1 - 0.0065 16.9 5.2 0.019 15.4 5.2 1.7 1 1 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity VID27_N PF17748.1 CEG42821.1 - 0.016 15.1 1.5 0.027 14.3 1.5 1.3 1 0 0 1 1 1 0 VID27 N-terminal region LapA_dom PF06305.11 CEG42822.1 - 0.071 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4083 PF13314.6 CEG42822.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MFS_1 PF07690.16 CEG42822.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily Ribosomal_L28 PF00830.19 CEG42823.1 - 6.2e-18 64.7 0.4 9e-18 64.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L28 family YHYH PF14240.6 CEG42824.1 - 0.0012 18.8 0.3 6.5 6.6 0.1 3.7 1 1 0 3 3 3 1 YHYH protein Lustrin_cystein PF14625.6 CEG42824.1 - 0.012 16.0 32.1 2.4 8.6 1.7 5.3 4 2 0 4 4 4 0 Lustrin, cysteine-rich repeated domain Defensin_int PF17858.1 CEG42824.1 - 0.023 14.7 12.5 7.3 6.7 0.3 4.5 4 0 0 4 4 4 0 Platypus intermediate defensin-like peptide DUF1177 PF06675.11 CEG42824.1 - 0.085 11.7 0.1 6 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1177) Torus PF16131.5 CEG42824.1 - 3.9 8.2 19.6 1.8 9.3 1.9 4.2 4 0 0 4 4 4 0 Torus domain DUF2441 PF10386.9 CEG42833.1 - 0.046 13.7 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) ComJ PF11033.8 CEG42834.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Competence protein J (ComJ) PPR PF01535.20 CEG42835.1 - 3.2e-17 61.5 10.9 0.027 14.7 0.0 14.1 17 0 0 17 17 17 2 PPR repeat PPR_2 PF13041.6 CEG42835.1 - 2e-15 56.7 11.0 0.39 11.0 0.0 12.2 10 2 5 15 15 15 5 PPR repeat family PPR_3 PF13812.6 CEG42835.1 - 2.8e-10 40.1 0.1 0.038 14.1 0.0 6.8 7 1 1 8 8 8 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEG42835.1 - 1.5e-07 31.0 6.1 0.9 9.3 0.0 7.8 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 CEG42835.1 - 3.4e-07 29.9 3.2 0.041 13.2 0.2 5.4 5 1 1 6 6 6 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CEG42835.1 - 0.00023 21.6 14.0 0.76 10.3 0.1 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG42835.1 - 0.0016 18.3 0.2 5.1 7.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat CysG_dimeriser PF10414.9 CEG42835.1 - 0.025 14.3 0.1 0.56 10.0 0.0 3.2 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region HrpB1_HrpK PF09613.10 CEG42835.1 - 0.056 13.1 0.2 1.9 8.1 0.0 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_2 PF07719.17 CEG42835.1 - 0.15 12.2 2.6 2.1e+02 2.4 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat KCT2 PF17818.1 CEG42836.1 - 0.39 10.8 1.7 0.43 10.7 1.7 1.1 1 0 0 1 1 1 0 Keratinocyte-associated gene product Mito_carr PF00153.27 CEG42837.1 - 4e-57 190.1 2.4 1.5e-17 63.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Arm PF00514.23 CEG42838.1 - 0.0078 16.2 12.6 0.17 12.0 0.1 4.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG42838.1 - 0.041 14.4 0.3 0.27 11.8 0.0 2.5 2 0 0 2 2 2 0 HEAT-like repeat TF_Zn_Ribbon PF08271.12 CEG42838.1 - 0.11 12.0 0.3 0.23 11.0 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Cytochrom_B561 PF03188.16 CEG42839.1 - 5.3e-37 127.0 14.6 6.9e-37 126.6 12.9 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 CEG42839.1 - 0.08 13.1 14.1 0.047 13.8 4.9 2.7 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF2207 PF09972.9 CEG42839.1 - 7.4 5.2 5.9 2.6 6.7 3.3 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) 7TMR-HDED PF07697.11 CEG42840.1 - 0.017 15.2 0.1 0.017 15.2 0.1 3.2 3 0 0 3 3 3 0 7TM-HD extracellular HEAT_2 PF13646.6 CEG42840.1 - 0.13 12.7 5.6 1.4 9.4 0.3 4.2 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.22 CEG42840.1 - 1.3 9.5 3.3 1.1e+02 3.5 0.0 4.7 4 1 1 5 5 5 0 HEAT repeat SNARE PF05739.19 CEG42841.1 - 7.2e-08 32.3 1.2 1.9e-07 30.9 1.2 1.7 1 0 0 1 1 1 1 SNARE domain DUF3235 PF11574.8 CEG42841.1 - 0.018 15.9 0.3 0.037 14.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) DUF720 PF05302.11 CEG42841.1 - 0.099 12.5 2.9 0.18 11.6 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Tup_N PF08581.10 CEG42841.1 - 0.56 10.6 0.1 0.56 10.6 0.1 2.5 4 0 0 4 4 4 0 Tup N-terminal NTF2 PF02136.20 CEG42842.1 - 2.2e-22 79.8 0.0 3.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CEG42842.1 - 1.6e-14 53.4 0.0 2.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CEG42842.1 - 0.005 16.9 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain Pns11_12 PF17464.2 CEG42842.1 - 0.022 14.5 5.7 0.048 13.4 5.7 1.5 1 0 0 1 1 1 0 Non-structural protein 11 and 12 PROCN PF08083.11 CEG42843.1 - 9e-237 785.4 6.7 1.5e-236 784.7 6.7 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CEG42843.1 - 5.9e-128 425.3 0.2 1.1e-127 424.4 0.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 CEG42843.1 - 8.7e-88 292.0 4.5 2.9e-87 290.3 4.5 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CEG42843.1 - 1.2e-72 242.3 0.0 2.4e-72 241.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg PF10596.9 CEG42843.1 - 2.3e-64 216.2 0.8 7.5e-64 214.5 0.8 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PROCT PF08084.11 CEG42843.1 - 7.3e-55 184.2 0.2 1.8e-54 182.9 0.2 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CEG42843.1 - 1.4e-46 156.8 0.4 3.7e-46 155.4 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 TPR_2 PF07719.17 CEG42843.1 - 3.8e-12 45.3 19.0 0.011 15.8 0.0 9.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEG42843.1 - 5.6e-08 32.3 8.6 0.32 10.9 0.2 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG42843.1 - 7.8e-08 32.8 2.0 0.00078 20.0 0.0 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat JAB PF01398.21 CEG42843.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_8 PF13181.6 CEG42843.1 - 1.5e-05 24.8 9.2 0.058 13.6 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG42843.1 - 8.6e-05 22.3 1.1 0.076 13.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG42843.1 - 0.00064 19.9 19.4 3.4 8.0 0.0 6.5 5 1 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEG42843.1 - 0.0011 19.5 13.3 0.011 16.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG42843.1 - 0.0017 19.0 11.0 1.7 9.7 0.5 7.3 6 2 2 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG42843.1 - 0.0089 16.3 28.9 0.023 15.0 0.7 7.0 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG42843.1 - 0.012 15.5 3.2 0.074 13.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEG42843.1 - 1.9 8.6 7.1 0.31 11.1 0.4 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat YfdX PF10938.8 CEG42843.1 - 1.9 8.4 11.5 41 4.1 0.4 4.9 5 1 0 5 5 4 0 YfdX protein TPR_20 PF14561.6 CEG42843.1 - 2.5 8.5 5.1 2 8.8 1.7 2.7 4 0 0 4 4 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG42843.1 - 3.8 8.4 16.0 3.3 8.5 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Chibby PF14645.6 CEG42844.1 - 7.6e-06 26.3 2.5 1.4e-05 25.5 1.3 2.0 1 1 1 2 2 2 1 Chibby family Filament PF00038.21 CEG42844.1 - 0.0014 18.3 5.0 0.0017 18.0 5.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein DivIC PF04977.15 CEG42844.1 - 0.0022 17.7 6.5 0.023 14.5 0.8 2.2 2 0 0 2 2 2 1 Septum formation initiator bZIP_2 PF07716.15 CEG42844.1 - 0.0032 17.5 4.5 0.0032 17.5 4.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEG42844.1 - 0.0047 17.0 1.8 0.0047 17.0 1.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor Atg14 PF10186.9 CEG42844.1 - 0.013 14.6 4.4 0.015 14.4 4.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GIT_CC PF16559.5 CEG42844.1 - 0.028 14.3 3.5 0.078 12.9 3.5 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 CEG42844.1 - 0.029 14.7 4.0 0.029 14.7 4.0 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 CEG42844.1 - 0.031 14.4 8.8 0.052 13.7 8.6 1.4 1 1 0 1 1 1 0 Tropomyosin like DUF2312 PF10073.9 CEG42844.1 - 0.034 13.8 1.7 1.8 8.3 1.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TSC22 PF01166.18 CEG42844.1 - 0.037 14.4 0.9 0.074 13.4 0.9 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family PKcGMP_CC PF16808.5 CEG42844.1 - 0.039 13.8 0.2 0.081 12.8 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase STN1_2 PF09170.10 CEG42844.1 - 0.052 13.7 2.4 0.069 13.4 2.4 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4407 PF14362.6 CEG42844.1 - 0.061 12.7 6.0 0.087 12.2 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 CEG42844.1 - 0.072 13.1 2.4 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ADIP PF11559.8 CEG42844.1 - 0.078 13.1 11.9 0.24 11.5 9.8 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAM47 PF14642.6 CEG42844.1 - 0.15 11.6 1.1 0.19 11.2 1.1 1.1 1 0 0 1 1 1 0 FAM47 family YabA PF06156.13 CEG42844.1 - 0.2 12.3 4.6 0.28 11.8 4.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA zf-C4pol PF14260.6 CEG42844.1 - 0.21 12.1 4.7 0.089 13.3 2.1 1.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CENP-F_leu_zip PF10473.9 CEG42844.1 - 0.24 11.4 12.2 0.076 13.0 5.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sipho_Gp157 PF05565.11 CEG42844.1 - 0.25 11.3 6.5 0.068 13.2 2.7 1.8 1 1 1 2 2 2 0 Siphovirus Gp157 OmpH PF03938.14 CEG42844.1 - 1.1 9.6 7.7 1.7 9.0 7.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Histone_HNS PF00816.21 CEG42844.1 - 3.6 8.5 9.4 1.3 9.9 0.9 2.1 2 0 0 2 2 2 0 H-NS histone family GrpE PF01025.19 CEG42844.1 - 4 7.1 9.4 10 5.8 9.4 1.5 1 1 0 1 1 1 0 GrpE TMPIT PF07851.13 CEG42844.1 - 4.3 6.5 6.4 5.6 6.1 6.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein UxaE PF16257.5 CEG42845.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 tagaturonate epimerase Rtt106 PF08512.12 CEG42846.1 - 2e-25 89.0 0.0 4e-24 84.8 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CEG42846.1 - 6.6e-25 86.8 0.0 2.3e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CEG42846.1 - 1.1e-15 57.8 0.1 2.4e-14 53.5 0.0 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain zf-RING_2 PF13639.6 CEG42846.1 - 1.8e-10 41.0 1.6 3.2e-10 40.2 1.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG42846.1 - 1.2e-08 35.1 4.2 2.5e-08 34.1 3.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG42846.1 - 9.7e-08 31.7 1.7 2e-07 30.7 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG42846.1 - 3.8e-06 26.7 1.3 7.4e-06 25.7 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG42846.1 - 1.7e-05 24.4 3.9 4e-05 23.3 3.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEG42846.1 - 2.1e-05 24.3 3.8 3.5e-05 23.6 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG42846.1 - 3.1e-05 23.9 1.4 6.7e-05 22.8 1.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG42846.1 - 0.0011 18.7 1.3 0.0026 17.6 1.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CEG42846.1 - 0.0037 16.9 3.9 0.0075 15.9 3.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CEG42846.1 - 0.0047 16.9 1.2 0.0098 15.8 1.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEG42846.1 - 0.011 15.7 1.2 0.022 14.8 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PH_TFIIH PF08567.11 CEG42846.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Sensor PF13796.6 CEG42847.1 - 1.5 8.9 21.5 2.9 7.9 21.2 1.6 1 1 0 1 1 1 0 Putative sensor Pkinase PF00069.25 CEG42848.1 - 1.5e-74 250.7 0.0 1.1e-73 247.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42848.1 - 2e-51 174.8 0.0 1e-50 172.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42848.1 - 0.00012 21.6 0.0 0.00046 19.6 0.0 2.0 1 0 0 1 1 1 1 Kinase-like Arm PF00514.23 CEG42848.1 - 0.00049 20.0 5.5 3.8 7.7 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Kdo PF06293.14 CEG42848.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Histone_H2A_C PF16211.5 CEG42848.1 - 0.049 13.4 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 C-terminus of histone H2A V-ATPase_H_C PF11698.8 CEG42848.1 - 0.13 12.4 3.5 0.11 12.6 0.3 2.7 3 0 0 3 3 3 0 V-ATPase subunit H Gemin6 PF06372.12 CEG42849.1 - 0.00018 21.1 2.3 0.0012 18.5 0.1 3.2 3 0 0 3 3 3 1 Gemin6 protein RNA_pol_Rpb2_45 PF10385.9 CEG42849.1 - 0.076 13.3 0.1 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain DUF3232 PF11554.8 CEG42849.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3232) PX PF00787.24 CEG42851.1 - 3.6e-14 52.7 0.0 6.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 PX domain SHOCT PF09851.9 CEG42851.1 - 0.00075 19.2 0.2 0.0024 17.6 0.1 2.0 2 0 0 2 2 2 1 Short C-terminal domain zf-ribbon_3 PF13248.6 CEG42851.1 - 0.0025 17.1 2.7 0.0072 15.7 2.7 1.8 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 CEG42851.1 - 0.0028 17.6 0.5 0.0071 16.3 0.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon ADK_lid PF05191.14 CEG42851.1 - 0.066 13.2 1.8 0.14 12.2 1.8 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 CEG42851.1 - 0.17 11.4 2.4 0.33 10.5 2.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 CEG42851.1 - 0.19 11.2 1.0 0.42 10.1 0.4 1.8 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-RanBP PF00641.18 CEG42851.1 - 0.66 9.3 3.8 1.2 8.5 3.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-ACC PF17848.1 CEG42851.1 - 1.2 9.2 3.2 18 5.5 0.1 3.3 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain PX PF00787.24 CEG42852.1 - 2.7e-11 43.5 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 PX domain GAT PF03127.14 CEG42852.1 - 0.055 13.8 0.0 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 GAT domain MARVEL PF01284.23 CEG42855.1 - 0.018 15.1 3.4 0.02 14.9 3.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain HEAT PF02985.22 CEG42856.1 - 8e-07 28.8 6.7 1.2 9.5 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 CEG42856.1 - 3.6e-06 27.1 0.1 0.02 14.9 0.1 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEG42856.1 - 6.4e-06 26.5 0.8 0.23 11.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CEG42856.1 - 0.0021 18.5 1.0 5.2 7.7 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Nipped-B_C PF12830.7 CEG42856.1 - 0.018 15.0 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Ribosomal_L50 PF10501.9 CEG42856.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal subunit 39S CTK3 PF12243.8 CEG42856.1 - 0.099 12.6 0.8 1.1 9.3 0.0 2.9 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 MMS19_N PF14500.6 CEG42856.1 - 0.12 11.9 2.2 9.6 5.7 0.0 4.0 3 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 CEG42856.1 - 0.15 12.6 1.2 6 7.5 0.0 3.4 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Myosin_head PF00063.21 CEG42859.1 - 8.3e-220 731.5 0.1 1e-219 731.2 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 CEG42859.1 - 7.6e-33 113.0 8.8 9.3e-12 45.4 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 CEG42859.1 - 1.7e-28 97.8 8.2 0.004 17.5 0.1 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CEG42859.1 - 8.4e-26 87.2 2.5 0.014 15.9 0.0 9.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 CEG42859.1 - 3.9e-25 87.9 10.5 2.3e-07 31.2 0.1 7.6 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG42859.1 - 7.2e-23 80.4 9.5 1.3e-09 38.1 0.2 6.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) FYVE PF01363.21 CEG42859.1 - 7.5e-16 58.0 13.6 1.6e-15 57.0 13.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 CEG42859.1 - 0.0075 16.7 0.3 0.033 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG42859.1 - 0.065 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.23 CEG42860.1 - 5.7e-15 55.5 0.0 8.6e-15 54.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 CEG42861.1 - 8.5e-13 48.4 0.1 4.9e-12 45.9 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4632 PF15451.6 CEG42863.1 - 0.17 12.0 1.5 0.62 10.2 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase PF00069.25 CEG42864.1 - 9.1e-72 241.6 0.0 1.5e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42864.1 - 2.4e-36 125.3 0.0 4.4e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SRR1 PF07985.12 CEG42864.1 - 4.6e-14 52.2 0.0 1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 SRR1 Pkinase_fungal PF17667.1 CEG42864.1 - 0.0018 17.1 0.3 0.0055 15.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEG42864.1 - 0.0075 15.6 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CEG42864.1 - 0.021 14.4 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CEG42864.1 - 0.21 11.5 1.2 1.5 8.6 0.1 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 CEG42865.1 - 4.6e-13 48.7 16.5 5.6e-13 48.4 16.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4579 PF15158.6 CEG42865.1 - 0.063 13.0 0.2 0.063 13.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) EbsA PF17255.2 CEG42865.1 - 0.28 11.5 2.5 17 5.7 0.8 2.4 1 1 0 2 2 2 0 EbsA-like protein Asp-Al_Ex PF06826.12 CEG42865.1 - 3.2 7.5 13.9 1.1 9.0 9.7 1.8 1 1 1 2 2 2 0 Predicted Permease Membrane Region DUF5090 PF17009.5 CEG42865.1 - 3.3 7.6 8.3 2.3 8.1 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Na_H_Exchanger PF00999.21 CEG42866.1 - 3.4e-13 49.2 7.0 5.3e-13 48.5 7.0 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5401 PF17380.2 CEG42866.1 - 6.6 4.7 9.0 8.4 4.3 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2062 PF09835.9 CEG42871.1 - 4.1e-12 46.2 9.8 1.1e-11 44.8 9.8 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Zn_Tnp_IS1595 PF12760.7 CEG42873.1 - 0.045 13.7 2.1 0.11 12.5 2.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YhfH PF14149.6 CEG42873.1 - 0.27 11.2 4.5 2 8.5 0.1 2.6 2 0 0 2 2 2 0 YhfH-like protein STATa_Ig PF18214.1 CEG42873.1 - 0.39 10.7 6.0 0.4 10.7 0.3 2.4 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain SNARE_assoc PF09335.11 CEG42874.1 - 5.6e-11 43.0 3.4 4.9e-10 39.9 1.8 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein RhodobacterPufX PF11511.8 CEG42874.1 - 4.9 6.8 6.4 12 5.6 0.1 3.5 3 1 1 4 4 4 0 Intrinsic membrane protein PufX ParA PF10609.9 CEG42875.1 - 3.9e-82 275.4 0.0 5.2e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 CEG42875.1 - 1.3e-12 48.1 0.0 4.1e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CbiA PF01656.23 CEG42875.1 - 2.4e-12 47.0 0.0 4.4e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEG42875.1 - 2.4e-10 40.6 0.2 8.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CEG42875.1 - 8.9e-08 31.7 0.2 4.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 ATPase MipZ FeS_assembly_P PF01883.19 CEG42875.1 - 2.2e-07 31.0 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ArsA_ATPase PF02374.15 CEG42875.1 - 9.5e-06 25.0 0.2 0.0049 16.1 0.2 2.6 2 0 0 2 2 2 2 Anion-transporting ATPase Fer4_NifH PF00142.18 CEG42875.1 - 2.4e-05 23.9 0.2 7.3e-05 22.3 0.2 1.7 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 CEG42875.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 CEG42875.1 - 0.017 14.6 0.1 0.057 12.9 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 CEG42875.1 - 0.1 11.6 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Lactamase_B_6 PF16661.5 CEG42880.1 - 5.6e-56 189.0 0.0 1e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CEG42880.1 - 6.9e-17 62.1 0.7 3.1e-15 56.8 0.0 2.9 2 1 1 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Ribosomal_L25p PF01386.19 CEG42880.1 - 1.2e-15 57.7 0.0 2.9e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal L25p family Beta-Casp PF10996.8 CEG42880.1 - 1.4e-15 57.5 0.0 3.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Ribosomal_TL5_C PF14693.6 CEG42880.1 - 4.5e-15 55.8 0.0 1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain RMMBL PF07521.12 CEG42880.1 - 1.9e-08 34.1 0.0 4.9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CEG42880.1 - 1.8e-05 24.8 0.1 3.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEG42880.1 - 0.00046 19.8 0.2 0.0047 16.5 0.1 2.7 4 0 0 4 4 4 1 Beta-lactamase superfamily domain NifZ PF04319.13 CEG42880.1 - 0.21 11.4 0.4 20 5.0 0.0 3.7 5 0 0 5 5 5 0 NifZ domain HMG_box PF00505.19 CEG42881.1 - 1.4e-20 73.4 0.1 1.4e-20 73.4 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 CEG42881.1 - 1.2e-13 51.1 0.0 3.4e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.10 CEG42881.1 - 5.7e-13 49.3 0.1 5.7e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 HMG-box domain Histone PF00125.24 CEG42881.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CHDNT PF08073.12 CEG42881.1 - 0.0028 17.6 0.0 0.009 16.0 0.0 1.8 2 0 0 2 2 2 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 CEG42881.1 - 0.055 13.4 0.5 0.055 13.4 0.5 2.2 2 1 1 3 3 3 0 HMG (high mobility group) box 5 AAA PF00004.29 CEG42882.1 - 4.1e-35 121.1 0.0 7.4e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG42882.1 - 1.4e-07 31.2 0.1 4.5e-07 29.6 0.1 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEG42882.1 - 0.00023 21.2 0.0 0.0073 16.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEG42882.1 - 0.00031 20.5 0.1 0.00065 19.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG42882.1 - 0.00032 21.0 1.0 0.03 14.6 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CEG42882.1 - 0.00044 20.7 1.8 0.0079 16.6 0.2 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CEG42882.1 - 0.00085 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEG42882.1 - 0.00094 18.5 0.3 0.0018 17.5 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CEG42882.1 - 0.0011 19.5 0.0 0.0035 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CEG42882.1 - 0.0027 17.9 0.0 0.0063 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEG42882.1 - 0.0055 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CEG42882.1 - 0.0064 15.9 0.2 0.019 14.3 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CEG42882.1 - 0.011 14.9 0.1 0.025 13.6 0.1 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 CEG42882.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEG42882.1 - 0.015 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CEG42882.1 - 0.019 14.9 0.5 0.044 13.7 0.5 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CEG42882.1 - 0.02 15.3 0.3 0.078 13.4 0.1 2.1 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 CEG42882.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 CEG42882.1 - 0.034 14.2 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG42882.1 - 0.035 14.1 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEG42882.1 - 0.042 13.3 0.2 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 CEG42882.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Zeta_toxin PF06414.12 CEG42882.1 - 0.093 12.0 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CEG42882.1 - 0.23 11.0 0.3 0.74 9.4 0.2 1.9 2 0 0 2 2 2 0 AAA domain TruB_N PF01509.18 CEG42883.1 - 7.8e-51 172.4 0.0 1.1e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CEG42883.1 - 0.0028 17.7 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 CEG42883.1 - 0.0096 15.9 0.1 0.18 11.9 0.0 3.0 3 1 0 3 3 3 1 Pseudouridine synthase II TruB, C-terminal DKCLD PF08068.12 CEG42883.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 DKCLD (NUC011) domain DUF2807 PF10988.8 CEG42884.1 - 0.032 14.0 0.1 0.033 14.0 0.1 1.0 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF1764 PF08576.10 CEG42884.1 - 0.091 13.7 0.0 0.14 13.1 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Metallophos PF00149.28 CEG42885.1 - 1.1e-07 32.6 7.3 3.2e-07 31.1 7.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GRA6 PF05084.13 CEG42885.1 - 0.019 15.0 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) SpoIIIAH PF12685.7 CEG42885.1 - 0.069 13.0 2.1 0.1 12.4 2.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4950 PF16308.5 CEG42885.1 - 0.14 12.1 8.0 0.15 12.0 7.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4950) DUF4834 PF16118.5 CEG42885.1 - 0.18 12.8 0.3 0.39 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 CEG42885.1 - 1.7 8.6 5.2 0.68 9.8 2.3 1.8 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SSP160 PF06933.11 CEG42885.1 - 1.9 6.6 15.2 2.7 6.1 15.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 CEG42885.1 - 3.6 5.9 11.8 5.6 5.3 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF223 PF02721.14 CEG42888.1 - 0.012 15.8 0.4 0.015 15.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF223 Pkinase PF00069.25 CEG42890.1 - 4.5e-37 127.9 0.0 5.4e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42890.1 - 1.8e-36 125.8 0.0 2.2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG42890.1 - 5.6e-06 25.8 0.0 8.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG42890.1 - 0.00021 21.3 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG42890.1 - 0.0029 16.6 0.1 0.038 13.0 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CEG42890.1 - 0.007 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 CEG42890.1 - 0.051 13.2 0.1 0.16 11.6 0.0 1.7 1 1 1 2 2 2 0 RIO1 family ubiquitin PF00240.23 CEG42891.1 - 0.011 15.4 0.6 0.073 12.8 0.0 2.3 2 1 0 2 2 2 0 Ubiquitin family CbiA PF01656.23 CEG42891.1 - 0.021 14.8 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Amidohydro_1 PF01979.20 CEG42892.1 - 1.2e-61 209.0 0.7 1.7e-61 208.5 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 CEG42892.1 - 7.3e-53 178.0 2.4 7.3e-53 178.0 2.4 2.1 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 CEG42892.1 - 1.2e-43 147.4 0.9 3.3e-43 146.0 0.9 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 CEG42892.1 - 3.1e-38 129.7 0.0 7.9e-38 128.4 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 CEG42892.1 - 1.3e-05 24.9 0.0 0.0092 15.5 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Phage_head_fibr PF11133.8 CEG42892.1 - 0.0051 16.3 0.2 1.3 8.3 0.1 2.2 2 0 0 2 2 2 2 Head fiber protein RyR PF02026.16 CEG42893.1 - 3.2e-09 36.8 0.0 3.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RyR domain Kinesin PF00225.23 CEG42895.1 - 5.9e-85 285.1 0.1 8.5e-85 284.6 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG42895.1 - 4.5e-15 55.9 0.0 8.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CEG42895.1 - 0.00095 19.6 0.6 0.0048 17.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain SlyX PF04102.12 CEG42895.1 - 0.012 16.2 0.3 0.054 14.1 0.3 2.1 1 0 0 1 1 1 0 SlyX ISET-FN3_linker PF16625.5 CEG42895.1 - 0.044 14.3 0.4 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO Bac_DnaA PF00308.18 CEG42895.1 - 0.045 13.6 0.2 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.12 CEG42895.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CEG42895.1 - 0.097 12.9 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG42895.1 - 0.51 10.4 4.3 2.2 8.3 0.0 3.3 4 0 0 4 4 4 0 Helicase HerA, central domain DUF2397 PF09660.10 CEG42895.1 - 0.69 8.8 5.2 4.9 5.9 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) UPF0242 PF06785.11 CEG42895.1 - 4.1 7.5 10.0 0.34 11.0 4.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Aminotran_1_2 PF00155.21 CEG42896.1 - 3.8e-39 134.9 0.0 5.6e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_psq PF05225.16 CEG42896.1 - 1.3e-12 47.2 0.1 2.9e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 CEG42896.1 - 0.073 12.9 0.9 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 CEG42896.1 - 0.12 12.6 0.4 0.3 11.2 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DotA PF11388.8 CEG42896.1 - 0.13 12.5 1.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Phagosome trafficking protein DotA Pkinase PF00069.25 CEG42897.1 - 1.2e-66 224.8 0.0 1.7e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42897.1 - 2.8e-33 115.3 0.0 4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG42897.1 - 5.6e-08 32.4 0.0 9.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CEG42897.1 - 3.5e-07 30.8 0.2 1.2e-06 29.1 0.2 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.24 CEG42897.1 - 0.00069 19.6 4.4 0.002 18.1 1.8 2.9 3 1 1 4 4 4 1 PX domain FTA2 PF13095.6 CEG42897.1 - 0.03 13.9 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DLH PF01738.18 CEG42897.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Kdo PF06293.14 CEG42897.1 - 0.078 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nipped-B_C PF12830.7 CEG42899.1 - 3.6e-43 147.7 1.1 5e-41 140.8 0.0 3.5 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CEG42899.1 - 8.3e-12 45.2 0.2 2.6e-11 43.6 0.2 2.0 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 CEG42899.1 - 1e-06 28.9 7.6 0.17 11.9 0.0 5.3 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEG42899.1 - 2.8e-05 24.0 8.6 0.1 12.9 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CEG42899.1 - 0.0043 17.5 0.1 9.1 6.9 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 CEG42899.1 - 0.0043 17.4 0.7 2.1 8.8 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats Epimerase PF01370.21 CEG42900.1 - 5.9e-49 166.7 0.0 7.4e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEG42900.1 - 1.4e-34 120.0 0.0 2.1e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CEG42900.1 - 5.8e-23 81.3 0.0 9e-23 80.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEG42900.1 - 2.2e-13 50.0 0.0 2e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 CEG42900.1 - 2.1e-11 43.5 0.6 2.6e-09 36.6 0.6 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CEG42900.1 - 1.3e-10 41.4 0.0 1.8e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CEG42900.1 - 1.1e-08 34.5 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CEG42900.1 - 0.0011 18.5 0.1 0.043 13.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 CEG42900.1 - 0.092 13.0 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 CEG42900.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PAC2 PF09754.9 CEG42900.1 - 0.15 12.1 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 PAC2 family 2-Hacid_dh_C PF02826.19 CEG42900.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GTP_CH_N PF12471.8 CEG42902.1 - 5.7e-80 267.6 0.0 8.4e-80 267.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CEG42902.1 - 4.6e-12 45.8 0.0 7.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ank_4 PF13637.6 CEG42910.1 - 1.6e-17 63.6 7.9 0.00033 21.1 0.1 6.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG42910.1 - 1.4e-15 57.6 8.7 1.2e-06 29.0 1.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG42910.1 - 7e-14 50.6 9.0 0.11 13.1 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CEG42910.1 - 3.1e-13 49.5 9.7 0.012 16.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CEG42910.1 - 8e-12 45.2 9.9 0.0018 18.5 0.2 5.4 3 3 1 4 4 4 4 Ankyrin repeats (many copies) Peptidase_M1 PF01433.20 CEG42911.1 - 3e-41 141.4 0.0 4.9e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CEG42911.1 - 2.4e-21 75.9 0.1 4.4e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CEG42911.1 - 4.1e-13 49.9 0.0 6.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Rad17 PF03215.15 CEG42912.1 - 1.4e-17 64.2 0.0 3.3e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CEG42912.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CEG42912.1 - 0.00057 20.1 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG42912.1 - 0.00074 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEG42912.1 - 0.00091 19.7 0.0 0.0029 18.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CEG42912.1 - 0.0024 17.7 0.0 0.024 14.4 0.0 2.5 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CEG42912.1 - 0.0046 17.3 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RsgA_GTPase PF03193.16 CEG42912.1 - 0.0052 16.7 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CEG42912.1 - 0.0058 17.2 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEG42912.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 CEG42912.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG42912.1 - 0.027 14.4 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CEG42912.1 - 0.031 14.8 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 CEG42912.1 - 0.073 13.5 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CEG42912.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CEG42912.1 - 0.092 12.0 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CEG42912.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 CEG42912.1 - 0.093 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CEG42912.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEG42912.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 CEG42912.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 CEG42912.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Hydrolase_4 PF12146.8 CEG42913.1 - 7.3e-43 146.5 0.0 9.4e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG42913.1 - 2.2e-07 31.7 0.1 2.9e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CEG42913.1 - 0.0083 15.7 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CEG42913.1 - 0.026 14.2 1.0 1.1 8.8 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CEG42913.1 - 0.13 12.1 0.1 19 5.0 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CEG42913.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase RNA_Me_trans PF04252.13 CEG42916.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Retrotran_gag_2 PF14223.6 CEG42923.1 - 4.4e-18 65.3 0.1 8.5e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CEG42923.1 - 1.6e-16 60.6 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG42923.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CEG42923.1 - 0.017 15.2 2.2 0.041 14.0 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEG42923.1 - 0.02 14.7 3.7 0.043 13.6 3.6 1.7 1 1 0 1 1 1 0 Zinc knuckle DDE_Tnp_1_2 PF13586.6 CEG42923.1 - 0.082 13.3 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Nrap_D5 PF17406.2 CEG42926.1 - 0.075 12.8 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 BclA_C PF18573.1 CEG42929.1 - 0.0032 17.4 1.3 0.0055 16.6 1.3 1.3 1 0 0 1 1 1 1 BclA C-terminal domain RPW8 PF05659.11 CEG42929.1 - 0.028 14.1 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Csm1_N PF18504.1 CEG42929.1 - 0.036 14.4 0.6 0.098 13.0 0.6 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain RTC4 PF14474.6 CEG42929.1 - 0.089 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RTC4-like domain C1q PF00386.21 CEG42929.1 - 0.098 12.9 0.1 0.19 11.9 0.1 1.5 2 0 0 2 2 2 0 C1q domain DUF4041 PF13250.6 CEG42929.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) PKcGMP_CC PF16808.5 CEG42929.1 - 0.22 11.4 4.1 0.42 10.5 4.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 CEG42929.1 - 0.4 10.5 2.8 0.5 10.2 1.2 1.9 2 0 0 2 2 2 0 Septum formation initiator RPW8 PF05659.11 CEG42932.1 - 0.0069 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 TAN PF11640.8 CEG42932.1 - 0.041 14.0 0.8 5.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Spc42p PF11544.8 CEG42932.1 - 0.19 11.8 3.5 0.53 10.3 3.4 1.8 1 1 0 1 1 1 0 Spindle pole body component Spc42p Ribosomal_L44 PF00935.19 CEG42934.1 - 1.5e-32 111.9 14.7 2.6e-32 111.1 14.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 YbgS PF13985.6 CEG42934.1 - 1 9.7 7.1 0.15 12.3 2.9 1.8 1 1 1 2 2 2 0 YbgS-like protein Hydrolase_4 PF12146.8 CEG42935.1 - 2.4e-13 49.9 0.1 3.7e-11 42.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG42935.1 - 7.8e-08 33.2 0.3 1.7e-07 32.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEG42935.1 - 2.2e-07 30.8 0.1 2.8e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CEG42935.1 - 4.7e-07 29.7 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) zf-RanBP PF00641.18 CEG42935.1 - 0.00021 20.6 1.3 0.0005 19.3 1.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PhoPQ_related PF10142.9 CEG42935.1 - 0.027 13.1 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Elicitin PF00964.17 CEG42936.1 - 0.0023 18.0 0.4 0.0056 16.8 0.4 1.7 1 0 0 1 1 1 1 Elicitin Retrotran_gag_2 PF14223.6 CEG42938.1 - 3.4e-21 75.4 3.0 4.2e-21 75.1 3.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG42938.1 - 2.9e-06 27.1 2.5 4.3e-06 26.5 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle GP57 PF17594.2 CEG42939.1 - 0.037 13.8 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 PX PF00787.24 CEG42940.1 - 4.7e-06 26.5 0.2 1.3e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 PX domain zf-Di19 PF05605.12 CEG42940.1 - 0.11 12.8 0.1 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF953 PF06110.11 CEG42941.1 - 5.7e-26 90.5 0.0 1.5e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) IBD PF10416.9 CEG42941.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD DUF953 PF06110.11 CEG42942.1 - 2.5e-22 78.7 0.0 3.5e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) DUF953 PF06110.11 CEG42943.1 - 2.7e-61 204.5 0.0 9.5e-24 83.3 0.0 4.3 4 0 0 4 4 4 4 Eukaryotic protein of unknown function (DUF953) C1_2 PF03107.16 CEG42943.1 - 0.0028 17.9 2.4 0.98 9.8 0.3 3.4 3 0 0 3 3 3 1 C1 domain PyrI_C PF02748.15 CEG42943.1 - 0.065 13.2 1.0 8.3 6.4 0.0 3.7 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Wzy_C PF04932.15 CEG42943.1 - 0.093 12.4 0.7 0.21 11.2 0.0 1.9 3 0 0 3 3 3 0 O-Antigen ligase PilJ_C PF18223.1 CEG42943.1 - 0.13 12.7 3.8 0.21 12.1 0.1 3.1 3 0 0 3 3 3 0 Pili PilJ C-terminal domain START PF01852.19 CEG42944.1 - 2.9e-09 36.6 0.0 7.9e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 START domain PDZ PF00595.24 CEG42944.1 - 0.0017 18.7 0.0 0.0054 17.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain TBCA PF02970.16 CEG42944.1 - 0.15 12.4 1.1 0.5 10.7 1.1 1.8 1 0 0 1 1 1 0 Tubulin binding cofactor A Pkinase PF00069.25 CEG42945.1 - 1.6e-50 171.9 0.0 2.6e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42945.1 - 7e-49 166.4 0.0 1.2e-48 165.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Barttin PF15462.6 CEG42945.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Halogen_Hydrol PF10112.9 CEG42945.1 - 0.058 13.4 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF953 PF06110.11 CEG42946.1 - 2.5e-24 85.2 0.0 3.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) PUCC PF03209.15 CEG42946.1 - 0.16 10.9 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 PUCC protein Brix PF04427.18 CEG42947.1 - 2.1e-33 116.1 0.0 2.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain ArfGap PF01412.18 CEG42948.1 - 2.9e-33 114.4 0.8 4.8e-33 113.7 0.0 1.8 2 0 0 2 2 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CEG42948.1 - 3.3e-25 89.2 2.5 4.4e-13 49.5 0.1 2.3 2 0 0 2 2 2 2 BAR domain of APPL family PH PF00169.29 CEG42948.1 - 1.8e-09 38.1 0.0 3.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 CEG42948.1 - 5.6e-06 26.5 0.1 1.6e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG42948.1 - 0.0013 19.3 0.0 0.0048 17.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG42948.1 - 0.0034 17.9 0.0 0.013 16.1 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) BAR PF03114.18 CEG42948.1 - 0.0045 16.7 1.1 0.025 14.2 0.1 2.3 2 1 0 2 2 2 1 BAR domain SlyX PF04102.12 CEG42948.1 - 0.059 14.0 1.0 0.67 10.6 0.2 3.1 2 0 0 2 2 2 0 SlyX Ank PF00023.30 CEG42948.1 - 0.064 13.7 0.1 0.38 11.3 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat PH_9 PF15410.6 CEG42948.1 - 0.07 13.5 0.0 0.22 11.9 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain GHMP_kinases_C PF08544.13 CEG42948.1 - 0.17 12.2 0.3 0.65 10.4 0.1 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal Vps5 PF09325.10 CEG42948.1 - 2.2 7.8 5.8 15 5.1 0.0 2.8 2 1 1 3 3 3 0 Vps5 C terminal like zf-B_box PF00643.24 CEG42948.1 - 3.1 8.0 6.8 1.2 9.4 1.9 2.4 2 0 0 2 2 2 0 B-box zinc finger Ion_trans PF00520.31 CEG42949.1 - 7.1e-80 267.8 47.0 4.4e-43 147.3 13.2 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 CEG42949.1 - 8.9e-12 43.7 1.0 3.9e-06 26.0 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG42949.1 - 1.1e-07 31.1 0.1 0.0092 15.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CEG42949.1 - 2.9e-07 30.8 0.0 6.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.12 CEG42949.1 - 1.8e-06 26.9 9.2 1.8e-06 26.9 9.2 3.6 2 1 0 2 2 2 1 Polycystin cation channel EF-hand_5 PF13202.6 CEG42949.1 - 2.6e-06 26.7 0.8 0.041 13.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG42949.1 - 3e-05 23.8 0.1 8.8e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair TssO PF17561.2 CEG42949.1 - 0.0018 18.4 1.4 0.49 10.5 0.0 2.7 2 0 0 2 2 2 1 Type VI secretion system, TssO DUF2973 PF11189.8 CEG42949.1 - 0.0046 17.0 2.5 2.3 8.4 0.1 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2973) DNApol_Exo PF18136.1 CEG42949.1 - 0.025 13.7 0.5 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain COX16 PF14138.6 CEG42949.1 - 0.29 11.7 2.1 11 6.6 0.1 3.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Shisa PF13908.6 CEG42949.1 - 0.36 11.1 1.3 29 4.8 0.3 2.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 CEG42949.1 - 0.4 10.5 2.0 3.9 7.4 0.2 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 CEG42949.1 - 0.58 8.9 5.8 2.2 6.9 0.8 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 CEG42949.1 - 3.2 7.5 6.7 11 5.8 0.4 2.8 2 1 1 3 3 3 0 Transmembrane protein 51 Baculo_11_kDa PF06143.11 CEG42949.1 - 7.1 6.3 10.8 1.5 8.5 0.4 3.8 4 0 0 4 4 4 0 Baculovirus 11 kDa family CLIP1_ZNF PF16641.5 CEG42950.1 - 0.03 14.2 0.2 0.051 13.5 0.2 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle RVT_2 PF07727.14 CEG42951.1 - 9.8e-11 41.8 1.6 5.1e-09 36.1 1.6 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tubulin PF00091.25 CEG42952.1 - 1.8e-45 155.6 0.0 2.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain cwf21 PF08312.12 CEG42953.1 - 1.2e-05 25.4 5.0 1.2e-05 25.4 5.0 3.1 2 0 0 2 2 2 1 cwf21 domain CobU PF02283.16 CEG42953.1 - 0.095 12.3 1.3 0.27 10.8 1.3 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cu-oxidase PF00394.22 CEG42954.1 - 2.3e-30 105.8 0.0 7.4e-29 100.9 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEG42954.1 - 1.2e-29 102.7 0.4 2.8e-29 101.5 0.4 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEG42954.1 - 2.4e-07 30.6 1.0 1.7e-05 24.6 1.5 3.0 2 1 0 2 2 2 1 Multicopper oxidase WD40 PF00400.32 CEG42956.1 - 0.011 16.6 0.2 0.4 11.6 0.0 2.7 2 1 0 2 2 2 0 WD domain, G-beta repeat FIBP PF05427.11 CEG42958.1 - 2.9e-09 36.7 0.1 3.9e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) DUF3053 PF11254.8 CEG42958.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Pox_A3L PF05288.11 CEG42958.1 - 0.12 12.4 0.5 0.62 10.1 0.1 2.4 3 0 0 3 3 3 0 Poxvirus A3L Protein Pkinase PF00069.25 CEG42959.1 - 7e-33 114.1 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG42959.1 - 7e-12 45.2 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 CEG42961.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 zf-C2H2 PF00096.26 CEG42971.1 - 0.0065 16.9 0.5 0.018 15.5 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG42971.1 - 0.1 13.5 0.3 0.51 11.3 0.3 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF179 PF02622.15 CEG42972.1 - 1.5e-29 103.0 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Complex1_LYR PF05347.15 CEG42972.1 - 0.0045 17.0 0.5 0.16 12.1 0.0 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_11 PF08241.12 CEG42973.1 - 6.7e-10 39.5 0.0 3e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG42973.1 - 2.1e-09 38.0 0.1 2.8e-08 34.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG42973.1 - 2.1e-09 37.3 0.0 4.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG42973.1 - 5.7e-05 23.0 0.0 0.0002 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG42973.1 - 0.0016 19.1 0.3 0.047 14.4 0.0 3.2 3 1 0 3 3 3 1 Methyltransferase domain Drf_FH3 PF06367.16 CEG42973.1 - 0.023 14.3 0.7 0.054 13.1 0.7 1.6 2 0 0 2 2 2 0 Diaphanous FH3 Domain DOT1 PF08123.13 CEG42974.1 - 1.9e-08 34.1 0.1 3e-08 33.4 0.1 1.3 1 1 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 CEG42974.1 - 1.5e-05 24.4 0.8 0.00012 21.5 0.2 2.0 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 CEG42974.1 - 1.6e-05 24.7 0.1 3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 CEG42974.1 - 0.00011 21.4 0.6 0.055 12.5 0.0 2.4 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEG42974.1 - 0.00075 20.2 1.8 0.15 12.8 1.8 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG42974.1 - 0.0047 17.5 1.6 0.07 13.8 1.6 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG42974.1 - 0.0055 16.5 1.7 0.15 11.9 1.7 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG42974.1 - 0.0059 16.4 0.2 0.0095 15.7 0.2 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CEG42974.1 - 0.0088 15.9 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CEG42974.1 - 0.011 15.3 0.9 0.021 14.4 0.3 1.6 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW IQ PF00612.27 CEG42974.1 - 0.022 14.5 0.2 0.045 13.5 0.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif PrmA PF06325.13 CEG42974.1 - 0.035 13.5 0.2 0.048 13.1 0.2 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TFIIE_alpha PF02002.17 CEG42978.1 - 3.8e-14 52.4 1.3 8.6e-14 51.3 1.3 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit HypA PF01155.19 CEG42978.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C5-epim_C PF06662.13 CEG42980.1 - 0.14 11.7 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus LRR_8 PF13855.6 CEG42981.1 - 3.3e-13 49.2 11.8 1.5e-08 34.3 1.8 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CEG42981.1 - 1e-11 44.9 13.9 5.2e-07 29.9 1.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG42981.1 - 9.6e-07 28.5 10.6 0.38 11.5 0.0 5.4 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 CEG42981.1 - 0.00018 21.3 16.2 0.79 9.9 0.4 5.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 CEG42981.1 - 0.00031 20.3 4.5 0.00042 19.9 4.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 CEG42981.1 - 0.047 13.6 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) V-ATPase_H_N PF03224.14 CEG42982.1 - 2.8e-06 26.9 15.9 0.013 14.8 5.0 5.2 3 1 1 4 4 4 3 V-ATPase subunit H HEAT_EZ PF13513.6 CEG42982.1 - 8e-06 26.2 17.3 0.014 15.9 0.0 7.1 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 CEG42982.1 - 3.7e-05 24.0 21.7 0.19 12.1 0.1 8.1 7 1 1 9 9 9 2 HEAT repeats RICTOR_V PF14668.6 CEG42982.1 - 7.7e-05 22.9 10.7 0.5 10.7 0.0 5.9 5 1 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 CEG42982.1 - 0.00047 20.1 64.3 0.2 11.8 0.1 14.0 17 0 0 17 17 17 5 Armadillo/beta-catenin-like repeat DUF3731 PF12531.8 CEG42982.1 - 0.66 9.7 3.2 3.7 7.3 0.1 3.3 3 1 0 3 3 3 0 DNA-K related protein XhlA PF10779.9 CEG42985.1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Sel1 PF08238.12 CEG42987.1 - 1.5e-11 44.6 1.0 4.4e-08 33.5 0.3 2.2 2 0 0 2 2 2 2 Sel1 repeat TPR_16 PF13432.6 CEG42987.1 - 0.065 13.9 0.3 0.097 13.3 0.3 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-trcl PF13451.6 CEG42988.1 - 0.063 13.2 1.5 0.13 12.2 1.5 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain C2 PF00168.30 CEG42992.1 - 1.1e-08 35.2 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain McrBC PF10117.9 CEG42994.1 - 0.00038 19.7 0.5 0.00057 19.1 0.5 1.2 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component BNR_6 PF15899.5 CEG42994.1 - 0.056 13.5 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 BNR-Asp box repeat MSP7_C PF12948.7 CEG42994.1 - 0.4 11.4 8.5 0.35 11.5 1.0 3.4 3 2 0 3 3 3 0 MSP7-like protein C-terminal domain NAM-associated PF14303.6 CEG42996.1 - 0.13 13.0 0.1 0.2 12.4 0.1 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3674 PF12426.8 CEG43002.1 - 0.15 12.1 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase SCIMP PF15050.6 CEG43003.1 - 0.03 14.8 0.1 0.03 14.8 0.1 2.4 2 0 0 2 2 2 0 SCIMP protein Thioredoxin_8 PF13905.6 CEG43004.1 - 0.00022 21.5 0.0 0.00047 20.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Patatin PF01734.22 CEG43005.1 - 8.6e-10 39.1 4.8 0.00011 22.5 3.0 2.3 1 1 1 2 2 2 2 Patatin-like phospholipase Mito_fiss_reg PF05308.11 CEG43006.1 - 0.071 13.2 3.4 0.13 12.3 3.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Retrotran_gag_2 PF14223.6 CEG43007.1 - 8.6e-14 51.4 0.1 1.5e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG43007.1 - 0.00067 19.6 2.4 0.0013 18.7 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Gal11_ABD1 PF18535.1 CEG43007.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) rve PF00665.26 CEG43008.1 - 1e-05 25.7 0.0 2.9e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain Mannosyl_trans3 PF11051.8 CEG43009.1 - 2.1e-22 79.8 0.0 3.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative PH PF00169.29 CEG43012.1 - 0.02 15.4 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 PH domain Nexin_C PF08628.12 CEG43012.1 - 0.028 15.0 0.1 0.053 14.1 0.1 1.5 1 0 0 1 1 1 0 Sorting nexin C terminal DUF5330 PF17264.2 CEG43014.1 - 0.066 13.2 0.0 0.085 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5330) PRANC PF09372.10 CEG43017.1 - 0.022 15.1 0.1 0.026 14.8 0.1 1.1 1 0 0 1 1 1 0 PRANC domain DUF4905 PF16248.5 CEG43017.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) RT_RNaseH_2 PF17919.1 CEG43018.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase AA_permease_2 PF13520.6 CEG43019.1 - 1.4e-45 155.9 39.2 2e-45 155.4 39.2 1.2 1 0 0 1 1 1 1 Amino acid permease WBP-1 PF11669.8 CEG43019.1 - 3 8.5 4.5 32 5.2 0.1 3.6 4 0 0 4 4 4 0 WW domain-binding protein 1 DUF3169 PF11368.8 CEG43019.1 - 9 5.7 15.8 0.43 10.0 5.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) PPR_long PF17177.4 CEG43021.1 - 5.2e-73 244.9 2.2 7.9e-73 244.3 2.2 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PRORP PF16953.5 CEG43021.1 - 2.1e-51 174.8 1.9 4.2e-51 173.8 1.9 1.5 1 0 0 1 1 1 1 Protein-only RNase P PPR PF01535.20 CEG43021.1 - 7.4e-14 51.0 0.3 0.04 14.2 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_3 PF13812.6 CEG43021.1 - 3.5e-11 43.0 0.2 0.016 15.3 0.2 3.6 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 CEG43021.1 - 2.4e-09 37.2 0.3 0.011 15.9 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family RNase_Zc3h12a PF11977.8 CEG43021.1 - 0.0001 22.1 0.7 0.00042 20.1 0.7 2.0 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain 4HB_MCP_1 PF12729.7 CEG43021.1 - 0.14 11.7 3.1 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction Waikav_capsid_1 PF12264.8 CEG43024.1 - 0.028 13.9 0.1 0.075 12.5 0.1 1.6 1 1 1 2 2 2 0 Waikavirus capsid protein 1 NIT PF08376.10 CEG43025.1 - 0.061 13.8 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing MIP-T3_C PF17749.1 CEG43027.1 - 0.00093 19.2 2.5 0.0014 18.6 2.1 1.4 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region zf-BED PF02892.15 CEG43028.1 - 3e-05 23.9 3.5 0.00018 21.4 3.8 2.2 1 1 1 2 2 2 1 BED zinc finger Tom22 PF04281.13 CEG43028.1 - 0.038 13.8 3.5 0.87 9.4 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 GHMP_kinases_N PF00288.26 CEG43029.1 - 1.5e-12 47.5 2.8 3.3e-12 46.4 2.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEG43029.1 - 1.6e-05 25.2 0.0 5.3e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Halogen_Hydrol PF10112.9 CEG43029.1 - 0.048 13.7 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein GalKase_gal_bdg PF10509.9 CEG43029.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Sigma70_ner PF04546.13 CEG43029.1 - 0.12 12.3 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4473 PF14747.6 CEG43029.1 - 0.17 12.5 0.1 12 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DnaJ PF00226.31 CEG43030.1 - 4.4e-25 87.6 1.0 8.8e-25 86.6 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Helicase_C PF00271.31 CEG43031.1 - 9.3e-14 51.7 0.2 4.5e-13 49.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CEG43031.1 - 1.1e-13 51.4 2.8 1.6e-13 50.9 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 CEG43031.1 - 7.2e-09 35.6 0.0 2.2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CEG43031.1 - 3.6e-05 24.0 0.1 0.00012 22.3 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold dsRBD2 PF17842.1 CEG43031.1 - 0.00031 21.0 0.9 0.0029 17.8 0.0 3.1 3 0 0 3 3 3 1 Double-stranded RNA binding domain 2 AAA_22 PF13401.6 CEG43031.1 - 0.00099 19.4 0.2 0.0046 17.2 0.2 2.1 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 CEG43031.1 - 0.0064 16.7 0.3 0.044 14.0 0.2 2.5 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 CEG43031.1 - 0.015 14.7 0.0 0.055 12.8 0.0 2.0 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 CEG43031.1 - 0.028 14.9 0.0 0.028 14.9 0.0 4.0 3 1 1 4 4 2 0 AAA domain T2SSE PF00437.20 CEG43031.1 - 0.031 13.4 0.0 0.097 11.7 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein dsrm PF00035.26 CEG43031.1 - 0.043 14.5 0.0 0.15 12.8 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif AAA_29 PF13555.6 CEG43031.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro81C PF17652.1 CEG43032.1 - 4.6e-119 397.7 1.5 8.1e-119 396.9 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG43032.1 - 3.3e-45 154.6 1.2 4.9e-45 154.1 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Pkinase PF00069.25 CEG43033.1 - 8.5e-68 228.6 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43033.1 - 1.8e-29 102.8 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG43033.1 - 1.6e-08 34.2 0.0 2.2e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEG43033.1 - 1.2e-05 24.8 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG43033.1 - 0.00013 22.0 0.0 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_8 PF13855.6 CEG43034.1 - 2.8e-14 52.6 18.0 5.2e-09 35.7 5.0 4.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CEG43034.1 - 3.7e-13 49.4 33.8 1e-07 32.1 5.6 5.6 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG43034.1 - 1.5e-08 34.4 12.1 4.6e-07 29.5 0.5 3.4 2 2 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CEG43034.1 - 0.02 14.9 9.5 6.4 7.1 0.4 5.2 4 0 0 4 4 4 0 Leucine Rich repeat YabA PF06156.13 CEG43034.1 - 0.14 12.8 13.5 0.61 10.8 3.9 2.9 1 1 1 2 2 2 0 Initiation control protein YabA MbeD_MobD PF04899.12 CEG43034.1 - 0.16 12.1 6.5 7 6.8 0.4 3.4 3 0 0 3 3 3 0 MbeD/MobD like LRR_1 PF00560.33 CEG43034.1 - 0.2 12.3 15.1 9.4 7.2 0.1 6.5 5 1 0 5 5 5 0 Leucine Rich Repeat BLOC1_2 PF10046.9 CEG43034.1 - 0.56 10.6 9.8 1.6 9.0 4.0 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.18 CEG43034.1 - 0.68 10.2 12.6 1 9.6 0.6 3.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 CEG43034.1 - 2.5 8.3 10.4 8 6.6 0.5 3.3 3 0 0 3 3 3 0 Basic region leucine zipper ZapB PF06005.12 CEG43034.1 - 3.1 8.3 16.5 23 5.5 1.8 3.3 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CEG43034.1 - 3.2 7.6 14.5 12 5.8 4.9 3.3 1 1 2 3 3 3 0 Septum formation initiator FlxA PF14282.6 CEG43034.1 - 6.4 6.8 14.3 30 4.7 14.0 2.2 1 1 0 1 1 1 0 FlxA-like protein Med9 PF07544.13 CEG43034.1 - 9.7 6.4 16.3 3.4 7.8 8.5 3.5 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 LRR_6 PF13516.6 CEG43035.1 - 3.4e-15 54.7 9.1 0.0066 16.4 0.1 7.9 8 0 0 8 8 8 3 Leucine Rich repeat EF-hand_7 PF13499.6 CEG43035.1 - 4.7e-14 52.6 7.3 1.6e-06 28.4 3.7 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG43035.1 - 5.1e-14 50.9 6.1 4.5e-05 23.1 0.4 4.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CEG43035.1 - 3.8e-12 44.8 15.8 0.00028 20.2 0.2 4.7 3 1 1 4 4 4 4 EF hand EF-hand_5 PF13202.6 CEG43035.1 - 1.8e-09 36.6 9.2 0.00076 18.9 0.2 3.7 3 0 0 3 3 3 2 EF hand LRR_1 PF00560.33 CEG43035.1 - 0.00022 21.3 2.6 46 5.1 0.2 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4476 PF14771.6 CEG43035.1 - 0.02 15.2 0.1 0.56 10.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) EF-hand_9 PF14658.6 CEG43035.1 - 0.026 14.9 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain LRR_8 PF13855.6 CEG43035.1 - 0.05 13.4 10.0 0.82 9.5 1.9 5.4 4 2 2 6 6 6 0 Leucine rich repeat EF-hand_8 PF13833.6 CEG43035.1 - 0.15 11.9 9.4 0.73 9.7 0.2 3.9 2 1 3 5 5 5 0 EF-hand domain pair LRR_4 PF12799.7 CEG43035.1 - 0.72 10.4 13.9 7.6 7.1 1.7 4.7 4 2 0 4 4 3 0 Leucine Rich repeats (2 copies) EF-hand_10 PF14788.6 CEG43035.1 - 2.7 7.9 8.1 19 5.2 0.3 4.4 2 1 2 4 4 4 0 EF hand Chromo PF00385.24 CEG43040.1 - 3e-07 30.2 0.2 5.1e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RasGAP PF00616.19 CEG43043.1 - 1.1e-25 90.6 0.3 8.6e-23 81.1 0.0 3.3 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase PH PF00169.29 CEG43043.1 - 5e-07 30.2 0.0 5.8e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 PH domain SpoOE-like PF09388.10 CEG43043.1 - 0.038 13.9 0.6 0.088 12.7 0.6 1.7 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Glucan_synthase PF02364.15 CEG43044.1 - 5.4e-194 646.7 28.6 2.8e-175 584.8 14.8 3.7 2 1 1 3 3 3 2 1,3-beta-glucan synthase component SKN1 PF03935.15 CEG43044.1 - 9.3e-75 251.9 2.9 1.8e-74 251.0 2.9 1.4 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FKS1_dom1 PF14288.6 CEG43044.1 - 1.1e-18 67.8 1.1 1.5e-17 64.1 1.1 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4203 PF13886.6 CEG43044.1 - 0.00016 21.4 25.9 0.00016 21.4 25.9 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4203) RB_A PF01858.17 CEG43045.1 - 4.3e-57 193.1 1.3 9.6e-57 192.0 1.3 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 CEG43045.1 - 3e-29 101.7 0.1 6.9e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 CEG43045.1 - 8.8e-19 67.4 1.2 2.6e-17 62.6 0.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) Rb_C PF08934.10 CEG43045.1 - 2.6e-06 27.3 0.2 2.6e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 Rb C-terminal domain Pkinase PF00069.25 CEG43046.1 - 5.6e-57 193.1 0.0 8.4e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43046.1 - 1.2e-33 116.5 0.0 1.8e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG43046.1 - 1.1e-08 35.5 0.1 1.4e-07 32.0 0.1 2.6 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CEG43046.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG43046.1 - 0.0093 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bac_surface_Ag PF01103.23 CEG43046.1 - 0.022 14.2 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Surface antigen Seadorna_VP7 PF07387.11 CEG43046.1 - 0.028 13.5 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_18 PF13238.6 CEG43049.1 - 4.2e-07 30.6 0.0 9.9e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG43049.1 - 6e-07 29.7 0.0 9.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEG43049.1 - 5.3e-06 26.8 0.2 1.4e-05 25.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CEG43049.1 - 0.007 15.7 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 KaiC CoaE PF01121.20 CEG43049.1 - 0.009 15.7 0.0 0.036 13.7 0.0 2.0 2 0 0 2 2 2 1 Dephospho-CoA kinase dNK PF01712.19 CEG43049.1 - 0.013 15.4 0.5 0.13 12.1 0.5 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase Thymidylate_kin PF02223.17 CEG43049.1 - 0.057 13.1 0.4 3.4 7.3 0.0 3.0 1 1 3 4 4 4 0 Thymidylate kinase NB-ARC PF00931.22 CEG43049.1 - 0.065 12.4 0.1 0.18 10.9 0.0 1.7 2 1 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 CEG43049.1 - 0.078 13.2 0.1 0.38 11.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 CEG43049.1 - 0.084 13.3 0.0 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEG43049.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEG43049.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NPP1 PF05630.11 CEG43052.1 - 2.1e-44 152.0 0.0 2.8e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF2103 PF09876.9 CEG43053.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) Pyr_redox_2 PF07992.14 CEG43054.1 - 1.3e-07 31.2 0.1 4.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Asp_Glu_race PF01177.22 CEG43054.1 - 0.037 13.9 0.1 0.09 12.6 0.1 1.6 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase UDPG_MGDP_dh_N PF03721.14 CEG43054.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PFK PF00365.20 CEG43054.1 - 0.07 12.4 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase Gag_p30 PF02093.16 CEG43054.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Gag P30 core shell protein UPF0139 PF03669.13 CEG43055.1 - 7.9e-27 93.0 0.0 2.5e-26 91.4 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF4485 PF14846.6 CEG43055.1 - 5.6e-15 55.2 0.4 1.8e-14 53.5 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) COMPASS-Shg1 PF05205.12 CEG43055.1 - 0.9 10.3 8.2 0.32 11.7 3.7 2.4 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DivIC PF04977.15 CEG43055.1 - 2.6 7.9 11.8 0.17 11.7 4.0 3.0 3 1 0 3 3 3 0 Septum formation initiator WW PF00397.26 CEG43056.1 - 9.3e-18 64.0 10.7 1.7e-08 34.4 4.5 2.4 2 0 0 2 2 2 2 WW domain IQ PF00612.27 CEG43056.1 - 2.3e-15 54.9 64.3 0.0023 17.6 0.5 11.7 11 0 0 11 11 11 7 IQ calmodulin-binding motif LRR_4 PF12799.7 CEG43056.1 - 4e-13 49.3 15.3 0.0024 18.3 4.0 7.1 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG43056.1 - 1.9e-12 46.1 29.6 0.2 11.8 0.2 10.5 10 0 0 10 10 10 3 Leucine Rich repeat Glyco_hyd_101C PF17451.2 CEG43056.1 - 2.9e-05 24.3 4.5 0.037 14.3 1.0 2.7 2 0 0 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain LRR_1 PF00560.33 CEG43056.1 - 7.8e-05 22.7 19.7 0.88 10.4 0.1 9.2 9 0 0 9 9 9 1 Leucine Rich Repeat Plus-3 PF03126.18 CEG43056.1 - 0.048 14.2 1.1 0.15 12.6 1.1 1.8 1 0 0 1 1 1 0 Plus-3 domain MiAMP1 PF09117.10 CEG43056.1 - 0.52 10.6 4.7 1.5 9.1 0.3 3.2 2 1 1 3 3 3 0 MiAMP1 LRR_8 PF13855.6 CEG43056.1 - 4 7.3 8.0 43 4.0 2.7 4.5 3 1 1 5 5 5 0 Leucine rich repeat CENP-F_leu_zip PF10473.9 CEG43056.1 - 6.5 6.8 20.3 0.14 12.2 6.9 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Aldedh PF00171.22 CEG43057.1 - 1.6e-161 537.9 0.2 1.9e-161 537.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEG43057.1 - 4.7e-05 22.9 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) FAD_binding_1 PF00667.20 CEG43058.1 - 3.3e-43 147.8 0.0 7.5e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEG43058.1 - 1.8e-26 93.0 0.0 4.6e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CEG43058.1 - 8.8e-11 42.4 0.0 2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FANCF PF11107.8 CEG43058.1 - 0.00077 18.8 2.5 0.0013 18.0 2.5 1.3 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Flavodoxin_5 PF12724.7 CEG43058.1 - 0.04 14.2 0.0 2.2 8.5 0.0 2.8 2 1 1 3 3 3 0 Flavodoxin domain Bcr-Abl_Oligo PF09036.10 CEG43058.1 - 0.09 12.8 0.0 26 4.9 0.0 3.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Flavodoxin_3 PF12641.7 CEG43058.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain HECT PF00632.25 CEG43059.1 - 2.8e-69 233.9 0.0 3.7e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Actin PF00022.19 CEG43060.1 - 1.6e-37 129.1 0.0 2e-31 109.0 0.0 3.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 CEG43060.1 - 0.026 13.4 0.1 0.053 12.3 0.1 1.4 1 0 0 1 1 1 0 MreB/Mbl protein XendoU PF09412.10 CEG43062.1 - 1.3e-93 313.0 0.0 1.6e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU IQ PF00612.27 CEG43062.1 - 0.0028 17.3 1.3 0.0083 15.8 1.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif mRNA_cap_enzyme PF01331.19 CEG43064.1 - 6.1e-27 94.7 0.0 1e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CEG43064.1 - 0.00045 20.8 0.0 0.0023 18.6 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain zf-CCCH PF00642.24 CEG43064.1 - 0.0095 15.8 7.5 0.019 14.9 7.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DNA_ligase_A_M PF01068.21 CEG43064.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Pectinesterase PF01095.19 CEG43066.1 - 2.5e-46 157.8 2.6 3.5e-46 157.3 2.6 1.2 1 0 0 1 1 1 1 Pectinesterase DUF1983 PF09327.11 CEG43066.1 - 0.096 12.8 0.4 0.29 11.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) Kinesin PF00225.23 CEG43067.1 - 1.2e-101 340.0 0.1 1.2e-101 340.0 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG43067.1 - 9.2e-22 77.6 3.1 3.7e-21 75.6 0.0 3.1 3 1 0 3 3 3 1 Microtubule binding FAM60A PF15396.6 CEG43067.1 - 0.0053 16.8 2.8 0.0053 16.8 2.8 2.3 1 1 1 2 2 2 1 Protein Family FAM60A DUF3763 PF12592.8 CEG43067.1 - 0.3 11.2 4.4 0.22 11.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) PPR_long PF17177.4 CEG43068.1 - 7.8e-06 25.4 0.3 0.0058 16.0 0.1 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEG43068.1 - 3.6e-05 23.7 0.0 0.34 11.3 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.6 CEG43068.1 - 0.00022 21.4 0.4 0.12 12.5 0.1 3.8 3 1 2 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CEG43068.1 - 0.0013 18.8 0.0 0.026 14.6 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_12 PF13424.6 CEG43068.1 - 0.027 14.8 1.4 5 7.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43068.1 - 0.034 14.7 8.2 0.13 12.8 0.9 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat APP_E2 PF12925.7 CEG43068.1 - 0.05 13.3 0.3 0.1 12.3 0.3 1.5 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein TPR_14 PF13428.6 CEG43068.1 - 0.11 13.3 4.9 21 6.3 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 CEG43068.1 - 0.52 10.0 2.1 8.9 6.1 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Pectinesterase PF01095.19 CEG43070.1 - 5.7e-45 153.3 2.5 7.7e-45 152.9 2.5 1.1 1 0 0 1 1 1 1 Pectinesterase CBS PF00571.28 CEG43071.1 - 1.1e-30 105.8 11.1 2.5e-07 31.0 0.7 5.5 4 2 0 4 4 4 4 CBS domain DisA_N PF02457.16 CEG43071.1 - 0.011 15.3 1.8 2.9 7.5 0.0 3.0 3 0 0 3 3 3 0 DisA bacterial checkpoint controller nucleotide-binding Cation_efflux PF01545.21 CEG43072.1 - 3.4e-49 167.3 5.5 4.1e-49 167.0 5.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF805 PF05656.14 CEG43072.1 - 0.0012 19.2 1.3 0.0036 17.7 1.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF805) FYVE PF01363.21 CEG43073.1 - 3.4e-05 23.9 7.6 9.8e-05 22.4 7.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 CEG43073.1 - 0.00097 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 CEG43073.1 - 0.015 15.6 5.0 0.015 15.6 5.0 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 CEG43074.1 - 1.3e-11 44.4 9.6 3.7e-11 43.0 9.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 CEG43074.1 - 0.6 10.0 2.9 1.5 8.7 2.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NinF PF05810.12 CEG43074.1 - 1.1 9.2 4.1 1.7 8.5 2.7 2.1 2 0 0 2 2 2 0 NinF protein zf-CRD PF17979.1 CEG43074.1 - 8 6.5 8.8 1.2 9.3 3.7 2.2 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions RGCC PF15151.6 CEG43077.1 - 0.068 13.4 1.5 0.093 13.0 0.5 1.9 1 1 0 1 1 1 0 Response gene to complement 32 protein family SelK_SelG PF10961.8 CEG43077.1 - 0.16 12.6 0.7 0.31 11.7 0.2 1.8 1 1 1 2 2 2 0 Selenoprotein SelK_SelG DUF3977 PF13122.6 CEG43079.1 - 0.095 12.9 0.5 0.31 11.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3977) Ntox43 PF15537.6 CEG43082.1 - 0.1 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial toxin 43 Thioredoxin PF00085.20 CEG43083.1 - 5.9e-28 96.9 0.0 1.4e-27 95.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG43083.1 - 1.1e-05 25.8 0.1 0.00018 21.9 0.0 2.4 2 1 0 2 2 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CEG43083.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 CEG43083.1 - 0.00021 20.7 0.0 0.00027 20.4 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 CEG43083.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CEG43083.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CEG43083.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CEG43083.1 - 0.0076 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 CEG43083.1 - 0.0094 16.1 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like DUF836 PF05768.14 CEG43083.1 - 0.015 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 CEG43083.1 - 0.039 14.3 0.0 0.94 9.8 0.0 2.5 1 1 2 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 CEG43083.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 CEG43083.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin DUF4201 PF13870.6 CEG43084.1 - 0.0018 18.0 5.0 0.0018 18.0 5.0 3.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4201) GAS PF13851.6 CEG43084.1 - 0.05 13.0 30.0 0.58 9.5 6.5 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GOLD_2 PF13897.6 CEG43084.1 - 0.13 12.8 5.6 2.1 8.9 0.1 3.3 2 1 1 3 3 3 0 Golgi-dynamics membrane-trafficking Ctr PF04145.15 CEG43085.1 - 0.0032 18.1 0.9 0.0034 18.0 0.9 1.2 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.32 CEG43087.1 - 0.0017 19.2 2.7 1.2 10.1 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat UCH PF00443.29 CEG43089.1 - 4.6e-29 101.7 0.0 5.8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG43089.1 - 1.5e-11 44.5 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ZapB PF06005.12 CEG43090.1 - 0.043 14.3 1.3 0.14 12.7 1.3 1.8 1 0 0 1 1 1 0 Cell division protein ZapB LRS4 PF10422.9 CEG43090.1 - 0.043 13.4 4.6 0.064 12.8 4.6 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 HTH_Tnp_IS630 PF01710.16 CEG43090.1 - 0.074 13.1 0.7 0.13 12.3 0.7 1.3 1 0 0 1 1 1 0 Transposase bZIP_2 PF07716.15 CEG43090.1 - 0.12 12.5 0.6 0.31 11.1 0.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper cNMP_binding PF00027.29 CEG43091.1 - 1.8e-18 66.4 0.1 5.4e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain UCH PF00443.29 CEG43092.1 - 7.6e-70 235.3 0.0 9.5e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEG43092.1 - 6.8e-18 65.1 0.0 1.8e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 CEG43092.1 - 1e-11 45.0 0.7 1.4e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 CEG43092.1 - 8.7e-09 35.3 13.1 8.7e-09 35.3 13.1 3.3 3 0 0 3 3 3 1 MYND finger SNF2_N PF00176.23 CEG43093.1 - 7.8e-49 166.3 0.0 1e-47 162.6 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Xpo1 PF08389.12 CEG43093.1 - 6.8e-11 42.4 1.6 1.3e-10 41.5 0.2 2.3 2 0 0 2 2 2 1 Exportin 1-like protein Helicase_C PF00271.31 CEG43093.1 - 7.7e-11 42.3 0.0 2.8e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG43093.1 - 0.022 14.8 0.0 0.15 12.0 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PAC2 PF09754.9 CEG43093.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 PAC2 family EptA_B_N PF08019.12 CEG43094.1 - 0.016 15.1 0.3 0.028 14.3 0.1 1.3 1 1 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF3638 PF12340.8 CEG43096.1 - 0.00044 19.7 0.0 0.00046 19.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) FYVE_2 PF02318.16 CEG43097.1 - 0.037 14.2 4.3 0.096 12.9 4.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG43097.1 - 0.061 13.5 8.8 0.16 12.1 8.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger Myb_DNA-binding PF00249.31 CEG43098.1 - 6.8e-39 131.8 8.1 3.4e-13 49.6 0.6 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG43098.1 - 1.5e-32 111.6 3.1 1.5e-12 47.6 0.2 4.0 2 1 2 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEG43098.1 - 0.021 14.9 0.2 3.1 7.9 0.0 3.3 3 1 1 4 4 4 0 SLIDE Myb_DNA-bind_4 PF13837.6 CEG43098.1 - 0.16 12.4 1.8 4.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CEG43099.1 - 2.1e-40 136.6 8.0 8.2e-13 48.3 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG43099.1 - 1e-34 118.6 2.5 2.6e-14 53.2 0.9 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEG43099.1 - 1.4e-05 25.1 0.0 1.7 8.7 0.0 3.5 2 1 1 3 3 3 3 SLIDE MADF_DNA_bdg PF10545.9 CEG43099.1 - 0.0059 16.9 2.4 8.3 6.8 0.0 3.4 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 CEG43099.1 - 0.013 15.6 1.2 5.8 7.1 0.2 3.4 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 CEG43099.1 - 0.063 13.2 0.2 0.66 9.9 0.0 2.5 2 1 1 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 CEG43099.1 - 1.1 9.7 8.0 2.4 8.6 0.6 3.6 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain FKBP_C PF00254.28 CEG43100.1 - 6.4e-48 161.0 0.1 6.5e-30 103.3 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase ChapFlgA PF13144.6 CEG43100.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation TP_methylase PF00590.20 CEG43101.1 - 9.8e-39 133.5 0.1 1.3e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases K-box PF01486.17 CEG43102.1 - 9.6e-06 25.7 0.9 2.7e-05 24.3 0.9 1.7 1 0 0 1 1 1 1 K-box region rRNA_proc-arch PF13234.6 CEG43102.1 - 0.074 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 rRNA-processing arch domain Ribonuc_red_lgC PF02867.15 CEG43103.1 - 6.7e-186 618.9 0.0 8.7e-186 618.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEG43103.1 - 1.1e-22 79.9 0.0 4.1e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEG43103.1 - 9.8e-19 67.7 0.0 2.8e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Myosin_head PF00063.21 CEG43105.1 - 1.4e-223 744.0 0.2 1.8e-223 743.6 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEG43105.1 - 1.6e-16 58.5 37.3 0.00057 19.5 0.2 7.9 7 0 0 7 7 7 6 IQ calmodulin-binding motif Myosin_N PF02736.19 CEG43105.1 - 3.1e-06 26.9 0.0 5.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CEG43105.1 - 0.082 13.2 0.1 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG43105.1 - 0.12 12.8 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CEG43105.1 - 0.14 12.7 0.0 0.48 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEG43105.1 - 0.14 12.5 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase WD40 PF00400.32 CEG43106.1 - 2.4e-09 37.6 6.4 0.26 12.2 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43106.1 - 0.0029 17.8 0.0 0.14 12.5 0.0 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CEG43106.1 - 0.14 12.1 0.4 3.4 7.7 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Astro_capsid_p PF12226.8 CEG43106.1 - 4.2 6.4 12.5 7.6 5.6 12.5 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 CEG43106.1 - 8.1 5.7 20.8 16 4.7 20.8 1.5 1 0 0 1 1 1 0 NOA36 protein TLD PF07534.16 CEG43107.1 - 2.4e-31 108.8 0.0 4.1e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 TLD Mg_trans_NIPA PF05653.14 CEG43108.1 - 8.1e-32 110.5 14.9 1.1e-31 110.0 14.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.6 CEG43108.1 - 0.00055 19.6 0.4 0.00055 19.6 0.4 2.2 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter EamA PF00892.20 CEG43108.1 - 0.00063 19.9 6.9 0.00063 19.9 6.9 3.1 2 1 0 2 2 2 1 EamA-like transporter family TMEM234 PF10639.9 CEG43108.1 - 0.0037 17.3 6.9 0.005 16.9 1.2 2.4 2 0 0 2 2 2 1 Putative transmembrane family 234 EF-hand_7 PF13499.6 CEG43109.1 - 1e-11 45.1 0.0 0.019 15.4 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 CEG43109.1 - 2.8e-05 23.3 0.1 11 5.8 0.0 5.5 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 CEG43109.1 - 0.00014 21.5 0.4 9.2 6.5 0.0 4.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CEG43109.1 - 0.0046 16.8 0.0 8.6 6.3 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair RIIa PF02197.17 CEG43109.1 - 0.095 12.4 0.2 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit PIP5K PF01504.18 CEG43110.1 - 5.1e-68 229.3 0.0 7.4e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG43110.1 - 2.4e-05 23.8 10.8 3.7e-05 23.1 10.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 CEG43110.1 - 0.044 13.1 10.5 0.076 12.3 10.5 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Wzy_C PF04932.15 CEG43110.1 - 0.24 11.0 2.0 1.4 8.6 0.5 2.2 2 0 0 2 2 2 0 O-Antigen ligase ERGIC_N PF13850.6 CEG43110.1 - 0.25 11.7 2.4 3.2 8.1 0.0 3.1 4 0 0 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kazal_2 PF07648.15 CEG43120.1 - 1.2e-09 38.1 4.9 2.1e-09 37.4 4.9 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG43120.1 - 2.1e-07 30.8 3.5 3.7e-07 30.1 3.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain PBP_sp32 PF07222.12 CEG43121.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 WD40 PF00400.32 CEG43122.1 - 9.9e-61 200.3 17.5 1.5e-10 41.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43122.1 - 4.5e-16 58.9 0.1 0.00062 20.0 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG43122.1 - 3.9e-06 26.1 2.7 2 7.3 0.0 4.5 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG43122.1 - 1.9e-05 23.5 4.0 0.13 10.9 0.1 3.2 1 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CEG43122.1 - 7.3e-05 22.7 0.0 0.0047 16.8 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Palm_thioest PF02089.15 CEG43123.1 - 0.0031 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CEG43123.1 - 0.012 15.2 0.3 0.06 13.0 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG43123.1 - 0.043 14.4 0.2 0.16 12.6 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family F_actin_cap_B PF01115.17 CEG43124.1 - 1.4e-94 316.2 0.0 1.6e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit RNA_pol_I_A49 PF06870.12 CEG43125.1 - 4.3e-78 262.9 3.0 4.9e-78 262.7 3.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pam16 PF03656.13 CEG43125.1 - 0.11 12.5 1.8 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Pam16 DUF2178 PF09946.9 CEG43126.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) TNFR_16_TM PF18422.1 CEG43126.1 - 0.17 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain MIF4G PF02854.19 CEG43129.1 - 1e-22 80.8 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 CEG43129.1 - 0.023 14.3 1.1 0.042 13.5 0.0 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region La PF05383.17 CEG43130.1 - 2.8e-16 59.3 0.2 4.6e-16 58.6 0.2 1.3 1 0 0 1 1 1 1 La domain Polyketide_cyc PF03364.20 CEG43130.1 - 0.019 15.2 0.3 0.047 13.9 0.0 1.7 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF3522 PF12036.8 CEG43133.1 - 5.4e-24 85.5 8.9 7e-24 85.2 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF1275 PF06912.11 CEG43133.1 - 0.039 13.9 3.5 0.5 10.3 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Pox_A14 PF05767.12 CEG43133.1 - 0.25 11.5 4.5 0.92 9.7 0.2 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 CEBP_ZZ PF16366.5 CEG43135.1 - 0.00027 21.1 23.7 0.017 15.4 6.7 2.5 1 1 1 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 CEG43135.1 - 0.0016 18.6 9.2 0.0016 18.6 9.2 2.6 1 1 1 2 2 2 1 B-box zinc finger Med25_SD1 PF11235.8 CEG43135.1 - 1.5 9.2 9.8 0.11 12.8 3.8 2.2 2 1 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Mis14 PF08641.12 CEG43135.1 - 4.1 7.7 7.0 0.23 11.8 0.2 2.4 3 0 0 3 3 3 0 Kinetochore protein Mis14 like RAI16-like PF10257.9 CEG43136.1 - 2.1e-43 148.6 2.7 3.7e-43 147.8 2.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MCD_N PF17408.2 CEG43136.1 - 0.016 15.3 0.1 0.043 13.9 0.1 1.8 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain NFACT-C PF11923.8 CEG43139.1 - 0.015 15.2 0.5 3.3 7.7 0.0 3.4 3 0 0 3 3 3 0 NFACT protein C-terminal domain Phage_tail_L PF05100.12 CEG43139.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein L Kunitz_BPTI PF00014.23 CEG43141.1 - 0.089 13.0 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Glyco_hydro_42M PF08532.10 CEG43142.1 - 0.049 13.1 0.0 0.056 12.9 0.0 1.0 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain STAS_2 PF13466.6 CEG43143.1 - 0.054 13.8 0.6 0.08 13.3 0.6 1.2 1 0 0 1 1 1 0 STAS domain Tmemb_14 PF03647.13 CEG43144.1 - 1.5e-13 51.3 2.1 1.8e-13 51.0 2.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 CEG43144.1 - 0.0039 17.5 0.9 0.0047 17.2 0.9 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 zf-rbx1 PF12678.7 CEG43144.1 - 0.045 14.1 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain Phage_holin_3_6 PF07332.11 CEG43144.1 - 0.1 12.6 1.2 0.15 12.1 1.2 1.3 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-ANAPC11 PF12861.7 CEG43144.1 - 0.17 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger His_Phos_2 PF00328.22 CEG43145.1 - 1e-78 265.4 0.4 1.1e-74 252.1 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CEG43145.1 - 9.3e-38 128.3 0.0 2.1e-37 127.1 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CEG43145.1 - 0.0007 19.2 0.0 0.0041 16.7 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SR-25 PF10500.9 CEG43145.1 - 0.15 11.7 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_A_type_inc PF04508.12 CEG43146.1 - 0.002 17.9 0.9 1.1 9.3 0.0 3.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Csm1_N PF18504.1 CEG43146.1 - 0.065 13.6 0.9 0.065 13.6 0.9 5.8 3 2 5 8 8 8 0 Csm1 N-terminal domain Spc29 PF17082.5 CEG43146.1 - 4.4 7.1 18.4 1.5 8.6 1.6 2.9 1 1 2 3 3 3 0 Spindle Pole Component 29 DUF1943 PF09172.11 CEG43146.1 - 5.6 6.1 6.7 0.59 9.3 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) HEAT PF02985.22 CEG43147.1 - 6.1e-09 35.4 4.1 0.091 13.1 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CEG43147.1 - 2.6e-08 34.1 2.2 0.0064 16.9 0.1 4.3 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CEG43147.1 - 5.8e-08 33.0 9.8 1.2e-05 25.4 0.1 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CEG43147.1 - 0.002 18.3 1.5 1 9.6 0.1 3.8 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CEG43147.1 - 0.0039 17.8 0.1 0.32 11.6 0.0 3.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CEG43147.1 - 0.011 14.4 13.9 0.0049 15.5 6.8 3.1 2 2 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 CEG43147.1 - 0.023 15.2 3.8 5 7.7 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Xpo1 PF08389.12 CEG43147.1 - 0.14 12.2 5.4 0.48 10.5 0.5 3.5 3 0 0 3 3 3 0 Exportin 1-like protein CMD PF02627.20 CEG43149.1 - 0.013 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family LOR PF04525.12 CEG43153.1 - 6.1e-05 22.7 0.0 0.00019 21.1 0.0 1.7 2 0 0 2 2 2 1 LURP-one-related Homoserine_dh PF00742.19 CEG43155.1 - 2.7e-55 186.9 0.9 4.2e-55 186.3 0.9 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CEG43155.1 - 3.9e-13 50.1 0.1 8e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2OG-FeII_Oxy_2 PF13532.6 CEG43157.1 - 0.0026 18.0 0.0 0.065 13.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FKBP_C PF00254.28 CEG43158.1 - 4.8e-36 123.0 0.0 5.6e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AgrB PF04647.15 CEG43159.1 - 0.0022 17.3 3.9 0.0086 15.4 2.6 2.0 2 0 0 2 2 2 1 Accessory gene regulator B MpPF26 PF07666.11 CEG43159.1 - 0.019 15.1 11.0 0.95 9.6 2.8 2.8 1 1 2 3 3 3 0 M penetrans paralogue family 26 DUF2621 PF11084.8 CEG43159.1 - 0.041 13.9 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) MARVEL PF01284.23 CEG43159.1 - 0.056 13.5 11.7 0.24 11.4 11.7 1.9 1 1 0 1 1 1 0 Membrane-associating domain DHHC PF01529.20 CEG43159.1 - 1.1 9.3 8.9 2.9 8.0 1.3 2.2 1 1 0 2 2 2 0 DHHC palmitoyltransferase DUF2207 PF09972.9 CEG43159.1 - 1.2 7.8 9.3 25 3.4 9.3 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RDD PF06271.12 CEG43159.1 - 2.7 8.2 9.2 2.1 8.6 2.2 2.3 1 1 1 2 2 2 0 RDD family ATP_bind_2 PF03668.15 CEG43160.1 - 0.19 11.0 0.3 0.29 10.4 0.3 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIB PF00382.19 CEG43161.1 - 1.2e-24 86.1 1.3 9.4e-12 44.8 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat GerE PF00196.19 CEG43161.1 - 0.071 12.7 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Erf4 PF10256.9 CEG43162.1 - 5.3e-05 23.3 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family UQ_con PF00179.26 CEG43163.1 - 7.5e-54 181.2 0.0 8.6e-54 181.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG43163.1 - 0.012 15.9 0.2 0.019 15.2 0.2 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CEG43163.1 - 0.047 13.4 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF3361 PF11841.8 CEG43164.1 - 0.00032 20.7 7.6 0.0079 16.2 3.1 3.7 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 CEG43164.1 - 0.00076 19.5 10.4 0.8 9.8 0.1 4.6 2 2 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 CEG43164.1 - 0.0016 18.4 4.9 1.8 8.7 0.2 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CDC14 PF08045.11 CEG43164.1 - 0.002 17.3 5.6 0.01 15.0 1.3 3.1 3 1 0 3 3 3 1 Cell division control protein 14, SIN component Sec8_exocyst PF04048.14 CEG43164.1 - 0.014 15.3 0.9 0.034 14.0 0.3 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Mis14 PF08641.12 CEG43164.1 - 0.041 14.2 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 Kinetochore protein Mis14 like UBA_3 PF09288.10 CEG43164.1 - 0.13 12.0 0.8 0.99 9.3 0.1 2.7 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain V-ATPase_H_C PF11698.8 CEG43164.1 - 2.4 8.3 4.6 38 4.4 0.1 3.3 3 0 0 3 3 3 0 V-ATPase subunit H Rgp1 PF08737.10 CEG43166.1 - 2.7e-24 86.1 0.0 2.6e-15 56.5 0.0 2.4 1 1 1 2 2 2 2 Rgp1 Arrestin_N PF00339.29 CEG43166.1 - 0.026 14.6 0.2 0.27 11.3 0.1 2.6 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain CTP_transf_like PF01467.26 CEG43167.1 - 1.8e-27 96.3 0.0 3.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF3511 PF12023.8 CEG43167.1 - 2.2 8.1 4.7 0.31 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) Tubulin PF00091.25 CEG43168.1 - 1.4e-34 120.0 0.2 1.4e-34 120.0 0.2 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 CEG43168.1 - 6.3e-28 96.9 0.2 1.6e-27 95.6 0.2 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Thioredoxin PF00085.20 CEG43169.1 - 6.3e-23 80.7 0.0 1.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 CEG43169.1 - 5.5e-17 61.5 0.1 2.7e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 CEG43169.1 - 7.1e-09 35.4 0.0 2.7e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Thioredoxin_2 PF13098.6 CEG43169.1 - 5e-06 26.9 0.0 2.9e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG43169.1 - 9.2e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CEG43169.1 - 0.023 14.9 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 CEG43169.1 - 0.058 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CEG43169.1 - 0.4 10.5 3.2 0.46 10.3 0.0 2.5 2 1 1 3 3 3 0 Thioredoxin DUF3435 PF11917.8 CEG43169.1 - 1.8 7.4 9.8 2.7 6.8 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) AAA_11 PF13086.6 CEG43169.1 - 3.3 7.4 9.7 7.3 6.3 9.7 1.5 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 CEG43169.1 - 4 6.4 7.9 7.4 5.6 7.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CEG43169.1 - 4.3 6.6 7.8 7.2 5.9 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kazal_2 PF07648.15 CEG43171.1 - 3.1e-09 36.8 6.1 6.1e-09 35.9 6.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG43171.1 - 2.5e-07 30.6 4.8 4.6e-07 29.8 4.8 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Memo PF01875.17 CEG43172.1 - 8.4e-78 261.2 0.0 1e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Transket_pyr PF02779.24 CEG43173.1 - 1.2e-58 197.7 0.0 2.1e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEG43173.1 - 3.3e-47 160.0 0.0 6.2e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 CEG43173.1 - 3.1e-46 157.7 0.0 4.9e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Hemopexin PF00045.19 CEG43173.1 - 0.094 12.7 0.5 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Hemopexin Vps16_C PF04840.12 CEG43174.1 - 9.4e-16 57.7 1.6 1.5e-15 57.1 1.6 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region p450 PF00067.22 CEG43175.1 - 1e-68 232.2 2.2 1.4e-68 231.8 2.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArsP_2 PF11449.8 CEG43175.1 - 0.15 11.3 0.4 0.22 10.7 0.4 1.2 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter CactinC_cactus PF09732.9 CEG43176.1 - 2.1 8.3 8.5 6.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Cactus-binding C-terminus of cactin protein ALMT PF11744.8 CEG43176.1 - 7.1 5.3 15.5 10 4.8 15.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter 2OG-FeII_Oxy PF03171.20 CEG43177.1 - 3.5e-05 24.2 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CEG43177.1 - 0.011 16.5 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PseudoU_synth_1 PF01416.20 CEG43178.1 - 1.1e-31 109.5 0.0 1.4e-28 99.5 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase TGase_elicitor PF16683.5 CEG43178.1 - 0.037 12.8 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase elicitor DNA_primase_lrg PF04104.14 CEG43179.1 - 4.3e-67 226.3 0.6 5.2e-67 226.1 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit YaiA PF16362.5 CEG43179.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 YaiA protein PP2C PF00481.21 CEG43180.1 - 9.2e-58 195.9 0.2 2e-57 194.8 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG43180.1 - 0.046 13.4 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C COQ9 PF08511.11 CEG43181.1 - 1.5e-35 120.8 0.6 2.9e-35 119.9 0.1 1.8 2 0 0 2 2 2 1 COQ9 Retrotran_gag_2 PF14223.6 CEG43182.1 - 0.039 13.6 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CRM1_C PF08767.11 CEG43184.1 - 8.4e-07 28.5 0.2 2.3e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 CRM1 C terminal IBN_N PF03810.19 CEG43184.1 - 0.1 12.5 2.1 0.19 11.7 0.4 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF3082 PF11282.8 CEG43186.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Nuc_sug_transp PF04142.15 CEG43187.1 - 1.8e-25 89.8 12.7 2.4e-25 89.4 12.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CEG43187.1 - 7.6e-10 38.5 9.0 2.4e-08 33.6 5.4 2.1 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport UAA PF08449.11 CEG43187.1 - 0.012 14.8 7.2 0.016 14.4 7.2 1.2 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.20 CEG43187.1 - 0.022 15.0 18.9 0.33 11.1 10.9 2.7 2 1 0 2 2 2 0 EamA-like transporter family FAD_binding_3 PF01494.19 CEG43188.1 - 1.8e-39 136.0 0.0 2.8e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CEG43189.1 - 1e-12 48.0 0.0 1.1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEG43189.1 - 0.00026 20.3 0.0 0.00027 20.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEG43189.1 - 0.00038 20.6 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG43189.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 CEG43189.1 - 0.0029 17.1 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 CEG43189.1 - 0.0089 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CEG43189.1 - 0.016 15.8 0.0 0.022 15.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEG43189.1 - 0.027 13.3 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 CEG43189.1 - 0.039 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CEG43189.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AMMECR1 PF01871.17 CEG43191.1 - 3.3e-44 150.4 0.0 3.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Kinesin PF00225.23 CEG43192.1 - 8e-102 340.6 6.1 1.7e-101 339.5 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG43192.1 - 2.1e-24 86.1 1.1 1.3e-23 83.6 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding Pkinase PF00069.25 CEG43193.1 - 2.6e-60 204.0 0.1 3.6e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43193.1 - 1.5e-32 112.9 0.1 2.2e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rogdi_lz PF10259.9 CEG43193.1 - 1e-13 51.4 0.0 2.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Pkinase_fungal PF17667.1 CEG43193.1 - 1.7e-08 33.7 0.1 3.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG43193.1 - 0.051 13.5 0.0 1.5 8.7 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 CEG43195.1 - 0.023 14.8 0.1 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Integrase zinc binding domain HisK_sensor PF18698.1 CEG43195.1 - 0.03 14.7 0.6 0.072 13.5 0.2 1.7 1 1 1 2 2 2 0 Histidine kinase sensor domain Peripla_BP_1 PF00532.21 CEG43195.1 - 0.084 12.3 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family HNH_2 PF13391.6 CEG43198.1 - 0.0033 17.5 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Kinesin PF00225.23 CEG43199.1 - 6.2e-105 350.8 0.0 6.2e-105 350.8 0.0 3.0 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CEG43199.1 - 4.2e-45 153.3 0.4 2.5e-44 150.8 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Mtc PF03820.17 CEG43199.1 - 2.9e-26 92.3 1.5 8.4e-26 90.7 1.5 1.7 1 0 0 1 1 1 1 Tricarboxylate carrier V-SNARE_C PF12352.8 CEG43199.1 - 1.7e-14 53.9 4.0 8.3e-14 51.6 4.0 2.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus WW PF00397.26 CEG43199.1 - 1.4e-08 34.7 3.1 3e-08 33.6 3.1 1.6 1 0 0 1 1 1 1 WW domain V-SNARE PF05008.15 CEG43199.1 - 0.00048 20.4 0.2 0.00048 20.4 0.2 5.5 5 1 0 5 5 5 1 Vesicle transport v-SNARE protein N-terminus DASH_Dad4 PF08650.10 CEG43199.1 - 0.15 12.0 2.2 2 8.4 0.4 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 PB1 PF00564.24 CEG43200.1 - 2.5e-06 27.3 0.1 4.7e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Dodecin PF07311.12 CEG43200.1 - 0.0026 18.0 0.1 0.0058 16.9 0.1 1.6 1 0 0 1 1 1 1 Dodecin DUF2992 PF11208.8 CEG43200.1 - 0.051 13.8 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) UBA PF00627.31 CEG43202.1 - 8.8e-07 28.7 3.9 0.023 14.6 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain DUF1421 PF07223.11 CEG43202.1 - 0.0038 17.0 0.1 0.16 11.8 0.1 2.6 2 0 0 2 2 2 1 UBA-like domain (DUF1421) SNF2_N PF00176.23 CEG43203.1 - 0.053 12.2 0.2 0.064 12.0 0.2 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HemY_N PF07219.13 CEG43203.1 - 0.13 12.5 1.7 0.17 12.1 0.2 2.1 2 1 0 2 2 2 0 HemY protein N-terminus Pyr_redox PF00070.27 CEG43205.1 - 0.0001 22.7 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEG43205.1 - 0.00038 19.8 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf_C2H2_ZHX PF18387.1 CEG43206.1 - 0.09 12.4 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CHY PF05495.12 CEG43207.1 - 2.6e-11 43.8 13.3 6e-11 42.7 13.3 1.6 1 1 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 CEG43207.1 - 0.045 13.3 7.1 1 9.0 0.3 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CEG43207.1 - 0.067 13.3 5.2 0.067 13.3 5.2 2.7 2 1 1 3 3 3 0 Zinc ribbon domain SIR2 PF02146.17 CEG43207.1 - 0.24 11.3 2.5 0.32 10.9 2.5 1.4 1 1 0 1 1 1 0 Sir2 family zf-C2H2_4 PF13894.6 CEG43207.1 - 1.9 9.6 15.7 3.1 8.9 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 CEG43209.1 - 0.0024 17.8 3.2 0.0092 15.9 3.2 2.0 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RNHCP PF12647.7 CEG43209.1 - 0.04 13.9 2.0 0.3 11.1 0.9 2.3 2 0 0 2 2 2 0 RNHCP domain DUF4110 PF13422.6 CEG43210.1 - 2.8e-12 46.5 2.3 2.9e-12 46.5 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) V_ATPase_prox PF18274.1 CEG43210.1 - 0.13 12.2 2.4 0.18 11.8 2.4 1.5 1 1 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe CbiA PF01656.23 CEG43211.1 - 0.0012 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CEG43211.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cyclin_N PF00134.23 CEG43213.1 - 8e-16 57.9 1.1 9e-14 51.3 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain UCH PF00443.29 CEG43214.1 - 4.2e-44 151.0 0.3 6.9e-44 150.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG43214.1 - 3.6e-10 40.0 7.1 2.9e-08 33.7 7.1 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GPI-anchored PF10342.9 CEG43218.1 - 0.097 13.4 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SNAPc_SNAP43 PF09808.9 CEG43220.1 - 6.3e-14 52.4 0.0 2.1e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MFS_1 PF07690.16 CEG43221.1 - 1.4e-33 116.3 16.9 1.4e-33 116.3 16.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 CEG43221.1 - 6.2e-07 28.4 6.8 0.0001 21.1 0.4 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 CEG43221.1 - 3.9e-06 26.0 13.9 0.00023 20.1 6.1 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 CEG43221.1 - 2.1e-05 23.5 16.6 0.0032 16.4 16.6 2.4 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 CEG43221.1 - 0.13 10.6 16.3 0.22 9.9 1.5 3.1 2 2 1 3 3 3 0 Transmembrane secretion effector Romo1 PF10247.9 CEG43221.1 - 0.83 10.1 6.6 35 4.9 0.6 3.6 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 SnoaL PF07366.12 CEG43222.1 - 0.012 15.4 0.0 0.056 13.2 0.0 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Robl_LC7 PF03259.17 CEG43224.1 - 3.1e-08 33.3 0.1 4.2e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain PPR_2 PF13041.6 CEG43225.1 - 0.0016 18.6 0.0 2 8.6 0.0 3.6 3 0 0 3 3 3 1 PPR repeat family CPSF100_C PF13299.6 CEG43225.1 - 0.14 12.3 3.1 0.38 10.9 3.1 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 CEG43225.1 - 2 7.7 22.3 0.01 15.3 12.9 1.8 2 0 0 2 2 2 0 SDA1 zf-C3HC4_3 PF13920.6 CEG43226.1 - 7.2e-07 29.0 8.7 7.2e-07 29.0 8.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG43226.1 - 0.0043 16.9 11.0 0.0043 16.9 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG43226.1 - 0.02 14.7 9.5 0.02 14.7 9.5 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG43226.1 - 0.026 14.7 10.6 0.026 14.7 10.6 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Abhydrolase_1 PF00561.20 CEG43233.1 - 2e-27 96.5 0.0 6e-24 85.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG43233.1 - 2.9e-21 77.1 0.0 3.5e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEG43233.1 - 2.1e-13 50.1 0.0 3.9e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 CEG43233.1 - 0.00027 20.9 0.1 0.0065 16.4 0.1 2.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 CEG43233.1 - 0.00083 19.1 0.0 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 CEG43233.1 - 0.0018 18.1 0.0 0.45 10.3 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CEG43233.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 CEG43233.1 - 0.0048 17.0 0.0 0.034 14.3 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 CEG43233.1 - 0.0078 15.7 0.0 0.074 12.6 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 CEG43233.1 - 0.012 15.2 0.0 0.05 13.1 0.0 2.2 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 CEG43233.1 - 0.02 14.4 0.0 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 CEG43233.1 - 0.021 14.6 0.0 0.25 11.0 0.0 2.2 1 1 0 1 1 1 0 PGAP1-like protein Lipase PF00151.19 CEG43233.1 - 0.039 13.2 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Lipase Palm_thioest PF02089.15 CEG43233.1 - 0.049 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 CEG43233.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold N_BRCA1_IG PF16158.5 CEG43234.1 - 5.1e-33 113.8 0.0 1.1e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 CEG43234.1 - 1.7e-08 34.3 0.6 2.7e-07 30.4 0.2 2.5 2 1 0 2 2 2 1 PB1 domain GerD PF17898.1 CEG43234.1 - 0.026 14.4 0.4 0.73 9.8 0.4 2.3 1 1 1 2 2 2 0 Spore germination GerD central core domain B2-adapt-app_C PF09066.10 CEG43235.1 - 5.7e-08 32.8 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain DUF599 PF04654.12 CEG43235.1 - 0.00066 19.2 0.6 0.0015 18.0 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF599 zf-RING_2 PF13639.6 CEG43236.1 - 1.4e-07 31.8 10.1 1.4e-07 31.8 10.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG43236.1 - 1.3e-05 25.3 11.4 1.3e-05 25.3 11.4 2.9 3 1 0 3 3 3 1 RING-H2 zinc finger domain PHD PF00628.29 CEG43236.1 - 0.00014 21.6 2.8 0.00014 21.6 2.8 3.0 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_2 PF13923.6 CEG43236.1 - 0.0002 21.1 10.1 0.00058 19.6 10.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG43236.1 - 0.00039 20.2 9.3 0.0013 18.5 9.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG43236.1 - 0.0033 17.1 10.9 0.0082 15.9 10.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger Reprolysin_2 PF13574.6 CEG43236.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-ANAPC11 PF12861.7 CEG43236.1 - 4.3 7.5 14.7 0.1 12.6 6.0 2.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEG43236.1 - 5.3 7.0 14.1 1.4 8.8 8.4 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-HC5HC2H PF13771.6 CEG43236.1 - 5.5 7.3 22.8 2 8.7 6.3 3.4 2 1 0 3 3 3 0 PHD-like zinc-binding domain zf-RING_10 PF16685.5 CEG43236.1 - 5.9 7.1 10.8 0.61 10.3 5.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-HC5HC2H_2 PF13832.6 CEG43236.1 - 7.3 6.8 19.5 0.44 10.7 4.8 2.9 2 1 1 3 3 3 0 PHD-zinc-finger like domain Imm30 PF15565.6 CEG43239.1 - 0.052 13.6 0.1 0.067 13.3 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 30 Pkinase PF00069.25 CEG43241.1 - 2.8e-47 161.3 0.0 1.4e-37 129.5 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43241.1 - 4.4e-24 85.2 0.0 6.4e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG43241.1 - 5.5e-06 25.4 0.0 8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG43241.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG43241.1 - 0.014 15.3 0.2 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG43241.1 - 0.062 12.6 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 CEG43241.1 - 0.11 12.1 0.1 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Bacteriocin_IIi PF11758.8 CEG43241.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin AIRS_C PF02769.22 CEG43242.1 - 5.2e-07 29.9 0.0 6.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain DUF3185 PF11381.8 CEG43243.1 - 0.046 13.7 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Ammonium_transp PF00909.21 CEG43247.1 - 2.1e-42 145.2 13.6 2.7e-42 144.9 13.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family GSHPx PF00255.19 CEG43247.1 - 8.4e-28 96.1 0.1 1.6e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEG43247.1 - 0.00046 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family CAP_GLY PF01302.25 CEG43248.1 - 8.4e-25 86.6 1.1 1.3e-24 85.9 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 CEG43248.1 - 2.6e-21 76.3 0.2 4.3e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal Cnd1 PF12717.7 CEG43248.1 - 0.028 14.5 0.1 11 6.0 0.0 2.5 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEG43248.1 - 0.15 12.4 1.6 0.9 10.0 0.2 3.0 3 0 0 3 3 3 0 HEAT repeat Ank_2 PF12796.7 CEG43249.1 - 5.8e-32 110.1 12.2 4.3e-06 27.2 0.2 8.2 4 3 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG43249.1 - 1.5e-17 63.7 15.6 0.00046 20.7 0.1 9.5 5 3 8 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG43249.1 - 2e-16 58.4 19.3 0.87 10.4 0.0 12.7 13 0 0 13 13 13 4 Ankyrin repeat Ank PF00023.30 CEG43249.1 - 5.5e-15 55.0 24.1 0.0019 18.6 0.1 10.4 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 CEG43249.1 - 8.5e-12 45.1 23.9 1.1 9.7 0.1 10.4 9 3 4 13 13 13 5 Ankyrin repeats (many copies) Ribosomal_S3Ae PF01015.18 CEG43250.1 - 7.4e-91 303.2 2.4 8.9e-91 302.9 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family AROS PF15684.5 CEG43251.1 - 0.0092 16.5 12.2 0.012 16.2 12.2 1.2 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DUF3300 PF11737.8 CEG43251.1 - 0.036 13.6 0.2 0.042 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF601 PF04642.12 CEG43251.1 - 0.055 13.0 6.4 0.066 12.7 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Ntox1 PF15500.6 CEG43251.1 - 0.23 11.8 2.3 0.26 11.7 1.2 1.7 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 LMBR1 PF04791.16 CEG43251.1 - 0.71 8.7 4.2 0.8 8.5 4.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SNARE PF05739.19 CEG43251.1 - 2.5 8.2 5.9 0.63 10.1 0.5 2.5 2 1 1 3 3 3 0 SNARE domain PAP2_C PF14360.6 CEG43252.1 - 2e-20 73.1 4.3 2e-20 73.1 4.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CEG43252.1 - 1.8e-05 24.5 5.0 1.8e-05 24.5 5.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CEG43252.1 - 0.11 12.1 14.0 0.036 13.8 8.9 2.3 1 1 1 2 2 2 0 PAP2 superfamily BAT2_N PF07001.11 CEG43253.1 - 1.2e-07 32.4 3.5 1.2e-07 32.4 3.5 4.4 3 1 2 5 5 5 1 BAT2 N-terminus HSF_DNA-bind PF00447.17 CEG43254.1 - 9.2e-22 77.5 0.9 1.3e-21 77.0 0.9 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding PP2C PF00481.21 CEG43255.1 - 6.8e-35 120.9 0.2 3.2e-34 118.8 0.2 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG43255.1 - 0.00013 21.7 2.1 0.00025 20.8 2.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3192 PF11399.8 CEG43255.1 - 0.068 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Retrotran_gag_2 PF14223.6 CEG43257.1 - 3e-25 88.5 5.3 3.3e-25 88.3 5.3 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MukF_M PF17192.4 CEG43257.1 - 0.012 15.4 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 0 MukF middle domain Retrotran_gag_3 PF14244.6 CEG43257.1 - 0.088 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CAP PF00188.26 CEG43260.1 - 5.8e-13 49.8 0.3 1.1e-12 48.8 0.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF5607 PF18355.1 CEG43260.1 - 0.016 15.6 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5607) Ubiquitin_2 PF14560.6 CEG43261.1 - 7.9e-13 48.7 0.1 2.5e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_4 PF12799.7 CEG43261.1 - 1.6e-11 44.2 12.3 0.023 15.1 0.2 5.5 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG43261.1 - 6.3e-10 38.7 10.3 0.00048 19.8 0.2 4.9 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CEG43261.1 - 1e-08 34.9 5.7 1.1e-05 25.0 0.1 3.3 1 1 1 3 3 3 3 Leucine-rich repeat ubiquitin PF00240.23 CEG43261.1 - 0.019 14.7 0.0 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin family LRR_6 PF13516.6 CEG43261.1 - 0.42 10.8 15.2 69 3.9 0.2 7.1 7 1 0 7 7 7 0 Leucine Rich repeat B12D PF06522.11 CEG43262.1 - 2.6e-22 78.4 0.0 3.6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RXLR PF16810.5 CEG43263.1 - 3.2e-16 60.0 0.0 3.8e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Viral_Beta_CD PF04530.12 CEG43264.1 - 0.17 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family FAM183 PF14886.6 CEG43265.1 - 5.3e-22 78.6 0.5 1.3e-21 77.4 0.5 1.7 1 0 0 1 1 1 1 FAM183A and FAM183B related Rhodanese PF00581.20 CEG43265.1 - 0.018 15.6 0.0 0.28 11.7 0.0 2.5 1 1 0 1 1 1 0 Rhodanese-like domain Ank_2 PF12796.7 CEG43266.1 - 1.4e-39 134.6 2.8 6.7e-12 45.8 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG43266.1 - 2.3e-36 123.7 12.3 1e-09 38.8 0.1 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG43266.1 - 2.5e-29 100.9 2.3 2.2e-08 34.2 0.0 6.8 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG43266.1 - 3.9e-26 88.2 3.2 3.7e-05 23.8 0.0 7.6 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 CEG43266.1 - 2.8e-22 78.1 2.1 2.9e-05 24.3 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat SAM_1 PF00536.30 CEG43266.1 - 4.4e-13 49.4 0.5 1.2e-12 48.1 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG43266.1 - 7.8e-11 41.9 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SNAP PF14938.6 CEG43267.1 - 9.6e-26 90.8 11.5 1.6e-25 90.1 11.5 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 CEG43267.1 - 0.02 14.6 0.5 0.24 11.1 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 CEG43267.1 - 0.096 13.0 0.3 9.8 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PDT PF00800.18 CEG43269.1 - 2.7e-06 27.3 0.0 3.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase zf-CHC2 PF01807.20 CEG43271.1 - 0.044 13.6 0.2 0.05 13.4 0.2 1.1 1 0 0 1 1 1 0 CHC2 zinc finger Stc1 PF12898.7 CEG43271.1 - 0.11 13.1 4.8 0.13 12.8 4.8 1.1 1 0 0 1 1 1 0 Stc1 domain Aa_trans PF01490.18 CEG43272.1 - 1.8e-22 79.7 0.4 2.9e-22 79.0 0.4 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein MscS_TM PF12794.7 CEG43272.1 - 0.056 12.3 2.6 4.3 6.1 0.3 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Acyl_transf_3 PF01757.22 CEG43272.1 - 0.094 11.8 8.7 0.53 9.3 2.6 2.3 2 1 0 2 2 2 0 Acyltransferase family Abhydrolase_6 PF12697.7 CEG43273.1 - 0.025 15.2 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CEG43273.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 CEG43273.1 - 0.13 11.4 0.1 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase BAG6 PF12057.8 CEG43275.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 BCL2-associated athanogene 6 YodL PF14191.6 CEG43275.1 - 0.024 15.5 0.7 1.3 9.9 0.0 3.1 3 0 0 3 3 3 0 YodL-like Pex19 PF04614.12 CEG43275.1 - 0.032 14.0 0.5 0.048 13.4 0.5 1.3 1 0 0 1 1 1 0 Pex19 protein family MRP-L27 PF09809.9 CEG43277.1 - 4.1e-16 58.8 0.2 4.8e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 GBP PF02263.19 CEG43278.1 - 1.9e-63 214.1 0.2 4.5e-63 212.9 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CEG43278.1 - 1.1e-20 74.3 24.4 1.8e-19 70.3 24.3 2.3 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 CEG43278.1 - 0.067 13.3 0.1 0.9 9.6 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEG43278.1 - 4 7.5 0.0 4 7.5 0.0 2.9 3 1 0 3 3 3 0 Dynamin family Tankyrase_bdg_C PF15327.6 CEG43278.1 - 6.2 7.2 7.4 10 6.6 0.0 2.3 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain DUF155 PF02582.14 CEG43279.1 - 3.3e-27 95.7 0.2 5.5e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LRR_4 PF12799.7 CEG43284.1 - 1.8e-09 37.7 14.1 0.012 16.0 0.1 6.5 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG43284.1 - 2e-07 30.5 12.6 0.027 14.5 0.0 8.0 9 0 0 9 9 9 3 Leucine Rich repeat DHHC PF01529.20 CEG43284.1 - 0.053 13.6 1.8 0.078 13.1 0.3 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Recep_L_domain PF01030.24 CEG43284.1 - 0.092 12.9 1.8 10 6.3 0.0 3.6 1 1 3 4 4 4 0 Receptor L domain F-box PF00646.33 CEG43284.1 - 0.17 11.8 1.7 0.3 11.0 0.2 2.2 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 CEG43284.1 - 1 9.1 10.8 3.8 7.4 1.3 4.9 4 2 0 4 4 4 0 Leucine rich repeat UCH PF00443.29 CEG43285.1 - 3.5e-38 131.6 0.0 1.6e-37 129.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG43285.1 - 2.9e-16 60.0 7.4 1.3e-09 38.1 0.2 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2464 PF10240.9 CEG43285.1 - 6.3e-10 39.1 0.0 0.00014 21.5 0.0 3.9 4 1 0 4 4 4 3 Multivesicular body subunit 12 Laminin_G_3 PF13385.6 CEG43287.1 - 1e-10 41.9 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-RanBP PF00641.18 CEG43287.1 - 2.1e-05 23.7 5.4 5.4e-05 22.4 5.4 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HrpB2 PF09487.10 CEG43287.1 - 0.17 12.4 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Methyltr_RsmB-F PF01189.17 CEG43288.1 - 4.1e-18 65.8 0.0 2.3e-17 63.3 0.0 2.1 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Dus PF01207.17 CEG43289.1 - 1.3e-38 132.9 0.0 2e-22 79.7 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CEG43289.1 - 2.5e-09 36.8 9.2 0.00046 20.0 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG43289.1 - 2e-08 33.8 12.9 3e-06 26.9 0.3 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEG43289.1 - 8.8e-06 25.6 10.7 0.015 15.4 1.6 2.9 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 CEG43289.1 - 0.00056 20.3 3.2 0.27 11.8 0.2 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG43289.1 - 6.6 7.5 13.5 5.4 7.8 3.2 2.9 2 1 1 3 3 3 0 Torus domain SAM_PNT PF02198.16 CEG43290.1 - 0.048 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Oxidored_FMN PF00724.20 CEG43293.1 - 3.8e-54 184.2 0.6 6.8e-51 173.5 0.2 3.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family HLH PF00010.26 CEG43294.1 - 1.9e-08 34.1 2.2 4.2e-08 33.0 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CEG43294.1 - 0.00024 21.1 0.1 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CEG43294.1 - 0.099 12.9 0.0 0.28 11.5 0.0 1.7 2 0 0 2 2 2 0 PAS fold DUF4337 PF14235.6 CEG43294.1 - 1.4 9.0 4.7 1.9 8.5 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2203 PF09969.9 CEG43294.1 - 2.8 8.7 5.0 1.2 9.9 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DENN PF02141.21 CEG43295.1 - 3.3e-30 105.4 2.4 2e-29 102.9 0.2 2.9 3 0 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.18 CEG43295.1 - 4.8e-08 33.6 0.1 1.5e-07 32.1 0.1 1.9 1 0 0 1 1 1 1 uDENN domain PDZ_6 PF17820.1 CEG43295.1 - 0.0055 16.5 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain SPA PF08616.10 CEG43295.1 - 0.011 15.7 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis HTH_8 PF02954.19 CEG43295.1 - 0.029 14.2 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF3682 PF12446.8 CEG43295.1 - 0.14 12.6 3.9 0.49 10.9 3.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Transketolase_C PF02780.20 CEG43296.1 - 5.1e-34 116.8 0.0 8e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CEG43296.1 - 6.5e-34 117.1 0.0 1.4e-20 73.7 0.0 2.4 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 CEG43296.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 CEG43297.1 - 2.2e-81 272.7 0.1 3e-81 272.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEG43297.1 - 5.6e-20 70.9 0.5 1.3e-19 69.8 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEG43297.1 - 0.00045 20.0 1.3 0.13 12.1 0.2 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like E3_binding PF02817.17 CEG43297.1 - 0.00092 19.5 0.1 0.0028 17.9 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain HlyD_D23 PF16576.5 CEG43297.1 - 0.027 13.7 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RCC1 PF00415.18 CEG43298.1 - 1.2e-92 304.4 20.6 1.4e-16 60.8 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG43298.1 - 3.4e-43 144.6 40.8 4.9e-09 35.8 1.0 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CEG43298.1 - 1.5e-17 63.8 0.1 4.7e-17 62.2 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CEG43298.1 - 2.7e-05 24.2 1.6 5.2e-05 23.3 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF4213 PF13938.6 CEG43298.1 - 7.3e-05 22.9 2.1 4.9 7.5 0.0 5.0 4 1 0 4 4 4 1 Putative heavy-metal chelation NMD3 PF04981.13 CEG43301.1 - 4.1e-78 262.2 6.6 6.4e-78 261.6 6.6 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.8 CEG43301.1 - 1.7 8.6 4.4 2.1 8.3 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) U3_assoc_6 PF08640.11 CEG43302.1 - 1.9e-26 91.9 3.5 1.9e-26 91.9 3.5 2.7 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CEG43302.1 - 1.7e-06 28.3 2.8 0.064 14.1 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CEG43302.1 - 0.00072 18.8 7.6 0.02 14.1 0.1 4.3 2 2 1 3 3 3 1 NRDE-2, necessary for RNA interference Suf PF05843.14 CEG43302.1 - 0.023 14.7 0.7 0.59 10.1 0.0 3.3 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) DUF2594 PF10769.9 CEG43302.1 - 0.088 12.9 1.1 0.22 11.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) FBD PF08387.10 CEG43302.1 - 0.12 12.3 0.1 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 FBD Tom37 PF10568.9 CEG43303.1 - 4.1e-20 72.3 0.1 8.2e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CEG43303.1 - 3.9e-14 53.2 0.3 1.3e-13 51.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CEG43303.1 - 4.6e-09 35.9 0.0 2.8e-08 33.4 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEG43303.1 - 2.2e-05 24.4 0.0 6.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Myb_DNA-binding PF00249.31 CEG43304.1 - 2.7e-36 123.5 11.2 9.8e-15 54.5 0.9 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG43304.1 - 3.1e-32 110.6 3.2 1.8e-15 56.9 0.1 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEG43304.1 - 0.00047 20.2 0.0 0.33 11.0 0.0 2.9 2 0 0 2 2 2 2 SLIDE Rap1_C PF11626.8 CEG43304.1 - 0.16 12.1 3.4 2 8.6 1.7 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Telomere_reg-2 PF10193.9 CEG43305.1 - 1.1e-24 87.0 3.1 1.8e-24 86.3 1.5 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Argos PF11581.8 CEG43306.1 - 0.026 14.5 0.4 0.06 13.4 0.4 1.5 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Hydrolase_4 PF12146.8 CEG43306.1 - 0.051 12.8 0.1 0.09 12.0 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG43306.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 CEG43306.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CEG43306.1 - 0.13 11.9 0.1 0.38 10.4 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein cNMP_binding PF00027.29 CEG43307.1 - 7.2e-13 48.4 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CEG43307.1 - 1e-11 44.6 12.9 1.6e-11 43.9 12.9 1.3 1 0 0 1 1 1 1 Ion transport protein CCDC53 PF10152.9 CEG43307.1 - 0.48 10.8 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex LapA_dom PF06305.11 CEG43307.1 - 0.8 9.6 2.4 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SNF2_N PF00176.23 CEG43308.1 - 2.9e-57 194.0 0.8 4.7e-57 193.3 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG43308.1 - 3.8e-20 72.3 1.5 3.9e-19 69.0 0.0 3.1 3 2 2 5 5 5 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEG43308.1 - 2.5e-07 30.2 0.3 0.0027 16.9 0.1 3.1 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 RYDR_ITPR PF01365.21 CEG43308.1 - 0.017 14.5 0.4 0.036 13.5 0.4 1.6 1 0 0 1 1 1 0 RIH domain Hrs_helical PF12210.8 CEG43308.1 - 0.029 14.9 2.4 0.24 12.0 0.3 2.8 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CP_ATPgrasp_2 PF14403.6 CEG43308.1 - 0.057 12.3 0.4 0.09 11.7 0.4 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 TPPII_N PF12583.8 CEG43308.1 - 0.32 11.6 2.5 0.43 11.2 0.2 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal NPP1 PF05630.11 CEG43309.1 - 2.3e-46 158.4 0.3 2.7e-46 158.2 0.3 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF3458_C PF17432.2 CEG43309.1 - 0.18 11.2 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats NPP1 PF05630.11 CEG43310.1 - 4.9e-51 173.6 0.1 5.7e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) KORA PF16509.5 CEG43312.1 - 0.073 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor fn3 PF00041.21 CEG43315.1 - 2.3e-11 43.9 10.9 0.069 13.5 0.1 8.7 9 0 0 9 9 9 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG43315.1 - 0.00033 21.2 22.1 0.47 11.1 0.0 7.6 9 0 0 9 9 9 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CEG43315.1 - 0.16 12.4 0.0 0.16 12.4 0.0 6.8 7 1 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) Mid1 PF12929.7 CEG43315.1 - 0.16 11.1 8.2 0.79 8.8 0.3 4.6 4 1 1 5 5 5 0 Stretch-activated Ca2+-permeable channel component Pkinase PF00069.25 CEG43316.1 - 1e-69 234.9 0.1 1.4e-69 234.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43316.1 - 3.4e-39 134.7 0.0 5e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG43316.1 - 4.6e-10 39.3 0.0 5.1e-09 35.9 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG43316.1 - 3.3e-06 26.1 0.0 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG43316.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG43316.1 - 0.0059 16.0 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG43316.1 - 0.0074 15.9 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEG43316.1 - 0.051 12.5 0.2 0.1 11.5 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEG43316.1 - 0.053 13.1 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HeLo PF14479.6 CEG43316.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Prion-inhibition and propagation Pkinase_C PF00433.24 CEG43316.1 - 0.14 12.9 0.4 0.14 12.9 0.4 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain CAP PF00188.26 CEG43317.1 - 6.5e-13 49.6 2.1 8.3e-13 49.3 2.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2096 PF09869.9 CEG43319.1 - 0.008 16.3 3.5 0.025 14.6 1.3 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2096) FOXP-CC PF16159.5 CEG43319.1 - 0.22 12.1 2.0 0.52 11.0 0.7 2.4 3 0 0 3 3 3 0 FOXP coiled-coil domain CSD PF00313.22 CEG43320.1 - 4.9e-20 71.1 18.2 1.6e-06 27.8 0.1 8.6 9 1 0 9 9 9 3 'Cold-shock' DNA-binding domain R3H PF01424.22 CEG43320.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain ThiS PF02597.20 CEG43320.1 - 0.14 12.8 0.2 4.3 8.1 0.0 3.3 3 0 0 3 3 3 0 ThiS family S1-like PF14444.6 CEG43320.1 - 4.2 7.4 11.5 83 3.2 0.2 6.0 7 0 0 7 7 7 0 S1-like Acyl-CoA_ox_N PF14749.6 CEG43321.1 - 6.7e-29 101.0 0.0 9.3e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEG43321.1 - 4.6e-14 52.4 0.0 7.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEG43321.1 - 0.01 16.5 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain ACOX PF01756.19 CEG43322.1 - 6e-52 175.8 0.1 1e-51 175.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 CEG43322.1 - 0.00091 19.5 0.7 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ATP_bind_3 PF01171.20 CEG43323.1 - 3.3e-36 124.8 0.0 5.7e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 CEG43323.1 - 1.3e-22 80.8 0.5 2.3e-22 80.0 0.5 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) QueC PF06508.13 CEG43323.1 - 3.1e-06 26.8 0.0 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 CEG43323.1 - 2.7e-05 24.3 0.1 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 CEG43323.1 - 0.00022 20.1 0.0 0.00035 19.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CEG43323.1 - 0.00027 20.7 0.0 0.00069 19.4 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase NAD_synthase PF02540.17 CEG43323.1 - 0.00048 19.3 0.0 0.00099 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD synthase ThiI PF02568.14 CEG43323.1 - 0.0011 18.6 0.0 0.0049 16.5 0.0 1.9 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) RNA_pol_Rpb5_C PF01191.19 CEG43324.1 - 1e-31 108.6 0.1 1.8e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CEG43324.1 - 4.1e-29 101.0 0.0 6.6e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain BamHI PF02923.15 CEG43324.1 - 0.0099 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease BamHI Mrr_cat PF04471.12 CEG43324.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease SAM_1 PF00536.30 CEG43325.1 - 9.1e-13 48.5 0.2 2.5e-12 47.0 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG43325.1 - 1.5e-12 47.5 0.1 5.2e-12 45.7 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) dCMP_cyt_deam_1 PF00383.23 CEG43325.1 - 1.5e-05 24.8 0.9 4.6e-05 23.2 0.9 1.9 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region EF-hand_6 PF13405.6 CEG43325.1 - 7.4e-05 22.4 0.6 0.00066 19.4 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEG43325.1 - 0.00023 20.5 0.1 0.0018 17.7 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CEG43325.1 - 0.00054 20.4 0.8 0.056 13.9 0.0 4.3 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG43325.1 - 0.007 15.8 0.4 0.022 14.2 0.4 2.0 1 0 0 1 1 1 1 EF hand SAM_PNT PF02198.16 CEG43325.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Agenet PF05641.12 CEG43325.1 - 0.13 12.7 0.0 27 5.3 0.0 2.9 2 0 0 2 2 2 0 Agenet domain Chromo PF00385.24 CEG43328.1 - 2.7e-11 43.2 0.1 3.7e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEG43328.1 - 0.048 13.8 2.3 0.11 12.7 2.3 1.5 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 IF4E PF01652.18 CEG43330.1 - 2.3e-58 196.5 0.1 3.5e-58 195.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SBE2 PF17076.5 CEG43330.1 - 0.017 13.4 4.3 0.022 13.0 4.3 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation DUF86 PF01934.17 CEG43330.1 - 0.12 12.3 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF86 Presenilin PF01080.17 CEG43330.1 - 2.5 6.8 4.7 3.6 6.2 4.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2570 PF10828.8 CEG43331.1 - 0.0068 16.2 3.1 0.0068 16.2 3.1 4.9 3 2 0 4 4 4 1 Protein of unknown function (DUF2570) TMF_TATA_bd PF12325.8 CEG43331.1 - 0.0074 16.5 1.1 0.0074 16.5 1.1 8.2 7 2 0 7 7 7 3 TATA element modulatory factor 1 TATA binding MSC PF09402.10 CEG43333.1 - 2.8e-16 59.9 14.4 2.2e-12 47.1 1.2 3.2 1 1 1 3 3 3 2 Man1-Src1p-C-terminal domain Ferlin_C PF16165.5 CEG43333.1 - 0.0011 18.9 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 Ferlin C-terminus Wzy_C PF04932.15 CEG43333.1 - 0.036 13.7 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 O-Antigen ligase RCC1 PF00415.18 CEG43334.1 - 1e-55 186.1 11.3 1.7e-11 44.6 0.3 8.1 6 1 1 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG43334.1 - 2.6e-32 109.9 31.4 2e-06 27.4 1.8 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat eIF3_p135 PF12807.7 CEG43334.1 - 0.0002 21.5 0.0 0.00057 20.0 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Tetraspanin PF00335.20 CEG43334.1 - 0.0003 20.6 8.2 0.00056 19.7 8.2 1.5 1 0 0 1 1 1 1 Tetraspanin family PMP22_Claudin PF00822.20 CEG43334.1 - 0.052 13.4 4.6 0.12 12.2 4.6 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2118 PF09891.9 CEG43335.1 - 0.056 13.4 0.0 0.085 12.8 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF4097 PF13349.6 CEG43338.1 - 2.8e-12 46.5 6.0 5.6e-08 32.5 2.5 2.3 1 1 1 2 2 2 2 Putative adhesin tRNA_NucTransf2 PF09249.11 CEG43338.1 - 0.00059 20.1 0.0 0.074 13.3 0.0 2.7 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain DUF1874 PF08960.10 CEG43338.1 - 0.081 13.1 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) Fringe PF02434.16 CEG43339.1 - 9.8e-14 51.4 0.0 1.9e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 CEG43339.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 CEG43339.1 - 0.14 12.0 0.1 0.34 10.7 0.0 1.8 2 1 0 2 2 2 0 Galactosyltransferase Cu-oxidase_2 PF07731.14 CEG43340.1 - 1.5e-33 115.4 10.7 3.7e-27 94.7 1.0 4.1 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEG43340.1 - 9.1e-31 106.4 4.9 8.9e-30 103.1 0.3 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 CEG43340.1 - 3.7e-22 79.1 0.1 1.9e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase ThiF PF00899.21 CEG43341.1 - 3e-29 102.1 0.1 3.7e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family ArenaCapSnatch PF17296.2 CEG43341.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain 2-Hacid_dh_C PF02826.19 CEG43341.1 - 0.031 13.6 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEG43341.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding BH4 PF02180.17 CEG43341.1 - 0.18 11.6 0.4 0.4 10.5 0.4 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Peptidase_C1 PF00112.23 CEG43342.1 - 5e-58 196.8 2.6 6.4e-58 196.4 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CEG43342.1 - 0.0044 15.8 1.3 0.74 8.5 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family EF-hand_1 PF00036.32 CEG43343.1 - 7.2e-20 69.0 2.5 1.9e-05 23.9 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CEG43343.1 - 1.5e-16 60.0 5.0 3e-11 43.0 0.6 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG43343.1 - 2e-16 58.5 1.4 0.00046 19.9 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CEG43343.1 - 3.5e-16 59.4 11.5 3.5e-09 37.0 1.9 3.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG43343.1 - 1.9e-12 46.0 1.6 1.9e-05 23.9 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CEG43343.1 - 0.0012 19.1 1.2 0.27 11.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 CEG43343.1 - 0.0019 19.0 1.3 0.13 13.2 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain Mlo PF03094.15 CEG43343.1 - 0.0041 15.6 5.2 0.35 9.2 0.8 2.5 2 1 0 2 2 2 2 Mlo family p25-alpha PF05517.12 CEG43343.1 - 0.23 11.6 0.1 0.65 10.1 0.0 1.6 1 1 0 1 1 1 0 p25-alpha DUF5039 PF16442.5 CEG43344.1 - 0.067 12.7 0.0 0.077 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) DUF4122 PF13498.6 CEG43344.1 - 0.08 12.6 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) DUF1187 PF06688.11 CEG43345.1 - 0.05 14.0 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Trypsin_2 PF13365.6 CEG43346.1 - 1.5e-13 51.9 0.0 4e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG43346.1 - 0.037 13.8 4.8 0.58 9.9 4.8 2.4 1 1 0 1 1 1 0 Trypsin Peptidase_C4 PF00863.19 CEG43346.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C4 Pkinase PF00069.25 CEG43347.1 - 3.4e-52 177.4 0.0 5.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43347.1 - 2.9e-47 161.1 0.0 3.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CD34_antigen PF06365.12 CEG43347.1 - 0.029 13.9 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family Haspin_kinase PF12330.8 CEG43347.1 - 0.037 13.0 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CEG43347.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3430 PF11912.8 CEG43347.1 - 0.21 11.6 4.3 0.35 10.9 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Pkinase PF00069.25 CEG43348.1 - 8.7e-47 159.7 0.0 2e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43348.1 - 2.2e-41 141.9 0.0 8.5e-41 139.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sif PF06767.11 CEG43350.1 - 0.07 12.1 0.2 0.081 11.9 0.2 1.1 1 0 0 1 1 1 0 Sif protein Erv26 PF04148.13 CEG43353.1 - 0.023 14.5 0.2 0.024 14.5 0.2 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Sec63 PF02889.16 CEG43355.1 - 1.7e-150 499.3 0.1 7.4e-82 274.4 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEG43355.1 - 2.6e-41 141.3 0.0 1.9e-24 86.4 0.2 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CEG43355.1 - 1.3e-36 125.1 1.5 1.3e-36 125.1 1.5 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CEG43355.1 - 7.7e-19 68.3 0.0 1.4e-12 48.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEG43355.1 - 1.6e-10 41.3 0.0 1.5e-08 34.9 0.0 3.6 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEG43355.1 - 1.3e-05 25.5 0.1 0.0039 17.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG43355.1 - 0.0017 18.1 0.0 0.1 12.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEG43355.1 - 0.022 14.5 0.0 0.75 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain ADIP PF11559.8 CEG43356.1 - 1.7e-06 28.2 15.6 1.7e-06 28.2 15.6 4.4 5 0 0 5 5 5 1 Afadin- and alpha -actinin-Binding TTL PF03133.15 CEG43357.1 - 1.6e-55 188.3 0.2 2.3e-55 187.8 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CAT PF00302.18 CEG43357.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase CRAL_TRIO PF00650.20 CEG43358.1 - 7.5e-11 42.0 0.1 0.00023 20.9 0.0 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain ERp29_N PF07912.13 CEG43358.1 - 0.093 12.9 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 ERp29, N-terminal domain TraD_N PF12615.8 CEG43360.1 - 0.0015 19.2 0.1 0.0019 18.9 0.1 1.1 1 0 0 1 1 1 1 F sex factor protein N terminal PGG PF13962.6 CEG43360.1 - 0.031 14.1 0.2 0.049 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function HTH_Tnp_Tc3_2 PF01498.18 CEG43361.1 - 1.7e-05 25.0 1.3 2.8e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 Transposase Sigma70_r4 PF04545.16 CEG43361.1 - 0.00062 19.2 0.2 0.59 9.7 0.0 2.7 3 0 0 3 3 3 2 Sigma-70, region 4 HTH_AsnC-type PF13404.6 CEG43361.1 - 0.0035 17.1 1.0 0.027 14.3 0.2 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_30 PF13556.6 CEG43361.1 - 0.0048 16.7 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 CEG43361.1 - 0.005 16.4 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.6 CEG43361.1 - 0.015 15.0 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_22 PF13309.6 CEG43361.1 - 0.017 15.2 0.4 0.23 11.6 0.0 2.7 3 0 0 3 3 3 0 HTH domain HTH_28 PF13518.6 CEG43361.1 - 0.019 15.1 0.1 7.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 CEG43361.1 - 0.019 14.9 0.7 0.045 13.7 0.2 1.9 2 0 0 2 2 2 0 HTH domain HTH_8 PF02954.19 CEG43361.1 - 0.08 12.7 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_10 PF04967.12 CEG43361.1 - 0.088 12.6 0.2 21 5.0 0.0 3.0 3 0 0 3 3 3 0 HTH DNA binding domain HTH_IclR PF09339.10 CEG43361.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 CEG43361.1 - 0.1 12.4 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain DUF469 PF04320.14 CEG43361.1 - 0.16 12.8 0.0 0.33 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein with unknown function (DUF469) HTH_50 PF18024.1 CEG43361.1 - 0.28 10.8 1.2 0.64 9.7 1.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF724 PF05266.14 CEG43362.1 - 2.1 8.2 11.7 4.4 7.1 5.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Uds1 PF15456.6 CEG43362.1 - 2.8 8.1 11.4 0.3 11.3 4.9 2.8 2 0 0 2 2 2 0 Up-regulated During Septation SNF2_N PF00176.23 CEG43363.1 - 2.6e-13 49.4 0.0 9.2e-13 47.6 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG43363.1 - 1.3e-07 31.9 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG43363.1 - 0.00061 19.8 1.4 0.0072 16.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Glyco_tranf_2_5 PF13712.6 CEG43363.1 - 0.091 12.4 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family Pro_isomerase PF00160.21 CEG43364.1 - 6e-51 172.8 0.1 6.7e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aminotran_5 PF00266.19 CEG43365.1 - 1.1e-32 113.4 0.0 7.3e-32 110.7 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 CEG43365.1 - 1.5e-27 96.2 0.0 2.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CEG43365.1 - 1.5e-17 63.6 0.0 1.2e-16 60.7 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Pkinase PF00069.25 CEG43369.1 - 8.3e-55 186.0 0.0 1.2e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43369.1 - 1.4e-28 99.9 0.0 1.2e-26 93.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG43369.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG43369.1 - 0.0057 16.0 1.3 0.01 15.2 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG43369.1 - 0.0058 16.6 0.1 0.0099 15.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEG43369.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PB1 PF00564.24 CEG43370.1 - 2.2e-10 40.3 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain CUE PF02845.16 CEG43370.1 - 0.008 15.9 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 CUE domain ISET-FN3_linker PF16625.5 CEG43370.1 - 0.14 12.7 1.2 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO DUF4205 PF13898.6 CEG43371.1 - 0.0057 15.6 0.6 0.012 14.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) NDUFV3 PF15880.5 CEG43371.1 - 0.097 12.7 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial zf-RanBP PF00641.18 CEG43372.1 - 0.0029 16.9 2.9 0.0046 16.2 2.9 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 CEG43372.1 - 0.084 12.9 0.2 0.084 12.9 0.2 1.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Toxin_5 PF05294.13 CEG43372.1 - 4.3 7.8 7.8 0.93 10.0 3.5 1.9 2 0 0 2 2 2 0 Scorpion short toxin CH PF00307.31 CEG43374.1 - 2e-73 243.5 5.8 2.9e-18 66.0 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CEG43374.1 - 1.2e-08 34.6 0.2 0.037 13.9 0.0 4.6 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.6 CEG43374.1 - 0.0014 19.1 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Swi3 PF07962.12 CEG43375.1 - 3.4e-22 78.2 0.0 4.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SSURE PF11966.8 CEG43375.1 - 0.043 13.6 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Fibronectin-binding repeat Transferase PF02458.15 CEG43376.1 - 2.9e-37 128.4 0.0 3.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Transferase family Transferase PF02458.15 CEG43378.1 - 4.8e-41 140.8 0.0 6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Transferase family Peptidase_S80 PF07230.11 CEG43378.1 - 0.21 9.9 0.0 0.3 9.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Transferase PF02458.15 CEG43379.1 - 1.5e-36 126.0 0.0 2.5e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 Transferase family ubiquitin PF00240.23 CEG43380.1 - 0.0076 16.0 0.1 0.65 9.8 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin family DUF2407 PF10302.9 CEG43380.1 - 0.047 14.2 0.9 2.2 8.9 0.4 2.7 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain CIDR1_gamma PF18562.1 CEG43382.1 - 0.044 13.9 0.4 0.06 13.4 0.4 1.4 1 1 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma LptF_LptG PF03739.14 CEG43384.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF5049 PF16468.5 CEG43385.1 - 0.077 12.9 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) zf-ANAPC11 PF12861.7 CEG43386.1 - 0.11 12.5 0.2 0.14 12.2 0.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lzipper-MIP1 PF14389.6 CEG43388.1 - 0.00025 21.3 4.2 0.24 11.7 0.4 2.4 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Vps5 PF09325.10 CEG43388.1 - 0.14 11.7 1.0 9.6 5.7 0.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like EF-hand_6 PF13405.6 CEG43392.1 - 6.9e-06 25.6 3.5 0.013 15.4 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CEG43392.1 - 2.4e-05 23.6 3.7 0.042 13.4 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CEG43392.1 - 0.00087 19.7 4.4 0.94 10.0 0.1 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG43392.1 - 0.062 12.8 4.6 0.22 11.1 0.2 2.6 2 0 0 2 2 2 0 EF hand MaoC_dehydratas PF01575.19 CEG43393.1 - 1e-11 44.5 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 CEG43393.1 - 0.078 13.3 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Cyclin_N PF00134.23 CEG43394.1 - 1.8e-06 27.7 0.4 2.9e-06 27.1 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 CEG43395.1 - 1.3e-15 57.5 4.4 0.0013 19.5 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43395.1 - 0.0065 16.7 0.4 0.92 9.8 0.1 3.4 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2859 PF11072.8 CEG43395.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) FDF PF09532.10 CEG43398.1 - 0.15 13.0 0.0 0.19 12.6 0.0 1.1 1 0 0 1 1 1 0 FDF domain GTA_TIM PF13547.6 CEG43399.1 - 0.095 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain RVT_2 PF07727.14 CEG43400.1 - 6.3e-09 35.8 0.0 2.1e-08 34.1 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1g PF09334.11 CEG43401.1 - 3.2e-100 335.6 1.9 3.3e-99 332.3 1.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEG43401.1 - 2.9e-26 91.9 0.3 1.4e-15 56.6 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CEG43401.1 - 3e-11 43.2 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CEG43401.1 - 0.0055 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (K) peroxidase PF00141.23 CEG43402.1 - 2.5e-42 145.1 0.0 3.3e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase TIP41 PF04176.13 CEG43403.1 - 3.1e-58 196.0 0.3 4.2e-58 195.6 0.3 1.2 1 0 0 1 1 1 1 TIP41-like family CBFD_NFYB_HMF PF00808.23 CEG43405.1 - 0.00089 19.5 0.1 0.00089 19.5 0.1 1.8 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SIKE PF05769.11 CEG43405.1 - 0.009 16.0 6.0 0.012 15.6 6.0 1.2 1 0 0 1 1 1 1 SIKE family Hema_stalk PF08720.10 CEG43405.1 - 0.051 13.3 2.0 0.78 9.4 0.6 2.0 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk Rrf2 PF02082.20 CEG43405.1 - 0.069 13.5 2.5 2 8.8 0.1 2.2 1 1 1 2 2 2 0 Transcriptional regulator Exo_endo_phos PF03372.23 CEG43406.1 - 9.7e-11 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.6 CEG43413.1 - 0.076 12.8 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like Cse1 PF08506.10 CEG43415.1 - 8.7e-124 413.1 1.8 1.4e-123 412.4 1.8 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CEG43415.1 - 1.9e-109 366.1 0.0 3.9e-109 365.1 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CEG43415.1 - 3.6e-16 58.8 0.7 8.8e-16 57.6 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CEG43415.1 - 0.0025 18.2 0.0 4.1 7.9 0.0 3.1 2 0 0 2 2 2 2 HEAT repeats Xpo1 PF08389.12 CEG43415.1 - 0.024 14.7 2.2 0.55 10.3 0.1 4.1 4 1 0 4 4 4 0 Exportin 1-like protein HEAT PF02985.22 CEG43415.1 - 0.07 13.4 0.8 6.2 7.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat GATase_6 PF13522.6 CEG43416.1 - 2.8e-16 59.9 0.0 1.3e-15 57.8 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEG43416.1 - 8.4e-16 58.0 0.0 4.5e-15 55.6 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CEG43416.1 - 5.6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CEG43416.1 - 2.6e-07 29.8 0.0 4.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PA PF02225.22 CEG43416.1 - 0.057 13.4 0.5 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 PA domain Nup96 PF12110.8 CEG43421.1 - 6.8e-70 235.5 3.6 1.3e-69 234.6 3.6 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CEG43421.1 - 1e-39 136.1 0.0 1.8e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Rad60-SLD PF11976.8 CEG43421.1 - 0.00098 18.9 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEG43421.1 - 0.0023 17.6 0.1 0.0051 16.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CEG43421.1 - 0.0039 17.3 0.1 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like N1221 PF07923.13 CEG43421.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 N1221-like protein Methyltransf_15 PF09445.10 CEG43422.1 - 1.3e-16 60.6 0.1 2.7e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CEG43422.1 - 3.6e-05 23.5 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 CEG43422.1 - 0.023 14.3 2.0 0.05 13.2 0.0 2.5 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F SAM_MT PF04445.13 CEG43422.1 - 0.029 13.8 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase BCL9 PF11502.8 CEG43422.1 - 0.65 9.9 11.7 2.5 8.0 11.7 2.0 1 0 0 1 1 1 0 B-cell lymphoma 9 protein RVT_1 PF00078.27 CEG43427.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEG43429.1 - 6e-20 71.6 0.1 1.1e-19 70.7 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG43429.1 - 6.5e-05 22.7 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CEG43429.1 - 7.9e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Guanylate_cyc PF00211.20 CEG43431.1 - 4.3e-90 300.2 8.6 1.7e-51 174.4 1.6 3.5 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 CEG43431.1 - 5e-63 213.2 22.0 5e-63 213.2 22.0 3.6 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG43431.1 - 4.1e-22 77.7 3.0 1.1e-21 76.3 3.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG43431.1 - 2.3e-06 28.0 0.0 0.0026 18.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG43431.1 - 2.4e-06 27.5 0.0 4.3e-05 23.5 0.0 2.9 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG43431.1 - 0.00014 21.4 0.1 0.0013 18.3 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase HNOBA PF07701.14 CEG43431.1 - 0.022 14.2 0.9 2.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Heme NO binding associated Hydrolase_3 PF08282.12 CEG43431.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 CEG43431.1 - 0.1 13.0 4.3 0.33 11.4 2.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ank_2 PF12796.7 CEG43432.1 - 2.3e-36 124.2 19.4 1.7e-09 38.1 0.0 6.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG43432.1 - 4.6e-31 106.8 7.0 9.7e-05 22.8 0.0 9.1 6 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG43432.1 - 1.1e-21 76.6 12.3 0.041 14.2 0.0 12.1 2 1 11 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG43432.1 - 2.9e-15 54.8 1.4 3.1 8.6 0.0 12.3 12 2 2 14 14 14 2 Ankyrin repeat DUF5049 PF16468.5 CEG43432.1 - 2.7e-09 36.8 4.1 0.3 11.0 0.0 8.0 6 3 4 10 10 10 2 Domain of unknown function (DUF5049) Ank PF00023.30 CEG43432.1 - 4.9e-06 26.7 2.0 45 4.7 0.0 8.6 3 2 2 5 5 5 0 Ankyrin repeat Tom37 PF10568.9 CEG43432.1 - 0.0086 16.4 0.1 44 4.4 0.0 4.6 2 2 2 4 4 4 0 Outer mitochondrial membrane transport complex protein DUF1843 PF08898.10 CEG43432.1 - 0.7 10.4 5.2 54 4.4 0.0 5.5 9 0 0 9 9 9 0 Domain of unknown function (DUF1843) ABA_GPCR PF12430.8 CEG43433.1 - 1.7e-33 115.9 7.1 1.7e-33 115.9 7.1 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CEG43433.1 - 1.1e-22 79.9 0.0 2.8e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal zf-SNAP50_C PF12251.8 CEG43434.1 - 2.2e-48 164.6 1.0 4.3e-48 163.6 1.0 1.5 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal CEBP_ZZ PF16366.5 CEG43434.1 - 0.18 12.1 2.1 0.39 11.0 2.1 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AAA_23 PF13476.6 CEG43434.1 - 0.43 11.1 6.9 1.1 9.8 6.9 1.6 1 0 0 1 1 1 0 AAA domain zf-Dof PF02701.15 CEG43434.1 - 1.4 9.1 3.9 2.9 8.1 3.9 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger Thiolase_N PF00108.23 CEG43435.1 - 6.2e-81 271.6 4.2 9.6e-81 271.0 4.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEG43435.1 - 4.2e-47 158.8 0.3 8e-47 157.9 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEG43435.1 - 0.021 14.4 2.9 0.035 13.7 1.6 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain HTH_10 PF04967.12 CEG43435.1 - 0.053 13.3 0.1 20 5.1 0.0 3.2 2 1 1 3 3 3 0 HTH DNA binding domain ACP_syn_III_C PF08541.10 CEG43435.1 - 0.056 13.6 0.9 0.27 11.4 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF5613 PF18467.1 CEG43436.1 - 0.92 10.0 5.0 0.19 12.2 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) Ion_trans PF00520.31 CEG43438.1 - 3.8e-27 95.1 34.9 1.4e-14 53.9 7.0 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 CEG43438.1 - 2.9e-15 56.0 26.6 9.6e-09 35.1 2.5 3.4 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 CEG43438.1 - 0.13 12.1 5.1 4.1 7.2 2.4 2.9 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain GMC_oxred_N PF00732.19 CEG43440.1 - 2.6e-48 164.9 0.0 3.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEG43440.1 - 1.6e-25 90.3 0.0 2.9e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CEG43440.1 - 0.00065 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG43440.1 - 0.00082 19.1 1.5 0.0017 18.0 0.5 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEG43440.1 - 0.0083 14.9 0.3 0.052 12.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CEG43440.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CEG43440.1 - 0.027 13.7 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CEG43440.1 - 0.034 13.2 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CEG43440.1 - 0.093 11.9 0.1 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG43440.1 - 0.096 11.9 0.2 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M24 PF00557.24 CEG43441.1 - 2.7e-50 171.0 0.1 8e-50 169.4 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 CEG43441.1 - 6.1e-26 90.6 0.1 4.2e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Med13_C PF06333.12 CEG43442.1 - 2.3e-17 63.3 3.5 1.5e-09 37.6 0.0 3.5 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 CEG43442.1 - 1.4e-11 44.4 0.4 3.2e-11 43.2 0.4 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal GAS PF13851.6 CEG43442.1 - 0.0016 17.8 4.9 0.0016 17.8 4.9 3.6 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3246 PF11596.8 CEG43442.1 - 0.1 12.0 3.8 0.18 11.2 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) HALZ PF02183.18 CEG43442.1 - 1 9.6 7.6 6.1 7.2 0.6 3.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper MbeD_MobD PF04899.12 CEG43442.1 - 9.1 6.5 13.3 7.1 6.8 2.8 3.6 2 1 0 2 2 2 0 MbeD/MobD like RWP-RK PF02042.15 CEG43443.1 - 1.9e-16 59.8 0.1 3.6e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain V-SNARE_C PF12352.8 CEG43444.1 - 9.7e-07 29.0 1.0 1.7e-06 28.2 1.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CEG43444.1 - 3.4e-06 27.3 0.3 3.4e-06 27.3 0.3 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus TraG_N PF07916.11 CEG43444.1 - 0.0014 17.5 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 TraG-like protein, N-terminal region V_ATPase_I PF01496.19 CEG43444.1 - 0.019 12.9 0.6 0.023 12.6 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.6 CEG43444.1 - 0.086 12.2 4.4 0.13 11.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) PMP1_2 PF08114.11 CEG43444.1 - 0.1 12.3 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 ATPase proteolipid family DUF2371 PF10177.9 CEG43444.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) CorA PF01544.18 CEG43444.1 - 0.12 11.7 1.4 0.2 10.9 1.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 CEG43444.1 - 0.43 8.5 4.6 0.44 8.5 2.1 1.9 1 1 2 3 3 3 0 Prominin Tubulin_C PF03953.17 CEG43445.1 - 3.3e-23 82.2 0.0 4.5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain GH131_N PF18271.1 CEG43446.1 - 8.4e-18 65.0 0.1 1.1e-17 64.6 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG43446.1 - 0.027 14.3 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide lyase GH131_N PF18271.1 CEG43447.1 - 7.3e-41 140.5 0.0 8.8e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain OpgC_C PF10129.9 CEG43447.1 - 0.19 10.6 0.2 0.3 9.9 0.2 1.2 1 0 0 1 1 1 0 OpgC protein RVT_2 PF07727.14 CEG43450.1 - 0.058 13.0 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ABC2_membrane PF01061.24 CEG43451.1 - 1.6e-68 230.2 62.0 2e-40 138.5 19.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CEG43451.1 - 1.1e-34 119.9 0.0 6.7e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 CEG43451.1 - 6.9e-07 29.3 0.0 0.00057 19.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 CEG43451.1 - 1.1e-06 28.0 14.0 1.1e-06 28.0 14.0 3.2 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.6 CEG43451.1 - 5.9e-06 25.9 0.3 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG43451.1 - 8.4e-06 26.1 0.0 0.069 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEG43451.1 - 1.9e-05 24.3 0.5 0.18 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CEG43451.1 - 4.4e-05 24.1 1.2 0.078 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CEG43451.1 - 0.00012 22.0 0.3 3.3 7.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CEG43451.1 - 0.00034 20.7 0.2 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CEG43451.1 - 0.00034 21.2 0.1 0.95 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG43451.1 - 0.00044 20.7 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEG43451.1 - 0.00082 19.6 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEG43451.1 - 0.0031 17.2 4.2 0.59 9.8 0.5 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEG43451.1 - 0.0053 17.2 0.6 5.4 7.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CEG43451.1 - 0.008 16.2 1.3 0.3 11.1 0.2 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CEG43451.1 - 0.02 14.2 1.3 3.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 CEG43451.1 - 0.044 13.9 2.6 1.6 8.8 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 CEG43451.1 - 0.049 12.6 0.6 3.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CEG43451.1 - 0.055 13.9 0.1 14 6.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.6 CEG43451.1 - 0.079 13.2 1.1 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CEG43451.1 - 0.1 11.9 0.1 16 4.7 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ploopntkinase3 PF18751.1 CEG43451.1 - 0.14 12.1 1.1 13 5.7 0.2 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 CEG43451.1 - 0.19 11.3 2.5 4.3 6.9 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEG43451.1 - 0.31 11.0 4.9 4.4 7.2 0.9 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CEG43451.1 - 0.41 10.5 2.1 11 5.9 0.0 2.7 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 CEG43451.1 - 0.56 9.9 1.8 18 4.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEG43451.1 - 1.2 9.4 3.2 13 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Chromo PF00385.24 CEG43453.1 - 2e-05 24.4 2.5 3.6e-05 23.6 2.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 CEG43454.1 - 4.6e-43 147.0 0.9 1.3e-42 145.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG43454.1 - 9.6e-21 74.2 0.3 5.1e-20 71.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 CEG43454.1 - 4.7e-06 26.4 2.6 8.7e-06 25.5 2.6 1.5 1 0 0 1 1 1 1 HIT zinc finger ResIII PF04851.15 CEG43454.1 - 0.00012 22.1 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 CEG43454.1 - 0.00064 18.6 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer UMPH-1 PF05822.12 CEG43454.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) AAA_22 PF13401.6 CEG43454.1 - 0.012 15.8 0.2 0.14 12.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CEG43454.1 - 0.032 14.6 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PH_17 PF18012.1 CEG43454.1 - 0.12 12.1 0.6 0.29 10.9 0.6 1.5 1 0 0 1 1 1 0 PH domain Lipase_3 PF01764.25 CEG43455.1 - 1.1e-30 106.4 0.0 2.5e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CEG43455.1 - 8.8e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 CEG43455.1 - 0.00054 19.6 0.1 0.0048 16.5 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) COX6A PF02046.15 CEG43455.1 - 0.0027 18.2 0.3 0.0065 16.9 0.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Abhydrolase_6 PF12697.7 CEG43455.1 - 0.034 14.8 0.0 0.085 13.4 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 CEG43455.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Phospho_p8 PF10195.9 CEG43456.1 - 0.013 16.0 2.1 0.031 14.8 2.1 1.7 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 ZZ PF00569.17 CEG43458.1 - 5.5e-09 35.7 3.0 9.7e-09 34.9 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 CEG43458.1 - 0.069 13.5 9.5 0.13 12.6 9.5 1.4 1 0 0 1 1 1 0 C1 domain AAA_13 PF13166.6 CEG43458.1 - 2.5 6.6 19.7 1.5 7.3 7.1 2.2 1 1 0 2 2 2 0 AAA domain Striatin PF08232.12 CEG43458.1 - 5.3 7.6 25.9 1.2 9.8 12.8 3.1 1 1 2 3 3 3 0 Striatin family DUF16 PF01519.16 CEG43458.1 - 9.1 6.8 11.7 5.8 7.5 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 GARS_A PF01071.19 CEG43459.1 - 2.8e-80 268.7 0.1 4.7e-80 268.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CEG43459.1 - 4.4e-32 110.7 0.4 5.1e-31 107.3 0.1 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CEG43459.1 - 1.2e-30 106.7 0.0 2.8e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Formyl_trans_N PF00551.19 CEG43459.1 - 3.7e-26 92.0 0.0 3e-23 82.5 0.0 2.4 1 1 1 2 2 2 2 Formyl transferase GARS_C PF02843.16 CEG43459.1 - 7.4e-21 74.2 0.2 2.9e-20 72.3 0.2 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CEG43459.1 - 7.6e-15 55.3 9.1 1.8e-14 54.2 1.8 3.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain AICARFT_IMPCHas PF01808.18 CEG43459.1 - 5.3e-07 29.4 0.2 3e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme ATP-grasp_3 PF02655.14 CEG43459.1 - 7.2e-07 29.4 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CEG43459.1 - 3.3e-05 23.5 0.0 6.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CEG43459.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 CEG43459.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 CEG43459.1 - 0.13 11.5 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_T_C PF08669.11 CEG43459.1 - 0.15 12.0 0.1 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain EGF_2 PF07974.13 CEG43460.1 - 3e-16 59.5 100.9 1.4e-06 28.6 9.4 9.4 10 0 0 10 10 10 8 EGF-like domain EGF PF00008.27 CEG43460.1 - 9.7e-07 29.0 72.8 0.0053 17.0 1.5 9.3 9 0 0 9 9 9 6 EGF-like domain hEGF PF12661.7 CEG43460.1 - 0.017 15.7 3.3 0.017 15.7 3.3 9.6 9 0 0 9 9 9 0 Human growth factor-like EGF Aminotran_1_2 PF00155.21 CEG43461.1 - 1.1e-62 212.3 0.0 1.7e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PDT PF00800.18 CEG43461.1 - 5.5e-56 189.3 0.0 1.1e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydratase PDH PF02153.17 CEG43461.1 - 6.4e-16 58.1 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CEG43461.1 - 9.7e-08 32.5 0.0 3.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CEG43461.1 - 0.007 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DegT_DnrJ_EryC1 PF01041.17 CEG43461.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TPH PF13868.6 CEG43463.1 - 6.2e-26 90.7 127.1 6.2e-26 90.7 127.1 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Ion_trans PF00520.31 CEG43464.1 - 4.1e-44 150.6 25.7 1.1e-23 83.8 7.8 2.8 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 CEG43464.1 - 3.1e-24 84.7 27.6 5.7e-15 55.0 2.4 3.7 4 0 0 4 4 4 2 Ion channel DUF3389 PF11869.8 CEG43464.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) IRK PF01007.20 CEG43464.1 - 0.4 10.5 12.1 0.74 9.6 0.1 4.4 3 1 0 4 4 4 0 Inward rectifier potassium channel transmembrane domain MFS_1 PF07690.16 CEG43467.1 - 1.2e-05 24.4 42.7 0.0045 15.9 0.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Nfu_N PF08712.11 CEG43471.1 - 3.5e-30 103.9 0.1 7.9e-30 102.8 0.1 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CEG43471.1 - 6.3e-25 87.1 0.0 1.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain SMP_LBD PF17047.5 CEG43472.1 - 6.8e-14 51.7 0.2 1.5e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain Promethin PF16015.5 CEG43472.1 - 0.079 12.9 1.6 0.17 11.8 1.6 1.5 1 0 0 1 1 1 0 Promethin PH PF00169.29 CEG43472.1 - 0.086 13.4 0.2 0.23 12.0 0.2 1.8 1 0 0 1 1 1 0 PH domain HOOK PF05622.12 CEG43473.1 - 3e-63 214.1 62.3 2.1e-54 184.9 45.8 3.1 2 1 0 2 2 2 2 HOOK protein CH PF00307.31 CEG43473.1 - 3.4e-05 24.0 0.2 3.4e-05 24.0 0.2 2.8 3 0 0 3 3 3 1 Calponin homology (CH) domain TPR_MLP1_2 PF07926.12 CEG43473.1 - 0.00016 21.7 11.4 0.00016 21.7 11.4 6.1 3 3 1 4 4 4 2 TPR/MLP1/MLP2-like protein CAMSAP_CH PF11971.8 CEG43473.1 - 0.00091 19.0 0.3 0.0098 15.7 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 CEG43473.1 - 0.0045 17.1 0.4 0.034 14.3 0.0 2.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CENP-F_leu_zip PF10473.9 CEG43473.1 - 0.0064 16.5 14.1 0.0064 16.5 14.1 5.0 3 2 0 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 CEG43473.1 - 0.012 15.0 3.1 0.012 15.0 3.1 5.6 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 CEG43473.1 - 0.073 12.4 35.3 0.032 13.6 7.2 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CEG43473.1 - 0.077 13.4 61.0 0.85 10.0 6.2 4.8 2 1 2 4 4 4 0 Fez1 Pox_LP_H2 PF03356.15 CEG43473.1 - 0.13 12.1 0.4 0.44 10.4 0.1 2.0 2 0 0 2 2 2 0 Viral late protein H2 ATG16 PF08614.11 CEG43473.1 - 0.15 12.3 76.7 0.059 13.6 18.7 5.9 3 3 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF3138 PF11336.8 CEG43473.1 - 1.3 7.5 7.8 0.56 8.8 0.1 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF3138) Spc7 PF08317.11 CEG43473.1 - 2.7 6.8 65.4 0.15 10.9 10.4 4.3 3 1 1 4 4 4 0 Spc7 kinetochore protein Arm PF00514.23 CEG43474.1 - 4.7e-40 134.4 13.6 1.7e-08 34.2 0.0 5.9 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEG43474.1 - 4.8e-14 52.5 11.5 7.2e-09 35.9 0.3 4.2 1 1 4 5 5 5 4 HEAT repeats Arm_2 PF04826.13 CEG43474.1 - 3e-11 43.3 11.2 1.9e-09 37.4 5.5 3.2 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 CEG43474.1 - 4.8e-10 38.2 0.1 4.1e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 CEG43474.1 - 1.7e-05 25.2 8.1 0.47 11.0 0.0 3.9 4 1 0 4 4 4 2 HEAT-like repeat Arm_3 PF16186.5 CEG43474.1 - 4.4e-05 22.9 0.1 0.037 13.6 0.0 3.1 4 0 0 4 4 3 1 Atypical Arm repeat HEAT PF02985.22 CEG43474.1 - 6.3e-05 22.9 8.4 0.17 12.2 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat V-ATPase_H_N PF03224.14 CEG43474.1 - 8.9e-05 21.9 0.8 0.00053 19.4 0.7 2.0 1 1 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CEG43474.1 - 0.00054 20.1 2.5 0.027 14.6 0.3 3.0 1 1 1 3 3 3 1 V-ATPase subunit H Adaptin_N PF01602.20 CEG43474.1 - 0.0009 17.9 0.5 0.0046 15.6 0.1 2.1 1 1 1 2 2 2 1 Adaptin N terminal region UNC45-central PF11701.8 CEG43474.1 - 0.0065 16.4 1.7 0.48 10.4 1.0 2.5 1 1 1 2 2 2 1 Myosin-binding striated muscle assembly central Cnd1 PF12717.7 CEG43474.1 - 0.016 15.2 1.7 0.49 10.4 0.2 2.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 CEG43474.1 - 0.022 15.4 5.1 1.2 10.0 1.1 4.9 4 2 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3361 PF11841.8 CEG43474.1 - 0.065 13.2 3.4 0.099 12.6 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) CTNNBL PF08216.11 CEG43474.1 - 0.066 13.4 0.7 7.2 6.8 0.0 2.6 2 1 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Aconitase_B_N PF11791.8 CEG43474.1 - 0.083 13.0 6.9 0.45 10.6 0.1 4.1 1 1 5 6 6 6 0 Aconitate B N-terminal domain NopRA1 PF16201.5 CEG43474.1 - 0.084 12.5 0.4 2.9 7.4 0.0 2.4 1 1 1 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Questin_oxidase PF14027.6 CEG43474.1 - 0.32 10.5 2.1 2.5 7.6 0.1 2.3 1 1 1 2 2 2 0 Questin oxidase-like HOASN PF14515.6 CEG43474.1 - 6 7.3 6.4 2.1 8.8 0.7 2.8 3 2 0 3 3 3 0 Haem-oxygenase-associated N-terminal helices OCRE PF17780.1 CEG43475.1 - 0.00078 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 OCRE domain DUF357 PF04010.13 CEG43476.1 - 0.069 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF357) zf-CCHC PF00098.23 CEG43478.1 - 7.1e-40 133.3 64.9 6.4e-07 29.2 4.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 CEG43478.1 - 3e-17 62.1 63.5 0.0001 22.0 3.4 6.3 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 CEG43478.1 - 1.1e-05 25.0 40.7 0.64 9.8 2.1 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_6 PF15288.6 CEG43478.1 - 0.002 18.0 47.4 0.049 13.5 0.9 6.2 5 1 1 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 CEG43478.1 - 0.0067 16.4 44.7 0.55 10.2 0.4 6.1 3 1 3 6 6 6 6 Zinc knuckle zf-CCHC_5 PF14787.6 CEG43478.1 - 0.02 14.6 1.0 0.02 14.6 1.0 6.1 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger zinc-ribbons_6 PF07191.12 CEG43478.1 - 4.6 7.3 33.2 5.4 7.1 1.1 4.0 1 1 1 2 2 2 0 zinc-ribbons MWFE PF15879.5 CEG43479.1 - 1.6e-12 47.4 0.1 2e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit PEPCK_ATP PF01293.20 CEG43480.1 - 7.2e-209 694.2 0.2 1.9e-190 633.5 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase zf-C2H2 PF00096.26 CEG43481.1 - 4.1e-21 74.2 74.3 2.1e-05 24.7 0.9 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG43481.1 - 6.8e-16 57.6 67.7 0.01 16.6 5.4 9.5 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEG43481.1 - 3.6e-12 46.1 55.4 3.5e-05 24.0 1.6 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_11 PF16622.5 CEG43481.1 - 0.019 14.7 3.8 0.019 14.7 3.8 6.3 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 CEG43481.1 - 0.14 12.5 37.8 0.14 12.5 6.3 5.1 1 1 5 6 6 6 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 CEG43481.1 - 2.5 8.1 19.3 0.35 10.8 0.2 5.4 5 0 0 5 5 5 0 zinc-ribbon domain zf-met PF12874.7 CEG43481.1 - 5.5 7.5 38.4 1.5 9.3 0.6 7.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEG43481.1 - 5.8 7.0 52.6 0.24 11.5 1.5 7.9 7 0 0 7 7 7 0 C2H2-type zinc finger zf-trcl PF13451.6 CEG43481.1 - 7.7 6.5 26.9 0.79 9.7 0.3 4.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF667 PF05018.13 CEG43482.1 - 2.2e-27 96.0 0.1 2.7e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) zf-C3HC4 PF00097.25 CEG43482.1 - 0.035 14.0 0.8 0.085 12.7 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arf PF00025.21 CEG43483.1 - 6.8e-53 178.7 0.1 8.2e-53 178.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG43483.1 - 1.5e-14 54.3 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG43483.1 - 2.9e-14 53.0 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEG43483.1 - 5.1e-14 52.1 0.0 5.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEG43483.1 - 1.1e-11 44.5 0.1 1.4e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CEG43483.1 - 2e-11 43.7 3.1 1.2e-07 31.3 0.9 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CEG43483.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG43483.1 - 0.00013 21.6 0.0 0.0034 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CEG43483.1 - 0.0037 16.8 0.1 0.0054 16.3 0.1 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CEG43483.1 - 0.0084 15.9 0.3 0.16 11.7 0.2 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CEG43483.1 - 0.012 16.2 0.0 0.018 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEG43483.1 - 0.016 15.1 0.1 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 CEG43483.1 - 0.023 14.8 0.2 0.48 10.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 CEG43483.1 - 0.06 13.1 0.0 0.35 10.6 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CEG43483.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CEG43484.1 - 0.00097 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family PLRV_ORF5 PF01690.17 CEG43485.1 - 0.093 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PFU PF09070.11 CEG43487.1 - 4e-09 36.7 0.9 0.00023 21.4 0.0 4.7 6 0 0 6 6 6 2 PFU (PLAA family ubiquitin binding) Arylesterase PF01731.20 CEG43487.1 - 0.0033 17.6 0.0 0.48 10.6 0.0 3.1 3 0 0 3 3 3 1 Arylesterase DUF2299 PF10061.9 CEG43487.1 - 0.036 13.8 3.9 1 9.1 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2299) DUF1327 PF07041.11 CEG43487.1 - 0.11 12.5 0.1 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) SPRY PF00622.28 CEG43488.1 - 1.9e-06 28.0 0.5 1e-05 25.6 0.2 2.2 2 0 0 2 2 2 1 SPRY domain Aa_trans PF01490.18 CEG43492.1 - 6e-65 219.5 30.3 7.3e-65 219.3 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG43492.1 - 3e-06 26.5 16.4 3e-06 26.5 16.4 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family LicD PF04991.13 CEG43493.1 - 2.6e-05 24.5 0.2 0.012 15.8 0.0 2.5 2 0 0 2 2 2 2 LicD family PSK_trans_fac PF07704.11 CEG43494.1 - 0.047 14.4 0.4 0.11 13.3 0.4 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor Pox_G7 PF05503.12 CEG43494.1 - 0.079 11.9 0.4 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Poxvirus G7-like LpxB PF02684.15 CEG43495.1 - 1.8e-69 234.4 2.0 2.8e-39 135.0 0.0 2.1 2 0 0 2 2 2 2 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.19 CEG43495.1 - 0.0001 21.3 0.1 0.00023 20.1 0.1 1.6 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 CEG43495.1 - 0.022 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF354) Glyco_trans_1_4 PF13692.6 CEG43495.1 - 0.048 14.1 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 PH_13 PF16652.5 CEG43495.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain RIH_assoc PF08454.11 CEG43495.1 - 0.72 9.7 3.4 5.8 6.8 0.1 2.9 3 0 0 3 3 3 0 RyR and IP3R Homology associated NARP1 PF12569.8 CEG43496.1 - 6.5e-192 639.0 28.5 2.8e-191 637.0 27.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 CEG43496.1 - 5.1e-16 57.5 8.0 6.7e-05 22.8 0.0 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43496.1 - 1.8e-10 40.1 24.4 2.8e-05 23.9 0.0 8.9 9 1 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG43496.1 - 3.7e-08 33.5 13.1 0.01 16.0 0.0 4.8 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CEG43496.1 - 5.1e-08 32.4 25.9 5.2e-06 26.1 0.1 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43496.1 - 7.2e-08 32.6 6.8 0.27 12.2 0.0 7.2 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43496.1 - 5.7e-07 29.1 1.8 0.026 14.5 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG43496.1 - 2.3e-06 27.8 6.8 3.8 7.9 0.0 6.9 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43496.1 - 8.4e-06 25.4 0.3 8.4e-06 25.4 0.3 3.0 3 0 0 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 CEG43496.1 - 1.5e-05 25.0 11.9 0.32 11.1 0.2 5.0 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CEG43496.1 - 9.2e-05 22.6 4.5 1.2 9.7 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43496.1 - 0.00043 20.7 20.0 0.36 11.4 0.1 6.9 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG43496.1 - 0.0015 18.3 0.2 11 6.0 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG43496.1 - 0.0034 17.5 0.4 0.89 9.7 0.1 4.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43496.1 - 0.004 17.8 11.8 0.32 11.7 0.0 6.4 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG43496.1 - 0.61 10.8 12.7 10 7.0 0.0 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat IPT PF01745.16 CEG43498.1 - 0.037 13.4 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase EGF_3 PF12947.7 CEG43504.1 - 0.051 13.8 0.1 0.067 13.4 0.1 1.2 1 0 0 1 1 1 0 EGF domain FYVE PF01363.21 CEG43506.1 - 8.7e-18 64.2 18.6 1.8e-17 63.2 9.8 2.6 2 0 0 2 2 2 2 FYVE zinc finger DEP PF00610.21 CEG43506.1 - 0.00094 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYVE_2 PF02318.16 CEG43506.1 - 0.0028 17.9 11.7 0.006 16.8 6.0 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger PLATZ PF04640.14 CEG43506.1 - 0.016 15.8 0.7 0.016 15.8 0.7 3.2 4 1 0 4 4 4 0 PLATZ transcription factor Peptidase_S24 PF00717.23 CEG43507.1 - 1.7e-10 40.7 0.2 5.8e-10 39.0 0.2 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CEG43507.1 - 0.0044 16.8 0.0 2.5 7.9 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CASP_C PF08172.12 CEG43508.1 - 3.4e-60 203.5 1.2 3.4e-60 203.5 1.2 3.7 3 2 1 4 4 4 1 CASP C terminal Csm1_N PF18504.1 CEG43508.1 - 0.012 15.9 4.0 0.012 15.9 4.0 7.2 5 2 1 7 7 7 0 Csm1 N-terminal domain SCO1-SenC PF02630.14 CEG43508.1 - 0.12 12.3 0.3 11 5.9 0.0 2.8 2 0 0 2 2 2 0 SCO1/SenC GAS PF13851.6 CEG43508.1 - 0.43 9.9 67.2 0.018 14.4 12.0 5.6 4 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding DUF2721 PF11026.8 CEG43508.1 - 0.48 10.3 0.0 0.48 10.3 0.0 4.8 6 2 1 7 7 7 0 Protein of unknown function (DUF2721) UPF0242 PF06785.11 CEG43508.1 - 8.1 6.5 55.5 0.47 10.5 0.1 5.8 2 1 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus RRM_1 PF00076.22 CEG43509.1 - 2.4e-09 36.9 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG43509.1 - 0.043 13.7 0.0 0.088 12.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif TPR_12 PF13424.6 CEG43510.1 - 3.1e-13 49.8 11.8 7.9e-06 26.1 0.3 4.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG43510.1 - 3.2e-10 39.4 9.7 0.04 14.1 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43510.1 - 1.3e-06 28.0 10.6 0.02 14.9 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43510.1 - 3.3e-05 23.7 9.0 1.8 8.9 0.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEG43510.1 - 4.8e-05 23.1 9.7 0.087 12.7 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43510.1 - 0.00037 20.2 14.2 2.2 8.3 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43510.1 - 0.00037 21.1 4.5 19 6.4 0.0 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG43510.1 - 0.004 16.6 3.4 0.61 9.4 0.8 2.4 2 0 0 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 CEG43510.1 - 0.01 16.4 4.8 33 5.4 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43510.1 - 0.18 11.5 0.8 13 5.6 0.1 3.1 3 0 0 3 3 3 0 TPR repeat polyprenyl_synt PF00348.17 CEG43511.1 - 6.4e-55 186.0 0.0 8.1e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Vps26 PF03643.15 CEG43512.1 - 1.5e-31 109.4 0.0 2.1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CEG43512.1 - 4.1e-05 23.7 0.1 0.00016 21.8 0.1 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo12 PF05032.12 CEG43512.1 - 0.0025 17.7 0.4 0.0061 16.4 0.4 1.7 1 0 0 1 1 1 1 Spo12 family DUF4207 PF13904.6 CEG43513.1 - 0.0072 16.0 17.7 0.12 12.1 6.8 2.8 1 1 0 2 2 2 2 Domain of unknown function (DUF4207) CBFD_NFYB_HMF PF00808.23 CEG43514.1 - 7.4e-16 58.2 0.4 1.2e-15 57.5 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEG43514.1 - 1.9e-11 44.5 0.6 4.1e-11 43.3 0.6 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CEG43514.1 - 0.071 13.4 0.2 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Nitr_red_assoc PF09655.10 CEG43514.1 - 0.11 13.1 1.6 0.16 12.6 0.4 1.7 1 1 1 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) TPT PF03151.16 CEG43515.1 - 3.3e-47 161.3 29.2 3.9e-47 161.0 29.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEG43515.1 - 3.8e-12 46.6 32.0 6e-07 29.7 11.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEG43515.1 - 1e-05 24.9 26.1 1.7e-05 24.2 26.1 1.4 1 0 0 1 1 1 1 UAA transporter family DUF2933 PF11666.8 CEG43515.1 - 0.0016 18.5 0.4 0.0041 17.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2933) PUNUT PF16913.5 CEG43515.1 - 0.0033 16.7 21.5 0.075 12.3 21.3 2.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF4570 PF15134.6 CEG43516.1 - 0.0049 16.9 0.3 0.0049 16.9 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) HemY_N PF07219.13 CEG43517.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.5 4 0 0 4 4 4 0 HemY protein N-terminus PIP5K PF01504.18 CEG43518.1 - 1.1e-73 247.9 0.0 1.5e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG43518.1 - 1.2e-05 24.7 5.8 3.3e-05 23.3 5.8 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Caa3_CtaG PF09678.10 CEG43518.1 - 0.0046 16.4 2.0 0.0097 15.4 2.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF2208 PF09973.9 CEG43518.1 - 0.14 11.8 2.1 0.31 10.6 2.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) EF1G PF00647.19 CEG43519.1 - 5e-40 135.9 0.3 5e-40 135.9 0.3 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CEG43519.1 - 5.8e-14 52.1 0.1 5.8e-14 52.1 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEG43519.1 - 1.5e-10 41.2 0.0 3.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEG43519.1 - 4.3e-08 33.1 0.1 1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEG43519.1 - 3.5e-06 27.1 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEG43519.1 - 9.7e-06 25.9 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HABP4_PAI-RBP1 PF04774.15 CEG43519.1 - 0.0075 17.1 0.7 0.015 16.1 0.7 1.4 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family GST_N_2 PF13409.6 CEG43519.1 - 0.022 15.1 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Mannosyl_trans3 PF11051.8 CEG43523.1 - 3.1e-18 66.1 0.0 7.6e-17 61.6 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 CEG43524.1 - 1.2e-17 64.1 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Terpene_synth PF01397.21 CEG43526.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain SUI1 PF01253.22 CEG43527.1 - 3e-19 69.3 1.1 5.2e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 YopX PF09643.10 CEG43527.1 - 0.1 12.7 1.0 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 YopX protein Voltage_CLC PF00654.20 CEG43528.1 - 2.6e-90 303.2 15.7 2.6e-90 303.2 15.7 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CEG43528.1 - 2.9e-07 30.8 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2976 PF11190.8 CEG43529.1 - 0.098 12.5 1.3 4.4 7.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF2254 PF10011.9 CEG43529.1 - 0.68 8.7 3.8 0.97 8.2 0.1 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2254) Saf_2TM PF18303.1 CEG43529.1 - 1.1 8.8 3.8 4.2 6.9 0.1 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Ras PF00071.22 CEG43531.1 - 8.5e-37 126.3 0.3 1.1e-36 125.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG43531.1 - 3.9e-17 62.6 0.0 6.4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG43531.1 - 6.2e-07 29.0 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG43531.1 - 0.00094 19.2 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CEG43531.1 - 0.0029 17.4 0.4 0.034 13.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CEG43531.1 - 0.011 15.7 0.1 1.6 8.6 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CEG43531.1 - 0.11 12.3 0.0 0.39 10.4 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ER PF01133.17 CEG43532.1 - 8.3e-39 131.6 0.4 1.9e-38 130.4 0.4 1.6 1 0 0 1 1 1 1 Enhancer of rudimentary Transmemb_17 PF09799.9 CEG43532.1 - 8.6e-17 61.7 4.1 1.7e-16 60.8 4.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein Skp1_POZ PF03931.15 CEG43532.1 - 1.1e-09 38.3 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 CEG43532.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ABC_transp_aux PF09822.9 CEG43533.1 - 4.5e-08 32.9 0.0 6.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 CEG43533.1 - 5e-06 25.6 0.0 9.7e-06 24.7 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta COPI_assoc PF08507.10 CEG43534.1 - 1.8e-16 60.4 8.9 2.1e-16 60.1 8.9 1.1 1 0 0 1 1 1 1 COPI associated protein SLATT_6 PF18169.1 CEG43534.1 - 0.56 9.8 3.5 0.92 9.1 3.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Glyco_transf_20 PF00982.21 CEG43535.1 - 2.4e-135 451.9 0.0 3e-135 451.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG43535.1 - 7.5e-49 166.0 0.0 1.7e-48 164.8 0.0 1.6 1 1 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 CEG43535.1 - 0.0094 15.5 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Hydrolase_6 PF13344.6 CEG43535.1 - 0.028 14.5 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 CEG43537.1 - 3.5e-59 196.7 1.3 2e-22 78.9 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein CH_2 PF06294.11 CEG43539.1 - 2.6e-20 72.3 0.3 9.6e-20 70.5 0.3 2.1 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 CEG43539.1 - 9.4e-09 35.5 0.0 5e-08 33.2 0.0 2.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG43539.1 - 0.00055 20.4 0.0 0.00055 20.4 0.0 3.9 4 2 0 4 4 4 1 AAA domain Hydin_ADK PF17213.3 CEG43539.1 - 0.01 16.1 0.0 0.01 16.1 0.0 3.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 CEG43539.1 - 0.012 15.7 0.0 0.012 15.7 0.0 3.9 5 1 0 5 5 5 0 AAA domain CH PF00307.31 CEG43539.1 - 0.016 15.4 0.5 0.055 13.7 0.2 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain AAA PF00004.29 CEG43539.1 - 0.016 15.6 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG43539.1 - 0.021 15.4 0.0 0.021 15.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 CEG43539.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.2 5 0 0 5 5 5 0 AAA domain Ribosomal_L13 PF00572.18 CEG43540.1 - 4.6e-54 182.0 0.2 5.6e-54 181.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Helicase_C PF00271.31 CEG43543.1 - 0.0024 18.2 0.6 0.012 16.0 0.1 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain TMA7 PF09072.10 CEG43543.1 - 6.5 7.7 11.5 0.23 12.3 5.1 1.9 2 0 0 2 2 2 0 Translation machinery associated TMA7 DAHP_synth_2 PF01474.16 CEG43544.1 - 1.1e-193 643.7 0.0 1.2e-193 643.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MIG-14_Wnt-bd PF06664.12 CEG43545.1 - 2.3e-47 161.6 22.2 8.3e-45 153.2 17.4 2.4 2 1 1 3 3 3 2 Wnt-binding factor required for Wnt secretion zf-RING_9 PF13901.6 CEG43546.1 - 0.0072 16.3 4.5 0.01 15.9 4.4 1.3 1 1 0 1 1 1 1 Putative zinc-RING and/or ribbon Pkinase PF00069.25 CEG43548.1 - 9.8e-21 74.3 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43548.1 - 5.9e-09 35.6 0.0 8.2e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEG43548.1 - 0.00046 20.8 1.4 0.00097 19.8 1.4 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain DNA_ligase_A_M PF01068.21 CEG43549.1 - 1.8e-35 122.5 0.0 2.9e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CEG43549.1 - 3e-33 115.6 0.6 6.1e-33 114.6 0.6 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 CEG43549.1 - 3.4e-13 49.8 0.0 1.1e-05 25.7 0.0 2.7 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 CEG43549.1 - 2.5e-12 47.2 0.0 6.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 CEG43549.1 - 9e-09 35.6 0.0 0.0036 17.7 0.1 3.4 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 CEG43549.1 - 1.4e-05 25.5 0.0 3.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 RNA ligase PTCB-BRCT PF12738.7 CEG43549.1 - 0.00015 21.7 0.1 0.047 13.6 0.0 2.9 2 0 0 2 2 2 1 twin BRCT domain DNA_ligase_IV PF11411.8 CEG43549.1 - 0.00021 21.4 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 CEG43549.1 - 0.002 18.4 0.0 0.72 10.2 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DNA_pol_B_palm PF14792.6 CEG43550.1 - 7.5e-30 103.5 0.0 1.9e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CEG43550.1 - 5.8e-20 71.2 0.0 1.6e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CEG43550.1 - 3.2e-17 62.1 0.0 1.7e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CEG43550.1 - 1.6e-09 38.0 0.0 4.6e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 CEG43550.1 - 0.00023 21.7 0.0 0.00065 20.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Mem_trans PF03547.18 CEG43550.1 - 0.67 8.3 5.0 1.7 6.9 5.0 1.6 1 0 0 1 1 1 0 Membrane transport protein Peptidase_M22 PF00814.25 CEG43551.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Peptidase_C13 PF01650.18 CEG43553.1 - 1.9e-41 142.3 0.2 2.3e-41 142.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 CEG43553.1 - 0.063 13.2 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Caspase domain BSD PF03909.17 CEG43554.1 - 1.8e-16 59.9 0.3 7.4e-11 41.9 0.4 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CEG43554.1 - 8.1e-11 42.1 0.0 3.2e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DUF2458 PF10454.9 CEG43554.1 - 0.00056 19.6 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Methyltransf_16 PF10294.9 CEG43555.1 - 2.3e-28 99.1 0.0 3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG43555.1 - 4.8e-11 42.6 0.0 6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG43555.1 - 2.8e-08 33.5 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG43555.1 - 0.00015 22.4 0.2 0.00058 20.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG43555.1 - 0.00043 20.1 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG43555.1 - 0.0026 18.4 0.0 0.0062 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG43555.1 - 0.0063 16.4 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG43555.1 - 0.0093 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 CEG43555.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DYW_deaminase PF14432.6 CEG43556.1 - 1.8e-28 98.9 0.1 5.4e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 DYW family of nucleic acid deaminases CagE_TrbE_VirB PF03135.14 CEG43556.1 - 0.0062 16.7 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system GH131_N PF18271.1 CEG43558.1 - 7.3e-41 140.5 0.0 8.8e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain OpgC_C PF10129.9 CEG43558.1 - 0.19 10.6 0.2 0.3 9.9 0.2 1.2 1 0 0 1 1 1 0 OpgC protein GH131_N PF18271.1 CEG43559.1 - 2.2e-46 158.7 0.2 2.7e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG43559.1 - 0.0067 16.3 0.2 0.019 14.8 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide lyase Gp_UL130 PF11668.8 CEG43559.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 DUF4371 PF14291.6 CEG43560.1 - 0.049 13.3 0.4 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Cys_Met_Meta_PP PF01053.20 CEG43562.1 - 7.9e-130 432.8 0.0 9.4e-130 432.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEG43562.1 - 2.6e-09 36.5 0.0 4.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEG43562.1 - 8.9e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 CEG43562.1 - 0.00019 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.17 CEG43562.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Asn_synthase PF00733.21 CEG43563.1 - 1.8e-94 317.3 1.9 2e-56 192.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CEG43563.1 - 5.5e-40 136.1 0.0 2.2e-39 134.2 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEG43563.1 - 6e-28 97.7 0.0 1.1e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEG43563.1 - 5.5e-11 42.4 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CEG43563.1 - 0.005 16.0 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 CEG43563.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 CEG43563.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TTL PF03133.15 CEG43564.1 - 6.3e-66 222.5 2.8 6.3e-66 222.5 2.8 4.7 5 0 0 5 5 5 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CEG43564.1 - 0.0004 19.7 0.0 0.033 13.4 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Pkinase_Tyr PF07714.17 CEG43565.1 - 2.9e-48 164.4 0.0 3.9e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG43565.1 - 2.6e-47 161.4 0.0 3.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 CEG43565.1 - 3e-10 39.7 10.9 0.0088 15.8 0.2 5.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CEG43565.1 - 3e-08 33.8 14.1 0.43 11.1 2.4 5.8 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG43565.1 - 0.00015 21.5 8.2 5 7.4 0.0 6.6 6 1 1 7 7 7 1 Leucine Rich repeat Pkinase_fungal PF17667.1 CEG43565.1 - 0.0033 16.2 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FNIP PF05725.12 CEG43565.1 - 0.0091 16.1 7.5 0.32 11.2 0.2 4.8 4 1 0 5 5 5 1 FNIP Repeat LRR_5 PF13306.6 CEG43565.1 - 0.076 13.0 3.6 9.7 6.2 0.0 3.5 1 1 3 4 4 4 0 BspA type Leucine rich repeat region (6 copies) PDZ_4 PF17816.1 CEG43565.1 - 0.18 12.2 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain LRR_1 PF00560.33 CEG43565.1 - 0.4 11.4 4.5 1.1e+02 4.0 0.0 5.6 5 2 0 5 5 5 0 Leucine Rich Repeat PX PF00787.24 CEG43566.1 - 3.7e-07 30.1 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.14 CEG43566.1 - 0.066 12.4 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PhoLip_ATPase_C PF16212.5 CEG43567.1 - 3.3e-62 210.5 20.3 3.3e-62 210.5 20.3 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG43567.1 - 1.5e-20 72.6 0.1 4.8e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG43567.1 - 5.2e-10 40.0 0.0 0.0036 17.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG43567.1 - 4.8e-08 33.0 0.0 1.5e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG43567.1 - 7e-07 28.9 0.0 2.5e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG43567.1 - 0.00011 22.1 0.0 0.00031 20.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG43567.1 - 0.09 13.2 0.0 9.6 6.6 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.10 CEG43567.1 - 2.5 7.9 8.8 5.6 6.8 8.8 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ELMO_CED12 PF04727.13 CEG43568.1 - 2.2e-06 27.9 0.0 5.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 ELMO/CED-12 family DUF3255 PF11631.8 CEG43568.1 - 0.052 13.4 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) FHA PF00498.26 CEG43569.1 - 6.7e-10 39.2 0.2 1.4e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG43569.1 - 0.0021 18.3 2.6 0.0033 17.7 0.0 2.6 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain MerR-DNA-bind PF09278.11 CEG43569.1 - 0.0036 17.8 1.5 0.011 16.2 1.5 1.9 1 0 0 1 1 1 1 MerR, DNA binding Osmo_CC PF08946.10 CEG43569.1 - 0.034 14.4 1.4 0.23 11.7 0.5 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF5616 PF18481.1 CEG43569.1 - 0.04 14.2 0.2 0.096 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) AAA_31 PF13614.6 CEG43569.1 - 0.054 13.4 1.8 1.2 9.0 0.6 2.4 2 0 0 2 2 2 0 AAA domain DUF3751 PF12571.8 CEG43569.1 - 0.058 13.5 0.9 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Phage tail-collar fibre protein Nsp1_C PF05064.13 CEG43569.1 - 0.096 12.5 2.0 0.23 11.3 2.0 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region Sec34 PF04136.15 CEG43569.1 - 0.1 12.5 3.0 0.22 11.4 3.0 1.5 1 0 0 1 1 1 0 Sec34-like family SnoaL PF07366.12 CEG43570.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase LEH PF07858.12 CEG43570.1 - 0.056 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain ArfGap PF01412.18 CEG43571.1 - 9.9e-16 57.9 6.3 1.7e-15 57.1 6.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.6 CEG43571.1 - 1.8 8.1 4.8 9.3 5.8 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1126 PF06565.12 CEG43574.1 - 6.7e-87 286.2 3.4 3.4e-31 107.2 0.5 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain DSS1_SEM1 PF05160.13 CEG43575.1 - 0.4 10.8 5.9 0.33 11.1 3.4 1.9 1 1 1 2 2 2 0 DSS1/SEM1 family Fumble PF03630.14 CEG43576.1 - 7.5e-113 377.0 0.2 8.8e-113 376.8 0.2 1.0 1 0 0 1 1 1 1 Fumble Glyco_hydro_17 PF00332.18 CEG43579.1 - 2.5e-16 60.2 0.4 7.9e-09 35.5 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 S-antigen PF05756.11 CEG43580.1 - 0.062 13.7 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 S-antigen protein Myb_DNA-bind_4 PF13837.6 CEG43581.1 - 0.054 13.9 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RRM_3 PF08777.11 CEG43581.1 - 0.29 11.2 10.2 14 5.8 0.0 4.9 3 2 0 4 4 4 0 RNA binding motif Importin_rep_4 PF18808.1 CEG43583.1 - 5.3e-20 71.5 2.9 9.5e-19 67.5 0.1 4.3 4 0 0 4 4 4 1 Importin repeat HEAT PF02985.22 CEG43583.1 - 2.2e-13 49.2 5.6 0.021 15.1 0.0 8.6 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CEG43583.1 - 5.9e-10 39.4 7.2 4.6e-05 23.7 0.0 6.8 5 2 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CEG43583.1 - 2.2e-08 34.4 13.8 0.00078 19.9 0.0 8.1 6 2 2 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.20 CEG43583.1 - 1.1e-05 24.2 0.8 0.068 11.7 0.0 3.6 2 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 CEG43583.1 - 1.5e-05 24.2 5.7 0.0006 19.0 0.1 4.1 3 2 1 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 CEG43583.1 - 0.00012 22.6 1.0 0.85 10.3 0.0 4.8 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CEG43583.1 - 0.00017 21.4 0.7 0.00017 21.4 0.7 3.9 5 1 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 CEG43583.1 - 0.0013 18.7 5.7 1.8 8.4 0.1 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF3385) IBN_N PF03810.19 CEG43583.1 - 0.03 14.2 1.3 2.2 8.3 0.1 3.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain Fis1_TPR_C PF14853.6 CEG43584.1 - 6.3e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CEG43584.1 - 7.5e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.6 CEG43584.1 - 0.00026 21.4 0.3 0.18 12.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43584.1 - 0.00083 19.3 0.2 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43584.1 - 0.00083 20.0 2.3 0.18 12.7 0.4 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG43584.1 - 0.0021 18.3 0.2 0.0038 17.4 0.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEG43584.1 - 0.0027 17.8 0.0 0.0076 16.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43584.1 - 0.0034 17.3 0.5 0.14 12.3 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43584.1 - 0.032 14.9 1.2 0.21 12.3 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.24 CEG43586.1 - 9.5e-20 70.0 14.8 2e-10 40.3 3.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG43586.1 - 2.7e-14 52.6 14.8 4.3e-07 29.8 5.1 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEG43586.1 - 9.4e-13 47.6 12.4 2.1e-07 30.6 2.2 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG43586.1 - 3e-06 27.5 8.8 0.0011 19.3 1.2 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG43586.1 - 0.00034 21.3 9.3 0.028 15.1 0.8 2.2 1 1 1 2 2 2 2 Torus domain YIF1 PF03878.15 CEG43588.1 - 3.8e-58 196.8 2.9 5.3e-58 196.4 2.9 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CEG43588.1 - 7.3e-10 38.8 1.9 1.2e-09 38.1 1.9 1.3 1 0 0 1 1 1 1 Yip1 domain DCP2 PF05026.13 CEG43589.1 - 5.7e-27 93.9 3.3 1.1e-26 93.0 3.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CEG43589.1 - 4.9e-16 59.0 0.0 8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PRP3 PF08572.10 CEG43590.1 - 7.6e-62 209.0 4.3 1.7e-61 207.8 4.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CEG43590.1 - 2.2e-43 147.9 0.9 6.1e-43 146.4 0.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) AGT PF11440.8 CEG43590.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Retrotran_gag_2 PF14223.6 CEG43591.1 - 3.9e-38 130.2 0.4 5.5e-38 129.7 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG43591.1 - 7.8e-06 25.7 3.5 7.8e-06 25.7 3.5 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG43591.1 - 3.7e-05 23.4 3.0 6.2e-05 22.7 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEG43591.1 - 0.0055 16.4 2.2 0.011 15.4 2.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CEG43591.1 - 0.006 16.5 1.4 0.01 15.8 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEG43591.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein eIF3g PF12353.8 CEG43591.1 - 0.032 14.6 0.2 0.058 13.8 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF918 PF06033.11 CEG43592.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Hydrolase_4 PF12146.8 CEG43593.1 - 0.00086 18.6 0.0 0.37 10.0 0.0 3.2 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CEG43593.1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.1 1 1 0 1 1 1 0 TAP-like protein Trypsin PF00089.26 CEG43594.1 - 6e-20 72.0 0.0 6.9e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CEG43595.1 - 9.4e-26 91.0 0.0 1.1e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Pollen_allerg_1 PF01357.21 CEG43595.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Pollen allergen Trypsin PF00089.26 CEG43596.1 - 6.1e-40 137.4 0.1 6.9e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Trypsin Pyridoxal_deC PF00282.19 CEG43597.1 - 1.2e-15 57.1 0.0 2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CEG43597.1 - 6.6e-08 31.9 0.0 2.4e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Rhomboid PF01694.22 CEG43598.1 - 1.4e-17 64.1 10.7 2.2e-17 63.5 10.7 1.3 1 0 0 1 1 1 1 Rhomboid family CCDC50_N PF15295.6 CEG43598.1 - 0.12 12.6 0.5 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus His_Phos_1 PF00300.22 CEG43599.1 - 1.3e-08 34.7 0.1 0.4 10.3 0.0 4.1 4 0 0 4 4 4 4 Histidine phosphatase superfamily (branch 1) Rhomboid PF01694.22 CEG43600.1 - 5.3e-05 23.3 5.9 0.00034 20.6 0.7 2.5 3 0 0 3 3 3 2 Rhomboid family RabGAP-TBC PF00566.18 CEG43601.1 - 3.9e-36 124.7 1.0 3.7e-35 121.6 0.2 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain TolB_N PF04052.13 CEG43601.1 - 0.089 13.0 0.0 6.1 7.1 0.0 2.8 3 0 0 3 3 3 0 TolB amino-terminal domain BtrH_N PF14399.6 CEG43601.1 - 0.16 12.2 0.1 0.45 10.8 0.1 1.7 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Dimer_Tnp_hAT PF05699.14 CEG43602.1 - 2.9e-05 23.8 0.0 6.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HMG_box PF00505.19 CEG43605.1 - 6.4e-28 97.0 1.7 3.2e-23 81.9 0.2 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEG43605.1 - 3.6e-19 69.1 1.3 2.5e-14 53.6 0.4 2.2 2 0 0 2 2 2 2 HMG-box domain Ribosomal_S25 PF03297.15 CEG43605.1 - 0.056 13.6 0.3 0.13 12.4 0.1 1.6 2 0 0 2 2 2 0 S25 ribosomal protein zf-CCCH PF00642.24 CEG43606.1 - 1e-05 25.3 13.3 0.0003 20.6 2.9 2.5 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG43606.1 - 0.012 15.7 12.7 0.038 14.1 2.7 3.2 2 1 0 2 2 2 0 Zinc finger domain PUA PF01472.20 CEG43606.1 - 0.033 14.2 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 PUA domain PQQ PF01011.21 CEG43606.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat zf-CCCH_2 PF14608.6 CEG43606.1 - 8.6 7.0 16.7 5.8 7.6 5.1 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Mago-bind PF09282.10 CEG43607.1 - 1.6e-11 43.8 2.7 1.6e-11 43.8 2.7 1.9 2 0 0 2 2 2 1 Mago binding TMCO5 PF14992.6 CEG43607.1 - 0.042 13.4 9.9 0.057 13.0 9.9 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4200 PF13863.6 CEG43607.1 - 0.8 10.1 11.7 1.5 9.2 9.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.16 CEG43607.1 - 1.3 7.8 2.8 1.4 7.8 2.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein GCN5L1 PF06320.13 CEG43607.1 - 2.4 8.3 9.3 1.6 8.9 5.2 2.5 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Jnk-SapK_ap_N PF09744.9 CEG43607.1 - 5.4 7.2 14.4 16 5.7 11.6 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DEAD PF00270.29 CEG43608.1 - 1.7e-27 96.3 0.0 5.3e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG43608.1 - 2e-12 47.4 0.0 1.7e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 CEG43608.1 - 3e-09 37.5 0.2 1.1e-08 35.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.15 CEG43608.1 - 7.2e-06 26.1 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEG43608.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CEG43608.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TetR_C_9 PF14514.6 CEG43609.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Aldose_epim PF01263.20 CEG43610.1 - 2.5e-34 119.0 0.6 2.9e-34 118.8 0.6 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ehbp PF10622.9 CEG43610.1 - 0.028 14.4 0.3 0.17 11.9 0.0 2.3 2 1 1 3 3 3 0 Energy-converting hydrogenase B subunit P (EhbP) Pyrid_oxidase_2 PF13883.6 CEG43611.1 - 1.4e-24 87.0 0.3 7.9e-16 58.5 0.1 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase HNH_2 PF13391.6 CEG43615.1 - 9.2e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease zf-TRM13_CCCH PF11722.8 CEG43616.1 - 0.0071 16.1 0.7 0.019 14.7 0.7 1.8 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein LCD1 PF09798.9 CEG43616.1 - 0.13 10.8 2.7 0.16 10.4 2.7 1.2 1 1 0 1 1 1 0 DNA damage checkpoint protein Fer4_22 PF17179.4 CEG43617.1 - 0.029 15.2 0.5 0.045 14.6 0.5 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-CCHC PF00098.23 CEG43617.1 - 0.034 14.2 1.2 0.069 13.3 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Pox_A32 PF04665.12 CEG43618.1 - 5.5e-08 32.6 0.3 0.00035 20.1 0.0 2.0 2 0 0 2 2 2 2 Poxvirus A32 protein RNA_helicase PF00910.22 CEG43618.1 - 0.038 14.4 0.0 0.1 13.0 0.0 1.8 1 1 1 2 2 2 0 RNA helicase Syd PF07348.12 CEG43618.1 - 0.097 12.3 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Syd protein (SUKH-2) Exo_endo_phos_2 PF14529.6 CEG43623.1 - 8e-05 22.5 0.4 0.00018 21.3 0.4 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEG43623.1 - 0.17 11.4 1.5 0.28 10.7 0.6 1.8 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family VP4_helical PF17478.2 CEG43626.1 - 0.0054 16.2 1.2 0.0073 15.8 1.2 1.1 1 0 0 1 1 1 1 Rotavirus VP4 helical domain Flagellin_N PF00669.20 CEG43626.1 - 0.0066 16.6 8.9 0.028 14.5 2.2 2.7 1 1 2 3 3 3 1 Bacterial flagellin N-terminal helical region COG2 PF06148.11 CEG43626.1 - 0.017 15.2 10.5 0.53 10.4 0.5 3.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2046 PF09755.9 CEG43626.1 - 0.019 14.2 7.8 0.047 12.9 1.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Golgin_A5 PF09787.9 CEG43626.1 - 0.037 13.5 9.4 0.05 13.1 9.0 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 Med9 PF07544.13 CEG43626.1 - 0.07 13.2 2.8 1.2 9.2 1.7 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PEP-utilisers_N PF05524.13 CEG43626.1 - 0.1 12.8 6.1 0.25 11.5 0.9 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal AAA_13 PF13166.6 CEG43626.1 - 0.14 10.7 8.1 0.18 10.4 8.1 1.1 1 0 0 1 1 1 0 AAA domain Gon7 PF08738.10 CEG43626.1 - 0.19 11.9 2.7 0.47 10.6 0.5 2.4 1 1 1 2 2 2 0 Gon7 family TolA_bind_tri PF16331.5 CEG43626.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.7 2 2 1 4 4 4 0 TolA binding protein trimerisation FlxA PF14282.6 CEG43626.1 - 0.25 11.4 8.9 0.24 11.4 0.9 3.0 1 1 2 3 3 3 0 FlxA-like protein Spc7 PF08317.11 CEG43626.1 - 0.3 9.9 13.5 0.099 11.5 8.1 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein MIP-T3_C PF17749.1 CEG43626.1 - 0.37 10.7 5.0 0.62 10.0 4.1 1.7 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Fez1 PF06818.15 CEG43626.1 - 0.58 10.6 13.6 1.3 9.5 13.6 1.6 1 1 0 1 1 1 0 Fez1 NPV_P10 PF05531.12 CEG43626.1 - 0.68 10.4 9.6 2.5 8.6 1.2 2.8 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CEG43626.1 - 0.98 8.4 9.1 1.3 8.0 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RILP PF11461.8 CEG43626.1 - 1.2 9.4 4.7 0.74 10.1 0.2 2.8 3 0 0 3 3 3 0 Rab interacting lysosomal protein Allexi_40kDa PF05549.11 CEG43626.1 - 1.5 8.3 4.1 3.5 7.1 0.8 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CEP63 PF17045.5 CEG43626.1 - 1.6 8.6 13.1 0.18 11.7 4.9 2.4 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa FliJ PF02050.16 CEG43626.1 - 2.1 8.6 9.5 0.82 9.9 1.4 2.8 1 1 2 3 3 3 0 Flagellar FliJ protein SlyX PF04102.12 CEG43626.1 - 2.7 8.7 11.7 5 7.8 0.5 3.6 2 1 1 3 3 3 0 SlyX Apt1 PF10351.9 CEG43626.1 - 4.4 6.1 7.9 0.9 8.3 1.7 2.2 1 1 1 2 2 2 0 Golgi-body localisation protein domain DUF4140 PF13600.6 CEG43626.1 - 5.4 7.5 11.6 17 5.9 0.7 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.12 CEG43626.1 - 6.8 5.1 5.4 3.7 6.0 3.3 1.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 CEG43626.1 - 9.4 7.2 11.0 2.1 9.3 4.8 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Sin3_corepress PF08295.12 CEG43627.1 - 0.0024 17.9 1.1 0.0024 17.9 1.1 4.1 4 1 1 5 5 5 1 Sin3 family co-repressor TPR_MLP1_2 PF07926.12 CEG43627.1 - 0.006 16.6 63.5 0.049 13.7 5.6 5.3 1 1 4 5 5 5 3 TPR/MLP1/MLP2-like protein Chi-conotoxin PF16981.5 CEG43627.1 - 0.25 11.6 1.3 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily APG6_N PF17675.1 CEG43627.1 - 0.4 11.2 71.3 0.9 10.1 8.6 5.7 1 1 4 5 5 5 0 Apg6 coiled-coil region FPP PF05911.11 CEG43627.1 - 0.68 8.0 55.1 1.3 7.1 28.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 CEG43627.1 - 1.2 8.6 62.1 0.017 14.7 12.0 3.0 1 1 1 3 3 3 0 Intermediate filament protein ERM PF00769.19 CEG43627.1 - 1.2 8.8 67.4 1.6 8.5 34.3 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family GAS PF13851.6 CEG43627.1 - 3.9 6.8 61.2 1.5 8.1 3.9 4.4 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CEG43627.1 - 5.1 7.1 65.5 2.8 8.0 1.6 4.8 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RPE65 PF03055.15 CEG43627.1 - 5.5 6.1 5.6 0.87 8.7 0.9 1.9 1 1 1 2 2 2 0 Retinal pigment epithelial membrane protein DUF3584 PF12128.8 CEG43627.1 - 9.7 3.5 58.8 0.92 6.9 35.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Peroxidase_2 PF01328.17 CEG43632.1 - 1.3e-29 104.1 0.0 1.4e-29 103.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 FIBP PF05427.11 CEG43633.1 - 5.3e-38 131.2 0.0 6.5e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) SAM_3 PF18016.1 CEG43633.1 - 0.12 12.2 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Enolase_C PF00113.22 CEG43639.1 - 0.16 11.2 0.7 0.22 10.7 0.7 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain E1-E2_ATPase PF00122.20 CEG43640.1 - 1.7e-38 132.0 0.2 2.6e-38 131.4 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CEG43640.1 - 6.7e-16 57.7 0.1 1.1e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus V_cholerae_RfbT PF05575.11 CEG43641.1 - 0.11 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Pox_A32 PF04665.12 CEG43648.1 - 0.0013 18.3 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein ResIII PF04851.15 CEG43648.1 - 0.0025 17.8 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 CEG43648.1 - 0.033 14.3 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 CEG43648.1 - 0.078 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain FYVE PF01363.21 CEG43650.1 - 9e-05 22.5 12.0 0.00023 21.2 12.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF866 PF05907.13 CEG43650.1 - 0.11 12.4 2.4 0.21 11.5 2.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) IBR PF01485.21 CEG43650.1 - 2.4 8.5 8.2 1.9 8.8 5.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CEG43651.1 - 0.00026 21.1 9.7 0.00051 20.1 9.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG43651.1 - 0.05 13.8 12.3 0.32 11.2 11.1 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger zf-CXXC PF02008.20 CEG43651.1 - 0.64 10.1 7.8 0.39 10.8 3.9 2.3 2 0 0 2 2 2 0 CXXC zinc finger domain Utp14 PF04615.13 CEG43652.1 - 0.0047 15.6 2.6 0.0047 15.6 2.6 2.0 2 0 0 2 2 2 1 Utp14 protein SPT6_acidic PF14632.6 CEG43652.1 - 6.4 7.4 9.5 0.2 12.3 1.0 2.4 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Elicitin PF00964.17 CEG43653.1 - 3.4e-06 27.1 0.4 6.4e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 Elicitin zf-MYND PF01753.18 CEG43654.1 - 0.00017 21.6 4.9 0.00017 21.6 4.9 2.1 2 0 0 2 2 2 1 MYND finger Methyltransf_23 PF13489.6 CEG43654.1 - 0.0029 17.5 0.1 0.013 15.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain IZUMO PF15005.6 CEG43654.1 - 0.021 15.4 3.7 0.25 11.8 0.0 3.6 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated PhetRS_B1 PF18262.1 CEG43654.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Methyltransf_25 PF13649.6 CEG43654.1 - 0.15 12.8 0.0 0.41 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_ABP1_N PF18107.1 CEG43655.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Nucleoporin_FG PF13634.6 CEG43658.1 - 0.028 15.3 54.0 0.34 11.8 5.1 7.3 2 1 3 5 5 5 0 Nucleoporin FG repeat region SBF2 PF12335.8 CEG43658.1 - 0.062 12.9 1.9 0.15 11.6 1.9 1.6 1 0 0 1 1 1 0 Myotubularin protein FYVE PF01363.21 CEG43659.1 - 8.4e-16 57.9 12.4 2e-15 56.7 12.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 CEG43659.1 - 1.5e-10 41.8 0.1 4.1e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEG43659.1 - 1.3e-07 31.9 0.0 3.4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 CEG43659.1 - 0.0011 19.1 7.4 0.0037 17.5 7.4 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger GAF_3 PF13492.6 CEG43659.1 - 0.02 15.2 0.0 0.075 13.4 0.0 2.0 1 1 0 1 1 1 0 GAF domain WD40 PF00400.32 CEG43660.1 - 1.3e-45 152.4 9.9 3.9e-08 33.8 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CEG43660.1 - 3.2e-22 78.6 12.6 9.2e-22 77.1 12.6 1.8 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CEG43660.1 - 9.6e-16 57.9 0.0 1.7e-05 25.1 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG43660.1 - 1.3e-07 31.0 0.1 0.26 10.2 0.0 4.2 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CEG43660.1 - 0.00029 20.3 0.0 0.65 9.3 0.0 3.4 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CEG43660.1 - 0.0012 18.7 0.1 15 5.7 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 CEG43660.1 - 0.0014 18.0 0.0 5.6 6.2 0.0 3.4 4 0 0 4 4 4 2 WD40-like domain DUF1525 PF07511.11 CEG43660.1 - 0.47 10.6 5.7 2.1 8.5 5.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) TSNAXIP1_N PF15739.5 CEG43660.1 - 0.97 9.8 14.8 0.34 11.3 8.8 3.1 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus MMS19_N PF14500.6 CEG43660.1 - 2.4 7.7 7.8 4.1 6.9 5.1 2.1 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II SAC3 PF12209.8 CEG43660.1 - 2.8 8.2 5.4 31 4.8 0.2 3.4 2 1 1 3 3 3 0 Leucine permease transcriptional regulator helical domain UCH PF00443.29 CEG43661.1 - 1.5e-66 224.6 0.2 1.5e-66 224.6 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEG43661.1 - 6e-12 46.0 3.0 9.6e-12 45.4 0.6 2.6 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CEG43661.1 - 3.2e-06 27.0 17.7 0.027 14.1 0.1 4.4 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase MBT PF02820.18 CEG43661.1 - 0.00015 22.0 1.1 0.67 10.3 0.2 3.0 3 0 0 3 3 3 2 mbt repeat Tudor_4 PF18358.1 CEG43661.1 - 0.00094 18.7 0.8 0.0027 17.2 0.5 2.1 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain Tudor-knot PF11717.8 CEG43661.1 - 0.017 15.0 1.0 0.069 13.0 1.0 2.1 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain USP7_C2 PF14533.6 CEG43661.1 - 0.042 13.5 0.1 0.042 13.5 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal SPX PF03105.19 CEG43661.1 - 2.4 8.0 21.9 5.3 6.9 21.9 1.5 1 0 0 1 1 1 0 SPX domain Ribonuclease_T2 PF00445.18 CEG43662.1 - 2.5e-26 93.0 6.7 3.9e-26 92.4 6.7 1.3 1 1 0 1 1 1 1 Ribonuclease T2 family AAA_6 PF12774.7 CEG43665.1 - 1.7e-143 477.6 0.0 9.8e-143 475.0 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG43665.1 - 1e-130 436.5 12.4 1e-130 436.5 12.4 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG43665.1 - 4.3e-111 371.0 0.0 1.2e-110 369.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CEG43665.1 - 3.7e-104 347.7 4.3 4.5e-103 344.1 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CEG43665.1 - 6.4e-89 296.8 5.2 6.4e-89 296.8 5.2 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG43665.1 - 3.7e-79 264.5 0.1 1.1e-73 246.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG43665.1 - 5.6e-55 185.6 0.0 2e-54 183.8 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG43665.1 - 4.7e-51 173.8 9.4 8.8e-51 172.9 9.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG43665.1 - 4e-46 156.0 0.0 1.6e-44 150.8 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG43665.1 - 2.9e-31 108.2 0.0 9.2e-31 106.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG43665.1 - 4.6e-22 78.1 0.0 7.4e-21 74.2 0.1 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CEG43665.1 - 3.2e-17 62.8 0.0 0.00014 21.9 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG43665.1 - 3e-09 37.3 0.7 0.33 11.2 0.0 6.8 6 0 0 6 6 6 2 AAA domain AAA PF00004.29 CEG43665.1 - 3.9e-06 27.3 0.6 1.8 9.0 0.0 4.9 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEG43665.1 - 4.4e-06 25.9 0.0 0.08 12.0 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 CEG43665.1 - 3.2e-05 24.4 1.5 5.2 7.4 0.0 5.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 CEG43665.1 - 0.0003 21.4 0.0 0.21 12.1 0.0 3.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CEG43665.1 - 0.00097 18.6 0.2 0.1 12.0 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF853 PF05872.12 CEG43665.1 - 0.0081 14.8 1.8 0.64 8.5 0.1 3.1 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.22 CEG43665.1 - 0.0089 16.4 0.8 7.9 6.9 0.0 3.7 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 CEG43665.1 - 0.013 15.2 0.3 7.9 6.2 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 CEG43665.1 - 0.013 15.8 0.4 25 5.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 CEG43665.1 - 0.017 14.8 1.1 1.8 8.4 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_DNA_Zn_bi PF03728.13 CEG43665.1 - 0.029 14.9 0.1 0.09 13.3 0.1 1.8 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain NACHT PF05729.12 CEG43665.1 - 0.04 13.8 0.6 2.5 8.0 0.1 3.7 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 CEG43665.1 - 0.041 13.3 0.5 0.59 9.5 0.1 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CEG43665.1 - 0.042 14.0 5.6 0.093 12.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CEG43665.1 - 0.13 12.5 0.8 22 5.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CEG43665.1 - 0.17 11.6 4.1 4.4 7.0 0.1 3.6 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 CEG43665.1 - 8.5 6.2 6.6 27 4.6 0.1 3.7 4 0 0 4 4 4 0 Rad17 P-loop domain RVT_2 PF07727.14 CEG43667.1 - 2.8e-09 37.0 0.1 4.2e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 CEG43668.1 - 7.7e-21 74.5 0.1 1.4e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CEG43668.1 - 7.8e-08 32.2 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 CEG43668.1 - 0.00016 21.7 0.0 0.00057 20.0 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEG43668.1 - 0.0021 17.8 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_1 PF00126.27 CEG43668.1 - 0.0034 17.3 1.0 0.021 14.8 0.3 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.13 CEG43668.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 CEG43668.1 - 0.062 13.2 0.1 0.38 10.7 0.0 2.3 3 0 0 3 3 3 0 MarR family HTH_3 PF01381.22 CEG43668.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix YdaS_antitoxin PF15943.5 CEG43668.1 - 0.084 12.8 0.8 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF134 PF02001.16 CEG43668.1 - 0.093 13.3 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 DUF4498 PF14926.6 CEG43668.1 - 0.15 11.4 0.9 0.52 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4498) LRR_6 PF13516.6 CEG43669.1 - 6.8e-08 32.0 0.1 0.017 15.1 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeat zf-C2H2 PF00096.26 CEG43670.1 - 3e-19 68.3 28.4 2.6e-06 27.6 0.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type FKBP_C PF00254.28 CEG43670.1 - 4.8e-19 68.5 0.0 1.2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-H2C2_2 PF13465.6 CEG43670.1 - 6.4e-15 54.8 28.0 8.8e-06 25.9 0.4 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEG43670.1 - 1.2e-13 50.6 23.6 0.0026 18.5 0.5 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEG43670.1 - 3.6e-05 23.4 18.4 0.063 13.1 1.7 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CEG43670.1 - 0.00081 19.1 17.6 0.027 14.2 0.6 4.4 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CEG43670.1 - 0.0023 17.9 17.4 0.11 12.6 2.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEG43670.1 - 0.0069 16.6 9.5 5.7 7.4 0.1 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG43670.1 - 0.024 15.0 9.9 16 6.1 1.7 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type BRCA-2_helical PF09169.10 CEG43670.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 BRCA2, helical zf-C2H2_8 PF15909.5 CEG43670.1 - 0.042 14.1 1.5 0.042 14.1 1.5 2.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon Ogr_Delta PF04606.12 CEG43670.1 - 1.1 9.2 15.3 4 7.5 0.8 4.2 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 CEG43670.1 - 1.5 9.5 7.2 4.8 7.9 0.6 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain zf_ZIC PF18366.1 CEG43670.1 - 2 8.6 6.4 26 5.0 0.4 3.5 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_9 PF16293.5 CEG43670.1 - 2 8.3 7.8 41 4.1 0.1 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) SWIB PF02201.18 CEG43671.1 - 1.2e-59 198.1 1.8 7.7e-29 99.4 0.1 2.8 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 CEG43671.1 - 2.5e-17 62.6 2.2 1.1e-16 60.5 2.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain YL1 PF05764.13 CEG43671.1 - 0.0022 18.2 13.3 0.0043 17.2 6.4 2.2 2 0 0 2 2 2 1 YL1 nuclear protein V_ATPase_I PF01496.19 CEG43671.1 - 0.036 12.0 8.4 0.1 10.5 4.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PBP1_TM PF14812.6 CEG43671.1 - 0.52 10.7 13.2 0.38 11.2 5.5 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 CEG43671.1 - 0.65 10.3 11.1 1.1 9.5 7.3 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 CEG43671.1 - 1.1 9.0 14.0 0.32 10.8 8.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sin3a_C PF16879.5 CEG43671.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.5 3 2 0 3 3 2 0 C-terminal domain of Sin3a protein PcfK PF14058.6 CEG43671.1 - 1.3 9.3 14.6 1 9.6 6.1 2.4 2 0 0 2 2 2 0 PcfK-like protein DUF2828 PF11443.8 CEG43671.1 - 1.4 6.9 11.5 0.035 12.2 5.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF2052 PF09747.9 CEG43671.1 - 1.6 8.8 16.2 1.3 9.1 11.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 CEG43671.1 - 7.4 7.0 14.0 3.5 8.0 5.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Mpp10 PF04006.12 CEG43672.1 - 2.9e-142 475.2 57.4 4e-142 474.8 57.4 1.2 1 0 0 1 1 1 1 Mpp10 protein Pyridoxal_deC PF00282.19 CEG43673.1 - 1.7e-78 264.0 0.0 2.4e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PDZ PF00595.24 CEG43674.1 - 3e-20 72.3 0.1 0.00014 22.1 0.0 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 CEG43674.1 - 2.7e-14 52.7 0.1 0.15 11.9 0.0 5.4 5 0 0 5 5 5 5 PDZ domain zf-MYND PF01753.18 CEG43674.1 - 2.6e-06 27.4 8.8 4.7e-06 26.6 8.8 1.4 1 0 0 1 1 1 1 MYND finger PDZ_2 PF13180.6 CEG43674.1 - 6.2e-06 26.5 1.7 1.8 9.0 0.2 4.6 4 0 0 4 4 4 1 PDZ domain Merozoite_SPAM PF07133.11 CEG43674.1 - 1.4 8.9 20.6 2.8 7.9 20.6 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_photolyase PF00875.18 CEG43675.1 - 4.5e-12 46.3 0.7 1.1e-11 45.0 0.7 1.7 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 CEG43675.1 - 0.076 13.5 0.3 0.26 11.8 0.3 1.9 1 0 0 1 1 1 0 Universal stress protein family RRM_1 PF00076.22 CEG43679.1 - 6.7e-11 41.9 0.0 6.7e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 CEG43680.1 - 7.4e-103 344.0 0.5 1.4e-102 343.0 0.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG43680.1 - 2.2e-24 86.1 0.0 6.3e-22 78.1 0.0 3.6 2 1 0 2 2 2 1 Microtubule binding TSC22 PF01166.18 CEG43680.1 - 0.29 11.5 8.4 6.6 7.1 2.3 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family MscS_porin PF12795.7 CEG43680.1 - 0.46 10.0 38.7 2.1 7.8 14.1 3.8 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain PHM7_cyt PF14703.6 CEG43680.1 - 3.7 7.8 9.3 0.65 10.2 3.4 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter IF4E PF01652.18 CEG43683.1 - 1.1e-25 90.3 0.8 1.6e-25 89.7 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HEPN_DZIP3 PF18738.1 CEG43684.1 - 0.00025 20.8 0.3 0.00035 20.3 0.3 1.2 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN Patatin PF01734.22 CEG43684.1 - 0.012 15.9 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase CorA PF01544.18 CEG43684.1 - 0.015 14.7 1.5 0.019 14.3 1.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Trans_coact PF16805.5 CEG43684.1 - 0.052 13.6 1.3 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Phage late-transcription coactivator CPP1-like PF11833.8 CEG43684.1 - 0.37 10.4 3.3 1.3 8.6 1.4 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Phage_tail_2 PF06199.11 CEG43685.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube protein WD40 PF00400.32 CEG43686.1 - 5.4e-16 58.7 1.7 0.046 14.6 0.1 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43686.1 - 0.049 13.9 0.0 0.46 10.8 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain C2 PF00168.30 CEG43687.1 - 3.6e-19 69.0 0.0 5.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain ECH_1 PF00378.20 CEG43691.1 - 8.7e-65 218.5 0.0 1e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEG43691.1 - 6.8e-30 104.7 0.0 1.2e-27 97.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ribosomal_L15e PF00827.17 CEG43692.1 - 2.9e-90 301.1 8.1 3.3e-90 300.9 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 CEG43692.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain PP2C PF00481.21 CEG43694.1 - 7.9e-64 215.8 0.1 9.6e-64 215.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C LOB PF03195.14 CEG43694.1 - 0.025 15.2 0.0 0.56 10.8 0.0 2.7 3 0 0 3 3 3 0 Lateral organ boundaries (LOB) domain MiaE PF06175.11 CEG43695.1 - 0.021 14.4 0.4 0.038 13.6 0.4 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) PIP5K PF01504.18 CEG43696.1 - 3.8e-70 236.3 0.3 6.9e-70 235.4 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2070 PF09843.9 CEG43696.1 - 0.59 8.4 7.7 0.89 7.8 7.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_3_6 PF07332.11 CEG43696.1 - 1.3 9.1 13.9 16 5.6 0.0 2.8 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 CEG43699.1 - 3e-40 138.3 0.0 5.8e-40 137.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43699.1 - 3e-28 98.8 0.0 8.1e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG43699.1 - 3e-10 39.9 0.0 4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEG43699.1 - 4.8e-06 25.8 0.2 5.8e-06 25.5 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEG43699.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CEG43699.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG43699.1 - 0.0023 17.9 0.6 0.0037 17.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG43699.1 - 0.0075 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.19 CEG43699.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 Peptidase_S8 PF00082.22 CEG43700.1 - 7.1e-32 110.8 0.9 1e-31 110.4 0.9 1.2 1 0 0 1 1 1 1 Subtilase family 5_nucleotid_C PF02872.18 CEG43702.1 - 7.1e-28 97.8 0.0 1.5e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CEG43702.1 - 6.8e-10 39.8 0.0 1.1e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1180 PF06679.12 CEG43703.1 - 0.39 11.1 8.4 0.048 14.1 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 CEG43703.1 - 2.3 8.1 11.3 57 3.6 11.3 2.4 1 1 0 1 1 1 0 TMEM154 protein family Nse4_C PF08743.10 CEG43705.1 - 1.7e-20 73.0 0.1 5.8e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal TGase_elicitor PF16683.5 CEG43706.1 - 5.9e-144 479.3 1.8 7.4e-144 479.0 1.8 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor Herpes_capsid PF06112.11 CEG43706.1 - 0.1 12.7 9.7 0.21 11.7 9.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAM212 PF15342.6 CEG43707.1 - 1.6 8.6 3.9 2.4 8.0 1.3 2.1 2 0 0 2 2 2 0 FAM212 family ATP-gua_Ptrans PF00217.19 CEG43708.1 - 6.8e-77 257.7 0.0 8.9e-77 257.3 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CEG43708.1 - 5.2e-34 116.5 0.1 8.1e-29 99.8 0.0 2.3 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain AA_permease_2 PF13520.6 CEG43709.1 - 9.4e-36 123.5 32.7 5.9e-34 117.6 24.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CEG43709.1 - 2.1e-19 69.5 28.9 3.5e-19 68.7 28.1 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 CEG43709.1 - 2.7e-10 40.2 2.8 2.7e-10 40.2 2.8 3.5 3 0 0 3 3 3 1 C-terminus of AA_permease LPG_synthase_TM PF03706.13 CEG43709.1 - 0.00035 20.2 5.7 0.00035 20.2 5.7 3.1 1 1 1 3 3 3 1 Lysylphosphatidylglycerol synthase TM region Herpes_LMP1 PF05297.11 CEG43709.1 - 5.4 6.1 8.9 0.5 9.5 0.6 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) PEP-utilizers_C PF02896.18 CEG43710.1 - 0.01 14.9 0.0 0.012 14.7 0.0 1.0 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain AAA_23 PF13476.6 CEG43711.1 - 2.4e-27 96.8 20.5 2.4e-27 96.8 20.5 8.2 1 1 1 3 3 3 1 AAA domain AAA_21 PF13304.6 CEG43711.1 - 8.2e-09 35.7 1.0 0.0021 17.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG43711.1 - 4.9e-07 29.4 30.9 3.9e-06 26.5 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.14 CEG43711.1 - 0.0002 21.1 0.7 0.0002 21.1 0.7 4.5 4 0 0 4 4 4 1 Rad50 zinc hook motif SbcCD_C PF13558.6 CEG43711.1 - 0.0005 20.3 0.0 0.0017 18.6 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CEG43711.1 - 0.0011 18.8 25.6 0.0028 17.4 19.9 5.8 1 1 3 5 5 5 2 AAA ATPase domain AAA_25 PF13481.6 CEG43711.1 - 0.0045 16.6 0.7 0.033 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEG43711.1 - 0.14 12.7 0.0 0.14 12.7 0.0 6.2 3 2 0 4 4 4 0 ABC transporter AAA_16 PF13191.6 CEG43711.1 - 0.74 10.2 0.0 0.74 10.2 0.0 4.6 4 1 0 5 5 5 0 AAA ATPase domain TruD PF01142.18 CEG43712.1 - 1.1e-72 245.2 0.0 9e-70 235.6 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) YtxH PF12732.7 CEG43712.1 - 0.45 11.1 2.2 1.9 9.1 0.8 2.6 3 0 0 3 3 3 0 YtxH-like protein Lactamase_B PF00753.27 CEG43713.1 - 8.6e-13 48.7 0.1 2e-12 47.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEG43713.1 - 1.8e-08 34.2 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 CEG43713.1 - 0.00011 22.1 0.7 0.00018 21.4 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain PDEase_II PF02112.15 CEG43713.1 - 0.023 13.8 0.1 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Churchill PF06573.11 CEG43714.1 - 0.0024 18.2 3.3 0.0051 17.1 3.3 1.5 1 0 0 1 1 1 1 Churchill protein FYVE_2 PF02318.16 CEG43714.1 - 0.37 11.0 8.5 1 9.6 8.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 CEG43714.1 - 1.2 9.0 13.1 0.12 12.3 4.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 CEG43714.1 - 1.8 8.8 15.1 4.7 7.4 15.1 1.7 1 1 0 1 1 1 0 FYVE zinc finger Glyco_tran_28_C PF04101.16 CEG43716.1 - 6.7e-21 75.0 0.0 7.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UCH PF00443.29 CEG43719.1 - 1.4e-18 67.3 0.4 1.4e-18 67.3 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG43719.1 - 9.3e-09 35.3 0.4 2.3e-08 34.0 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CEG43719.1 - 8.3e-08 32.0 0.0 2.7e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain PDZ_6 PF17820.1 CEG43719.1 - 0.011 15.5 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Sulfatase PF00884.23 CEG43721.1 - 7.5e-37 127.4 0.1 9.9e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CEG43721.1 - 3.3e-05 23.6 0.0 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CEG43721.1 - 3.6e-05 22.6 0.0 0.0001 21.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 CEG43721.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF1218 PF06749.12 CEG43721.1 - 0.12 12.9 0.3 0.12 12.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Glyco_transf_20 PF00982.21 CEG43722.1 - 6.9e-111 371.2 0.0 9.8e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG43722.1 - 9.2e-33 113.3 0.0 3.3e-32 111.5 0.0 2.0 2 1 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.19 CEG43722.1 - 4.3e-08 33.0 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain DEAD PF00270.29 CEG43723.1 - 2.3e-47 161.0 0.0 4e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG43723.1 - 5.8e-08 33.1 0.1 7.3e-06 26.3 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG43723.1 - 2.2e-06 27.8 0.0 5.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ldh_1_C PF02866.18 CEG43723.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AAA_30 PF13604.6 CEG43723.1 - 0.0051 16.6 0.1 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain EF-hand_8 PF13833.6 CEG43723.1 - 0.027 14.3 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair La PF05383.17 CEG43727.1 - 1.9e-16 59.8 0.2 3.9e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 La domain PTS_2-RNA PF01885.16 CEG43727.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family TPR_19 PF14559.6 CEG43728.1 - 0.00013 22.4 9.0 4.8 7.8 0.1 5.1 4 1 0 4 4 4 3 Tetratricopeptide repeat RPN7 PF10602.9 CEG43728.1 - 0.001 18.8 0.3 0.0022 17.7 0.1 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 CEG43728.1 - 0.0027 17.7 0.5 21 5.6 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG43728.1 - 0.11 12.8 2.1 18 5.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43728.1 - 0.12 12.3 0.5 1.1 9.2 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ammonium_transp PF00909.21 CEG43729.1 - 1.7e-26 92.9 0.4 1.9e-26 92.7 0.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tachystatin_A PF11406.8 CEG43731.1 - 0.086 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A RabGAP-TBC PF00566.18 CEG43732.1 - 1.7e-09 37.6 2.2 1.7e-09 37.6 2.2 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 CEG43732.1 - 0.00033 21.4 0.0 28 5.8 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43732.1 - 0.01 16.1 0.0 2.4 8.5 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF745 PF05335.13 CEG43732.1 - 0.12 12.0 19.4 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) UCH PF00443.29 CEG43733.1 - 5.1e-73 245.7 0.0 8.2e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 CEG43733.1 - 1.7e-17 63.4 1.4 4.5e-17 62.0 1.4 1.7 1 0 0 1 1 1 1 PX domain UCH_1 PF13423.6 CEG43733.1 - 1.6e-15 57.6 0.4 4.9e-08 32.9 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEG43733.1 - 1.4e-14 54.5 0.3 4.6e-14 52.8 0.3 2.0 1 0 0 1 1 1 1 DUSP domain CFIA_Pcf11 PF11526.8 CEG43733.1 - 0.086 13.3 0.0 0.086 13.3 0.0 2.8 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 EF-hand_8 PF13833.6 CEG43733.1 - 0.093 12.6 1.3 0.74 9.7 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 CEG43733.1 - 0.11 12.5 0.9 2.6 8.2 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CEG43733.1 - 0.24 11.9 1.4 1.1 9.8 0.1 2.8 2 1 0 3 3 3 0 EF-hand domain pair PALP PF00291.25 CEG43735.1 - 1.7e-64 218.0 0.3 2e-64 217.8 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CTD_bind PF04818.13 CEG43736.1 - 2.1e-12 47.7 2.7 3e-12 47.2 0.0 2.6 3 1 1 4 4 4 1 RNA polymerase II-binding domain. Sec8_exocyst PF04048.14 CEG43736.1 - 0.02 14.8 4.2 0.12 12.2 1.7 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3546 PF12066.8 CEG43736.1 - 0.1 12.8 1.9 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) FAM167 PF11652.8 CEG43736.1 - 1 9.9 7.5 0.8 10.2 0.8 3.4 3 1 1 4 4 4 0 FAM167 NDUFB10 PF10249.9 CEG43737.1 - 0.0015 19.1 0.2 0.0017 18.8 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 TMF_DNA_bd PF12329.8 CEG43737.1 - 0.076 13.0 1.5 0.25 11.4 1.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding EutB PF06751.11 CEG43737.1 - 0.12 11.1 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) FANCA_interact PF15751.5 CEG43739.1 - 0.049 14.1 1.1 0.049 14.1 1.1 1.6 2 0 0 2 2 2 0 FAAP20 FANCA interaction domain CMAS PF02353.20 CEG43740.1 - 0.00015 21.1 0.1 0.051 12.8 0.2 2.0 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase WW PF00397.26 CEG43741.1 - 2e-36 123.8 33.4 1.6e-10 40.9 3.2 4.8 5 0 0 5 5 5 4 WW domain Glyco_hyd_101C PF17451.2 CEG43741.1 - 0.002 18.4 15.6 0.21 11.9 1.7 4.7 3 1 1 4 4 4 4 Glycosyl hydrolase 101 beta sandwich domain MCM_OB PF17207.3 CEG43741.1 - 0.25 11.2 1.6 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 MCM OB domain Glyco_hydro_52 PF03512.13 CEG43742.1 - 0.072 12.0 0.1 0.072 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 LRR_6 PF13516.6 CEG43743.1 - 9e-21 72.1 12.8 0.0019 18.1 0.0 8.3 8 0 0 8 8 8 6 Leucine Rich repeat LRR_8 PF13855.6 CEG43743.1 - 1.1e-06 28.3 3.5 0.012 15.4 0.2 5.2 4 3 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 CEG43743.1 - 2e-06 28.0 7.8 0.0039 17.6 0.1 5.9 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG43743.1 - 0.00012 22.1 0.0 52 5.0 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich Repeat NOA36 PF06524.12 CEG43743.1 - 0.34 10.2 5.5 0.55 9.5 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Hox9_act PF04617.13 CEG43744.1 - 3.7 8.3 10.4 5.1 7.8 9.1 1.9 1 1 0 1 1 1 0 Hox9 activation region RPN2_C PF18004.1 CEG43744.1 - 4.3 7.2 24.0 1.5 8.7 11.3 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain SNAP PF14938.6 CEG43745.1 - 1.3e-99 333.2 28.6 1.5e-99 333.0 28.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CEG43745.1 - 7.3e-08 32.6 10.8 0.028 14.7 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43745.1 - 7.4e-07 28.8 12.3 0.19 11.8 0.6 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43745.1 - 1.4e-06 27.9 17.3 0.0019 17.9 2.5 5.4 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43745.1 - 8.2e-06 25.6 20.7 0.00039 20.3 1.0 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG43745.1 - 1.2e-05 25.7 14.4 0.13 13.0 0.6 5.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43745.1 - 5.1e-05 23.8 8.4 0.0035 17.9 1.2 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG43745.1 - 0.00091 18.7 5.4 0.32 10.3 3.7 2.3 1 1 1 2 2 2 2 MalT-like TPR region RPN7 PF10602.9 CEG43745.1 - 0.0033 17.2 8.8 0.0076 16.0 3.0 3.2 1 1 2 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 CEG43745.1 - 0.0034 18.1 8.2 0.53 11.3 0.3 4.4 2 2 2 4 4 4 1 Tetratricopeptide repeat HHH_8 PF14716.6 CEG43745.1 - 0.0042 17.4 4.6 0.23 11.9 0.3 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain TPR_8 PF13181.6 CEG43745.1 - 0.0044 17.1 16.3 0.012 15.8 1.5 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Phage_term_smal PF05944.12 CEG43745.1 - 0.0069 16.4 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 Phage small terminase subunit MIT PF04212.18 CEG43745.1 - 0.03 14.4 17.7 0.19 11.8 3.1 4.3 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_1 PF12854.7 CEG43745.1 - 0.054 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 PPR repeat PPR PF01535.20 CEG43745.1 - 0.061 13.6 0.8 7.8 7.0 0.0 3.5 3 1 1 4 4 3 0 PPR repeat UDPG_MGDP_dh_C PF03720.15 CEG43745.1 - 0.083 13.3 0.2 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Foie-gras_1 PF11817.8 CEG43745.1 - 0.18 11.4 9.1 0.49 9.9 4.1 2.6 2 1 1 3 3 3 0 Foie gras liver health family 1 TPR_10 PF13374.6 CEG43745.1 - 0.34 10.8 14.5 6.4 6.8 1.6 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat HrpB2 PF09487.10 CEG43745.1 - 0.37 11.2 4.9 0.63 10.5 3.2 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) NSF PF02071.20 CEG43745.1 - 0.41 11.6 23.2 5.4 8.2 0.3 7.0 8 0 0 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat DUF2225 PF09986.9 CEG43745.1 - 0.44 10.2 13.6 0.023 14.4 4.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Y_phosphatase2 PF03162.13 CEG43746.1 - 3.5e-36 124.3 0.3 6.5e-36 123.4 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Serendipity_A PF05482.12 CEG43746.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) DUF4483 PF14825.6 CEG43750.1 - 0.00085 19.1 0.2 1.5 8.6 0.0 3.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4483) F5_F8_type_C PF00754.25 CEG43751.1 - 0.0001 22.5 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DICT PF10069.9 CEG43751.1 - 0.18 11.6 3.1 4.9 6.9 0.1 3.6 3 1 1 4 4 4 0 Sensory domain in DIguanylate Cyclases and Two-component system Wzz PF02706.15 CEG43752.1 - 0.01 16.1 2.0 3.2 8.1 1.2 2.3 2 0 0 2 2 2 0 Chain length determinant protein Picorna_P3A PF06363.11 CEG43752.1 - 0.014 15.3 2.2 0.021 14.7 1.8 1.5 2 0 0 2 2 2 0 Picornaviridae P3A protein CLASP_N PF12348.8 CEG43753.1 - 2.2e-07 30.7 1.4 6e-07 29.2 1.4 1.7 1 1 0 1 1 1 1 CLASP N terminal RAI16-like PF10257.9 CEG43753.1 - 0.011 14.6 2.6 0.15 10.9 0.6 2.1 1 1 1 2 2 2 0 Retinoic acid induced 16-like protein BACK PF07707.15 CEG43753.1 - 0.068 13.3 0.3 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch KRE1 PF17056.5 CEG43755.1 - 0.019 14.7 1.3 0.026 14.2 1.3 1.3 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 CoA_trans PF01144.23 CEG43756.1 - 4.8e-114 379.2 1.2 3.2e-72 242.4 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase RRM_1 PF00076.22 CEG43756.1 - 6e-15 54.8 0.0 1.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AcetylCoA_hyd_C PF13336.6 CEG43756.1 - 0.013 15.4 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain RWP-RK PF02042.15 CEG43758.1 - 0.0028 17.6 0.4 0.0057 16.6 0.4 1.6 1 0 0 1 1 1 1 RWP-RK domain TRPM_tetra PF16519.5 CEG43758.1 - 0.091 12.9 0.3 0.11 12.7 0.3 1.1 1 0 0 1 1 1 0 Tetramerisation domain of TRPM RVT_2 PF07727.14 CEG43760.1 - 2.2e-17 63.5 0.0 3.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RTTN_N PF14726.6 CEG43762.1 - 0.00079 20.2 5.4 0.001 19.8 1.4 3.6 3 0 0 3 3 3 1 Rotatin, an armadillo repeat protein, centriole functioning RNA_pol_N PF01194.17 CEG43762.1 - 0.099 13.0 0.1 0.57 10.5 0.1 2.4 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit RIH_assoc PF08454.11 CEG43762.1 - 1.3 8.9 8.3 4 7.4 1.8 4.4 4 0 0 4 4 4 0 RyR and IP3R Homology associated Peptidase_M50 PF02163.22 CEG43763.1 - 0.16 11.2 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 LCAT PF02450.15 CEG43764.1 - 0.0034 16.6 0.0 0.0035 16.6 0.0 1.3 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase MC1 PF05854.11 CEG43765.1 - 0.041 14.2 0.1 0.042 14.1 0.1 1.1 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 DRIM PF07539.12 CEG43767.1 - 2.9e-115 386.0 12.2 2.9e-115 386.0 12.2 5.1 5 1 1 6 6 6 3 Down-regulated in metastasis HEAT PF02985.22 CEG43767.1 - 1.7e-05 24.7 17.2 3.8 8.0 0.2 9.8 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CEG43767.1 - 0.021 15.4 2.0 22 5.7 0.0 5.7 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF5063 PF16702.5 CEG43767.1 - 0.11 12.9 3.3 2.5 8.5 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5063) Col_cuticle_N PF01484.17 CEG43767.1 - 0.16 12.0 0.6 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain IQ PF00612.27 CEG43768.1 - 2.2e-40 132.6 93.4 9.6e-05 21.8 0.0 17.2 17 0 0 17 17 17 15 IQ calmodulin-binding motif EF-hand_7 PF13499.6 CEG43768.1 - 1.2e-12 48.0 1.7 1.2e-12 48.0 1.7 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG43768.1 - 1.3e-12 46.3 0.2 5.2e-06 25.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CEG43768.1 - 1.8e-10 39.8 0.6 0.00047 19.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG43768.1 - 3e-09 36.1 0.1 0.0019 18.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 CEG43768.1 - 5.7e-09 35.9 15.7 2e-06 27.8 2.2 2.6 2 0 0 2 2 2 2 WW domain EF-hand_8 PF13833.6 CEG43768.1 - 3.5e-07 30.0 0.6 1.3e-06 28.2 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 CEG43768.1 - 0.0042 17.0 0.1 0.012 15.6 0.1 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TPR_2 PF07719.17 CEG43769.1 - 1.1e-33 112.6 26.9 1.1e-06 28.2 0.5 10.7 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43769.1 - 5.2e-31 105.2 22.6 1.6e-07 30.8 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG43769.1 - 7.1e-27 91.4 16.3 0.00026 20.9 0.1 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43769.1 - 1.6e-19 70.2 3.6 0.00054 20.4 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43769.1 - 4.5e-18 64.4 2.6 0.028 15.2 0.0 9.3 4 2 5 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43769.1 - 2.5e-16 60.0 1.4 6e-07 30.0 0.3 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43769.1 - 3.9e-16 58.4 12.5 5.9e-06 25.9 0.1 6.4 4 3 3 7 7 7 4 TPR repeat TPR_12 PF13424.6 CEG43769.1 - 1.9e-15 56.9 21.9 3.9e-11 43.1 0.2 6.9 7 2 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG43769.1 - 2.4e-15 56.5 25.8 1e-09 38.5 5.0 6.4 3 3 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CEG43769.1 - 5e-14 51.6 7.3 0.0018 18.5 0.0 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43769.1 - 5.6e-12 44.8 11.6 0.024 14.7 0.1 5.4 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG43769.1 - 5.7e-08 32.4 9.7 0.024 14.5 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG43769.1 - 9.1e-08 32.1 0.0 0.0023 18.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG43769.1 - 1.2e-06 28.7 21.1 0.13 12.9 0.3 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG43769.1 - 9.2e-06 25.1 1.9 0.23 10.6 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat DUF4919 PF16266.5 CEG43769.1 - 0.00045 20.2 0.3 0.054 13.4 0.0 2.9 3 1 0 3 3 2 1 Domain of unknown function (DUF4919) TPR_MalT PF17874.1 CEG43769.1 - 0.00095 18.6 0.7 4 6.7 0.1 4.0 2 1 0 3 3 3 1 MalT-like TPR region TPR_3 PF07720.12 CEG43769.1 - 0.0025 17.8 0.4 0.0025 17.8 0.4 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF4810 PF16068.5 CEG43769.1 - 0.034 14.7 0.4 15 6.2 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) Rapsyn_N PF10579.9 CEG43769.1 - 0.043 13.9 0.2 5.9 7.1 0.0 3.6 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Sel1 PF08238.12 CEG43769.1 - 0.25 12.1 8.2 24 5.8 0.1 4.6 4 0 0 4 4 4 0 Sel1 repeat Fis1_TPR_C PF14853.6 CEG43769.1 - 0.5 10.5 7.5 0.14 12.3 0.3 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 CEG43769.1 - 2.1 7.8 6.1 20 4.6 0.1 3.5 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like Myosin_head PF00063.21 CEG43770.1 - 2.8e-192 640.6 0.1 1.2e-152 509.6 0.1 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) FYVE PF01363.21 CEG43770.1 - 9.4e-17 60.9 6.9 3e-16 59.3 6.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 CEG43770.1 - 3.1e-06 26.5 30.0 0.056 13.2 2.2 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CEG43770.1 - 0.0079 16.5 0.2 0.068 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEG43770.1 - 0.02 13.9 0.4 0.094 11.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 CEG43770.1 - 0.029 14.8 1.5 0.1 13.0 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain zf-AN1 PF01428.16 CEG43770.1 - 4.6 7.5 9.3 15 5.8 9.3 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger DUF4679 PF15728.5 CEG43771.1 - 0.14 11.1 5.1 0.16 11.0 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) RRM_1 PF00076.22 CEG43774.1 - 1e-07 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG43774.1 - 0.00035 20.5 0.1 0.00059 19.8 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CEG43774.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEG43774.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 CEG43774.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Zip PF02535.22 CEG43775.1 - 2.8e-07 30.1 9.7 9.2e-07 28.4 7.4 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter ADH_zinc_N_2 PF13602.6 CEG43777.1 - 3.5e-14 54.0 0.1 5.5e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEG43777.1 - 2.2e-11 43.9 0.2 3.5e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NTP_transf_3 PF12804.7 CEG43778.1 - 2.8e-08 34.3 0.1 6.4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain EamA PF00892.20 CEG43778.1 - 7.7e-08 32.6 33.0 8.2e-05 22.8 10.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family NTP_transferase PF00483.23 CEG43778.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Cys_Met_Meta_PP PF01053.20 CEG43780.1 - 3.3e-37 127.9 0.6 3.8e-37 127.7 0.6 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CEG43780.1 - 0.00014 20.6 0.0 0.00016 20.3 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CEG43780.1 - 0.038 13.2 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Kelch_3 PF13415.6 CEG43782.1 - 5.5e-40 134.9 12.9 3.1e-09 36.9 0.1 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG43782.1 - 7.5e-33 111.9 16.3 8.8e-10 38.0 0.2 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CEG43782.1 - 5e-31 106.5 12.1 2.9e-07 30.4 0.1 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG43782.1 - 1.1e-29 101.7 18.1 9.4e-07 28.9 0.2 6.7 6 1 1 7 7 7 5 Kelch motif Kelch_5 PF13854.6 CEG43782.1 - 2e-23 81.9 22.8 3.3e-06 26.9 0.6 7.1 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 CEG43782.1 - 6e-20 70.4 12.9 0.00058 19.7 0.9 6.5 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 CEG43782.1 - 3.4e-05 23.0 3.1 0.028 13.4 0.1 4.4 4 2 0 4 4 4 1 Recombination activating protein 2 UBA2_C PF16195.5 CEG43787.1 - 0.11 13.2 0.6 0.11 13.2 0.6 1.7 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus FAD_binding_1 PF00667.20 CEG43789.1 - 7.5e-22 78.0 0.2 1.6e-21 76.9 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CEG43789.1 - 3.9e-16 59.7 0.0 1.1e-15 58.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEG43789.1 - 0.022 14.9 0.0 0.12 12.5 0.0 2.1 3 0 0 3 3 3 0 Ferric reductase NAD binding domain ArsC PF03960.15 CEG43789.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 ArsC family GST_N_3 PF13417.6 CEG43792.1 - 3.4e-14 53.0 0.0 8.5e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEG43792.1 - 1.6e-12 47.6 0.0 3.9e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEG43792.1 - 2.5e-08 34.0 0.1 3.9e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CEG43792.1 - 1.3e-07 31.8 0.0 3.7e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEG43792.1 - 1.3e-05 25.3 0.1 3.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1495 PF07381.11 CEG43792.1 - 0.0021 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) GST_C_2 PF13410.6 CEG43792.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FHA PF00498.26 CEG43793.1 - 6.5e-17 61.7 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG43793.1 - 1.4e-05 25.4 0.1 0.00012 22.3 0.1 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GrpB PF04229.14 CEG43793.1 - 0.035 14.3 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 GrpB protein Vac7 PF12751.7 CEG43793.1 - 6.3 6.1 10.6 6.2 6.1 9.7 1.3 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Ribosomal_L7Ae PF01248.26 CEG43794.1 - 3.4e-26 90.8 0.0 4.7e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CEG43794.1 - 4.6e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CEG43794.1 - 0.004 17.2 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 TPR_1 PF00515.28 CEG43795.1 - 1.5e-35 119.6 22.6 0.002 17.9 0.0 12.6 13 0 0 13 13 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43795.1 - 9.4e-31 103.4 21.8 0.00045 20.1 0.0 12.4 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43795.1 - 2.9e-29 100.5 5.2 0.00074 19.1 0.0 10.6 9 2 2 11 11 11 6 TPR repeat TPR_17 PF13431.6 CEG43795.1 - 1e-21 75.7 0.4 0.00027 21.1 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG43795.1 - 7e-18 63.3 20.8 0.074 13.3 0.3 11.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43795.1 - 5.4e-16 59.0 1.2 0.013 16.2 0.0 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43795.1 - 1.1e-15 56.5 6.1 0.004 17.1 0.0 9.2 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43795.1 - 1.2e-15 56.8 5.6 0.0081 16.9 0.0 9.7 7 3 3 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43795.1 - 2.3e-14 53.6 5.7 0.025 15.1 0.3 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEG43795.1 - 8.6e-14 51.6 14.9 0.048 14.0 0.0 7.6 6 4 1 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 CEG43795.1 - 1.3e-11 44.4 0.1 0.00092 19.3 0.0 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG43795.1 - 1e-08 34.8 12.3 0.032 14.1 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG43795.1 - 0.0017 18.5 11.2 0.21 11.8 0.5 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 CEG43795.1 - 0.022 14.7 4.2 1.7 8.7 0.2 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.12 CEG43795.1 - 0.028 15.1 0.7 0.95 10.2 0.1 3.5 3 0 0 3 3 2 0 Sel1 repeat Ada3 PF10198.9 CEG43795.1 - 0.036 14.2 0.1 0.036 14.2 0.1 3.0 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 MAS20 PF02064.15 CEG43795.1 - 0.049 13.7 15.6 0.53 10.4 0.9 5.3 4 2 1 5 5 4 0 MAS20 protein import receptor DUF3856 PF12968.7 CEG43795.1 - 0.081 13.0 5.9 8.6 6.4 0.1 4.6 4 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) DUF4578 PF15147.6 CEG43795.1 - 0.13 13.1 4.3 0.34 11.8 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Fis1_TPR_C PF14853.6 CEG43795.1 - 0.2 11.7 3.7 30 4.8 0.0 4.7 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CEG43795.1 - 0.28 11.3 15.2 0.91 9.6 0.8 6.2 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CEG43795.1 - 0.47 11.2 13.7 96 3.9 0.1 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEG43795.1 - 0.69 9.6 14.1 3 7.5 0.2 4.9 3 2 4 7 7 7 0 Tetratricopeptide repeat-like domain G6PD_N PF00479.22 CEG43796.1 - 0.0085 16.7 2.0 0.015 15.9 1.2 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IMP2_N PF18590.1 CEG43796.1 - 0.089 13.4 0.9 0.66 10.6 0.8 2.6 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) N-terminal domain DUF1140 PF06600.11 CEG43796.1 - 0.17 12.4 3.2 0.44 11.0 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) SGL PF08450.12 CEG43797.1 - 3.5e-13 49.7 0.3 8.8e-13 48.4 0.3 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region MMR_HSR1_C PF08438.10 CEG43798.1 - 5e-30 104.4 0.0 9.1e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CEG43798.1 - 4.6e-20 71.8 0.0 1.7e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG43798.1 - 1.2e-09 37.8 0.4 1.4e-08 34.4 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 CEG43798.1 - 0.0042 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain GTP_EFTU PF00009.27 CEG43798.1 - 0.0062 16.1 0.0 0.065 12.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CEG43798.1 - 0.096 12.7 0.3 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Voltage_CLC PF00654.20 CEG43799.1 - 2.2e-72 244.2 33.0 2.2e-72 244.2 33.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CEG43799.1 - 1.8e-05 25.1 0.3 0.19 12.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain S1FA PF04689.13 CEG43799.1 - 0.72 10.0 1.9 1.3 9.2 0.9 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA Mur_ligase_M PF08245.12 CEG43800.1 - 0.4 10.7 3.5 0.3 11.1 0.9 2.2 2 0 0 2 2 2 0 Mur ligase middle domain BRX PF08381.11 CEG43801.1 - 0.00096 18.5 0.3 0.00096 18.5 0.3 2.2 2 0 0 2 2 2 1 Transcription factor regulating root and shoot growth via Pin3 GPS2_interact PF15784.5 CEG43801.1 - 0.3 11.6 3.1 0.98 9.9 1.1 2.6 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Jacalin PF01419.17 CEG43802.1 - 1.6e-09 37.8 0.3 3.9e-09 36.5 0.3 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain TT1725 PF18324.1 CEG43802.1 - 0.14 12.2 1.6 9.3 6.4 0.0 3.3 2 0 0 2 2 2 0 Hypothetical protein TT1725 EMC3_TMCO1 PF01956.16 CEG43803.1 - 2.5e-33 115.2 27.2 2e-25 89.5 19.1 2.3 1 1 1 2 2 2 2 Integral membrane protein EMC3/TMCO1-like zf-CDGSH PF09360.10 CEG43803.1 - 1.7e-11 44.1 1.6 3.8e-11 43.0 1.6 1.6 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type FYVE PF01363.21 CEG43804.1 - 5.3e-12 45.7 7.0 1.4e-11 44.4 7.0 1.8 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG43804.1 - 0.014 15.6 3.4 0.014 15.6 3.4 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 CEG43804.1 - 0.26 11.5 5.7 1 9.5 5.7 2.0 1 0 0 1 1 1 0 B-box zinc finger FYVE PF01363.21 CEG43805.1 - 2.4e-13 50.0 7.6 5.5e-13 48.9 7.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger TPR_1 PF00515.28 CEG43806.1 - 2.5e-24 84.0 20.1 5.7e-06 25.9 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG43806.1 - 4.5e-24 82.6 14.4 3.2e-05 23.8 0.0 8.5 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43806.1 - 2.3e-21 74.1 28.3 0.0002 21.2 0.0 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43806.1 - 3.5e-17 62.8 11.0 2.4e-05 24.9 0.6 6.5 4 2 1 5 5 5 3 Tetratricopeptide repeat ANAPC8 PF04049.13 CEG43806.1 - 1.1e-16 61.2 0.5 2.9e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 CEG43806.1 - 1.2e-15 56.9 18.0 0.042 14.7 0.2 9.3 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43806.1 - 5.1e-12 46.1 12.2 0.13 12.8 1.9 6.8 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43806.1 - 2.3e-11 42.9 6.8 0.073 13.1 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43806.1 - 3.1e-11 42.7 8.5 2.4e-06 27.1 1.2 5.6 4 2 2 6 6 6 3 TPR repeat TPR_12 PF13424.6 CEG43806.1 - 3.3e-11 43.3 19.0 4.2e-06 27.0 0.5 6.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG43806.1 - 5.6e-07 29.8 15.5 3.4 8.5 0.1 8.3 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG43806.1 - 2.6e-06 27.5 14.2 0.044 13.9 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG43806.1 - 3.6e-05 23.7 0.1 0.18 11.9 0.0 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CEG43806.1 - 5.5e-05 23.3 16.4 0.21 11.8 0.2 6.4 4 1 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 CEG43806.1 - 5.5e-05 22.3 0.1 0.0066 15.5 0.0 2.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 CEG43806.1 - 0.0001 22.4 17.2 1.7 9.2 0.0 7.5 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEG43806.1 - 0.00087 18.6 4.6 0.061 12.5 0.2 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG43806.1 - 0.097 12.6 11.3 8.3 6.4 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 CEG43806.1 - 0.11 12.9 3.1 4.8 7.6 0.1 3.8 2 2 1 3 3 3 0 Bacterial transcriptional activator domain PPR PF01535.20 CEG43806.1 - 0.26 11.6 1.9 3.7 8.0 0.0 3.3 4 0 0 4 4 2 0 PPR repeat LRR_6 PF13516.6 CEG43807.1 - 0.051 13.6 0.3 9.4 6.6 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CEG43807.1 - 0.34 11.6 2.0 50 5.0 0.2 3.8 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 CEG43807.1 - 4.4 7.9 9.5 0.77 10.3 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) zf-CCCH PF00642.24 CEG43810.1 - 0.00023 21.0 5.0 0.0005 19.9 5.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG43810.1 - 0.0017 18.1 4.8 0.0029 17.4 4.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 CEG43810.1 - 0.0033 17.4 0.8 0.0033 17.4 0.8 2.7 3 0 0 3 3 3 1 TFIIS helical bundle-like domain tRNA_synthFbeta PF17759.1 CEG43810.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain zf_CCCH_4 PF18345.1 CEG43810.1 - 0.23 11.6 5.7 0.51 10.5 5.7 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CEG43810.1 - 1.2 9.8 6.0 2.4 8.8 6.0 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF2753 PF10952.8 CEG43811.1 - 0.013 15.6 0.2 0.014 15.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Ribosomal_S6e PF01092.19 CEG43812.1 - 3.9e-58 194.9 0.1 7.8e-58 193.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cyto_heme_lyase PF01265.17 CEG43813.1 - 3.8e-53 181.0 5.4 8.3e-52 176.6 5.4 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GOLGA2L5 PF15070.6 CEG43813.1 - 0.069 11.8 0.5 0.098 11.3 0.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Chromo PF00385.24 CEG43815.1 - 4.5e-08 32.9 1.1 1.1e-07 31.7 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 CEG43815.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 PWWP domain Chromo_shadow PF01393.19 CEG43815.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain UPF0203 PF05254.12 CEG43819.1 - 1.3e-08 34.9 6.1 1.3e-08 34.9 6.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0203) Ank_5 PF13857.6 CEG43819.1 - 0.00024 21.3 0.1 0.00071 19.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Mvb12 PF09452.10 CEG43819.1 - 0.081 13.4 0.4 0.081 13.4 0.4 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Arylesterase PF01731.20 CEG43820.1 - 0.16 12.2 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 Arylesterase Feld-I_B PF09252.10 CEG43821.1 - 0.023 14.7 0.0 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 Allergen Fel d I-B chain PRP38 PF03371.15 CEG43823.1 - 1.3e-55 188.0 0.4 1.4e-55 187.8 0.4 1.0 1 0 0 1 1 1 1 PRP38 family AKAP7_NLS PF10469.9 CEG43823.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain zf-RING_2 PF13639.6 CEG43824.1 - 6e-10 39.3 12.3 1.2e-09 38.3 12.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG43824.1 - 4.1e-08 33.4 10.0 1.1e-07 32.0 10.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEG43824.1 - 3e-05 23.9 7.9 6.2e-05 22.9 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CEG43824.1 - 6.8e-05 22.5 6.9 0.00012 21.7 6.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEG43824.1 - 0.00016 21.4 9.6 0.00038 20.3 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG43824.1 - 0.0002 21.1 12.6 0.00035 20.4 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG43824.1 - 0.00061 19.6 13.0 0.0013 18.6 13.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG43824.1 - 0.00062 19.7 10.2 0.0012 18.7 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CEG43824.1 - 0.00082 18.9 7.8 0.0014 18.2 7.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 CEG43824.1 - 0.0077 16.5 2.8 0.017 15.4 2.8 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 CEG43824.1 - 0.026 14.4 8.4 0.054 13.4 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_15 PF17032.5 CEG43824.1 - 0.033 14.9 1.6 0.076 13.8 1.6 1.6 1 0 0 1 1 1 0 zinc-ribbon family FANCL_C PF11793.8 CEG43824.1 - 0.046 13.9 4.6 0.8 9.9 6.7 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CEG43824.1 - 0.051 13.6 7.3 0.17 12.0 7.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 CEG43824.1 - 0.072 13.3 2.7 0.14 12.4 2.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 CEG43824.1 - 0.072 13.4 9.9 0.12 12.7 9.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 CEG43824.1 - 0.28 11.2 2.5 0.56 10.3 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CEG43824.1 - 0.62 10.2 11.0 1.2 9.3 11.0 1.4 1 0 0 1 1 1 0 RING-variant domain PX PF00787.24 CEG43825.1 - 3e-09 36.8 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PX domain Exo_endo_phos PF03372.23 CEG43825.1 - 0.0032 17.0 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ser_hydrolase PF06821.13 CEG43826.1 - 0.046 13.6 0.0 0.051 13.4 0.0 1.0 1 0 0 1 1 1 0 Serine hydrolase MCM PF00493.23 CEG43827.1 - 2.7e-76 255.6 0.3 3.9e-76 255.1 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CEG43827.1 - 1.9e-25 89.1 0.2 4.6e-25 87.8 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CEG43827.1 - 6.9e-23 80.9 1.2 1.3e-22 80.0 1.2 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CEG43827.1 - 1.4e-08 34.4 0.2 4.7e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEG43827.1 - 2.2e-08 34.2 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEG43827.1 - 0.00013 21.7 0.1 0.0013 18.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CEG43827.1 - 0.00026 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG43827.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 CEG43827.1 - 0.021 14.2 0.4 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 CEG43827.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG43827.1 - 0.073 13.4 0.1 0.31 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CEG43827.1 - 0.096 12.8 0.1 0.36 10.9 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CEG43827.1 - 0.12 12.6 0.1 1.5 9.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEG43827.1 - 0.21 11.5 0.5 9.6 6.1 0.1 2.4 1 1 0 2 2 2 0 NTPase Lyase_1 PF00206.20 CEG43829.1 - 5.5e-87 292.1 0.0 7.2e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CEG43829.1 - 3.5e-24 85.3 0.4 1e-23 83.9 0.2 1.9 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Ribosomal_S21 PF01165.20 CEG43830.1 - 1.7e-07 30.8 3.2 3e-07 30.0 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Ysc84 PF04366.12 CEG43832.1 - 1e-39 135.2 0.0 1.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 CEG43832.1 - 4.9e-19 68.2 6.2 7.6e-19 67.6 6.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_9 PF13901.6 CEG43832.1 - 0.0016 18.5 0.8 0.0025 17.8 0.8 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-CRD PF17979.1 CEG43832.1 - 1.6 8.8 8.1 3.8 7.6 8.1 1.5 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 CEG43832.1 - 6.8 6.6 9.3 39 4.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med7 PF05983.11 CEG43833.1 - 2.4e-43 148.5 4.8 2.7e-41 141.8 4.8 2.2 1 1 0 1 1 1 1 MED7 protein V-SNARE PF05008.15 CEG43833.1 - 0.044 14.2 0.5 0.12 12.8 0.5 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF3161 PF11362.8 CEG43833.1 - 0.087 12.8 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) Lum_binding PF00677.17 CEG43833.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Lumazine binding domain Mpv17_PMP22 PF04117.12 CEG43834.1 - 8e-25 86.8 2.2 4.6e-24 84.4 1.3 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Tad PF13400.6 CEG43835.1 - 0.65 10.4 3.8 1.5 9.2 3.8 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like GAS PF13851.6 CEG43835.1 - 2.1 7.6 37.4 0.25 10.7 15.0 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CEG43835.1 - 8.1 6.8 14.5 0.61 10.3 0.3 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 CEG43835.1 - 8.3 6.4 36.6 0.21 11.6 6.6 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HA PF03457.14 CEG43836.1 - 1.3e-20 73.5 0.2 4.9e-07 30.0 0.0 5.0 5 0 0 5 5 5 3 Helicase associated domain Peptidase_M29 PF02073.15 CEG43836.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Abhydrolase_1 PF00561.20 CEG43838.1 - 0.0018 17.9 0.4 0.0048 16.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_1 PF00232.18 CEG43839.1 - 4.8e-72 242.8 0.1 6.4e-72 242.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 CEG43839.1 - 0.0098 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Phenol_hyd_sub PF06099.11 CEG43839.1 - 0.11 12.6 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Phenol hydroxylase subunit Glyco_hydro_1 PF00232.18 CEG43840.1 - 3.3e-126 421.4 0.1 4e-126 421.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3218 PF11508.8 CEG43840.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) DEAD PF00270.29 CEG43842.1 - 2.8e-50 170.5 0.0 9.2e-50 168.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG43842.1 - 8.2e-35 119.5 0.0 2.8e-30 104.9 0.0 3.4 1 1 2 3 3 3 2 Helicase conserved C-terminal domain CMS1 PF14617.6 CEG43842.1 - 0.02 14.3 0.0 0.02 14.3 0.0 3.9 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_11 PF13086.6 CEG43842.1 - 0.26 11.1 13.3 13 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain SOBP PF15279.6 CEG43842.1 - 4.4 7.8 9.1 7.2 7.1 9.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GEMIN8 PF15348.6 CEG43842.1 - 5 7.3 16.9 8.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 WD40_4 PF16300.5 CEG43844.1 - 1.4e-27 95.3 3.4 3.6e-15 55.6 0.0 3.1 3 0 0 3 3 3 2 Type of WD40 repeat WD40 PF00400.32 CEG43844.1 - 1.3e-16 60.7 9.3 0.0024 18.6 0.0 8.0 9 0 0 9 9 9 3 WD domain, G-beta repeat DUF1899 PF08953.11 CEG43844.1 - 1e-11 44.5 0.5 2.5e-05 24.0 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 CEG43844.1 - 5.6e-05 23.4 0.2 3.5 8.0 0.1 5.1 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEG43844.1 - 0.067 11.2 0.0 0.21 9.5 0.0 1.7 2 0 0 2 2 2 0 IKI3 family PPR_2 PF13041.6 CEG43845.1 - 4e-11 42.9 8.3 3.1e-05 24.1 0.0 6.8 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.20 CEG43845.1 - 1.1e-07 31.6 2.8 1.3 9.4 0.0 6.1 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 CEG43845.1 - 8.3e-06 25.3 0.2 0.85 8.9 0.0 3.8 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CEG43845.1 - 7.3e-05 22.8 5.6 0.033 14.3 0.0 5.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain TPR_2 PF07719.17 CEG43846.1 - 5.9e-28 94.7 7.7 0.076 13.2 0.2 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43846.1 - 3.3e-24 83.6 9.5 4.1e-05 23.2 0.0 8.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 CEG43846.1 - 9.8e-19 67.4 7.1 0.0065 16.7 0.1 7.6 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG43846.1 - 4.8e-17 60.7 3.1 0.0092 16.1 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43846.1 - 2.2e-13 49.8 5.3 0.31 12.0 0.0 8.4 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43846.1 - 3.2e-12 46.9 4.6 0.12 13.0 0.0 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG43846.1 - 1.7e-09 37.6 0.6 0.21 11.8 0.0 5.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG43846.1 - 2.3e-09 37.0 4.8 0.0016 18.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG43846.1 - 6.6e-08 32.9 5.9 0.0072 16.8 0.1 5.3 3 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43846.1 - 4.8e-07 29.4 7.5 0.92 9.7 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG43846.1 - 8.6e-07 28.5 9.1 0.048 13.4 0.1 5.7 7 1 0 7 7 7 2 TPR repeat TPR_6 PF13174.6 CEG43846.1 - 4.3e-06 27.0 1.6 30 5.5 0.1 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 CEG43846.1 - 0.0059 15.8 4.4 0.98 8.6 3.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG43846.1 - 0.02 15.1 10.9 0.89 9.8 0.5 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEG43846.1 - 0.02 14.7 7.2 2.5 8.1 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG43846.1 - 0.028 14.5 2.6 1.2 9.2 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat PTEN_C2 PF10409.9 CEG43846.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Metallophos PF00149.28 CEG43847.1 - 2.4e-34 119.6 0.1 3.2e-34 119.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEG43847.1 - 0.002 18.5 0.1 0.0042 17.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DSPc PF00782.20 CEG43851.1 - 1.5e-23 83.1 0.0 2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CEG43851.1 - 0.0013 19.0 0.1 0.0026 18.0 0.1 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 CEG43851.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase 2-Hacid_dh_C PF02826.19 CEG43852.1 - 3.2e-56 189.5 0.0 4.4e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEG43852.1 - 3.6e-26 91.4 0.0 4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CEG43852.1 - 1.6e-05 25.2 0.0 4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CEG43852.1 - 0.00088 19.4 0.2 0.0059 16.7 0.0 2.3 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 CEG43852.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CEG43852.1 - 0.0051 16.4 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 CEG43852.1 - 0.029 13.9 0.3 0.062 12.9 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CEG43852.1 - 0.1 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CEG43852.1 - 0.17 11.9 0.8 0.57 10.2 0.2 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_syn_central PF04898.14 CEG43855.1 - 0.0049 16.4 0.4 0.054 13.0 0.2 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain SOGA PF11365.8 CEG43855.1 - 0.09 13.9 2.5 0.17 13.0 2.5 1.4 1 0 0 1 1 1 0 Protein SOGA CCDC-167 PF15188.6 CEG43855.1 - 1.5 9.2 5.0 0.27 11.6 0.2 2.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 CCDC-167 PF15188.6 CEG43857.1 - 0.041 14.2 0.8 0.63 10.4 0.3 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 OmpH PF03938.14 CEG43857.1 - 0.13 12.6 0.3 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 CEG43857.1 - 0.2 12.0 2.3 0.28 11.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4819 PF16090.5 CEG43860.1 - 0.024 14.7 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) MIT PF04212.18 CEG43861.1 - 0.0053 16.8 1.8 0.0053 16.8 1.8 3.0 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain DUF325 PF03804.13 CEG43861.1 - 0.075 13.1 0.3 0.79 9.8 0.0 2.8 3 0 0 3 3 3 0 Viral proteins of unknown function DUF4094 PF13334.6 CEG43861.1 - 2.9 8.4 9.6 3.4 8.2 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) Choline_kin_N PF04428.14 CEG43862.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline kinase N terminus Yqai PF09466.10 CEG43863.1 - 0.16 12.3 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical protein Yqai Rubella_E2 PF05749.11 CEG43864.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 MFS_1 PF07690.16 CEG43869.1 - 6.7e-25 87.8 53.2 6.2e-18 64.8 30.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SKG6 PF08693.10 CEG43870.1 - 0.0014 18.0 0.8 0.0025 17.2 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 CEG43870.1 - 0.072 14.0 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 CEG43870.1 - 0.16 12.4 0.0 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT FHA PF00498.26 CEG43874.1 - 2.9e-10 40.3 0.1 6.3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain DUF148 PF02520.17 CEG43874.1 - 0.0086 16.2 6.6 0.0086 16.2 6.6 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF148 UPF0147 PF03685.13 CEG43874.1 - 0.041 13.9 5.5 0.1 12.7 0.0 3.4 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0147) Rad60-SLD PF11976.8 CEG43875.1 - 9.8e-27 92.6 0.5 4.3e-08 32.9 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEG43875.1 - 9.3e-17 60.6 0.7 4e-05 23.3 0.1 3.6 3 0 0 3 3 3 3 Ubiquitin family DUF4297 PF14130.6 CEG43875.1 - 0.012 15.8 1.1 0.012 15.8 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4297) Ubiquitin_5 PF18037.1 CEG43875.1 - 0.061 13.7 7.5 0.87 10.0 0.1 4.2 5 1 0 5 5 5 0 Ubiquitin-like domain FAM219A PF15260.6 CEG43875.1 - 0.2 12.0 11.6 0.36 11.2 3.4 2.6 1 1 1 2 2 2 0 Protein family FAM219A Pal1 PF08316.11 CEG43875.1 - 0.43 11.3 2.3 23 5.7 0.8 2.5 2 1 1 3 3 3 0 Pal1 cell morphology protein Cwf_Cwc_15 PF04889.12 CEG43875.1 - 2.8 7.6 22.4 0.62 9.8 18.0 1.9 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PNISR PF15996.5 CEG43875.1 - 5.1 7.3 16.1 7.3 6.8 14.6 1.8 1 1 1 2 2 2 0 Arginine/serine-rich protein PNISR RRM_1 PF00076.22 CEG43876.1 - 6.2e-30 102.8 0.0 1.8e-14 53.3 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG43876.1 - 7.6e-05 22.8 0.0 0.0028 17.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif DUF1866 PF08952.11 CEG43876.1 - 0.037 13.9 0.0 4.6 7.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) GST_C_3 PF14497.6 CEG43877.1 - 1.8e-06 28.0 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEG43877.1 - 1.7e-05 25.0 0.1 3.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEG43877.1 - 7.6e-05 22.7 0.4 0.00014 21.8 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CEG43877.1 - 0.0012 18.6 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Kelch_5 PF13854.6 CEG43878.1 - 1.3e-28 98.4 6.4 4.2e-06 26.6 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CEG43878.1 - 3.3e-26 91.0 5.4 9.7e-08 31.9 0.0 5.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEG43878.1 - 5e-23 80.9 9.7 5.8e-07 29.6 0.0 7.5 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG43878.1 - 1.1e-22 79.5 4.8 8.7e-05 22.7 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 CEG43878.1 - 1.6e-17 62.8 7.6 2.7e-07 30.0 0.1 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEG43878.1 - 1e-16 60.2 15.9 0.00084 19.2 1.1 6.6 7 1 0 7 7 7 4 Kelch motif RAG2 PF03089.14 CEG43878.1 - 2.8e-06 26.5 0.0 0.27 10.2 0.0 4.5 5 0 0 5 5 5 3 Recombination activating protein 2 tRNA-synt_2b PF00587.25 CEG43879.1 - 9.1e-36 123.5 0.0 1.5e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEG43879.1 - 1.3e-17 63.8 0.2 2.2e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CEG43879.1 - 6.5e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CxxCxxCC PF03692.15 CEG43880.1 - 2e-12 47.6 4.9 4.4e-12 46.5 3.9 2.0 2 0 0 2 2 2 1 Putative zinc- or iron-chelating domain MMgT PF10270.9 CEG43881.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Membrane magnesium transporter MORN PF02493.20 CEG43882.1 - 2.2e-18 65.0 18.3 7.5e-05 22.4 0.5 7.7 8 0 0 8 8 8 5 MORN repeat Cwf_Cwc_15 PF04889.12 CEG43883.1 - 4.5e-69 232.9 23.5 5.1e-69 232.7 23.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CEG43883.1 - 0.15 10.3 16.7 0.16 10.2 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein rRNA_processing PF08524.11 CEG43883.1 - 6.7 6.7 26.4 0.061 13.4 12.8 2.1 1 1 1 2 2 2 0 rRNA processing DUF1624 PF07786.12 CEG43884.1 - 0.052 13.1 7.1 0.057 13.0 6.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1624) Pept_tRNA_hydro PF01195.19 CEG43885.1 - 4.3e-45 153.7 0.0 1.8e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase DAHP_synth_1 PF00793.20 CEG43886.1 - 5.7e-54 182.8 0.0 7.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family cNMP_binding PF00027.29 CEG43887.1 - 5.2e-13 48.9 0.1 3.1e-09 36.8 0.1 3.8 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain PH PF00169.29 CEG43889.1 - 6e-09 36.4 0.2 8.2e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG43889.1 - 0.16 12.4 1.1 0.25 11.8 1.1 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain eIF3_p135 PF12807.7 CEG43890.1 - 1.9e-12 47.6 0.0 4.3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CEG43890.1 - 5.5e-06 26.6 1.3 0.16 12.3 0.0 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat CLU PF13236.6 CEG43890.1 - 2e-05 24.6 0.0 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria TPR_8 PF13181.6 CEG43890.1 - 0.0021 18.1 1.9 13 6.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5630 PF18632.1 CEG43890.1 - 0.0084 15.4 1.4 0.17 11.2 0.1 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5630) TPR_10 PF13374.6 CEG43890.1 - 0.012 15.5 2.2 41 4.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG43890.1 - 0.036 14.1 0.3 6.8 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG43890.1 - 0.04 14.8 0.2 60 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG43890.1 - 0.12 12.2 2.8 3.2 7.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG43890.1 - 0.17 11.2 6.1 0.13 11.6 0.3 2.9 3 1 1 4 4 4 0 MalT-like TPR region Chromo PF00385.24 CEG43891.1 - 2.9e-12 46.3 0.0 4.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEG43891.1 - 0.0074 16.4 1.0 0.014 15.5 1.0 1.6 1 1 0 1 1 1 1 Polycomb-like MTF2 factor 2 Actin PF00022.19 CEG43893.1 - 2.3e-101 339.4 0.0 2.8e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEG43893.1 - 0.0046 15.8 0.0 0.037 12.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein WD40 PF00400.32 CEG43895.1 - 1.5e-30 104.7 9.4 3.8e-05 24.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43895.1 - 3.7e-08 33.6 0.0 0.00069 19.9 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG43895.1 - 0.17 11.1 0.0 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain WW PF00397.26 CEG43896.1 - 2.9e-15 56.1 13.2 2.1e-09 37.3 1.7 2.7 2 0 0 2 2 2 2 WW domain IQ PF00612.27 CEG43896.1 - 2.9e-15 54.6 122.9 0.0034 17.0 0.1 17.6 18 1 1 19 19 19 13 IQ calmodulin-binding motif Glyco_hyd_101C PF17451.2 CEG43896.1 - 0.095 13.0 2.9 11 6.3 0.1 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain GCK PF07802.11 CEG43897.1 - 7.4e-16 58.3 3.4 1.6e-15 57.2 3.4 1.6 1 0 0 1 1 1 1 GCK domain bZIP_2 PF07716.15 CEG43899.1 - 0.0023 18.0 2.4 0.0023 18.0 2.4 2.8 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEG43899.1 - 1.1 9.8 11.3 0.51 10.9 4.6 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Cadherin PF00028.17 CEG43902.1 - 0 1363.8 108.6 1e-12 48.3 0.2 74.5 75 0 0 75 75 75 64 Cadherin domain TIG PF01833.24 CEG43902.1 - 2.2e-34 117.4 94.2 6.5e-11 42.2 2.4 17.0 17 0 0 17 17 17 10 IPT/TIG domain Fibrinogen_C PF00147.18 CEG43902.1 - 6.5e-34 117.7 4.1 2.7e-33 115.6 1.0 2.8 3 0 0 3 3 3 1 Fibrinogen beta and gamma chains, C-terminal globular domain Cadherin_4 PF17803.1 CEG43902.1 - 6.8e-33 113.1 255.4 0.00031 21.3 0.8 53.1 55 0 0 55 55 55 19 Bacterial cadherin-like domain Big_9 PF17963.1 CEG43902.1 - 6.4e-25 87.7 268.7 0.0053 17.5 0.1 54.3 60 2 1 61 61 61 18 Bacterial Ig domain Laminin_G_3 PF13385.6 CEG43902.1 - 4.3e-20 72.4 8.3 2.3e-13 50.6 0.1 3.9 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily F5_F8_type_C PF00754.25 CEG43902.1 - 4.9e-12 46.1 0.1 1.3e-08 35.0 0.0 3.0 2 0 0 2 2 2 2 F5/8 type C domain Ephrin_rec_like PF07699.13 CEG43902.1 - 0.00034 20.3 21.7 0.00053 19.7 5.5 6.7 5 1 1 6 6 6 2 Putative ephrin-receptor like GAF_2 PF13185.6 CEG43903.1 - 0.00017 21.9 0.1 0.00053 20.3 0.0 1.9 2 0 0 2 2 2 1 GAF domain FYVE PF01363.21 CEG43903.1 - 0.00022 21.3 13.2 0.00058 19.9 13.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger Sugar_tr PF00083.24 CEG43905.1 - 0.00045 19.2 1.4 0.00081 18.4 1.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Toxin_35 PF10530.9 CEG43905.1 - 1 9.4 5.9 0.098 12.7 0.4 2.2 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Guanylate_cyc PF00211.20 CEG43906.1 - 2.8e-24 85.7 0.1 8.7e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 CEG43906.1 - 1.1e-08 35.5 1.0 1.3e-07 32.1 0.1 2.8 3 0 0 3 3 3 1 PH domain FYVE PF01363.21 CEG43906.1 - 6e-06 26.3 15.4 6e-06 26.3 15.4 2.3 2 0 0 2 2 2 1 FYVE zinc finger AAA_16 PF13191.6 CEG43906.1 - 1.5e-05 25.4 1.5 9.2e-05 22.9 0.4 2.9 2 1 0 2 2 2 1 AAA ATPase domain PH_9 PF15410.6 CEG43906.1 - 0.00036 20.9 0.0 0.0014 19.0 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain TsaE PF02367.17 CEG43906.1 - 0.075 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PH_11 PF15413.6 CEG43906.1 - 0.09 13.2 0.1 0.39 11.1 0.1 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain RNA_pol PF00940.19 CEG43908.1 - 1.8e-155 517.9 0.0 5e-155 516.4 0.0 1.7 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CEG43908.1 - 3.5e-57 194.3 0.0 6.5e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal TPR_17 PF13431.6 CEG43909.1 - 0.00053 20.2 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG43909.1 - 0.037 14.1 0.0 0.14 12.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PspC PF04024.12 CEG43909.1 - 0.052 13.4 0.1 0.052 13.4 0.1 2.9 3 0 0 3 3 3 0 PspC domain TPR_1 PF00515.28 CEG43909.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG43909.1 - 0.078 13.6 0.0 0.22 12.2 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MBOAT_2 PF13813.6 CEG43909.1 - 0.088 13.1 0.9 2.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Membrane bound O-acyl transferase family TPR_9 PF13371.6 CEG43909.1 - 0.1 12.8 0.0 8.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2304 PF10066.9 CEG43909.1 - 0.97 9.7 0.0 0.97 9.7 0.0 4.2 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2304) RRM_1 PF00076.22 CEG43910.1 - 9.3e-18 63.8 0.0 1.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG43910.1 - 9.8e-08 31.6 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M13 PF01431.21 CEG43911.1 - 3.1e-65 219.6 1.3 4.4e-65 219.1 0.4 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CEG43911.1 - 1.1e-59 203.1 0.0 2.2e-43 149.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Snapin_Pallidin PF14712.6 CEG43913.1 - 1.9e-17 63.5 0.0 2.2e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Snapin/Pallidin TRPM_tetra PF16519.5 CEG43913.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Tetramerisation domain of TRPM MscS_porin PF12795.7 CEG43913.1 - 0.035 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ANAPC2 PF08672.11 CEG43913.1 - 0.095 13.2 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 CLZ PF16526.5 CEG43913.1 - 0.096 13.1 0.1 0.49 10.8 0.0 1.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-RING_2 PF13639.6 CEG43914.1 - 3.8e-05 23.9 12.8 0.00019 21.7 12.8 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG43914.1 - 0.00013 21.7 10.1 0.00038 20.2 10.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG43914.1 - 0.00031 20.7 10.4 0.00039 20.4 7.3 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG43914.1 - 0.00033 20.5 14.9 0.00053 19.8 13.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEG43914.1 - 0.00053 20.1 12.6 0.0016 18.6 12.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CEG43914.1 - 0.0013 18.6 9.1 0.0053 16.7 9.1 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEG43914.1 - 0.0023 17.7 14.6 0.0027 17.5 12.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG43914.1 - 0.0049 16.7 10.9 0.016 15.1 10.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CEG43914.1 - 0.044 13.6 0.6 0.044 13.6 0.6 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CEG43914.1 - 0.16 12.3 6.4 0.88 9.9 6.4 2.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CEG43914.1 - 0.61 10.3 7.1 2.8 8.1 7.1 2.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Peptidase_C1 PF00112.23 CEG43915.1 - 5.9e-44 150.8 2.0 5.7e-43 147.5 2.0 2.1 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CEG43915.1 - 0.0018 17.2 3.3 0.54 9.0 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Phage_holin_2_3 PF16080.5 CEG43915.1 - 0.32 10.8 2.3 0.24 11.2 0.3 1.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF5112 PF17139.4 CEG43916.1 - 0.033 13.7 0.1 0.035 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Colipase-like PF15083.6 CEG43917.1 - 0.11 12.7 1.5 0.55 10.4 0.0 2.0 1 1 1 2 2 2 0 Colipase-like RNase_T PF00929.24 CEG43918.1 - 3.9e-15 56.8 0.1 1.5e-14 54.9 0.0 1.8 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CEG43918.1 - 0.00013 21.7 0.0 0.0004 20.1 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease EHD_N PF16880.5 CEG43918.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 N-terminal EH-domain containing protein RVT_2 PF07727.14 CEG43923.1 - 2.1e-08 34.1 0.3 3.3e-08 33.5 0.1 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M99_C PF17129.4 CEG43923.1 - 0.0054 16.9 0.1 0.0088 16.2 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of metallo-carboxypeptidase Cyclin_N PF00134.23 CEG43925.1 - 4.1e-41 139.7 3.8 4.7e-39 133.0 0.1 2.7 2 1 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEG43925.1 - 1e-26 93.4 0.5 4e-26 91.4 0.5 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Evr1_Alr PF04777.13 CEG43925.1 - 0.03 14.8 1.4 0.38 11.2 0.1 2.6 2 1 0 2 2 2 0 Erv1 / Alr family DUF383 PF04063.14 CEG43926.1 - 4.1e-41 140.8 0.1 4e-39 134.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CEG43926.1 - 5.6e-21 74.2 0.9 1.5e-20 72.8 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.9 CEG43926.1 - 0.0011 17.5 0.5 0.44 9.0 0.1 2.8 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Arm PF00514.23 CEG43926.1 - 0.34 11.0 3.1 24 5.2 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cluap1 PF10234.9 CEG43927.1 - 0.14 11.6 3.3 0.23 10.8 3.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4718 PF15842.5 CEG43927.1 - 0.15 11.8 2.1 1.6 8.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) DUF1325 PF07039.11 CEG43929.1 - 3.6e-28 98.3 0.0 5.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 CEG43929.1 - 0.068 13.0 0.1 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain OSK PF17182.4 CEG43930.1 - 0.0064 15.7 0.0 0.0075 15.5 0.0 1.0 1 0 0 1 1 1 1 OSK domain Cu-oxidase_3 PF07732.15 CEG43935.1 - 3.8e-29 101.1 0.4 9.9e-29 99.8 0.2 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CEG43935.1 - 8e-27 94.3 0.0 7.4e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEG43935.1 - 1e-06 28.5 0.3 1.2e-05 25.1 0.4 2.5 2 1 0 2 2 2 1 Multicopper oxidase RNA_Me_trans PF04252.13 CEG43938.1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase OSR1_C PF12202.8 CEG43946.1 - 0.038 14.2 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain MIP PF00230.20 CEG43948.1 - 1.5e-61 208.0 15.2 1.1e-52 179.0 6.1 2.0 2 0 0 2 2 2 2 Major intrinsic protein CPBP PF02517.16 CEG43948.1 - 0.055 13.8 3.1 6.9 7.1 0.9 3.0 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease MIP PF00230.20 CEG43949.1 - 0.00046 20.0 0.1 0.00049 19.9 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 CEG43950.1 - 4.4e-50 170.5 6.5 5.4e-50 170.2 6.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Asp PF00026.23 CEG43951.1 - 1.5e-94 317.0 0.2 1.8e-94 316.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG43951.1 - 1.4e-09 38.4 0.6 3.3e-06 27.4 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG43951.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEG43951.1 - 0.047 14.3 0.0 0.59 10.8 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease ATP_bind_1 PF03029.17 CEG43952.1 - 1.9e-72 243.9 1.0 3.3e-72 243.2 1.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NDK PF00334.19 CEG43952.1 - 4.4e-07 30.0 0.0 1.9e-05 24.7 0.0 2.6 1 1 0 1 1 1 1 Nucleoside diphosphate kinase CbiA PF01656.23 CEG43952.1 - 0.00073 19.6 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CEG43952.1 - 0.0053 15.8 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PK PF00224.21 CEG43953.1 - 5.7e-143 476.0 0.6 1.2e-142 474.9 0.6 1.6 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Glyco_transf_20 PF00982.21 CEG43953.1 - 5.8e-113 378.1 0.0 8.2e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG43953.1 - 3.6e-48 163.7 0.0 6.6e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PK_C PF02887.16 CEG43953.1 - 1.1e-26 93.3 0.7 3e-26 92.0 0.7 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEG43953.1 - 0.00037 19.7 0.1 0.00075 18.7 0.1 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CBM_20 PF00686.19 CEG43953.1 - 0.00055 19.8 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 Starch binding domain Nucleolin_bd PF16725.5 CEG43953.1 - 0.042 13.5 0.0 0.15 11.7 0.0 2.0 1 1 0 1 1 1 0 Nucleolin binding domain PrmA PF06325.13 CEG43955.1 - 3.1e-11 43.2 0.0 6.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEG43955.1 - 1.3e-09 38.6 0.1 3.3e-09 37.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CEG43955.1 - 7.4e-07 28.9 0.0 2.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CEG43955.1 - 2.1e-06 28.3 0.0 4.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 CEG43955.1 - 4.1e-05 23.5 0.2 6.2e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CEG43955.1 - 5.9e-05 23.0 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 CEG43955.1 - 0.00016 21.7 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG43955.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG43955.1 - 0.00034 20.0 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CEG43955.1 - 0.00038 20.3 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEG43955.1 - 0.0049 17.9 0.0 0.01 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEG43955.1 - 0.0084 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 CEG43955.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 CEG43955.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 CEG43955.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TrmK PF04816.12 CEG43955.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Peptidase_S41 PF03572.18 CEG43956.1 - 7.8e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 Tricorn_C1 PF14684.6 CEG43956.1 - 0.087 12.9 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain Abhydrolase_1 PF00561.20 CEG43957.1 - 1.1e-28 100.6 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG43957.1 - 2.3e-05 25.1 0.0 2.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEG43957.1 - 0.0013 18.0 0.0 0.0037 16.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CEG43957.1 - 0.0076 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Ysc84 PF04366.12 CEG43958.1 - 1.4e-38 131.5 0.5 2.5e-38 130.7 0.5 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator UvrD_C PF13361.6 CEG43958.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Dicty_CAR PF05462.11 CEG43959.1 - 3.8e-19 69.0 13.4 2.2e-18 66.4 13.4 2.1 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 CEG43959.1 - 2.1e-14 53.4 12.4 1.1e-13 51.1 12.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 CEG43959.1 - 3.3e-05 23.0 2.7 3.3e-05 23.0 2.7 1.5 2 0 0 2 2 2 1 Ocular albinism type 1 protein Frizzled PF01534.17 CEG43959.1 - 6.5e-05 22.1 1.4 6.5e-05 22.1 1.4 2.0 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 CEG43959.1 - 0.0003 20.2 3.7 0.00041 19.8 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WD40 PF00400.32 CEG43960.1 - 3.4e-50 166.9 8.6 5.3e-11 42.9 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CEG43960.1 - 8e-35 119.9 0.5 1.7e-34 118.9 0.5 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CEG43960.1 - 3.4e-11 43.3 0.0 0.003 17.8 0.0 4.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG43960.1 - 4.9e-07 28.8 5.6 0.0021 16.8 0.0 4.3 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG43960.1 - 0.00079 18.5 0.1 0.64 8.9 0.0 4.1 2 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CEG43960.1 - 0.00094 17.8 0.1 0.61 8.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 CEG43960.1 - 0.023 14.0 0.0 4.2 6.6 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain Lum_binding PF00677.17 CEG43961.1 - 3.9e-44 148.6 0.3 1.7e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain COX15-CtaA PF02628.15 CEG43962.1 - 2.2e-57 194.6 7.1 2.9e-57 194.2 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PX PF00787.24 CEG43963.1 - 4.8e-05 23.3 0.0 6.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 PX domain Viral_DNA_Zn_bi PF03728.13 CEG43964.1 - 0.29 11.7 6.2 0.31 11.6 0.2 2.1 1 1 1 2 2 2 0 Viral DNA-binding protein, zinc binding domain JAMP PF05571.12 CEG43964.1 - 1 8.9 4.7 1.1 8.8 4.7 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Fumble PF03630.14 CEG43965.1 - 1e-115 386.5 0.0 1.2e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Fumble Peptidase_M1 PF01433.20 CEG43967.1 - 3.1e-48 164.2 2.5 5.2e-48 163.5 2.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CEG43967.1 - 1.2e-39 136.4 1.0 9.1e-39 133.6 1.0 2.0 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3251 PF11622.8 CEG43967.1 - 0.14 11.8 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) NDUF_B4 PF07225.12 CEG43968.1 - 0.14 12.1 6.2 0.14 12.0 6.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) zf-RNPHF PF08080.12 CEG43969.1 - 0.07 13.1 0.4 1.5 8.9 0.2 2.3 1 1 1 2 2 2 0 RNPHF zinc finger DUF4205 PF13898.6 CEG43970.1 - 9.3e-100 333.9 0.0 1.3e-99 333.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Myb_DNA-binding PF00249.31 CEG43970.1 - 2.3e-06 27.7 1.9 8.9e-06 25.8 1.9 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG43970.1 - 3.7e-06 27.1 0.4 8.8e-06 25.9 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Phage_CRI PF05144.14 CEG43970.1 - 0.0037 16.6 1.8 0.0037 16.6 1.8 2.2 3 0 0 3 3 3 1 Phage replication protein CRI HsbA PF12296.8 CEG43970.1 - 0.076 13.5 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Myb_DNA-bind_4 PF13837.6 CEG43970.1 - 0.12 12.8 9.5 0.027 14.8 5.6 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lactamase_B_2 PF12706.7 CEG43970.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.32 CEG43971.1 - 1.5e-23 82.6 6.8 7.9e-07 29.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG43971.1 - 5.2e-12 45.9 5.4 0.0033 17.7 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG43971.1 - 0.0016 17.4 0.0 0.2 10.6 0.0 2.9 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CEG43971.1 - 0.15 10.0 2.4 0.18 9.8 0.0 2.1 2 1 0 2 2 2 0 IKI3 family Macoilin PF09726.9 CEG43971.1 - 6.1 5.3 10.0 8.1 4.9 10.0 1.1 1 0 0 1 1 1 0 Macoilin family CS PF04969.16 CEG43972.1 - 0.00091 20.2 0.3 0.0034 18.4 0.3 2.0 1 1 0 1 1 1 1 CS domain ArsA_HSP20 PF17886.1 CEG43972.1 - 0.022 14.3 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 HSP20-like domain found in ArsA Metallophos PF00149.28 CEG43973.1 - 2.7e-14 54.1 0.0 4.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CTP_transf_3 PF02348.19 CEG43974.1 - 1.2e-43 149.6 0.0 1.5e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 CEG43974.1 - 2.1e-05 24.9 0.0 3.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Na_H_Exchanger PF00999.21 CEG43975.1 - 7.8e-65 219.1 37.9 9.6e-65 218.8 37.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NuA4 PF09340.10 CEG43977.1 - 4.5e-14 52.1 0.3 9.3e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF2959 PF11172.8 CEG43980.1 - 0.029 14.5 0.4 0.037 14.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) LRR_6 PF13516.6 CEG43981.1 - 0.29 11.3 1.8 11 6.4 0.0 3.4 3 1 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CEG43981.1 - 0.56 11.0 2.9 45 5.2 0.1 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat Syja_N PF02383.18 CEG43982.1 - 6.4e-75 252.4 0.1 1.5e-74 251.2 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain PH PF00169.29 CEG43982.1 - 0.00067 20.1 0.2 0.004 17.6 0.1 2.3 2 0 0 2 2 2 1 PH domain Pkinase PF00069.25 CEG43983.1 - 6.1e-37 127.4 0.0 2.2e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG43983.1 - 3.2e-33 115.1 0.0 2.5e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DEP PF00610.21 CEG43983.1 - 5.2e-08 32.8 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MENTAL PF10457.9 CEG43983.1 - 0.074 12.9 1.1 0.17 11.7 1.1 1.5 1 0 0 1 1 1 0 Cholesterol-capturing domain APH PF01636.23 CEG43983.1 - 0.083 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 CEG43983.1 - 0.2 11.8 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 ABC1 family EGF_2 PF07974.13 CEG43984.1 - 3.9e-08 33.5 54.9 0.00091 19.5 12.5 5.1 4 1 1 5 5 5 3 EGF-like domain EGF PF00008.27 CEG43984.1 - 0.00013 22.2 4.2 0.00013 22.2 4.2 4.6 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 CEG43984.1 - 0.0097 16.5 6.5 0.0097 16.5 6.5 5.7 6 1 0 6 6 6 2 Human growth factor-like EGF EGF_3 PF12947.7 CEG43984.1 - 0.058 13.6 1.8 0.058 13.6 1.8 4.6 3 1 1 4 4 4 0 EGF domain TRAF6_Z2 PF18048.1 CEG43987.1 - 0.092 12.9 0.3 0.16 12.1 0.3 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Hep_59 PF07052.11 CEG43988.1 - 3.8e-16 59.7 1.5 3.8e-16 59.7 1.5 2.6 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF1027 PF06265.11 CEG43988.1 - 0.051 13.6 0.5 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) DUF4833 PF16117.5 CEG43989.1 - 1e-28 100.1 0.0 1.4e-23 83.5 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4833) MBR1 PF17058.5 CEG43989.1 - 0.012 16.0 4.0 0.015 15.6 4.0 1.3 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 FlxA PF14282.6 CEG43989.1 - 0.31 11.0 7.9 0.55 10.3 7.9 1.4 1 0 0 1 1 1 0 FlxA-like protein Nas2_N PF18265.1 CEG43989.1 - 0.31 11.0 5.8 7.4 6.6 0.8 3.1 3 0 0 3 3 3 0 Nas2 N_terminal domain Lectin_N PF03954.14 CEG43989.1 - 0.38 10.5 2.9 0.75 9.5 0.7 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain UPF0242 PF06785.11 CEG43989.1 - 0.63 10.1 12.0 1.2 9.2 12.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 CEG43989.1 - 1.8 8.9 10.0 6.2 7.1 2.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Bcr-Abl_Oligo PF09036.10 CEG43989.1 - 2.6 8.1 5.0 2.5 8.2 0.4 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4407 PF14362.6 CEG43989.1 - 3.8 6.8 11.6 5.6 6.2 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ead_Ea22 PF13935.6 CEG43989.1 - 3.9 8.1 11.5 3.3 8.4 8.3 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein OmpH PF03938.14 CEG43989.1 - 4.7 7.5 17.5 1e+02 3.2 17.5 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 CEG43989.1 - 4.8 6.2 11.1 6 5.8 11.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TauE PF01925.19 CEG43990.1 - 3.6e-35 121.7 23.9 2.6e-18 66.5 4.6 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE MCM PF00493.23 CEG43992.1 - 9.8e-99 329.0 0.0 1.4e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEG43992.1 - 2e-31 108.5 0.2 3.8e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEG43992.1 - 1e-23 83.5 1.4 2.5e-23 82.3 1.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEG43992.1 - 1.5e-13 51.2 0.1 4.7e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain LRR_8 PF13855.6 CEG43992.1 - 6.2e-10 38.7 8.0 2.2e-06 27.4 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEG43992.1 - 9.3e-09 35.4 12.1 0.00022 21.5 0.4 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Mg_chelatase PF01078.21 CEG43992.1 - 2.5e-08 33.6 0.1 2.2e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG43992.1 - 0.0035 17.2 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEG43992.1 - 0.02 14.6 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain LRR_1 PF00560.33 CEG43992.1 - 0.15 12.7 8.4 9 7.3 0.0 4.8 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CEG43992.1 - 0.25 11.5 7.1 45 4.4 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_hydro_6 PF01341.17 CEG43993.1 - 8.2e-46 157.1 1.2 1e-45 156.8 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Nitroreductase PF00881.24 CEG43994.1 - 2.1e-25 89.7 0.0 2.6e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CEG43994.1 - 0.018 14.6 0.2 4.1 6.9 0.1 2.2 1 1 0 2 2 2 0 Putative TM nitroreductase MatE PF01554.18 CEG43996.1 - 4.5e-63 211.7 26.3 8.6e-33 113.3 7.7 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CEG43996.1 - 0.058 13.5 39.4 0.05 13.7 19.7 4.4 2 2 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Actin PF00022.19 CEG43997.1 - 1.2e-132 442.4 0.0 7.5e-95 317.9 0.0 2.7 1 1 1 2 2 2 2 Actin His_Phos_2 PF00328.22 CEG43999.1 - 4.6e-14 52.6 0.5 1.1e-08 34.9 0.1 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2373 PF10180.9 CEG44000.1 - 1.7e-19 69.4 1.0 3.3e-19 68.5 1.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Roc PF08477.13 CEG44001.1 - 5.4e-06 26.6 0.1 9.1e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG44001.1 - 8.3e-05 22.2 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.6 CEG44001.1 - 0.00016 22.1 0.1 0.0021 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.21 CEG44001.1 - 0.00094 18.7 0.0 0.071 12.6 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 CEG44001.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CEG44001.1 - 0.0083 16.6 0.5 0.045 14.3 0.1 2.6 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 CEG44001.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CEG44001.1 - 0.14 12.3 0.0 0.44 10.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SnoaL PF07366.12 CEG44002.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF4390 PF14334.6 CEG44002.1 - 0.091 12.2 0.9 0.45 9.9 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4390) MAPEG PF01124.18 CEG44003.1 - 5.8e-14 52.1 0.1 7.3e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 MAPEG family PhyH PF05721.13 CEG44004.1 - 1.2e-50 172.7 0.0 1.4e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4785 PF16024.5 CEG44004.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) Cpn60_TCP1 PF00118.24 CEG44005.1 - 7.4e-26 90.8 2.7 2.6e-14 52.8 0.0 2.1 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PLAC8 PF04749.17 CEG44005.1 - 0.34 11.9 2.4 0.63 11.1 0.1 2.5 2 2 0 2 2 2 0 PLAC8 family WW PF00397.26 CEG44008.1 - 5.5e-18 64.8 4.9 5e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 WW domain FF PF01846.19 CEG44008.1 - 5.7e-11 42.4 11.5 3.8e-05 23.8 0.3 5.1 4 2 0 4 4 4 2 FF domain DUF719 PF05334.13 CEG44008.1 - 0.0062 16.8 6.2 0.0062 16.8 6.2 3.9 2 1 1 3 3 3 1 Protein of unknown function (DUF719) MPLKIP PF15502.6 CEG44009.1 - 1.3e-12 47.8 11.4 5.8e-07 29.6 4.0 2.6 1 1 1 2 2 2 2 M-phase-specific PLK1-interacting protein MRP-S23 PF10484.9 CEG44011.1 - 0.00031 21.0 0.3 0.0011 19.2 0.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 CbtA_toxin PF06755.12 CEG44011.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Glyco_trans_2_3 PF13632.6 CEG44012.1 - 0.038 13.9 0.9 0.056 13.4 0.9 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF1129 PF06570.11 CEG44012.1 - 0.11 12.0 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) SLD5_C PF16922.5 CEG44013.1 - 1.1e-12 48.0 0.0 2.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CEG44013.1 - 7.1e-06 26.4 1.4 1.6e-05 25.3 1.4 1.5 1 0 0 1 1 1 1 GINS complex protein NDK PF00334.19 CEG44015.1 - 7.9e-52 174.8 0.0 8.9e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase YccF PF03733.13 CEG44016.1 - 0.032 15.0 5.1 0.088 13.5 5.1 1.7 1 0 0 1 1 1 0 Inner membrane component domain SART-1 PF03343.13 CEG44017.1 - 3.9e-81 273.5 85.4 8.3e-63 212.9 73.1 2.5 1 1 1 2 2 2 2 SART-1 family DUF3854 PF12965.7 CEG44017.1 - 0.13 12.2 1.5 0.68 9.9 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) Ntox28 PF15605.6 CEG44019.1 - 0.064 13.5 0.0 0.074 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin 28 PP-binding PF00550.25 CEG44021.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site Pho88 PF10032.9 CEG44022.1 - 6.8e-37 126.5 0.0 7.5e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4199 PF13858.6 CEG44022.1 - 0.14 12.6 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Aminotran_1_2 PF00155.21 CEG44023.1 - 8.7e-52 176.5 0.0 1e-51 176.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEG44023.1 - 0.0001 21.7 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CEG44023.1 - 0.0034 16.2 0.0 0.0074 15.1 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 CEG44023.1 - 0.014 14.0 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEG44023.1 - 0.036 13.4 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEG44023.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Translin PF01997.16 CEG44025.1 - 2.8e-27 96.1 2.1 2.2e-26 93.1 2.1 2.1 1 1 0 1 1 1 1 Translin family DUF1899 PF08953.11 CEG44027.1 - 1.7e-23 82.2 0.2 3.3e-23 81.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CEG44027.1 - 4e-18 65.0 0.1 7.2e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CEG44027.1 - 1.2e-17 63.9 3.9 0.0006 20.6 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG44027.1 - 2.9e-09 37.1 0.0 0.00011 22.4 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG44027.1 - 0.0017 17.4 0.0 0.73 8.7 0.0 2.8 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Bact_lectin PF18483.1 CEG44028.1 - 3.5e-19 69.6 0.0 3.6e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 CEG44028.1 - 8.1e-15 55.0 0.0 4.1e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain fn3 PF00041.21 CEG44028.1 - 5.5e-09 36.3 0.5 1.7e-08 34.6 0.5 1.9 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 CEG44028.1 - 2.1e-05 24.5 0.2 0.00026 21.0 0.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain Y_phosphatase PF00102.27 CEG44032.1 - 5.1e-64 216.1 0.6 6.3e-64 215.8 0.6 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG44032.1 - 1.4e-05 24.9 0.5 0.00011 22.0 0.5 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CEG44032.1 - 0.02 15.0 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate HypA PF01155.19 CEG44034.1 - 0.014 15.4 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Desulfoferrod_N PF06397.12 CEG44034.1 - 0.032 13.8 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Ribosomal_S27e PF01667.17 CEG44034.1 - 0.062 13.0 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 GRP PF07172.11 CEG44035.1 - 0.0021 18.7 20.8 0.0051 17.5 20.8 1.7 1 0 0 1 1 1 1 Glycine rich protein family Bmt2 PF11968.8 CEG44036.1 - 2.7e-47 161.4 0.0 3.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CEG44036.1 - 0.00036 20.4 0.0 0.0034 17.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEG44036.1 - 0.0028 17.5 0.0 0.0052 16.7 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 CEG44036.1 - 0.071 13.9 0.0 0.49 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Slx4 PF09494.10 CEG44040.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease HLH PF00010.26 CEG44044.1 - 0.57 10.2 4.7 0.35 10.9 2.4 1.9 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Mito_carr PF00153.27 CEG44049.1 - 1.1e-34 118.2 1.7 1e-12 47.8 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CEG44051.1 - 9.1e-49 166.2 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44051.1 - 4.7e-47 160.5 0.0 8e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG44051.1 - 0.046 12.7 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG44051.1 - 0.17 11.2 0.2 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_7 PF02796.15 CEG44052.1 - 0.12 12.5 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF3523 PF12037.8 CEG44053.1 - 1.6e-41 142.5 29.3 2.3e-41 141.9 29.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 CEG44053.1 - 1.1e-22 80.8 0.0 3e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG44053.1 - 3.4e-06 26.9 0.0 1.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CEG44053.1 - 3e-05 23.5 0.0 0.0001 21.8 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEG44053.1 - 4.3e-05 23.8 6.2 0.00083 19.6 0.0 4.1 3 2 0 4 4 4 1 AAA domain AAA_5 PF07728.14 CEG44053.1 - 0.00071 19.6 0.1 0.00071 19.6 0.1 3.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEG44053.1 - 0.0008 19.6 2.6 0.0012 19.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 CEG44053.1 - 0.0012 19.3 0.0 0.0012 19.3 0.0 3.5 2 2 1 3 3 2 1 AAA ATPase domain AAA_3 PF07726.11 CEG44053.1 - 0.0027 17.6 1.4 0.0066 16.3 0.0 2.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CEG44053.1 - 0.0029 17.6 0.1 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CEG44053.1 - 0.0051 16.5 0.1 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEG44053.1 - 0.0057 16.2 3.2 0.41 10.2 0.0 3.3 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CEG44053.1 - 0.0073 16.9 0.0 0.0073 16.9 0.0 3.2 3 2 0 3 3 1 1 AAA domain Zot PF05707.12 CEG44053.1 - 0.011 15.4 0.4 0.6 9.7 0.0 3.3 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) MRF_C1 PF13887.6 CEG44053.1 - 0.012 14.7 0.2 0.25 10.5 0.0 2.9 3 0 0 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 AAA_17 PF13207.6 CEG44053.1 - 0.016 15.6 0.1 0.016 15.6 0.1 3.2 2 1 1 3 3 1 0 AAA domain AAA_14 PF13173.6 CEG44053.1 - 0.017 15.1 0.0 0.075 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG44053.1 - 0.02 14.4 0.0 0.056 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CEG44053.1 - 0.02 15.0 0.2 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CEG44053.1 - 0.042 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CEG44053.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.5 2 1 0 2 2 1 0 AAA domain DUF1524 PF07510.11 CEG44054.1 - 0.2 11.6 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) EF-hand_1 PF00036.32 CEG44056.1 - 1e-22 77.9 16.3 8.5e-06 25.0 0.1 6.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEG44056.1 - 5.7e-22 78.0 5.3 5.2e-10 39.6 1.1 3.9 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG44056.1 - 2.4e-20 70.7 15.5 1.5e-05 24.5 0.8 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CEG44056.1 - 1.1e-15 57.2 10.2 4.1e-07 29.7 0.0 5.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG44056.1 - 1.1e-14 53.2 13.3 0.00031 20.1 0.2 5.1 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 CEG44056.1 - 0.00077 19.8 2.5 3.1 8.2 0.3 4.4 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region PBP_dimer PF03717.15 CEG44056.1 - 0.017 15.4 0.1 0.034 14.5 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF932 PF06067.11 CEG44056.1 - 0.033 14.0 1.8 0.2 11.4 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF932) EF-hand_4 PF12763.7 CEG44056.1 - 0.066 13.2 3.5 6.1 6.9 0.1 3.8 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand ARL2_Bind_BART PF11527.8 CEG44056.1 - 0.13 12.3 10.5 0.51 10.5 0.1 3.7 4 0 0 4 4 4 0 The ARF-like 2 binding protein BART Dockerin_1 PF00404.18 CEG44056.1 - 0.14 12.4 0.0 5.8 7.2 0.0 3.0 4 0 0 4 4 4 0 Dockerin type I domain EF-hand_1 PF00036.32 CEG44058.1 - 2.9e-62 201.7 31.2 3.1e-07 29.5 0.8 13.8 14 0 0 14 14 14 12 EF hand EF-hand_7 PF13499.6 CEG44058.1 - 5.5e-52 174.1 33.8 3.2e-10 40.3 1.6 9.1 7 2 2 9 9 9 9 EF-hand domain pair EF-hand_6 PF13405.6 CEG44058.1 - 1.3e-43 143.2 43.9 1.2e-05 24.9 0.3 13.8 14 0 0 14 14 13 10 EF-hand domain EF-hand_8 PF13833.6 CEG44058.1 - 1.1e-37 127.6 31.5 5.9e-06 26.0 0.7 13.3 9 5 5 14 14 14 8 EF-hand domain pair EF-hand_5 PF13202.6 CEG44058.1 - 2.4e-29 99.5 29.1 1.2e-05 24.6 0.3 11.0 12 0 0 12 12 12 7 EF hand EF-hand_11 PF08976.11 CEG44058.1 - 1e-10 42.4 6.0 0.011 16.6 0.1 6.3 7 0 0 7 7 7 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG44058.1 - 3.5e-08 33.8 2.7 0.87 9.9 0.0 6.5 6 0 0 6 6 6 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG44058.1 - 0.0014 18.6 11.3 2.1 8.3 0.1 7.6 6 3 3 9 9 9 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CEG44058.1 - 0.04 13.8 9.2 8.9 6.3 0.3 5.0 5 0 0 5 5 5 0 EF hand DUF3887 PF13026.6 CEG44058.1 - 0.068 14.0 0.0 37 5.2 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Adenine_glyco PF03352.13 CEG44058.1 - 0.069 12.9 0.2 27 4.5 0.0 3.3 2 0 0 2 2 2 0 Methyladenine glycosylase PDZ PF00595.24 CEG44059.1 - 0.0039 17.5 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M41 PF01434.18 CEG44060.1 - 4.2e-64 215.9 0.1 7e-64 215.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CEG44060.1 - 1.2e-42 145.4 0.0 3.3e-42 144.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG44060.1 - 2.2e-12 46.5 0.2 6.8e-12 45.0 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CEG44060.1 - 2.5e-09 37.4 0.0 6.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CEG44060.1 - 4.3e-06 26.8 0.0 0.0046 17.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG44060.1 - 0.0024 18.1 4.4 0.29 11.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain TIP49 PF06068.13 CEG44060.1 - 0.0031 16.8 1.4 0.0074 15.5 0.1 2.0 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 CEG44060.1 - 0.0045 17.1 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEG44060.1 - 0.011 16.1 0.4 0.2 12.0 0.2 2.6 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 CEG44060.1 - 0.019 14.7 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CEG44060.1 - 0.021 14.2 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEG44060.1 - 0.03 14.1 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CEG44060.1 - 0.062 12.8 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEG44060.1 - 0.086 13.0 0.2 0.24 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CEG44060.1 - 0.092 13.2 0.0 0.64 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEG44060.1 - 0.11 13.0 0.3 3.6 8.1 0.1 2.8 2 0 0 2 2 2 0 ABC transporter SAC3 PF12209.8 CEG44060.1 - 0.29 11.4 1.4 0.62 10.3 1.4 1.5 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Ribosomal_S5 PF00333.20 CEG44061.1 - 8.9e-29 99.3 0.8 2.1e-28 98.1 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CEG44061.1 - 2.2e-08 33.4 0.2 4.1e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CEG44061.1 - 0.5 10.9 12.4 0.88 10.2 12.4 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF2250 PF10007.9 CEG44064.1 - 0.011 15.9 0.3 0.022 14.9 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) RBD-FIP PF09457.10 CEG44065.1 - 0.14 12.1 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 FIP domain RXLR PF16810.5 CEG44065.1 - 0.95 9.9 4.1 2.5 8.5 0.1 3.2 3 1 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity Pkinase PF00069.25 CEG44066.1 - 1.1e-48 165.9 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44066.1 - 1.2e-48 165.7 0.0 1.8e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 CEG44066.1 - 2.6e-09 37.2 19.2 4.3e-07 30.2 3.8 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG44066.1 - 5.1e-08 32.6 18.3 1.8e-06 27.6 2.5 3.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CEG44066.1 - 0.0051 16.8 16.2 4.4 7.6 0.1 4.7 4 0 0 4 4 4 3 Leucine Rich repeat Phage_T7_Capsid PF05396.11 CEG44066.1 - 0.016 15.5 0.0 0.97 9.8 0.0 2.4 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Baculo_E56 PF04639.12 CEG44066.1 - 0.036 13.4 2.8 0.06 12.6 1.9 1.8 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope APH PF01636.23 CEG44066.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sigma_reg_N PF13800.6 CEG44066.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal LRR_1 PF00560.33 CEG44066.1 - 2.5 9.0 11.2 16 6.5 0.1 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat PH PF00169.29 CEG44068.1 - 2.7e-08 34.3 1.4 4.9e-08 33.4 1.4 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG44068.1 - 5.1e-05 23.5 0.7 9.6e-05 22.6 0.7 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 CEG44068.1 - 0.003 17.7 0.1 0.0042 17.2 0.1 1.2 1 0 0 1 1 1 1 PH domain LpqV PF17301.2 CEG44068.1 - 0.0079 16.4 0.4 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Putative lipoprotein LpqV PH_11 PF15413.6 CEG44068.1 - 0.013 15.9 8.9 0.21 12.0 2.1 2.8 1 1 2 3 3 3 0 Pleckstrin homology domain PH_13 PF16652.5 CEG44068.1 - 0.095 12.5 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 CEG44068.1 - 0.12 12.4 2.6 0.64 10.1 2.3 2.0 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DAP3 PF10236.9 CEG44071.1 - 0.00015 21.0 0.1 0.0003 20.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Atg14 PF10186.9 CEG44071.1 - 0.00066 18.9 3.3 0.00085 18.5 3.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_10 PF12846.7 CEG44071.1 - 0.0017 17.4 0.1 0.0017 17.4 0.1 1.8 2 0 0 2 2 2 1 AAA-like domain DUF2124 PF09897.9 CEG44071.1 - 0.0018 18.2 0.1 0.0047 16.8 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) KxDL PF10241.9 CEG44071.1 - 0.0038 17.5 4.0 0.053 13.8 0.8 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein PTS_IIA PF02255.16 CEG44071.1 - 0.0073 16.3 1.1 0.0073 16.3 1.1 2.3 2 0 0 2 2 2 1 PTS system, Lactose/Cellobiose specific IIA subunit RHSP PF07999.11 CEG44071.1 - 0.0074 15.1 0.1 0.016 14.1 0.0 1.5 1 1 0 1 1 1 1 Retrotransposon hot spot protein RsgA_GTPase PF03193.16 CEG44071.1 - 0.01 15.7 1.6 0.045 13.7 0.0 2.5 1 1 2 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 CEG44071.1 - 0.013 15.9 0.2 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain XhlA PF10779.9 CEG44071.1 - 0.016 15.4 8.6 0.18 12.1 1.8 2.7 2 0 0 2 2 2 0 Haemolysin XhlA IstB_IS21 PF01695.17 CEG44071.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein CPDase PF07823.11 CEG44071.1 - 0.019 14.7 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Sec8_exocyst PF04048.14 CEG44071.1 - 0.019 14.9 2.9 0.019 14.9 2.9 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain AAA_5 PF07728.14 CEG44071.1 - 0.026 14.5 0.1 0.061 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LapA_dom PF06305.11 CEG44071.1 - 0.027 14.3 0.2 0.027 14.3 0.2 3.1 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RuvB_N PF05496.12 CEG44071.1 - 0.028 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 CEG44071.1 - 0.04 12.9 0.2 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4398 PF14346.6 CEG44071.1 - 0.043 14.4 1.4 0.043 14.4 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Exonuc_VII_L PF02601.15 CEG44071.1 - 0.048 13.2 2.6 0.068 12.7 2.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_7 PF12775.7 CEG44071.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Occludin_ELL PF07303.13 CEG44071.1 - 0.054 14.2 6.9 0.064 14.0 5.1 2.0 1 1 1 2 2 2 0 Occludin homology domain CbiA PF01656.23 CEG44071.1 - 0.056 13.5 0.6 0.18 11.8 0.0 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LprI PF07007.12 CEG44071.1 - 0.065 13.9 0.6 0.065 13.9 0.6 2.0 3 0 0 3 3 1 0 Lysozyme inhibitor LprI ATPase PF06745.13 CEG44071.1 - 0.069 12.5 3.2 2 7.7 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF2031 PF09592.10 CEG44071.1 - 0.07 12.6 12.6 0.9 9.0 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) AAA_22 PF13401.6 CEG44071.1 - 0.074 13.3 0.4 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG44071.1 - 0.094 12.8 7.2 0.57 10.2 3.8 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain TMPIT PF07851.13 CEG44071.1 - 0.095 11.9 3.3 0.15 11.3 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein AAA_25 PF13481.6 CEG44071.1 - 0.097 12.2 1.9 0.11 12.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain LPD5 PF18799.1 CEG44071.1 - 0.13 12.7 8.3 0.11 12.9 6.6 1.7 2 0 0 2 2 1 0 Large polyvalent protein-associated domain 5 DUF4407 PF14362.6 CEG44071.1 - 0.14 11.5 6.0 0.19 11.0 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0449 PF15136.6 CEG44071.1 - 0.14 12.6 7.0 0.11 13.0 4.3 2.2 2 1 0 2 2 1 0 Uncharacterised protein family UPF0449 DUF501 PF04417.12 CEG44071.1 - 0.2 11.4 1.5 0.32 10.8 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF501) LPP PF04728.13 CEG44071.1 - 0.24 11.8 10.5 0.45 11.0 1.3 3.3 4 1 1 5 5 3 0 Lipoprotein leucine-zipper ERM PF00769.19 CEG44071.1 - 0.25 11.1 12.1 1.9 8.2 12.2 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin PF00261.20 CEG44071.1 - 0.28 10.5 15.6 0.52 9.6 15.6 1.5 1 1 0 1 1 1 0 Tropomyosin KELK PF15796.5 CEG44071.1 - 0.3 11.6 9.2 0.59 10.6 8.2 2.0 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_18 PF13238.6 CEG44071.1 - 0.31 11.6 4.0 2.5 8.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CEG44071.1 - 0.31 10.3 4.3 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ZapB PF06005.12 CEG44071.1 - 0.35 11.3 8.8 0.087 13.3 4.3 2.1 2 0 0 2 2 2 0 Cell division protein ZapB AAA PF00004.29 CEG44071.1 - 0.47 10.9 3.6 0.52 10.7 0.1 2.6 1 1 2 3 3 3 0 ATPase family associated with various cellular activities (AAA) T3SS_needle_E PF08988.10 CEG44071.1 - 0.47 10.6 4.9 0.35 11.1 2.0 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle ATG16 PF08614.11 CEG44071.1 - 0.52 10.5 11.7 0.58 10.3 7.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 CEG44071.1 - 0.64 10.8 6.4 0.67 10.7 4.3 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HicB_lk_antitox PF15919.5 CEG44071.1 - 0.73 10.0 6.1 0.24 11.5 0.3 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system SF3a60_bindingd PF12108.8 CEG44071.1 - 0.98 9.4 6.4 2.5 8.1 0.3 3.1 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain CC2-LZ PF16516.5 CEG44071.1 - 1.6 9.2 13.8 1.2 9.5 3.6 3.3 1 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_13 PF13166.6 CEG44071.1 - 1.8 7.1 12.1 0.78 8.3 9.7 1.5 1 1 1 2 2 2 0 AAA domain OEP PF02321.18 CEG44071.1 - 2.3 8.0 7.7 0.38 10.5 2.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein HrpB7 PF09486.10 CEG44071.1 - 2.4 8.5 14.2 2.5 8.5 4.3 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5082 PF16888.5 CEG44071.1 - 2.8 8.2 11.0 5.1 7.4 2.8 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) COG2 PF06148.11 CEG44071.1 - 2.8 8.0 7.1 4.7 7.3 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 T3SSipB PF16535.5 CEG44071.1 - 3.1 8.2 8.2 1.1 9.8 2.6 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4140 PF13600.6 CEG44071.1 - 7.8 7.0 10.0 2.2e+02 2.4 10.0 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Exo_endo_phos PF03372.23 CEG44072.1 - 0.027 14.0 0.2 0.072 12.6 0.2 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4913 PF16259.5 CEG44072.1 - 0.11 12.6 0.3 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) DHHC PF01529.20 CEG44075.1 - 5.2e-32 110.8 15.1 1.5e-31 109.3 8.6 3.2 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CEG44075.1 - 4.6e-17 62.4 3.6 1.8e-06 28.4 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG44075.1 - 1.5e-16 60.5 5.7 2.3e-06 28.0 0.5 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG44075.1 - 4.1e-14 51.3 1.4 0.059 13.9 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CEG44075.1 - 2.3e-09 37.3 9.2 0.0017 18.6 0.0 5.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG44075.1 - 4.1e-09 36.5 2.3 0.019 15.4 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat SCAMP PF04144.13 CEG44075.1 - 0.021 15.1 1.0 0.021 15.1 1.0 2.7 3 1 0 3 3 3 0 SCAMP family DUF4131 PF13567.6 CEG44075.1 - 0.031 13.9 7.0 0.71 9.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) IGFBP PF00219.18 CEG44075.1 - 2.6 8.8 8.6 5.5 7.7 8.6 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Sybindin PF04099.12 CEG44076.1 - 2.8e-29 101.9 0.0 3.2e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CEG44076.1 - 0.002 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF883 PF05957.13 CEG44078.1 - 8e-08 32.8 5.6 0.043 14.4 0.1 3.5 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CEG44078.1 - 1.2e-07 32.1 16.5 0.032 14.8 0.2 4.8 2 1 0 2 2 2 1 YtxH-like protein Apolipoprotein PF01442.18 CEG44078.1 - 7.9e-07 29.1 0.0 0.024 14.5 0.0 3.0 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 CEG44078.1 - 9.4e-06 25.8 3.7 0.66 10.1 0.1 3.5 1 1 0 3 3 3 3 Apolipophorin-III precursor (apoLp-III) MT0933_antitox PF14013.6 CEG44078.1 - 0.00054 20.2 25.8 0.037 14.3 1.9 5.3 3 3 2 5 5 5 3 MT0933-like antitoxin protein Collagen_mid PF15984.5 CEG44078.1 - 0.0014 18.4 14.1 0.022 14.5 6.8 2.6 1 1 1 2 2 2 2 Bacterial collagen, middle region DUF1451 PF07295.11 CEG44078.1 - 0.003 17.6 0.2 0.47 10.5 0.0 2.6 1 1 1 2 2 2 1 Zinc-ribbon containing domain ApoO PF09769.9 CEG44078.1 - 0.012 15.6 1.2 12 5.9 0.1 3.7 1 1 1 3 3 3 0 Apolipoprotein O EspB PF05802.11 CEG44078.1 - 0.026 14.5 29.9 0.076 13.0 8.6 3.2 1 1 2 3 3 3 0 Enterobacterial EspB protein Perilipin PF03036.16 CEG44078.1 - 0.084 11.9 17.3 0.14 11.2 0.5 3.1 1 1 2 3 3 3 0 Perilipin family ApoC-I PF04691.12 CEG44078.1 - 0.086 12.8 0.0 21 5.1 0.0 3.1 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) TrbL PF04610.14 CEG44078.1 - 0.097 12.4 15.2 0.15 11.8 1.7 3.2 1 1 2 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein RestrictionSfiI PF11487.8 CEG44078.1 - 0.13 12.2 4.7 15 5.4 0.4 3.4 1 1 1 3 3 3 0 Type II restriction enzyme SfiI Phasin_2 PF09361.10 CEG44078.1 - 0.14 12.5 10.2 4.3 7.7 1.6 3.5 1 1 2 3 3 3 0 Phasin protein LXG PF04740.12 CEG44078.1 - 0.19 11.4 2.4 12 5.5 0.1 3.0 1 1 1 3 3 3 0 LXG domain of WXG superfamily PhaP_Bmeg PF09602.10 CEG44078.1 - 0.21 11.5 0.2 13 5.7 0.1 2.3 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Chlorosome_CsmC PF11098.8 CEG44078.1 - 1.4 8.9 35.8 1.1 9.2 14.4 4.1 1 1 3 4 4 4 0 Chlorosome envelope protein C FliE PF02049.18 CEG44078.1 - 2.7 8.2 10.8 2.5 8.3 0.7 3.8 1 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE DUF5473 PF17567.2 CEG44080.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5473) RuvA_N PF01330.21 CEG44082.1 - 0.065 13.3 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 RuvA N terminal domain DUF647 PF04884.14 CEG44083.1 - 1.4e-89 299.9 0.8 2e-89 299.4 0.8 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ank_2 PF12796.7 CEG44083.1 - 7.2e-12 45.7 0.0 6.1e-11 42.8 0.0 2.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG44083.1 - 2.3e-11 44.0 0.1 4.6e-07 30.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG44083.1 - 4.7e-10 38.8 0.9 0.0028 18.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CEG44083.1 - 1e-09 38.4 0.3 0.0011 19.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEG44083.1 - 2.2e-07 31.0 0.0 0.00031 21.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DENN PF02141.21 CEG44084.1 - 1.9e-07 31.2 0.0 5.2e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain RMMBL PF07521.12 CEG44084.1 - 1.7 8.7 4.8 19 5.3 0.1 2.7 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain ptaRNA1_toxin PF12703.7 CEG44085.1 - 0.046 13.8 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system ubiquitin PF00240.23 CEG44086.1 - 4.8e-05 23.0 0.0 9.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PhnJ PF06007.11 CEG44086.1 - 0.25 10.3 1.9 0.39 9.7 1.9 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ AZUL PF16558.5 CEG44087.1 - 3.8e-11 43.1 7.3 3.9e-11 43.0 5.5 2.0 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Gallidermin PF02052.15 CEG44087.1 - 0.55 10.6 4.9 0.81 10.1 3.1 2.3 2 0 0 2 2 2 0 Gallidermin Glycos_transf_3 PF00591.21 CEG44088.1 - 3e-81 272.7 0.1 4.1e-81 272.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CEG44088.1 - 8.7e-12 44.7 0.5 1.7e-11 43.7 0.5 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Annexin PF00191.20 CEG44089.1 - 5.4e-53 176.9 0.1 6e-12 45.5 0.0 4.1 4 0 0 4 4 4 4 Annexin Mannosyl_trans3 PF11051.8 CEG44097.1 - 5.1e-29 101.5 0.0 7e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Metallophos PF00149.28 CEG44099.1 - 4.7e-36 125.2 0.8 6e-36 124.9 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEG44099.1 - 0.00046 20.6 0.1 0.00094 19.6 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CEG44099.1 - 0.043 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Acyltransferase PF01553.21 CEG44100.1 - 4.7e-17 61.9 0.0 6.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Septum_form PF13845.6 CEG44102.1 - 0.041 13.4 1.8 3.1 7.2 0.2 2.1 1 1 1 2 2 2 0 Septum formation Trypsin PF00089.26 CEG44105.1 - 2.2e-25 89.8 0.0 2.8e-24 86.2 0.0 1.9 1 1 0 1 1 1 1 Trypsin Trypsin PF00089.26 CEG44106.1 - 1.5e-05 25.0 0.4 0.0008 19.3 0.4 2.1 1 1 0 1 1 1 1 Trypsin Trypsin PF00089.26 CEG44107.1 - 5.4e-24 85.2 0.0 6.7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG44107.1 - 7.9e-05 23.6 0.0 0.0001 23.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain EF1G PF00647.19 CEG44109.1 - 0.00032 20.7 3.0 0.00032 20.7 3.0 2.9 3 0 0 3 3 3 1 Elongation factor 1 gamma, conserved domain BAP PF06639.11 CEG44109.1 - 0.35 11.2 2.9 6.5 7.2 0.2 2.8 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) DUF413 PF04219.12 CEG44109.1 - 1.2 9.2 5.4 0.62 10.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF FYVE PF01363.21 CEG44110.1 - 0.012 15.8 12.3 0.022 14.9 12.3 1.4 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG44110.1 - 0.64 10.2 6.7 1.3 9.2 6.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG44113.1 - 0.0071 16.5 5.5 0.017 15.2 5.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger SR-25 PF10500.9 CEG44113.1 - 0.16 11.6 7.8 0.25 10.9 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FYVE_2 PF02318.16 CEG44113.1 - 0.65 10.2 7.4 1.2 9.3 6.7 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 CEG44113.1 - 0.79 9.7 5.0 0.32 10.9 1.8 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-AN1 PF01428.16 CEG44113.1 - 1.1 9.4 5.7 5.2 7.3 5.9 2.0 1 1 1 2 2 2 0 AN1-like Zinc finger Pheromone PF08015.11 CEG44113.1 - 1.8 9.7 7.3 82 4.4 0.0 3.1 2 1 1 3 3 3 0 Fungal mating-type pheromone DUF4637 PF15470.6 CEG44113.1 - 4 7.1 8.2 4.5 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) TRP PF06011.12 CEG44118.1 - 4e-20 72.0 16.2 9.2e-20 70.8 16.2 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel MU2_FHA PF18221.1 CEG44118.1 - 0.041 13.9 0.1 0.3 11.2 0.0 2.3 3 0 0 3 3 3 0 Mutator 2 Fork head associated domain FUN14 PF04930.15 CEG44120.1 - 3.5e-19 69.0 2.6 4.6e-19 68.6 1.7 1.6 2 0 0 2 2 2 1 FUN14 family Sugar-bind PF04198.13 CEG44120.1 - 0.12 11.5 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative sugar-binding domain NUDIX PF00293.28 CEG44122.1 - 2.5e-09 37.3 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SoxG PF04268.12 CEG44122.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family RVT_2 PF07727.14 CEG44123.1 - 4.6e-35 121.4 0.1 7.9e-35 120.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEG44123.1 - 3.3e-13 49.9 0.0 9.4e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CEG44123.1 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 CEG44123.1 - 0.0049 16.6 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 CEG44123.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease His_Phos_1 PF00300.22 CEG44124.1 - 4.9e-15 55.7 0.0 1.3e-14 54.4 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 CEG44124.1 - 0.019 15.4 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 PH domain Peptidase_C1 PF00112.23 CEG44125.1 - 1.3e-97 326.1 20.2 1.5e-52 178.8 2.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease SPATA48 PF15073.6 CEG44125.1 - 0.025 14.9 0.0 4.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 Peptidase_C1_2 PF03051.15 CEG44125.1 - 3.6 6.3 11.5 1.4 7.6 1.3 2.8 3 0 0 3 3 3 0 Peptidase C1-like family Kinesin PF00225.23 CEG44126.1 - 1e-106 356.7 4.8 1e-104 350.1 1.2 3.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG44126.1 - 7.6e-26 90.8 0.0 1.9e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding NPV_P10 PF05531.12 CEG44126.1 - 0.28 11.7 12.6 0.088 13.3 0.5 4.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein T3SS_needle_F PF09392.10 CEG44126.1 - 6.1 7.1 5.9 3 8.1 0.1 3.5 4 0 0 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF RNA_pol_Rpb2_6 PF00562.28 CEG44127.1 - 2e-114 382.7 0.4 7.7e-114 380.8 0.4 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEG44127.1 - 4.7e-31 107.9 0.1 8.3e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CEG44127.1 - 1e-28 99.3 0.0 2.5e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CEG44127.1 - 1.6e-22 79.7 0.2 4.8e-22 78.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CEG44127.1 - 7e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 CEG44127.1 - 5.2e-12 45.6 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain NAD_binding_1 PF00175.21 CEG44128.1 - 3.5e-31 108.1 0.0 5.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEG44128.1 - 1.8e-20 73.1 0.0 4.2e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEG44128.1 - 7.2e-06 26.2 0.0 3.6e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain 14-3-3 PF00244.20 CEG44130.1 - 3.8e-104 347.1 3.6 4.3e-104 346.9 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 CEG44130.1 - 0.033 14.5 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Neur PF00064.18 CEG44131.1 - 0.062 12.1 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase FYVE_2 PF02318.16 CEG44133.1 - 0.031 14.5 5.9 0.068 13.4 5.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger KIX PF02172.16 CEG44135.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 KIX domain dCMP_cyt_deam_1 PF00383.23 CEG44136.1 - 1.2e-09 37.9 0.1 2.3e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEG44136.1 - 6.6e-09 35.6 0.1 1.2e-08 34.8 0.1 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CEG44136.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Eisosome1 PF12757.7 CEG44136.1 - 0.37 11.1 4.1 0.79 10.0 4.2 1.6 1 1 0 1 1 1 0 Eisosome protein 1 Pkinase_Tyr PF07714.17 CEG44137.1 - 4.8e-109 363.6 0.0 1.9e-54 184.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEG44137.1 - 4.4e-97 324.6 0.0 1.1e-50 172.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 CEG44137.1 - 0.0001 22.3 0.0 0.3 11.0 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG44137.1 - 0.00018 20.6 0.1 1.9 7.3 0.0 3.8 4 0 0 4 4 4 2 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG44137.1 - 0.0023 16.8 0.0 0.2 10.4 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 CEG44137.1 - 0.065 12.5 0.0 6.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF4131 PF13567.6 CEG44137.1 - 7.8 6.1 5.4 1.1 8.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MMR_HSR1 PF01926.23 CEG44138.1 - 2.4e-14 53.4 0.2 5.8e-13 48.9 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG44138.1 - 2.6e-11 43.7 0.1 1.1e-10 41.7 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CEG44138.1 - 7.7e-08 32.0 0.2 4.7e-06 26.2 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEG44138.1 - 0.0009 18.8 0.1 0.075 12.6 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG44138.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CEG44138.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 CEG44138.1 - 0.024 14.2 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras family Roc PF08477.13 CEG44138.1 - 0.035 14.3 0.1 0.29 11.3 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CEG44138.1 - 0.07 12.5 0.3 1 8.7 0.1 2.2 2 0 0 2 2 2 0 AIG1 family Septin PF00735.18 CEG44138.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin MCM PF00493.23 CEG44138.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 CEG44138.1 - 0.13 12.8 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CEG44138.1 - 0.16 11.4 0.0 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 CEG44138.1 - 0.19 11.7 0.6 7.3 6.6 0.1 2.5 1 1 0 2 2 2 0 Dynamin family BK_channel_a PF03493.18 CEG44139.1 - 4.6e-16 58.8 0.0 1.8e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CEG44139.1 - 3.8e-13 49.2 10.7 7.2e-13 48.3 10.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEG44139.1 - 3.9e-12 45.9 1.9 1.3e-11 44.3 1.9 2.0 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 CEG44139.1 - 4.9e-07 30.0 0.1 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Lig_chan PF00060.26 CEG44139.1 - 0.00019 21.3 0.1 0.00035 20.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_C PF02080.21 CEG44139.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-C domain DEAD PF00270.29 CEG44140.1 - 2e-35 122.1 0.3 3.7e-35 121.3 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG44140.1 - 5.2e-28 97.6 0.1 1.1e-26 93.3 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Glyco_transf_7C PF02709.14 CEG44140.1 - 4.6e-23 80.7 0.0 2e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CEG44140.1 - 7.2e-18 64.5 0.0 1.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 ResIII PF04851.15 CEG44140.1 - 7.1e-06 26.1 0.1 2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEG44140.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG44140.1 - 0.0044 17.3 2.3 0.066 13.5 0.3 3.3 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CEG44140.1 - 0.021 15.1 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Glyco_tranf_2_2 PF10111.9 CEG44140.1 - 0.041 13.3 0.1 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 T2SSE PF00437.20 CEG44140.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein T4SS-DNA_transf PF02534.14 CEG44140.1 - 0.092 11.5 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TBP PF00352.21 CEG44141.1 - 5.2e-34 116.1 0.0 5.1e-28 96.9 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Proteasome PF00227.26 CEG44143.1 - 1.7e-41 141.8 0.0 1.9e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.22 CEG44144.1 - 4.5e-15 55.2 0.0 1.3e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CEG44144.1 - 1.6e-13 50.4 0.3 3.7e-13 49.3 0.3 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 CEG44144.1 - 2.7e-05 24.9 0.0 9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 CEG44144.1 - 0.0024 17.8 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 CEG44144.1 - 0.0037 17.3 0.0 0.03 14.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif AhpC-TSA PF00578.21 CEG44146.1 - 2.1e-22 79.4 0.0 2.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CEG44146.1 - 4.5e-09 36.0 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CEG44146.1 - 1.4e-08 34.6 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Ribosomal_L27A PF00828.19 CEG44147.1 - 1.4e-40 139.0 1.1 2.1e-40 138.4 1.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Jagunal PF07086.12 CEG44148.1 - 0.004 17.3 1.7 0.005 16.9 1.7 1.1 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis DUF4337 PF14235.6 CEG44148.1 - 0.16 12.0 0.3 0.24 11.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Occludin_ELL PF07303.13 CEG44149.1 - 0.001 19.8 0.2 0.0013 19.4 0.2 1.1 1 0 0 1 1 1 1 Occludin homology domain HAUS6_N PF14661.6 CEG44149.1 - 0.0076 15.9 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus FmiP_Thoc5 PF09766.9 CEG44149.1 - 0.0089 15.4 0.2 0.011 15.1 0.2 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Remorin_C PF03763.13 CEG44149.1 - 0.013 15.3 0.9 0.022 14.6 0.9 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region BLOC1_2 PF10046.9 CEG44149.1 - 0.013 15.8 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG17 PF04108.12 CEG44149.1 - 0.017 14.3 0.4 0.02 14.0 0.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF812 PF05667.11 CEG44149.1 - 0.021 13.7 0.1 0.021 13.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran_CTD PF16326.5 CEG44149.1 - 0.042 14.1 2.1 0.084 13.1 2.1 1.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain DASH_Duo1 PF08651.10 CEG44149.1 - 0.043 13.6 0.2 0.092 12.5 0.1 1.6 1 1 0 1 1 1 0 DASH complex subunit Duo1 DUF1664 PF07889.12 CEG44149.1 - 0.05 13.6 0.2 0.068 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.9 CEG44149.1 - 0.058 13.3 2.4 0.65 9.9 0.4 2.4 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin NleF_casp_inhib PF16809.5 CEG44149.1 - 0.17 11.8 0.8 0.21 11.5 0.8 1.1 1 0 0 1 1 1 0 NleF caspase inhibitor Streptin-Immun PF11083.8 CEG44149.1 - 0.22 11.9 1.8 1.3 9.5 1.1 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein RasGAP_C PF03836.15 CEG44150.1 - 0.037 14.2 0.8 0.037 14.2 0.8 2.2 1 1 1 2 2 2 0 RasGAP C-terminus Abi_2 PF07751.11 CEG44150.1 - 0.043 14.1 2.5 0.072 13.3 2.2 1.5 1 1 0 1 1 1 0 Abi-like protein Agenet PF05641.12 CEG44151.1 - 6.1e-06 26.6 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Agenet domain DUF4537 PF15057.6 CEG44151.1 - 0.012 15.6 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Flagellin_N PF00669.20 CEG44152.1 - 0.017 15.2 0.2 0.027 14.6 0.1 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region PhosphMutase PF10143.9 CEG44155.1 - 1.8e-47 161.3 0.0 3.3e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 CEG44155.1 - 8.1e-29 100.7 0.0 1e-28 100.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 CEG44155.1 - 0.00098 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Nucleo_P87 PF07267.11 CEG44156.1 - 1.2 8.0 14.8 1.4 7.6 14.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 V_ATPase_I PF01496.19 CEG44156.1 - 4.9 5.0 6.1 9.6 4.0 6.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Usp PF00582.26 CEG44156.1 - 5.6 7.5 7.1 21 5.6 3.0 2.3 2 0 0 2 2 2 0 Universal stress protein family DUF1336 PF07059.12 CEG44159.1 - 3.9e-70 236.5 0.0 5.1e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 CEG44159.1 - 1.6e-18 66.9 0.3 2.7e-18 66.2 0.3 1.3 1 0 0 1 1 1 1 START domain DEAD PF00270.29 CEG44160.1 - 1.6e-30 106.1 0.0 5.8e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG44160.1 - 7.9e-26 90.6 0.1 1.4e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain fragilysinNterm PF16376.5 CEG44160.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Helicase_C_2 PF13307.6 CEG44160.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain WD40 PF00400.32 CEG44161.1 - 7.9e-31 105.6 28.4 1.3e-06 29.0 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat NLE PF08154.12 CEG44161.1 - 3.5e-19 69.1 0.2 6.5e-19 68.2 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CEG44161.1 - 0.0014 17.3 6.9 0.26 9.9 0.2 4.1 2 1 3 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEG44161.1 - 0.0045 17.2 3.6 0.047 14.0 0.2 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 CEG44161.1 - 0.0047 17.2 0.1 0.36 11.2 0.0 3.4 3 0 0 3 3 3 1 Kelch motif PQQ_3 PF13570.6 CEG44161.1 - 0.026 15.0 1.8 3.7 8.1 0.2 4.0 4 1 0 4 4 4 0 PQQ-like domain rRNA_proc-arch PF13234.6 CEG44162.1 - 1.2e-66 225.4 0.3 3.2e-66 224.0 0.3 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CEG44162.1 - 6.8e-51 172.2 0.7 6.8e-51 172.2 0.7 2.4 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 CEG44162.1 - 3.4e-18 66.0 0.0 2.3e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG44162.1 - 8.4e-07 29.3 0.0 3.6e-05 24.1 0.0 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 CEG44162.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.7 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Tropomyosin PF00261.20 CEG44162.1 - 9.7 5.5 14.3 0.19 11.1 5.6 2.5 3 0 0 3 3 3 0 Tropomyosin Peptidase_M16_C PF05193.21 CEG44163.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain NPP1 PF05630.11 CEG44165.1 - 6.7e-47 160.1 0.2 8.6e-47 159.8 0.2 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 CEG44166.1 - 1.8e-23 83.7 0.0 2e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.11 CEG44167.1 - 8.4e-49 166.4 0.0 1.1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Retrotran_gag_2 PF14223.6 CEG44168.1 - 1e-07 31.7 0.0 2.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type PI-PLC-X PF00388.19 CEG44169.1 - 0.021 14.4 0.0 0.068 12.8 0.0 1.8 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain EspF PF04806.12 CEG44169.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 EspF protein repeat PRP38 PF03371.15 CEG44173.1 - 4.7e-52 176.4 0.0 7e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Enolase_C PF00113.22 CEG44174.1 - 1.9e-147 490.2 0.0 2.5e-147 489.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CEG44174.1 - 2.1e-57 192.9 0.1 3.5e-57 192.2 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CEG44174.1 - 8.5e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CEG44174.1 - 4.3e-08 32.6 0.1 8.7e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus EccE PF11203.8 CEG44174.1 - 0.13 12.6 1.1 13 6.2 0.0 2.9 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Abhydrolase_3 PF07859.13 CEG44175.1 - 1.1e-34 120.1 0.2 2.2e-34 119.2 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEG44175.1 - 2.8e-13 49.5 0.0 4.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEG44175.1 - 0.00062 19.3 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Pro_CA PF00484.19 CEG44176.1 - 0.00073 19.9 0.0 0.0027 18.0 0.0 1.8 1 1 0 1 1 1 1 Carbonic anhydrase rve PF00665.26 CEG44178.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG44178.1 - 0.0064 16.3 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain TcdB_N PF12918.7 CEG44178.1 - 0.087 13.1 0.5 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain PilJ_C PF18223.1 CEG44180.1 - 0.003 18.0 2.6 0.004 17.6 0.4 2.2 2 0 0 2 2 2 1 Pili PilJ C-terminal domain Pox_A32 PF04665.12 CEG44181.1 - 1.6e-08 34.3 0.7 0.00014 21.5 0.1 2.0 2 0 0 2 2 2 2 Poxvirus A32 protein RNA_helicase PF00910.22 CEG44181.1 - 0.065 13.6 0.0 0.25 11.7 0.0 2.0 1 1 1 2 2 2 0 RNA helicase Syd PF07348.12 CEG44181.1 - 0.077 12.7 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 Syd protein (SUKH-2) Sec3_C_2 PF15278.6 CEG44182.1 - 1.2 9.5 5.3 21 5.6 0.1 3.3 3 0 0 3 3 3 0 Sec3 exocyst complex subunit DUF1455 PF07306.11 CEG44182.1 - 4.6 7.2 26.2 0.6 10.1 0.6 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1455) Peptidase_M16_M PF16187.5 CEG44183.1 - 2.2e-84 283.1 0.4 2.2e-84 283.1 0.4 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CEG44183.1 - 2.7e-42 144.2 1.6 4.8e-41 140.2 0.6 3.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEG44183.1 - 4.4e-29 101.8 0.0 1e-20 74.6 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Pkinase PF00069.25 CEG44184.1 - 1e-58 198.8 0.0 1.4e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44184.1 - 1.4e-33 116.3 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 CEG44184.1 - 2.8e-12 46.5 0.0 9.9e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 CEG44184.1 - 3.7e-09 36.3 0.0 6.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEG44184.1 - 0.00077 19.1 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 C2 PF00168.30 CEG44184.1 - 0.0011 19.3 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain APH PF01636.23 CEG44184.1 - 0.0039 17.1 0.2 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG44184.1 - 0.04 12.9 0.1 0.064 12.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CEG44184.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family COPI_assoc PF08507.10 CEG44185.1 - 7.5e-14 51.9 7.0 9.9e-14 51.5 7.0 1.2 1 0 0 1 1 1 1 COPI associated protein Tetraspanin PF00335.20 CEG44185.1 - 0.33 10.6 4.7 1.2 8.8 4.5 1.8 2 0 0 2 2 2 0 Tetraspanin family VPS13_C PF16909.5 CEG44186.1 - 8e-55 185.4 8.3 2.6e-53 180.4 1.4 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CEG44186.1 - 2.1e-29 103.0 2.2 1.3e-28 100.5 1.3 2.8 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CEG44186.1 - 1.5e-27 96.0 0.1 5.6e-27 94.2 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CEG44186.1 - 2.6e-14 53.3 0.1 7.5e-11 41.9 0.0 3.0 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CEG44186.1 - 0.039 14.3 0.3 0.11 12.8 0.3 1.7 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain TolB_like PF15869.5 CEG44187.1 - 0.046 13.0 0.2 0.058 12.6 0.2 1.1 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like IPK PF03770.16 CEG44187.1 - 1.1 9.1 5.7 1.1 9.0 5.7 1.0 1 0 0 1 1 1 0 Inositol polyphosphate kinase FYVE PF01363.21 CEG44189.1 - 7.6e-12 45.2 8.2 1.8e-11 44.0 8.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 CEG44189.1 - 0.00024 20.6 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 CEG44189.1 - 0.0045 17.2 6.7 0.0049 17.1 4.9 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger HypA PF01155.19 CEG44189.1 - 0.061 13.3 3.9 0.057 13.4 1.3 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 CEG44189.1 - 0.16 11.9 5.7 0.052 13.5 2.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L40e PF01020.17 CEG44189.1 - 0.26 11.2 4.0 0.72 9.8 4.0 1.7 1 0 0 1 1 1 0 Ribosomal L40e family zf-B_box PF00643.24 CEG44189.1 - 5.5 7.2 6.3 25 5.1 6.3 2.1 1 1 0 1 1 1 0 B-box zinc finger TGase_elicitor PF16683.5 CEG44190.1 - 1.1e-104 350.1 0.2 1.3e-104 349.9 0.2 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor GPCR_chapero_1 PF11904.8 CEG44194.1 - 8.8e-32 110.8 0.6 1.6e-31 109.9 0.6 1.4 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 CEG44194.1 - 3e-15 56.5 1.1 1.5e-08 35.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) GOLD_2 PF13897.6 CEG44194.1 - 2.4e-10 41.0 0.4 9.2e-06 26.2 0.0 2.5 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking Ank_4 PF13637.6 CEG44194.1 - 2.9e-10 40.5 0.3 1.7e-06 28.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG44194.1 - 6.1e-07 29.6 0.7 0.00062 20.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG44194.1 - 2.6e-06 27.6 0.1 0.12 12.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG44194.1 - 3e-06 27.2 0.1 0.42 11.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 CEG44195.1 - 3.3e-46 157.8 0.0 4.3e-41 141.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44195.1 - 1.3e-17 63.9 0.0 3.3e-16 59.4 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG44195.1 - 1.7e-06 27.6 0.0 6e-06 25.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CEG44195.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEG44195.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PI3_PI4_kinase PF00454.27 CEG44196.1 - 3e-55 187.7 0.0 7.4e-55 186.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEG44196.1 - 4.2e-12 45.7 1.7 6.1e-12 45.1 0.2 2.2 2 0 0 2 2 2 1 FATC domain MIT PF04212.18 CEG44196.1 - 0.058 13.5 0.1 0.28 11.3 0.1 2.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Thioredoxin PF00085.20 CEG44200.1 - 2.4e-59 197.7 0.0 8.3e-29 99.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CEG44200.1 - 6.3e-11 42.7 0.1 0.00016 22.1 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG44200.1 - 1.1e-08 35.3 0.0 0.003 17.9 0.0 4.1 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.6 CEG44200.1 - 1.8e-08 34.5 0.0 0.015 15.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CEG44200.1 - 2.6e-07 30.6 0.1 0.0013 18.6 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.6 CEG44200.1 - 2.7e-06 27.3 0.0 0.062 13.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.6 CEG44200.1 - 1.1e-05 25.6 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CEG44200.1 - 1.8e-05 24.3 0.0 0.24 10.7 0.0 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CEG44200.1 - 2.4e-05 24.1 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 CEG44200.1 - 0.00057 19.8 0.0 1.2 8.9 0.0 2.8 3 1 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 CEG44200.1 - 0.0059 16.8 0.9 6.2 7.0 0.1 3.3 2 2 1 3 3 3 1 Thioredoxin Glutaredoxin PF00462.24 CEG44200.1 - 0.0071 16.5 1.7 0.46 10.8 0.1 3.2 2 2 0 2 2 2 1 Glutaredoxin DDE_Tnp_1_2 PF13586.6 CEG44200.1 - 0.059 13.8 0.0 5 7.6 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Red1 PF07964.11 CEG44203.1 - 0.033 12.5 0.1 0.033 12.5 0.1 1.0 1 0 0 1 1 1 0 Rec10 / Red1 zf-RING_11 PF17123.5 CEG44206.1 - 0.081 12.7 0.0 1.6 8.5 0.0 2.3 1 1 0 1 1 1 0 RING-like zinc finger Asp_Arg_Hydrox PF05118.15 CEG44207.1 - 2e-37 128.5 0.3 7.2e-37 126.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_11 PF08241.12 CEG44207.1 - 1.3e-17 64.3 0.2 3.9e-17 62.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG44207.1 - 3.6e-16 59.3 0.1 7.5e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG44207.1 - 1.3e-14 54.7 0.0 4.4e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG44207.1 - 7e-14 52.0 0.1 1.2e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG44207.1 - 4.3e-13 49.9 0.2 1.2e-12 48.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG44207.1 - 2e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CEG44207.1 - 5.7e-06 26.3 0.2 0.00043 20.2 0.0 2.5 1 1 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 CEG44207.1 - 2.4e-05 23.9 0.0 7.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CEG44207.1 - 0.0004 19.8 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 CEG44207.1 - 0.00042 19.8 0.0 0.0067 15.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 CEG44207.1 - 0.0015 18.1 0.2 0.0032 17.1 0.2 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CEG44207.1 - 0.003 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF4456 PF14644.6 CEG44207.1 - 0.0036 17.0 2.4 0.0089 15.7 2.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) PrmA PF06325.13 CEG44207.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 CEG44207.1 - 0.0064 15.8 0.0 0.017 14.5 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 CEG44207.1 - 0.0068 15.9 0.0 0.48 9.9 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.16 CEG44207.1 - 0.021 13.9 0.0 0.055 12.6 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme Methyltransf_5 PF01795.19 CEG44207.1 - 0.073 12.6 0.0 0.75 9.2 0.0 2.0 1 1 1 2 2 2 0 MraW methylase family Poxvirus_B22R_N PF13169.6 CEG44207.1 - 0.1 13.1 0.0 5.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal rRNA_methylase PF06962.12 CEG44207.1 - 0.14 12.1 0.1 1.9 8.5 0.1 2.7 1 1 0 1 1 1 0 Putative rRNA methylase TRAPP PF04051.16 CEG44208.1 - 1.6e-39 135.0 0.0 1.8e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Peroxin-22 PF12827.7 CEG44209.1 - 0.00065 19.6 0.2 0.0034 17.3 0.2 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3480 PF11979.8 CEG44209.1 - 0.036 13.0 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Cpn60_TCP1 PF00118.24 CEG44210.1 - 1.1e-19 70.5 0.0 3.9e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-TAZ PF02135.16 CEG44210.1 - 0.22 12.0 3.6 0.27 11.7 1.2 2.4 2 0 0 2 2 2 0 TAZ zinc finger TPR_12 PF13424.6 CEG44212.1 - 7.6e-17 61.4 1.7 3e-10 40.2 0.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat WW PF00397.26 CEG44212.1 - 3.3e-06 27.1 0.8 3.3e-06 27.1 0.8 2.2 3 0 0 3 3 3 1 WW domain TPR_10 PF13374.6 CEG44212.1 - 6.5e-06 25.8 3.5 0.079 12.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44212.1 - 1.6e-05 24.5 0.8 1.9 8.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44212.1 - 0.00012 21.9 0.3 0.66 10.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat PH PF00169.29 CEG44212.1 - 0.0064 17.0 0.4 0.076 13.5 0.0 3.0 3 0 0 3 3 3 1 PH domain T4bSS_IcmS PF12608.8 CEG44212.1 - 0.051 13.9 1.4 6.3 7.2 0.0 4.4 3 0 0 3 3 3 0 Type IVb secretion, IcmS, effector-recruitment TPR_14 PF13428.6 CEG44212.1 - 0.056 14.3 0.4 1.8 9.6 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44212.1 - 0.069 13.4 1.4 31 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44212.1 - 0.11 12.6 1.4 26 5.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 CEG44213.1 - 3.8e-12 46.2 0.3 6.4e-11 42.3 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 CEG44213.1 - 1.4e-09 38.1 0.0 1.2e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CEG44213.1 - 0.00088 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DZR PF12773.7 CEG44213.1 - 0.41 10.7 4.9 0.28 11.3 2.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-UBR PF02207.20 CEG44213.1 - 1.1 9.5 4.3 3.2 8.0 4.3 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Prenyltransf PF01255.19 CEG44214.1 - 1.9e-70 236.9 0.0 2.5e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cid2 PF09774.9 CEG44214.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 IQ PF00612.27 CEG44215.1 - 3.3e-09 35.7 37.8 0.0027 17.4 0.4 7.3 6 0 0 6 6 6 6 IQ calmodulin-binding motif FAM184 PF15665.5 CEG44218.1 - 0.0049 16.7 26.4 0.041 13.7 4.1 3.0 2 1 1 3 3 3 3 Family with sequence similarity 184, A and B Tup_N PF08581.10 CEG44218.1 - 0.042 14.1 3.3 0.042 14.1 3.3 4.6 2 2 1 4 4 4 0 Tup N-terminal TLE_N PF03920.15 CEG44218.1 - 1 9.4 9.3 0.62 10.1 0.1 3.4 2 2 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Minor_capsid_2 PF11114.8 CEG44225.1 - 0.11 12.5 0.1 8 6.5 0.0 2.3 2 0 0 2 2 2 0 Minor capsid protein AAA_lid_2 PF17863.1 CEG44227.1 - 0.023 14.5 0.1 0.023 14.5 0.1 1.0 1 0 0 1 1 1 0 AAA lid domain COX3 PF00510.18 CEG44229.1 - 8.3e-07 29.1 1.1 9.3e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase subunit III HTH_Tnp_IS630 PF01710.16 CEG44231.1 - 0.16 12.0 0.6 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Transposase Histone_HNS PF00816.21 CEG44235.1 - 8.8e-06 26.5 1.6 0.0044 17.8 0.3 2.5 1 1 2 3 3 3 2 H-NS histone family DUF4797 PF16051.5 CEG44236.1 - 0.0017 18.3 0.3 0.0045 16.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4797) Mito_carr PF00153.27 CEG44240.1 - 1.3e-49 166.0 0.3 2.5e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Di19 PF05605.12 CEG44241.1 - 0.00046 20.4 9.7 0.29 11.5 4.1 3.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CEG44241.1 - 0.032 15.1 5.8 29 5.9 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger HEAT PF02985.22 CEG44241.1 - 0.039 14.2 0.6 0.67 10.4 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Lar_restr_allev PF14354.6 CEG44241.1 - 0.049 14.0 9.6 0.097 13.1 0.7 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar HEAT_EZ PF13513.6 CEG44241.1 - 0.1 13.1 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 HEAT-like repeat PRP21_like_P PF12230.8 CEG44241.1 - 0.13 12.1 2.4 5.2 6.9 0.7 3.0 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf_C2H2_13 PF18508.1 CEG44241.1 - 0.17 11.5 2.8 0.44 10.2 0.2 2.5 1 1 1 2 2 2 0 Zinc finger domain zf_UBZ PF18439.1 CEG44241.1 - 0.26 10.9 10.3 0.4 10.3 0.1 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Ogr_Delta PF04606.12 CEG44241.1 - 0.45 10.5 5.8 10 6.2 0.0 4.0 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zinc_ribbon_15 PF17032.5 CEG44241.1 - 1.4 9.7 10.1 1 10.1 4.9 2.8 2 1 1 3 3 3 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 CEG44241.1 - 1.7 8.2 13.2 0.21 11.1 0.5 3.7 4 0 0 4 4 4 0 TFIIB zinc-binding zf-CHY PF05495.12 CEG44241.1 - 2.4 8.7 9.8 22 5.7 7.1 3.0 2 1 1 3 3 3 0 CHY zinc finger Uma2 PF05685.12 CEG44242.1 - 6.3e-12 45.4 0.0 9.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Inhibitor_I48 PF10467.9 CEG44243.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Peptidase_C27 PF05407.12 CEG44245.1 - 0.087 12.9 0.1 0.088 12.9 0.1 1.0 1 0 0 1 1 1 0 Rubella virus endopeptidase COX7a PF02238.15 CEG44247.1 - 0.073 13.5 1.1 0.11 12.9 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Peptidase_M9_N PF08453.10 CEG44250.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M9 N-terminal DRIM PF07539.12 CEG44250.1 - 0.022 13.1 0.1 0.025 12.9 0.1 1.0 1 0 0 1 1 1 0 Down-regulated in metastasis TGase_elicitor PF16683.5 CEG44252.1 - 6.6e-48 163.3 0.2 8.1e-48 163.0 0.2 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Colipase-like PF15083.6 CEG44252.1 - 0.024 14.7 0.2 0.046 13.9 0.2 1.4 1 0 0 1 1 1 0 Colipase-like Milton PF12448.8 CEG44252.1 - 0.05 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinesin associated protein Glyco_hydro_63 PF03200.16 CEG44252.1 - 0.087 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain B9-C2 PF07162.11 CEG44256.1 - 2.6e-17 63.5 0.0 4.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4875 PF16175.5 CEG44256.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) RINGv PF12906.7 CEG44257.1 - 3e-13 49.7 6.7 3e-13 49.7 6.7 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CEG44257.1 - 0.0007 19.9 6.1 0.002 18.4 6.1 1.9 1 0 0 1 1 1 1 Ring finger domain Kazal_2 PF07648.15 CEG44259.1 - 4.4e-08 33.1 1.3 7.8e-08 32.3 1.3 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG44259.1 - 3e-07 30.3 2.4 5.1e-07 29.6 2.4 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF4995 PF16386.5 CEG44260.1 - 0.057 13.4 4.8 0.2 11.7 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function CENP-F_leu_zip PF10473.9 CEG44260.1 - 0.18 11.8 28.4 2.1 8.3 23.0 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CEG44260.1 - 0.22 10.8 14.3 0.83 8.9 9.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MutH PF02976.15 CEG44260.1 - 0.29 11.2 5.6 0.58 10.2 0.5 2.4 1 1 0 2 2 2 0 DNA mismatch repair enzyme MutH FOXP-CC PF16159.5 CEG44260.1 - 0.3 11.7 11.9 2.1 9.0 1.0 3.5 3 1 0 3 3 3 0 FOXP coiled-coil domain ZnuA PF01297.17 CEG44260.1 - 0.47 9.8 7.7 0.15 11.5 5.0 1.5 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic TMF_DNA_bd PF12329.8 CEG44260.1 - 0.63 10.1 27.4 0.092 12.8 8.6 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 CEG44260.1 - 1.7 8.5 15.5 2.1 8.1 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 CEG44260.1 - 2.2 7.6 25.3 6.9 6.0 25.3 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 CEG44260.1 - 6.5 7.1 26.7 0.72 10.2 10.4 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DDE_1 PF03184.19 CEG44261.1 - 1.7e-09 37.6 0.0 1.8e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Albumin_I_a PF16720.5 CEG44262.1 - 4.4 7.3 14.1 4.4 7.3 0.6 3.9 2 1 2 4 4 4 0 Albumin I chain a WD40 PF00400.32 CEG44264.1 - 9e-13 48.5 0.4 0.066 14.1 0.0 5.8 4 1 1 5 5 5 3 WD domain, G-beta repeat SUKH_6 PF14568.6 CEG44264.1 - 0.031 14.7 0.2 1.4 9.4 0.0 2.9 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall F-actin_cap_A PF01267.17 CEG44265.1 - 1.3e-76 257.5 0.0 1.5e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Ras PF00071.22 CEG44266.1 - 9e-15 54.6 0.0 1.8e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CEG44266.1 - 2.5e-12 47.1 0.0 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG44266.1 - 3.8e-08 33.0 0.0 5.9e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 CEG44266.1 - 6.3e-05 23.5 0.0 0.00017 22.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CEG44266.1 - 8.5e-05 22.6 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEG44266.1 - 9e-05 22.9 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CEG44266.1 - 0.00048 20.1 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CEG44266.1 - 0.00078 18.8 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Septin MCM PF00493.23 CEG44266.1 - 0.0025 17.0 0.0 0.009 15.1 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain G-alpha PF00503.20 CEG44266.1 - 0.0027 16.9 0.0 0.14 11.3 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 CEG44266.1 - 0.0065 16.8 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEG44266.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEG44266.1 - 0.013 15.9 0.0 0.035 14.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.6 CEG44266.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CEG44266.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEG44266.1 - 0.018 14.9 0.0 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 CEG44266.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEG44266.1 - 0.023 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 CEG44266.1 - 0.038 14.0 0.0 0.078 13.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 CEG44266.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 CEG44266.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 CEG44266.1 - 0.057 13.9 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CEG44266.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 CEG44266.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CEG44266.1 - 0.081 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEG44266.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CEG44266.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 CEG44266.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEG44266.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CEG44266.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 CEG44266.1 - 0.16 11.5 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 CEG44266.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 CEG44266.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain WBP-1 PF11669.8 CEG44267.1 - 4e-05 24.2 0.4 9.9e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4381 PF14316.6 CEG44267.1 - 0.0064 16.7 0.8 0.0064 16.7 0.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Mucin PF01456.17 CEG44267.1 - 0.023 14.7 1.8 0.034 14.1 0.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Rhabdo_glycop PF00974.18 CEG44267.1 - 0.035 12.6 1.2 0.054 12.0 1.2 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein EphA2_TM PF14575.6 CEG44267.1 - 0.043 14.7 0.0 0.15 13.0 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 CEG44267.1 - 0.072 13.4 1.4 0.22 11.8 1.4 1.8 1 0 0 1 1 1 0 LST-1 protein TMIE PF16038.5 CEG44267.1 - 0.11 12.4 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 TMIE protein TMEM154 PF15102.6 CEG44267.1 - 0.11 12.3 2.6 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family Comm PF15957.5 CEG44267.1 - 0.23 11.8 0.2 0.23 11.8 0.2 2.1 3 0 0 3 3 3 0 Commissureless Shisa PF13908.6 CEG44267.1 - 0.6 10.3 23.3 0.019 15.2 6.1 3.4 2 2 1 4 4 4 0 Wnt and FGF inhibitory regulator RCR PF12273.8 CEG44267.1 - 0.95 10.1 10.8 3 8.5 10.7 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MAP70 PF07058.11 CEG44267.1 - 2.6 6.7 6.7 4 6.1 6.7 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 LYRIC PF15686.5 CEG44267.1 - 5.9 6.3 6.9 0.36 10.3 0.7 1.9 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family Fn3-like PF14310.6 CEG44268.1 - 2.5e-13 49.9 0.0 3.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain OATP PF03137.20 CEG44274.1 - 0.017 13.4 0.0 0.025 12.9 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMEM154 PF15102.6 CEG44274.1 - 0.11 12.4 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family DUF4632 PF15451.6 CEG44275.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase_Tyr PF07714.17 CEG44276.1 - 3.8e-10 39.5 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG44276.1 - 7.8e-09 35.3 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PARM PF17061.5 CEG44276.1 - 1.6e-05 25.2 13.7 1.6e-05 25.2 13.7 1.4 1 1 0 1 1 1 1 PARM Amnionless PF14828.6 CEG44276.1 - 0.00043 19.2 0.0 0.00056 18.9 0.0 1.1 1 0 0 1 1 1 1 Amnionless S1FA PF04689.13 CEG44276.1 - 0.0024 18.0 0.2 0.004 17.3 0.2 1.3 1 0 0 1 1 1 1 DNA binding protein S1FA FixQ PF05545.11 CEG44276.1 - 0.012 15.6 0.2 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.6 CEG44276.1 - 8.2 6.3 11.8 1.6e+03 -1.1 11.8 2.9 1 1 0 1 1 1 0 TMEM154 protein family Pkinase PF00069.25 CEG44277.1 - 4.5e-13 49.2 0.0 5.4e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44277.1 - 2.4e-12 46.7 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATP_bind_1 PF03029.17 CEG44278.1 - 7.4e-79 264.9 0.1 1.2e-78 264.3 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CEG44278.1 - 7.7e-10 38.6 0.0 2.5e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CEG44278.1 - 7.3e-07 28.8 0.1 0.00011 21.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CEG44278.1 - 4.5e-06 26.7 0.0 2.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CEG44278.1 - 6.5e-06 25.8 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CEG44278.1 - 4.2e-05 22.7 0.1 0.0048 15.9 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CEG44278.1 - 0.00044 19.9 0.3 0.0023 17.6 0.0 2.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 CEG44278.1 - 0.00045 20.8 0.0 0.0013 19.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 CEG44278.1 - 0.00049 20.1 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 NTPase Arf PF00025.21 CEG44278.1 - 0.00084 18.8 0.0 0.14 11.6 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family NACHT PF05729.12 CEG44278.1 - 0.0014 18.6 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CEG44278.1 - 0.0018 18.7 0.1 0.0038 17.6 0.0 1.8 1 1 1 2 2 1 1 AAA ATPase domain AAA_24 PF13479.6 CEG44278.1 - 0.0037 17.0 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CEG44278.1 - 0.0044 16.8 1.4 0.034 13.9 0.1 2.5 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CEG44278.1 - 0.0044 16.2 0.1 0.54 9.4 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 CEG44278.1 - 0.0049 16.8 0.0 4.5 7.1 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 CEG44278.1 - 0.0057 16.8 0.7 0.0079 16.4 0.1 1.8 2 1 0 2 2 1 1 AAA domain Roc PF08477.13 CEG44278.1 - 0.0061 16.8 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEG44278.1 - 0.0085 15.5 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 CEG44278.1 - 0.01 15.7 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 CEG44278.1 - 0.012 15.9 0.2 0.043 14.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 CEG44278.1 - 0.012 15.0 0.0 0.47 9.9 0.0 2.4 3 0 0 3 3 2 0 PhoH-like protein CbiA PF01656.23 CEG44278.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 CEG44278.1 - 0.015 14.5 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 CEG44278.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CEG44278.1 - 0.017 14.7 0.1 2.7 7.5 0.0 2.7 2 1 0 2 2 2 0 Ras family MobB PF03205.14 CEG44278.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 CEG44278.1 - 0.028 14.2 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CEG44278.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CEG44278.1 - 0.032 13.5 0.0 0.72 9.1 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_31 PF13614.6 CEG44278.1 - 0.047 13.6 0.1 0.91 9.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 CEG44278.1 - 0.053 13.6 0.3 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 CEG44278.1 - 0.081 12.3 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 CEG44278.1 - 0.083 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Dynamin_N PF00350.23 CEG44278.1 - 0.086 12.9 0.1 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DLIC PF05783.11 CEG44278.1 - 0.096 11.5 0.1 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) APS_kinase PF01583.20 CEG44278.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase UvrD-helicase PF00580.21 CEG44278.1 - 0.13 11.8 0.2 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 CEG44278.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAIM1 PF06905.13 CEG44279.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Myb_DNA-binding PF00249.31 CEG44280.1 - 9.6e-08 32.1 0.1 3.6e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain DUF4200 PF13863.6 CEG44280.1 - 0.037 14.4 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Myb_DNA-binding PF00249.31 CEG44281.1 - 1.8e-10 40.8 0.1 2.7e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain VPS9 PF02204.18 CEG44282.1 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SMC_Nse1 PF07574.13 CEG44283.1 - 0.0032 17.4 0.1 0.0037 17.2 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Beta-lactamase2 PF13354.6 CEG44283.1 - 0.024 14.3 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family BTB PF00651.31 CEG44283.1 - 0.05 13.8 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Myosin_head PF00063.21 CEG44284.1 - 4.2e-217 722.6 1.7 4.9e-217 722.3 0.2 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CEG44284.1 - 1.2e-27 93.1 59.6 1e-05 24.9 0.3 10.3 10 0 0 10 10 10 9 IQ calmodulin-binding motif AAA_22 PF13401.6 CEG44284.1 - 0.019 15.3 1.4 0.17 12.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CEG44284.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CEG44284.1 - 0.38 11.1 0.0 0.38 11.1 0.0 4.4 3 2 1 4 4 4 0 AAA ATPase domain NtA PF03146.15 CEG44284.1 - 0.61 10.0 11.2 1.5 8.7 1.3 3.8 4 0 0 4 4 4 0 Agrin NtA domain HisK_sensor PF18698.1 CEG44284.1 - 0.61 10.5 3.4 2.5 8.5 3.4 2.0 1 0 0 1 1 1 0 Histidine kinase sensor domain Pkinase PF00069.25 CEG44285.1 - 3.5e-60 203.6 0.0 7.6e-60 202.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44285.1 - 2.4e-23 82.8 0.0 3e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG44285.1 - 2.9e-05 23.6 0.0 0.004 16.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEG44285.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG44285.1 - 0.012 15.5 0.1 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG44285.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L2_C PF03947.18 CEG44286.1 - 5.4e-47 159.1 1.8 8e-47 158.6 1.8 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEG44286.1 - 6.8e-17 61.2 0.0 1.8e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cir_N PF10197.9 CEG44287.1 - 0.0045 17.1 11.9 0.0045 17.1 11.9 3.7 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Dak1 PF02733.17 CEG44288.1 - 1.9e-110 368.6 1.9 2.9e-110 368.0 1.9 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CEG44288.1 - 8.9e-42 142.9 3.0 1.7e-41 142.0 3.0 1.5 1 0 0 1 1 1 1 DAK2 domain S4 PF01479.25 CEG44290.1 - 9.7e-13 47.6 0.0 2.4e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CEG44290.1 - 5.6e-09 36.8 0.6 9.4e-09 36.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain GlutR_dimer PF00745.20 CEG44290.1 - 0.074 13.5 0.0 0.55 10.7 0.0 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2019 PF09450.10 CEG44290.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DKCLD PF08068.12 CEG44291.1 - 1.2e-32 111.8 1.6 2.1e-30 104.6 0.6 3.3 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 CEG44291.1 - 9.8e-22 77.9 9.5 4.6e-21 75.7 0.8 4.0 3 1 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CEG44291.1 - 3.8e-21 75.0 0.5 8.2e-21 73.9 0.5 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CEG44291.1 - 3.4e-19 68.6 2.3 8.2e-19 67.3 2.3 1.7 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.12 CEG44291.1 - 0.13 12.6 11.5 0.23 11.7 11.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family FIST_C PF10442.9 CEG44291.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 FIST C domain RR_TM4-6 PF06459.12 CEG44291.1 - 0.53 10.1 17.8 0.87 9.4 17.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 CEG44291.1 - 0.9 9.3 16.1 0.012 15.4 8.5 1.8 2 0 0 2 2 2 0 Coilin N-terminus NYD-SP28_assoc PF14775.6 CEG44292.1 - 2.1 8.5 7.2 0.32 11.1 0.4 2.9 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF2048 PF09752.9 CEG44293.1 - 9.6e-68 228.8 0.0 1.1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 CEG44293.1 - 4e-08 34.1 1.3 1.3e-07 32.4 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEG44293.1 - 1.4e-07 31.4 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG44293.1 - 0.00018 20.8 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CEG44293.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S28 PF05577.12 CEG44293.1 - 0.21 10.4 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HSP70 PF00012.20 CEG44298.1 - 1.2e-40 139.3 3.8 1.3e-40 139.2 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein ATP-gua_Ptrans PF00217.19 CEG44300.1 - 5.6e-71 238.4 0.0 6.7e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain Gag_p24 PF00607.20 CEG44301.1 - 0.043 13.7 0.4 0.077 12.8 0.2 1.6 1 1 1 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) DUF3824 PF12868.7 CEG44302.1 - 0.36 11.5 3.4 0.83 10.3 3.4 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Tup_N PF08581.10 CEG44302.1 - 0.6 10.4 10.1 0.18 12.1 6.5 1.9 2 0 0 2 2 2 0 Tup N-terminal DUF4407 PF14362.6 CEG44302.1 - 1.1 8.5 4.3 1.5 8.1 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 CEG44302.1 - 1.1 7.7 3.4 1.9 7.0 3.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Kinesin_assoc PF16183.5 CEG44302.1 - 3.3 7.8 5.1 7.3 6.7 5.1 1.7 1 1 0 1 1 1 0 Kinesin-associated DUF3752 PF12572.8 CEG44304.1 - 2.1e-12 47.8 0.8 2.1e-12 47.8 0.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) EI24 PF07264.11 CEG44305.1 - 2.1e-32 112.8 13.1 3.6e-32 112.0 13.1 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TPR_1 PF00515.28 CEG44305.1 - 1.3e-05 24.8 1.6 0.041 13.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44305.1 - 2.1e-05 24.3 4.6 0.016 15.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44305.1 - 0.014 15.7 1.2 0.25 11.7 1.2 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG44305.1 - 0.022 14.9 0.8 0.052 13.7 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44305.1 - 0.053 14.0 1.6 0.15 12.6 1.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat OFCC1 PF15680.5 CEG44305.1 - 0.16 12.5 0.9 0.32 11.6 0.9 1.5 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein TPR_8 PF13181.6 CEG44305.1 - 1.9 8.9 5.3 5.6 7.4 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 CEG44306.1 - 1.3e-15 57.5 12.7 0.00018 22.0 0.1 10.6 9 2 3 12 12 12 2 HEAT-like repeat HEAT_2 PF13646.6 CEG44306.1 - 1.5e-14 54.1 10.9 0.0048 17.3 0.0 8.1 7 1 3 10 10 10 4 HEAT repeats HEAT PF02985.22 CEG44306.1 - 2.4e-14 52.2 23.6 1.2e-05 25.1 0.0 13.4 15 0 0 15 15 15 1 HEAT repeat IBN_N PF03810.19 CEG44306.1 - 6.2e-11 42.1 1.3 1.4e-06 28.1 0.3 3.0 2 0 0 2 2 2 2 Importin-beta N-terminal domain Cnd1 PF12717.7 CEG44306.1 - 2.6e-08 34.1 2.9 2.7e-05 24.2 0.0 4.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEG44306.1 - 8.2e-07 29.5 0.0 0.017 15.7 0.0 4.9 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEG44306.1 - 0.00012 21.7 0.3 1.6 8.3 0.0 4.5 4 2 0 4 4 4 2 CLASP N terminal DUF3385 PF11865.8 CEG44306.1 - 0.00019 21.4 0.5 1.8 8.5 0.0 5.4 3 2 2 5 5 5 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 CEG44306.1 - 0.0011 17.6 3.1 1.9 6.9 0.0 4.3 3 1 0 4 4 4 2 Adaptin N terminal region RIX1 PF08167.12 CEG44306.1 - 0.0014 18.4 3.8 6.3 6.5 0.0 5.4 7 1 1 8 8 8 2 rRNA processing/ribosome biogenesis Tti2 PF10521.9 CEG44306.1 - 0.0014 18.2 0.0 0.11 12.0 0.0 3.3 2 1 1 3 3 3 1 Tti2 family MMS19_C PF12460.8 CEG44306.1 - 0.0022 17.2 0.1 0.047 12.8 0.1 2.5 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal CTD_bind PF04818.13 CEG44306.1 - 0.0099 16.7 2.5 4.7 8.1 0.0 5.3 5 1 1 6 6 5 1 RNA polymerase II-binding domain. V-ATPase_H_N PF03224.14 CEG44306.1 - 0.041 13.2 0.1 1.9 7.7 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H ParcG PF10274.9 CEG44306.1 - 0.044 13.9 1.2 42 4.2 0.0 4.6 4 2 0 5 5 5 0 Parkin co-regulated protein UPF0253 PF06786.12 CEG44306.1 - 0.048 13.9 0.6 6.7 7.1 0.0 4.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0253) Arm PF00514.23 CEG44306.1 - 0.064 13.3 2.8 1.5 9.0 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Importin_rep_4 PF18808.1 CEG44306.1 - 0.78 10.1 9.7 1.8 8.9 0.1 4.7 3 2 1 4 4 4 0 Importin repeat Glyco_hydro81C PF17652.1 CEG44307.1 - 1.5e-116 389.4 3.7 2e-116 389.1 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain AAA_16 PF13191.6 CEG44308.1 - 1.5e-10 41.7 0.1 1.5e-09 38.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 CEG44308.1 - 3.9e-10 40.3 0.0 1.4e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG44308.1 - 9e-09 35.7 0.0 6.8e-08 32.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_lid_10 PF17872.1 CEG44308.1 - 1.5e-05 25.1 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 CEG44308.1 - 0.0035 17.7 0.1 0.03 14.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEG44308.1 - 0.0081 15.9 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CEG44308.1 - 0.018 14.9 0.2 0.13 12.2 0.0 2.4 2 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 CEG44308.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 CEG44308.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CEG44308.1 - 0.06 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CEG44308.1 - 0.087 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEG44308.1 - 0.09 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CEG44308.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CEG44308.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RPN2_C PF18004.1 CEG44311.1 - 0.26 11.2 3.2 0.87 9.5 3.2 1.8 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RSN1_7TM PF02714.15 CEG44313.1 - 5.1e-43 147.4 19.5 5.1e-43 147.4 19.5 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CEG44313.1 - 6.4e-29 100.7 4.6 6.4e-29 100.7 4.6 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CEG44313.1 - 1.4e-24 87.3 1.5 1.6e-16 61.0 0.2 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHO4 PF01384.20 CEG44314.1 - 0.012 14.6 0.0 0.015 14.3 0.0 1.3 1 1 0 1 1 1 0 Phosphate transporter family DUF475 PF04332.15 CEG44314.1 - 1.2 8.8 6.5 0.61 9.8 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF475) AA_permease_2 PF13520.6 CEG44315.1 - 7.7e-41 140.3 41.5 1e-40 139.9 41.5 1.2 1 0 0 1 1 1 1 Amino acid permease DC_STAMP PF07782.13 CEG44315.1 - 0.15 11.8 1.8 0.52 10.1 1.8 1.9 1 0 0 1 1 1 0 DC-STAMP-like protein zf-C3HC4_2 PF13923.6 CEG44316.1 - 1.9 8.4 12.1 8.8 6.3 7.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Elicitin PF00964.17 CEG44317.1 - 3.4e-07 30.2 0.2 3.4e-07 30.2 0.2 1.6 2 0 0 2 2 2 1 Elicitin LYRIC PF15686.5 CEG44317.1 - 0.058 13.0 0.9 0.077 12.5 0.9 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family JCAD PF15351.6 CEG44317.1 - 0.36 8.6 7.6 0.47 8.2 7.6 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Elicitin PF00964.17 CEG44318.1 - 1.1e-09 38.2 0.2 2.1e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Elicitin Hydrolase_4 PF12146.8 CEG44329.1 - 2.4e-12 46.6 0.0 2.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG44329.1 - 2.3e-08 34.0 0.0 5.2e-06 26.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 CEG44329.1 - 1.8e-05 23.9 0.0 2.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 CEG44329.1 - 4.4e-05 23.4 0.0 0.00041 20.2 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CEG44329.1 - 4.9e-05 23.3 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG44329.1 - 0.00015 22.5 0.0 0.0014 19.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CEG44329.1 - 0.00024 20.7 0.0 0.061 12.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 CEG44329.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) TFIID_30kDa PF03540.13 CEG44330.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit MbeD_MobD PF04899.12 CEG44330.1 - 0.23 11.6 4.3 0.82 9.8 4.3 1.9 1 0 0 1 1 1 0 MbeD/MobD like FANCI_S1-cap PF14674.6 CEG44330.1 - 7.2 6.8 9.3 3.2 7.9 1.2 3.2 2 1 1 3 3 3 0 FANCI solenoid 1 cap DASH_Ask1 PF08655.10 CEG44331.1 - 2.5e-07 30.5 0.1 5.4e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 SAM_2 PF07647.17 CEG44333.1 - 3.2e-07 30.4 0.6 8.9e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEG44333.1 - 2.2e-06 28.0 0.1 5.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-TRAF PF02176.18 CEG44333.1 - 0.00013 22.5 59.9 0.00041 21.0 1.3 7.1 4 2 3 7 7 7 4 TRAF-type zinc finger SAM_PNT PF02198.16 CEG44333.1 - 0.037 14.0 0.3 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain CENP-B_dimeris PF09026.10 CEG44333.1 - 0.72 10.3 15.3 0.042 14.2 8.0 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain HATPase_c_3 PF13589.6 CEG44334.1 - 1.3e-11 44.5 0.0 2.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CEG44334.1 - 3.7e-09 36.5 0.0 6.1e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 CEG44334.1 - 4.7e-05 23.8 0.0 0.00025 21.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCK PF07802.11 CEG44335.1 - 0.0002 21.7 1.5 0.00042 20.7 1.5 1.5 1 0 0 1 1 1 1 GCK domain Rhodanese PF00581.20 CEG44337.1 - 0.0097 16.4 0.0 0.028 14.9 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain Ribosomal_S9 PF00380.19 CEG44341.1 - 1.9e-48 164.0 1.2 3.1e-48 163.3 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Snf7 PF03357.21 CEG44342.1 - 1e-39 135.9 20.0 1e-39 135.9 20.0 2.0 1 1 1 2 2 2 1 Snf7 SYF2 PF08231.12 CEG44342.1 - 0.036 14.5 4.8 0.047 14.1 4.8 1.2 1 0 0 1 1 1 0 SYF2 splicing factor DUF948 PF06103.11 CEG44342.1 - 0.06 13.6 2.9 2.1 8.7 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC24 PF15669.5 CEG44342.1 - 0.13 12.1 9.0 0.021 14.7 4.1 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Baculo_F PF12259.8 CEG44342.1 - 2.9 6.3 8.5 5 5.5 8.5 1.3 1 1 0 1 1 1 0 Baculovirus F protein Glycos_transf_2 PF00535.26 CEG44343.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 SCIMP PF15050.6 CEG44343.1 - 0.17 12.4 0.5 0.41 11.1 0.5 1.6 1 0 0 1 1 1 0 SCIMP protein WD40 PF00400.32 CEG44344.1 - 2e-25 88.5 19.2 8.2e-05 23.3 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG44344.1 - 1.7e-10 41.0 2.6 0.00014 22.1 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG44344.1 - 0.00043 20.2 1.6 0.009 15.9 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEG44344.1 - 0.0034 16.4 2.2 1.9 7.4 0.0 4.1 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PEN-2 PF10251.9 CEG44345.1 - 3.6e-17 62.5 2.8 4.5e-17 62.2 2.8 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase PIG-S PF10510.9 CEG44347.1 - 1.6e-98 330.8 5.0 1.6e-98 330.8 5.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein CRAL_TRIO PF00650.20 CEG44348.1 - 4.4e-16 59.0 0.0 5.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEG44348.1 - 6.7e-05 23.1 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LRR_8 PF13855.6 CEG44349.1 - 0.012 15.4 0.1 10 6.0 0.5 3.4 2 1 0 2 2 2 0 Leucine rich repeat SP_C-Propep PF08999.10 CEG44349.1 - 0.091 12.6 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Conotoxin PF02950.17 CEG44350.1 - 2.5 9.2 5.0 77 4.4 4.5 2.3 1 1 0 1 1 1 0 Conotoxin MPC PF03650.13 CEG44351.1 - 4.9e-36 123.2 1.4 7.5e-36 122.6 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Nup35_RRM PF05172.13 CEG44351.1 - 8.1e-20 70.7 0.0 2.2e-19 69.3 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CEG44351.1 - 7.3e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pex14_N PF04695.13 CEG44353.1 - 7.1e-17 62.5 0.1 7.1e-17 62.5 0.1 3.4 3 1 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region PUB PF09409.10 CEG44353.1 - 1.7e-14 53.5 0.0 4.5e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 PUB domain DUF5572 PF17733.1 CEG44353.1 - 3.3e-11 42.9 0.5 1.1e-10 41.2 0.5 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5572) Pro-kuma_activ PF09286.11 CEG44353.1 - 0.26 11.6 3.4 0.69 10.2 0.7 2.8 2 1 1 3 3 3 0 Pro-kumamolisin, activation domain HTH_19 PF12844.7 CEG44353.1 - 1 9.4 3.2 34 4.6 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Bacillus_HBL PF05791.11 CEG44353.1 - 3.4 7.5 17.1 15 5.4 11.4 3.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Cyclin_N PF00134.23 CEG44354.1 - 1e-12 47.9 0.0 2.9e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CEG44354.1 - 0.012 15.6 2.5 0.014 15.4 0.4 2.3 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Imm3 PF14425.6 CEG44354.1 - 0.017 15.1 0.6 0.031 14.3 0.6 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 fn3 PF00041.21 CEG44358.1 - 0.027 14.8 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain PT-VENN PF04829.13 CEG44358.1 - 1.6 8.9 4.0 0.5 10.5 0.9 1.8 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DUF4407 PF14362.6 CEG44360.1 - 0.31 10.3 9.7 0.64 9.3 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 CEG44362.1 - 5e-52 176.9 0.0 6.2e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44362.1 - 1.6e-32 112.9 0.0 3e-32 111.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG44362.1 - 6.1e-06 25.8 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG44362.1 - 9.5e-06 24.6 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG44362.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG44362.1 - 0.019 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG44362.1 - 0.031 14.2 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEG44362.1 - 0.036 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF2269 PF10027.9 CEG44362.1 - 0.11 12.6 0.6 15 5.6 0.3 2.9 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) F-box PF00646.33 CEG44364.1 - 0.012 15.5 0.1 0.055 13.4 0.1 2.2 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 CEG44364.1 - 0.028 14.3 5.9 0.16 11.9 0.1 3.1 3 0 0 3 3 3 0 F-box-like PRANC PF09372.10 CEG44364.1 - 0.039 14.3 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 PRANC domain HMA PF00403.26 CEG44365.1 - 7.8e-12 45.5 0.7 9.5e-12 45.2 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Sld5 PF05916.11 CEG44368.1 - 0.007 16.8 0.1 0.011 16.1 0.1 1.3 1 1 0 1 1 1 1 GINS complex protein IF-2B PF01008.17 CEG44368.1 - 0.023 13.9 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family NRN1 PF15056.6 CEG44368.1 - 0.027 14.6 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Neuritin protein family PSD4 PF07631.11 CEG44368.1 - 0.051 14.1 0.0 0.071 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) RGI_lyase PF18370.1 CEG44368.1 - 0.086 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain HECT PF00632.25 CEG44370.1 - 1.9e-82 277.2 0.0 2.7e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C92 PF05708.12 CEG44371.1 - 0.00038 20.6 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Isochorismatase PF00857.20 CEG44371.1 - 0.0086 16.3 0.1 0.059 13.5 0.1 2.5 2 1 0 2 2 2 1 Isochorismatase family DeoRC PF00455.22 CEG44371.1 - 0.042 13.8 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 DeoR C terminal sensor domain Clathrin PF00637.20 CEG44372.1 - 2.3e-183 601.4 36.8 5.7e-32 110.6 0.2 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CEG44372.1 - 1.8e-29 101.4 0.4 6e-29 99.8 0.4 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 CEG44372.1 - 4.8e-15 55.0 0.7 0.0034 17.6 0.0 5.8 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 CEG44372.1 - 1.3e-06 27.6 0.1 3.9e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 CEG44372.1 - 3.9e-06 26.5 2.4 1.6 8.6 0.1 5.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44372.1 - 6.6e-05 22.7 9.4 1.8 8.8 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CEG44372.1 - 0.0007 18.8 3.2 0.42 9.6 0.1 3.5 3 0 0 3 3 3 2 Coatomer WD associated region ANAPC3 PF12895.7 CEG44372.1 - 0.00095 19.3 4.8 1.2 9.4 0.1 4.4 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CEG44372.1 - 0.0014 19.3 3.1 1.5e+02 3.6 0.0 8.0 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44372.1 - 0.0056 16.6 8.9 3 8.1 0.1 6.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44372.1 - 0.68 10.3 9.4 15 6.0 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Trns_repr_metal PF02583.17 CEG44373.1 - 0.13 12.6 0.0 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor DDA1 PF10172.9 CEG44374.1 - 9.1e-12 45.1 0.7 2.1e-11 43.9 0.1 1.8 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase PET117 PF15786.5 CEG44374.1 - 0.0051 17.0 2.4 0.022 15.0 3.0 1.7 2 0 0 2 2 2 1 PET assembly of cytochrome c oxidase, mitochondrial PIG-F PF06699.11 CEG44375.1 - 4.9e-36 124.6 16.8 2.4e-35 122.3 16.7 1.8 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF3938 PF13074.6 CEG44375.1 - 0.038 14.2 2.3 0.083 13.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF2062 PF09835.9 CEG44375.1 - 0.34 10.8 8.3 2 8.2 8.5 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Gly-zipper_YMGG PF13441.6 CEG44375.1 - 0.83 9.4 5.7 7.5 6.4 0.3 3.0 3 0 0 3 3 3 0 YMGG-like Gly-zipper DUF3021 PF11457.8 CEG44375.1 - 1.1 9.6 10.7 1.3 9.3 7.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF2530 PF10745.9 CEG44375.1 - 1.4 9.2 10.6 2.2 8.6 0.5 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2530) DUF3677 PF12432.8 CEG44376.1 - 1.9e-08 34.5 0.2 9.5e-08 32.3 0.2 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) Choline_transpo PF04515.12 CEG44377.1 - 2.3e-34 119.1 26.8 3.6e-33 115.2 27.8 2.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF2007 PF09413.10 CEG44377.1 - 0.18 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Cupin_1 PF00190.22 CEG44378.1 - 0.043 13.4 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Dynein_light PF01221.18 CEG44379.1 - 8e-24 83.8 0.2 8e-24 83.8 0.2 1.4 2 0 0 2 2 2 1 Dynein light chain type 1 Ets PF00178.22 CEG44380.1 - 0.038 14.5 0.1 0.077 13.5 0.0 1.5 1 1 1 2 2 2 0 Ets-domain NusA_N PF08529.11 CEG44380.1 - 0.04 14.3 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 NusA N-terminal domain Imm71 PF15602.6 CEG44381.1 - 0.036 14.1 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 71 PH PF00169.29 CEG44381.1 - 0.042 14.4 0.6 0.19 12.2 0.6 2.2 1 1 0 1 1 1 0 PH domain Glucosamine_iso PF01182.20 CEG44382.1 - 4.7e-69 232.7 0.0 5.3e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_M3 PF01432.20 CEG44383.1 - 3e-140 468.5 1.7 5.2e-140 467.7 1.7 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CEG44383.1 - 0.17 11.5 0.2 0.39 10.3 0.2 1.5 1 0 0 1 1 1 0 Peptidase M50B-like CcmD PF04995.14 CEG44383.1 - 0.36 11.0 1.3 0.56 10.3 0.2 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) AAA PF00004.29 CEG44384.1 - 2.1e-52 177.1 0.1 5.3e-41 140.1 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG44384.1 - 8.7e-11 42.5 0.1 0.0011 19.4 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CEG44384.1 - 2e-10 40.3 0.2 9.9e-10 38.1 0.0 2.4 2 1 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CEG44384.1 - 2e-09 37.6 0.0 0.00037 20.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CEG44384.1 - 1.6e-07 30.9 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 CEG44384.1 - 3.8e-07 30.4 0.0 3.1e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEG44384.1 - 4e-07 30.4 3.4 0.0096 16.2 0.4 4.3 2 2 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CEG44384.1 - 2.2e-06 27.5 0.0 0.041 13.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CEG44384.1 - 1.1e-05 25.2 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 CEG44384.1 - 3.5e-05 23.1 0.0 0.4 9.8 0.0 3.5 3 0 0 3 3 3 2 NB-ARC domain TsaE PF02367.17 CEG44384.1 - 4.7e-05 23.4 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CEG44384.1 - 5.4e-05 23.5 0.0 0.039 14.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 CEG44384.1 - 5.9e-05 23.1 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CEG44384.1 - 6.3e-05 23.5 0.1 0.0041 17.6 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 CEG44384.1 - 8.7e-05 22.7 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEG44384.1 - 0.00011 22.2 0.2 0.15 12.0 0.1 3.0 2 1 0 2 2 2 1 NACHT domain TniB PF05621.11 CEG44384.1 - 0.00013 21.4 0.1 1.4 8.2 0.0 3.5 2 1 1 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 CEG44384.1 - 0.00014 21.3 0.3 0.0039 16.6 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CEG44384.1 - 0.00026 21.0 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CEG44384.1 - 0.00041 19.7 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 CEG44384.1 - 0.00064 19.3 0.0 0.065 12.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEG44384.1 - 0.00095 18.9 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CEG44384.1 - 0.0014 18.1 0.0 0.03 13.7 0.0 2.4 2 0 0 2 2 2 1 KaiC ATPase_2 PF01637.18 CEG44384.1 - 0.0019 18.1 1.0 2.9 7.7 0.2 3.7 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CEG44384.1 - 0.0021 17.8 0.0 0.31 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG44384.1 - 0.0039 16.8 2.0 3.9 7.0 0.0 3.6 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 CEG44384.1 - 0.0048 16.1 0.0 0.54 9.4 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF815) ResIII PF04851.15 CEG44384.1 - 0.0095 16.0 0.0 0.83 9.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CEG44384.1 - 0.013 16.1 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CEG44384.1 - 0.013 14.9 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.6 CEG44384.1 - 0.018 15.2 0.0 13 5.9 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 CEG44384.1 - 0.019 15.5 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEG44384.1 - 0.022 14.5 0.1 0.67 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CEG44384.1 - 0.067 13.5 0.0 1.6 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.11 CEG44384.1 - 0.1 12.5 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CEG44384.1 - 0.11 12.3 0.1 46 3.7 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CEG44384.1 - 0.15 12.3 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CEG44384.1 - 0.16 11.0 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RPEL PF02755.15 CEG44385.1 - 1.5e-16 59.5 18.7 0.0002 20.9 0.1 5.8 5 0 0 5 5 5 5 RPEL repeat DUF5045 PF16464.5 CEG44385.1 - 0.46 10.8 2.8 12 6.3 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5045) DUF1543 PF07566.12 CEG44385.1 - 1.2 9.0 3.5 6.2 6.6 0.0 3.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1543) Met_10 PF02475.16 CEG44389.1 - 0.13 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF445 PF04286.12 CEG44389.1 - 0.15 11.8 10.6 0.29 10.9 10.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PTPlike_phytase PF14566.6 CEG44389.1 - 0.46 10.6 3.7 1.8 8.7 3.7 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate CLTH PF10607.9 CEG44389.1 - 7.1 6.5 8.1 24 4.8 8.1 1.9 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Pkinase PF00069.25 CEG44392.1 - 4.1e-74 249.3 0.0 6.1e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44392.1 - 1.2e-34 119.8 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CEG44392.1 - 3.7e-25 85.6 4.8 1.3e-07 30.6 0.3 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG44392.1 - 6.5e-25 87.4 0.5 1.9e-11 44.2 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG44392.1 - 5.5e-21 72.7 2.8 4.1e-05 23.2 0.0 4.9 5 0 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG44392.1 - 2.8e-19 68.7 7.3 3.8e-09 36.3 0.4 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEG44392.1 - 7.5e-17 60.0 2.4 8.6e-05 21.9 0.3 4.6 4 0 0 4 4 4 4 EF hand Kdo PF06293.14 CEG44392.1 - 7.2e-08 32.0 0.1 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 CEG44392.1 - 2e-06 28.0 0.3 0.0037 17.6 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain APH PF01636.23 CEG44392.1 - 0.00024 21.1 0.0 0.0018 18.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 CEG44392.1 - 0.0011 19.3 0.0 0.76 10.1 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG44392.1 - 0.0011 18.9 0.6 1.5 8.8 0.0 2.6 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Choline_kinase PF01633.20 CEG44392.1 - 0.0043 16.7 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 CEG44392.1 - 0.099 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AviRa PF11599.8 CEG44392.1 - 0.16 11.4 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Kinase-like PF14531.6 CEG44392.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dockerin_1 PF00404.18 CEG44392.1 - 0.33 11.2 3.9 30 4.9 2.5 3.6 2 1 0 2 2 2 0 Dockerin type I domain RNB PF00773.19 CEG44393.1 - 6.8e-84 282.0 0.0 1.3e-83 281.0 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEG44393.1 - 1.5e-17 63.4 0.0 3.7e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CEG44393.1 - 1.5e-06 28.0 0.0 4.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CEG44393.1 - 0.00072 19.2 0.1 0.0028 17.3 0.1 2.0 1 1 1 2 2 2 1 Ribonuclease B OB domain Rrp44_S1 PF17215.3 CEG44393.1 - 0.045 13.7 0.0 0.39 10.7 0.0 2.5 1 1 0 1 1 1 0 S1 domain zf-ZPR1 PF03367.13 CEG44394.1 - 2.2e-107 355.8 0.0 8.4e-56 188.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrome_C554 PF13435.6 CEG44394.1 - 0.46 11.4 3.4 20 6.2 0.6 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Rubredoxin_2 PF18073.1 CEG44394.1 - 6.6 6.5 9.2 7.5 6.4 0.6 2.9 3 0 0 3 3 3 0 Rubredoxin metal binding domain betaPIX_CC PF16523.5 CEG44395.1 - 0.031 14.1 0.9 0.031 14.1 0.9 3.6 3 1 1 4 4 4 0 betaPIX coiled coil Tweety PF04906.13 CEG44395.1 - 0.22 10.2 2.6 0.43 9.2 2.6 1.4 1 0 0 1 1 1 0 Tweety DUF1664 PF07889.12 CEG44395.1 - 6.6 6.8 7.5 12 5.9 3.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 CEG44396.1 - 2.9 7.2 15.6 8 5.7 15.6 1.7 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CBM_35 PF16990.5 CEG44399.1 - 0.027 14.7 0.0 0.03 14.6 0.0 1.0 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) DUF5634_N PF18672.1 CEG44403.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5634) HDOD PF08668.12 CEG44403.1 - 0.026 14.0 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 HDOD domain DUF5329 PF17263.2 CEG44404.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5329) RXLR PF16810.5 CEG44407.1 - 2.2e-06 28.2 0.1 2.6e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Sulfotransfer_4 PF17784.1 CEG44407.1 - 0.016 15.1 0.1 0.033 14.0 0.1 1.5 1 1 1 2 2 2 0 Sulfotransferase domain Gp_UL130 PF11668.8 CEG44408.1 - 0.097 12.6 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Cystatin PF00031.21 CEG44411.1 - 0.0036 17.5 0.1 0.0061 16.8 0.1 1.5 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CEG44411.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor EFP_N PF08207.12 CEG44414.1 - 6.4e-19 67.7 1.0 1.2e-18 66.9 0.2 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 CEG44414.1 - 1.6e-17 63.0 2.4 3.1e-17 62.0 2.4 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 CEG44414.1 - 1.6e-12 47.3 0.3 3e-12 46.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Endosulfine PF04667.17 CEG44415.1 - 1e-07 32.0 0.2 0.0094 16.1 0.1 2.2 1 1 1 2 2 2 2 cAMP-regulated phosphoprotein/endosulfine conserved region zf-Nse PF11789.8 CEG44416.1 - 1.2e-13 50.7 0.7 2e-13 49.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CEG44416.1 - 2.1e-06 27.7 0.5 3.6e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEG44416.1 - 2.8e-05 23.9 0.8 7e-05 22.6 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 CEG44416.1 - 0.00013 22.1 0.1 0.00039 20.5 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-RING_2 PF13639.6 CEG44416.1 - 0.0016 18.7 0.5 0.0033 17.7 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain Phage_GP20 PF06810.11 CEG44416.1 - 0.0022 17.8 1.2 0.0022 17.8 1.2 2.0 1 1 1 2 2 2 1 Phage minor structural protein GP20 zf-rbx1 PF12678.7 CEG44416.1 - 0.003 17.8 0.1 0.007 16.6 0.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rtf2 PF04641.12 CEG44416.1 - 0.0088 15.4 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger FAM153 PF15722.5 CEG44416.1 - 0.026 14.9 1.5 0.53 10.6 0.1 2.4 2 0 0 2 2 2 0 FAM153 family zf-MIZ PF02891.20 CEG44416.1 - 0.13 12.1 1.1 0.28 10.9 1.1 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger 2-Hacid_dh_C PF02826.19 CEG44418.1 - 3.7e-35 120.9 0.0 5.8e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT PF01842.25 CEG44418.1 - 9.7e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain 2-Hacid_dh PF00389.30 CEG44418.1 - 0.00018 21.2 0.0 0.00053 19.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT_4 PF13291.6 CEG44418.1 - 0.1 13.2 0.1 0.5 11.0 0.0 2.2 2 0 0 2 2 2 0 ACT domain DUF3921 PF13060.6 CEG44418.1 - 0.18 11.9 0.1 0.47 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) TMEM135_C_rich PF15982.5 CEG44419.1 - 6.2e-09 36.6 3.6 7e-09 36.4 1.7 2.1 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 CEG44419.1 - 0.003 17.9 1.2 0.051 14.0 0.0 2.7 2 1 1 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family Papilloma_E5 PF03025.14 CEG44419.1 - 0.2 11.8 3.0 9.8 6.4 0.5 2.7 2 0 0 2 2 2 0 Papillomavirus E5 DUF1279 PF06916.13 CEG44421.1 - 1.2e-14 54.6 2.0 1.6e-13 51.0 2.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) FYVE PF01363.21 CEG44423.1 - 2.1e-08 34.2 5.1 7.3e-08 32.4 5.1 2.0 1 0 0 1 1 1 1 FYVE zinc finger bZIP_1 PF00170.21 CEG44423.1 - 0.19 11.8 0.8 0.41 10.8 0.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor FYVE_2 PF02318.16 CEG44423.1 - 0.26 11.5 5.9 0.94 9.7 5.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-HIT PF04438.16 CEG44423.1 - 1.6 8.7 9.7 4.6 7.2 9.7 1.8 1 0 0 1 1 1 0 HIT zinc finger Mlf1IP PF10248.9 CEG44423.1 - 1.9 8.5 4.5 5.6 6.9 0.1 2.8 3 0 0 3 3 3 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein zf-RING_5 PF14634.6 CEG44423.1 - 5.3 7.1 7.3 12 6.0 7.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Plexin_cytopl PF08337.12 CEG44425.1 - 0.0058 15.3 0.0 0.0078 14.9 0.0 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PLDc_2 PF13091.6 CEG44427.1 - 3.5e-18 65.8 0.1 4.6e-14 52.4 0.1 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEG44427.1 - 1.1e-08 34.9 5.3 8.7e-05 22.5 0.2 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif MFS_1 PF07690.16 CEG44428.1 - 2.7e-39 135.1 23.6 2.7e-39 135.1 23.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG44428.1 - 0.0013 17.7 6.2 0.0013 17.7 6.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 CEG44428.1 - 0.028 13.3 0.2 0.028 13.3 0.2 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF1295 PF06966.12 CEG44430.1 - 8.1e-59 199.0 5.5 1.1e-58 198.6 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CEG44430.1 - 1.8e-09 37.7 1.3 1.8e-09 37.7 1.3 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 CEG44430.1 - 1.1e-05 25.8 0.2 1.1e-05 25.8 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEG44430.1 - 4.7e-05 23.7 0.4 4.7e-05 23.7 0.4 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CEG44430.1 - 0.005 15.6 1.1 0.005 15.6 1.1 1.9 2 1 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family LpxK PF02606.14 CEG44431.1 - 2.3e-53 181.4 2.5 4.6e-37 127.9 0.2 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase APS_kinase PF01583.20 CEG44432.1 - 1e-64 217.2 0.0 1.7e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 CEG44432.1 - 1.7e-56 191.1 0.0 2.7e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 CEG44432.1 - 7.5e-39 133.1 0.2 1.2e-38 132.4 0.2 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 CEG44432.1 - 8.5e-33 113.3 0.0 1.6e-31 109.1 0.0 2.8 3 0 0 3 3 3 1 PUA-like domain AAA_33 PF13671.6 CEG44432.1 - 6.2e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG44432.1 - 0.0015 19.1 0.0 0.0051 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG44432.1 - 0.028 14.7 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG44432.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEG44432.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RF-1 PF00472.20 CEG44433.1 - 1.8e-09 37.5 11.8 1.3e-05 25.1 0.2 2.3 1 1 1 2 2 2 2 RF-1 domain PAXNEB PF05625.11 CEG44434.1 - 1.1e-66 225.5 0.0 1.5e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein HTH_Tnp_Tc5 PF03221.16 CEG44436.1 - 8.5e-07 28.9 0.1 1.5e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4296 PF14129.6 CEG44436.1 - 0.032 14.8 0.3 5.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) VPS9 PF02204.18 CEG44441.1 - 2e-22 79.3 0.0 5.6e-22 77.9 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PH_4 PF15404.6 CEG44441.1 - 0.0022 17.8 0.2 0.0044 16.8 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain MMgT PF10270.9 CEG44442.1 - 2.5e-09 37.4 0.2 2.9e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter RhodobacterPufX PF11511.8 CEG44442.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 Intrinsic membrane protein PufX Sigma_reg_N PF13800.6 CEG44442.1 - 0.13 12.5 0.2 0.4 11.0 0.0 1.7 1 1 1 2 2 2 0 Sigma factor regulator N-terminal HRCT1 PF15758.5 CEG44444.1 - 0.11 13.5 0.1 0.14 13.1 0.1 1.3 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 TPR_1 PF00515.28 CEG44445.1 - 7.4e-20 69.9 19.8 1e-05 25.1 0.1 9.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44445.1 - 1.8e-17 62.0 24.4 0.00025 20.9 0.0 10.5 10 2 2 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44445.1 - 4e-14 51.6 13.1 0.11 12.7 0.0 9.3 8 0 0 8 8 8 4 Tetratricopeptide repeat Sel1 PF08238.12 CEG44445.1 - 1.3e-12 48.0 2.5 0.0018 18.9 0.0 4.9 5 0 0 5 5 4 3 Sel1 repeat TPR_19 PF14559.6 CEG44445.1 - 5.8e-11 42.7 9.0 0.0019 18.7 0.6 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44445.1 - 1.5e-10 41.2 10.4 0.0013 19.0 0.4 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44445.1 - 4.3e-09 36.1 2.4 0.14 12.6 0.0 7.3 5 1 1 6 6 6 1 Tetratricopeptide repeat zf-MYND PF01753.18 CEG44445.1 - 6.1e-09 35.8 10.9 6.1e-09 35.8 10.9 3.2 4 0 0 4 4 2 1 MYND finger TPR_14 PF13428.6 CEG44445.1 - 3.3e-08 33.7 11.5 0.53 11.2 0.1 7.6 7 2 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44445.1 - 3.4e-08 33.1 17.0 2.9e-05 23.7 0.5 7.9 10 0 0 10 10 10 2 TPR repeat TPR_7 PF13176.6 CEG44445.1 - 1.7e-06 27.7 8.1 0.82 9.8 0.0 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44445.1 - 5.4e-06 27.0 15.0 0.013 16.2 0.0 6.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG44445.1 - 9.6e-06 25.7 1.8 0.14 12.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat HEPN_Swt1 PF18731.1 CEG44445.1 - 1.5e-05 25.3 0.2 4.7e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 Swt1-like HEPN Fis1_TPR_C PF14853.6 CEG44445.1 - 8.2e-05 22.6 0.7 0.022 14.8 0.2 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Paf67 PF10255.9 CEG44445.1 - 0.0012 17.9 0.0 0.0043 16.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_10 PF13374.6 CEG44445.1 - 0.0019 18.0 1.9 3 7.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG44445.1 - 0.0021 18.6 8.5 62 4.5 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat MIT PF04212.18 CEG44445.1 - 0.046 13.8 6.8 0.68 10.0 0.2 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CEG44445.1 - 0.7 10.2 7.3 11 6.4 2.1 4.6 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Aa_trans PF01490.18 CEG44447.1 - 9.3e-44 149.8 21.3 1.1e-43 149.5 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FerA PF08165.11 CEG44452.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain DUF1758 PF05585.12 CEG44453.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Bundlin PF05307.11 CEG44453.1 - 2 8.3 5.0 3.8 7.4 5.0 1.5 1 0 0 1 1 1 0 Bundlin DUF222 PF02720.17 CEG44454.1 - 0.089 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) EF-hand_1 PF00036.32 CEG44456.1 - 4e-12 44.8 2.1 0.00011 21.5 0.4 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CEG44456.1 - 6.8e-11 41.2 5.9 0.00057 19.6 0.0 5.2 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 CEG44456.1 - 1.2e-09 37.9 13.1 0.00054 19.7 0.0 5.2 6 1 0 6 6 6 3 EF-hand domain pair EF-hand_7 PF13499.6 CEG44456.1 - 1.2e-08 35.2 7.5 0.015 15.7 0.3 5.2 4 1 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG44456.1 - 3.6e-07 29.4 0.8 0.077 12.5 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CEG44456.1 - 0.032 14.2 0.4 0.38 10.7 0.0 2.6 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand FTO_NTD PF12933.7 CEG44456.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 FTO catalytic domain SPARC_Ca_bdg PF10591.9 CEG44456.1 - 0.15 12.4 0.7 13 6.1 0.0 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region FbpA PF05833.11 CEG44462.1 - 3.5e-13 49.1 0.0 4.7e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) rve PF00665.26 CEG44463.1 - 3.4e-20 72.4 0.0 4.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG44463.1 - 0.00035 20.3 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Dor1 PF04124.12 CEG44467.1 - 1.7e-54 184.8 3.3 3.2e-54 183.9 3.3 1.4 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CEG44467.1 - 2.7e-09 37.1 0.2 5.2e-08 33.0 0.2 2.7 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CEG44467.1 - 1.9e-06 27.9 1.0 1.9e-06 27.9 1.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 CEG44467.1 - 0.00015 21.6 4.4 0.00044 20.1 4.4 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Prefoldin PF02996.17 CEG44467.1 - 0.058 13.3 0.7 0.16 11.9 0.7 1.8 1 0 0 1 1 1 0 Prefoldin subunit Zw10 PF06248.13 CEG44467.1 - 0.061 11.9 7.9 0.13 10.8 7.9 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 PNK3P PF08645.11 CEG44467.1 - 0.12 12.0 2.1 0.11 12.2 0.5 1.7 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Vps54_N PF10475.9 CEG44467.1 - 0.14 11.5 7.2 0.24 10.6 7.2 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex FEZ PF07763.13 CEG44467.1 - 0.17 11.6 6.1 0.071 12.8 1.4 2.4 2 1 1 3 3 3 0 FEZ-like protein Lactamase_B_2 PF12706.7 CEG44468.1 - 1.8e-24 86.4 0.0 6.4e-24 84.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEG44468.1 - 0.00052 20.1 0.1 0.0019 18.2 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily HSP70 PF00012.20 CEG44469.1 - 8.2e-255 846.6 12.6 9.3e-255 846.4 12.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG44469.1 - 3e-15 55.9 0.8 7.2e-14 51.3 0.1 2.5 3 0 0 3 3 3 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 CEG44469.1 - 4.9e-05 22.7 4.9 4.9e-05 22.7 4.9 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 FtsA PF14450.6 CEG44469.1 - 0.00073 19.9 2.0 1.2 9.6 0.0 3.2 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 CEG44469.1 - 0.003 17.3 0.0 0.033 13.9 0.0 2.6 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain HOIP-UBA PF16678.5 CEG44469.1 - 0.0068 16.4 3.1 0.17 11.9 0.0 3.1 3 0 0 3 3 3 1 HOIP UBA domain pair Hydantoinase_A PF01968.18 CEG44469.1 - 0.01 15.1 1.0 0.099 11.9 0.4 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 CEG44469.1 - 0.03 13.6 1.0 0.055 12.7 0.0 1.9 2 0 0 2 2 2 0 StbA protein DnaI_N PF07319.11 CEG44469.1 - 0.075 13.7 0.1 0.39 11.4 0.1 2.3 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus FYVE PF01363.21 CEG44471.1 - 3.2e-08 33.6 12.5 1.8e-07 31.2 12.5 2.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG44471.1 - 5.8e-05 23.3 4.3 0.00013 22.1 4.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-B_box PF00643.24 CEG44471.1 - 0.65 10.2 6.0 2.8 8.2 6.0 2.1 1 0 0 1 1 1 0 B-box zinc finger C1_1 PF00130.22 CEG44471.1 - 1.1 9.2 8.2 0.61 10.0 5.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CEG44472.1 - 1.1e-54 185.6 0.0 2.1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 CEG44472.1 - 1.7e-31 105.4 10.3 4.5e-07 29.0 0.2 4.5 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 CEG44472.1 - 3.9e-31 108.3 0.0 6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 CEG44472.1 - 5.6e-30 103.0 5.7 1.1e-14 54.0 0.4 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CEG44472.1 - 6.9e-30 103.3 6.1 1.3e-15 57.5 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG44472.1 - 1.3e-24 84.0 8.9 2.9e-06 26.7 0.3 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEG44472.1 - 2.6e-22 77.3 8.6 2.9e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEG44472.1 - 6.3e-12 45.6 1.0 0.0001 22.6 0.0 3.9 4 1 1 5 5 4 2 EF-hand domain EF-hand_4 PF12763.7 CEG44472.1 - 1.6e-10 40.8 3.8 2.4e-05 24.2 0.2 3.5 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG44472.1 - 8.1e-09 35.8 0.3 0.0002 21.7 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 CEG44472.1 - 1e-05 25.0 0.1 1.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.18 CEG44472.1 - 0.00038 20.6 2.7 0.11 12.7 0.1 3.7 1 1 2 3 3 3 3 Dockerin type I domain TerB PF05099.13 CEG44472.1 - 0.00078 19.4 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Tellurite resistance protein TerB Choline_kinase PF01633.20 CEG44472.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CEG44472.1 - 0.0079 16.1 0.0 0.11 12.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_11 PF08976.11 CEG44472.1 - 0.057 14.3 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain UPF0154 PF03672.13 CEG44472.1 - 0.095 12.7 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 CEG44472.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Cupin_8 PF13621.6 CEG44474.1 - 2.3e-20 73.4 0.2 7.5e-20 71.7 0.2 1.9 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEG44474.1 - 8.6e-15 55.2 0.0 3.2e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase APH PF01636.23 CEG44474.1 - 5.9e-08 32.9 0.3 0.0036 17.3 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family SAM_1 PF00536.30 CEG44474.1 - 8.2e-08 32.6 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG44474.1 - 0.00021 21.4 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_L7Ae PF01248.26 CEG44475.1 - 6.3e-24 83.5 0.3 1.1e-23 82.8 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2797 PF10977.8 CEG44475.1 - 0.021 14.8 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) NDUF_C2 PF06374.11 CEG44476.1 - 0.0033 17.5 0.0 0.0038 17.3 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Sigma70_ner PF04546.13 CEG44478.1 - 0.028 14.3 1.7 0.72 9.7 1.7 2.1 1 1 0 1 1 1 0 Sigma-70, non-essential region NAPRTase_N PF17767.1 CEG44482.1 - 1e-39 135.8 0.0 1.3e-38 132.2 0.0 2.4 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 CEG44482.1 - 1e-28 99.9 0.0 1.8e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 CEG44482.1 - 3.7e-09 36.6 0.0 6.6e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family TMEM18 PF14770.6 CEG44483.1 - 5.3e-36 123.2 5.3 6.4e-36 122.9 5.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF2085 PF09858.9 CEG44483.1 - 2 8.9 5.3 1.9 9.0 2.9 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) ABC_tran PF00005.27 CEG44488.1 - 8.3e-42 142.9 5.7 4.9e-21 75.7 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CEG44488.1 - 9.8e-23 80.0 6.0 9.8e-23 80.0 6.0 3.1 3 1 1 4 4 2 1 ABC transporter AAA_21 PF13304.6 CEG44488.1 - 9.4e-19 68.3 3.9 0.00011 22.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG44488.1 - 2.8e-13 49.8 2.2 3.9e-05 23.2 0.1 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CEG44488.1 - 8.7e-07 28.9 0.1 0.0019 17.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 CEG44488.1 - 8.7e-06 25.8 0.1 0.02 15.0 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CEG44488.1 - 1.8e-05 24.4 2.0 0.038 13.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 CEG44488.1 - 2.2e-05 23.6 2.7 0.00088 18.3 0.1 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CEG44488.1 - 8.2e-05 22.6 0.3 0.28 11.0 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEG44488.1 - 0.00054 20.2 0.3 0.34 11.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 CEG44488.1 - 0.00077 19.1 0.1 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEG44488.1 - 0.001 19.0 0.2 0.44 10.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 CEG44488.1 - 0.0014 19.2 4.1 1.1 9.8 0.0 4.0 5 0 0 5 5 3 1 AAA domain NB-ARC PF00931.22 CEG44488.1 - 0.0021 17.3 0.1 0.41 9.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.14 CEG44488.1 - 0.0023 17.8 0.1 1.6 8.6 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 CEG44488.1 - 0.0037 17.0 0.7 3.2 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CEG44488.1 - 0.0048 16.9 2.9 0.45 10.6 0.1 3.2 3 1 1 4 4 2 1 AAA domain Zeta_toxin PF06414.12 CEG44488.1 - 0.0096 15.2 0.0 3.3 6.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 CEG44488.1 - 0.012 15.9 0.4 0.9 9.8 0.3 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CEG44488.1 - 0.029 14.8 6.6 1.3 9.4 0.0 3.9 3 1 0 3 3 3 0 AAA ATPase domain ATP-synt_ab PF00006.25 CEG44488.1 - 0.029 14.0 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 CEG44488.1 - 0.032 14.2 1.6 15 5.6 0.1 4.1 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CEG44488.1 - 0.033 14.4 0.7 7.7 6.8 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CEG44488.1 - 0.046 13.4 0.0 9.4 5.8 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 CEG44488.1 - 0.074 13.5 0.0 6.2 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CEG44488.1 - 0.074 12.9 1.1 10 5.9 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CEG44488.1 - 0.075 13.2 6.3 6.2 7.0 0.2 4.0 4 1 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 CEG44488.1 - 0.087 12.7 0.0 12 5.7 0.1 2.7 2 0 0 2 2 2 0 NTPase Gal4_dimer PF03902.13 CEG44488.1 - 0.097 12.8 0.2 0.78 9.9 0.2 2.5 2 0 0 2 2 2 0 Gal4-like dimerisation domain Thymidylate_kin PF02223.17 CEG44488.1 - 0.1 12.3 1.0 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase Tnp_P_element_C PF12596.8 CEG44488.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.6 4 0 0 4 4 1 0 87kDa Transposase AAA_15 PF13175.6 CEG44488.1 - 0.11 12.2 9.2 0.86 9.2 1.5 4.1 4 1 0 4 4 3 0 AAA ATPase domain AAA_13 PF13166.6 CEG44488.1 - 0.11 11.2 0.0 0.11 11.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CEG44488.1 - 0.11 12.5 0.4 4.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CEG44488.1 - 0.11 12.8 0.7 21 5.6 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 CEG44488.1 - 0.17 12.0 3.1 2.3 8.3 0.0 3.6 4 0 0 4 4 4 0 Dynamin family AAA_23 PF13476.6 CEG44488.1 - 0.22 12.0 23.0 0.11 12.9 4.2 4.0 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 CEG44488.1 - 0.27 11.0 1.6 14 5.4 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CEG44488.1 - 0.31 10.1 3.9 22 4.0 0.0 3.0 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 CEG44488.1 - 0.54 10.5 9.6 0.57 10.4 0.0 4.0 4 1 1 5 5 3 0 AAA domain 5_3_exonuc_N PF02739.16 CEG44488.1 - 0.65 9.9 5.2 7.5 6.4 0.1 3.1 3 1 0 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF87 PF01935.17 CEG44488.1 - 1.3 9.0 11.9 0.13 12.3 0.4 3.5 4 0 0 4 4 3 0 Helicase HerA, central domain Tho2 PF11262.8 CEG44490.1 - 0.016 14.5 0.5 0.016 14.5 0.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PKD_channel PF08016.12 CEG44493.1 - 8.7e-12 44.4 5.0 8.7e-12 44.4 5.0 1.6 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 CEG44493.1 - 4.4e-08 32.6 15.0 7.7e-08 31.9 15.0 1.3 1 0 0 1 1 1 1 Ion transport protein PhoLip_ATPase_C PF16212.5 CEG44495.1 - 5.7e-47 160.6 3.9 5.7e-47 160.6 3.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG44495.1 - 3.6e-17 61.8 0.2 8.8e-17 60.6 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEG44495.1 - 3.5e-11 43.0 0.0 9e-10 38.5 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG44495.1 - 3.2e-09 37.4 0.1 0.012 16.0 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG44495.1 - 0.00076 19.0 0.2 0.0051 16.4 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG44495.1 - 0.0026 17.6 0.1 0.0063 16.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_1 PF00515.28 CEG44496.1 - 1.4e-07 31.0 1.0 0.0052 16.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44496.1 - 5.1e-06 26.2 0.5 0.0067 16.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44496.1 - 0.015 15.5 0.5 0.57 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PUF PF00806.19 CEG44497.1 - 6.7e-59 192.4 11.3 7.3e-08 31.7 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CEG44497.1 - 0.00075 19.9 0.5 9.4 6.6 0.0 4.0 2 1 2 4 4 4 3 CPL (NUC119) domain YfcL PF08891.11 CEG44500.1 - 0.17 12.3 2.3 3.8 7.9 0.5 2.7 2 0 0 2 2 2 0 YfcL protein ECR1_N PF14382.6 CEG44501.1 - 3e-13 49.3 0.4 6.3e-13 48.3 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CEG44501.1 - 4.7e-12 46.1 0.0 9.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Tmemb_161AB PF10268.9 CEG44502.1 - 1e-38 133.3 3.2 1.2e-37 129.8 3.2 2.1 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB BatD PF13584.6 CEG44502.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance DUF2681 PF10883.8 CEG44502.1 - 0.043 14.2 1.5 0.11 13.0 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AIRC PF00731.20 CEG44503.1 - 5e-64 214.3 1.1 5e-64 214.3 1.1 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 CEG44503.1 - 4.8e-53 179.2 0.0 1e-52 178.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CEG44503.1 - 7.5e-18 64.0 0.0 2.4e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CEG44503.1 - 5.7e-05 22.7 0.0 0.00025 20.6 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 CEG44503.1 - 0.00076 18.9 0.2 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEG44503.1 - 0.0086 15.4 0.3 0.029 13.7 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CEG44503.1 - 0.01 15.8 0.2 0.034 14.0 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpR_N PF06506.11 CEG44503.1 - 0.041 13.4 0.2 6 6.4 0.0 2.9 3 0 0 3 3 3 0 Propionate catabolism activator Asp-Al_Ex PF06826.12 CEG44503.1 - 0.052 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Predicted Permease Membrane Region XdhC_C PF13478.6 CEG44503.1 - 0.071 13.6 0.2 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.27 CEG44503.1 - 0.085 13.4 0.2 0.53 10.9 0.2 2.3 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase MARVEL PF01284.23 CEG44504.1 - 1.9e-08 34.4 19.0 2.5e-08 34.1 19.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 CEG44504.1 - 7.3e-06 25.8 17.3 1.3e-05 25.0 17.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF588) DUF4390 PF14334.6 CEG44505.1 - 0.09 12.2 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Peroxidase_2 PF01328.17 CEG44508.1 - 3.8e-47 161.2 0.0 4.5e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Carb_anhydrase PF00194.21 CEG44513.1 - 3e-39 135.1 0.0 4.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SPG48 PF14764.6 CEG44516.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking WD40 PF00400.32 CEG44517.1 - 1.4e-07 32.1 0.2 0.02 15.7 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG44517.1 - 0.068 13.5 0.1 3.3 8.1 0.0 3.1 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_2 PF00152.20 CEG44518.1 - 3.4e-99 331.9 0.0 4.2e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEG44518.1 - 1e-10 41.5 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 CEG44518.1 - 7.8e-08 32.4 0.1 1.5e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 GAD domain tRNA-synt_2b PF00587.25 CEG44518.1 - 0.0049 16.9 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CEG44518.1 - 0.032 13.7 0.0 0.81 9.1 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) DLH PF01738.18 CEG44519.1 - 0.0055 16.3 0.8 0.0055 16.3 0.8 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family FLgD_tudor PF13861.6 CEG44519.1 - 0.19 12.0 5.4 63 3.9 5.9 2.6 1 1 0 1 1 1 0 FlgD Tudor-like domain MT0933_antitox PF14013.6 CEG44519.1 - 0.92 9.9 4.3 1 9.7 1.8 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein LEA_4 PF02987.16 CEG44519.1 - 1.2 9.2 7.1 0.45 10.6 2.0 2.5 1 1 2 3 3 3 0 Late embryogenesis abundant protein Peptidase_S68 PF10461.9 CEG44525.1 - 0.061 13.5 0.5 0.061 13.5 0.5 1.9 2 0 0 2 2 2 0 Peptidase S68 SET PF00856.28 CEG44526.1 - 3.7e-19 69.7 0.0 2.4e-18 67.1 0.0 2.5 1 1 0 1 1 1 1 SET domain PHD PF00628.29 CEG44526.1 - 8.5e-12 44.8 17.5 1.7e-09 37.4 4.0 4.5 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 CEG44526.1 - 0.00061 19.3 1.2 0.00061 19.3 1.2 3.3 3 0 0 3 3 3 1 PHD-finger AWS PF17907.1 CEG44526.1 - 0.004 17.2 0.4 0.004 17.2 0.4 4.5 4 0 0 4 4 4 1 AWS domain zf-HC5HC2H_2 PF13832.6 CEG44526.1 - 0.014 15.5 26.8 0.063 13.4 5.6 4.0 1 1 2 3 3 3 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEG44526.1 - 0.95 9.8 36.5 0.081 13.2 6.8 4.4 2 1 2 4 4 4 0 PHD-like zinc-binding domain TUG-UBL1 PF11470.8 CEG44527.1 - 1.3e-18 67.0 0.2 2.4e-17 62.9 0.0 3.1 4 0 0 4 4 4 1 TUG ubiquitin-like domain PUB PF09409.10 CEG44527.1 - 1.3e-15 57.1 0.0 4.9e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 PUB domain UBX PF00789.20 CEG44527.1 - 1.4e-13 50.9 0.0 3.7e-08 33.5 0.0 3.0 2 1 0 2 2 2 2 UBX domain FERM_f0 PF16511.5 CEG44527.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM RA PF00788.23 CEG44527.1 - 0.086 13.5 0.0 1.1 9.9 0.0 2.6 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain TIM PF00121.18 CEG44528.1 - 2.7e-87 292.2 0.8 3.1e-87 292.0 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF5111 PF17138.4 CEG44528.1 - 0.057 13.3 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) AP_endonuc_2 PF01261.24 CEG44528.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Lig_C PF18330.1 CEG44528.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Arm-DNA-bind_3 PF13356.6 CEG44528.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.6 1 1 0 1 1 1 0 Arm DNA-binding domain DNA_pol_A PF00476.20 CEG44529.1 - 1.7e-75 254.4 0.1 2.2e-74 250.8 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 CEG44529.1 - 1.4e-09 37.9 0.0 4.4e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease p450 PF00067.22 CEG44531.1 - 6.6e-72 242.7 1.0 8e-72 242.4 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APAF1_C PF17908.1 CEG44531.1 - 0.035 14.1 0.1 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 APAF-1 helical domain eIF-3_zeta PF05091.12 CEG44532.1 - 0.17 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PSP1 PF04468.12 CEG44535.1 - 1e-28 99.4 5.4 1.6e-28 98.8 5.4 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region ANTH PF07651.16 CEG44536.1 - 0.045 12.7 0.2 0.076 12.0 0.2 1.3 1 0 0 1 1 1 0 ANTH domain CtsR_C PF17727.1 CEG44536.1 - 0.083 13.0 0.2 0.32 11.2 0.2 2.0 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain CAF1A PF12253.8 CEG44537.1 - 3.8e-21 75.0 2.5 3.8e-21 75.0 2.5 3.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A Pinin_SDK_memA PF04696.13 CEG44537.1 - 0.0053 16.8 17.4 0.0053 16.8 17.4 4.6 5 0 0 5 5 5 2 pinin/SDK/memA/ protein conserved region ATP-grasp PF02222.22 CEG44537.1 - 0.014 15.0 0.0 0.24 11.0 0.0 2.5 1 1 0 2 2 2 0 ATP-grasp domain DUF5398 PF17376.2 CEG44539.1 - 0.0023 18.5 0.6 3.5 8.3 0.0 2.5 1 1 1 2 2 2 2 Family of unknown function (DUF5398) PRP1_N PF06424.12 CEG44540.1 - 6.2e-55 185.7 0.2 6.2e-55 185.7 0.2 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CEG44540.1 - 1.2e-28 97.3 22.9 0.0001 22.8 0.0 13.5 7 5 7 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44540.1 - 4.3e-24 84.8 1.8 2e-06 28.2 0.0 9.1 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44540.1 - 2.4e-08 33.5 0.2 13 6.3 0.0 7.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44540.1 - 3.2e-05 24.5 9.6 0.028 15.1 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44540.1 - 0.00022 21.4 0.2 52 4.5 0.1 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44540.1 - 0.0015 18.4 9.9 6.6 7.1 0.0 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44540.1 - 0.0039 17.0 0.4 15 5.6 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEG44540.1 - 0.037 13.7 0.3 0.037 13.7 0.3 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat-like domain Fer4_13 PF13370.6 CEG44540.1 - 0.039 14.5 1.2 16 6.1 0.0 4.1 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Citrate_synt PF00285.21 CEG44540.1 - 0.078 12.0 0.1 0.82 8.7 0.0 2.3 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain FAD_binding_4 PF01565.23 CEG44540.1 - 0.12 12.1 0.2 0.32 10.7 0.2 1.7 1 0 0 1 1 1 0 FAD binding domain UPF0184 PF03670.13 CEG44540.1 - 0.16 12.4 1.4 0.47 10.9 0.3 2.4 3 0 0 3 3 1 0 Uncharacterised protein family (UPF0184) Myb_DNA-binding PF00249.31 CEG44540.1 - 0.17 12.1 0.7 7.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain YkyA PF10368.9 CEG44540.1 - 0.42 10.3 7.9 0.054 13.2 2.7 2.1 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ChAPs PF09295.10 CEG44540.1 - 0.48 9.4 7.7 22 3.9 1.8 3.3 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) ATP-synt_DE PF00401.20 CEG44540.1 - 8.9 6.7 8.9 0.39 11.0 1.0 3.0 3 0 0 3 3 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain IQ PF00612.27 CEG44541.1 - 0.046 13.5 3.6 3.7 7.6 0.4 3.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF1338 PF07063.13 CEG44542.1 - 0.0098 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) V_cholerae_RfbT PF05575.11 CEG44543.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Complex1_LYR PF05347.15 CEG44544.1 - 7e-05 22.8 0.8 7e-05 22.8 0.8 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4298 PF14131.6 CEG44544.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) FerA PF08165.11 CEG44544.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 FerA (NUC095) domain DUF4573 PF15140.6 CEG44545.1 - 0.095 12.5 0.0 1.2 8.9 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) APG5 PF04106.12 CEG44545.1 - 0.17 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 DUF2393 PF09624.10 CEG44546.1 - 0.036 14.1 0.9 0.046 13.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) zf-CCCH PF00642.24 CEG44547.1 - 3e-08 33.4 20.9 7.5e-05 22.5 4.1 4.3 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEG44547.1 - 0.042 14.6 14.5 0.91 10.3 1.2 3.5 1 1 1 3 3 3 0 Torus domain Antifungal_prot PF11402.8 CEG44547.1 - 0.2 11.9 3.5 9.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Antifungal protein Mito_fiss_reg PF05308.11 CEG44547.1 - 3 7.9 8.1 1.9 8.5 4.2 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator LuxQ-periplasm PF09308.10 CEG44550.1 - 0.046 13.2 0.0 0.054 13.0 0.0 1.0 1 0 0 1 1 1 0 LuxQ, periplasmic HipN PF18253.1 CEG44551.1 - 0.2 11.4 0.5 25 4.6 0.1 3.4 4 0 0 4 4 4 0 Hsp70-interacting protein N N-terminal domain EGF_2 PF07974.13 CEG44552.1 - 0.048 14.0 33.4 0.085 13.2 8.0 3.1 3 0 0 3 3 3 0 EGF-like domain Carn_acyltransf PF00755.20 CEG44553.1 - 3.6e-161 537.7 0.3 4.1e-161 537.5 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Trypsin_2 PF13365.6 CEG44554.1 - 6.4e-19 69.3 0.0 2.4e-18 67.5 0.0 2.0 2 1 0 2 2 2 1 Trypsin-like peptidase domain SAM_1 PF00536.30 CEG44554.1 - 2.8e-09 37.3 0.0 5.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypsin PF00089.26 CEG44554.1 - 6.3e-08 32.7 0.1 5.7e-07 29.6 0.1 2.0 1 1 0 1 1 1 1 Trypsin SAM_2 PF07647.17 CEG44554.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_S46 PF10459.9 CEG44554.1 - 0.2 10.2 0.1 5.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase S46 Sulfatase PF00884.23 CEG44555.1 - 5.1e-27 95.1 0.1 7.3e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CEG44555.1 - 6.3e-06 26.0 0.1 9.8e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CEG44555.1 - 1.1e-05 24.3 0.0 1.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) ABC2_membrane PF01061.24 CEG44556.1 - 5.7e-37 127.2 23.0 5.7e-37 127.2 23.0 2.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 CEG44556.1 - 6e-25 88.4 0.1 1e-24 87.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEG44556.1 - 1.4e-07 31.6 0.2 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CEG44556.1 - 6e-06 25.6 18.4 1.4e-05 24.4 18.4 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CEG44556.1 - 0.00092 19.2 0.1 0.004 17.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CEG44556.1 - 0.0027 17.4 0.3 0.0065 16.2 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CEG44556.1 - 0.0037 16.7 0.1 0.061 12.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG44556.1 - 0.0054 17.1 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CEG44556.1 - 0.0082 15.9 0.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 CEG44556.1 - 0.013 16.0 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEG44556.1 - 0.018 15.3 0.2 0.036 14.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CEG44556.1 - 0.018 14.1 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 CEG44556.1 - 0.02 14.5 0.2 0.045 13.3 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CEG44556.1 - 0.023 15.2 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CEG44556.1 - 0.024 13.6 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CEG44556.1 - 0.03 14.6 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEG44556.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEG44556.1 - 0.066 12.9 0.4 0.13 11.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 CEG44556.1 - 0.13 10.9 0.3 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG44556.1 - 0.13 12.7 0.1 0.59 10.6 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF5044 PF16447.5 CEG44556.1 - 0.13 12.1 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) AAA_5 PF07728.14 CEG44556.1 - 0.2 11.6 0.2 0.52 10.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC2_membrane PF01061.24 CEG44559.1 - 4.2e-46 157.0 62.2 2.2e-29 102.4 21.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG44559.1 - 5.8e-13 49.5 12.7 6.6e-08 33.2 0.0 3.9 4 1 0 4 4 4 2 ABC transporter ABC2_membrane_3 PF12698.7 CEG44559.1 - 0.0032 16.6 18.6 0.0032 16.6 18.6 3.9 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CEG44559.1 - 0.0059 16.4 1.5 0.82 9.4 0.9 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF5086 PF16985.5 CEG44560.1 - 0.098 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) Glyco_hydro_72 PF03198.14 CEG44567.1 - 2.1e-48 165.2 0.0 2.8e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase INTS5_C PF14838.6 CEG44568.1 - 5.7e-10 38.5 10.1 1.3e-08 34.0 0.1 3.4 3 1 1 4 4 4 2 Integrator complex subunit 5 C-terminus tRNA-synt_1b PF00579.25 CEG44568.1 - 0.005 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PHF12_MRG_bd PF16737.5 CEG44569.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain Pkinase_Tyr PF07714.17 CEG44570.1 - 5.6e-50 170.0 0.0 8.6e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG44570.1 - 5.8e-49 166.8 0.0 8.5e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CEG44570.1 - 0.078 11.9 0.1 0.17 10.8 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CEG44570.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TEA PF01285.18 CEG44572.1 - 0.35 11.0 5.4 0.1 12.7 2.2 1.8 2 0 0 2 2 2 0 TEA/ATTS domain PHC2_SAM_assoc PF16616.5 CEG44572.1 - 3.7 8.4 9.7 21 5.9 9.7 1.9 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 FAD_binding_6 PF00970.24 CEG44573.1 - 1.3e-24 86.4 0.1 2.3e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 CEG44573.1 - 1.8e-18 66.4 0.0 3.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 CEG44573.1 - 6e-15 55.8 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEG44573.1 - 8.4e-08 32.5 0.1 0.00022 21.4 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain CRAL_TRIO_2 PF13716.6 CEG44573.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain BACK PF07707.15 CEG44574.1 - 0.044 13.9 1.0 21 5.3 0.0 3.5 3 0 0 3 3 3 0 BTB And C-terminal Kelch A_deamin PF02137.18 CEG44576.1 - 7.1e-59 199.9 0.4 2.2e-55 188.4 0.1 2.5 3 0 0 3 3 3 2 Adenosine-deaminase (editase) domain TIP49 PF06068.13 CEG44576.1 - 0.021 14.1 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Cluap1 PF10234.9 CEG44577.1 - 0.0066 15.9 3.5 0.11 11.9 0.4 2.4 1 1 1 2 2 2 2 Clusterin-associated protein-1 zf-B_box PF00643.24 CEG44577.1 - 0.007 16.5 33.4 0.057 13.6 14.9 2.5 2 0 0 2 2 2 2 B-box zinc finger WD40_alt PF14077.6 CEG44577.1 - 0.01 15.7 0.8 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif LOH1CR12 PF10158.9 CEG44577.1 - 0.016 15.2 2.4 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 Tumour suppressor protein APG6_N PF17675.1 CEG44577.1 - 0.15 12.5 5.7 0.1 13.1 0.5 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region C1_4 PF07975.12 CEG44577.1 - 0.56 10.5 19.8 0.051 13.8 6.6 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain DUF4200 PF13863.6 CEG44577.1 - 1.2 9.5 10.1 0.83 10.1 1.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF4795 PF16043.5 CEG44577.1 - 7.9 6.0 11.6 0.32 10.6 5.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) PIP5K PF01504.18 CEG44582.1 - 2.1e-33 115.7 0.3 4.9e-25 88.3 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 CEG44582.1 - 1.2e-06 29.0 0.0 5.3e-06 26.9 0.0 2.3 1 0 0 1 1 1 1 PH domain Pex24p PF06398.11 CEG44582.1 - 0.0024 16.9 2.0 0.0056 15.7 2.0 1.7 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Na_H_Exchanger PF00999.21 CEG44583.1 - 2e-56 191.5 36.8 2.5e-56 191.1 36.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BTB PF00651.31 CEG44584.1 - 6.5e-20 71.4 1.2 1.7e-19 70.1 0.4 2.1 1 1 1 2 2 2 1 BTB/POZ domain FYVE PF01363.21 CEG44584.1 - 2.4e-14 53.2 13.6 5.8e-14 52.0 13.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_10 PF13460.6 CEG44584.1 - 3.6e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CEG44584.1 - 6.1e-09 35.7 0.0 4.6e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEG44584.1 - 4e-06 26.0 0.0 7.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CEG44584.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase HEAT PF02985.22 CEG44584.1 - 0.0032 17.6 1.4 1 9.8 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 CEG44584.1 - 0.015 15.3 0.3 0.06 13.4 0.2 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 CEG44584.1 - 0.039 13.4 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Armadillo-like HEAT_2 PF13646.6 CEG44584.1 - 0.12 12.7 0.1 4.3 7.8 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats FYVE_2 PF02318.16 CEG44584.1 - 0.14 12.4 9.6 0.4 10.9 9.6 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger ADH_zinc_N PF00107.26 CEG44585.1 - 1.7e-23 83.0 0.0 4.5e-23 81.6 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEG44585.1 - 3.2e-14 54.1 0.0 6.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEG44585.1 - 9.4e-09 35.1 0.2 3.6e-07 30.0 0.1 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CEG44585.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain CHZ PF09649.10 CEG44586.1 - 0.024 14.1 0.4 0.053 13.0 0.4 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ Arylsulfotran_N PF17425.2 CEG44587.1 - 0.071 13.1 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain PDEase_I PF00233.19 CEG44590.1 - 4e-63 213.3 0.0 9.6e-63 212.1 0.0 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CEG44590.1 - 7e-09 36.4 0.3 0.0019 18.8 0.1 3.1 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 CEG44590.1 - 0.00014 22.3 0.0 0.16 12.3 0.0 2.9 3 0 0 3 3 3 2 GAF domain DUF5082 PF16888.5 CEG44590.1 - 0.0078 16.5 0.3 0.019 15.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) RabGAP-TBC PF00566.18 CEG44591.1 - 2.2e-35 122.3 5.0 4e-35 121.4 5.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 CEG44591.1 - 1.9e-09 37.6 0.7 4.8e-06 26.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG44591.1 - 2.1e-07 31.4 0.3 5.2e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG44591.1 - 2.3e-07 31.3 0.0 6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEG44591.1 - 5.5e-05 23.4 0.4 0.0046 17.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CEG44591.1 - 0.0053 17.2 4.7 0.13 12.9 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Zip PF02535.22 CEG44592.1 - 4.4e-42 144.5 19.8 2.6e-41 141.9 19.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter RVT_2 PF07727.14 CEG44595.1 - 2e-60 204.4 0.2 2.5e-60 204.1 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 CEG44595.1 - 0.00086 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Chlororespiratory reduction 6 RVT_1 PF00078.27 CEG44595.1 - 0.027 14.0 0.1 0.069 12.7 0.1 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4508 PF14969.6 CEG44597.1 - 0.028 14.7 0.7 0.039 14.2 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) DUF3047 PF11249.8 CEG44599.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) rve PF00665.26 CEG44602.1 - 6.5e-21 74.7 0.1 8.9e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG44602.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEG44602.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Annexin PF00191.20 CEG44603.1 - 1.1e-36 124.6 0.4 2.5e-14 53.1 0.0 3.2 3 0 0 3 3 3 3 Annexin Ist1 PF03398.14 CEG44603.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Abhydro_lipase PF04083.16 CEG44604.1 - 1.4e-17 63.0 0.0 3.5e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEG44604.1 - 6.7e-09 35.8 2.2 1.4e-08 34.8 2.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 CEG44604.1 - 3.6e-05 22.8 0.8 0.03 13.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CEG44604.1 - 0.001 18.4 0.0 0.0098 15.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DnaJ PF00226.31 CEG44605.1 - 1.8e-24 85.6 5.6 1.8e-24 85.6 5.6 1.9 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 CEG44605.1 - 7.8e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CEG44605.1 - 0.00042 20.3 0.1 0.029 14.3 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain BET PF17035.5 CEG44606.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation FYVE PF01363.21 CEG44607.1 - 4.2e-13 49.2 10.3 7.9e-13 48.4 10.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_2 PF07719.17 CEG44607.1 - 2e-12 46.2 1.5 0.0066 16.5 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44607.1 - 1.4e-09 37.5 0.0 0.00088 18.9 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 CEG44607.1 - 4.4e-09 36.4 9.5 0.00077 20.1 0.0 4.5 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44607.1 - 1e-08 34.7 0.1 0.14 12.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44607.1 - 6.1e-08 32.2 0.1 0.004 16.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44607.1 - 6.2e-08 32.5 0.0 0.12 12.8 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44607.1 - 1.6e-07 31.5 4.6 0.0017 18.6 1.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Ank_5 PF13857.6 CEG44607.1 - 3.6e-07 30.3 0.1 0.00032 20.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_16 PF13432.6 CEG44607.1 - 8.8e-07 29.5 16.9 6e-05 23.6 2.9 3.1 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44607.1 - 1.1e-05 25.9 5.8 0.00063 20.2 1.7 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.7 CEG44607.1 - 2.1e-05 25.0 0.0 0.00079 20.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) TPR_7 PF13176.6 CEG44607.1 - 2.2e-05 24.1 3.0 0.032 14.3 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank PF00023.30 CEG44607.1 - 9.6e-05 22.7 1.7 3.6 8.2 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG44607.1 - 0.0013 19.0 0.3 7.8 7.4 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat TPR_10 PF13374.6 CEG44607.1 - 0.0035 17.2 2.2 0.73 9.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG44607.1 - 0.018 15.3 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG44607.1 - 0.055 14.1 2.0 89 4.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CEG44607.1 - 0.46 11.3 0.1 0.46 11.3 0.1 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CEG44607.1 - 0.58 9.7 2.5 1.8 8.1 0.1 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_9 PF13371.6 CEG44607.1 - 0.64 10.2 6.6 7.5 6.8 1.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Carb_anhydrase PF00194.21 CEG44611.1 - 1.9e-37 129.2 0.0 3.7e-37 128.2 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 CEG44613.1 - 9.7e-37 126.9 0.0 1.7e-36 126.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3177 PF11375.8 CEG44614.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) MgtE_N PF03448.17 CEG44618.1 - 0.024 15.2 0.0 0.027 15.1 0.0 1.1 1 0 0 1 1 1 0 MgtE intracellular N domain ORC6 PF05460.13 CEG44619.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SSF PF00474.17 CEG44620.1 - 0.0017 17.3 0.3 0.0018 17.2 0.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Pkinase PF00069.25 CEG44623.1 - 4.7e-62 209.7 0.0 7e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44623.1 - 2.2e-24 86.1 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG44623.1 - 0.0035 16.7 0.1 0.0065 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Vir_act_alpha_C PF10400.9 CEG44623.1 - 0.012 16.2 0.2 0.038 14.7 0.2 1.8 1 0 0 1 1 1 0 Virulence activator alpha C-term Kinase-like PF14531.6 CEG44623.1 - 0.025 13.9 0.0 0.094 12.0 0.0 2.0 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CEG44623.1 - 0.076 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEG44623.1 - 0.12 11.9 0.0 0.81 9.3 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Dicty_CAR PF05462.11 CEG44624.1 - 0.0093 15.1 0.2 0.013 14.6 0.2 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor GBR_NSP5 PF17580.2 CEG44626.1 - 0.017 15.0 9.3 0.51 10.1 0.6 2.9 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 AMPKBI PF04739.15 CEG44626.1 - 0.052 13.8 0.7 0.17 12.1 0.7 1.9 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain YqjK PF13997.6 CEG44626.1 - 9.9 6.5 7.7 4.3 7.7 0.1 3.8 3 0 0 3 3 3 0 YqjK-like protein Med26 PF08711.11 CEG44627.1 - 9e-14 51.2 0.1 2.6e-13 49.8 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain EF-1_beta_acid PF10587.9 CEG44627.1 - 0.0029 18.0 1.4 0.0029 18.0 1.4 4.8 6 0 0 6 6 6 1 Eukaryotic elongation factor 1 beta central acidic region Pox_RNA_pol PF03293.14 CEG44631.1 - 0.021 14.5 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit NADHdh-2_N PF12155.8 CEG44631.1 - 0.033 14.6 0.0 0.039 14.3 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal FYVE PF01363.21 CEG44632.1 - 6.9e-15 54.9 11.3 1.3e-14 54.0 11.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 CEG44632.1 - 2.5 8.3 8.9 4.9 7.4 8.9 1.4 1 0 0 1 1 1 0 B-box zinc finger Pkinase_Tyr PF07714.17 CEG44633.1 - 1.8e-42 145.4 0.0 2.6e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG44633.1 - 3.3e-38 131.6 0.0 5.1e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SF3b1 PF08920.10 CEG44633.1 - 0.029 14.9 0.2 0.084 13.4 0.2 1.8 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 Kinase-like PF14531.6 CEG44633.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Exo_endo_phos_2 PF14529.6 CEG44634.1 - 0.0046 16.8 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase U3snoRNP10 PF12397.8 CEG44634.1 - 0.046 14.1 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 CCT PF06203.14 CEG44640.1 - 0.034 14.2 0.4 0.046 13.8 0.4 1.2 1 0 0 1 1 1 0 CCT motif FAD-SLDH PF12318.8 CEG44641.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.0 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase SKN1 PF03935.15 CEG44643.1 - 3.7e-56 190.6 12.8 4.6e-36 124.3 6.3 5.0 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Nodulin_late PF07127.11 CEG44643.1 - 2.4 8.6 4.6 2.3 8.6 1.0 2.5 2 0 0 2 2 2 0 Late nodulin protein EB PF01683.18 CEG44643.1 - 5.2 7.5 9.1 0.53 10.6 2.3 2.9 3 0 0 3 3 3 0 EB module Orai-1 PF07856.12 CEG44644.1 - 6.2e-06 26.0 0.4 6.2e-06 26.0 0.4 1.5 2 0 0 2 2 2 1 Mediator of CRAC channel activity CnrY PF17524.2 CEG44644.1 - 0.16 12.2 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma factor CnrY AA_kinase PF00696.28 CEG44645.1 - 5.6e-39 134.2 0.1 9.9e-39 133.4 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 CEG44645.1 - 4.5e-23 82.0 0.0 9.5e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT PF01842.25 CEG44645.1 - 3.1e-13 49.2 0.3 1.1e-05 25.1 0.0 3.0 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CEG44645.1 - 3.3e-13 49.2 0.9 6.7e-08 32.2 0.1 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.16 CEG44645.1 - 4.1e-06 27.4 1.4 3.4e-05 24.5 0.0 3.1 4 0 0 4 4 4 1 Homoserine dehydrogenase, NAD binding domain ACT_6 PF13740.6 CEG44645.1 - 0.0039 17.2 1.9 13 5.9 0.0 3.7 3 0 0 3 3 3 1 ACT domain Orai-1 PF07856.12 CEG44646.1 - 4.6e-29 101.3 10.4 6.5e-29 100.8 10.4 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity T4BSS_DotI_IcmL PF11393.8 CEG44646.1 - 0.079 12.4 0.4 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component Synaptobrevin PF00957.21 CEG44648.1 - 0.021 14.6 0.5 0.044 13.6 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin ADK PF00406.22 CEG44650.1 - 2.4e-45 154.3 0.0 2.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG44650.1 - 2.7e-19 69.9 0.0 4.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CEG44650.1 - 1.2e-13 50.7 0.6 3.7e-13 49.2 0.6 1.8 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CEG44650.1 - 0.0005 20.6 0.0 0.00075 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEG44650.1 - 0.0095 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CEG44650.1 - 0.17 12.2 0.2 3.2 8.0 0.0 2.2 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 CEG44650.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEG44650.1 - 0.19 11.1 0.2 0.27 10.6 0.2 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AroM PF07302.11 CEG44651.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 AroM protein DUF627 PF04781.12 CEG44652.1 - 0.041 13.9 4.3 0.31 11.1 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF627) Form_Nir_trans PF01226.17 CEG44655.1 - 0.1 11.9 0.4 0.17 11.2 0.4 1.3 1 0 0 1 1 1 0 Formate/nitrite transporter FYVE PF01363.21 CEG44655.1 - 0.66 10.1 14.0 0.34 11.1 10.7 2.3 2 1 0 2 2 2 0 FYVE zinc finger Prok-RING_2 PF14445.6 CEG44655.1 - 1.4 9.2 7.4 1.6 8.9 6.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Rad50_zn_hook PF04423.14 CEG44655.1 - 2.8 7.8 7.9 5.6 6.9 1.0 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif GbpA_2 PF18416.1 CEG44656.1 - 0.034 14.4 0.2 0.062 13.6 0.2 1.5 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 SRA PF18491.1 CEG44656.1 - 0.087 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 SET and RING associated domain DUF4579 PF15158.6 CEG44656.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4579) GbpA_2 PF18416.1 CEG44657.1 - 0.073 13.4 2.4 0.17 12.2 1.0 2.2 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 ORF_12_N PF18042.1 CEG44657.1 - 0.21 12.0 2.3 6.5 7.2 0.3 2.9 2 1 0 2 2 2 0 ORF 12 gene product N-terminal PNP_UDP_1 PF01048.20 CEG44658.1 - 7.4e-21 74.5 0.0 9.8e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ERAP1_C PF11838.8 CEG44660.1 - 3.1e-11 43.4 0.0 1.7e-07 31.1 0.0 2.0 2 0 0 2 2 2 2 ERAP1-like C-terminal domain PH PF00169.29 CEG44663.1 - 1.8e-12 47.7 0.2 1.2e-11 45.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEG44663.1 - 3.9e-07 30.5 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain GBP PF02263.19 CEG44663.1 - 5.4e-06 25.9 0.2 1.8e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CEG44663.1 - 0.00011 21.7 12.9 0.00022 20.7 12.9 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ATPase_2 PF01637.18 CEG44663.1 - 0.00037 20.5 0.7 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CEG44663.1 - 0.00049 20.2 0.1 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PH_8 PF15409.6 CEG44663.1 - 0.021 15.1 0.0 7.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain AAA_16 PF13191.6 CEG44663.1 - 0.054 13.9 0.2 0.25 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 CEG44663.1 - 0.07 12.3 0.6 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 CEG44663.1 - 0.19 11.8 2.0 1.8 8.6 0.6 2.3 2 0 0 2 2 2 0 Dynamin family YqzH PF14164.6 CEG44663.1 - 0.26 11.4 2.2 0.55 10.3 0.8 2.3 2 0 0 2 2 2 0 YqzH-like protein RCC1 PF00415.18 CEG44664.1 - 3.5e-67 222.8 24.1 1.9e-11 44.4 0.2 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 CEG44664.1 - 2.7e-35 121.1 2.5 2e-23 82.8 0.2 2.8 2 0 0 2 2 2 2 SPRY domain RCC1_2 PF13540.6 CEG44664.1 - 8e-31 105.2 33.8 8.9e-09 34.9 1.3 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CEG44664.1 - 5e-08 32.8 0.6 2.6e-05 23.9 0.2 3.5 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.16 CEG44665.1 - 2.2e-29 102.5 31.5 3.9e-28 98.4 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MPM1 PF17234.2 CEG44673.1 - 0.53 10.5 7.5 0.69 10.2 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 CAP_GLY PF01302.25 CEG44674.1 - 7.9e-05 22.6 0.1 0.0001 22.2 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain rve PF00665.26 CEG44676.1 - 4.7e-20 72.0 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG44676.1 - 1.2e-16 60.3 0.7 2.2e-16 59.4 0.7 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 CEG44676.1 - 8.8e-13 48.7 0.4 5.6e-12 46.1 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEG44676.1 - 2e-09 37.4 0.2 3.8e-08 33.3 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 CEG44676.1 - 6.7e-08 33.0 0.1 2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_29 PF13551.6 CEG44676.1 - 2.3e-06 27.5 0.0 8e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 CEG44676.1 - 2.5e-05 23.9 0.7 0.00017 21.3 0.0 2.7 4 0 0 4 4 4 1 Homeodomain-like domain rve_2 PF13333.6 CEG44676.1 - 0.0074 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CEG44676.1 - 0.041 14.1 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE domain HTH_Tnp_IS630 PF01710.16 CEG44676.1 - 0.043 13.9 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_Tnp_1_2 PF13022.6 CEG44676.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DIM PF08194.12 CEG44677.1 - 0.071 13.3 2.0 0.11 12.7 2.0 1.3 1 0 0 1 1 1 0 DIM protein Putative_PNPOx PF01243.20 CEG44678.1 - 0.012 15.7 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PTPA PF03095.15 CEG44679.1 - 7e-116 386.9 0.0 8.2e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein ABC_tran PF00005.27 CEG44680.1 - 6.4e-49 166.0 0.0 7.7e-25 88.0 0.0 3.8 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CEG44680.1 - 4.8e-18 66.0 0.1 3.6e-05 23.7 0.0 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG44680.1 - 2.9e-15 56.3 0.0 0.00023 20.7 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG44680.1 - 2.2e-10 41.4 1.5 0.0033 17.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CEG44680.1 - 8.4e-07 28.6 0.1 0.058 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CEG44680.1 - 1.1e-06 29.0 0.0 0.064 13.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEG44680.1 - 3.1e-06 27.5 0.1 0.19 12.0 0.1 3.7 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CEG44680.1 - 3.2e-06 27.2 0.1 0.031 14.3 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG44680.1 - 8.6e-06 25.8 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CEG44680.1 - 1.7e-05 25.3 0.0 0.095 13.1 0.0 3.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEG44680.1 - 1.7e-05 25.2 0.1 0.37 11.2 0.0 3.6 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 CEG44680.1 - 5e-05 23.3 0.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CEG44680.1 - 7.3e-05 23.2 0.1 0.22 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 CEG44680.1 - 7.4e-05 23.3 6.0 0.19 12.3 0.0 4.0 4 0 0 4 4 2 2 AAA domain AAA_15 PF13175.6 CEG44680.1 - 7.9e-05 22.5 4.0 0.11 12.2 0.0 4.2 5 0 0 5 5 4 1 AAA ATPase domain Chromo PF00385.24 CEG44680.1 - 8.5e-05 22.4 3.0 8.5e-05 22.4 3.0 2.2 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.6 CEG44680.1 - 0.00013 22.1 0.0 1 9.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 CEG44680.1 - 0.0002 21.4 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_27 PF13514.6 CEG44680.1 - 0.0002 21.0 0.2 0.097 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain Vac14_Fab1_bd PF12755.7 CEG44680.1 - 0.00034 21.1 0.0 0.45 11.2 0.0 2.9 3 0 0 3 3 2 1 Vacuolar 14 Fab1-binding region SbcCD_C PF13558.6 CEG44680.1 - 0.00068 19.8 0.1 0.14 12.4 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CEG44680.1 - 0.0011 19.1 0.6 0.61 10.1 0.1 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain MeaB PF03308.16 CEG44680.1 - 0.0013 17.8 0.2 1 8.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CEG44680.1 - 0.0025 17.0 0.0 0.19 10.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain CLASP_N PF12348.8 CEG44680.1 - 0.0027 17.3 0.1 0.023 14.2 0.1 2.3 1 1 0 1 1 1 1 CLASP N terminal G-alpha PF00503.20 CEG44680.1 - 0.0028 16.9 0.1 2.8 7.0 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 CEG44680.1 - 0.0033 17.2 0.1 0.71 9.6 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEG44680.1 - 0.0053 16.3 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CEG44680.1 - 0.0078 15.9 0.0 4 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CEG44680.1 - 0.01 15.9 0.0 3.2 7.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CEG44680.1 - 0.027 14.2 0.4 4 7.1 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase PduV-EutP PF10662.9 CEG44680.1 - 0.029 14.1 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 CEG44680.1 - 0.033 13.4 0.0 6 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CEG44680.1 - 0.043 13.7 0.1 15 5.5 0.1 3.4 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 CEG44680.1 - 0.052 13.2 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 CEG44680.1 - 0.052 12.9 0.0 12 5.2 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FliE PF02049.18 CEG44680.1 - 0.053 13.7 0.2 0.053 13.7 0.2 2.3 2 0 0 2 2 1 0 Flagellar hook-basal body complex protein FliE ABC_tran_Xtn PF12848.7 CEG44680.1 - 0.054 13.5 0.4 0.054 13.5 0.4 2.7 2 0 0 2 2 1 0 ABC transporter Dynamin_N PF00350.23 CEG44680.1 - 0.068 13.2 3.5 0.58 10.2 0.0 3.4 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 CEG44680.1 - 0.068 13.4 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CEG44680.1 - 0.073 13.1 0.0 9.6 6.2 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CEG44680.1 - 0.082 12.9 0.2 14 5.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CEG44680.1 - 0.1 12.5 9.5 0.8 9.6 0.0 4.3 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea PRK PF00485.18 CEG44680.1 - 0.11 12.3 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 CEG44680.1 - 0.12 12.0 0.0 24 4.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 CEG44680.1 - 0.16 11.8 0.0 15 5.3 0.0 2.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 CEG44680.1 - 0.37 10.5 1.6 28 4.4 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein Glycohydro_20b2 PF14845.6 CEG44680.1 - 1.7 9.3 3.6 7.8 7.2 0.3 2.6 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like IMS PF00817.20 CEG44681.1 - 3.8e-41 140.6 0.3 1.4e-40 138.7 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CEG44681.1 - 1.4e-12 48.3 0.4 4.5e-12 46.7 0.4 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEG44681.1 - 0.0019 18.4 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif UBZ_FAAP20 PF15750.5 CEG44681.1 - 0.0044 16.9 0.7 1.6 8.8 0.3 3.0 2 0 0 2 2 2 1 Ubiquitin-binding zinc-finger IML1 PF12257.8 CEG44681.1 - 0.028 13.5 0.5 1.8 7.6 0.3 2.3 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 zf-C2H2_4 PF13894.6 CEG44681.1 - 0.44 11.5 3.0 33 5.7 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger RecR PF02132.15 CEG44681.1 - 0.49 10.0 3.5 8.1 6.1 0.4 3.0 2 0 0 2 2 2 0 RecR protein Lar_restr_allev PF14354.6 CEG44681.1 - 0.93 9.9 4.9 12 6.3 0.1 2.9 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 CEG44681.1 - 6.5 6.3 7.6 12 5.5 1.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Y_phosphatase2 PF03162.13 CEG44682.1 - 7.1e-43 146.0 0.0 9.4e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEG44682.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CEG44682.1 - 0.003 17.6 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CEG44682.1 - 0.023 14.5 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MAT1 PF06391.13 CEG44682.1 - 0.16 11.8 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 zf-RING_2 PF13639.6 CEG44683.1 - 9.2e-09 35.5 13.8 9.2e-09 35.5 13.8 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG44683.1 - 1.7e-07 31.4 10.3 3.3e-07 30.5 10.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG44683.1 - 0.00013 21.8 14.0 0.00023 21.0 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG44683.1 - 0.00013 21.9 7.6 0.00027 20.9 7.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEG44683.1 - 0.00014 21.5 11.5 0.00014 21.5 11.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEG44683.1 - 0.028 14.3 15.5 0.084 12.7 15.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CEG44683.1 - 0.037 14.1 13.3 0.079 13.1 13.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RVT PF13966.6 CEG44683.1 - 0.05 14.3 3.1 1.2 9.9 0.9 2.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Prok-RING_4 PF14447.6 CEG44683.1 - 0.16 11.8 9.8 0.37 10.7 9.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CEG44683.1 - 1.1 9.4 12.4 2.8 8.2 12.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CEG44683.1 - 4.6 7.1 15.2 1.3 8.9 11.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1178 PF06676.11 CEG44683.1 - 5.2 7.4 7.1 0.9 9.9 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Glyco_hydro_3 PF00933.21 CEG44684.1 - 8.7e-57 192.9 0.0 1.2e-56 192.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEG44684.1 - 8.2e-41 140.2 0.0 1.9e-40 139.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CEG44684.1 - 1.5e-12 47.4 0.0 3.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Aha1_N PF09229.11 CEG44686.1 - 1.5e-21 77.0 3.9 1.9e-21 76.7 0.6 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal zf-MYND PF01753.18 CEG44686.1 - 3.2e-09 36.7 14.7 5.2e-09 36.1 14.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CEG44686.1 - 0.02 15.2 13.8 0.037 14.3 13.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SR-25 PF10500.9 CEG44686.1 - 0.041 13.5 7.9 0.058 13.0 7.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PolC_DP2 PF03833.13 CEG44686.1 - 0.069 11.0 5.6 0.094 10.6 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Indigoidine_A PF04227.12 CEG44687.1 - 6.7e-122 406.4 0.6 1.1e-121 405.7 0.6 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CEG44687.1 - 7.2e-28 97.8 0.3 7.5e-16 58.3 0.0 3.2 3 0 0 3 3 3 3 pfkB family carbohydrate kinase EF-hand_6 PF13405.6 CEG44689.1 - 0.0061 16.4 0.0 0.35 10.9 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CEG44689.1 - 0.058 13.8 3.4 0.14 12.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_14 PF17959.1 CEG44689.1 - 0.16 12.3 0.0 0.16 12.3 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain TBCA PF02970.16 CEG44689.1 - 1.8 9.0 8.5 0.34 11.3 0.6 2.6 2 0 0 2 2 2 0 Tubulin binding cofactor A GPI2 PF06432.11 CEG44691.1 - 1.9e-76 257.2 11.0 2.2e-76 257.0 11.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Col_cuticle_N PF01484.17 CEG44691.1 - 0.061 13.4 2.4 0.27 11.3 0.1 3.3 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain FA_desaturase PF00487.24 CEG44691.1 - 8.4 6.1 12.9 1.6 8.5 4.9 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Myb_DNA-binding PF00249.31 CEG44693.1 - 4.5e-11 42.8 0.2 9.7e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG44693.1 - 0.066 13.5 0.4 0.16 12.2 0.4 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain tRNA_int_end_N2 PF12928.7 CEG44694.1 - 7.8e-06 26.0 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 CEG44694.1 - 0.035 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain JmjC PF02373.22 CEG44695.1 - 1.1e-39 135.4 0.1 2.7e-39 134.1 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CEG44695.1 - 2.4e-10 40.2 0.5 7e-10 38.7 0.5 1.9 1 0 0 1 1 1 1 jmjN domain PHD_4 PF16866.5 CEG44695.1 - 0.18 11.9 12.1 0.099 12.7 9.3 2.1 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 CEG44695.1 - 0.22 11.5 9.5 0.81 9.6 9.5 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CEG44695.1 - 0.22 11.4 10.9 0.54 10.2 10.9 1.7 1 0 0 1 1 1 0 PHD-finger Arf PF00025.21 CEG44697.1 - 2.6e-59 199.6 0.5 2e-45 154.4 0.1 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CEG44697.1 - 1.5e-10 41.3 0.1 4e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEG44697.1 - 1.4e-09 37.6 0.1 7.2e-06 25.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEG44697.1 - 1.3e-07 31.3 0.6 0.0013 18.2 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 CEG44697.1 - 5.5e-07 29.3 0.1 2e-05 24.3 0.0 1.9 1 1 1 2 2 2 2 Ras family MMR_HSR1 PF01926.23 CEG44697.1 - 3.9e-05 23.7 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEG44697.1 - 0.0037 16.6 0.1 0.075 12.4 0.0 2.1 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 CEG44697.1 - 0.02 15.5 0.0 0.026 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CEG44697.1 - 0.03 13.9 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B MeaB PF03308.16 CEG44697.1 - 0.046 12.7 0.7 1.7 7.6 0.6 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CEG44697.1 - 0.049 14.1 0.1 0.1 13.1 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Ints3 PF10189.9 CEG44698.1 - 4.2e-73 245.4 0.6 4.2e-73 245.4 0.6 2.3 2 0 0 2 2 2 1 Integrator complex subunit 3 LRR_6 PF13516.6 CEG44699.1 - 4.4e-08 32.6 0.2 0.014 15.4 0.0 5.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.7 CEG44699.1 - 1e-05 25.8 0.7 0.5 10.9 0.3 5.1 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG44699.1 - 0.0005 20.3 1.9 59 4.8 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat DUF3492 PF11997.8 CEG44699.1 - 0.048 13.4 0.0 0.08 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) DUF1699 PF08004.11 CEG44699.1 - 0.099 12.3 0.2 4 7.1 0.0 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1699) CitMHS PF03600.16 CEG44700.1 - 1e-31 110.3 63.8 9.1e-28 97.3 38.1 1.8 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CEG44700.1 - 3.6e-30 105.4 41.5 5.1e-30 104.9 41.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 CEG44700.1 - 4.5e-27 96.0 11.4 6.4e-12 46.1 0.2 3.1 1 1 2 3 3 3 3 SPX domain Vps52 PF04129.12 CEG44701.1 - 4.6e-119 398.5 15.8 4.6e-119 398.5 15.8 2.2 2 1 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 CEG44701.1 - 7e-09 34.6 8.3 7e-09 34.6 8.3 2.1 1 1 0 2 2 2 1 Exocyst complex component Sec3 NUC130_3NT PF08158.12 CEG44701.1 - 0.096 13.0 0.2 1.2 9.5 0.0 3.0 2 0 0 2 2 2 0 NUC130/3NT domain DUF1722 PF08349.11 CEG44701.1 - 0.13 12.5 2.4 0.28 11.5 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1722) DUF5400 PF17379.2 CEG44701.1 - 0.15 12.5 0.1 0.45 11.0 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5400) Baculo_IE-1 PF05290.11 CEG44702.1 - 0.0042 17.0 0.1 0.0042 17.0 0.1 1.1 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Propep_M14 PF02244.16 CEG44704.1 - 0.014 15.8 2.3 0.06 13.7 1.1 2.0 2 0 0 2 2 2 0 Carboxypeptidase activation peptide SecA_PP_bind PF01043.20 CEG44706.1 - 0.021 15.5 0.1 0.031 14.9 0.1 1.2 1 0 0 1 1 1 0 SecA preprotein cross-linking domain SH3_13 PF18335.1 CEG44707.1 - 0.097 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Bacillus_HBL PF05791.11 CEG44709.1 - 0.033 14.0 0.6 0.061 13.1 0.6 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) IML1 PF12257.8 CEG44709.1 - 0.074 12.2 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 Imm30 PF15565.6 CEG44710.1 - 0.053 13.6 0.7 0.16 12.1 0.7 1.8 1 0 0 1 1 1 0 Immunity protein 30 HTH_57 PF18679.1 CEG44710.1 - 0.068 13.5 0.9 0.19 12.1 0.4 1.9 2 0 0 2 2 2 0 ThcOx helix turn helix domain RsbRD_N PF14361.6 CEG44710.1 - 0.16 12.7 2.2 0.25 12.1 0.4 2.2 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Pkinase PF00069.25 CEG44714.1 - 1.3e-51 175.5 0.0 3.8e-50 170.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain IlvC PF01450.19 CEG44714.1 - 6.5e-43 146.5 0.1 4.5e-33 114.5 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 CEG44714.1 - 6.3e-36 123.4 0.2 1.1e-35 122.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase_Tyr PF07714.17 CEG44714.1 - 2e-31 109.2 0.0 9.3e-30 103.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEG44714.1 - 2.7e-05 23.6 0.1 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG44714.1 - 0.0047 16.9 0.1 3 7.7 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG44714.1 - 0.0061 15.4 0.2 0.036 12.9 0.0 1.9 1 1 0 2 2 2 1 Fungal protein kinase DNA_pol_A_exo1 PF01612.20 CEG44715.1 - 1.3e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Glyco_hydro_3 PF00933.21 CEG44721.1 - 9.6e-47 159.9 0.0 1.4e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEG44721.1 - 5.3e-38 131.0 0.0 9.4e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CEG44721.1 - 2.1e-14 53.3 0.1 6e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DMRL_synthase PF00885.19 CEG44723.1 - 8.5e-13 48.3 0.3 1.1e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase AAA_12 PF13087.6 CEG44725.1 - 2.2e-60 203.7 0.2 7.2e-60 202.0 0.2 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG44725.1 - 4.7e-57 193.7 18.3 5e-33 115.0 0.4 4.8 3 2 2 5 5 5 2 AAA domain AAA_30 PF13604.6 CEG44725.1 - 1e-08 35.1 0.1 1.2e-07 31.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG44725.1 - 1.6e-05 25.3 0.1 0.00022 21.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain WH2 PF02205.20 CEG44725.1 - 0.11 12.3 0.5 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 WH2 motif Ran_BP1 PF00638.18 CEG44726.1 - 6.3e-37 126.6 1.3 9.6e-37 126.0 1.3 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CEG44726.1 - 0.00028 20.8 1.0 0.00073 19.5 1.0 1.7 1 1 0 1 1 1 1 WH1 domain DUF5486 PF17588.2 CEG44726.1 - 0.025 14.5 0.3 0.075 12.9 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5486) SLC35F PF06027.12 CEG44727.1 - 1.9e-74 250.9 19.2 2.2e-74 250.7 19.2 1.0 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 CEG44727.1 - 3.4e-14 52.8 14.1 7.5e-14 51.6 14.1 1.5 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CEG44727.1 - 2.3e-11 43.2 3.6 2.3e-11 43.2 3.6 2.0 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CEG44727.1 - 2.3e-11 44.0 19.4 6.6e-07 29.6 7.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 CEG44727.1 - 1.6e-05 24.2 3.3 1.6e-05 24.2 3.3 2.2 1 1 1 2 2 2 1 Magnesium transporter NIPA DUF2109 PF09882.9 CEG44727.1 - 0.035 14.1 3.6 0.23 11.5 0.2 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Homeobox_KN PF05920.11 CEG44728.1 - 1.1e-18 66.9 0.1 3.7e-18 65.1 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEG44728.1 - 1.1e-08 34.8 0.2 3.5e-08 33.2 0.2 1.9 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CEG44728.1 - 0.0035 16.8 0.0 3.1 7.3 0.0 2.7 1 1 1 2 2 2 2 Homeodomain leucine-zipper encoding, Homez DUF3275 PF11679.8 CEG44728.1 - 0.036 14.0 1.4 0.075 13.0 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ubiquitin PF00240.23 CEG44734.1 - 3.1e-09 36.5 0.0 6.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG44734.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 CEG44734.1 - 0.001 19.7 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF3598 PF12204.8 CEG44734.1 - 0.031 13.8 0.2 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3598) FeS_assembly_P PF01883.19 CEG44734.1 - 0.064 13.4 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Rad60-SLD_2 PF13881.6 CEG44734.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PDZ_6 PF17820.1 CEG44735.1 - 9.9e-09 34.9 0.1 0.00085 19.1 0.0 3.2 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 CEG44735.1 - 4.2e-06 27.0 0.4 0.003 17.9 0.0 3.0 3 0 0 3 3 3 2 PDZ domain HK_sensor PF16750.5 CEG44738.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase Chromo PF00385.24 CEG44739.1 - 1.2e-11 44.3 0.5 1.9e-11 43.7 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TB2_DP1_HVA22 PF03134.19 CEG44740.1 - 3.1e-13 49.4 16.3 3.4e-09 36.5 1.6 3.7 3 0 0 3 3 3 3 TB2/DP1, HVA22 family MHCassoc_trimer PF08831.10 CEG44740.1 - 0.066 13.2 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain PIP5K PF01504.18 CEG44742.1 - 2.8e-71 240.0 0.0 5.7e-70 235.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 CEG44742.1 - 4.5e-06 25.9 17.8 1e-05 24.7 17.8 1.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 CEG44742.1 - 0.00014 21.2 19.1 0.00022 20.6 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TPR_1 PF00515.28 CEG44744.1 - 1.4e-10 40.5 10.6 0.0045 16.7 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44744.1 - 5.9e-10 38.5 15.8 3.3e-05 23.7 0.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44744.1 - 1.3e-05 24.8 8.4 0.0044 16.7 1.3 3.6 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 CEG44744.1 - 0.00041 20.6 6.1 0.0054 17.0 5.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Bap31_Bap29_C PF18035.1 CEG44744.1 - 0.00044 20.2 1.3 0.00044 20.2 1.3 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0242 PF06785.11 CEG44744.1 - 0.021 15.0 1.1 0.032 14.3 1.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_8 PF13181.6 CEG44744.1 - 0.025 14.8 13.3 0.14 12.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44744.1 - 0.03 15.0 9.3 1.6 9.5 5.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44744.1 - 0.31 11.5 7.6 2.9 8.5 0.1 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG44744.1 - 4.7 8.3 10.9 16 6.6 0.6 4.1 1 1 3 4 4 4 0 Tetratricopeptide repeat Tetraspanin PF00335.20 CEG44746.1 - 8.8e-15 55.0 19.0 1.5e-14 54.2 19.0 1.5 1 1 0 1 1 1 1 Tetraspanin family Trp_oprn_chp PF09534.10 CEG44746.1 - 0.0059 16.4 3.0 0.25 11.1 0.4 2.4 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FA_desaturase PF00487.24 CEG44746.1 - 0.33 10.8 6.9 1.6 8.5 2.7 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Wzy_C_2 PF11846.8 CEG44746.1 - 0.44 10.4 4.4 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3043 PF11241.8 CEG44746.1 - 1.4 9.0 3.6 14 5.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF2207 PF09972.9 CEG44746.1 - 1.6 7.4 8.1 11 4.7 5.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Oxidored_q2 PF00420.24 CEG44746.1 - 1.7 8.3 14.4 0.14 11.8 4.6 3.1 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Wzy_C PF04932.15 CEG44746.1 - 2.6 7.7 7.2 0.7 9.5 1.4 2.3 3 0 0 3 3 3 0 O-Antigen ligase PI3_PI4_kinase PF00454.27 CEG44747.1 - 1e-73 248.3 0.0 2.3e-73 247.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CEG44747.1 - 4.8e-60 203.6 1.3 1.3e-58 198.9 1.3 2.7 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 CEG44747.1 - 4.2e-43 147.0 0.0 5.3e-34 117.5 0.0 5.9 4 2 1 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CEG44747.1 - 1.5e-33 115.1 2.4 1.5e-33 115.1 2.4 4.1 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain NOC3p PF07540.11 CEG44747.1 - 3.7e-26 91.4 1.8 3.1e-25 88.4 1.8 2.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 CEG44747.1 - 2.6e-23 82.9 0.2 1.1e-22 80.9 0.2 2.2 1 0 0 1 1 1 1 CBF/Mak21 family FATC PF02260.20 CEG44747.1 - 5.8e-15 54.8 0.1 1.8e-14 53.2 0.1 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CEG44747.1 - 1e-10 40.9 6.4 5.4 7.6 0.0 11.2 10 0 0 10 10 10 1 HEAT repeat TPR_19 PF14559.6 CEG44747.1 - 1.4e-08 35.1 0.2 0.077 13.5 0.0 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat HEAT_2 PF13646.6 CEG44747.1 - 4e-07 30.3 8.3 0.32 11.4 0.3 8.7 9 0 0 9 9 9 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CEG44747.1 - 0.0026 18.3 0.4 9.4 6.9 0.1 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CEG44747.1 - 0.006 16.7 0.3 0.64 10.2 0.0 4.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CEG44747.1 - 0.0097 16.4 11.3 15 6.2 0.0 8.8 10 1 1 11 11 8 0 HEAT-like repeat N1221 PF07923.13 CEG44747.1 - 0.012 14.8 0.2 0.54 9.4 0.1 2.6 2 0 0 2 2 2 0 N1221-like protein TPR_14 PF13428.6 CEG44747.1 - 0.086 13.7 4.5 29 5.8 0.0 5.3 4 1 1 5 5 3 0 Tetratricopeptide repeat DUF2847 PF11009.8 CEG44747.1 - 0.097 12.6 0.1 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Tti2 PF10521.9 CEG44747.1 - 0.1 12.1 7.5 6.4 6.2 0.2 4.6 5 1 1 6 6 6 0 Tti2 family DTW PF03942.15 CEG44748.1 - 2.6e-16 59.9 0.0 4.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 DTW domain zf-CCHC PF00098.23 CEG44748.1 - 2.6e-08 33.6 18.1 0.00036 20.5 4.2 2.6 1 1 1 2 2 2 2 Zinc knuckle U1snRNP70_N PF12220.8 CEG44748.1 - 0.039 14.6 0.5 0.084 13.5 0.5 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NAD_binding_1 PF00175.21 CEG44749.1 - 6.4e-29 100.8 0.0 1.2e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEG44749.1 - 5.5e-21 74.8 0.0 9.5e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEG44749.1 - 2.2e-06 27.9 0.1 0.00041 20.5 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain ERCC4 PF02732.15 CEG44750.1 - 4e-20 72.6 0.0 9.3e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain PAP2 PF01569.21 CEG44751.1 - 5.4e-25 87.7 0.8 9.8e-25 86.9 0.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CEG44751.1 - 6.3e-05 22.7 1.0 0.14 11.8 0.6 2.3 2 0 0 2 2 2 2 PAP2 superfamily AAA_6 PF12774.7 CEG44752.1 - 0.064 12.2 0.1 0.069 12.1 0.1 1.0 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Kinesin PF00225.23 CEG44753.1 - 8.5e-09 34.8 0.1 8.5e-09 34.8 0.1 2.7 2 0 0 2 2 2 1 Kinesin motor domain HTH_54 PF18607.1 CEG44753.1 - 3.2 7.9 7.4 4.3 7.5 0.3 3.0 2 0 0 2 2 2 0 ParA helix turn helix domain Bmt2 PF11968.8 CEG44754.1 - 0.0089 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 TRAUB PF08164.12 CEG44759.1 - 1.9e-23 82.7 1.0 7e-23 81.0 0.1 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CEG44759.1 - 3.1e-14 53.9 1.4 3.1e-14 53.9 1.4 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor CCDC53 PF10152.9 CEG44760.1 - 3.6e-22 79.4 17.0 3e-12 47.2 0.2 4.5 5 0 0 5 5 5 2 Subunit CCDC53 of WASH complex LAP1C PF05609.12 CEG44760.1 - 0.043 12.9 0.1 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3295 PF11702.8 CEG44760.1 - 0.063 12.6 2.9 0.028 13.8 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Tankyrase_bdg_C PF15327.6 CEG44760.1 - 0.16 12.4 1.3 1.8 9.0 0.6 2.2 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain Ribosomal_L13e PF01294.18 CEG44761.1 - 1.4e-74 249.9 3.5 1.6e-74 249.6 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e SAC3_GANP PF03399.16 CEG44762.1 - 1e-86 291.0 1.4 1e-86 291.0 1.4 1.9 2 0 0 2 2 2 1 SAC3/GANP family Coprogen_oxidas PF01218.18 CEG44765.1 - 3.2e-134 446.3 0.0 3.8e-134 446.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase GFO_IDH_MocA PF01408.22 CEG44766.1 - 6.3e-10 39.9 0.0 1.1e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEG44766.1 - 6.6e-06 26.1 0.0 1.8e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.24 CEG44766.1 - 0.0037 17.6 0.0 0.31 11.4 0.0 2.9 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_M17 PF00883.21 CEG44768.1 - 3.3e-90 302.5 1.8 4.4e-87 292.3 0.1 3.0 2 1 1 3 3 3 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CEG44768.1 - 3.7e-11 43.0 0.0 7.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain WD40 PF00400.32 CEG44769.1 - 1.7e-33 114.1 21.3 1.3e-05 25.8 0.5 10.9 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG44769.1 - 1.3e-13 51.1 0.5 0.025 14.8 0.1 7.1 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG44769.1 - 0.00028 20.3 0.0 2.9 7.1 0.1 3.7 2 2 0 3 3 3 3 WD40-like domain Nucleoporin_N PF08801.11 CEG44769.1 - 0.023 13.4 0.7 5.9 5.5 0.1 3.0 3 0 0 3 3 3 0 Nup133 N terminal like IKI3 PF04762.12 CEG44769.1 - 0.14 10.1 0.1 1.5 6.7 0.0 2.2 2 0 0 2 2 2 0 IKI3 family SH3_2 PF07653.17 CEG44770.1 - 4.5e-08 32.7 0.0 1.4e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEG44770.1 - 9.9e-07 28.5 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEG44770.1 - 0.00057 19.4 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain hSH3 PF14603.6 CEG44770.1 - 0.013 15.9 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF572 PF04502.13 CEG44770.1 - 0.56 9.8 32.3 0.85 9.2 32.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4407 PF14362.6 CEG44770.1 - 8.3 5.7 21.9 3.6 6.9 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CLP1_P PF16575.5 CEG44771.1 - 8e-42 143.2 0.0 1.2e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 CEG44771.1 - 0.021 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CEG44771.1 - 0.046 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEG44771.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEG44771.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.18 CEG44772.1 - 1e-85 282.2 17.3 4.1e-15 56.1 0.0 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG44772.1 - 5.4e-56 185.4 28.8 7e-10 38.4 0.1 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 CEG44772.1 - 0.0066 16.4 4.2 2.5 8.2 0.0 4.1 5 0 0 5 5 5 1 Kelch motif Hira PF07569.11 CEG44772.1 - 0.0067 16.2 0.0 52 3.4 0.0 4.6 5 1 0 5 5 5 0 TUP1-like enhancer of split LUD_dom PF02589.15 CEG44772.1 - 0.014 15.1 0.0 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 LUD domain SIS_2 PF13580.6 CEG44772.1 - 0.016 15.3 0.3 12 5.9 0.0 3.5 4 0 0 4 4 4 0 SIS domain DUF4213 PF13938.6 CEG44772.1 - 1.5 9.1 5.8 17 5.7 0.1 3.8 3 2 0 3 3 3 0 Putative heavy-metal chelation DUF5001 PF16392.5 CEG44775.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Ig-like domain DUF4825 PF16107.5 CEG44775.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) Ank_4 PF13637.6 CEG44777.1 - 1.3e-21 76.7 25.1 3.6e-07 30.6 0.1 9.1 8 3 0 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG44777.1 - 5.3e-21 75.0 14.0 8.2e-07 29.5 0.2 6.3 3 1 5 8 8 8 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG44777.1 - 2.4e-19 69.1 17.8 0.024 15.0 0.1 10.2 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG44777.1 - 4.7e-13 48.0 10.3 2.1 9.2 0.0 9.5 11 0 0 11 11 11 4 Ankyrin repeat DUF5049 PF16468.5 CEG44777.1 - 0.00036 20.3 0.4 0.047 13.6 0.1 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF5049) DUF2575 PF10837.8 CEG44777.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) DUF3447 PF11929.8 CEG44777.1 - 0.053 13.5 2.8 2.2 8.3 0.0 4.3 3 2 0 4 4 4 0 Domain of unknown function (DUF3447) Ank PF00023.30 CEG44777.1 - 0.12 12.8 1.6 1.5e+02 3.1 0.0 5.5 5 3 1 6 6 6 0 Ankyrin repeat RNA_GG_bind PF10258.9 CEG44778.1 - 2.2e-16 59.6 0.1 3.6e-15 55.8 0.1 2.3 1 1 0 1 1 1 1 PHAX RNA-binding domain DUF5644 PF18712.1 CEG44780.1 - 0.01 15.9 0.8 0.044 13.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5644) RasGEF_N_2 PF14663.6 CEG44780.1 - 0.16 12.4 1.5 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain bZIP_2 PF07716.15 CEG44783.1 - 0.012 15.7 3.6 0.034 14.2 3.6 1.7 1 0 0 1 1 1 0 Basic region leucine zipper BBP1_C PF15272.6 CEG44783.1 - 0.37 10.6 5.3 0.73 9.6 5.3 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Condensin2nSMC PF12422.8 CEG44784.1 - 0.011 16.0 2.1 0.035 14.3 0.1 2.7 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit DUF1640 PF07798.11 CEG44785.1 - 0.051 13.6 3.1 0.14 12.2 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YqzH PF14164.6 CEG44785.1 - 0.14 12.3 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 YqzH-like protein Myc-LZ PF02344.15 CEG44785.1 - 1.9 8.7 8.9 0.57 10.3 4.3 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain KRTDAP PF15200.6 CEG44787.1 - 0.035 13.9 0.3 0.086 12.6 0.3 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Ribosomal_L19e PF01280.20 CEG44790.1 - 1.1e-63 213.6 12.0 1.1e-63 213.6 12.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e Med9 PF07544.13 CEG44791.1 - 1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF473 PF04322.12 CEG44791.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF473) Caps_synth_GfcC PF06251.11 CEG44791.1 - 0.043 13.4 0.4 0.055 13.1 0.4 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Fez1 PF06818.15 CEG44791.1 - 0.079 13.4 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Fez1 Mito_carr PF00153.27 CEG44792.1 - 5.9e-63 208.8 0.4 1.7e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3873 PF12989.7 CEG44793.1 - 0.31 11.4 1.2 24 5.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Thioredoxin_8 PF13905.6 CEG44800.1 - 1.1e-23 83.4 0.0 1.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CEG44800.1 - 3.8e-07 29.9 0.0 9.8e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 CEG44800.1 - 9.1e-07 28.8 0.0 0.012 15.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 CEG44800.1 - 1.5e-06 28.1 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CEG44800.1 - 2.1e-06 28.1 0.0 4.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CEG44800.1 - 0.031 13.6 0.0 0.29 10.5 0.0 2.0 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 CEG44800.1 - 0.064 13.5 0.9 0.19 11.9 0.0 2.2 2 1 0 2 2 2 0 Glutaredoxin Myosin_head PF00063.21 CEG44801.1 - 1.1e-227 757.6 0.8 1.3e-227 757.3 0.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEG44801.1 - 2.7e-14 51.6 19.9 1.9e-05 24.1 0.1 4.9 4 0 0 4 4 4 4 IQ calmodulin-binding motif PDZ_6 PF17820.1 CEG44801.1 - 2.1e-05 24.3 0.0 0.37 10.7 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 CEG44801.1 - 0.00072 19.9 0.1 0.024 15.0 0.1 3.0 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 CEG44801.1 - 0.0023 18.2 0.3 0.89 9.9 0.1 3.0 3 0 0 3 3 3 1 PDZ domain RNA_helicase PF00910.22 CEG44801.1 - 0.0084 16.5 0.1 0.82 10.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.26 CEG44801.1 - 0.021 14.5 0.1 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-MYND PF01753.18 CEG44802.1 - 7.1e-07 29.2 11.4 7.1e-07 29.2 11.4 1.5 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CEG44802.1 - 0.058 13.5 6.9 0.24 11.5 6.9 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Jacalin PF01419.17 CEG44804.1 - 2e-09 37.4 0.0 4.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Myosin_head PF00063.21 CEG44805.1 - 3.2e-179 597.4 0.0 6.9e-125 417.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 CEG44805.1 - 2.3e-05 23.8 8.9 0.073 12.9 4.9 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 CEG44805.1 - 0.0038 17.5 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG44805.1 - 0.04 14.3 0.1 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CEG44805.1 - 0.052 13.0 0.1 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TPR_2 PF07719.17 CEG44806.1 - 2.2e-07 30.4 0.3 2.6e-06 27.1 0.5 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44806.1 - 2.5e-07 30.2 0.3 1.7e-05 24.4 0.0 2.8 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.28 CEG44806.1 - 5e-07 29.3 0.5 1.5e-06 27.7 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44806.1 - 6.8e-06 26.5 0.1 9.2e-05 22.9 0.0 2.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44806.1 - 6.1e-05 22.9 0.3 0.00093 19.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44806.1 - 7.1e-05 23.0 0.1 0.00018 21.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat YccV-like PF08755.11 CEG44806.1 - 0.00017 22.0 0.0 0.0028 18.1 0.0 2.5 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like TPR_14 PF13428.6 CEG44806.1 - 0.00027 21.5 0.0 0.11 13.4 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44806.1 - 0.0007 20.2 0.1 0.0025 18.4 0.0 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44806.1 - 0.0032 17.7 0.1 0.061 13.7 0.0 2.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG44806.1 - 0.0079 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG44806.1 - 0.023 14.6 0.1 0.55 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG44806.1 - 0.054 14.2 0.0 27 5.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG44806.1 - 0.15 12.1 0.4 16 5.7 0.1 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 CEG44807.1 - 3.1e-48 163.8 1.3 5.1e-48 163.1 1.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CEG44807.1 - 9.8e-17 61.4 1.0 5.2e-16 59.1 0.0 2.6 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CEG44807.1 - 0.0011 18.9 0.2 0.015 15.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44807.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_meth_N PF18284.1 CEG44808.1 - 1 9.3 4.8 1.5 8.8 1.1 2.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain BET PF17035.5 CEG44808.1 - 5.1 7.4 7.0 1.4 9.1 0.0 3.6 5 0 0 5 5 5 0 Bromodomain extra-terminal - transcription regulation BCDHK_Adom3 PF10436.9 CEG44809.1 - 4.7e-55 185.8 0.0 6.3e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEG44809.1 - 1.1e-13 51.6 0.0 4.6e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEG44809.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAM47 PF14642.6 CEG44811.1 - 0.097 12.2 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 FAM47 family DUF4357 PF14267.6 CEG44811.1 - 0.14 12.2 1.1 0.32 11.0 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) FANCL_C PF11793.8 CEG44816.1 - 0.15 12.3 0.4 0.75 10.0 0.1 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain Ras PF00071.22 CEG44817.1 - 9.6e-23 80.6 0.0 1.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG44817.1 - 2.3e-14 53.7 0.0 6.5e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH2 PF00017.24 CEG44817.1 - 2.4e-08 33.9 0.0 5.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Arf PF00025.21 CEG44817.1 - 6.6e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG44817.1 - 0.0029 17.0 0.1 0.0081 15.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG44817.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CEG44817.1 - 0.066 13.5 1.2 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Med28 PF11594.8 CEG44817.1 - 0.067 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Mediator complex subunit 28 Aa_trans PF01490.18 CEG44818.1 - 1.9e-67 227.8 3.6 3e-67 227.1 3.6 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein EMP70 PF02990.16 CEG44819.1 - 1.7e-151 505.4 15.6 2.8e-151 504.7 15.6 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Aminotran_5 PF00266.19 CEG44821.1 - 6.7e-17 61.5 0.0 9.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V LRRNT PF01462.18 CEG44824.1 - 3.5e-06 26.5 0.8 6.5e-06 25.7 0.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 CEG44824.1 - 1.9e-05 24.3 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat ST7 PF04184.12 CEG44825.1 - 0.047 12.2 3.9 0.062 11.8 3.9 1.1 1 0 0 1 1 1 0 ST7 protein Methyltransf_16 PF10294.9 CEG44827.1 - 1.2e-28 100.0 0.1 9.6e-27 93.8 0.1 2.3 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CEG44827.1 - 0.00064 19.6 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG44827.1 - 0.00081 19.0 0.3 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 CEG44827.1 - 0.0012 18.6 0.1 0.0021 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 CEG44827.1 - 0.0013 19.5 0.0 0.0034 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG44827.1 - 0.0024 18.6 0.3 0.0054 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 CEG44827.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.15 CEG44827.1 - 0.052 12.9 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 CEG44827.1 - 0.094 12.5 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CEG44827.1 - 0.12 12.4 0.9 0.29 11.1 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain TPR_1 PF00515.28 CEG44828.1 - 1.8e-13 49.7 7.3 4.5e-05 23.1 1.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44828.1 - 2.8e-13 49.9 8.1 7.8e-09 35.7 2.7 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG44828.1 - 3.5e-12 45.4 5.8 0.0001 22.1 0.6 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEG44828.1 - 6.9e-10 38.5 6.9 2.6e-06 27.1 0.5 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44828.1 - 5e-06 26.2 7.8 0.0016 18.3 0.4 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44828.1 - 8.1e-06 25.7 4.3 0.0029 17.7 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG44828.1 - 0.00053 19.5 4.1 0.00059 19.3 1.5 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 CEG44828.1 - 0.0012 18.1 0.9 0.13 11.4 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG44828.1 - 0.0044 17.7 2.0 7.6 7.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44828.1 - 0.0046 16.6 0.1 0.72 9.6 0.0 2.9 2 1 0 2 2 2 1 TPR repeat DUF5113 PF17140.4 CEG44828.1 - 0.0075 16.1 0.3 7.9 6.3 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5113) PPR PF01535.20 CEG44828.1 - 0.043 14.1 0.8 2.8 8.4 0.0 3.4 4 0 0 4 4 4 0 PPR repeat TPR_16 PF13432.6 CEG44828.1 - 0.19 12.4 0.4 1.9 9.2 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44828.1 - 0.19 12.2 3.5 4.9 7.7 0.5 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG44828.1 - 0.2 11.9 1.7 9.5 6.4 0.1 3.0 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44828.1 - 0.53 10.8 0.1 0.53 10.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 CEG44828.1 - 0.69 9.3 5.1 0.36 10.3 1.5 2.0 2 1 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Mon1 PF03164.14 CEG44829.1 - 4.3e-59 200.6 0.8 5.8e-59 200.2 0.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Gluconate_2-dh3 PF13618.6 CEG44829.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DDE_1 PF03184.19 CEG44831.1 - 0.00036 20.2 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RXLR PF16810.5 CEG44832.1 - 0.0075 16.7 0.0 0.0081 16.6 0.0 1.0 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Paz_1 PF18349.1 CEG44832.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 PAZ domain Acyl-CoA_dh_1 PF00441.24 CEG44834.1 - 1.5e-43 148.6 2.0 1.4e-42 145.5 0.3 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEG44834.1 - 3.8e-26 91.1 0.0 7.5e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEG44834.1 - 2.6e-24 86.1 0.0 5.8e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEG44834.1 - 1.4e-10 41.6 0.0 1.4e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3336 PF11815.8 CEG44835.1 - 9.2e-30 103.2 0.1 1.7e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEG44835.1 - 5.2e-24 85.6 0.2 1.5e-23 84.1 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase TraH PF06122.11 CEG44835.1 - 0.07 12.4 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein GBP PF02263.19 CEG44836.1 - 5.2e-53 180.0 0.0 1.9e-52 178.1 0.0 2.0 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CEG44836.1 - 7.5e-15 55.1 31.0 9e-10 38.4 0.2 4.6 2 1 3 5 5 5 2 Guanylate-binding protein, C-terminal domain Radial_spoke PF04712.12 CEG44837.1 - 2.9e-08 33.1 0.5 8.6e-05 21.7 0.1 2.6 2 1 1 3 3 3 2 Radial spokehead-like protein DEAD PF00270.29 CEG44838.1 - 1.5e-19 70.5 0.0 2.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEG44838.1 - 9.5e-13 48.5 0.0 2.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 CEG44838.1 - 4.8e-11 42.7 1.0 5.1e-07 29.7 0.1 2.8 1 1 1 2 2 2 2 Dicer dimerisation domain Helicase_C PF00271.31 CEG44838.1 - 6.4e-10 39.4 0.0 2e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.17 CEG44838.1 - 3.2e-05 23.8 0.0 8.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CEG44838.1 - 0.00087 19.6 0.1 0.0056 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEG44838.1 - 0.029 14.1 0.0 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CEG44838.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 CEG44838.1 - 0.036 14.4 0.0 0.74 10.2 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 CEG44838.1 - 0.038 13.5 0.0 0.099 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CEG44838.1 - 0.05 14.1 0.0 0.19 12.2 0.0 2.2 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CEG44838.1 - 0.071 12.3 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CEG44838.1 - 0.12 12.7 0.2 2.1 8.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEG44838.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Retrotran_gag_2 PF14223.6 CEG44839.1 - 4.5e-12 45.8 5.7 1.4e-11 44.3 5.7 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 CEG44840.1 - 1.8e-12 47.4 0.0 4.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) BAF PF02961.14 CEG44843.1 - 0.0041 17.5 0.0 0.016 15.6 0.0 2.0 1 1 0 2 2 2 1 Barrier to autointegration factor IMS_HHH PF11798.8 CEG44843.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif HHH_5 PF14520.6 CEG44843.1 - 0.12 13.0 0.1 0.3 11.7 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HSF_DNA-bind PF00447.17 CEG44844.1 - 3.9e-21 75.5 1.6 7.9e-21 74.5 1.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Cation_ATPase PF13246.6 CEG44844.1 - 0.028 14.5 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) GTP_EFTU PF00009.27 CEG44845.1 - 3.4e-37 127.9 0.0 3.4e-37 127.9 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEG44845.1 - 6.6e-19 68.0 0.0 2.4e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 CEG44845.1 - 4.2e-17 61.8 0.9 8.7e-17 60.8 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CEG44845.1 - 4.3e-10 39.9 9.1 7.2e-07 29.5 0.5 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG44845.1 - 2.4e-07 30.8 0.3 2e-06 27.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CEG44845.1 - 5.5e-05 23.1 0.0 0.00023 21.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CEG44845.1 - 0.015 15.6 0.1 0.099 12.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain PX PF00787.24 CEG44846.1 - 0.00011 22.2 0.3 0.00018 21.4 0.3 1.4 1 0 0 1 1 1 1 PX domain Peptidase_C1 PF00112.23 CEG44848.1 - 2.3e-45 155.3 0.9 3.3e-45 154.8 0.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF4863 PF16155.5 CEG44848.1 - 0.0091 15.9 0.1 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4863) Peptidase_C1_2 PF03051.15 CEG44848.1 - 0.018 13.8 0.3 0.03 13.1 0.3 1.3 1 0 0 1 1 1 0 Peptidase C1-like family YscO PF07321.12 CEG44849.1 - 6.3e-06 26.2 14.8 0.0023 17.9 5.2 2.3 2 0 0 2 2 2 2 Type III secretion protein YscO IFT57 PF10498.9 CEG44849.1 - 0.0016 17.5 7.8 0.015 14.3 3.0 2.1 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Snapin_Pallidin PF14712.6 CEG44849.1 - 0.014 15.7 8.7 0.11 13.0 0.2 2.8 2 1 0 2 2 2 0 Snapin/Pallidin Sec34 PF04136.15 CEG44849.1 - 0.015 15.2 8.6 0.34 10.8 1.3 2.2 2 0 0 2 2 2 0 Sec34-like family DUF713 PF05218.14 CEG44849.1 - 0.021 14.6 4.7 0.21 11.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF713) CENP-Q PF13094.6 CEG44849.1 - 0.024 14.8 15.8 0.066 13.4 10.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Josephin PF02099.17 CEG44849.1 - 0.035 14.2 1.2 0.047 13.8 0.7 1.6 1 1 0 1 1 1 0 Josephin RasGAP_C PF03836.15 CEG44849.1 - 0.039 14.1 8.2 0.042 14.0 1.9 2.4 2 1 0 2 2 2 0 RasGAP C-terminus BAR_3 PF16746.5 CEG44849.1 - 0.059 13.1 8.9 0.19 11.4 2.3 2.1 2 0 0 2 2 2 0 BAR domain of APPL family ApoO PF09769.9 CEG44849.1 - 0.09 12.7 3.6 4.3 7.3 0.3 2.4 2 1 0 2 2 2 0 Apolipoprotein O DUF1664 PF07889.12 CEG44849.1 - 0.1 12.7 10.3 0.2 11.7 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CEG44849.1 - 0.1 13.1 18.3 0.23 12.0 3.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 CEG44849.1 - 0.11 12.8 7.6 1.3 9.3 0.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 CEG44849.1 - 0.11 12.5 10.4 0.59 10.1 3.0 2.2 2 0 0 2 2 2 0 Laminin Domain II FmiP_Thoc5 PF09766.9 CEG44849.1 - 0.11 11.7 6.4 1.4 8.1 4.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 FlaC_arch PF05377.11 CEG44849.1 - 0.16 12.4 4.9 0.51 10.8 0.2 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 CEG44849.1 - 0.19 11.8 11.4 0.64 10.1 1.0 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.17 CEG44849.1 - 0.23 11.4 9.5 0.57 10.1 0.6 2.8 2 1 0 2 2 2 0 Prefoldin subunit ERM PF00769.19 CEG44849.1 - 0.27 11.0 22.2 0.13 12.1 7.1 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rootletin PF15035.6 CEG44849.1 - 0.31 11.0 15.9 1.7 8.6 15.9 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 CEG44849.1 - 0.53 11.0 11.6 0.78 10.4 1.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CC2-LZ PF16516.5 CEG44849.1 - 0.55 10.6 15.3 1.1 9.7 3.1 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4763 PF15960.5 CEG44849.1 - 0.59 9.4 13.6 5.3 6.3 13.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1492 PF07374.11 CEG44849.1 - 0.65 10.2 4.9 1.6 8.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Cnn_1N PF07989.11 CEG44849.1 - 0.68 10.1 11.1 0.3 11.3 2.5 2.9 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 SKA2 PF16740.5 CEG44849.1 - 0.79 9.5 13.0 2.3 8.0 6.3 2.6 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Csm1_N PF18504.1 CEG44849.1 - 1 9.7 10.8 0.45 10.9 0.5 3.2 1 1 3 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 CEG44849.1 - 1.2 7.9 19.1 1.7 7.5 4.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.12 CEG44849.1 - 2.2 6.3 15.0 4.8 5.2 15.0 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DHR10 PF18595.1 CEG44849.1 - 2.3 8.3 21.8 0.2 11.7 6.3 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF2514 PF10721.9 CEG44849.1 - 2.3 8.2 11.5 0.56 10.2 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) NPV_P10 PF05531.12 CEG44849.1 - 2.4 8.7 9.1 1.5 9.4 0.8 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prp19 PF08606.11 CEG44849.1 - 2.5 8.1 9.2 0.77 9.8 2.8 3.0 2 2 1 3 3 3 0 Prp19/Pso4-like Mod_r PF07200.13 CEG44849.1 - 3.1 7.9 13.1 3 7.9 2.5 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CorA PF01544.18 CEG44849.1 - 3.7 6.8 12.5 1.9 7.7 4.6 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein LXG PF04740.12 CEG44849.1 - 3.9 7.1 11.3 0.88 9.2 0.3 2.5 2 1 0 2 2 2 0 LXG domain of WXG superfamily Fib_alpha PF08702.10 CEG44849.1 - 4.4 7.5 11.9 4.7 7.4 3.2 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family kleA_kleC PF17383.2 CEG44849.1 - 4.5 7.7 9.1 0.5 10.7 2.3 2.6 2 2 0 2 2 2 0 Uncharacterized KorC regulated protein A Cluap1 PF10234.9 CEG44849.1 - 4.8 6.5 14.4 31 3.9 12.1 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 TMF_DNA_bd PF12329.8 CEG44849.1 - 5.6 7.0 12.6 1.7 8.7 2.4 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HAUS6_N PF14661.6 CEG44849.1 - 7.6 6.0 13.7 2.8 7.5 6.3 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Alba PF01918.21 CEG44850.1 - 1e-20 73.3 1.9 1.8e-20 72.5 1.9 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CEG44850.1 - 3.4e-05 23.8 10.5 0.00015 21.8 10.5 2.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P NusB PF01029.18 CEG44850.1 - 0.038 14.2 0.7 0.094 13.0 0.7 1.6 1 0 0 1 1 1 0 NusB family eIF-3c_N PF05470.12 CEG44851.1 - 2.2e-148 495.2 39.4 8.6e-145 483.4 39.4 3.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CEG44851.1 - 7.3e-11 42.5 0.0 2.7e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 PCI domain DUF4201 PF13870.6 CEG44851.1 - 0.36 10.6 12.4 0.037 13.8 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Zip PF02535.22 CEG44851.1 - 5 6.2 6.5 10 5.2 6.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SNARE PF05739.19 CEG44852.1 - 1.2e-05 25.2 0.4 2.8e-05 24.0 0.4 1.7 1 0 0 1 1 1 1 SNARE domain HTH_Tnp_IS630 PF01710.16 CEG44852.1 - 1 9.4 4.0 0.46 10.5 0.2 2.1 3 0 0 3 3 3 0 Transposase CENP-L PF13092.6 CEG44853.1 - 6.5e-08 32.9 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 HEAT PF02985.22 CEG44854.1 - 9.7e-06 25.4 4.9 0.27 11.6 0.0 5.5 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CEG44854.1 - 0.0036 17.6 2.4 29 5.1 0.0 4.3 3 0 0 3 3 3 3 HEAT repeats Ketoacyl-synt_2 PF13723.6 CEG44854.1 - 0.08 12.6 0.1 0.27 10.9 0.1 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain RRM_1 PF00076.22 CEG44855.1 - 1.1e-17 63.6 0.0 2.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-SNARE_C PF12352.8 CEG44855.1 - 1.4e-07 31.7 2.3 1.4e-07 31.7 2.3 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Herpes_UL69 PF05459.12 CEG44855.1 - 0.0069 15.7 0.4 0.021 14.2 0.4 1.8 1 1 0 1 1 1 1 Herpesvirus transcriptional regulator family RRM_5 PF13893.6 CEG44855.1 - 0.0078 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.19 CEG44855.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_occluded PF16842.5 CEG44855.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Occluded RNA-recognition motif CbiC PF02570.15 CEG44855.1 - 0.045 13.4 0.1 0.079 12.6 0.1 1.5 1 1 0 1 1 1 0 Precorrin-8X methylmutase BTB_2 PF02214.22 CEG44858.1 - 3.4e-11 43.3 0.1 7.2e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain eIF3g PF12353.8 CEG44859.1 - 1.1e-34 119.5 0.5 1.8e-34 118.9 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CEG44859.1 - 1.4e-19 69.6 0.0 2.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG44859.1 - 0.014 15.3 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CEG44859.1 - 0.017 15.4 0.8 6.5 7.0 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter AAA_33 PF13671.6 CEG44859.1 - 0.15 12.2 0.1 8.4 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 CEG44861.1 - 5.8e-08 32.9 8.4 5.8e-08 32.9 8.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG44861.1 - 1.7e-05 24.5 7.2 3.8e-05 23.4 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG44861.1 - 3e-05 24.2 7.8 9.1e-05 22.7 7.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG44861.1 - 3.4e-05 23.5 6.1 0.0001 22.0 6.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEG44861.1 - 0.00065 19.5 7.0 0.0015 18.4 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG44861.1 - 0.0035 17.3 6.0 0.0098 15.8 6.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3H2C3 PF17122.5 CEG44861.1 - 0.034 14.2 5.7 0.084 12.9 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 CEG44861.1 - 0.039 14.0 5.8 0.03 14.4 2.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG44861.1 - 0.077 12.9 5.5 0.28 11.1 5.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG44861.1 - 0.21 11.2 4.8 0.59 9.8 4.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF445 PF04286.12 CEG44862.1 - 3e-16 60.2 8.6 1.1e-09 38.6 0.0 4.1 2 2 2 4 4 4 4 Protein of unknown function (DUF445) RPN2_C PF18004.1 CEG44863.1 - 1.2e-37 129.3 7.7 1.9e-37 128.6 7.7 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CEG44863.1 - 1.1e-29 101.3 23.9 3.6e-07 30.3 0.0 8.8 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CEG44863.1 - 1e-19 70.7 3.9 1.6e-13 50.8 0.3 5.1 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 CEG44863.1 - 0.00026 21.0 3.3 0.56 10.6 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 CEG44863.1 - 0.00042 20.8 2.6 0.81 10.3 0.1 4.9 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 CEG44863.1 - 0.01 15.9 2.1 5.1 7.1 0.0 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ANAPC3 PF12895.7 CEG44863.1 - 0.019 15.2 0.2 0.21 11.8 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Utp13 PF08625.11 CEG44863.1 - 0.023 14.6 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Adaptin_N PF01602.20 CEG44863.1 - 0.62 8.5 3.8 30 3.0 0.2 4.0 4 1 0 4 4 4 0 Adaptin N terminal region TPR_19 PF14559.6 CEG44863.1 - 0.73 10.4 5.1 9.1 6.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.18 CEG44864.1 - 5.5e-31 107.7 25.1 6e-16 58.1 14.5 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Sec1 PF00995.23 CEG44865.1 - 1.5e-124 417.3 0.0 1.8e-124 417.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Fucose_iso_C PF02952.17 CEG44865.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain SSURE PF11966.8 CEG44868.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-binding repeat LRR_4 PF12799.7 CEG44869.1 - 7.3e-13 48.5 13.5 2.9e-06 27.5 0.1 3.2 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG44869.1 - 1.4e-10 41.0 5.2 1.5e-07 31.0 0.9 2.2 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 CEG44869.1 - 2.7e-07 30.3 10.6 0.00075 19.2 5.6 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CEG44869.1 - 0.00014 21.6 11.4 2.3 8.5 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 CEG44869.1 - 1.9 9.4 17.1 12 6.9 1.2 5.0 4 1 1 5 5 5 0 Leucine Rich Repeat zf-RING_2 PF13639.6 CEG44870.1 - 2.3e-12 47.0 14.2 2.3e-12 47.0 14.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CEG44870.1 - 1.1e-10 41.1 7.7 3.2e-10 39.6 7.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CEG44870.1 - 9.5e-06 25.8 12.4 2.2e-05 24.7 12.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG44870.1 - 2.2e-05 24.2 10.4 2.2e-05 24.2 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG44870.1 - 4.8e-05 23.1 15.5 5.7e-05 22.9 9.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG44870.1 - 8.2e-05 22.4 14.1 8.2e-05 22.4 14.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG44870.1 - 0.00016 21.6 7.6 0.00016 21.6 7.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG44870.1 - 0.00098 18.9 8.7 0.002 18.0 8.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CEG44870.1 - 0.0026 17.7 12.2 0.0026 17.7 12.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEG44870.1 - 0.034 14.2 7.4 0.1 12.7 7.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CEG44870.1 - 0.93 9.7 9.9 3.3 8.0 9.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.16 CEG44871.1 - 2.2e-18 66.3 28.2 2.2e-18 66.3 28.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily LRR_6 PF13516.6 CEG44874.1 - 0.002 18.0 5.3 1.6 9.0 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 CEG44874.1 - 0.01 16.3 9.5 1.4 9.5 0.3 5.0 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) DUF4606 PF15379.6 CEG44874.1 - 0.13 12.5 0.4 0.31 11.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) LRR_1 PF00560.33 CEG44874.1 - 2.3 9.1 5.7 20 6.2 0.5 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat FTSW_RODA_SPOVE PF01098.19 CEG44875.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.0 1 0 0 1 1 1 0 Cell cycle protein Ldh_1_N PF00056.23 CEG44880.1 - 3.2e-34 118.1 1.1 1e-33 116.4 0.3 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CEG44880.1 - 7.8e-18 65.0 0.5 1.2e-17 64.4 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain GATase_5 PF13507.6 CEG44880.1 - 0.01 15.0 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DDE_Tnp_1_3 PF13612.6 CEG44880.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DUF3707 PF12499.8 CEG44880.1 - 0.13 12.8 0.1 0.21 12.2 0.1 1.3 1 0 0 1 1 1 0 Pherophorin PIP5K PF01504.18 CEG44881.1 - 6.8e-75 251.8 0.1 1.3e-74 250.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 CEG44881.1 - 1.4e-07 31.2 8.7 3e-07 30.1 8.7 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.24 CEG44881.1 - 0.00052 19.4 2.5 0.00052 19.4 2.5 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) NPP1 PF05630.11 CEG44883.1 - 7e-51 173.1 0.0 8.3e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Tfb2 PF03849.14 CEG44886.1 - 1.3e-110 369.7 0.0 1.5e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CEG44886.1 - 1.2e-19 70.5 0.1 6e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CEG44886.1 - 0.0035 17.5 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Kelch_1 PF01344.25 CEG44887.1 - 1.9e-45 152.2 11.8 8.3e-09 34.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 CEG44887.1 - 3.3e-39 132.3 9.3 2.2e-06 27.5 0.3 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CEG44887.1 - 8.2e-39 130.7 14.6 9.7e-08 32.0 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEG44887.1 - 8.4e-39 131.2 19.6 7.2e-08 32.5 0.1 7.4 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_4 PF13418.6 CEG44887.1 - 7.8e-36 121.8 19.9 2e-07 30.9 0.3 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 CEG44887.1 - 1.2e-31 107.5 14.3 3.6e-07 29.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Tim17 PF02466.19 CEG44890.1 - 2.4e-05 24.7 13.2 0.00016 22.0 13.2 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 CEG44890.1 - 0.009 16.1 9.1 0.009 16.1 9.1 2.5 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide DUF3792 PF12670.7 CEG44890.1 - 3.3 7.9 9.8 1.3 9.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Gly-zipper_YMGG PF13441.6 CEG44890.1 - 7.5 6.4 32.5 1.1 9.0 23.4 2.8 2 2 0 2 2 2 0 YMGG-like Gly-zipper Ribosomal_L6 PF00347.23 CEG44891.1 - 1.4e-27 96.2 0.3 1.7e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4380 PF14315.6 CEG44891.1 - 0.035 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) ArfGap PF01412.18 CEG44892.1 - 2.5e-26 92.1 0.2 5.3e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 CEG44892.1 - 0.00016 21.8 1.5 0.00016 21.8 1.5 1.9 2 0 0 2 2 2 1 B-box zinc finger DHC_N1 PF08385.12 CEG44893.1 - 2e-156 521.9 4.1 2e-156 521.9 4.1 4.8 5 1 0 6 6 6 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CEG44893.1 - 3.9e-143 476.3 1.1 2.2e-142 473.9 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG44893.1 - 9.4e-125 416.8 11.8 9.4e-125 416.8 11.8 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CEG44893.1 - 1.9e-98 329.0 3.8 2.4e-98 328.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEG44893.1 - 2.8e-92 309.2 0.0 2.6e-90 302.8 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CEG44893.1 - 1.5e-81 272.8 0.6 1.5e-81 272.8 0.6 4.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG44893.1 - 2.3e-72 242.3 4.5 1.1e-69 233.5 0.0 4.2 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG44893.1 - 2.5e-59 199.8 0.1 8e-59 198.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG44893.1 - 5.9e-52 176.8 15.6 1.3e-51 175.7 15.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG44893.1 - 1.9e-40 137.7 0.0 2.9e-39 133.9 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CEG44893.1 - 1.5e-25 89.8 2.0 1.8e-24 86.3 0.1 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CEG44893.1 - 5.3e-19 68.6 1.2 4.7e-09 36.4 0.0 6.3 5 1 1 6 6 6 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CEG44893.1 - 1.1e-18 67.2 1.7 2.6e-17 62.8 0.1 3.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 CEG44893.1 - 9.6e-07 29.1 3.4 0.038 14.3 0.0 6.3 6 0 0 6 6 5 1 AAA domain AAA PF00004.29 CEG44893.1 - 7.7e-05 23.1 2.6 0.16 12.4 0.0 5.1 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEG44893.1 - 0.00038 20.4 0.6 0.59 10.0 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 CEG44893.1 - 0.00046 19.9 1.0 0.47 10.2 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CEG44893.1 - 0.001 19.5 8.4 0.15 12.4 0.0 5.8 5 0 0 5 5 4 1 AAA ATPase domain ABC_tran PF00005.27 CEG44893.1 - 0.0011 19.5 0.1 5.8 7.4 0.0 4.5 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 CEG44893.1 - 0.005 17.2 0.5 13 6.2 0.0 4.7 4 0 0 4 4 4 0 RNA helicase Roc PF08477.13 CEG44893.1 - 0.0059 16.8 0.1 1.9 8.7 0.0 3.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEG44893.1 - 0.0065 16.5 3.9 0.39 10.8 0.1 3.7 3 0 0 3 3 2 1 50S ribosome-binding GTPase TniB PF05621.11 CEG44893.1 - 0.024 14.1 0.2 22 4.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein AAA_19 PF13245.6 CEG44893.1 - 0.058 13.7 0.3 5.6 7.3 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG44893.1 - 0.089 13.3 1.1 18 5.8 0.0 4.7 5 0 0 5 5 3 0 AAA domain AAA_30 PF13604.6 CEG44893.1 - 0.52 10.0 3.0 16 5.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain LacI PF00356.21 CEG44893.1 - 0.84 9.5 4.3 1.6 8.6 0.1 3.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Beach PF02138.18 CEG44894.1 - 4.6e-117 390.3 0.1 7.9e-117 389.5 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 CEG44894.1 - 6.9e-18 64.9 0.5 2.6e-17 63.0 0.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 CEG44894.1 - 6.5e-13 48.6 0.1 1.7e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CEG44894.1 - 0.0035 18.1 0.8 0.2 12.6 0.1 3.4 2 0 0 2 2 2 1 WD domain, G-beta repeat TPR_2 PF07719.17 CEG44895.1 - 1.3e-13 49.9 4.3 0.0073 16.3 0.0 6.3 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44895.1 - 4.5e-13 48.4 2.4 0.0023 17.7 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44895.1 - 3.3e-10 39.4 2.0 0.043 14.1 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44895.1 - 7.6e-10 38.1 3.4 0.17 12.0 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44895.1 - 2.7e-08 34.0 1.5 0.029 14.7 0.0 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG44895.1 - 9e-07 29.2 0.3 0.37 11.7 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44895.1 - 1.8e-06 28.3 7.6 0.0023 18.4 0.0 4.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG44895.1 - 1.4e-05 25.1 0.8 0.06 13.5 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEG44895.1 - 2e-05 24.0 0.7 0.58 9.3 0.0 3.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44895.1 - 4.6e-05 23.5 0.4 1.4 9.4 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44895.1 - 0.00013 22.5 0.1 2.4 8.9 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 CEG44895.1 - 0.0002 20.5 1.0 0.29 10.1 0.1 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CEG44895.1 - 0.00021 21.7 0.6 1.3 9.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 CEG44895.1 - 0.00029 21.3 1.0 0.0013 19.2 0.1 2.4 2 1 0 2 2 2 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 CEG44895.1 - 0.00062 19.9 1.3 2.2 8.6 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEG44895.1 - 0.00097 18.8 0.1 19 5.1 0.0 4.7 5 0 0 5 5 5 0 TPR repeat TPR_MalT PF17874.1 CEG44895.1 - 0.0065 15.9 1.0 0.23 10.8 0.4 3.0 1 1 2 3 3 3 1 MalT-like TPR region DNA_pol_D_N PF18018.1 CEG44895.1 - 0.1 12.7 0.1 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain TOM20_plant PF06552.12 CEG44895.1 - 0.19 11.5 1.2 3.9 7.2 0.0 2.9 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.18 CEG44895.1 - 0.38 10.9 2.8 9.4 6.4 0.0 4.0 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Abhydrolase_4 PF08386.10 CEG44896.1 - 0.14 12.3 0.0 0.66 10.1 0.0 1.9 1 1 0 1 1 1 0 TAP-like protein OSTMP1 PF09777.9 CEG44896.1 - 0.23 10.8 0.7 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Hormone_3 PF00159.18 CEG44898.1 - 0.11 12.6 0.2 4.5 7.4 0.3 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide DED PF01335.21 CEG44898.1 - 6 7.2 8.4 13 6.1 3.9 3.2 2 1 1 3 3 3 0 Death effector domain Pkinase PF00069.25 CEG44899.1 - 1.5e-64 217.9 0.0 1.1e-63 215.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44899.1 - 2.8e-32 112.0 0.0 3.3e-30 105.2 0.0 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase SnoaL_2 PF12680.7 CEG44899.1 - 4e-08 33.8 0.0 1.2e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain PH PF00169.29 CEG44899.1 - 0.0047 17.4 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 PH domain DUF4440 PF14534.6 CEG44899.1 - 0.03 14.7 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Haspin_kinase PF12330.8 CEG44899.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NUDIX PF00293.28 CEG44900.1 - 1.1e-11 44.9 0.2 2.3e-11 43.8 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain Rbsn PF11464.8 CEG44902.1 - 0.0071 16.1 0.3 0.018 14.7 0.3 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain UvrC_HhH_N PF08459.11 CEG44902.1 - 0.046 13.6 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal MFS_1 PF07690.16 CEG44904.1 - 0.0018 17.2 1.4 0.0019 17.2 1.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PP2C PF00481.21 CEG44906.1 - 5.1e-40 137.7 0.0 7.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CEG44906.1 - 0.00072 19.5 0.0 0.036 14.0 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) GAF PF01590.26 CEG44907.1 - 8.3e-06 26.5 0.0 2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain ACBP PF00887.19 CEG44908.1 - 5.6e-28 97.0 3.8 6.2e-28 96.8 3.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TPR_8 PF13181.6 CEG44911.1 - 5e-10 38.8 0.7 0.078 13.2 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEG44911.1 - 1.1e-09 38.3 14.4 0.01 15.8 0.0 7.5 5 2 2 7 7 7 5 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 CEG44911.1 - 1.7e-08 34.6 32.0 0.34 11.8 0.0 12.9 14 2 2 16 16 14 2 Tetratricopeptide repeat Suf PF05843.14 CEG44911.1 - 8.4e-08 32.5 10.6 0.0014 18.7 0.6 5.7 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 CEG44911.1 - 1.4e-06 27.7 8.0 0.2 10.7 0.0 5.4 3 2 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 CEG44911.1 - 6.1e-05 22.8 10.0 9.7 6.6 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG44911.1 - 0.00013 21.3 12.1 0.085 12.1 1.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44911.1 - 0.00044 20.5 3.1 22 5.4 0.0 5.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44911.1 - 0.012 15.6 1.2 5.1 7.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44911.1 - 0.032 14.7 1.6 3.8 8.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG44911.1 - 0.041 13.8 0.7 74 3.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HMW1C_N PF18071.1 CEG44911.1 - 0.1 12.4 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 HMW1C N-terminal TPR_1 PF00515.28 CEG44911.1 - 0.13 12.1 4.9 15 5.6 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat E1_dh PF00676.20 CEG44913.1 - 1.1e-93 313.6 0.0 1.3e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CEG44913.1 - 7e-05 22.7 0.0 0.00049 19.9 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CEG44913.1 - 0.0022 17.3 0.0 0.0076 15.5 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 CEG44913.1 - 0.048 12.5 0.0 0.092 11.5 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain HAD_2 PF13419.6 CEG44914.1 - 6.2e-28 98.1 0.0 9.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEG44914.1 - 2.9e-17 63.7 0.1 1.7e-16 61.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG44914.1 - 2.1e-10 41.3 0.0 3.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CEG44914.1 - 1.6e-05 24.9 0.0 0.0035 17.4 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG44914.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 CEG44914.1 - 0.16 11.7 0.4 6.6 6.4 0.2 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GCP_N_terminal PF17681.1 CEG44915.1 - 3.8e-73 246.8 0.4 6.1e-73 246.1 0.4 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEG44915.1 - 3.7e-60 204.0 6.8 7.6e-60 203.0 6.8 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF1751 PF08551.10 CEG44916.1 - 4.3e-09 36.8 2.8 8.4e-09 35.9 2.8 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CEG44916.1 - 0.02 14.9 9.6 0.016 15.2 7.9 1.7 2 0 0 2 2 2 0 Rhomboid family TPR_2 PF07719.17 CEG44917.1 - 5.3e-10 38.6 7.9 0.0028 17.6 2.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG44917.1 - 8.9e-08 31.6 4.6 0.0036 17.1 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG44917.1 - 2.6e-07 30.9 7.6 0.22 12.5 2.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG44917.1 - 1e-05 25.1 2.9 0.0015 18.1 0.2 3.4 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 CEG44917.1 - 0.00028 21.4 6.1 0.0064 17.0 0.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG44917.1 - 0.00057 20.1 5.8 0.0015 18.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG44917.1 - 0.0006 19.7 6.8 1.4 9.1 0.3 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG44917.1 - 0.0014 19.2 13.8 0.051 14.2 0.6 3.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44917.1 - 0.005 17.1 12.8 0.3 11.4 1.7 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG44917.1 - 0.0077 16.4 0.6 2.9 8.3 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 CEG44917.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 TPR_10 PF13374.6 CEG44917.1 - 0.11 12.4 16.2 0.46 10.4 1.5 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 CEG44917.1 - 0.14 12.6 11.9 24 5.3 11.9 2.3 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 CEG44917.1 - 0.33 11.1 7.4 0.082 13.1 1.4 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 CEG44918.1 - 0.055 13.7 0.1 0.095 13.0 0.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Ninjurin PF04923.12 CEG44921.1 - 0.15 12.0 2.6 0.39 10.7 2.6 1.7 1 1 0 1 1 1 0 Ninjurin GDP_Man_Dehyd PF16363.5 CEG44922.1 - 1e-71 242.1 0.1 2.9e-63 214.3 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEG44922.1 - 4.7e-56 189.9 0.2 4e-55 186.9 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEG44922.1 - 8.3e-21 74.4 0.0 3.2e-17 62.6 0.0 2.7 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CEG44922.1 - 8.9e-18 64.3 0.0 2.4e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEG44922.1 - 1e-17 64.2 0.1 1.1e-14 54.2 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 CEG44922.1 - 1.3e-12 47.5 0.0 2.1e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEG44922.1 - 0.015 15.2 0.0 0.079 12.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding Fzo_mitofusin PF04799.13 CEG44923.1 - 0.0022 17.6 1.9 0.0022 17.6 1.9 6.3 3 2 5 8 8 8 1 fzo-like conserved region HALZ PF02183.18 CEG44923.1 - 0.099 12.9 0.1 0.099 12.9 0.1 6.3 7 1 0 7 7 7 0 Homeobox associated leucine zipper FYVE_2 PF02318.16 CEG44929.1 - 0.0043 17.3 3.2 0.012 15.9 3.2 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 CEG44929.1 - 5.2 7.3 11.8 2.6 8.3 8.7 2.0 2 0 0 2 2 2 0 FYVE zinc finger B56 PF01603.20 CEG44930.1 - 2.2e-18 66.4 0.0 4.8e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Synaptobrevin PF00957.21 CEG44931.1 - 2.5e-31 107.3 0.9 3.6e-31 106.8 0.9 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEG44931.1 - 1.8e-24 85.5 0.1 3.2e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain TMIE PF16038.5 CEG44931.1 - 0.042 13.7 0.9 0.11 12.4 0.9 1.6 1 0 0 1 1 1 0 TMIE protein zf-HIT PF04438.16 CEG44932.1 - 0.00034 20.4 15.6 0.033 14.1 6.4 2.3 2 0 0 2 2 2 2 HIT zinc finger TF_Zn_Ribbon PF08271.12 CEG44932.1 - 0.0028 17.1 1.4 0.089 12.3 0.1 2.6 2 0 0 2 2 2 1 TFIIB zinc-binding DUF2341 PF10102.9 CEG44932.1 - 0.16 12.6 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) SGP PF17228.2 CEG44932.1 - 0.32 11.9 1.8 0.47 11.3 0.8 1.9 2 1 0 2 2 2 0 Sulphur globule protein zf_UBZ PF18439.1 CEG44932.1 - 0.33 10.6 3.5 9.6 5.9 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Mss51 PF13824.6 CEG44932.1 - 1.3 9.2 6.4 9.9 6.3 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 OrfB_Zn_ribbon PF07282.11 CEG44932.1 - 1.6 8.7 7.1 2.7 8.0 7.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 CEG44932.1 - 4.9 7.1 8.3 8.9 6.3 2.8 2.5 1 1 1 2 2 2 0 Halobacterial output domain 2 zf-CCHC_2 PF13696.6 CEG44932.1 - 5.4 6.9 10.2 0.38 10.6 0.9 2.7 2 1 0 2 2 2 0 Zinc knuckle DUF4477 PF14780.6 CEG44933.1 - 2.1e-09 37.3 2.9 3.2e-09 36.7 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) DNA_photolyase PF00875.18 CEG44933.1 - 0.017 15.2 1.2 0.024 14.7 0.7 1.4 2 0 0 2 2 2 0 DNA photolyase DUF3176 PF11374.8 CEG44933.1 - 0.022 15.0 2.7 0.19 11.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3176) Nif11 PF07862.11 CEG44933.1 - 0.095 13.0 0.7 2.1 8.7 0.8 2.5 2 0 0 2 2 2 0 Nif11 domain UQ_con PF00179.26 CEG44934.1 - 3.4e-30 104.5 0.0 5.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2Fe-2S_Ferredox PF11591.8 CEG44934.1 - 3.2 7.7 5.2 7 6.6 5.2 1.6 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide zf-C3H2C3 PF17122.5 CEG44935.1 - 0.007 16.4 1.7 0.007 16.4 1.7 2.2 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 CEG44935.1 - 0.019 14.9 3.3 0.066 13.2 3.3 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 CEG44935.1 - 0.041 13.6 1.4 0.099 12.4 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEG44935.1 - 0.044 13.6 1.0 0.17 11.7 1.0 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG44935.1 - 0.084 13.2 6.4 0.36 11.2 6.4 2.2 1 0 0 1 1 1 0 Ring finger domain Frataxin_Cyay PF01491.16 CEG44935.1 - 0.12 12.4 0.0 0.61 10.2 0.0 2.2 1 0 0 1 1 1 0 Frataxin-like domain zf-rbx1 PF12678.7 CEG44935.1 - 0.35 11.2 3.3 1.3 9.4 3.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEG44935.1 - 0.69 10.0 4.5 4.8 7.3 4.5 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Ureide_permease PF07168.11 CEG44936.1 - 8.9 4.9 9.8 0.12 11.1 0.2 2.3 3 0 0 3 3 3 0 Ureide permease Abhydrolase_6 PF12697.7 CEG44937.1 - 9.1e-08 33.0 0.0 5.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEG44937.1 - 2.6e-06 27.3 0.0 6e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.12 CEG44937.1 - 3.5e-06 26.2 0.1 1.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 CEG44937.1 - 0.00094 18.5 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_Rpb1_7 PF04990.12 CEG44937.1 - 0.073 13.1 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Glyco_transf_41 PF13844.6 CEG44938.1 - 1.4e-18 66.6 0.0 1.1e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 CAP PF00188.26 CEG44940.1 - 1.9e-13 51.4 2.1 2.3e-13 51.1 2.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Talin_middle PF09141.10 CEG44940.1 - 0.047 13.7 0.2 0.074 13.1 0.2 1.3 1 0 0 1 1 1 0 Talin, middle domain ACOX PF01756.19 CEG44941.1 - 1.2e-52 178.1 0.6 6.4e-52 175.7 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEG44941.1 - 3.3e-31 108.4 0.4 1.2e-30 106.6 0.1 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEG44941.1 - 6.9e-13 48.6 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEG44941.1 - 0.00053 20.2 0.4 0.0014 18.8 0.4 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG44941.1 - 0.0042 17.7 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CAP PF00188.26 CEG44942.1 - 9.4e-12 45.9 0.6 1.2e-11 45.5 0.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AIP3 PF03915.13 CEG44942.1 - 0.0061 15.7 0.5 0.0076 15.4 0.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 zf-C4H2 PF10146.9 CEG44942.1 - 0.06 13.7 0.1 0.068 13.5 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF572 PF04502.13 CEG44945.1 - 0.036 13.7 1.9 0.038 13.6 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Trypsin_2 PF13365.6 CEG44946.1 - 0.022 15.7 1.1 0.55 11.1 0.0 2.1 2 0 0 2 2 2 0 Trypsin-like peptidase domain ArgJ PF01960.18 CEG44948.1 - 3.8e-111 371.5 0.0 4.2e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Iwr1 PF08574.10 CEG44949.1 - 3.6e-08 34.3 12.6 3.6e-08 34.3 12.6 3.2 2 1 0 2 2 2 1 Transcription factor Iwr1 Ank_2 PF12796.7 CEG44949.1 - 2.4e-05 24.8 0.0 4.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG44949.1 - 0.016 15.5 0.1 0.11 12.9 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 CEG44949.1 - 0.022 15.2 0.1 0.074 13.5 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CEG44949.1 - 0.022 15.2 0.0 0.057 14.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 CEG44949.1 - 0.078 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CX PF01705.19 CEG44950.1 - 0.0095 16.5 1.2 0.03 14.8 1.2 1.9 1 0 0 1 1 1 1 CX module Dehydratase_MU PF02288.15 CEG44954.1 - 0.046 13.6 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Dehydratase medium subunit Glyco_hydro_5_C PF18564.1 CEG44956.1 - 9.5e-19 67.7 0.1 1.2e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cullin_binding PF03556.15 CEG44957.1 - 4.5e-30 104.6 0.0 7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Cullin binding SAP PF02037.27 CEG44957.1 - 2.8e-10 39.7 0.1 7.9e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 CEG44957.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Glyco_hydro_5_C PF18564.1 CEG44958.1 - 3.5e-19 69.1 0.4 7.1e-19 68.1 0.4 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CEG44958.1 - 2.1e-13 50.4 0.0 5.2e-12 45.8 0.0 2.5 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Anp1 PF03452.14 CEG44959.1 - 0.0012 18.4 1.7 0.0026 17.2 1.7 1.6 1 0 0 1 1 1 1 Anp1 Tup_N PF08581.10 CEG44959.1 - 0.083 13.2 11.5 0.18 12.1 0.1 4.3 4 0 0 4 4 4 0 Tup N-terminal Ribosom_S30AE_C PF16321.5 CEG44959.1 - 0.14 11.9 0.5 0.46 10.2 0.5 1.9 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus DUF3138 PF11336.8 CEG44959.1 - 0.5 8.9 1.5 7.8 5.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Metallophos PF00149.28 CEG44961.1 - 1.5e-31 110.5 0.0 3.1e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 CEG44961.1 - 2.3e-05 24.7 0.8 0.00013 22.4 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG44961.1 - 0.0022 17.4 0.1 0.91 9.2 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG44961.1 - 0.013 15.3 0.6 2 8.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CEG44961.1 - 0.015 15.2 0.1 0.71 10.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain RCC1 PF00415.18 CEG44962.1 - 2.3e-48 162.6 22.4 6e-09 36.4 0.1 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG44962.1 - 7.2e-23 79.8 33.2 3.6e-07 29.8 1.2 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 CEG44962.1 - 8.4e-07 28.6 0.2 1.7e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 SAP domain PhoLip_ATPase_C PF16212.5 CEG44963.1 - 2.4e-63 214.2 17.8 2.4e-63 214.2 17.8 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG44963.1 - 6e-24 83.5 1.8 2.2e-23 81.7 1.8 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CEG44963.1 - 7.5e-16 58.2 0.0 2.4e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEG44963.1 - 2.6e-14 53.0 0.0 7.9e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG44963.1 - 6.1e-11 43.0 1.0 0.00065 20.1 0.1 3.3 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEG44963.1 - 0.0041 16.9 0.4 0.024 14.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG44963.1 - 0.14 12.5 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF202 PF02656.15 CEG44963.1 - 0.2 12.1 2.7 0.49 10.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TMEM208_SND2 PF05620.11 CEG44964.1 - 4e-24 85.3 3.4 1.3e-21 77.1 3.4 2.0 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 COX8 PF02285.15 CEG44964.1 - 0.11 12.4 2.1 0.19 11.6 0.6 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIII RabGAP-TBC PF00566.18 CEG44965.1 - 7.3e-36 123.8 0.0 6.3e-35 120.8 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 CEG44966.1 - 1.2e-35 121.8 17.4 1.1e-13 51.4 0.9 4.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 CEG44966.1 - 2.3e-31 105.0 15.2 2.8e-06 26.5 0.4 6.8 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CEG44966.1 - 2.4e-25 86.2 19.8 3e-05 23.6 0.5 7.8 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 CEG44966.1 - 3.5e-25 87.6 11.6 1.9e-10 40.4 0.3 6.0 5 1 1 6 6 6 3 EF-hand domain pair Metallophos PF00149.28 CEG44966.1 - 9.2e-25 88.3 0.0 3.4e-24 86.5 0.0 1.9 2 0 0 2 2 1 1 Calcineurin-like phosphoesterase EF-hand_5 PF13202.6 CEG44966.1 - 1.5e-21 74.9 9.9 0.0012 18.2 0.1 5.9 5 0 0 5 5 5 5 EF hand CAP_GLY PF01302.25 CEG44966.1 - 4.7e-13 49.0 0.0 1.4e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_4 PF12763.7 CEG44966.1 - 8.7e-09 35.3 5.9 0.0095 15.9 0.0 4.5 3 2 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CEG44966.1 - 3.2e-08 34.4 4.9 0.0062 17.4 0.3 3.9 3 1 1 4 4 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG44966.1 - 9.3e-08 32.4 0.3 0.18 12.1 0.0 4.6 4 1 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CEG44966.1 - 2.3e-07 30.9 4.1 0.0076 16.2 0.0 4.2 4 0 0 4 4 4 2 Caleosin related protein PPP5 PF08321.12 CEG44966.1 - 4.7e-05 23.6 0.1 0.0003 21.0 0.0 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region EF-hand_10 PF14788.6 CEG44966.1 - 0.0046 16.8 3.1 0.13 12.1 0.2 3.2 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CEG44966.1 - 0.0071 16.7 0.3 0.1 12.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain IQ PF00612.27 CEG44966.1 - 0.008 15.9 0.3 0.022 14.5 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Dockerin_1 PF00404.18 CEG44966.1 - 0.076 13.2 0.7 6.6 7.0 0.1 2.9 3 0 0 3 3 2 0 Dockerin type I domain HIGH_NTase1_ass PF16581.5 CEG44966.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region IL1_propep PF02394.16 CEG44966.1 - 0.082 13.8 0.0 0.39 11.6 0.0 2.1 1 0 0 1 1 1 0 Interleukin-1 propeptide L27_N PF09060.10 CEG44966.1 - 5.6 7.1 6.5 52 4.0 0.1 4.3 5 0 0 5 5 5 0 L27_N Myb_DNA-binding PF00249.31 CEG44967.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG44967.1 - 0.0014 18.9 0.2 0.025 14.8 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain CDC45 PF02724.14 CEG44967.1 - 0.38 9.0 11.3 0.54 8.5 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.12 CEG44967.1 - 1.9 6.4 9.0 2.6 5.9 9.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 CEG44967.1 - 2.7 8.0 6.5 4.4 7.3 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CEG44967.1 - 4.6 5.2 10.1 6 4.9 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 CEG44968.1 - 8.3e-69 231.9 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG44968.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CEG44968.1 - 1.1e-13 51.2 0.1 2.9e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CEG44968.1 - 2.9e-06 26.8 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CEG44968.1 - 0.011 16.5 0.5 0.043 14.5 0.5 2.1 1 1 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 CEG44968.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG44968.1 - 0.096 12.6 0.1 0.25 11.2 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CEG44968.1 - 0.1 12.2 0.0 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_5_C PF18564.1 CEG44969.1 - 1.1e-16 61.1 0.1 2e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CEG44969.1 - 2.9e-12 46.6 0.0 5.5e-10 39.1 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_61 PF03443.14 CEG44970.1 - 0.61 10.0 5.5 1.5 8.7 0.3 2.9 2 1 1 3 3 3 0 Glycosyl hydrolase family 61 DGCR6 PF07324.11 CEG44971.1 - 6.3e-08 32.5 0.9 1e-07 31.8 0.9 1.2 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein TPR_14 PF13428.6 CEG44971.1 - 1.7e-07 31.5 1.6 0.016 16.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Suf PF05843.14 CEG44971.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 2.9 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 CEG44971.1 - 0.017 15.2 1.0 3.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG44971.1 - 0.077 13.5 0.1 0.49 10.9 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG44971.1 - 0.078 13.3 0.1 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEG44971.1 - 0.08 12.9 1.2 1.9 8.5 0.4 2.8 1 1 2 3 3 3 0 Mad3/BUB1 homology region 1 A2M PF00207.22 CEG44971.1 - 0.15 12.0 0.6 1.1 9.2 0.1 2.4 1 1 1 2 2 2 0 Alpha-2-macroglobulin family LCAT PF02450.15 CEG44972.1 - 1.9e-75 254.5 0.0 2.8e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 CEG44972.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Alfin PF12165.8 CEG44973.1 - 0.077 12.7 0.0 0.077 12.7 0.0 1.0 1 0 0 1 1 1 0 Alfin Retrotran_gag_2 PF14223.6 CEG44975.1 - 7.1e-25 87.3 0.0 8.2e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Kinesin PF00225.23 CEG44976.1 - 7.9e-92 307.7 0.0 1.6e-91 306.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG44976.1 - 1.4e-24 86.7 0.0 3.7e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF3452 PF11934.8 CEG44976.1 - 0.059 12.9 2.0 0.23 11.0 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) AAA_16 PF13191.6 CEG44976.1 - 0.065 13.6 0.1 0.065 13.6 0.1 2.1 3 0 0 3 3 3 0 AAA ATPase domain RNase_PH PF01138.21 CEG44977.1 - 2.9e-17 63.4 1.2 5.2e-17 62.6 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG44977.1 - 7.7e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gemin7 PF11095.8 CEG44977.1 - 0.059 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) TFIIA_gamma_N PF02268.16 CEG44978.1 - 0.00057 19.9 0.8 0.0011 18.9 0.2 1.8 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF2795 PF11387.8 CEG44978.1 - 0.055 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) HTH_23 PF13384.6 CEG44983.1 - 0.0002 21.0 0.2 0.00033 20.3 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 CEG44983.1 - 0.0015 18.2 0.4 0.0032 17.1 0.4 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 CEG44983.1 - 0.0034 17.4 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 CEG44983.1 - 0.0059 16.7 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CEG44983.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_4 PF13613.6 CEG44983.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.16 CEG44983.1 - 0.08 12.5 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 zf-C3HC4_2 PF13923.6 CEG44984.1 - 7.1e-07 29.0 1.2 7.1e-07 29.0 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG44984.1 - 1.1e-05 25.6 4.5 3.1e-05 24.2 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG44984.1 - 0.00013 22.2 10.8 0.0021 18.4 10.8 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEG44984.1 - 0.00021 21.2 6.8 0.00072 19.5 6.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG44984.1 - 0.00037 20.3 6.3 0.0013 18.6 6.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG44984.1 - 0.0031 17.2 0.5 0.0031 17.2 0.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEG44984.1 - 0.0038 17.2 2.6 0.0092 16.0 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger PX PF00787.24 CEG44984.1 - 0.016 15.2 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 PX domain zf-ANAPC11 PF12861.7 CEG44984.1 - 0.039 14.0 0.3 0.039 14.0 0.3 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CEG44984.1 - 0.05 13.8 0.6 0.05 13.8 0.6 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG44984.1 - 0.86 9.5 6.4 0.14 12.0 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CEG44984.1 - 0.92 9.4 5.6 1.5 8.7 3.7 2.3 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CEG44984.1 - 1.7 8.5 8.3 0.1 12.4 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CEG44984.1 - 2 8.4 8.1 4.8 7.2 2.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 CEG44984.1 - 2.5 8.5 8.4 0.24 11.7 2.2 2.3 2 0 0 2 2 2 0 RING-like domain PX PF00787.24 CEG44985.1 - 0.0021 18.0 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 PX domain LptE PF04390.12 CEG44985.1 - 0.024 15.3 0.0 0.042 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly DUF3435 PF11917.8 CEG44985.1 - 0.043 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) PX PF00787.24 CEG44986.1 - 0.00078 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 PX domain PFEMP PF03011.15 CEG44986.1 - 0.041 14.6 0.6 0.07 13.8 0.6 1.3 1 0 0 1 1 1 0 PFEMP DBL domain PIG-S PF10510.9 CEG44987.1 - 0.019 13.8 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein eIF-5a PF01287.20 CEG44989.1 - 4.7e-27 93.9 0.1 7.5e-27 93.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CEG44989.1 - 5.3e-05 23.2 0.1 8.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Cofilin_ADF PF00241.20 CEG44990.1 - 5.2e-23 81.1 0.1 6.7e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-HC5HC2H_2 PF13832.6 CEG44991.1 - 3.6e-11 43.2 3.9 3.6e-11 43.2 3.9 4.4 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEG44991.1 - 3.7e-10 39.9 3.5 3.7e-10 39.9 3.5 4.2 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 CEG44991.1 - 0.00076 19.3 4.6 0.00076 19.3 4.6 4.2 4 1 0 4 4 4 1 PHD-finger PDEase_I PF00233.19 CEG44992.1 - 2.2e-78 263.3 0.1 3.4e-78 262.6 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 CEG44992.1 - 7.2e-08 31.9 12.7 1.3e-07 31.1 12.7 1.3 1 0 0 1 1 1 1 Ion transport protein DUF667 PF05018.13 CEG44993.1 - 2.2e-27 96.0 0.0 4.5e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF667) FAR1 PF03101.15 CEG44993.1 - 4.7e-07 30.4 22.4 0.008 16.8 0.5 5.3 5 1 0 5 5 5 3 FAR1 DNA-binding domain DUF4646 PF15496.6 CEG44993.1 - 0.037 14.6 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Cauli_VI PF01693.16 CEG44993.1 - 0.065 13.5 0.0 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Caulimovirus viroplasmin DUF3319 PF11782.8 CEG44993.1 - 0.17 11.9 0.4 46 4.1 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3319) CUB_2 PF02408.20 CEG44993.1 - 0.56 10.0 4.4 0.33 10.7 1.5 2.2 2 0 0 2 2 2 0 CUB-like domain Ribosomal_L29 PF00831.23 CEG44995.1 - 9.5e-19 67.1 1.0 9.5e-19 67.1 1.0 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 CEG44995.1 - 0.016 15.3 1.3 0.016 15.3 1.3 2.4 2 1 0 2 2 2 0 TolA binding protein trimerisation Trp_leader2 PF08056.11 CEG44995.1 - 0.08 12.9 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Tryptophan operon leader peptide Prominin PF05478.11 CEG44995.1 - 0.098 10.6 2.6 0.1 10.5 2.6 1.0 1 0 0 1 1 1 0 Prominin ESM4 PF15952.5 CEG44995.1 - 0.17 12.3 4.9 0.21 12.0 4.9 1.3 1 1 0 1 1 1 0 Enhancer of split M4 family PRKCSH-like PF12999.7 CEG44995.1 - 0.8 9.5 3.0 0.78 9.5 2.2 1.4 1 1 0 1 1 1 0 Glucosidase II beta subunit-like CCDC-167 PF15188.6 CEG44995.1 - 0.95 9.8 7.9 4.1 7.8 0.5 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 RVT_1 PF00078.27 CEG44996.1 - 1.8e-17 63.6 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HECT PF00632.25 CEG44997.1 - 4.8e-96 321.9 0.2 9.2e-96 320.9 0.1 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 CEG44997.1 - 1.9e-21 74.7 11.5 7.6e-07 28.4 0.4 4.3 3 1 1 4 4 4 3 Ubiquitin binding region UBA PF00627.31 CEG44997.1 - 9.7e-06 25.4 0.0 2.5e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain PPP4R2 PF09184.11 CEG44997.1 - 0.09 12.4 26.2 0.011 15.4 20.3 2.2 2 0 0 2 2 2 0 PPP4R2 DNA_pol_phi PF04931.13 CEG44997.1 - 3.2 5.7 36.3 8.2 4.4 0.4 2.8 2 0 0 2 2 2 0 DNA polymerase phi STAG PF08514.11 CEG44999.1 - 1.2e-28 99.3 1.1 7.1e-28 96.8 0.1 3.0 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 CEG44999.1 - 0.00019 21.4 0.6 8.5 6.9 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CEG44999.1 - 0.0035 17.7 0.0 0.17 12.3 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CEG44999.1 - 0.0096 16.0 2.0 0.027 14.5 0.2 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinesin PF00225.23 CEG45000.1 - 6.5e-107 357.3 0.7 6.5e-107 357.3 0.7 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG45000.1 - 1.2e-45 155.1 0.4 3.2e-45 153.7 0.4 1.8 1 0 0 1 1 1 1 Microtubule binding HALZ PF02183.18 CEG45000.1 - 0.09 13.0 13.3 0.21 11.8 1.9 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper RrnaAD PF00398.20 CEG45001.1 - 5.5e-61 205.9 0.1 1.2e-60 204.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DEAD PF00270.29 CEG45001.1 - 5.6e-45 153.3 0.1 1.7e-44 151.7 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG45001.1 - 3.2e-29 101.5 6.4 6.9e-29 100.4 0.2 4.2 4 1 0 4 4 4 1 Helicase conserved C-terminal domain Methyltransf_25 PF13649.6 CEG45001.1 - 3.1e-08 34.2 0.0 2.3e-07 31.4 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG45001.1 - 3.9e-08 33.8 0.0 1.7e-06 28.6 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain AAA_22 PF13401.6 CEG45001.1 - 0.00052 20.3 0.1 0.0015 18.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain Methyltransf_12 PF08242.12 CEG45001.1 - 0.00069 20.3 2.0 0.0024 18.6 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain NodS PF05401.11 CEG45001.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 CEG45001.1 - 0.0065 16.3 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CEG45001.1 - 0.027 14.3 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CEG45001.1 - 0.029 14.0 0.3 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MTS PF05175.14 CEG45001.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain TPR_12 PF13424.6 CEG45004.1 - 1.1e-08 35.2 0.8 0.0076 16.5 0.1 4.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG45004.1 - 6e-05 22.6 4.8 0.0027 17.1 0.6 2.7 2 2 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 CEG45004.1 - 0.038 13.9 9.4 0.17 11.8 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG45004.1 - 0.043 13.9 4.9 0.33 11.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CHASE8 PF17152.4 CEG45004.1 - 0.089 13.0 0.5 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 Periplasmic sensor domain TPR_4 PF07721.14 CEG45004.1 - 0.1 13.3 0.0 9.2 7.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45004.1 - 1.4 9.3 3.7 3.3 8.1 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45004.1 - 2.1 8.9 9.0 2.7 8.6 0.3 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG45004.1 - 5.4 7.7 8.0 22 5.8 0.0 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 CEG45005.1 - 1.9e-24 85.3 69.2 2.4e-08 33.8 0.3 16.0 17 0 0 17 17 17 7 HAT (Half-A-TPR) repeat Suf PF05843.14 CEG45005.1 - 1.1e-20 74.8 22.5 4.3e-07 30.2 5.9 6.2 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEG45005.1 - 4.6e-16 58.1 24.5 0.026 15.3 0.0 11.3 6 3 5 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45005.1 - 1.1e-11 45.1 1.3 0.37 11.3 0.0 6.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEG45005.1 - 1.8e-08 34.9 14.8 0.49 11.1 0.0 7.6 7 1 2 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG45005.1 - 2.5e-08 33.7 0.6 0.00073 19.7 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG45005.1 - 3.3e-08 33.0 17.2 2.4 8.5 0.1 10.2 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG45005.1 - 1.2e-07 31.8 10.0 0.00078 19.6 0.1 5.6 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45005.1 - 9.8e-05 22.6 7.4 16 5.9 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45005.1 - 0.00012 22.0 8.0 2.4 8.6 0.2 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEG45005.1 - 0.00015 21.7 26.5 0.023 14.7 0.8 7.5 6 4 2 8 8 8 1 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 CEG45005.1 - 0.43 10.7 26.2 0.92 9.6 0.1 7.3 4 3 4 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 CEG45005.1 - 0.99 10.2 21.2 46 5.0 0.1 9.2 9 1 0 9 9 9 0 Tetratricopeptide repeat Cytochrom_C1 PF02167.15 CEG45009.1 - 9e-90 300.2 0.0 1.1e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CEG45009.1 - 0.00072 19.8 0.2 0.002 18.4 0.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CEG45009.1 - 0.037 15.1 0.2 0.12 13.6 0.2 1.9 1 1 0 1 1 1 0 Cytochrome c RNA_pol_A_bac PF01000.26 CEG45010.1 - 6.8e-31 107.0 0.0 1.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEG45010.1 - 5e-24 83.5 0.0 8.8e-24 82.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CEG45010.1 - 0.02 15.0 0.9 0.041 14.0 0.9 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEG45010.1 - 0.094 13.3 1.0 0.22 12.2 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF1242 PF06842.12 CEG45011.1 - 1e-17 63.6 1.5 1.6e-17 63.0 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Mito_carr PF00153.27 CEG45012.1 - 4.1e-31 106.7 10.0 3.8e-18 65.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 CEG45014.1 - 4.3e-43 146.9 10.3 3.8e-30 104.8 0.2 3.3 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEG45014.1 - 1.3e-28 100.0 3.9 7.3e-26 91.0 0.0 4.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEG45014.1 - 1.9e-18 67.5 2.7 3.6e-17 63.4 2.7 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG45014.1 - 2.4e-16 59.6 0.0 7.7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEG45014.1 - 7.3e-16 57.6 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG45014.1 - 0.0032 17.3 0.3 0.0057 16.4 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RVT_2 PF07727.14 CEG45015.1 - 4.6e-47 160.7 1.5 5.5e-47 160.5 1.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG45015.1 - 0.0027 17.3 0.6 0.0063 16.0 0.2 1.7 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_6 PF18452.1 CEG45015.1 - 0.17 11.4 1.2 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain HSP70 PF00012.20 CEG45016.1 - 5.2e-184 612.8 0.4 6.3e-184 612.5 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG45016.1 - 7.4e-17 61.1 0.0 8.1e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CEG45016.1 - 0.0055 15.7 0.2 0.048 12.6 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CEG45016.1 - 0.021 14.1 0.2 0.043 13.1 0.1 1.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 CEG45016.1 - 0.053 13.0 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 CEG45016.1 - 0.057 13.9 0.4 13 6.3 0.0 2.6 2 2 0 2 2 2 0 Cell division protein FtsA FGGY_C PF02782.16 CEG45016.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Actin PF00022.19 CEG45016.1 - 0.12 10.9 0.2 2.8 6.5 0.2 2.8 1 1 0 1 1 1 0 Actin Cu2_monooxygen PF01082.20 CEG45017.1 - 0.025 14.8 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain T2SSG PF08334.11 CEG45017.1 - 0.11 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G MtN3_slv PF03083.16 CEG45021.1 - 5.4e-31 106.5 4.6 1.7e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 CEG45021.1 - 0.00042 20.0 2.2 2.7 7.8 0.1 3.5 3 0 0 3 3 3 2 PQ loop repeat O-antigen_lig PF13425.6 CEG45021.1 - 0.011 14.6 0.4 0.4 9.4 0.4 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MARVEL PF01284.23 CEG45021.1 - 0.36 10.9 5.1 15 5.6 4.0 3.0 2 1 0 2 2 2 0 Membrane-associating domain Imp-YgjV PF10688.9 CEG45021.1 - 5.1 6.9 8.3 5.5 6.8 3.1 2.8 1 1 1 2 2 2 0 Bacterial inner membrane protein DUF1627 PF07789.12 CEG45022.1 - 3.5e-07 30.0 0.3 6.4e-07 29.2 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1627) Fe_dep_repress PF01325.19 CEG45022.1 - 0.0048 17.1 0.0 0.021 15.0 0.0 2.1 2 1 1 3 3 3 1 Iron dependent repressor, N-terminal DNA binding domain HTH_AsnC-type PF13404.6 CEG45022.1 - 0.0054 16.5 1.5 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Dimerisation PF08100.11 CEG45022.1 - 0.041 13.9 2.4 14 5.8 0.0 3.6 4 0 0 4 4 4 0 Dimerisation domain Rrf2 PF02082.20 CEG45022.1 - 0.082 13.3 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator HTH_27 PF13463.6 CEG45022.1 - 0.12 12.8 0.3 12 6.5 0.0 2.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain QueH PF02677.14 CEG45023.1 - 1.7e-64 217.2 0.6 1.9e-64 216.9 0.6 1.0 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH SieB PF14163.6 CEG45028.1 - 0.099 12.1 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Dimer_Tnp_hAT PF05699.14 CEG45029.1 - 2.1e-13 49.9 0.5 4.1e-13 48.9 0.1 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SSF PF00474.17 CEG45030.1 - 4.6e-18 65.3 2.4 4.6e-18 65.3 2.4 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family Tubulin PF00091.25 CEG45030.1 - 0.19 11.9 0.2 0.39 10.9 0.1 1.5 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain PGG PF13962.6 CEG45030.1 - 5.1 6.9 13.1 1.5 8.7 1.1 3.6 4 0 0 4 4 4 0 Domain of unknown function Syntaxin-18_N PF10496.9 CEG45031.1 - 0.65 10.3 7.4 0.27 11.5 1.1 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4100 PF13352.6 CEG45031.1 - 2 8.2 8.0 0.51 10.1 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) TonB_dep_Rec PF00593.24 CEG45032.1 - 1.8e-07 31.4 1.1 2.2e-07 31.1 1.1 1.0 1 0 0 1 1 1 1 TonB dependent receptor DUF4756 PF15948.5 CEG45032.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) GH131_N PF18271.1 CEG45033.1 - 7.3e-41 140.5 0.0 8.8e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain OpgC_C PF10129.9 CEG45033.1 - 0.19 10.6 0.2 0.3 9.9 0.2 1.2 1 0 0 1 1 1 0 OpgC protein Pectate_lyase PF03211.13 CEG45034.1 - 2.7e-67 226.2 9.9 3.4e-67 225.9 9.9 1.0 1 0 0 1 1 1 1 Pectate lyase gag_pre-integrs PF13976.6 CEG45035.1 - 5.8e-06 26.1 0.0 8.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain CSD PF00313.22 CEG45035.1 - 0.043 13.7 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain YbaB_DNA_bd PF02575.16 CEG45035.1 - 0.078 13.2 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family PID_2 PF14719.6 CEG45036.1 - 0.071 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF4413 PF14372.6 CEG45039.1 - 9.7e-05 22.7 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) YacG PF03884.14 CEG45040.1 - 0.075 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG dbPDZ_assoc PF16610.5 CEG45041.1 - 0.28 11.4 6.9 0.4 10.9 6.9 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Amino_oxidase PF01593.24 CEG45043.1 - 8.9e-16 58.2 0.1 1e-15 58.0 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEG45043.1 - 1e-12 48.1 0.2 1.3e-12 47.8 0.2 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG45043.1 - 4e-07 29.9 0.2 4.4e-07 29.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEG45043.1 - 8.9e-07 28.3 0.7 1.1e-06 28.0 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CEG45043.1 - 2.7e-06 26.4 0.3 3.4e-06 26.0 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 CEG45043.1 - 5.3e-06 25.7 0.3 7.1e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CEG45043.1 - 4.4e-05 22.9 0.1 4.8e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEG45043.1 - 5.4e-05 22.5 0.0 6.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CEG45043.1 - 0.00028 20.3 0.2 0.00035 19.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEG45043.1 - 0.00054 19.1 0.3 0.00054 19.1 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CEG45043.1 - 0.00092 19.7 1.0 0.0018 18.8 0.8 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEG45043.1 - 0.0031 16.9 0.2 0.0031 16.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEG45043.1 - 0.0042 17.1 0.1 0.0045 17.0 0.1 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CEG45043.1 - 0.0048 16.2 0.4 0.0065 15.8 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 CEG45043.1 - 0.023 14.9 0.3 0.037 14.3 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 CEG45043.1 - 0.062 13.4 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IQ PF00612.27 CEG45044.1 - 9.3e-08 31.2 12.8 0.0066 16.1 0.5 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif A_thal_3526 PF09713.10 CEG45044.1 - 0.078 13.2 4.2 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) DUF155 PF02582.14 CEG45045.1 - 2.3e-50 171.1 0.0 3.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CEG45045.1 - 0.022 15.2 0.1 0.054 14.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Leptin PF02024.15 CEG45045.1 - 0.045 13.5 0.2 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 Leptin Peptidase_M76 PF09768.9 CEG45046.1 - 3e-58 196.4 12.0 3.5e-58 196.1 12.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 CEG45046.1 - 0.018 15.4 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Effector protein Propeptide_C25 PF08126.11 CEG45046.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Propeptide_C25 SprT-like PF10263.9 CEG45046.1 - 0.22 11.4 3.2 0.29 11.0 1.9 1.8 1 1 1 2 2 2 0 SprT-like family GCV_H PF01597.19 CEG45047.1 - 3e-07 30.3 0.0 1.4e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Glycine cleavage H-protein zf-CCCH PF00642.24 CEG45047.1 - 3.8e-06 26.7 4.3 7.9e-06 25.7 4.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG45047.1 - 0.2 11.5 3.1 0.4 10.6 3.1 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger SecY PF00344.20 CEG45049.1 - 1.3e-73 247.9 15.7 1.7e-73 247.5 15.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CEG45049.1 - 1.4e-18 66.5 1.8 1.4e-18 66.4 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p SMC_N PF02463.19 CEG45051.1 - 5.6e-22 78.3 21.7 5.6e-22 78.3 21.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEG45051.1 - 1.5e-20 73.7 0.0 5e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain EzrA PF06160.12 CEG45051.1 - 3.9e-05 22.1 26.6 3.9e-05 22.1 26.6 5.7 3 2 2 5 5 5 2 Septation ring formation regulator, EzrA LacI PF00356.21 CEG45051.1 - 0.046 13.5 1.0 14 5.5 0.3 3.4 2 1 1 3 3 3 0 Bacterial regulatory proteins, lacI family La PF05383.17 CEG45052.1 - 2.1e-19 69.3 1.3 3.2e-19 68.7 1.3 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CEG45052.1 - 0.0034 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CEG45052.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DUF1279 PF06916.13 CEG45055.1 - 0.0019 18.7 0.3 0.019 15.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Peptidase_C69 PF03577.15 CEG45056.1 - 0.056 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 Myosin_head PF00063.21 CEG45057.1 - 1.9e-220 733.6 0.0 2.4e-220 733.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 CEG45057.1 - 5.6e-17 61.9 0.3 1.5e-16 60.5 0.3 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 CEG45057.1 - 5.2e-05 23.4 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin IQ PF00612.27 CEG45057.1 - 0.0033 17.1 9.5 0.88 9.5 0.0 3.7 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA_16 PF13191.6 CEG45057.1 - 0.015 15.7 0.2 0.059 13.7 0.0 2.1 2 1 0 3 3 3 0 AAA ATPase domain CAMSAP_CH PF11971.8 CEG45057.1 - 0.066 13.0 0.1 0.23 11.3 0.1 1.9 1 0 0 1 1 1 0 CAMSAP CH domain AAA_22 PF13401.6 CEG45057.1 - 0.1 12.9 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEG45057.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain E2F_TDP PF02319.20 CEG45058.1 - 2.7e-13 49.8 0.0 4.9e-07 29.7 0.0 3.0 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUSP PF06337.12 CEG45058.1 - 1.7e-06 28.6 0.0 5.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 DUSP domain FUSC PF04632.12 CEG45059.1 - 0.48 8.9 0.9 0.67 8.4 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_CG PF14542.6 CEG45060.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NB PF04159.13 CEG45062.1 - 0.06 13.4 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 NB glycoprotein DUF4212 PF13937.6 CEG45062.1 - 0.26 11.7 1.6 0.33 11.4 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) RVT_2 PF07727.14 CEG45064.1 - 0.0013 18.5 0.1 0.0016 18.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 CEG45068.1 - 3.2e-41 142.1 0.1 4.2e-41 141.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEG45068.1 - 2.7e-21 75.8 0.2 6.5e-21 74.5 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain NYAP_N PF15439.6 CEG45069.1 - 0.25 10.5 0.8 0.28 10.4 0.8 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DNA_pol_B_2 PF03175.13 CEG45071.1 - 5.5e-12 45.3 0.0 5.3e-09 35.5 0.0 2.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Mannosyl_trans3 PF11051.8 CEG45076.1 - 1.1e-25 90.6 0.1 2.2e-25 89.6 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Elicitin PF00964.17 CEG45081.1 - 1.7e-18 66.5 4.4 2.8e-18 65.8 4.4 1.4 1 0 0 1 1 1 1 Elicitin Ribosomal_L19 PF01245.20 CEG45083.1 - 3.3e-23 81.8 0.2 4.5e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 SRP_TPR_like PF17004.5 CEG45084.1 - 7.9e-12 45.2 5.8 7.9e-12 45.2 5.8 3.4 2 1 0 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 CEG45084.1 - 2.2e-07 30.5 22.6 3.6 7.9 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45084.1 - 1.5e-06 28.5 14.7 0.27 12.1 0.4 8.0 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45084.1 - 2.9e-06 27.5 23.5 0.24 11.7 2.2 7.9 8 1 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45084.1 - 0.00015 22.2 19.6 9.9 6.8 0.0 8.2 7 2 1 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG45084.1 - 0.00029 21.0 14.5 0.0074 16.5 1.4 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.12 CEG45084.1 - 0.00062 20.2 6.6 0.00062 20.2 6.6 2.9 2 1 0 2 2 2 1 SRP72 RNA-binding domain TPR_6 PF13174.6 CEG45084.1 - 0.00093 19.7 22.3 6.7 7.6 0.5 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat Glycos_transf_3 PF00591.21 CEG45084.1 - 0.026 14.1 0.1 2.7 7.5 0.0 2.4 1 1 0 2 2 2 0 Glycosyl transferase family, a/b domain TPR_7 PF13176.6 CEG45084.1 - 0.072 13.2 10.8 1.5 9.0 0.8 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG45084.1 - 0.25 11.2 19.1 6.6 6.7 0.0 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG45084.1 - 0.93 9.5 9.8 2.3 8.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Fer2_3 PF13085.6 CEG45085.1 - 0.053 13.5 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain fn3 PF00041.21 CEG45086.1 - 1.5e-58 195.1 30.8 6.3e-13 48.9 0.0 14.3 14 0 0 14 14 14 12 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CEG45086.1 - 6.4e-12 45.9 22.0 0.00011 22.7 0.0 8.9 11 0 0 11 11 11 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CEG45086.1 - 2e-09 37.7 0.0 15 6.1 0.0 8.5 9 0 0 9 9 9 2 Uncharacterised conserved protein (DUF2369) POTRA_1 PF08478.10 CEG45086.1 - 0.00034 20.9 0.0 37 4.7 0.0 5.4 5 0 0 5 5 5 0 POTRA domain, FtsQ-type Uroplakin_II PF07353.12 CEG45086.1 - 0.0017 17.9 6.5 0.46 10.0 0.0 4.8 5 0 0 5 5 5 2 Uroplakin II Interfer-bind PF09294.10 CEG45086.1 - 0.0063 16.8 0.0 22 5.4 0.0 4.1 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 CEG45087.1 - 1.2e-29 102.5 18.7 4.7e-05 23.6 0.2 9.4 8 1 0 8 8 8 7 Fibronectin type III domain Gp_dh_C PF02800.20 CEG45089.1 - 6.1e-27 94.1 0.0 1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEG45089.1 - 0.0002 21.6 0.1 0.0007 19.9 0.0 1.9 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CEG45089.1 - 0.0084 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4856 PF16148.5 CEG45091.1 - 0.056 12.4 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) TRP PF06011.12 CEG45093.1 - 4.2e-36 124.6 15.6 8.1e-36 123.7 15.6 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF485 PF04341.12 CEG45093.1 - 0.025 14.5 2.0 0.13 12.2 2.0 2.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 RuvC PF02075.17 CEG45094.1 - 0.016 15.1 0.0 0.21 11.5 0.0 2.5 2 1 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC DUF5544 PF17698.1 CEG45094.1 - 0.022 14.8 0.8 0.04 14.0 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5544) DUF2024 PF09630.10 CEG45094.1 - 0.023 14.6 0.1 0.071 13.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) CPSase_L_D2 PF02786.17 CEG45095.1 - 1.3e-113 377.7 0.7 1e-81 273.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CEG45095.1 - 2.3e-51 172.9 0.0 5.2e-51 171.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEG45095.1 - 6.3e-44 150.0 0.0 3.3e-41 141.1 0.0 2.8 3 0 0 3 3 3 2 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CEG45095.1 - 3.4e-38 130.7 0.1 1e-37 129.2 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CEG45095.1 - 3.1e-18 65.9 0.6 6.9e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CEG45095.1 - 4.2e-18 65.6 1.3 5.6e-09 35.8 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 CEG45095.1 - 6.8e-16 58.2 0.0 8.9e-15 54.7 0.0 2.9 3 0 0 3 3 3 1 MGS-like domain ATPgrasp_Ter PF15632.6 CEG45095.1 - 2e-12 47.0 0.0 2.2e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CEG45095.1 - 5.7e-08 33.0 0.1 0.0014 18.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 CEG45095.1 - 2e-07 31.0 0.8 5.4e-05 23.1 0.1 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 CEG45095.1 - 4.4e-06 26.4 0.0 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.13 CEG45095.1 - 0.00031 20.5 1.3 0.015 15.0 0.2 3.3 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_5 PF13549.6 CEG45095.1 - 0.017 14.6 0.0 8.2 5.8 0.0 3.2 3 0 0 3 3 3 0 ATP-grasp domain Peptidase_M17_N PF02789.17 CEG45095.1 - 0.082 12.8 0.1 0.35 10.7 0.1 2.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain AP_endonuc_2 PF01261.24 CEG45095.1 - 0.15 11.5 0.0 1.1 8.7 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Ras PF00071.22 CEG45096.1 - 2.8e-35 121.3 0.5 3.5e-35 121.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG45096.1 - 3.4e-25 88.6 0.0 5.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG45096.1 - 1.1e-07 31.4 0.1 1.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG45096.1 - 1.4e-05 24.6 0.5 1.7e-05 24.3 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CEG45096.1 - 0.00097 18.1 0.1 0.052 12.4 0.0 2.1 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 CEG45096.1 - 0.002 17.7 0.3 0.015 14.8 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEG45096.1 - 0.0021 17.5 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG45096.1 - 0.038 14.1 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG45096.1 - 0.099 12.2 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 CEG45096.1 - 0.16 11.1 2.4 0.57 9.3 0.1 2.3 1 1 2 3 3 3 0 G-protein alpha subunit AA_kinase PF00696.28 CEG45097.1 - 1.3e-23 83.8 0.6 2.7e-23 82.8 0.6 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 CEG45097.1 - 6e-20 71.9 0.0 6.2e-19 68.6 0.0 2.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CEG45097.1 - 0.0022 18.1 0.0 0.0072 16.4 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus vATP-synt_E PF01991.18 CEG45097.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit IL13 PF03487.13 CEG45098.1 - 1.5 8.6 3.9 1.2 9.0 0.1 2.4 3 0 0 3 3 3 0 Interleukin-13 PIG-X PF08320.12 CEG45099.1 - 8.7e-24 84.6 0.0 1.2e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 NBP1 PF08537.10 CEG45100.1 - 0.087 12.2 6.2 0.14 11.5 6.1 1.4 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 FKBP_C PF00254.28 CEG45101.1 - 9.8e-30 102.7 0.0 4.5e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CEG45101.1 - 2.2e-11 44.2 0.0 2.2e-11 44.2 0.0 2.6 2 1 1 3 3 3 1 Nucleoplasmin-like domain GREB1 PF15782.5 CEG45101.1 - 0.74 6.9 7.8 0.94 6.5 7.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4239 PF14023.6 CEG45101.1 - 1.4 8.6 2.8 2 8.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ATP_bind_3 PF01171.20 CEG45102.1 - 4.2e-44 150.5 0.0 9.9e-44 149.3 0.0 1.6 1 1 0 1 1 1 1 PP-loop family Ank_5 PF13857.6 CEG45102.1 - 0.051 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PAPS_reduct PF01507.19 CEG45102.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Enolase_C PF00113.22 CEG45103.1 - 2.8e-147 489.7 1.2 3.6e-147 489.3 1.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CEG45103.1 - 4e-53 179.1 0.0 9.3e-53 177.9 0.0 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CEG45103.1 - 2.9e-09 36.8 0.0 5e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CEG45103.1 - 7.3e-06 25.3 1.1 1e-05 24.8 0.5 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus PCI PF01399.27 CEG45104.1 - 1.3e-16 61.0 1.0 4e-16 59.4 1.0 1.9 1 0 0 1 1 1 1 PCI domain SEN1_N PF12726.7 CEG45104.1 - 0.063 11.5 0.0 0.085 11.1 0.0 1.2 1 0 0 1 1 1 0 SEN1 N terminal Pro_isomerase PF00160.21 CEG45105.1 - 8.1e-19 68.4 0.0 1.5e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glutaredoxin PF00462.24 CEG45105.1 - 2.4e-18 66.1 0.1 1.7e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_2 PF13098.6 CEG45105.1 - 0.0013 19.2 0.0 0.036 14.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain DUF836 PF05768.14 CEG45105.1 - 0.0082 16.5 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 CEG45108.1 - 2.6e-06 27.7 0.0 4.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_14 PF18402.1 CEG45108.1 - 0.00016 21.8 0.0 0.00019 21.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 CEG45108.1 - 0.00021 21.2 0.0 0.012 15.4 0.0 2.3 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Cas_Csm6 PF09659.10 CEG45108.1 - 0.088 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Kdo_hydroxy PF11004.8 CEG45108.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Aminotran_1_2 PF00155.21 CEG45109.1 - 1.4e-89 300.8 0.0 3.8e-89 299.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Thioredoxin_4 PF13462.6 CEG45109.1 - 0.00017 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin RVT_2 PF07727.14 CEG45111.1 - 6.4e-37 127.5 0.9 7.3e-37 127.3 0.9 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fmp27_GFWDK PF10347.9 CEG45113.1 - 0.057 13.5 1.9 4.3 7.4 0.2 2.5 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain KH_4 PF13083.6 CEG45115.1 - 0.042 13.7 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 KH domain Phospholamban PF04272.14 CEG45117.1 - 0.26 10.8 2.4 0.55 9.7 2.4 1.7 1 1 0 1 1 1 0 Phospholamban Glyco_hydro_3 PF00933.21 CEG45119.1 - 4.6e-53 180.7 0.0 6.2e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEG45119.1 - 4.9e-40 137.7 0.0 9.5e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CEG45119.1 - 7.5e-13 48.4 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.23 CEG45119.1 - 0.15 11.8 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain PX PF00787.24 CEG45124.1 - 8e-08 32.3 0.7 1.3e-07 31.5 0.7 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.24 CEG45125.1 - 1.3e-08 34.9 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.24 CEG45126.1 - 1.7e-13 50.5 0.1 3.5e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 PX domain PX PF00787.24 CEG45127.1 - 7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 PX domain EF-hand_7 PF13499.6 CEG45128.1 - 2.6e-33 114.3 10.0 2.6e-14 53.4 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 CEG45128.1 - 3.3e-33 110.7 17.9 1.8e-07 30.2 0.4 6.7 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 CEG45128.1 - 3.9e-29 98.1 8.1 1e-05 25.0 0.0 6.6 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 CEG45128.1 - 1.4e-18 66.4 12.6 3.5e-07 29.9 0.3 5.5 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 CEG45128.1 - 2e-16 58.6 15.8 0.00037 19.9 0.2 6.4 6 0 0 6 6 6 4 EF hand C2 PF00168.30 CEG45128.1 - 3.2e-15 56.3 0.1 1.4e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_9 PF14658.6 CEG45128.1 - 1.4e-08 34.9 0.2 0.11 12.8 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG45128.1 - 2e-05 24.8 0.1 2 8.7 0.0 3.2 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG45128.1 - 2.8e-05 24.0 2.0 2.8 7.9 0.1 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand MotA_activ PF09114.10 CEG45128.1 - 0.19 11.9 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Transcription factor MotA, activation domain FYVE_2 PF02318.16 CEG45130.1 - 0.0003 21.0 9.1 0.0003 21.0 9.1 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 CEG45130.1 - 0.061 13.5 14.9 0.15 12.2 14.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger TRP PF06011.12 CEG45131.1 - 1.6e-16 60.1 20.4 6.5e-16 58.1 20.4 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Tmemb_9 PF05434.11 CEG45131.1 - 1.1 9.2 5.5 30 4.5 0.4 3.8 3 0 0 3 3 3 0 TMEM9 PFK PF00365.20 CEG45133.1 - 2.6e-59 200.9 0.1 3.5e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CEG45133.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MatE PF01554.18 CEG45134.1 - 0.00013 21.7 0.7 0.00013 21.7 0.7 2.8 3 0 0 3 3 3 1 MatE RXLR PF16810.5 CEG45136.1 - 0.0028 18.1 5.4 0.0089 16.5 5.4 1.7 1 1 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity ENTH PF01417.20 CEG45140.1 - 6.4e-33 113.5 0.0 8e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CEG45140.1 - 0.0028 16.7 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CEG45140.1 - 0.0041 17.0 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 VHS domain Retrotrans_gag PF03732.17 CEG45142.1 - 2.7e-08 34.0 0.0 7.8e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein XPG_N PF00752.17 CEG45143.1 - 2.2e-30 105.1 0.0 6.6e-30 103.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEG45143.1 - 2.4e-25 88.7 0.1 3.7e-24 84.9 0.0 3.3 2 0 0 2 2 2 1 XPG I-region TAL_effector PF03377.13 CEG45143.1 - 0.12 12.7 0.0 0.56 10.6 0.0 2.1 1 0 0 1 1 1 0 TAL effector repeat DUF4200 PF13863.6 CEG45144.1 - 2.1e-32 112.0 22.9 2.1e-32 112.0 22.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) DivIC PF04977.15 CEG45144.1 - 0.0056 16.4 2.2 0.0056 16.4 2.2 3.4 4 0 0 4 4 4 1 Septum formation initiator WWE PF02825.20 CEG45144.1 - 0.025 15.2 0.5 2.3 8.9 0.5 2.8 2 0 0 2 2 2 0 WWE domain TolA_bind_tri PF16331.5 CEG45144.1 - 0.037 14.1 8.5 0.087 12.9 0.4 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation Bap31_Bap29_C PF18035.1 CEG45144.1 - 0.06 13.4 3.1 0.14 12.2 1.8 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Peptidase_M26_N PF05342.14 CEG45144.1 - 0.12 11.8 2.2 0.2 11.0 2.2 1.3 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Mod_r PF07200.13 CEG45144.1 - 0.39 10.8 23.2 0.32 11.1 0.9 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.19 CEG45144.1 - 1.3 6.8 9.2 1.6 6.6 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4349 PF14257.6 CEG45144.1 - 1.8 8.0 12.7 6.7 6.1 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) NPV_P10 PF05531.12 CEG45144.1 - 1.9 9.0 4.9 5 7.7 1.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MALT1_Ig PF18703.1 CEG45144.1 - 2.6 8.1 8.6 2.6 8.1 2.9 2.3 1 1 1 2 2 2 0 MALT1 Ig-like domain Ank_2 PF12796.7 CEG45145.1 - 1.2e-38 131.5 7.4 6.9e-13 49.0 1.7 4.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45145.1 - 8.4e-37 125.1 5.6 5.9e-10 39.5 0.0 5.7 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CEG45145.1 - 1.9e-26 91.3 10.9 7.7e-05 23.0 0.3 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 CEG45145.1 - 1.4e-22 77.3 5.7 0.018 15.6 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 CEG45145.1 - 4.2e-21 74.7 6.3 1.9e-06 28.0 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) WW PF00397.26 CEG45145.1 - 1.3e-08 34.8 2.5 4.3e-08 33.1 2.5 1.9 1 0 0 1 1 1 1 WW domain Sdh_cyt PF01127.22 CEG45148.1 - 3.8e-10 39.9 0.1 5.4e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RyR PF02026.16 CEG45150.1 - 6.9e-44 148.0 0.1 6.5e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 RyR domain Pkinase PF00069.25 CEG45150.1 - 5.8e-41 140.6 0.0 2.2e-39 135.5 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45150.1 - 1.6e-19 70.2 0.0 4e-10 39.4 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase PH PF00169.29 CEG45150.1 - 1.9e-05 25.1 0.0 6.7e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CEG45150.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.6 CEG45150.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 CEG45150.1 - 0.064 13.7 0.5 0.37 11.2 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 CEG45150.1 - 0.14 11.8 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CEG45150.1 - 0.15 11.4 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DUF948 PF06103.11 CEG45151.1 - 0.099 12.9 11.8 6.6 7.1 0.1 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Phosphoesterase PF04185.14 CEG45151.1 - 0.14 11.3 0.2 1.3 8.1 0.4 2.1 2 0 0 2 2 2 0 Phosphoesterase family Repressor_Mnt PF11423.8 CEG45151.1 - 0.26 11.1 3.1 1.1 9.1 0.1 2.8 2 0 0 2 2 2 0 Regulatory protein Mnt Pox_A_type_inc PF04508.12 CEG45151.1 - 0.54 10.2 7.0 43 4.2 0.0 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 CEG45151.1 - 1 9.1 42.4 0.91 9.3 13.0 3.3 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH TFR_dimer PF04253.15 CEG45151.1 - 9.4 6.4 8.3 5.1 7.2 0.5 3.4 4 1 0 4 4 4 0 Transferrin receptor-like dimerisation domain Cortex-I_coil PF09304.10 CEG45152.1 - 0.001 19.2 7.2 0.001 19.2 7.2 4.1 2 1 1 3 3 3 1 Cortexillin I, coiled coil DivIC PF04977.15 CEG45152.1 - 0.016 14.9 4.4 0.016 14.9 4.4 5.4 3 3 3 6 6 6 0 Septum formation initiator GRDB PF07355.12 CEG45152.1 - 0.096 11.9 0.1 0.096 11.9 0.1 2.6 3 0 0 3 3 3 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) KLRAQ PF10205.9 CEG45152.1 - 0.22 11.8 49.3 0.036 14.3 15.4 4.6 1 1 3 4 4 4 0 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 CEG45152.1 - 2.2 8.5 57.2 0.63 10.2 25.3 4.0 1 1 3 4 4 4 0 Tropomyosin like Trimer_CC PF08954.11 CEG45152.1 - 2.4 7.8 22.9 0.21 11.2 4.5 4.9 3 1 0 3 3 3 0 Trimerisation motif DUF5517 PF17639.2 CEG45152.1 - 4.4 7.7 11.6 0.1 12.9 2.8 2.7 2 2 2 4 4 4 0 Family of unknown function (DUF5517) RNA_binding PF01877.17 CEG45152.1 - 4.7 7.5 14.9 0.11 12.8 3.8 2.9 1 1 1 2 2 2 0 RNA binding Zn_Tnp_IS91 PF14319.6 CEG45153.1 - 0.21 11.7 8.0 0.15 12.1 5.8 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF702 PF05142.12 CEG45153.1 - 6.5 7.2 15.4 15 6.1 15.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF702) ubiquitin PF00240.23 CEG45154.1 - 3.3e-21 74.8 0.1 5.2e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CEG45154.1 - 1.7e-09 37.3 0.2 1.7e-09 37.3 0.2 2.5 2 0 0 2 2 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CEG45154.1 - 2.1e-08 33.9 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 CEG45154.1 - 2.9e-06 27.1 64.2 0.00045 20.1 6.8 5.5 2 2 1 4 4 4 2 STI1 domain Ubiquitin_4 PF18036.1 CEG45154.1 - 0.00041 20.3 0.2 0.088 12.9 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain LPD22 PF18834.1 CEG45154.1 - 0.0026 17.9 8.0 0.19 11.9 0.9 3.6 2 1 1 3 3 3 1 Large polyvalent protein associated domain 22 ScsC_N PF18312.1 CEG45154.1 - 0.0062 16.3 6.1 7 6.6 0.1 4.7 5 0 0 5 5 5 1 Copper resistance protein ScsC N-terminal domain Nif11 PF07862.11 CEG45154.1 - 0.026 14.8 0.2 0.81 10.0 0.0 3.1 3 1 0 3 3 3 0 Nif11 domain Rad60-SLD_2 PF13881.6 CEG45154.1 - 0.04 14.0 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Hydrolase_4 PF12146.8 CEG45154.1 - 0.069 12.4 2.1 0.79 8.9 0.2 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TACC_C PF05010.14 CEG45154.1 - 0.24 11.2 7.3 0.17 11.7 1.5 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BSD PF03909.17 CEG45154.1 - 0.35 10.9 6.1 14 5.8 0.1 3.6 3 0 0 3 3 3 0 BSD domain Speriolin_C PF15059.6 CEG45154.1 - 0.38 10.9 1.4 5.9 7.0 0.0 2.8 2 1 1 3 3 3 0 Speriolin C-terminus Dynactin_p22 PF07426.11 CEG45154.1 - 0.43 10.4 3.3 5.6 6.8 0.2 2.5 2 1 0 2 2 2 0 Dynactin subunit p22 XPC-binding PF09280.11 CEG45154.1 - 0.65 9.8 54.1 1.4 8.8 10.7 5.8 2 2 2 4 4 4 0 XPC-binding domain FANCI_S2 PF14676.6 CEG45155.1 - 0.00034 21.0 4.0 0.00035 20.9 0.3 2.7 3 0 0 3 3 3 1 FANCI solenoid 2 MLIP PF15274.6 CEG45156.1 - 0.11 12.3 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Muscular LMNA-interacting protein LRR_9 PF14580.6 CEG45157.1 - 7.8e-15 54.8 2.6 1.5e-14 53.9 2.6 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEG45157.1 - 1.1e-14 54.3 10.8 6.6e-07 29.6 0.1 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG45157.1 - 2.2e-05 24.1 12.7 0.00017 21.2 6.2 3.1 2 1 1 3 3 3 2 Leucine rich repeat PIEZO PF15917.5 CEG45157.1 - 0.0041 16.6 0.6 0.0058 16.1 0.6 1.2 1 0 0 1 1 1 1 Piezo Herpes_UL6 PF01763.16 CEG45157.1 - 0.011 14.3 0.7 0.014 13.9 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like LRR_1 PF00560.33 CEG45157.1 - 1.3 9.9 8.2 18 6.3 1.1 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CEG45157.1 - 2.8 8.2 5.1 9.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat KELK PF15796.5 CEG45157.1 - 5.7 7.5 10.7 1.4 9.4 2.8 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TIG PF01833.24 CEG45159.1 - 2.6e-07 30.6 4.5 0.0037 17.3 1.7 3.6 2 1 0 2 2 2 2 IPT/TIG domain UcrQ PF02939.16 CEG45160.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 UcrQ family DUF465 PF04325.13 CEG45160.1 - 0.04 14.0 3.3 2.5 8.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) ABC_membrane PF00664.23 CEG45162.1 - 3e-48 164.8 27.8 6.1e-34 117.9 5.3 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG45162.1 - 9.9e-48 162.1 0.0 1.1e-27 97.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG45162.1 - 8.2e-13 48.8 0.1 0.00031 20.7 0.0 4.5 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG45162.1 - 3.6e-09 36.4 0.0 0.032 13.7 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEG45162.1 - 3e-07 30.8 0.1 0.059 13.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CEG45162.1 - 5.2e-07 29.7 0.0 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG45162.1 - 1.2e-06 28.5 0.1 0.056 13.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CEG45162.1 - 2.3e-06 27.7 0.0 0.082 13.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 CEG45162.1 - 2.7e-06 27.9 0.1 0.042 14.2 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEG45162.1 - 7.2e-06 25.7 0.1 0.079 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG45162.1 - 1.4e-05 25.7 0.1 0.011 16.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEG45162.1 - 4.8e-05 22.5 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 CEG45162.1 - 0.00028 20.5 0.1 0.52 9.9 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CEG45162.1 - 0.00047 20.7 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CEG45162.1 - 0.0023 17.2 0.0 0.6 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CEG45162.1 - 0.0067 16.0 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Guanylate_kin PF00625.21 CEG45162.1 - 0.0068 16.1 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 Guanylate kinase AAA_25 PF13481.6 CEG45162.1 - 0.012 15.3 0.0 5.2 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEG45162.1 - 0.014 14.8 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CEG45162.1 - 0.016 15.4 0.0 5.6 7.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 CEG45162.1 - 0.022 14.5 0.8 9.8 5.9 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 CEG45162.1 - 0.029 13.3 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 CEG45162.1 - 0.029 14.8 0.0 6.9 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CEG45162.1 - 0.031 14.0 0.1 2.1 8.0 0.0 3.1 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.13 CEG45162.1 - 0.052 12.7 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 CEG45162.1 - 0.1 11.8 0.0 5 6.3 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 CEG45162.1 - 0.11 12.8 0.0 26 5.0 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CEG45162.1 - 0.13 11.2 0.1 0.3 10.0 0.0 1.6 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 CEG45162.1 - 0.16 11.5 0.0 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain dNK PF01712.19 CEG45162.1 - 0.17 11.7 0.0 19 5.0 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Septin PF00735.18 CEG45162.1 - 0.17 11.1 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Septin Epiglycanin_C PF14654.6 CEG45163.1 - 0.12 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region TPR_19 PF14559.6 CEG45164.1 - 0.00021 21.8 0.4 0.0018 18.7 0.4 2.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG45164.1 - 0.0017 18.6 0.2 0.095 13.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45164.1 - 0.0028 17.7 1.1 3.7 8.0 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45164.1 - 0.0068 16.7 6.1 0.71 10.2 2.7 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45164.1 - 0.17 12.8 8.5 0.15 13.0 0.6 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1771 PF08590.10 CEG45164.1 - 0.57 10.6 16.4 0.22 12.0 2.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1771) TPR_1 PF00515.28 CEG45164.1 - 0.7 9.8 5.9 7.7 6.5 1.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45164.1 - 1.6 8.9 4.3 38 4.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 CEG45165.1 - 4.9e-29 100.7 27.6 2.8e-06 27.9 0.2 8.7 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG45165.1 - 9.1e-24 82.7 40.8 1.6e-06 27.8 2.5 7.7 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CEG45165.1 - 1.2e-23 83.4 6.4 5.1e-13 49.2 0.1 4.1 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 CEG45165.1 - 0.055 13.6 0.3 0.22 11.6 0.3 2.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch Methyltranf_PUA PF13636.6 CEG45165.1 - 0.19 11.7 0.0 0.56 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF BT1 PF03092.16 CEG45166.1 - 6.3e-11 41.2 13.9 1.2e-10 40.3 2.0 2.2 1 1 0 2 2 2 2 BT1 family DHHC PF01529.20 CEG45170.1 - 2.4e-21 76.2 6.3 2.4e-21 76.2 6.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-tcix PF14952.6 CEG45170.1 - 0.11 12.2 3.4 0.11 12.2 2.2 1.6 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding VEFS-Box PF09733.9 CEG45170.1 - 0.11 12.3 1.5 0.18 11.6 1.5 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein ELO PF01151.18 CEG45174.1 - 5.1e-51 173.6 24.9 6.4e-51 173.3 24.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 CEG45174.1 - 0.25 11.5 1.5 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 CCSMST1 family ELO PF01151.18 CEG45175.1 - 4.8e-49 167.1 28.3 5.7e-49 166.9 28.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_A22B PF04258.13 CEG45176.1 - 1.9e-49 168.7 6.5 1.2e-48 166.2 6.5 2.0 1 1 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 CEG45176.1 - 0.021 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 PA domain CBP_BcsF PF11120.8 CEG45176.1 - 0.15 12.2 0.6 0.7 10.1 0.6 2.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF NOP19 PF10863.8 CEG45176.1 - 0.17 11.7 0.2 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 Nucleolar protein 19 60KD_IMP PF02096.20 CEG45176.1 - 1.4 8.8 3.8 67 3.3 0.0 3.1 3 0 0 3 3 3 0 60Kd inner membrane protein Lustrin_cystein PF14625.6 CEG45176.1 - 7.3 7.1 10.8 0.45 10.9 4.2 2.5 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain LptC PF06835.13 CEG45178.1 - 0.0036 16.9 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related DUF1829 PF08862.10 CEG45178.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Ank_2 PF12796.7 CEG45179.1 - 1.3e-34 118.6 29.0 5.5e-07 30.1 0.1 6.5 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45179.1 - 2.9e-32 110.6 21.0 1.9e-06 28.3 0.1 9.6 9 1 0 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG45179.1 - 8.8e-24 83.3 20.4 0.035 14.5 0.0 11.1 6 3 6 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG45179.1 - 3.5e-15 54.6 15.0 0.37 11.5 0.1 12.4 11 2 2 13 13 13 3 Ankyrin repeat DUF1987 PF09345.10 CEG45179.1 - 0.057 13.1 0.0 15 5.3 0.0 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF1987) SBP_bac_6 PF13343.6 CEG45179.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cas9_Topo PF17894.1 CEG45179.1 - 0.4 10.8 2.3 82 3.4 0.0 4.4 5 1 0 5 5 5 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Ank PF00023.30 CEG45179.1 - 0.67 10.5 12.4 1.9e+02 2.7 0.0 7.8 8 2 0 8 8 8 0 Ankyrin repeat T6SS_VasJ PF16989.5 CEG45179.1 - 0.79 9.2 4.2 6.6 6.1 0.4 3.5 3 1 1 4 4 4 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Ndc1_Nup PF09531.10 CEG45180.1 - 0.8 8.3 18.7 0.99 8.0 18.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BBS2_Mid PF14783.6 CEG45182.1 - 0.00018 21.5 0.0 0.24 11.5 0.0 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF1359 PF07097.11 CEG45182.1 - 0.0081 16.4 0.8 0.075 13.3 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1359) FliS_cochap PF16522.5 CEG45182.1 - 0.048 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 VCBS PF13517.6 CEG45182.1 - 0.1 13.2 0.0 1.4 9.6 0.0 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF364 PF04016.12 CEG45182.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative heavy-metal chelation Cupin_8 PF13621.6 CEG45183.1 - 5.6e-43 147.5 0.0 9.5e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEG45183.1 - 8e-11 42.0 0.2 4.5e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 CEG45183.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain FAM25 PF15825.5 CEG45183.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 FAM25 family JmjC PF02373.22 CEG45183.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.8 1 1 0 1 1 1 0 JmjC domain, hydroxylase Mur_ligase_M PF08245.12 CEG45184.1 - 1.8e-10 41.2 0.0 3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CEG45184.1 - 1.2e-05 25.5 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain PA28_beta PF02252.18 CEG45185.1 - 3.1e-28 98.3 1.2 2.1e-19 69.7 0.1 2.5 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Cas_Cmr5 PF09701.10 CEG45185.1 - 0.017 15.4 0.8 0.06 13.6 0.4 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Myb_DNA-binding PF00249.31 CEG45186.1 - 5.4e-30 103.3 6.6 2.7e-14 53.1 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG45186.1 - 2.2e-22 79.1 5.6 3e-17 62.6 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CEG45186.1 - 0.0013 18.8 0.6 0.0074 16.5 0.1 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 CEG45186.1 - 0.0025 18.2 0.3 0.0025 18.2 0.3 3.2 4 1 0 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG45186.1 - 0.0065 16.3 2.7 0.02 14.8 0.2 2.7 3 0 0 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 CEG45186.1 - 0.0069 16.4 0.0 0.026 14.5 0.0 2.0 1 0 0 1 1 1 1 SLIDE Myb_DNA-bind_2 PF08914.11 CEG45186.1 - 2.2 8.5 6.1 0.34 11.1 0.7 2.4 1 1 1 2 2 2 0 Rap1 Myb domain MbeD_MobD PF04899.12 CEG45187.1 - 0.048 13.8 0.3 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 MbeD/MobD like EF-hand_1 PF00036.32 CEG45192.1 - 0.0042 16.5 0.0 0.016 14.7 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CEG45192.1 - 0.018 15.5 1.6 0.09 13.2 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CEG45192.1 - 0.02 14.4 0.1 0.065 12.8 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_4 PF12763.7 CEG45192.1 - 0.11 12.5 0.0 0.42 10.6 0.0 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SAM_decarbox PF01536.16 CEG45193.1 - 5.7e-106 354.5 0.0 6.4e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PRKCSH PF07915.13 CEG45194.1 - 8.2e-20 71.6 0.1 2.8e-14 53.9 0.1 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CEG45194.1 - 1.2e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HSF_DNA-bind PF00447.17 CEG45199.1 - 1.6e-22 80.0 0.1 2.9e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Hist_deacetyl PF00850.19 CEG45202.1 - 1.6e-59 201.9 0.0 2.8e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Ank_5 PF13857.6 CEG45202.1 - 2.9e-09 37.0 0.4 8.6e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG45202.1 - 3.8e-09 37.0 0.5 0.0013 19.3 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG45202.1 - 7.5e-07 29.0 3.0 0.69 10.7 0.0 6.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 CEG45202.1 - 2e-05 25.1 0.4 0.87 10.3 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG45202.1 - 0.48 11.0 4.0 49 4.6 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat PhoLip_ATPase_C PF16212.5 CEG45204.1 - 9.2e-66 222.1 26.4 9.2e-66 222.1 26.4 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG45204.1 - 2.2e-21 75.3 2.3 7.8e-21 73.6 2.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEG45204.1 - 7.1e-10 38.9 0.0 6.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG45204.1 - 9.1e-09 35.9 0.1 0.014 15.7 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG45204.1 - 9.7e-05 22.0 0.0 0.00054 19.5 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG45204.1 - 0.0042 16.9 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 CEG45205.1 - 2.9e-57 194.1 0.0 3.5e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAP2 PF01569.21 CEG45207.1 - 4.4e-24 84.8 3.3 7.8e-24 84.0 3.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CEG45207.1 - 0.0016 18.2 1.3 1 9.0 0.5 2.4 2 0 0 2 2 2 2 PAP2 superfamily zf-CCCH_4 PF18044.1 CEG45208.1 - 3e-16 58.8 35.6 1.7e-08 34.0 3.3 4.0 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEG45208.1 - 2e-13 49.9 30.6 2e-06 27.6 6.2 4.0 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 CEG45208.1 - 9e-13 47.8 25.7 2.4e-06 27.3 1.4 3.8 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEG45208.1 - 1.6e-10 41.7 11.2 2.7e-06 28.0 0.4 3.3 2 1 1 3 3 3 3 Torus domain zf-RING_2 PF13639.6 CEG45208.1 - 8.8e-08 32.4 9.5 8.8e-08 32.4 9.5 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEG45208.1 - 8e-06 25.6 8.4 2.1e-05 24.3 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG45208.1 - 1.7e-05 24.7 8.3 6e-05 22.9 8.3 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG45208.1 - 2.1e-05 24.3 6.2 7.5e-05 22.5 6.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 CEG45208.1 - 0.0011 19.4 26.7 0.0061 17.0 1.9 4.1 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 CEG45208.1 - 0.0021 18.0 8.2 0.006 16.6 8.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 CEG45208.1 - 0.0058 16.4 7.8 0.017 14.9 7.8 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CEG45208.1 - 0.006 16.7 5.4 0.006 16.7 5.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEG45208.1 - 0.054 13.3 9.9 0.25 11.2 9.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG45208.1 - 0.53 10.1 8.8 1.7 8.5 8.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 CEG45208.1 - 0.68 9.8 14.9 0.12 12.2 8.6 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH_3 PF15663.5 CEG45208.1 - 2.3 8.4 11.6 2.7 8.2 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger containing family Anoctamin PF04547.12 CEG45209.1 - 6.8e-111 371.3 19.9 8.3e-111 371.0 19.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CEG45209.1 - 1.8e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF3938 PF13074.6 CEG45209.1 - 5.7 7.2 6.5 0.93 9.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF3535 PF12054.8 CEG45210.1 - 0.075 12.3 0.0 0.084 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) YtxH PF12732.7 CEG45210.1 - 0.1 13.2 3.2 0.24 11.9 3.2 1.7 1 1 0 1 1 1 0 YtxH-like protein UPF0020 PF01170.18 CEG45213.1 - 1.2e-13 51.2 0.6 3.9e-12 46.3 0.0 3.1 3 1 0 3 3 3 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CEG45213.1 - 5.9e-06 26.2 0.1 0.002 17.8 0.0 2.4 2 0 0 2 2 2 2 DNA methylase bZIP_2 PF07716.15 CEG45213.1 - 0.0052 16.8 0.5 0.015 15.4 0.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEG45213.1 - 0.0095 16.0 1.9 0.024 14.7 1.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor Cwf_Cwc_15 PF04889.12 CEG45213.1 - 0.012 15.4 1.6 0.021 14.6 1.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_P4B PF03292.14 CEG45213.1 - 0.016 13.5 3.0 0.023 13.0 3.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein MethyltransfD12 PF02086.15 CEG45213.1 - 0.019 14.7 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 CEG45213.1 - 0.022 14.3 0.1 6.9 6.2 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase small domain Met_10 PF02475.16 CEG45213.1 - 0.054 13.2 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein N6-adenineMlase PF10237.9 CEG45213.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.8 2 1 0 2 2 2 0 Probable N6-adenine methyltransferase PAH PF02671.21 CEG45215.1 - 0.0011 19.0 0.2 0.0025 17.9 0.2 1.6 1 0 0 1 1 1 1 Paired amphipathic helix repeat Plant_NMP1 PF06694.11 CEG45215.1 - 0.01 14.9 0.2 0.072 12.2 0.0 2.3 3 0 0 3 3 3 0 Plant nuclear matrix protein 1 (NMP1) PPARgamma_N PF12577.8 CEG45215.1 - 0.37 11.5 2.5 8.9 7.0 0.4 2.7 2 0 0 2 2 2 0 PPAR gamma N-terminal region Nop16 PF09420.10 CEG45216.1 - 1.1e-22 81.2 10.2 1.4e-14 54.7 1.7 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 RRT14 PF17075.5 CEG45216.1 - 0.046 13.9 4.3 0.15 12.1 0.4 2.1 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 Myb_DNA-bind_6 PF13921.6 CEG45216.1 - 0.07 13.4 0.4 0.2 11.9 0.4 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RNase_J_C PF17770.1 CEG45216.1 - 0.091 13.8 1.0 0.21 12.7 0.4 1.9 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Myb_DNA-binding PF00249.31 CEG45216.1 - 0.1 12.8 0.4 0.48 10.7 0.1 2.2 1 1 1 2 2 2 0 Myb-like DNA-binding domain Mur_ligase_M PF08245.12 CEG45217.1 - 6e-06 26.4 0.0 0.00012 22.1 0.0 2.8 1 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CEG45217.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain RVT_2 PF07727.14 CEG45218.1 - 2.5e-49 168.1 1.1 2.8e-49 168.0 1.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Salt_tol_Pase PF09506.10 CEG45219.1 - 0.07 11.9 0.4 0.083 11.6 0.4 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Lin-8 PF03353.15 CEG45221.1 - 0.013 15.1 2.8 0.014 15.0 2.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 CEG45221.1 - 0.073 12.3 0.7 0.073 12.3 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RHINO PF15319.6 CEG45221.1 - 0.34 10.9 4.9 0.38 10.8 4.9 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein SAPS PF04499.15 CEG45221.1 - 0.42 9.3 6.4 0.45 9.2 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 CEG45221.1 - 1 7.8 13.4 1.1 7.7 13.4 1.0 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CEG45221.1 - 1.2 6.2 7.7 1.3 6.1 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CEG45221.1 - 1.7 7.4 15.6 1.8 7.3 15.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Miga PF10265.9 CEG45221.1 - 1.7 7.5 5.1 1.8 7.5 5.1 1.0 1 0 0 1 1 1 0 Mitoguardin SOG2 PF10428.9 CEG45221.1 - 2 7.5 17.4 2.2 7.4 17.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 CEG45221.1 - 2.5 7.4 6.0 2.7 7.3 6.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Med13_C PF06333.12 CEG45221.1 - 2.9 7.1 13.1 3.3 6.9 13.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Hid1 PF12722.7 CEG45221.1 - 3.3 5.7 5.8 3.4 5.7 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 CEG45221.1 - 3.9 7.3 16.6 4.4 7.1 16.6 1.0 1 0 0 1 1 1 0 SPX domain Peroxin-3 PF04882.12 CEG45221.1 - 7.8 5.4 10.0 8.6 5.2 10.0 1.1 1 0 0 1 1 1 0 Peroxin-3 Myb_DNA-bind_7 PF15963.5 CEG45222.1 - 2.8e-24 84.8 0.2 7e-24 83.5 0.2 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CEG45222.1 - 0.0028 17.8 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain KH_1 PF00013.29 CEG45223.1 - 7.5e-63 208.3 14.5 1.8e-18 66.1 0.7 4.2 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CEG45223.1 - 2.8e-15 55.9 3.4 5.6e-05 22.9 0.2 4.2 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 CEG45223.1 - 7.4e-12 44.9 9.6 0.00045 20.0 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CEG45223.1 - 6.6e-05 22.9 7.6 3.3 7.9 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain UPF0547 PF10571.9 CEG45224.1 - 0.066 13.3 0.3 0.066 13.3 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Elicitin PF00964.17 CEG45225.1 - 1.9e-16 59.9 1.3 4.9e-16 58.6 1.3 1.7 1 0 0 1 1 1 1 Elicitin DUF5305 PF17231.2 CEG45225.1 - 0.054 12.9 0.6 0.11 11.9 0.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Rhomboid PF01694.22 CEG45227.1 - 2.9e-25 89.0 9.9 4.8e-25 88.3 9.9 1.3 1 0 0 1 1 1 1 Rhomboid family PIG-Y PF15159.6 CEG45227.1 - 0.079 13.9 0.6 0.91 10.5 0.0 2.7 3 1 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y RabGAP-TBC PF00566.18 CEG45228.1 - 7.3e-19 68.3 0.0 1.8e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 CEG45228.1 - 9.3e-09 35.8 0.5 0.00033 21.1 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 CEG45228.1 - 0.0013 19.0 0.2 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DUF515 PF04415.12 CEG45228.1 - 0.28 9.5 1.7 20 3.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) MS_channel PF00924.18 CEG45229.1 - 0.0025 17.4 0.1 0.0043 16.6 0.1 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel Tagatose_6_P_K PF08013.11 CEG45229.1 - 0.13 10.9 0.6 0.15 10.7 0.6 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Kazal_2 PF07648.15 CEG45230.1 - 1.5e-09 37.8 5.5 3e-09 36.9 5.5 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG45230.1 - 1.1e-07 31.8 5.0 1.8e-07 31.1 5.0 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_8 PF13833.6 CEG45231.1 - 1e-08 34.9 4.6 2.7e-07 30.3 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG45231.1 - 0.00011 21.4 9.4 0.034 13.7 1.4 3.7 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CEG45231.1 - 0.00021 21.6 4.8 0.00097 19.5 0.7 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_11 PF08976.11 CEG45231.1 - 0.025 15.5 0.2 0.029 15.2 0.2 1.3 1 0 0 1 1 1 0 EF-hand domain DUF2353 PF09789.9 CEG45231.1 - 0.046 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Gp-FAR-1 PF05823.12 CEG45231.1 - 0.077 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) EF-hand_6 PF13405.6 CEG45231.1 - 0.3 11.1 3.2 9.3 6.5 0.2 3.3 3 1 0 3 3 3 0 EF-hand domain MCU PF04678.13 CEG45232.1 - 1e-28 100.6 3.5 2.6e-28 99.3 3.5 1.8 1 1 0 1 1 1 1 Mitochondrial calcium uniporter V-ATPase_G PF03179.15 CEG45233.1 - 1e-23 83.9 13.5 1.1e-23 83.7 13.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CEG45233.1 - 0.00095 18.6 7.7 0.00095 18.6 7.7 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF3552) OmpH PF03938.14 CEG45233.1 - 0.005 17.2 12.9 0.006 16.9 12.9 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) V-ATPase_G_2 PF16999.5 CEG45233.1 - 0.1 13.0 13.2 1.9 8.9 0.7 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CEG45233.1 - 0.12 12.5 14.0 0.33 11.0 7.4 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DIT1_PvcA PF05141.12 CEG45233.1 - 0.15 11.5 5.7 0.16 11.4 5.7 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Borrelia_P83 PF05262.11 CEG45233.1 - 0.39 9.1 11.5 0.4 9.1 11.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein vATP-synt_E PF01991.18 CEG45233.1 - 0.49 9.8 11.0 0.27 10.6 5.1 2.0 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF4168 PF13767.6 CEG45233.1 - 2.3 9.5 11.6 14 7.0 11.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) CENP-H PF05837.12 CEG45233.1 - 8.6 6.8 11.3 14 6.1 11.3 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) HTH_23 PF13384.6 CEG45234.1 - 0.045 13.6 0.6 0.065 13.0 0.6 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEG45234.1 - 0.092 12.8 0.1 0.25 11.5 0.1 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 CEG45234.1 - 0.2 11.8 0.2 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Claudin_3 PF06653.11 CEG45235.1 - 0.1 12.5 9.8 0.32 10.9 3.9 2.4 1 1 0 2 2 2 0 Tight junction protein, Claudin-like DUF2723 PF11028.8 CEG45235.1 - 3.3 7.6 6.6 0.35 10.8 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Exo_endo_phos PF03372.23 CEG45237.1 - 2.2e-09 37.2 0.0 6.6e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DSPc PF00782.20 CEG45243.1 - 1.9e-28 98.9 0.0 2.4e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG45243.1 - 0.0032 17.1 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CEG45243.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CEG45243.1 - 0.038 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CEG45243.1 - 0.068 12.7 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Acyl_transf_3 PF01757.22 CEG45244.1 - 6.5e-13 48.4 32.3 8.9e-13 48.0 32.3 1.2 1 0 0 1 1 1 1 Acyltransferase family CHS5_N PF16892.5 CEG45244.1 - 0.009 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus Sep15_SelM PF08806.11 CEG45245.1 - 4e-20 71.7 0.3 6.7e-20 71.0 0.3 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain PolyA_pol PF01743.20 CEG45247.1 - 6.3e-24 84.8 0.2 1.7e-23 83.4 0.2 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CEG45247.1 - 3e-08 33.3 0.2 9e-08 31.8 0.2 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Peptidase_S8 PF00082.22 CEG45248.1 - 3.9e-43 147.8 8.0 9.1e-43 146.6 8.0 1.7 1 0 0 1 1 1 1 Subtilase family Herpes_gE PF02480.16 CEG45248.1 - 0.0036 16.1 0.0 0.0066 15.2 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RRM_7 PF16367.5 CEG45249.1 - 2.9e-05 24.1 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif DUF4748 PF15932.5 CEG45249.1 - 0.0066 16.2 1.4 0.03 14.1 1.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) RRM_1 PF00076.22 CEG45249.1 - 0.039 13.8 0.1 0.31 10.9 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2972 PF11186.8 CEG45249.1 - 0.81 9.6 6.7 0.57 10.1 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) TPR_1 PF00515.28 CEG45250.1 - 1.4e-23 81.7 30.0 4.6e-06 26.2 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEG45250.1 - 3e-20 70.6 36.3 9.5e-07 28.5 0.0 10.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEG45250.1 - 1.7e-18 66.0 6.5 6.1e-07 29.0 0.1 7.0 4 2 3 7 7 7 4 TPR repeat TPR_17 PF13431.6 CEG45250.1 - 4.9e-14 51.6 6.3 0.00092 19.4 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG45250.1 - 5.7e-11 42.4 32.2 7.5e-06 26.0 0.8 8.4 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45250.1 - 2.6e-10 40.7 31.2 6.7e-08 32.9 0.7 7.8 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45250.1 - 3.2e-10 39.4 30.9 0.024 14.8 0.0 10.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45250.1 - 3.2e-06 27.3 0.9 0.0012 19.1 0.5 8.7 7 2 2 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEG45250.1 - 7.7e-06 26.5 1.3 7.7e-06 26.5 1.3 6.7 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45250.1 - 3.2e-05 24.4 50.4 6.4e-05 23.4 0.4 11.3 10 2 1 11 11 10 3 Tetratricopeptide repeat NTP_transf_2 PF01909.23 CEG45250.1 - 0.0014 18.8 0.0 0.0053 17.0 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_20 PF14561.6 CEG45250.1 - 0.003 17.8 0.1 0.003 17.8 0.1 5.0 4 2 1 5 5 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CEG45250.1 - 0.006 16.0 10.2 3.1 7.3 0.0 6.4 7 0 0 7 7 7 1 SHNi-TPR ANAPC3 PF12895.7 CEG45250.1 - 0.022 15.0 10.5 1.2 9.4 0.4 4.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Paf67 PF10255.9 CEG45250.1 - 0.052 12.5 1.9 0.098 11.6 0.1 2.3 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 RPN7 PF10602.9 CEG45250.1 - 0.17 11.6 0.1 0.17 11.6 0.1 4.7 4 1 1 5 5 5 0 26S proteasome subunit RPN7 SRP_TPR_like PF17004.5 CEG45250.1 - 2.3 8.3 5.5 0.6 10.1 0.1 2.8 3 1 0 3 3 3 0 Putative TPR-like repeat Ribosomal_L21p PF00829.21 CEG45251.1 - 2.3e-28 98.4 2.7 6.2e-28 97.0 2.7 1.7 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein NAC PF01849.18 CEG45251.1 - 5e-21 74.4 2.6 5e-21 74.4 2.6 2.3 3 0 0 3 3 3 1 NAC domain PGA2 PF07543.12 CEG45251.1 - 2.8 7.9 7.3 10 6.1 1.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Zip PF02535.22 CEG45253.1 - 1.1e-62 212.2 17.7 1.8e-60 204.9 9.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter CoA_binding_3 PF13727.6 CEG45253.1 - 0.066 13.2 0.3 7.5 6.5 0.0 2.4 2 0 0 2 2 2 0 CoA-binding domain CbtA PF09490.10 CEG45253.1 - 5.1 6.8 15.3 0.048 13.4 1.2 2.8 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtA) T2SS-T3SS_pil_N PF13629.6 CEG45255.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pilus formation protein N terminal region RVT_2 PF07727.14 CEG45257.1 - 4.4e-24 85.4 1.1 4.8e-24 85.3 1.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG45257.1 - 0.018 14.5 0.3 0.023 14.2 0.3 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sas6_CC PF18594.1 CEG45257.1 - 0.059 13.2 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain GH131_N PF18271.1 CEG45259.1 - 3.4e-57 194.1 2.3 3.9e-57 193.9 2.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG45259.1 - 0.00014 21.8 0.3 0.0002 21.3 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide lyase GH131_N PF18271.1 CEG45260.1 - 4.2e-50 170.8 0.0 4.8e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG45260.1 - 0.0039 17.1 0.1 0.0099 15.7 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide lyase SQHop_cyclase_C PF13243.6 CEG45260.1 - 0.051 12.7 0.1 0.078 12.1 0.1 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain LRR_8 PF13855.6 CEG45262.1 - 1.3e-06 28.1 2.7 0.17 11.7 0.1 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEG45262.1 - 0.00027 21.3 0.2 2.5 8.7 0.0 4.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LMF1 PF06762.14 CEG45262.1 - 1.1 8.2 4.9 0.19 10.8 1.2 1.5 2 0 0 2 2 2 0 Lipase maturation factor Bax1-I PF01027.20 CEG45268.1 - 5.6e-27 94.9 22.4 6.7e-27 94.7 22.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 AAA PF00004.29 CEG45269.1 - 3.3e-97 322.0 0.0 1.6e-47 161.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG45269.1 - 1.7e-23 82.1 8.5 6.7e-12 45.0 0.7 2.9 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CEG45269.1 - 1.4e-20 73.3 3.0 1.8e-20 72.9 1.6 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 CEG45269.1 - 3.6e-14 52.3 0.0 8e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 CEG45269.1 - 6.6e-14 52.0 0.0 7.9e-06 25.7 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEG45269.1 - 4.4e-13 49.7 0.0 4.3e-06 26.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEG45269.1 - 1.4e-12 48.3 3.2 0.00018 22.0 0.1 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 CEG45269.1 - 3.2e-12 46.8 0.1 7.7e-06 26.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CEG45269.1 - 4.3e-11 43.0 0.1 8.1e-06 25.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG45269.1 - 1.9e-10 41.1 0.7 0.021 15.1 0.1 4.9 3 2 2 5 5 5 2 AAA domain TIP49 PF06068.13 CEG45269.1 - 1.8e-08 34.0 0.0 0.00076 18.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CEG45269.1 - 8.4e-08 32.3 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG45269.1 - 3.6e-07 30.8 0.0 0.038 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CEG45269.1 - 5.6e-07 29.5 0.2 8.8e-06 25.6 0.0 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 CEG45269.1 - 6.9e-07 28.9 0.1 0.043 13.2 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CEG45269.1 - 7.4e-07 29.5 0.0 0.014 15.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_25 PF13481.6 CEG45269.1 - 4.8e-06 26.3 0.3 2.1 7.9 0.0 3.5 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CEG45269.1 - 6.2e-06 26.1 0.1 0.13 12.0 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CEG45269.1 - 8.3e-06 25.3 0.1 2.2 7.5 0.0 3.5 3 0 0 3 3 3 2 KaiC ATPase_2 PF01637.18 CEG45269.1 - 9.2e-06 25.7 0.1 0.19 11.6 0.0 3.0 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CEG45269.1 - 1.2e-05 25.2 0.0 0.0061 16.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 CEG45269.1 - 1.5e-05 25.0 0.0 0.057 13.2 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_17 PF13207.6 CEG45269.1 - 1.7e-05 25.3 0.0 0.11 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CEG45269.1 - 2.4e-05 24.0 0.0 0.15 11.5 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 CEG45269.1 - 3.3e-05 24.4 0.0 0.17 12.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 CEG45269.1 - 4.5e-05 23.8 0.4 0.33 11.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 CEG45269.1 - 7.1e-05 22.8 0.0 0.83 9.6 0.0 3.6 3 1 1 4 4 4 2 NACHT domain Zeta_toxin PF06414.12 CEG45269.1 - 8.5e-05 21.9 0.0 0.58 9.4 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_24 PF13479.6 CEG45269.1 - 0.00011 22.0 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEG45269.1 - 0.00011 21.9 0.0 0.58 9.8 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 CEG45269.1 - 0.00013 22.0 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CEG45269.1 - 0.00018 20.7 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CEG45269.1 - 0.00022 20.5 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 CEG45269.1 - 0.00079 19.6 0.0 0.42 10.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 CEG45269.1 - 0.00088 19.4 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF815 PF05673.13 CEG45269.1 - 0.0012 18.1 0.0 0.37 9.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 CEG45269.1 - 0.0014 18.5 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CEG45269.1 - 0.0018 18.3 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CEG45269.1 - 0.0043 16.3 0.0 0.95 8.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CEG45269.1 - 0.005 16.8 0.7 4.5 7.2 0.0 3.9 3 1 1 4 4 4 0 NTPase AAA_19 PF13245.6 CEG45269.1 - 0.0086 16.4 0.2 8.7 6.7 0.1 3.3 2 1 0 3 3 2 0 AAA domain Rad17 PF03215.15 CEG45269.1 - 0.0092 15.9 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 CEG45269.1 - 0.012 15.4 0.2 5.9 6.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CEG45269.1 - 0.014 14.8 4.1 1.8 7.9 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein SKI PF01202.22 CEG45269.1 - 0.021 14.9 0.1 9.1 6.4 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CEG45269.1 - 0.033 13.9 0.0 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 CEG45269.1 - 0.034 13.8 0.5 6.4 6.4 0.1 2.9 3 0 0 3 3 2 0 AAA domain Zot PF05707.12 CEG45269.1 - 0.059 13.0 0.0 1.3 8.6 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_29 PF13555.6 CEG45269.1 - 0.077 12.7 0.0 6.7 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 CEG45269.1 - 0.092 12.1 0.0 13 5.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein KAP_NTPase PF07693.14 CEG45269.1 - 0.099 11.9 0.1 2.7 7.1 0.0 2.9 2 2 1 4 4 4 0 KAP family P-loop domain PduV-EutP PF10662.9 CEG45269.1 - 0.19 11.5 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.25 CEG45270.1 - 3.2e-65 220.1 0.0 4.2e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45270.1 - 4.8e-28 98.2 0.0 9.2e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45270.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG45270.1 - 0.00019 20.8 0.1 0.00047 19.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG45270.1 - 0.0047 15.9 0.3 0.01 14.8 0.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG45270.1 - 0.016 14.0 0.0 0.036 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CEG45270.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 CEG45270.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dus PF01207.17 CEG45271.1 - 1.3e-50 172.3 0.0 3.4e-50 170.9 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 CEG45271.1 - 5.4e-07 29.7 1.0 5.4e-07 29.7 1.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG45271.1 - 2.9e-05 24.3 0.7 8.4e-05 22.8 0.7 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEG45271.1 - 0.0014 18.9 1.5 0.0036 17.6 1.5 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) IGPS PF00218.21 CEG45271.1 - 0.0062 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase RimK PF08443.11 CEG45271.1 - 0.02 14.5 0.7 0.042 13.5 0.7 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain AKAP95 PF04988.12 CEG45271.1 - 0.024 14.9 0.3 0.052 13.8 0.3 1.6 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) PA28_alpha PF02251.18 CEG45271.1 - 0.036 14.1 0.1 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit zf-U1 PF06220.12 CEG45271.1 - 0.045 13.5 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger PrmA PF06325.13 CEG45271.1 - 0.053 12.9 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PLAC8 PF04749.17 CEG45272.1 - 1.1e-07 32.7 2.6 1.5e-07 32.3 2.6 1.2 1 0 0 1 1 1 1 PLAC8 family DUF2116 PF09889.9 CEG45273.1 - 0.23 11.5 0.5 0.46 10.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FYVE PF01363.21 CEG45274.1 - 0.0017 18.5 14.6 0.0035 17.4 14.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 CEG45274.1 - 0.013 15.8 8.0 0.031 14.6 8.0 1.6 1 0 0 1 1 1 0 C1 domain zf-HC5HC2H PF13771.6 CEG45274.1 - 0.94 9.8 10.4 2.4 8.5 10.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain WD40 PF00400.32 CEG45276.1 - 7e-06 26.7 7.1 19 6.3 0.2 6.9 6 0 0 6 6 6 2 WD domain, G-beta repeat SLIDE PF09111.10 CEG45276.1 - 0.019 15.0 0.3 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 SLIDE EF-hand_7 PF13499.6 CEG45276.1 - 0.025 15.0 0.0 0.09 13.2 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 CEG45276.1 - 0.026 14.1 0.6 0.094 12.3 0.6 2.0 1 0 0 1 1 1 0 EF hand PspA_IM30 PF04012.12 CEG45276.1 - 0.034 13.7 6.0 0.25 10.9 0.3 2.5 2 0 0 2 2 2 0 PspA/IM30 family Glycos_transf_1 PF00534.20 CEG45277.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Herpes_DNAp_acc PF04929.12 CEG45277.1 - 0.032 13.2 0.1 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Amino_oxidase PF01593.24 CEG45281.1 - 7.8e-45 154.0 0.0 9.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAR1 PF03101.15 CEG45282.1 - 0.012 16.3 0.1 0.021 15.5 0.1 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain AFT PF08731.11 CEG45282.1 - 0.031 14.7 0.1 0.26 11.7 0.0 1.9 1 1 1 2 2 2 0 Transcription factor AFT Pkinase PF00069.25 CEG45283.1 - 2.5e-46 158.2 0.0 3.2e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45283.1 - 8.8e-30 103.8 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45283.1 - 3.9e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG45283.1 - 0.0051 15.6 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CEG45283.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family MTHFR PF02219.17 CEG45284.1 - 3.2e-117 390.9 0.0 4.7e-117 390.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase WD40 PF00400.32 CEG45285.1 - 1e-40 137.0 17.2 1.5e-08 35.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG45285.1 - 9.1e-09 35.5 0.1 0.045 14.1 0.0 5.6 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG45285.1 - 2.2e-07 30.5 0.3 0.0003 20.2 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 CEG45285.1 - 5e-05 23.3 0.0 0.19 11.6 0.0 3.4 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 CEG45285.1 - 0.0017 18.2 0.1 5.2 7.2 0.1 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat BBS2_Mid PF14783.6 CEG45285.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.9 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 CEG45285.1 - 0.014 13.8 0.0 0.088 11.1 0.0 2.1 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz SARS_X4 PF08779.10 CEG45285.1 - 0.067 13.4 0.2 0.63 10.3 0.0 2.6 2 2 0 2 2 2 0 SARS coronavirus X4 like Rtf2 PF04641.12 CEG45286.1 - 2.4e-59 200.9 15.2 2.8e-59 200.6 15.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 CEG45286.1 - 0.095 12.5 2.1 0.6 10.0 0.4 2.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit GCD14 PF08704.10 CEG45286.1 - 0.25 11.0 2.9 0.44 10.2 2.9 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Vps39_2 PF10367.9 CEG45286.1 - 0.7 10.4 9.2 4.4 7.8 0.2 3.1 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 TGase_elicitor PF16683.5 CEG45287.1 - 9.5e-28 97.0 0.0 1e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor GCN5L1 PF06320.13 CEG45291.1 - 0.3 11.3 6.5 0.082 13.1 1.8 2.0 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) BING4CT PF08149.11 CEG45292.1 - 1e-40 137.4 0.0 2e-37 126.8 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 CEG45292.1 - 1.3e-05 25.8 0.0 0.19 12.7 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG45292.1 - 0.002 18.4 0.0 5.7 7.3 0.0 4.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3987 PF13148.6 CEG45292.1 - 2.5 7.0 8.3 4.9 6.1 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YABBY PF04690.13 CEG45292.1 - 3 8.4 5.3 5.9 7.4 5.3 1.5 1 0 0 1 1 1 0 YABBY protein Cullin PF00888.22 CEG45293.1 - 1.9e-154 515.6 5.0 1.2e-132 443.6 1.7 2.2 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 CEG45293.1 - 2.9e-24 84.9 2.0 2.9e-24 84.9 2.0 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain FHA PF00498.26 CEG45294.1 - 2.9e-12 46.8 0.0 5.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 CEG45294.1 - 1.2e-09 37.8 8.2 2.6e-09 36.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG45294.1 - 1.3e-09 37.7 7.6 3.2e-09 36.5 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG45294.1 - 5.8e-09 36.2 9.3 1.5e-08 34.8 9.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEG45294.1 - 1.9e-08 34.3 11.4 4e-08 33.3 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG45294.1 - 4.8e-08 32.7 4.8 9.6e-08 31.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG45294.1 - 5.4e-08 32.7 7.5 1.6e-07 31.2 7.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG45294.1 - 0.00083 19.3 6.2 0.0022 17.9 6.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEG45294.1 - 0.00084 19.2 8.6 0.0043 16.9 8.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG45294.1 - 0.0044 17.3 8.9 0.017 15.4 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CEG45294.1 - 0.014 15.2 5.2 0.033 14.1 3.4 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Colicin_Ia PF11504.8 CEG45294.1 - 0.026 14.6 0.2 2.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Colicin Ia Baculo_LEF5_C PF11792.8 CEG45294.1 - 0.077 12.7 0.1 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-RING_10 PF16685.5 CEG45294.1 - 0.15 12.2 2.8 0.89 9.7 2.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CEG45294.1 - 0.19 11.5 4.9 0.56 10.0 4.9 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-MYST PF17772.1 CEG45294.1 - 0.27 10.9 1.3 0.49 10.0 0.4 1.9 2 0 0 2 2 2 0 MYST family zinc finger domain DUF4451 PF14616.6 CEG45294.1 - 0.63 10.3 2.8 5.7 7.2 1.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) E_raikovi_mat PF06360.11 CEG45294.1 - 6 7.4 5.9 4.9 7.7 0.7 2.7 3 0 0 3 3 2 0 Euplotes raikovi mating pheromone zf-RING_4 PF14570.6 CEG45294.1 - 6.1 6.7 7.5 28 4.6 7.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TTL PF03133.15 CEG45296.1 - 3.4e-84 282.5 1.1 5e-84 281.9 1.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CS PF04969.16 CEG45296.1 - 2.4e-12 47.7 0.1 6.1e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 CS domain ATPgrasp_YheCD PF14398.6 CEG45296.1 - 6.5e-08 32.1 0.2 5e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CEG45296.1 - 0.00028 20.2 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 CEG45296.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DDE_1 PF03184.19 CEG45298.1 - 0.0076 15.9 0.0 0.0092 15.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 CEG45299.1 - 2e-67 227.3 0.0 3.2e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45299.1 - 7.6e-36 123.7 0.0 1.4e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DAGK_cat PF00781.24 CEG45299.1 - 8.9e-25 86.7 0.0 2.1e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FYVE PF01363.21 CEG45299.1 - 7.4e-12 45.2 12.4 1.6e-11 44.1 12.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arb2 PF09757.9 CEG45299.1 - 6.8e-07 28.7 0.0 2.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Arb2 domain Pkinase_C PF00433.24 CEG45299.1 - 1e-05 26.1 0.0 4.9e-05 23.9 0.0 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain FYVE_2 PF02318.16 CEG45299.1 - 5e-05 23.5 6.5 5e-05 23.5 6.5 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Haspin_kinase PF12330.8 CEG45299.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Siva PF05458.12 CEG45299.1 - 0.24 11.1 4.1 2.9 7.6 2.7 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Prok-RING_2 PF14445.6 CEG45299.1 - 2 8.6 5.5 7.8 6.8 5.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 zf-B_box PF00643.24 CEG45301.1 - 1.2e-05 25.3 3.4 2.7e-05 24.2 3.4 1.6 1 0 0 1 1 1 1 B-box zinc finger C1_2 PF03107.16 CEG45301.1 - 2.1 8.8 7.1 5.6 7.4 7.1 1.8 1 0 0 1 1 1 0 C1 domain zf-RING_4 PF14570.6 CEG45302.1 - 1.3e-20 72.9 12.0 2.3e-20 72.1 12.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CEG45302.1 - 3.2e-07 30.1 10.4 5.5e-07 29.4 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CEG45302.1 - 6.1e-05 22.8 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 CEG45302.1 - 0.0038 17.5 13.7 0.0076 16.6 13.7 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CEG45302.1 - 0.0051 16.2 2.5 0.011 15.2 2.5 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger CBP4 PF07960.11 CEG45302.1 - 0.033 14.0 0.4 0.073 12.9 0.4 1.5 1 0 0 1 1 1 0 CBP4 zf-UDP PF14569.6 CEG45302.1 - 0.053 13.6 7.6 0.02 15.0 5.0 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 CEG45302.1 - 0.073 12.9 11.3 0.55 10.1 9.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CEG45302.1 - 0.25 11.3 7.2 0.61 10.0 4.1 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-CCCH_2 PF14608.6 CEG45302.1 - 0.52 10.9 3.3 1.5 9.4 3.3 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Aldose_epim PF01263.20 CEG45303.1 - 8.9e-32 110.6 0.1 1.4e-31 109.9 0.1 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase DUF4807 PF16065.5 CEG45304.1 - 8.4e-10 38.4 0.1 2.3e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4807) PHTB1_N PF14727.6 CEG45305.1 - 1.6e-133 446.1 0.0 2.3e-133 445.6 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 CEG45305.1 - 6.8e-132 440.1 1.2 8.9e-132 439.7 1.2 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus Peptidase_S10 PF00450.22 CEG45306.1 - 3.6e-120 402.2 0.0 4.1e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-CCHC PF00098.23 CEG45307.1 - 0.0048 16.9 0.5 0.01 15.9 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle TPR_12 PF13424.6 CEG45311.1 - 8e-07 29.3 17.7 0.0019 18.5 8.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG45311.1 - 0.0021 17.8 5.1 0.59 10.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat GAPT PF11770.8 CEG45311.1 - 0.014 15.2 0.4 2.5 8.0 0.0 2.8 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) TPR_2 PF07719.17 CEG45311.1 - 0.033 14.3 14.7 0.12 12.5 2.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PriA_CRR PF18319.1 CEG45311.1 - 0.067 13.2 0.9 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Endosulfine PF04667.17 CEG45312.1 - 4.2e-30 103.7 10.7 9.3e-11 41.7 0.0 5.4 5 1 0 5 5 5 4 cAMP-regulated phosphoprotein/endosulfine conserved region DUF190 PF02641.15 CEG45312.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 DUF3280 PF11684.8 CEG45312.1 - 1.2 9.5 5.7 6.4 7.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2380) EF-hand_1 PF00036.32 CEG45313.1 - 7.6e-42 137.8 14.2 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG45313.1 - 1e-35 122.0 3.4 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEG45313.1 - 1.6e-32 111.1 12.1 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CEG45313.1 - 2.2e-30 101.9 7.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEG45313.1 - 8.7e-27 91.4 10.5 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEG45313.1 - 2.2e-16 59.9 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEG45313.1 - 7.2e-10 38.8 0.8 0.00014 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG45313.1 - 2e-08 34.5 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CEG45313.1 - 4.2e-07 30.8 0.0 0.00016 22.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CEG45313.1 - 8.7e-06 25.7 0.9 0.042 13.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CEG45313.1 - 6.4e-05 23.0 1.0 0.00037 20.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CEG45313.1 - 0.00027 21.0 3.9 0.045 13.9 0.3 2.8 1 1 0 2 2 2 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 CEG45313.1 - 0.0013 19.0 0.4 0.73 10.2 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 CEG45313.1 - 0.0017 18.3 0.3 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.11 CEG45313.1 - 0.0019 17.9 2.1 0.0022 17.7 2.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 CEG45313.1 - 0.0019 18.9 0.4 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CEG45313.1 - 0.0024 17.8 1.4 0.49 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 CEG45313.1 - 0.0074 14.9 0.0 0.0074 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 CEG45313.1 - 0.022 13.4 0.1 0.6 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 CEG45313.1 - 0.028 14.6 0.1 4.1 7.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 CEG45313.1 - 0.029 14.2 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 CEG45313.1 - 0.035 14.2 0.4 0.54 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 CEG45313.1 - 0.047 12.9 0.1 3.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CEG45313.1 - 0.061 13.0 1.0 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 CEG45313.1 - 0.075 13.4 0.2 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 CEG45313.1 - 0.27 11.3 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 LRR_8 PF13855.6 CEG45317.1 - 4.6e-26 90.4 56.2 9.3e-10 38.1 3.3 5.0 1 1 6 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 CEG45317.1 - 4e-16 58.9 30.5 3.5e-06 27.3 0.9 5.8 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG45317.1 - 2.6e-08 33.3 16.6 6.1 7.8 1.3 8.4 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 CEG45317.1 - 0.00095 19.0 27.3 0.17 12.0 0.0 7.8 9 0 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.6 CEG45317.1 - 0.018 14.6 11.3 0.37 10.3 0.6 2.5 1 1 1 2 2 2 0 Leucine-rich repeat RsmF_methylt_CI PF17126.5 CEG45317.1 - 0.066 13.3 0.7 14 5.9 0.0 3.6 2 2 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Methyltrn_RNA_3 PF02598.17 CEG45318.1 - 1.8e-106 355.8 0.0 2.6e-106 355.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase NOG1_N PF17835.1 CEG45318.1 - 0.036 14.0 1.6 0.072 13.1 1.6 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain PHD PF00628.29 CEG45319.1 - 2.8e-06 27.1 7.3 2.8e-06 27.1 7.3 3.2 2 1 1 3 3 3 1 PHD-finger zf-RING_6 PF14835.6 CEG45319.1 - 0.2 11.5 11.0 0.84 9.6 11.0 2.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Guanylate_cyc PF00211.20 CEG45320.1 - 1.9e-09 37.4 0.0 9.2e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Tubulin_3 PF14881.6 CEG45324.1 - 1.9e-08 34.2 0.0 4.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Myotub-related PF06602.14 CEG45325.1 - 6.3e-124 413.5 0.0 1e-123 412.8 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain STIMATE PF12400.8 CEG45325.1 - 2.6e-35 121.7 6.3 4.8e-35 120.8 6.3 1.5 1 0 0 1 1 1 1 STIMATE family GRAM PF02893.20 CEG45325.1 - 1.3e-06 28.2 0.2 6.5e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 GRAM domain Cnn_1N PF07989.11 CEG45325.1 - 0.016 15.4 3.3 0.04 14.1 3.3 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Y_phosphatase3 PF13350.6 CEG45325.1 - 0.082 12.9 0.4 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family CCDC106 PF15794.5 CEG45325.1 - 0.53 10.0 5.0 0.074 12.7 0.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DivIC PF04977.15 CEG45325.1 - 3.3 7.6 6.5 8.1 6.3 6.5 1.6 1 0 0 1 1 1 0 Septum formation initiator Myosin_head PF00063.21 CEG45326.1 - 2.3e-225 749.9 5.5 3.3e-225 749.4 5.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) CBS PF00571.28 CEG45326.1 - 1e-121 397.4 57.1 3.5e-08 33.8 0.1 22.2 22 0 0 22 22 22 16 CBS domain PB1 PF00564.24 CEG45326.1 - 3e-09 36.7 0.0 1.2e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 PB1 domain IQ PF00612.27 CEG45326.1 - 0.0017 17.9 5.7 0.57 10.1 0.0 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_16 PF13191.6 CEG45326.1 - 0.016 15.6 0.0 0.2 12.0 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEG45326.1 - 0.019 15.2 0.1 2.6 8.3 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF4388 PF14332.6 CEG45326.1 - 0.049 13.9 0.0 14 6.0 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4388) CbiA PF01656.23 CEG45326.1 - 0.085 12.9 0.3 0.66 10.0 0.0 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran_CTD PF16326.5 CEG45326.1 - 0.23 11.7 23.1 0.27 11.5 1.0 5.1 2 1 2 4 4 4 0 ABC transporter C-terminal domain RNA_helicase PF00910.22 CEG45326.1 - 0.35 11.3 3.1 4.7 7.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase DUF1192 PF06698.11 CEG45326.1 - 0.41 10.7 3.9 1.4 9.0 0.9 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) BST2 PF16716.5 CEG45326.1 - 1.4 9.6 11.1 4.1 8.0 1.1 3.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4808 PF16066.5 CEG45326.1 - 3.4 8.2 10.3 40 4.8 3.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4808) LUC7 PF03194.15 CEG45326.1 - 6.4 6.4 14.7 6.3 6.4 1.0 2.7 1 1 1 2 2 2 0 LUC7 N_terminus Cep57_CLD PF14073.6 CEG45327.1 - 0.0022 18.0 33.0 0.0022 18.0 33.0 2.9 2 1 1 3 3 3 1 Centrosome localisation domain of Cep57 NPV_P10 PF05531.12 CEG45327.1 - 1.8 9.1 12.6 2.6 8.6 0.2 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-S PF15630.6 CEG45328.1 - 3e-21 75.6 0.4 5.8e-21 74.7 0.4 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEG45328.1 - 1.4e-10 41.3 1.3 1.8e-10 40.9 0.8 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 CEG45328.1 - 0.0038 17.2 0.5 0.0068 16.4 0.3 1.6 2 1 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 CEG45328.1 - 0.019 15.2 1.7 0.024 14.9 0.5 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CEG45328.1 - 0.14 12.3 1.2 0.23 11.7 0.3 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) BROMI PF14961.6 CEG45329.1 - 1.3e-19 69.3 3.2 1.3e-19 69.3 3.2 2.8 2 1 0 2 2 2 1 Broad-minded protein SelK_SelG PF10961.8 CEG45329.1 - 0.17 12.5 0.5 47 4.7 0.1 3.0 3 0 0 3 3 3 0 Selenoprotein SelK_SelG PapD-like PF14874.6 CEG45331.1 - 2.6e-06 27.5 0.1 5.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Adap_comp_sub PF00928.21 CEG45332.1 - 5.8e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family GCK PF07802.11 CEG45333.1 - 0.003 17.9 3.0 0.03 14.7 0.7 2.2 2 0 0 2 2 2 1 GCK domain CX9C PF16860.5 CEG45333.1 - 0.039 14.0 1.3 0.11 12.6 1.1 2.0 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 CEG45333.1 - 0.078 13.2 4.3 0.074 13.3 2.0 1.9 1 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 CEG45333.1 - 0.74 9.9 5.2 3.3 7.8 1.8 2.8 3 1 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M14 PF00246.24 CEG45337.1 - 1.2e-16 61.3 0.3 3e-16 60.1 0.3 1.6 1 0 0 1 1 1 1 Zinc carboxypeptidase BUD22 PF09073.10 CEG45337.1 - 0.0028 17.1 9.1 0.0039 16.6 9.1 1.2 1 0 0 1 1 1 1 BUD22 MSC PF09402.10 CEG45337.1 - 0.01 15.3 1.0 0.019 14.5 1.0 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain AstE_AspA PF04952.14 CEG45337.1 - 0.036 13.1 1.0 1.8 7.6 1.0 2.2 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family KCT2 PF17818.1 CEG45337.1 - 0.065 13.4 3.6 0.16 12.1 3.6 1.6 1 0 0 1 1 1 0 Keratinocyte-associated gene product Orf78 PF06024.12 CEG45337.1 - 0.18 12.1 3.8 0.13 12.5 0.3 2.4 1 1 1 2 2 2 0 Orf78 (ac78) TFIIF_alpha PF05793.12 CEG45337.1 - 2.7 6.5 15.5 4.9 5.6 15.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CBF PF03914.17 CEG45339.1 - 1.3e-29 103.5 1.5 1.3e-29 103.5 1.5 2.5 3 0 0 3 3 3 1 CBF/Mak21 family PRP38_assoc PF12871.7 CEG45339.1 - 0.076 13.6 1.0 0.19 12.3 1.0 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term V-ATPase_H_C PF11698.8 CEG45339.1 - 0.35 11.0 3.9 16 5.6 0.9 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Rotamase PF00639.21 CEG45340.1 - 1.8e-20 73.7 0.1 8.4e-20 71.5 0.1 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CEG45340.1 - 2.1e-17 63.7 0.1 4.3e-16 59.5 0.1 2.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CEG45340.1 - 3e-06 28.1 0.0 5.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CEG45340.1 - 0.002 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 WW domain X8 PF07983.13 CEG45340.1 - 0.03 15.0 0.0 0.046 14.4 0.0 1.3 1 0 0 1 1 1 0 X8 domain ThiD2 PF17792.1 CEG45340.1 - 0.57 10.7 4.1 2 8.9 4.1 1.8 1 1 0 1 1 1 0 ThiD2 family Dimer_Tnp_hAT PF05699.14 CEG45342.1 - 6.7e-12 45.0 0.1 1.2e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TRAF_BIRC3_bd PF16673.5 CEG45343.1 - 0.098 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain PRP21_like_P PF12230.8 CEG45345.1 - 0.018 14.9 2.8 0.021 14.7 2.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein AhpC-TSA PF00578.21 CEG45346.1 - 1.3e-38 131.7 0.0 2.9e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 CEG45346.1 - 6.6e-20 71.0 0.1 1.2e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CEG45346.1 - 8.5e-16 58.0 0.0 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.9 CEG45346.1 - 3.3e-13 49.2 0.1 7.1e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_2 PF13098.6 CEG45346.1 - 5e-05 23.7 0.3 0.00042 20.7 0.2 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG45346.1 - 0.00018 21.8 0.0 0.021 15.1 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEG45346.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEG45346.1 - 0.022 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like RRM_1 PF00076.22 CEG45347.1 - 3.8e-28 97.1 0.1 1.7e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 CEG45347.1 - 8.4e-12 44.8 8.9 1.6e-11 43.9 8.9 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 CEG45347.1 - 5.9e-08 31.9 4.5 1.2e-07 30.9 4.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 CEG45347.1 - 1.5e-06 28.2 3.2 4.8e-06 26.6 3.2 1.9 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 CEG45347.1 - 0.00013 21.9 8.4 0.0004 20.3 8.1 1.9 2 0 0 2 2 2 1 OCRE domain PHM7_cyt PF14703.6 CEG45347.1 - 0.00027 21.2 0.3 0.71 10.1 0.0 3.3 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter DUF4523 PF15023.6 CEG45347.1 - 0.027 14.3 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) zf-C2H2_11 PF16622.5 CEG45347.1 - 0.036 13.8 0.5 0.079 12.7 0.5 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CEG45347.1 - 0.1 12.9 0.3 0.27 11.6 0.3 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEG45347.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG45348.1 - 1.8e-07 31.3 1.6 4.3e-07 30.1 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEG45348.1 - 6.6e-07 29.5 0.7 1.2e-06 28.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 CEG45348.1 - 0.002 18.2 1.9 0.0077 16.3 1.9 2.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 CEG45348.1 - 0.003 17.3 1.4 0.0063 16.3 1.4 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-DBF PF07535.12 CEG45348.1 - 0.12 12.5 1.6 0.26 11.4 1.6 1.6 1 0 0 1 1 1 0 DBF zinc finger Stathmin PF00836.19 CEG45348.1 - 3.1 7.8 18.9 3 7.8 13.0 2.7 2 1 1 3 3 3 0 Stathmin family Ferlin_C PF16165.5 CEG45348.1 - 5.5 6.9 6.5 1.5 8.8 3.1 1.7 2 0 0 2 2 2 0 Ferlin C-terminus FYVE PF01363.21 CEG45349.1 - 2.1e-13 50.2 9.4 2.1e-13 50.2 9.4 2.1 2 0 0 2 2 2 1 FYVE zinc finger Ank_5 PF13857.6 CEG45349.1 - 1.5e-08 34.7 0.0 1.3e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Thaumatin PF00314.17 CEG45350.1 - 0.0034 17.0 3.4 0.37 10.4 1.4 2.9 2 1 1 3 3 3 2 Thaumatin family NDUF_B12 PF08122.12 CEG45350.1 - 0.004 17.1 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family Kinesin PF00225.23 CEG45351.1 - 9.4e-112 373.2 0.7 1.7e-111 372.3 0.7 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG45351.1 - 3.2e-25 88.8 0.9 1.3e-24 86.9 0.1 2.2 2 0 0 2 2 2 1 Microtubule binding Pkinase PF00069.25 CEG45352.1 - 3.1e-51 174.3 0.0 3e-46 157.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45352.1 - 2e-16 60.0 0.0 7e-14 51.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG45352.1 - 0.012 15.0 0.0 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CEG45352.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFB6 PF17110.5 CEG45352.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Choline_kinase PF01633.20 CEG45352.1 - 0.18 11.4 0.1 0.52 9.9 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Thioredoxin_8 PF13905.6 CEG45353.1 - 1.4e-14 54.2 0.0 1.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CEG45353.1 - 0.14 12.2 0.0 10 6.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Rootletin PF15035.6 CEG45354.1 - 0.00056 20.0 1.4 0.0007 19.7 0.6 1.5 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion MRC1 PF09444.10 CEG45354.1 - 8.5 6.9 12.6 50 4.4 12.6 2.1 1 1 0 1 1 1 0 MRC1-like domain EamA PF00892.20 CEG45357.1 - 4.8e-18 65.7 41.5 5.6e-11 42.8 20.1 3.1 2 1 1 3 3 3 3 EamA-like transporter family adh_short PF00106.25 CEG45361.1 - 1.8e-43 148.3 0.9 2.3e-43 147.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG45361.1 - 1.7e-34 119.4 1.3 6.6e-34 117.5 1.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG45361.1 - 2.5e-13 50.4 0.6 7.7e-13 48.7 0.6 1.7 1 1 0 1 1 1 1 KR domain Complex1_LYR PF05347.15 CEG45363.1 - 9.4e-09 35.2 1.5 1.4e-08 34.7 1.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) eIF-1a PF01176.19 CEG45363.1 - 0.0026 17.5 0.1 0.0032 17.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 cobW PF02492.19 CEG45364.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MgpC PF05220.12 CEG45366.1 - 0.0019 17.6 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 MgpC protein precursor CHASE3 PF05227.13 CEG45366.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 CHASE3 domain Heme_oxygenase PF01126.20 CEG45367.1 - 2.5e-33 115.6 0.1 2.9e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Heme oxygenase ANAPC4_WD40 PF12894.7 CEG45368.1 - 0.00092 19.5 0.0 0.23 11.8 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MFS_2 PF13347.6 CEG45370.1 - 5.9e-25 87.7 32.2 1.1e-20 73.6 9.0 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 CEG45370.1 - 2.7e-12 46.3 33.8 8.6e-08 31.5 14.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily PGM_PMM_I PF02878.16 CEG45371.1 - 1.9e-33 115.1 0.0 4.4e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CEG45371.1 - 2.3e-23 82.8 0.0 7.9e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CEG45371.1 - 1.8e-16 60.3 0.1 3.3e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CEG45371.1 - 9.8e-07 28.9 0.0 6.8e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HTH_40 PF14493.6 CEG45371.1 - 0.16 12.5 0.1 4.7 7.7 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Arf PF00025.21 CEG45372.1 - 2.6e-62 209.3 0.0 3.2e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG45372.1 - 4.1e-14 52.8 0.1 5.8e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG45372.1 - 2.8e-10 40.0 0.1 3.5e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEG45372.1 - 9.9e-10 38.1 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEG45372.1 - 2.4e-09 36.8 1.1 1.3e-07 31.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEG45372.1 - 1.9e-05 24.1 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG45372.1 - 3e-05 24.1 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CEG45372.1 - 0.066 13.7 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 CEG45372.1 - 0.081 12.8 0.3 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 CEG45372.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase OB_NTP_bind PF07717.16 CEG45373.1 - 4e-22 78.4 0.1 1.1e-21 76.9 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG45373.1 - 1.5e-15 57.4 0.0 6e-15 55.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CEG45373.1 - 1.2e-13 51.3 0.0 1.2e-13 51.3 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 CEG45373.1 - 1.1e-11 44.9 0.5 3.5e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 CEG45373.1 - 8.4e-06 26.1 0.2 3e-05 24.3 0.2 2.1 1 0 0 1 1 1 1 RWD domain AAA_19 PF13245.6 CEG45373.1 - 0.00015 22.1 0.0 0.0006 20.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEG45373.1 - 0.0015 17.7 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CEG45373.1 - 0.0028 17.9 0.4 0.019 15.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain dsrm PF00035.26 CEG45373.1 - 0.012 16.2 0.0 0.038 14.7 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Rad17 PF03215.15 CEG45373.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_2 PF07261.11 CEG45373.1 - 0.064 13.0 0.1 0.25 11.1 0.1 2.0 1 0 0 1 1 1 0 Replication initiation and membrane attachment SRP54 PF00448.22 CEG45373.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 CEG45373.1 - 0.078 12.3 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CEG45373.1 - 0.098 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Sorting_nexin PF03700.13 CEG45373.1 - 0.11 13.0 1.5 0.27 11.8 1.5 1.6 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain ABC_tran PF00005.27 CEG45373.1 - 0.11 13.0 0.9 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter UQ_con PF00179.26 CEG45375.1 - 2.1e-21 76.0 0.0 2.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_pol_B PF00136.21 CEG45376.1 - 6e-111 371.4 0.2 8.7e-111 370.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CEG45376.1 - 8.5e-46 156.0 2.4 1.8e-45 154.9 2.4 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CEG45376.1 - 5.2e-30 104.7 0.0 1e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CEG45376.1 - 2.2e-16 59.7 2.5 8.4e-16 57.8 2.5 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CEG45376.1 - 0.028 13.3 0.1 0.064 12.1 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral ApoLp-III PF07464.11 CEG45377.1 - 0.087 12.9 0.8 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.12 CEG45380.1 - 0.036 14.3 0.7 0.08 13.2 0.7 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF1279 PF06916.13 CEG45381.1 - 1.6e-20 73.4 0.3 2.6e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Imm63 PF15599.6 CEG45382.1 - 0.12 12.8 0.5 0.21 12.0 0.3 1.4 1 1 0 1 1 1 0 Immunity protein 63 LRR_6 PF13516.6 CEG45383.1 - 5.6e-05 22.9 0.1 8.4 6.7 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeat IQ PF00612.27 CEG45383.1 - 0.0071 16.0 0.2 0.0071 16.0 0.2 9.7 9 1 0 9 9 9 2 IQ calmodulin-binding motif TPR_16 PF13432.6 CEG45383.1 - 0.021 15.5 14.4 0.33 11.7 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat LRR_4 PF12799.7 CEG45383.1 - 0.025 15.0 1.5 0.43 11.1 0.3 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG45383.1 - 0.056 13.2 2.0 0.88 9.4 1.4 2.9 1 1 1 2 2 2 0 Leucine rich repeat DUF982 PF06169.12 CEG45383.1 - 1.2 9.2 5.2 25 5.0 3.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Ras PF00071.22 CEG45384.1 - 1.7e-55 187.0 0.0 2.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG45384.1 - 2e-31 108.7 0.0 3.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG45384.1 - 5.1e-13 48.8 0.0 7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG45384.1 - 5.3e-06 26.0 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG45384.1 - 2.1e-05 24.6 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG45384.1 - 0.00035 20.5 0.0 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEG45384.1 - 0.0016 18.0 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 CEG45384.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 CEG45384.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CEG45384.1 - 0.031 14.6 0.0 0.058 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CEG45384.1 - 0.036 14.2 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG45384.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CEG45384.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 CEG45384.1 - 0.17 11.6 0.0 0.83 9.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Thr_synth_N PF14821.6 CEG45385.1 - 1.3e-25 89.3 0.0 3.8e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 CEG45385.1 - 6.6e-18 65.1 0.0 1.7e-16 60.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tk-SP_N-pro PF18237.1 CEG45387.1 - 0.065 13.3 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Tk-SP N-propeptide domain Elicitin PF00964.17 CEG45388.1 - 0.11 12.5 4.5 2.5 8.3 0.6 2.4 1 1 1 2 2 2 0 Elicitin Transferase PF02458.15 CEG45391.1 - 3.5e-31 108.3 0.0 4.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF5564 PF17719.1 CEG45396.1 - 0.092 12.9 2.5 0.16 12.1 2.5 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5564) DUF664 PF04978.12 CEG45398.1 - 0.028 14.8 0.1 0.034 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF664) TB2_DP1_HVA22 PF03134.19 CEG45399.1 - 8.5e-30 102.5 4.1 1.3e-29 101.9 4.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3040 PF11239.8 CEG45399.1 - 0.083 13.2 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PI3_PI4_kinase PF00454.27 CEG45400.1 - 4.9e-30 105.2 0.5 1.3e-23 84.2 0.2 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 CEG45400.1 - 1.4e-17 63.5 4.4 1.4e-17 63.5 4.4 2.6 2 1 0 2 2 2 1 FYVE zinc finger PI3Ka PF00613.20 CEG45400.1 - 2e-08 33.9 0.8 3.6e-05 23.3 0.1 2.6 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) F-box-like PF12937.7 CEG45400.1 - 0.022 14.7 0.1 0.059 13.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF4135 PF13575.6 CEG45400.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) FYVE_2 PF02318.16 CEG45400.1 - 6.9 6.9 13.1 0.034 14.4 1.0 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger Kinesin PF00225.23 CEG45401.1 - 1.4e-91 306.9 0.1 2.7e-91 305.9 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG45401.1 - 4.5e-27 94.8 0.0 1.3e-26 93.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding SlyX PF04102.12 CEG45401.1 - 0.011 16.4 3.7 0.011 16.4 3.7 3.0 2 0 0 2 2 2 0 SlyX DUF641 PF04859.12 CEG45401.1 - 2.6 8.4 9.9 0.25 11.7 1.7 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Nup54 PF13874.6 CEG45401.1 - 3.3 7.8 16.1 0.93 9.6 3.7 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 CEG45401.1 - 6.4 4.6 7.5 0.18 9.7 0.3 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 CEG45401.1 - 9.7 6.4 9.9 1.9 8.7 3.7 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AA_kinase PF00696.28 CEG45402.1 - 1.4e-39 136.1 0.4 2.5e-39 135.3 0.4 1.4 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 CEG45402.1 - 2.6e-37 128.4 0.1 7e-37 127.0 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CEG45402.1 - 3.4e-05 24.5 0.0 0.00014 22.5 0.0 2.2 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 CEG45402.1 - 0.0042 16.8 1.2 0.088 12.6 0.0 3.6 3 0 0 3 3 3 1 ACT domain DUF2007 PF09413.10 CEG45402.1 - 0.017 15.3 0.0 1.5 9.0 0.0 2.9 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein Sacchrp_dh_NADP PF03435.18 CEG45402.1 - 0.054 13.8 0.1 0.64 10.3 0.0 2.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACT PF01842.25 CEG45402.1 - 0.089 12.6 0.4 0.81 9.5 0.0 2.7 3 0 0 3 3 3 0 ACT domain Pkinase PF00069.25 CEG45403.1 - 4.3e-72 242.6 0.2 6.3e-72 242.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45403.1 - 3e-41 141.4 0.2 5e-41 140.7 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 CEG45403.1 - 6.1e-14 51.6 0.1 6.1e-12 45.2 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CEG45403.1 - 2.3e-10 40.8 0.8 1.6e-08 34.8 0.2 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG45403.1 - 1.1e-09 37.1 1.3 1.2e-07 30.7 0.8 3.1 3 0 0 3 3 3 1 EF hand Kinase-like PF14531.6 CEG45403.1 - 2e-08 33.9 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG45403.1 - 9.6e-08 31.6 0.2 2.3e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEG45403.1 - 7.9e-07 28.3 0.6 1.4e-06 27.5 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain EF-hand_6 PF13405.6 CEG45403.1 - 1e-05 25.1 2.1 0.054 13.5 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain APH PF01636.23 CEG45403.1 - 0.00065 19.7 1.6 0.11 12.4 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family EF-hand_5 PF13202.6 CEG45403.1 - 0.0013 18.1 0.3 0.0059 16.0 0.5 1.9 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 CEG45403.1 - 0.0089 16.0 0.1 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand BRCT PF00533.26 CEG45403.1 - 0.02 15.3 0.0 0.087 13.2 0.0 2.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SPARC_Ca_bdg PF10591.9 CEG45403.1 - 0.063 13.6 3.2 3.8 7.9 0.2 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region YrbL-PhoP_reg PF10707.9 CEG45403.1 - 0.069 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CENP-Q PF13094.6 CEG45404.1 - 0.0029 17.8 2.0 0.0035 17.5 2.0 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PRKCSH_1 PF13015.6 CEG45406.1 - 0.003 17.3 0.2 0.0076 15.9 0.2 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ephrin_rec_like PF07699.13 CEG45406.1 - 0.0067 16.2 57.6 0.01 15.6 0.7 8.5 5 3 4 9 9 9 7 Putative ephrin-receptor like OCD_Mu_crystall PF02423.15 CEG45407.1 - 0.0094 14.9 0.6 0.012 14.6 0.6 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF2379 PF09543.10 CEG45407.1 - 0.031 14.5 0.2 0.038 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) GRP PF07172.11 CEG45408.1 - 4.4e-06 27.3 15.5 5.9e-06 26.9 15.5 1.3 1 0 0 1 1 1 1 Glycine rich protein family TMEM138 PF14935.6 CEG45409.1 - 0.021 15.5 0.3 0.037 14.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 138 HCMV_UL139 PF12507.8 CEG45411.1 - 0.0083 16.5 2.6 2 8.8 0.3 2.1 1 1 1 2 2 2 2 Human Cytomegalovirus UL139 protein DUF3834 PF12916.7 CEG45412.1 - 0.0075 15.5 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3834) DUF2815 PF10991.8 CEG45412.1 - 0.025 14.5 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2815) Edc3_linker PF16598.5 CEG45412.1 - 0.062 14.0 0.7 0.062 14.0 0.7 1.9 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Pkinase PF00069.25 CEG45413.1 - 8.6e-71 238.4 0.0 1.1e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45413.1 - 1.2e-36 126.3 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45413.1 - 1.1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG45413.1 - 9.1e-06 25.2 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEG45413.1 - 6.2e-05 22.0 0.1 0.00017 20.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG45413.1 - 0.0036 17.2 1.4 0.015 15.2 0.6 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEG45413.1 - 0.0061 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CEG45413.1 - 0.03 13.9 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 CEG45413.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fer4_20 PF14691.6 CEG45413.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Prefoldin_2 PF01920.20 CEG45417.1 - 5.4e-15 55.3 4.6 7.7e-15 54.8 4.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Fibrillarin PF01269.17 CEG45417.1 - 0.014 14.5 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Fibrillarin K-box PF01486.17 CEG45417.1 - 0.076 13.2 4.2 0.97 9.6 1.6 2.3 2 0 0 2 2 2 0 K-box region Vir_act_alpha_C PF10400.9 CEG45417.1 - 0.44 11.3 3.6 3.8 8.3 0.2 2.1 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF4140 PF13600.6 CEG45417.1 - 0.55 10.7 6.2 8.3 6.9 1.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CEG45417.1 - 1.1 9.1 10.4 1.7 8.4 0.4 2.7 2 1 1 3 3 3 0 Septum formation initiator RRP14 PF15459.6 CEG45417.1 - 9.2 7.0 8.4 13 6.4 0.9 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Pkinase PF00069.25 CEG45419.1 - 8.6e-54 182.7 0.0 1.3e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45419.1 - 1.6e-25 89.9 0.0 3e-25 89.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45419.1 - 4.1e-06 26.3 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEG45419.1 - 0.0038 16.9 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEG45419.1 - 0.0044 16.4 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG45419.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TSC22 PF01166.18 CEG45419.1 - 0.038 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Pkinase_fungal PF17667.1 CEG45419.1 - 0.051 12.3 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CEG45419.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PCI PF01399.27 CEG45424.1 - 2.8e-14 53.5 0.3 1e-13 51.7 0.1 2.0 2 0 0 2 2 2 1 PCI domain UCH PF00443.29 CEG45424.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase NiFe-hyd_HybE PF11939.8 CEG45424.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE HTH_psq PF05225.16 CEG45425.1 - 5.9e-05 22.7 0.2 0.00036 20.2 0.1 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 CEG45425.1 - 0.097 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CEG45425.1 - 0.1 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 CEG45427.1 - 0.00019 21.1 0.3 0.00058 19.5 0.3 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEG45427.1 - 0.0087 16.2 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Lipase_GDSL_2 PF13472.6 CEG45427.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family HTH_23 PF13384.6 CEG45427.1 - 0.082 12.7 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Flagellin_C PF00700.21 CEG45427.1 - 0.14 12.5 1.9 0.89 10.0 0.8 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region PI3_PI4_kinase PF00454.27 CEG45432.1 - 3.2e-32 112.3 0.0 2.7e-23 83.1 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 CEG45432.1 - 8.2e-05 23.1 0.0 0.00034 21.1 0.0 2.1 1 0 0 1 1 1 1 PH domain DUF4135 PF13575.6 CEG45432.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Rad52_Rad22 PF04098.15 CEG45433.1 - 1.1e-40 139.1 0.0 1.1e-40 139.1 0.0 2.1 2 1 0 2 2 2 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 CEG45433.1 - 0.0047 17.0 26.6 0.0077 16.3 26.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CEG45433.1 - 1 6.4 13.3 1.2 6.2 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 CEG45433.1 - 1.7 6.8 34.7 2.3 6.4 34.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mlo PF03094.15 CEG45434.1 - 0.0002 19.9 14.3 0.0043 15.5 0.4 2.8 3 0 0 3 3 3 2 Mlo family Spc110_C PF18520.1 CEG45434.1 - 0.0005 19.6 0.1 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 Spindle pole body component 110 C-terminal domain PACT_coil_coil PF10495.9 CEG45434.1 - 0.0022 18.5 1.4 0.0065 17.0 1.4 1.8 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cellulose_synt PF03552.14 CEG45434.1 - 0.43 9.0 1.7 0.99 7.8 1.7 1.5 1 0 0 1 1 1 0 Cellulose synthase Ctr PF04145.15 CEG45434.1 - 0.56 10.8 0.1 0.56 10.8 0.1 2.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF4834 PF16118.5 CEG45434.1 - 2.8 9.0 0.0 2.8 9.0 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 CEG45434.1 - 7.6 6.9 6.2 13 6.2 0.5 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-C2H2 PF00096.26 CEG45435.1 - 0.00092 19.5 5.6 0.22 12.1 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEG45435.1 - 0.0011 19.2 4.6 0.013 15.8 0.9 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEG45435.1 - 0.0014 19.3 5.0 0.85 10.6 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 CEG45435.1 - 0.002 18.0 1.4 0.54 10.1 0.0 2.3 1 1 1 2 2 2 2 Rad50 zinc hook motif zf-Di19 PF05605.12 CEG45435.1 - 0.0069 16.7 4.1 0.13 12.6 0.7 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CEG45435.1 - 0.0099 15.9 2.1 0.037 14.0 0.9 2.2 1 1 1 2 2 2 1 C2H2-type zinc finger LIM PF00412.22 CEG45435.1 - 0.032 14.5 0.9 0.069 13.4 0.9 1.5 1 1 0 1 1 1 0 LIM domain DZR PF12773.7 CEG45435.1 - 0.034 14.2 0.3 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon CpXC PF14353.6 CEG45435.1 - 0.13 12.4 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 CpXC protein CoiA PF06054.11 CEG45435.1 - 0.22 10.6 0.4 0.32 10.1 0.4 1.1 1 0 0 1 1 1 0 Competence protein CoiA-like family zf-MIZ PF02891.20 CEG45435.1 - 0.26 11.1 1.6 0.41 10.4 1.6 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C2HC_2 PF13913.6 CEG45435.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CEG45435.1 - 0.59 10.7 5.2 1.7 9.2 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Sec23_trunk PF04811.15 CEG45436.1 - 6.2e-74 248.6 0.0 9.2e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEG45436.1 - 5.3e-28 96.9 0.1 1.1e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEG45436.1 - 7.8e-19 68.2 0.0 2.7e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEG45436.1 - 1.9e-16 59.8 3.4 3.8e-16 58.8 3.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEG45436.1 - 8.3e-09 35.2 0.0 6.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat MRNIP PF15749.5 CEG45436.1 - 0.024 15.4 0.5 0.045 14.5 0.5 1.4 1 0 0 1 1 1 0 MRN-interacting protein Fe_hyd_lg_C PF02906.14 CEG45438.1 - 1.5e-66 224.5 0.0 1e-64 218.6 0.0 2.3 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 CEG45438.1 - 3.6e-09 36.6 0.9 1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Iron hydrogenase small subunit Fcf1 PF04900.12 CEG45438.1 - 0.009 16.4 0.1 0.029 14.8 0.1 1.9 1 0 0 1 1 1 1 Fcf1 TOM6p PF15184.6 CEG45438.1 - 0.18 11.6 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog UbiA PF01040.18 CEG45439.1 - 6.2e-55 186.2 15.5 9.2e-55 185.7 15.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Rieske PF00355.26 CEG45439.1 - 0.055 13.4 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain TrbC PF04956.13 CEG45439.1 - 0.34 11.1 6.1 0.073 13.3 1.0 2.3 2 1 0 2 2 2 0 TrbC/VIRB2 family DUF1398 PF07166.11 CEG45440.1 - 0.084 12.9 0.2 0.1 12.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) TERF2_RBM PF16772.5 CEG45442.1 - 0.07 12.6 0.0 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif fn3 PF00041.21 CEG45443.1 - 0.0029 17.9 0.3 0.015 15.6 0.1 2.1 1 1 1 2 2 2 1 Fibronectin type III domain TPR_8 PF13181.6 CEG45446.1 - 0.00025 21.0 0.9 0.0046 17.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG45446.1 - 0.0032 17.5 2.2 0.19 11.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEG45446.1 - 0.012 15.4 0.2 0.66 9.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45446.1 - 0.024 14.9 1.5 1.6 9.0 0.1 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45446.1 - 0.033 15.0 0.6 0.13 13.1 0.0 2.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45446.1 - 0.035 14.1 1.1 0.15 12.1 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4911 PF16256.5 CEG45446.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) RRM_1 PF00076.22 CEG45448.1 - 4.3e-34 116.1 0.1 8.7e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG45448.1 - 2.7e-14 53.0 0.5 2.1e-06 27.8 0.0 3.3 3 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CEG45448.1 - 8.1e-05 22.5 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 CEG45448.1 - 0.04 13.9 17.8 0.061 13.3 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEG45448.1 - 0.69 9.5 23.4 1.1 8.8 23.4 1.4 1 0 0 1 1 1 0 Spt20 family RCR PF12273.8 CEG45448.1 - 2.3 8.9 11.8 4.6 7.9 11.8 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Presenilin PF01080.17 CEG45448.1 - 4.3 6.0 5.8 5.3 5.7 5.8 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CEG45448.1 - 8.7 7.0 14.5 16 6.1 14.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.8 CEG45448.1 - 8.9 5.2 32.6 14 4.5 32.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Fzo_mitofusin PF04799.13 CEG45449.1 - 0.0089 15.6 1.3 0.016 14.8 1.3 1.3 1 0 0 1 1 1 1 fzo-like conserved region Med30 PF11315.8 CEG45449.1 - 0.031 14.5 0.4 0.031 14.5 0.4 1.5 2 0 0 2 2 2 0 Mediator complex subunit 30 NYD-SP28 PF14772.6 CEG45450.1 - 4.2e-27 94.1 10.6 4.2e-27 94.1 10.6 5.4 3 1 1 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 CEG45450.1 - 2.5e-15 56.3 1.2 2.5e-15 56.3 1.2 4.5 3 1 1 4 4 4 1 Sperm tail C-terminal domain DASH_Hsk3 PF08227.11 CEG45450.1 - 3.5 8.1 8.8 40 4.7 0.0 4.5 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like RRM_1 PF00076.22 CEG45452.1 - 2.5e-28 97.7 1.2 4.3e-12 45.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.14 CEG45453.1 - 3.5e-34 118.2 0.4 4.8e-34 117.7 0.4 1.2 1 0 0 1 1 1 1 MT-A70 AAA_33 PF13671.6 CEG45453.1 - 0.89 9.7 3.8 2.5 8.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain RVT_2 PF07727.14 CEG45455.1 - 7.1e-20 71.7 0.0 8.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ASH PF15780.5 CEG45456.1 - 4.6e-24 84.5 14.7 0.0095 16.1 0.0 12.7 14 0 0 14 14 14 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEG45456.1 - 2.9e-15 56.3 12.2 0.13 12.5 0.0 9.5 11 0 0 11 11 11 7 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CEG45456.1 - 5.9e-12 45.4 10.1 0.22 11.4 0.2 9.6 11 0 0 11 11 11 4 MSP (Major sperm protein) domain DUF1573 PF07610.11 CEG45456.1 - 5.1e-11 42.5 5.0 0.055 13.5 0.0 9.8 11 0 0 11 11 11 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 CEG45456.1 - 5e-08 33.1 8.2 1.4 9.2 0.0 9.4 9 0 0 9 9 9 1 Transmembrane protein 131-like fn3_6 PF17766.1 CEG45456.1 - 0.00063 19.9 2.3 1.2 9.4 0.0 4.5 4 1 0 4 4 4 2 Fibronectin type-III domain Hydrolase_4 PF12146.8 CEG45457.1 - 1e-11 44.5 0.0 4e-11 42.7 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG45457.1 - 6.1e-09 35.9 0.0 3.1e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG45457.1 - 4.4e-06 27.5 0.0 7.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CEG45457.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LETM1 PF07766.13 CEG45458.1 - 5.8e-48 163.6 2.0 7.3e-48 163.2 2.0 1.0 1 0 0 1 1 1 1 LETM1-like protein RPN6_N PF18055.1 CEG45459.1 - 1.7e-27 96.1 1.0 1.7e-27 96.1 1.0 3.0 3 1 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CEG45459.1 - 9.7e-16 58.2 5.0 1.4e-15 57.7 0.4 3.1 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 CEG45459.1 - 3.5e-09 36.2 0.0 7.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 CEG45459.1 - 0.0041 16.6 6.1 0.0041 16.6 6.1 1.9 2 1 0 2 2 2 1 MalT-like TPR region Rx_N PF18052.1 CEG45459.1 - 0.0046 17.2 1.6 0.013 15.8 0.1 2.4 2 0 0 2 2 2 1 Rx N-terminal domain RPN7 PF10602.9 CEG45459.1 - 0.014 15.1 0.3 0.034 13.8 0.3 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF1780 PF08682.10 CEG45460.1 - 0.2 11.3 0.0 0.25 11.0 0.0 1.0 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) zf-CCHC PF00098.23 CEG45461.1 - 2.2e-05 24.3 1.4 4.2e-05 23.4 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEG45461.1 - 0.0018 17.9 1.1 0.0033 17.1 1.1 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEG45461.1 - 0.0031 17.3 2.3 0.0055 16.5 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 CEG45461.1 - 0.0061 16.9 0.7 0.0095 16.3 0.5 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 CEG45461.1 - 0.082 12.9 1.4 0.14 12.1 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_3 PF13456.6 CEG45462.1 - 0.026 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Arm-DNA-bind_3 PF13356.6 CEG45462.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 2 0 0 2 2 2 0 Arm DNA-binding domain RXLR_WY PF18634.1 CEG45465.1 - 0.011 15.6 0.9 0.061 13.3 0.2 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain SIP1 PF04938.12 CEG45465.1 - 0.033 13.9 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) HRDC PF00570.23 CEG45465.1 - 0.051 13.6 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 HRDC domain polyprenyl_synt PF00348.17 CEG45472.1 - 4.3e-62 209.5 0.0 5e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Baculo_p33 PF05214.12 CEG45472.1 - 0.11 12.2 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Baculovirus P33 DUF2514 PF10721.9 CEG45475.1 - 0.14 12.2 0.6 0.21 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Retrotran_gag_2 PF14223.6 CEG45477.1 - 1.1e-21 76.9 0.2 1.4e-21 76.7 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG45477.1 - 0.00023 21.1 1.7 0.00033 20.6 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 CEG45477.1 - 0.001 19.5 0.2 0.0013 19.1 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 CEG45477.1 - 0.025 14.5 1.1 0.045 13.7 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEG45477.1 - 0.035 13.8 1.4 0.057 13.2 1.4 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Myb_DNA-binding PF00249.31 CEG45484.1 - 2.9e-08 33.8 2.9 7.4e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG45484.1 - 3.3e-06 27.2 4.4 0.001 19.3 0.3 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 CEG45484.1 - 0.051 13.6 0.1 0.23 11.5 0.1 2.1 1 1 0 1 1 1 0 SLIDE Cnn_1N PF07989.11 CEG45484.1 - 0.84 9.8 4.6 0.56 10.4 1.2 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RRM_1 PF00076.22 CEG45485.1 - 3.9e-07 29.8 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG45485.1 - 0.017 15.1 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_23 PF13489.6 CEG45486.1 - 8.7e-17 61.4 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG45486.1 - 7.6e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG45486.1 - 8.5e-14 52.0 0.0 1.5e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG45486.1 - 1.9e-08 34.8 0.0 3.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG45486.1 - 4.1e-08 33.2 0.0 6.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG45486.1 - 9.6e-07 28.5 0.1 2.1e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.12 CEG45486.1 - 0.003 17.1 0.0 0.0074 15.8 0.0 1.6 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 CEG45486.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CEG45486.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain ETF_QO PF05187.13 CEG45487.1 - 2.4e-39 133.6 0.2 4.7e-39 132.7 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 CEG45487.1 - 2.1e-05 23.8 0.4 0.0014 17.8 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CEG45487.1 - 3.1e-05 23.4 0.0 0.0096 15.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 CEG45487.1 - 5.2e-05 23.0 0.5 0.1 12.2 0.5 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEG45487.1 - 0.00024 21.3 0.0 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEG45487.1 - 0.0024 17.0 0.3 0.0058 15.7 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Fer4_7 PF12838.7 CEG45487.1 - 0.011 16.3 3.1 0.033 14.8 3.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 CEG45487.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEG45487.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 CEG45487.1 - 0.069 11.8 0.2 0.11 11.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CEG45487.1 - 0.074 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEG45487.1 - 0.087 13.4 0.1 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEG45487.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CEG45487.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DnaJ_C PF01556.18 CEG45488.1 - 2e-37 128.5 0.0 2.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG45488.1 - 2.3e-27 94.9 1.2 4.2e-27 94.0 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain Pterin_4a PF01329.19 CEG45488.1 - 0.1 12.8 0.2 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Phage_Orf51 PF06194.11 CEG45488.1 - 0.12 12.4 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 RNA_pol_Rpc82 PF05645.13 CEG45489.1 - 1.2e-08 35.0 8.3 1.5e-05 24.9 1.8 5.0 3 3 0 4 4 4 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CEG45489.1 - 1.6e-08 34.5 4.8 1.9e-06 27.9 1.3 3.9 3 1 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CEG45489.1 - 0.00052 19.8 4.8 0.002 18.0 0.1 3.4 2 1 1 3 3 3 1 TFIIE alpha subunit DUF2880 PF11082.8 CEG45489.1 - 0.054 13.8 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) preSET_CXC PF18264.1 CEG45490.1 - 6.6e-05 23.3 23.3 6.6e-05 23.3 23.3 3.6 2 1 1 3 3 3 1 CXC domain SET PF00856.28 CEG45490.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 SET domain LSM PF01423.22 CEG45491.1 - 9.9e-08 31.6 0.2 1.5e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF211 PF02680.14 CEG45491.1 - 0.038 14.2 0.1 0.07 13.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 MIOX PF05153.15 CEG45492.1 - 3.8e-101 337.8 3.0 4.8e-101 337.5 3.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 CEG45492.1 - 0.017 15.1 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase HD PF01966.22 CEG45492.1 - 0.059 13.6 0.4 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 HD domain cNMP_binding PF00027.29 CEG45493.1 - 1.3e-37 127.7 0.8 1.4e-18 66.7 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CEG45493.1 - 0.0044 16.7 4.1 0.13 12.0 0.3 2.5 2 0 0 2 2 2 2 Cupin domain NIR_SIR_ferr PF03460.17 CEG45493.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain IRK_N PF08466.10 CEG45493.1 - 0.079 13.1 2.0 0.19 11.9 2.0 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal Cupin_3 PF05899.12 CEG45493.1 - 0.31 10.8 2.7 3.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Carn_acyltransf PF00755.20 CEG45495.1 - 2.7e-195 650.4 0.0 3.1e-195 650.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF4719 PF15843.5 CEG45496.1 - 0.0006 20.0 1.1 0.00094 19.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4719) MlaE PF02405.16 CEG45498.1 - 0.073 12.7 0.2 0.073 12.7 0.2 2.1 2 0 0 2 2 2 0 Permease MlaE DUF1853 PF08907.11 CEG45499.1 - 7.1e-20 71.9 0.0 1e-10 41.8 0.0 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1853) tRNA_edit PF04073.15 CEG45499.1 - 5.6e-16 58.7 0.1 1.6e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DNA_pol_A_exo1 PF01612.20 CEG45499.1 - 2.7e-10 40.3 0.0 1.2e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease PUB PF09409.10 CEG45500.1 - 1.4e-20 73.0 0.0 3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain SOBP PF15279.6 CEG45500.1 - 0.018 15.7 7.8 0.024 15.2 7.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IL5 PF02025.15 CEG45501.1 - 0.11 12.8 0.3 0.99 9.7 0.0 2.0 2 0 0 2 2 2 0 Interleukin 5 DUF1079 PF06435.11 CEG45502.1 - 0.11 12.7 0.4 8.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Alg6_Alg8 PF03155.15 CEG45503.1 - 8.4e-160 532.9 26.7 9.9e-160 532.7 26.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family COPIIcoated_ERV PF07970.12 CEG45504.1 - 5.5e-27 95.1 1.1 1.3e-26 93.9 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEG45504.1 - 8.8e-22 77.3 0.0 1.8e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 CEG45504.1 - 1.9e-19 69.6 0.0 4.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG45504.1 - 2.9e-07 30.9 0.0 7.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG45504.1 - 0.041 14.2 0.0 3.2 8.1 0.0 3.6 3 1 1 4 4 4 0 Thioredoxin-like DUF3817 PF12823.7 CEG45505.1 - 0.063 14.1 0.7 0.1 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Fungal_KA1 PF16797.5 CEG45507.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Retrotran_gag_2 PF14223.6 CEG45508.1 - 0.00079 19.1 3.8 0.65 9.7 0.1 3.1 1 1 2 3 3 3 3 gag-polypeptide of LTR copia-type Hist_deacetyl PF00850.19 CEG45510.1 - 9.5e-68 228.9 0.0 2.9e-67 227.3 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylase domain PHD PF00628.29 CEG45510.1 - 5.7e-11 42.1 2.9 1.2e-10 41.1 2.9 1.6 1 0 0 1 1 1 1 PHD-finger AP2 PF00847.20 CEG45510.1 - 1.3e-07 31.8 0.9 0.00054 20.1 0.2 2.6 2 0 0 2 2 2 2 AP2 domain DDE_1 PF03184.19 CEG45513.1 - 9.8e-10 38.4 0.1 1.1e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PI3K_1B_p101 PF10486.9 CEG45515.1 - 0.22 9.3 5.0 0.27 9.0 5.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FYVE PF01363.21 CEG45516.1 - 2.6e-07 30.7 14.4 2.6e-07 30.7 14.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger START PF01852.19 CEG45516.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 START domain FYVE_2 PF02318.16 CEG45516.1 - 7.4 6.8 13.3 0.16 12.2 5.9 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger Imm19 PF15563.6 CEG45517.1 - 0.0011 18.6 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Immunity protein 19 Ank_2 PF12796.7 CEG45518.1 - 4.2e-31 107.4 12.5 1.8e-11 44.5 0.8 6.2 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45518.1 - 3.8e-24 84.7 15.5 3.1e-10 40.4 0.1 8.2 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG45518.1 - 1.1e-23 83.0 10.3 3.3e-10 40.0 0.3 8.3 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG45518.1 - 3.2e-21 73.1 19.0 9.9e-05 22.5 0.0 12.1 13 0 0 13 13 13 4 Ankyrin repeat Ank PF00023.30 CEG45518.1 - 4.8e-21 74.2 28.3 3.9e-06 27.1 0.0 9.9 9 1 0 9 9 9 6 Ankyrin repeat Glyco_hydro_31 PF01055.26 CEG45520.1 - 2.6e-150 501.5 0.3 4.5e-150 500.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CEG45520.1 - 1.5e-28 99.4 0.0 3.9e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_25 PF03423.13 CEG45520.1 - 2.9e-15 56.4 9.8 1.6e-07 31.5 2.5 2.8 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 CEG45520.1 - 6e-09 36.4 7.7 0.00023 21.7 0.7 2.8 3 0 0 3 3 3 2 Starch/carbohydrate-binding module (family 53) Gal_mutarotas_2 PF13802.6 CEG45520.1 - 5.8e-08 32.9 3.9 6.3e-08 32.8 0.0 2.9 4 0 0 4 4 4 1 Galactose mutarotase-like CBM26 PF16738.5 CEG45520.1 - 0.00048 20.3 6.4 0.069 13.4 1.2 3.0 2 0 0 2 2 2 2 Starch-binding module 26 DUF2247 PF10004.9 CEG45520.1 - 0.089 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) PhnH PF05845.12 CEG45522.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Glyoxal_oxid_N PF07250.11 CEG45523.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus QRPTase_C PF01729.19 CEG45526.1 - 7.2e-56 188.6 0.0 9.5e-56 188.2 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CEG45526.1 - 3.5e-19 68.6 0.0 8.8e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain RRM_2 PF04059.12 CEG45527.1 - 1.9e-45 153.0 1.3 3.3e-45 152.2 1.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CEG45527.1 - 0.00019 21.2 0.1 0.017 14.9 0.2 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 CEG45527.1 - 0.00044 20.3 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 Smg-4/UPF3 family zf-B_box PF00643.24 CEG45527.1 - 0.004 17.3 6.4 0.008 16.3 6.4 1.5 1 0 0 1 1 1 1 B-box zinc finger BRAP2 PF07576.12 CEG45527.1 - 0.041 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 BRCA1-associated protein 2 C1_2 PF03107.16 CEG45527.1 - 0.1 12.9 5.2 0.23 11.8 5.2 1.6 1 0 0 1 1 1 0 C1 domain zf-HIT PF04438.16 CEG45527.1 - 2.6 8.0 5.0 6 6.8 5.0 1.6 1 0 0 1 1 1 0 HIT zinc finger SNF2_N PF00176.23 CEG45528.1 - 1.6e-57 194.9 1.1 2.7e-55 187.5 0.1 3.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG45528.1 - 7e-16 58.6 0.0 1.7e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 CEG45528.1 - 3.8e-08 33.1 4.7 3.8e-08 33.1 4.7 4.3 5 0 0 5 5 3 1 PHD-finger zf-PARP PF00645.18 CEG45528.1 - 4.1e-08 34.0 0.0 4.1e-08 34.0 0.0 3.3 3 1 0 3 3 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 CEG45528.1 - 1.9e-07 30.9 5.3 1.9e-07 30.9 5.3 4.3 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG45528.1 - 2.4e-06 27.3 6.5 2.4e-06 27.3 6.5 3.8 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG45528.1 - 3.6e-05 23.5 6.3 3.6e-05 23.5 6.3 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG45528.1 - 0.00011 22.5 6.7 0.00011 22.5 6.7 3.4 3 0 0 3 3 2 2 Ring finger domain DEAD PF00270.29 CEG45528.1 - 0.00011 22.0 0.1 0.052 13.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase zf-RING_5 PF14634.6 CEG45528.1 - 0.00035 20.5 6.5 0.00035 20.5 6.5 4.3 5 1 0 5 5 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEG45528.1 - 0.0027 17.8 6.5 0.0027 17.8 6.5 2.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEG45528.1 - 0.0067 16.3 6.0 0.0067 16.3 6.0 2.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEG45528.1 - 0.01 15.8 3.5 0.01 15.8 3.5 2.7 2 1 0 2 2 1 0 RING-type zinc-finger zf-C2HC_2 PF13913.6 CEG45528.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CEG45528.1 - 1.5 8.9 10.2 1.1 9.4 0.1 4.3 4 0 0 4 4 4 0 BED zinc finger zf-rbx1 PF12678.7 CEG45528.1 - 1.7 9.0 20.3 0.56 10.5 0.5 3.0 3 0 0 3 3 2 0 RING-H2 zinc finger domain DUF334 PF03904.13 CEG45532.1 - 0.23 11.0 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RPA_interact_C PF14768.6 CEG45533.1 - 1.5e-10 41.5 8.5 1.5e-10 41.5 8.5 3.0 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 CEG45533.1 - 1.3e-07 31.1 3.1 6.7e-07 28.8 3.1 2.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal SANT_DAMP1_like PF16282.5 CEG45535.1 - 0.05 13.8 0.2 0.061 13.5 0.2 1.1 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 T4BSS_DotI_IcmL PF11393.8 CEG45535.1 - 0.14 11.6 0.4 0.14 11.6 0.4 1.0 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component RXLR PF16810.5 CEG45537.1 - 0.051 14.0 0.2 2.6 8.5 0.1 2.3 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DicB PF05358.11 CEG45538.1 - 0.018 15.2 0.1 0.088 13.0 0.0 2.3 2 0 0 2 2 2 0 DicB protein Porin_10 PF14121.6 CEG45538.1 - 0.059 12.0 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative porin Ank_2 PF12796.7 CEG45539.1 - 1.7e-70 233.6 36.8 4.1e-15 56.1 1.4 16.0 10 5 6 16 16 16 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45539.1 - 1.3e-49 166.0 43.7 1.8e-06 28.3 0.1 20.0 15 6 7 23 23 23 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG45539.1 - 7.3e-38 128.1 35.3 7.2e-06 26.2 0.3 19.9 16 4 7 23 23 23 8 Ankyrin repeats (many copies) PARP PF00644.20 CEG45539.1 - 2.3e-35 121.9 0.0 9.6e-32 110.1 0.0 2.6 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Ank_3 PF13606.6 CEG45539.1 - 7.7e-32 105.8 47.8 0.0048 17.3 0.0 23.9 27 1 0 27 27 27 8 Ankyrin repeat Ank PF00023.30 CEG45539.1 - 5.6e-31 105.6 57.5 6.4e-05 23.2 0.1 22.9 27 0 0 27 27 27 8 Ankyrin repeat WGR PF05406.15 CEG45539.1 - 2.6e-19 69.1 0.1 6.5e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 CEG45539.1 - 1.4e-06 28.5 0.1 3.1e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain DUF2605 PF10792.9 CEG45540.1 - 0.057 13.4 1.2 0.098 12.6 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) HTH_33 PF13592.6 CEG45541.1 - 0.0017 18.0 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn helix DDE_1 PF03184.19 CEG45541.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 CEG45541.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 CEG45541.1 - 0.043 13.8 1.0 0.46 10.6 0.7 2.6 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF4099 PF13351.6 CEG45541.1 - 0.17 12.2 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4099) EF-hand_13 PF17958.1 CEG45543.1 - 1.2e-33 114.8 0.0 3.7e-33 113.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CEG45543.1 - 1.2e-18 67.3 4.3 2.7e-15 56.6 1.0 3.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG45543.1 - 1.8e-06 27.4 0.1 0.0089 15.9 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CEG45543.1 - 6e-05 22.3 3.1 0.75 9.5 0.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 CEG45543.1 - 0.004 16.6 0.4 0.52 9.9 0.0 2.9 3 0 0 3 3 3 1 EF hand DUF4187 PF13821.6 CEG45543.1 - 0.022 14.6 0.1 0.063 13.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Pkinase PF00069.25 CEG45544.1 - 2.1e-64 217.5 0.0 3.5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45544.1 - 8.1e-33 113.8 0.0 1.3e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45544.1 - 8.6e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_4 PF14555.6 CEG45544.1 - 0.00046 19.9 0.0 0.45 10.4 0.0 2.8 2 0 0 2 2 2 2 UBA-like domain APH PF01636.23 CEG45544.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEG45544.1 - 0.054 13.1 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CEG45544.1 - 0.59 10.9 2.9 0.64 10.8 0.7 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain DAGAT PF03982.13 CEG45545.1 - 4.2e-53 180.2 0.0 5.2e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2431 PF10354.9 CEG45547.1 - 3.3e-48 164.1 0.0 5.8e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.8 CEG45547.1 - 0.018 15.3 0.1 0.041 14.2 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Rhodanese PF00581.20 CEG45548.1 - 7.2e-23 81.2 0.0 5.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SAP PF02037.27 CEG45550.1 - 0.075 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 SAP domain PI3_PI4_kinase PF00454.27 CEG45551.1 - 8.5e-30 104.4 0.0 1.2e-23 84.2 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase RVT_3 PF13456.6 CEG45551.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like PI3Ka PF00613.20 CEG45551.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Retrotran_gag_2 PF14223.6 CEG45552.1 - 7e-40 135.9 0.1 7.7e-40 135.7 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Clat_adaptor_s PF01217.20 CEG45552.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain ATG16 PF08614.11 CEG45554.1 - 5.9e-05 23.4 2.2 0.00012 22.4 2.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 CEG45554.1 - 0.0043 17.2 3.1 0.008 16.3 3.1 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 CEG45554.1 - 0.0065 16.4 4.7 0.012 15.6 4.7 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain Prefoldin_2 PF01920.20 CEG45554.1 - 0.029 14.3 6.0 1.9 8.5 1.0 2.6 1 1 1 2 2 2 0 Prefoldin subunit Med4 PF10018.9 CEG45554.1 - 0.038 13.7 3.5 0.07 12.8 3.5 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Cob_adeno_trans PF01923.18 CEG45554.1 - 0.1 12.7 1.2 0.24 11.5 1.2 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Mod_r PF07200.13 CEG45554.1 - 0.16 12.1 6.8 0.28 11.3 6.5 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1640 PF07798.11 CEG45554.1 - 0.16 12.0 5.1 0.26 11.3 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) RRP36 PF06102.12 CEG45554.1 - 0.33 10.9 4.6 0.61 10.0 4.6 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FlaC_arch PF05377.11 CEG45554.1 - 0.37 11.2 2.8 1.4 9.4 0.1 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 CEG45554.1 - 0.42 10.9 3.6 6.4 7.1 2.5 2.9 1 1 0 2 2 2 0 Rx N-terminal domain CENP-H PF05837.12 CEG45554.1 - 0.44 11.0 4.9 0.73 10.3 4.0 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 CEG45554.1 - 0.62 10.2 6.7 9.4 6.4 2.3 2.7 1 1 1 2 2 2 0 bZIP transcription factor zf-C4pol PF14260.6 CEG45554.1 - 1.2 9.7 5.2 1.2 9.6 2.9 2.2 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta MFS_4 PF06779.14 CEG45555.1 - 0.21 10.9 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Glyco_transf_36 PF06165.11 CEG45556.1 - 0.027 13.9 0.1 0.029 13.8 0.1 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 36 Rubis-subs-bind PF09273.11 CEG45557.1 - 1.9e-15 57.7 0.0 4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 CEG45557.1 - 1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 SET domain Ten1_2 PF15490.6 CEG45558.1 - 3.6e-22 78.3 0.9 4.2e-22 78.1 0.9 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit SLBP_RNA_bind PF15247.6 CEG45559.1 - 3e-29 100.9 1.5 6.3e-29 99.9 1.5 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Miga PF10265.9 CEG45559.1 - 0.0037 16.3 0.0 0.004 16.2 0.0 1.0 1 0 0 1 1 1 1 Mitoguardin SLT_L PF14718.6 CEG45559.1 - 0.15 12.2 0.2 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain GMP_PDE_delta PF05351.11 CEG45560.1 - 8.3e-60 201.4 0.1 1e-59 201.1 0.1 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit RVT_2 PF07727.14 CEG45564.1 - 6.9e-34 117.5 0.2 1.1e-33 116.9 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 CEG45565.1 - 1.9e-18 65.8 18.5 8.3e-06 26.0 0.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEG45565.1 - 1.4e-14 53.5 16.8 0.0017 19.0 0.9 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEG45565.1 - 5.7e-12 45.5 22.1 4.3e-08 33.2 0.8 5.8 5 1 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 CEG45565.1 - 0.00018 22.1 3.8 0.19 12.3 0.0 3.7 2 2 2 4 4 4 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEG45565.1 - 0.00021 21.5 6.9 0.095 13.0 3.9 3.4 1 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CEG45565.1 - 0.00073 19.2 12.3 0.14 12.0 0.0 4.2 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CEG45565.1 - 0.0015 18.2 7.9 0.47 10.3 0.4 3.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CEG45565.1 - 0.0023 17.9 6.9 0.47 10.5 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEG45565.1 - 0.0035 17.6 3.1 2.3 8.6 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CEG45565.1 - 0.0055 16.9 6.0 1.8 8.7 0.7 3.3 1 1 2 3 3 3 2 Aberrant zinc-finger CxC6 PF18721.1 CEG45565.1 - 0.091 13.0 8.4 0.44 10.8 0.7 2.6 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases DUF4729 PF15866.5 CEG45565.1 - 0.13 11.6 4.8 2.3 7.5 0.1 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4729) zf-C2H2_2 PF12756.7 CEG45565.1 - 0.22 11.9 6.3 5 7.5 1.3 3.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CEG45565.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 4 0 0 4 4 4 0 BED zinc finger zf-RRN7 PF11781.8 CEG45565.1 - 1.9 8.3 8.3 2.7 7.7 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_ZIC PF18366.1 CEG45565.1 - 2.1 8.5 5.8 9.1 6.5 0.1 4.0 5 0 0 5 5 5 0 Zic proteins zinc finger domain NST1 PF13945.6 CEG45569.1 - 0.0001 22.5 7.3 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 Salt tolerance down-regulator DUF4326 PF14216.6 CEG45569.1 - 0.031 15.0 0.0 0.54 11.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) DUF572 PF04502.13 CEG45570.1 - 3.8e-53 181.3 0.0 4.4e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C4_Topoisom PF01396.19 CEG45570.1 - 0.08 12.7 0.2 0.25 11.2 0.2 1.9 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Anti-TRAP PF15777.5 CEG45570.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein RabGAP-TBC PF00566.18 CEG45571.1 - 5.6e-05 22.9 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CDP-OH_P_transf PF01066.21 CEG45572.1 - 0.57 11.0 1.6 3.2 8.6 1.6 2.0 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Integrase_H2C2 PF17921.1 CEG45574.1 - 2.1e-13 50.1 0.1 2.1e-13 50.1 0.1 2.0 3 0 0 3 3 3 1 Integrase zinc binding domain Aldedh PF00171.22 CEG45576.1 - 2.4e-76 257.1 0.2 2.9e-76 256.8 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_Tyr PF07714.17 CEG45577.1 - 4e-55 186.9 0.0 5.2e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG45577.1 - 1.4e-51 175.4 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FAM195 PF14799.6 CEG45577.1 - 0.019 15.3 0.3 51 4.3 0.0 3.6 3 1 1 4 4 4 0 FAM195 family DIT1_PvcA PF05141.12 CEG45577.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Thioredoxin PF00085.20 CEG45578.1 - 2.6e-63 210.5 0.2 1.9e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CEG45578.1 - 6.2e-18 65.5 0.0 1.7e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CEG45578.1 - 1.3e-17 64.1 0.0 8e-09 35.3 0.0 2.2 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CEG45578.1 - 2.7e-15 56.8 2.1 2.9e-07 30.9 0.1 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG45578.1 - 1e-09 38.6 0.2 0.0093 16.3 0.0 4.1 2 2 2 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 CEG45578.1 - 2.1e-09 37.4 0.1 0.0032 17.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CEG45578.1 - 9.6e-09 35.2 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 CEG45578.1 - 1.8e-08 34.5 0.0 0.00088 19.2 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CEG45578.1 - 6.6e-06 25.9 0.0 0.0072 16.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29_N PF07912.13 CEG45578.1 - 7.1e-06 26.2 0.5 0.15 12.2 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain HyaE PF07449.11 CEG45578.1 - 7.6e-05 22.6 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 CEG45578.1 - 8.2e-05 22.3 0.3 0.079 12.7 0.1 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 CEG45578.1 - 0.0017 18.4 0.1 0.34 11.0 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain DUF836 PF05768.14 CEG45578.1 - 0.0034 17.7 0.0 1.5 9.3 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CEG45578.1 - 0.12 12.6 2.9 4.4 7.6 0.1 3.0 2 2 0 2 2 2 0 Glutaredoxin Med14 PF08638.11 CEG45579.1 - 2e-43 148.1 0.2 3.7e-43 147.2 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 EF1G PF00647.19 CEG45580.1 - 8.8e-40 135.1 0.2 1.9e-39 134.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CEG45580.1 - 9.3e-18 64.4 0.4 2e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEG45580.1 - 4.3e-15 55.7 0.1 1e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEG45580.1 - 6e-10 39.4 0.0 1.6e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEG45580.1 - 8.1e-10 38.6 0.1 1.8e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEG45580.1 - 2e-06 27.9 0.1 5.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CEG45580.1 - 1.9e-05 24.9 0.0 5.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CEG45580.1 - 0.022 15.1 0.2 0.42 10.9 0.0 2.7 2 1 0 2 2 2 0 Outer mitochondrial membrane transport complex protein HABP4_PAI-RBP1 PF04774.15 CEG45580.1 - 0.039 14.8 0.9 0.077 13.8 0.9 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family GST_N_5 PF18485.1 CEG45580.1 - 0.091 13.1 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ABC_tran PF00005.27 CEG45582.1 - 1.2e-19 71.2 0.0 2.3e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CEG45582.1 - 3.6e-05 23.6 30.9 0.0012 18.5 0.3 3.8 3 2 1 4 4 4 2 ABC transporter transmembrane region AAA_16 PF13191.6 CEG45582.1 - 0.0027 18.1 0.0 0.0084 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CEG45582.1 - 0.053 13.3 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 CEG45582.1 - 0.065 12.6 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 CEG45582.1 - 0.074 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CEG45582.1 - 0.094 12.6 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CEG45582.1 - 0.13 12.3 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEG45582.1 - 0.36 10.9 1.7 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Dynamin family AAA_29 PF13555.6 CEG45583.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain tRNA-synt_1c PF00749.21 CEG45585.1 - 4.1e-99 331.4 0.1 4.1e-99 331.4 0.1 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CEG45585.1 - 1.4e-35 122.8 0.0 2.5e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 CEG45585.1 - 4.9e-17 61.8 1.4 4.9e-17 61.8 1.4 2.0 1 1 0 1 1 1 1 WHEP-TRS domain GST_C_3 PF14497.6 CEG45585.1 - 0.00018 21.6 0.0 0.0043 17.2 0.0 3.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEG45585.1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 CEG45585.1 - 0.068 12.5 0.1 0.068 12.5 0.1 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Cation_efflux PF01545.21 CEG45586.1 - 2.6e-43 148.1 4.9 3.5e-43 147.7 4.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CEG45586.1 - 1.3e-10 41.3 2.4 1.7e-10 40.9 1.1 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF1269 PF06897.12 CEG45586.1 - 0.085 13.1 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Clat_adaptor_s PF01217.20 CEG45587.1 - 9.6e-08 32.1 2.1 1.2e-07 31.8 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Herpes_ori_bp PF02399.15 CEG45587.1 - 0.017 13.2 4.0 0.02 13.0 4.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein DUF668 PF05003.12 CEG45587.1 - 0.088 13.3 0.1 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF668) CobA_CobO_BtuR PF02572.15 CEG45587.1 - 0.87 9.8 3.7 4.3 7.6 0.4 2.3 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP WD40 PF00400.32 CEG45588.1 - 6.4e-17 61.6 10.1 0.00032 21.4 0.6 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG45588.1 - 9.1e-13 48.3 0.0 0.00017 21.9 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG45588.1 - 0.00018 20.6 0.1 0.0027 16.7 0.0 2.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEG45588.1 - 0.00019 20.9 0.0 0.027 13.8 0.0 3.4 3 1 0 3 3 3 1 WD40-like domain Mg_trans_NIPA PF05653.14 CEG45589.1 - 1.2e-29 103.3 15.4 1.9e-29 102.7 15.4 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEG45589.1 - 3.2e-05 24.1 1.8 3.2e-05 24.1 1.8 4.1 3 1 0 4 4 4 1 EamA-like transporter family Tetraspanin PF00335.20 CEG45589.1 - 0.0019 18.0 7.3 0.65 9.7 0.1 3.4 2 1 1 3 3 3 2 Tetraspanin family TMEM234 PF10639.9 CEG45589.1 - 0.083 12.9 1.6 0.16 12.0 0.1 2.2 2 1 0 2 2 2 0 Putative transmembrane family 234 INSIG PF07281.12 CEG45589.1 - 0.35 10.5 0.1 0.35 10.5 0.1 2.4 3 0 0 3 3 3 0 Insulin-induced protein (INSIG) PrgI PF12666.7 CEG45589.1 - 0.4 11.4 0.1 0.4 11.4 0.1 3.3 2 1 1 3 3 3 0 PrgI family protein UPF0060 PF02694.15 CEG45589.1 - 8 6.7 11.4 0.46 10.7 3.0 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Aminotran_5 PF00266.19 CEG45590.1 - 6.5e-28 97.7 0.0 1e-27 97.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEG45590.1 - 1.8e-07 30.8 0.2 3.1e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CEG45590.1 - 0.0028 16.3 0.1 0.0043 15.6 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TraI_2B PF18340.1 CEG45591.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain RD3 PF14473.6 CEG45592.1 - 0.073 12.9 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 RD3 protein Anti-adapt_IraP PF10796.9 CEG45592.1 - 0.43 11.2 9.0 13 6.4 0.2 4.3 4 2 1 5 5 5 0 Sigma-S stabilisation anti-adaptor protein CAP PF00188.26 CEG45594.1 - 4.4e-17 63.1 2.9 6.9e-17 62.5 2.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aa_trans PF01490.18 CEG45597.1 - 2e-25 89.4 0.2 7.8e-25 87.4 0.2 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Flp1_like PF16982.5 CEG45597.1 - 0.026 13.9 0.3 0.062 12.7 0.3 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF202 PF02656.15 CEG45597.1 - 0.13 12.7 0.4 0.13 12.7 0.4 3.2 5 0 0 5 5 5 0 Domain of unknown function (DUF202) Josephin PF02099.17 CEG45599.1 - 1.3e-09 38.4 0.0 1.4e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Josephin Aminotran_1_2 PF00155.21 CEG45603.1 - 3e-56 191.1 0.0 3.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG45603.1 - 0.11 11.4 0.0 0.75 8.7 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V Peptidase_S74 PF13884.6 CEG45605.1 - 4.9e-23 81.2 3.4 9.1e-11 41.9 0.2 2.3 2 0 0 2 2 2 2 Chaperone of endosialidase Ank_2 PF12796.7 CEG45609.1 - 8.1e-36 122.5 4.9 5.4e-12 46.1 0.0 6.6 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45609.1 - 1.9e-27 95.3 14.0 0.0016 18.9 0.0 9.7 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 CEG45609.1 - 1.9e-25 88.2 9.3 0.042 14.3 0.0 10.8 9 2 1 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 CEG45609.1 - 1.2e-24 86.0 4.1 0.0001 22.5 0.0 8.3 7 1 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG45609.1 - 1.8e-23 80.0 6.4 0.0027 18.1 0.0 10.3 11 1 0 11 11 11 5 Ankyrin repeat DUF4486 PF14858.6 CEG45611.1 - 6.5e-20 71.1 1.7 6.5e-20 71.1 1.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4486) fn3 PF00041.21 CEG45611.1 - 0.031 14.6 0.4 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Fibronectin type III domain Utp12 PF04003.12 CEG45611.1 - 0.13 12.6 3.0 0.29 11.5 0.1 3.2 2 0 0 2 2 2 0 Dip2/Utp12 Family GCP_C_terminal PF04130.13 CEG45612.1 - 5.7e-80 269.1 7.9 5.7e-80 269.1 7.9 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEG45612.1 - 5.3e-78 262.7 0.1 1.1e-77 261.7 0.1 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal KMP11 PF03037.16 CEG45612.1 - 0.2 12.5 1.5 0.88 10.4 1.5 2.1 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 DDHD PF02862.17 CEG45614.1 - 1.5e-28 100.5 5.1 1.6e-22 80.8 0.0 3.1 2 1 1 3 3 3 2 DDHD domain PX PF00787.24 CEG45614.1 - 1.4e-12 47.6 0.1 3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 PX domain PH PF00169.29 CEG45614.1 - 1.5e-05 25.4 2.0 0.0026 18.2 1.5 3.2 2 1 0 2 2 2 1 PH domain OTU PF02338.19 CEG45614.1 - 0.0069 16.9 0.1 0.029 14.9 0.1 2.1 1 0 0 1 1 1 1 OTU-like cysteine protease Cullin_binding PF03556.15 CEG45615.1 - 1.7e-34 118.8 1.7 1.7e-34 118.8 1.7 2.3 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 CEG45615.1 - 2.4e-09 36.8 0.1 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 CEG45615.1 - 0.025 14.2 0.2 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 TAP C-terminal domain DUF1892 PF08987.10 CEG45615.1 - 0.079 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) CCT PF06203.14 CEG45616.1 - 2.7e-09 36.9 6.2 4.5e-09 36.2 6.2 1.4 1 0 0 1 1 1 1 CCT motif EcoRII-C PF09019.11 CEG45617.1 - 0.0046 17.1 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 EcoRII C terminal Piwi PF02171.17 CEG45619.1 - 5.4e-95 318.1 0.0 7.4e-95 317.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CEG45619.1 - 2.7e-21 75.8 0.0 5.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CEG45619.1 - 1.9e-20 73.9 0.1 3.8e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CEG45619.1 - 9.4e-16 57.2 0.1 3.5e-15 55.4 0.1 2.1 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 CEG45619.1 - 3e-14 53.1 0.7 1.4e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 CEG45619.1 - 3.2e-11 43.4 0.0 8.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Es2 PF09751.9 CEG45621.1 - 0.018 14.8 6.1 0.036 13.8 6.1 1.4 1 0 0 1 1 1 0 Nuclear protein Es2 Serglycin PF04360.12 CEG45621.1 - 0.019 14.9 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Serglycin FAP PF07174.11 CEG45621.1 - 1.3 8.4 21.6 0.052 13.0 15.7 1.7 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) MCPVI PF02993.14 CEG45621.1 - 1.7 8.4 8.2 2.3 8.0 7.5 1.6 1 1 0 1 1 1 0 Minor capsid protein VI Auxin_repressed PF05564.12 CEG45621.1 - 3 8.5 28.7 5.8e+02 1.2 0.1 3.7 2 1 0 3 3 3 0 Dormancy/auxin associated protein zf-trcl PF13451.6 CEG45623.1 - 0.28 11.1 4.1 0.2 11.5 2.3 1.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain Peptidase_S8 PF00082.22 CEG45627.1 - 8.2e-81 271.5 1.0 1.2e-80 271.0 1.0 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 CEG45627.1 - 4.6e-42 143.7 3.1 3e-27 95.3 0.1 2.4 1 1 1 2 2 2 2 Tripeptidyl peptidase II PdxA PF04166.12 CEG45627.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA DegQ PF08181.11 CEG45627.1 - 0.09 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 DegQ (SacQ) family Lactonase PF10282.9 CEG45628.1 - 4e-95 319.0 0.1 4.5e-95 318.8 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 CEG45628.1 - 0.11 12.1 0.1 2.9 7.4 0.0 2.7 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Polyketide_cyc PF03364.20 CEG45629.1 - 9.5e-21 74.4 0.1 2e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EF-hand_1 PF00036.32 CEG45629.1 - 6.3e-08 31.6 4.5 0.0053 16.2 0.0 4.0 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 CEG45629.1 - 2e-06 27.3 0.2 0.0039 17.0 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CEG45629.1 - 9.6e-06 26.0 3.7 0.0012 19.2 0.9 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CEG45629.1 - 0.00024 20.9 0.2 0.016 15.0 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG45629.1 - 0.0083 15.6 6.2 0.14 11.7 0.0 3.9 5 0 0 5 5 5 1 EF hand DUF2000 PF09391.10 CEG45629.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Lactonase PF10282.9 CEG45631.1 - 1.7e-83 280.7 0.1 2e-83 280.5 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 CEG45631.1 - 0.016 14.8 0.2 2.2 7.8 0.0 2.6 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SBP56 PF05694.11 CEG45631.1 - 0.018 13.8 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Arylesterase PF01731.20 CEG45631.1 - 0.14 12.4 0.7 10 6.4 0.1 3.1 3 0 0 3 3 3 0 Arylesterase 2OG-FeII_Oxy_3 PF13640.6 CEG45633.1 - 1.1e-08 35.9 0.0 0.0005 20.9 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CEG45633.1 - 0.13 12.8 0.1 2.2 8.8 0.0 2.6 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily Sld5 PF05916.11 CEG45634.1 - 4.4e-05 23.9 0.5 0.00029 21.3 0.3 2.4 2 1 0 2 2 2 1 GINS complex protein SLD5_C PF16922.5 CEG45634.1 - 0.038 14.2 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Ank_2 PF12796.7 CEG45635.1 - 5.8e-20 71.7 0.9 4.6e-14 52.8 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG45635.1 - 8.6e-17 59.5 0.2 0.00056 20.2 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CEG45635.1 - 2.8e-13 49.7 4.6 0.001 19.4 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CEG45635.1 - 4e-13 49.6 1.2 2.1e-05 25.0 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG45635.1 - 9.9e-10 38.5 1.6 5.1e-05 23.5 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 CEG45635.1 - 1.1e-08 34.7 0.3 4.4e-07 29.6 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CEG45635.1 - 1.2e-08 35.3 0.0 3.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG45635.1 - 2.1e-08 33.1 0.2 0.0025 17.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG45635.1 - 5.8e-07 28.9 0.1 0.02 14.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG45635.1 - 0.00018 20.8 0.3 0.25 10.9 0.1 2.7 2 0 0 2 2 2 2 EF hand Gly_rich PF12810.7 CEG45635.1 - 0.02 14.8 48.7 0.023 14.6 47.5 1.6 1 1 0 1 1 1 0 Glycine rich protein zf-TRAF PF02176.18 CEG45635.1 - 0.29 11.8 19.8 0.18 12.5 3.6 3.7 2 1 1 3 3 3 0 TRAF-type zinc finger WW PF00397.26 CEG45635.1 - 3.1 7.9 13.8 1.8 8.7 4.2 3.3 4 0 0 4 4 3 0 WW domain Mt_ATP-synt_B PF05405.14 CEG45636.1 - 2.6e-24 85.7 1.8 2.6e-24 85.7 1.8 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_F6 PF05511.11 CEG45636.1 - 0.081 13.3 0.7 0.24 11.8 0.2 1.9 1 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DPRP PF04244.13 CEG45636.1 - 0.26 11.1 6.0 0.54 10.1 0.1 2.1 1 1 1 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein Jacalin PF01419.17 CEG45637.1 - 5.7e-39 133.1 12.1 2.2e-09 37.4 0.2 4.5 4 0 0 4 4 4 4 Jacalin-like lectin domain DUF4399 PF14347.6 CEG45637.1 - 0.1 13.0 0.5 21 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) Metallophos PF00149.28 CEG45638.1 - 8.7e-18 65.6 1.1 1.2e-17 65.1 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG45638.1 - 0.00026 21.2 6.7 0.0074 16.5 6.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Inh PF02974.14 CEG45650.1 - 0.092 12.8 3.1 0.59 10.2 1.5 2.1 1 1 1 2 2 2 0 Protease inhibitor Inh Cir_Bir_Yir PF06022.11 CEG45651.1 - 0.012 15.1 0.2 0.014 14.9 0.2 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir IBN_N PF03810.19 CEG45652.1 - 0.0006 19.7 7.4 0.0032 17.3 4.8 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain COPIIcoated_ERV PF07970.12 CEG45653.1 - 2.9e-68 230.0 0.1 8.7e-68 228.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Ion_trans PF00520.31 CEG45654.1 - 0.04 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein CBM_X2 PF03442.14 CEG45654.1 - 0.13 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Pkinase PF00069.25 CEG45655.1 - 5.1e-05 22.8 0.1 0.0053 16.2 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CEG45655.1 - 8.7e-05 22.6 0.1 0.13 12.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG45655.1 - 0.013 14.3 0.0 0.035 12.9 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 CEG45655.1 - 0.022 14.4 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_14 PF17959.1 CEG45655.1 - 0.026 14.9 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain APH PF01636.23 CEG45656.1 - 8.6e-05 22.6 0.1 0.02 14.8 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG45656.1 - 0.0031 16.3 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_14 PF17959.1 CEG45656.1 - 0.01 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain SRP_SPB PF02978.19 CEG45656.1 - 0.048 14.3 0.0 0.07 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal peptide binding domain Pkinase PF00069.25 CEG45656.1 - 0.24 10.7 0.0 0.73 9.1 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain Complex1_LYR PF05347.15 CEG45662.1 - 3.1e-12 46.3 4.3 3.9e-12 46.0 4.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEG45662.1 - 7e-07 29.9 1.7 8.1e-07 29.7 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CEG45662.1 - 0.00026 21.5 0.7 0.00031 21.3 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like YCII PF03795.14 CEG45663.1 - 2.4e-08 34.2 0.0 3.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Peptidase_S10 PF00450.22 CEG45664.1 - 1.8e-86 291.2 0.0 2.6e-86 290.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase RNase_PH PF01138.21 CEG45664.1 - 2.3e-23 83.1 0.3 4.1e-23 82.3 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEG45664.1 - 5.7e-06 26.3 0.2 3.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Pkinase_Tyr PF07714.17 CEG45666.1 - 1.3e-12 47.6 0.0 7.7e-12 45.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase STIMATE PF12400.8 CEG45667.1 - 1.2e-34 119.6 4.6 1.2e-34 119.6 4.6 1.7 2 0 0 2 2 2 1 STIMATE family UMPH-1 PF05822.12 CEG45668.1 - 1.8e-63 214.3 2.3 2.7e-61 207.2 2.3 2.1 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) CSN8_PSD8_EIF3K PF10075.9 CEG45669.1 - 1e-23 83.9 0.1 1.8e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CEG45669.1 - 2.1e-07 30.6 0.8 2.8e-07 30.2 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP family Chromo PF00385.24 CEG45670.1 - 1.8e-06 27.7 0.1 6.6e-06 25.9 0.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S26 PF10502.9 CEG45671.1 - 3.2e-08 33.5 0.1 1.1e-05 25.3 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 ELMO_CED12 PF04727.13 CEG45672.1 - 1.8e-26 93.3 0.0 4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family TRAPPC9-Trs120 PF08626.11 CEG45673.1 - 3.6e-36 124.0 0.1 3.2e-17 61.3 0.0 4.2 4 0 0 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CCDC24 PF15669.5 CEG45673.1 - 1.8e-17 63.9 0.0 1.8e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family CRF PF00473.17 CEG45673.1 - 0.0056 16.7 0.4 0.82 9.8 0.2 2.7 2 0 0 2 2 2 2 Corticotropin-releasing factor family DEAD PF00270.29 CEG45674.1 - 1.6e-41 142.0 0.0 6.4e-41 140.0 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG45674.1 - 1e-29 103.1 0.0 2.9e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG45674.1 - 0.00051 20.1 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 CEG45674.1 - 0.0033 17.4 1.6 0.0033 17.4 1.6 1.9 2 0 0 2 2 2 1 Zinc knuckle SecA_DEAD PF07517.14 CEG45674.1 - 0.021 14.2 0.7 0.067 12.5 0.7 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain GreA_GreB_N PF03449.15 CEG45674.1 - 0.082 13.1 5.0 0.26 11.4 5.0 1.9 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal TBX PF12598.8 CEG45674.1 - 0.15 12.9 4.2 0.32 11.8 4.2 1.5 1 0 0 1 1 1 0 T-box transcription factor DUF4256 PF14066.6 CEG45674.1 - 0.55 9.9 3.3 1.1 8.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Arf PF00025.21 CEG45675.1 - 3.4e-57 192.7 0.0 4.2e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CEG45675.1 - 1.1e-11 44.5 0.2 7.7e-08 31.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CEG45675.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEG45675.1 - 3.8e-11 42.8 0.0 4.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEG45675.1 - 3.2e-10 39.8 0.0 3.6e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEG45675.1 - 4.2e-09 36.1 0.0 5.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 CEG45675.1 - 0.00033 20.3 0.2 0.47 10.0 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CEG45675.1 - 0.00047 20.2 0.0 0.00091 19.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG45675.1 - 0.00055 19.9 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CEG45675.1 - 0.0033 17.3 0.4 0.97 9.3 0.0 2.1 2 0 0 2 2 2 2 NACHT domain MobB PF03205.14 CEG45675.1 - 0.0036 17.2 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 CEG45675.1 - 0.016 14.2 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CEG45675.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Apyrase PF06079.11 CEG45676.1 - 8.1e-96 320.7 2.4 9.4e-64 215.4 0.2 2.1 1 1 1 2 2 2 2 Apyrase AlgF PF11182.8 CEG45676.1 - 0.034 14.0 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Ribosomal_60s PF00428.19 CEG45677.1 - 1.7e-17 63.7 12.1 3.1e-17 62.9 12.1 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DHHC PF01529.20 CEG45677.1 - 2.7e-11 43.7 1.8 2.7e-11 43.7 1.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DASH_Dad2 PF08654.10 CEG45677.1 - 5.7e-08 33.1 1.1 1.2e-07 32.1 1.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 Xpo1 PF08389.12 CEG45677.1 - 0.033 14.2 0.5 0.094 12.8 0.5 1.8 1 0 0 1 1 1 0 Exportin 1-like protein DUF4030 PF13222.6 CEG45677.1 - 0.23 11.6 1.9 0.25 11.5 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4030) CHD5 PF04420.14 CEG45678.1 - 1.7e-13 50.7 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 CHD5-like protein Efg1 PF10153.9 CEG45678.1 - 0.0016 18.8 0.2 0.0021 18.4 0.2 1.1 1 0 0 1 1 1 1 rRNA-processing protein Efg1 DUF2207 PF09972.9 CEG45678.1 - 0.0053 15.6 0.0 0.0064 15.3 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2730 PF10805.8 CEG45678.1 - 0.035 14.2 0.7 0.052 13.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) RF3_C PF16658.5 CEG45678.1 - 0.07 13.0 0.3 0.099 12.5 0.3 1.2 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DASH_Dad3 PF08656.10 CEG45678.1 - 0.18 11.9 2.3 0.6 10.2 2.3 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 Ubiquitin_2 PF14560.6 CEG45679.1 - 2.2e-25 88.9 0.1 3.6e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CEG45679.1 - 6.6e-22 77.3 2.4 1.1e-21 76.6 2.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CEG45679.1 - 0.056 13.2 0.0 0.57 10.0 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin family ENTH PF01417.20 CEG45682.1 - 9e-12 45.1 0.1 1.9e-11 44.1 0.0 1.6 2 1 0 2 2 2 1 ENTH domain TPR_2 PF07719.17 CEG45683.1 - 2.4e-11 42.8 4.4 4.1e-05 23.4 0.0 5.8 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG45683.1 - 5.8e-11 41.7 5.3 0.00011 21.8 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45683.1 - 1e-06 28.5 3.5 0.028 14.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG45683.1 - 4.7e-06 26.2 0.0 0.012 15.3 0.0 3.8 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 CEG45683.1 - 4e-05 23.8 6.2 0.0067 16.7 0.5 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45683.1 - 0.00038 20.3 1.4 0.11 12.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG45683.1 - 0.0014 18.8 0.4 0.017 15.5 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45683.1 - 0.0026 18.2 8.7 0.014 15.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG45683.1 - 0.0078 16.8 4.6 5 8.0 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45683.1 - 0.03 15.1 8.0 1.7 9.7 0.0 4.1 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEG45683.1 - 0.33 11.1 5.1 3 8.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S46 PF10459.9 CEG45683.1 - 0.6 8.7 14.9 0.88 8.1 14.9 1.2 1 0 0 1 1 1 0 Peptidase S46 Nrap_D3 PF17404.2 CEG45684.1 - 6.6e-41 140.0 0.0 1.4e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 CEG45684.1 - 2.5e-39 134.9 0.0 4.7e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 CEG45684.1 - 5.5e-35 120.6 0.0 1.4e-34 119.4 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D5 PF17406.2 CEG45684.1 - 1.1e-34 119.6 2.7 7.5e-34 116.8 0.3 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 CEG45684.1 - 2.5e-31 108.5 0.8 2.5e-31 108.5 0.8 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 CEG45684.1 - 1.2e-23 83.8 0.0 2.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Dynein_light PF01221.18 CEG45688.1 - 9.8e-26 89.9 0.5 1.1e-25 89.7 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TetR_C_10 PF16295.5 CEG45688.1 - 0.049 13.9 0.1 0.061 13.6 0.1 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_43 PF09904.9 CEG45689.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix FGE-sulfatase PF03781.16 CEG45691.1 - 5.2e-23 81.9 0.1 7.9e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CEG45691.1 - 1.3e-07 32.2 1.1 2.2e-07 31.4 1.1 1.4 1 0 0 1 1 1 1 DinB superfamily Sel1 PF08238.12 CEG45692.1 - 2.1e-14 53.6 0.3 0.0045 17.6 0.0 4.5 4 0 0 4 4 4 4 Sel1 repeat DUF4559 PF15112.6 CEG45692.1 - 0.036 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TPR_8 PF13181.6 CEG45692.1 - 0.85 10.0 5.6 7 7.1 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Dzip-like_N PF13815.6 CEG45693.1 - 5.2e-10 39.3 0.5 5.2e-10 39.3 0.5 4.6 3 2 2 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 CEG45693.1 - 0.0031 17.9 0.3 0.015 15.7 0.3 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-BED PF02892.15 CEG45693.1 - 0.014 15.4 1.8 0.022 14.8 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger Coat_F PF07875.12 CEG45693.1 - 0.12 12.7 0.9 0.55 10.5 0.1 2.6 2 0 0 2 2 2 0 Coat F domain Cation_ATPase PF13246.6 CEG45693.1 - 0.21 11.7 1.8 0.72 10.0 1.8 1.9 1 0 0 1 1 1 0 Cation transport ATPase (P-type) LMBR1 PF04791.16 CEG45693.1 - 4 6.2 20.6 2.3 7.0 5.2 2.5 1 1 1 2 2 2 0 LMBR1-like membrane protein Ribonuc_L-PSP PF01042.21 CEG45693.1 - 7.8 6.5 8.1 0.18 11.8 0.2 2.4 3 0 0 3 3 3 0 Endoribonuclease L-PSP Rad51 PF08423.11 CEG45694.1 - 2.6e-28 99.0 0.3 4.5e-28 98.2 0.3 1.4 1 0 0 1 1 1 1 Rad51 NUC153 PF08159.12 CEG45694.1 - 1.5e-10 40.7 1.7 4.4e-10 39.2 1.7 1.9 1 0 0 1 1 1 1 NUC153 domain DnaB_C PF03796.15 CEG45694.1 - 2.8e-08 33.4 0.2 6.2e-08 32.3 0.2 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ANAPC4_WD40 PF12894.7 CEG45694.1 - 0.00012 22.3 0.0 1.4 9.2 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ATPase PF06745.13 CEG45694.1 - 0.0038 16.6 0.1 0.0079 15.6 0.1 1.6 1 0 0 1 1 1 1 KaiC SCAB-ABD PF16711.5 CEG45694.1 - 0.076 12.9 0.2 0.31 11.0 0.2 2.1 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein RIO1 PF01163.22 CEG45695.1 - 0.022 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CEG45695.1 - 0.055 13.4 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 CEG45695.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EF-hand_14 PF17959.1 CEG45695.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain HOCHOB PF17943.1 CEG45699.1 - 0.042 14.6 0.0 0.092 13.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox SpoIIID PF12116.8 CEG45700.1 - 0.0027 17.7 0.7 0.031 14.4 0.0 3.1 2 2 0 2 2 2 1 Stage III sporulation protein D DUF3666 PF12408.8 CEG45700.1 - 0.046 12.9 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase DUF2576 PF10845.8 CEG45700.1 - 0.068 12.8 0.2 0.22 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Bac_small_YrzI PF09501.10 CEG45700.1 - 0.079 13.1 2.2 0.19 11.9 0.1 2.7 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) FGE-sulfatase PF03781.16 CEG45701.1 - 4e-27 95.4 0.2 7.5e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF3786 PF12654.7 CEG45701.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RWP-RK PF02042.15 CEG45702.1 - 6.7e-20 70.8 0.2 1.2e-19 70.0 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 CEG45702.1 - 1.1e-11 44.8 0.1 2.9e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG45702.1 - 0.0075 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG45702.1 - 0.027 14.3 0.3 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like COX5B PF01215.19 CEG45703.1 - 1.6e-15 56.9 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb HTH_Tnp_Tc5 PF03221.16 CEG45704.1 - 5.2e-11 42.4 0.0 8.3e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEG45704.1 - 0.00014 21.5 0.2 0.00014 21.5 0.2 1.7 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CEG45704.1 - 0.0032 18.1 1.7 0.0051 17.4 0.2 2.2 3 0 0 3 3 3 1 Homeodomain-like domain zf-MYND PF01753.18 CEG45705.1 - 8.2e-10 38.6 10.9 1.5e-09 37.8 10.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CEG45705.1 - 0.0011 19.3 11.6 0.002 18.4 11.6 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF3846 PF12957.7 CEG45705.1 - 0.0086 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) zf-HIT PF04438.16 CEG45705.1 - 0.082 12.8 9.2 0.15 12.0 9.2 1.4 1 0 0 1 1 1 0 HIT zinc finger HECT PF00632.25 CEG45708.1 - 4.3e-60 203.8 0.6 7.2e-60 203.0 0.6 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 CEG45708.1 - 0.049 13.0 0.5 0.12 11.7 0.5 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others 60KD_IMP PF02096.20 CEG45709.1 - 5.3e-35 120.8 1.6 1e-34 119.9 1.6 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Glyco_transf_8C PF08437.10 CEG45709.1 - 0.016 15.3 0.5 0.048 13.7 0.2 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal APG17 PF04108.12 CEG45710.1 - 2.2e-30 106.1 12.0 1.2e-21 77.3 1.1 2.1 1 1 1 2 2 2 2 Autophagy protein Apg17 TcpF PF06340.11 CEG45710.1 - 0.1 11.5 0.1 0.19 10.5 0.1 1.5 2 0 0 2 2 2 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F RhoGEF PF00621.20 CEG45710.1 - 0.31 11.3 12.2 0.26 11.5 6.5 2.2 1 1 1 2 2 2 0 RhoGEF domain HECT PF00632.25 CEG45711.1 - 4.6e-67 226.7 0.0 6.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Zn_ribbon_recom PF13408.6 CEG45711.1 - 0.2 12.2 0.4 0.52 10.9 0.4 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_L27e PF01777.18 CEG45711.1 - 0.27 11.6 0.0 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L27e protein family TH1 PF04858.13 CEG45712.1 - 4.6e-87 293.0 3.0 6.4e-87 292.6 3.0 1.1 1 0 0 1 1 1 1 TH1 protein WW PF00397.26 CEG45712.1 - 2e-17 62.9 16.2 6.2e-09 35.8 2.9 2.6 2 0 0 2 2 2 2 WW domain Nucleo_P87 PF07267.11 CEG45712.1 - 0.077 11.8 11.2 0.12 11.2 11.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Aha1_N PF09229.11 CEG45713.1 - 9.7e-25 87.4 0.7 1.2e-24 87.1 0.7 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Pro_Al_protease PF02983.14 CEG45714.1 - 1.1 9.4 3.5 8.1 6.6 0.2 3.7 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Transketolase_N PF00456.21 CEG45715.1 - 2.5e-150 500.1 0.0 4.4e-150 499.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CEG45715.1 - 3.4e-41 140.9 0.1 5.8e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEG45715.1 - 6.7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CEG45715.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase VirK PF06903.12 CEG45715.1 - 0.14 12.3 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 VirK protein Terpene_synth PF01397.21 CEG45715.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain CYYR1 PF10873.8 CEG45715.1 - 0.25 11.8 1.6 0.67 10.4 0.3 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 CGI-121 PF08617.10 CEG45718.1 - 1.2e-37 129.5 0.1 1.4e-37 129.3 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TPR_1 PF00515.28 CEG45719.1 - 3.1e-19 67.9 0.0 0.0001 22.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CEG45719.1 - 6.4e-18 65.1 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 CEG45719.1 - 3.1e-11 42.5 0.0 0.0031 17.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45719.1 - 3.9e-09 36.0 0.0 0.077 13.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG45719.1 - 1.7e-07 30.8 0.1 0.00014 21.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CEG45719.1 - 2.6e-06 27.9 0.0 0.00042 20.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG45719.1 - 8.7e-05 22.6 2.2 0.002 18.3 0.2 3.8 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEG45719.1 - 0.0001 22.8 0.2 0.0005 20.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45719.1 - 0.00022 21.0 0.3 0.53 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG45719.1 - 0.0003 20.9 0.5 0.23 11.6 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45719.1 - 0.004 17.4 2.2 0.54 10.6 1.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEG45719.1 - 0.037 14.7 1.2 15 6.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45719.1 - 0.057 14.3 0.0 26 6.0 0.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG45719.1 - 0.067 13.3 0.2 4.9 7.3 0.1 2.8 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MULE PF10551.9 CEG45720.1 - 2.6e-06 27.7 0.0 5.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 CEG45720.1 - 0.00059 19.8 0.9 0.0017 18.3 0.1 2.1 2 0 0 2 2 2 1 MuDR family transposase Copper-fist PF00649.18 CEG45720.1 - 0.1 12.1 0.2 0.25 10.8 0.2 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain AT_hook PF02178.19 CEG45720.1 - 0.11 12.4 0.6 0.31 11.1 0.6 1.8 1 0 0 1 1 1 0 AT hook motif ABC_ATPase PF09818.9 CEG45721.1 - 8e-172 572.0 0.0 9.7e-172 571.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CEG45721.1 - 0.013 16.0 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEG45721.1 - 0.17 11.7 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pro_dh PF01619.18 CEG45722.1 - 8.6e-80 268.4 0.2 4.5e-79 266.1 0.2 1.9 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_6 PF13405.6 CEG45722.1 - 0.008 16.0 0.1 0.041 13.8 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CEG45722.1 - 0.025 15.0 0.0 0.1 13.1 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair Phasin_2 PF09361.10 CEG45722.1 - 0.043 14.1 2.6 0.36 11.1 0.1 3.0 3 0 0 3 3 3 0 Phasin protein WHEP-TRS PF00458.20 CEG45723.1 - 5.6e-10 39.2 4.8 1.7e-09 37.7 4.8 1.8 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CEG45723.1 - 3.7e-09 36.8 0.1 1.6e-08 34.8 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BCDHK_Adom3 PF10436.9 CEG45724.1 - 1.1e-27 96.8 0.0 1.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Glyco_hydro_81 PF03639.13 CEG45725.1 - 1.8e-08 33.9 0.1 2.4e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain RXLR PF16810.5 CEG45727.1 - 0.00042 20.8 0.0 0.00048 20.6 0.0 1.1 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity NB PF04159.13 CEG45727.1 - 0.065 13.3 0.4 0.14 12.2 0.2 1.6 2 0 0 2 2 2 0 NB glycoprotein DUF2909 PF11137.8 CEG45728.1 - 0.059 13.3 2.4 0.097 12.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) NPR2 PF06218.11 CEG45729.1 - 3e-87 293.2 4.0 5.8e-69 232.9 2.9 3.6 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF3172 PF11371.8 CEG45729.1 - 0.047 13.4 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) HECT PF00632.25 CEG45730.1 - 5.5e-72 242.9 0.0 7.5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 CEG45730.1 - 9.2e-05 21.7 0.8 0.00021 20.5 0.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others NigD_C PF17415.2 CEG45730.1 - 0.085 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 NigD-like C-terminal beta sandwich domain DZR PF12773.7 CEG45730.1 - 0.09 12.8 0.7 0.16 12.0 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Virul_fac_BrkB PF03631.15 CEG45732.1 - 0.069 12.7 10.1 0.098 12.2 10.1 1.3 1 0 0 1 1 1 0 Virulence factor BrkB T2SSG PF08334.11 CEG45734.1 - 0.24 11.5 4.7 2.9 8.0 0.3 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G DUF4188 PF13826.6 CEG45734.1 - 1.3 9.3 4.4 1.4 9.2 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) TPR_1 PF00515.28 CEG45736.1 - 1.8e-09 37.0 2.3 0.0012 18.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG45736.1 - 2e-08 33.7 4.3 0.0065 16.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG45736.1 - 0.00012 22.3 1.9 0.017 15.4 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat cNMP_binding PF00027.29 CEG45736.1 - 0.00016 21.7 0.3 0.018 15.1 0.0 3.7 4 0 0 4 4 4 1 Cyclic nucleotide-binding domain TPR_9 PF13371.6 CEG45736.1 - 0.002 18.2 0.5 0.057 13.6 0.1 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG45736.1 - 0.011 15.9 1.6 2.5 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45736.1 - 0.034 14.2 0.4 15 5.9 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG45736.1 - 0.18 11.5 0.4 30 4.4 0.0 3.3 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 CEG45736.1 - 0.19 12.7 3.9 70 4.6 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 CEG45737.1 - 3.2e-24 85.3 0.7 5.8e-13 49.2 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG45737.1 - 8.7e-17 61.3 0.4 3.1e-10 40.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG45737.1 - 3.5e-13 49.3 0.3 2.4e-05 24.6 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEG45737.1 - 3.1e-10 39.4 0.1 0.00046 20.4 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEG45737.1 - 0.00011 22.4 0.4 0.033 14.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RepB-RCR_reg PF10723.9 CEG45737.1 - 0.024 14.6 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB ATG101 PF07855.12 CEG45739.1 - 1.2e-36 126.0 0.0 1.5e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 zf-C3HC4_2 PF13923.6 CEG45741.1 - 1.6e-07 31.0 9.2 3.2e-07 30.1 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG45741.1 - 8.7e-06 25.5 9.7 1.6e-05 24.6 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEG45741.1 - 0.00013 21.7 2.9 0.00027 20.7 2.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CEG45741.1 - 0.00055 20.2 9.7 0.0011 19.3 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEG45741.1 - 0.0016 18.4 9.2 0.0028 17.6 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG45741.1 - 0.0025 17.8 7.8 0.0049 16.9 7.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEG45741.1 - 0.0052 16.6 7.5 0.012 15.4 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 CEG45741.1 - 0.0057 17.3 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_5 PF17121.5 CEG45741.1 - 0.012 15.5 3.5 0.027 14.3 3.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CEG45741.1 - 0.017 15.2 5.0 0.044 13.9 5.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DiS_P_DiS PF06750.13 CEG45741.1 - 0.043 13.9 4.0 0.047 13.8 2.4 1.9 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF1272 PF06906.11 CEG45741.1 - 0.15 12.2 3.1 0.31 11.2 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 CEG45741.1 - 0.22 11.7 8.7 0.41 10.8 8.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEG45741.1 - 2.1 8.3 12.1 0.9 9.5 8.8 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CEG45741.1 - 2.9 7.7 6.5 6.5 6.6 6.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF641 PF04859.12 CEG45742.1 - 0.095 13.0 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) RIH_assoc PF08454.11 CEG45743.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 RyR and IP3R Homology associated PRESAN PF09687.10 CEG45744.1 - 0.02 15.5 0.8 0.025 15.1 0.8 1.1 1 0 0 1 1 1 0 Plasmodium RESA N-terminal CdiI PF07262.11 CEG45744.1 - 0.045 13.5 0.2 0.061 13.1 0.2 1.1 1 0 0 1 1 1 0 CDI immunity protein Glyco_hydro_10 PF00331.20 CEG45746.1 - 6e-72 242.5 9.4 7.5e-72 242.1 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Phi29_Phage_SSB PF17427.2 CEG45746.1 - 0.054 13.7 0.8 0.53 10.5 0.1 2.6 2 1 1 3 3 3 0 Phage Single-stranded DNA-binding protein DUF2083 PF09856.9 CEG45746.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Dynamin_N PF00350.23 CEG45747.1 - 6.2e-11 42.6 0.0 1.1e-08 35.3 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CEG45747.1 - 4.9e-05 23.4 0.0 0.00023 21.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 CEG45747.1 - 0.001 19.6 0.1 0.044 14.4 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5600) FeoB_N PF02421.18 CEG45747.1 - 0.036 13.6 0.4 12 5.4 0.0 3.6 4 0 0 4 4 4 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG45747.1 - 0.095 12.6 0.0 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase DUF913 PF06025.12 CEG45747.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Roc PF08477.13 CEG45747.1 - 0.15 12.3 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BUD22 PF09073.10 CEG45748.1 - 1.7e-07 31.0 7.2 1.7e-07 31.0 7.2 2.3 1 1 1 2 2 2 1 BUD22 YbaB_DNA_bd PF02575.16 CEG45748.1 - 0.48 10.7 7.7 0.24 11.6 2.9 2.6 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family TPH PF13868.6 CEG45749.1 - 7.1e-33 113.6 97.3 7.1e-33 113.6 97.3 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain CDP-OH_P_transf PF01066.21 CEG45750.1 - 1.1e-14 55.0 0.1 3.3e-14 53.4 0.1 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Ery_res_leader1 PF08051.11 CEG45750.1 - 0.13 12.4 0.1 0.54 10.5 0.1 2.1 1 0 0 1 1 1 0 Erythromycin resistance leader peptide Rer1 PF03248.13 CEG45751.1 - 2.9e-63 212.7 8.2 4.7e-63 212.0 8.2 1.3 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 CEG45751.1 - 0.028 14.0 0.1 0.028 14.0 0.1 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) Lsr2 PF11774.8 CEG45751.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Lsr2 DnaJ PF00226.31 CEG45753.1 - 1.1e-12 47.8 0.2 1.1e-12 47.8 0.2 3.7 3 1 0 3 3 3 2 DnaJ domain FYVE_2 PF02318.16 CEG45754.1 - 4.3 7.6 13.6 1.9 8.7 10.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger IQ PF00612.27 CEG45755.1 - 0.00016 21.2 6.1 0.048 13.5 2.6 3.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF1414 PF07208.11 CEG45755.1 - 0.03 14.3 0.0 0.087 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) VPS13 PF16908.5 CEG45756.1 - 1.4e-43 149.4 0.5 1.4e-43 149.4 0.5 4.4 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CEG45756.1 - 9.3e-26 90.2 0.0 3.4e-25 88.4 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CEG45756.1 - 3.7e-12 46.2 0.0 7.8e-11 41.9 0.0 3.0 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CEG45756.1 - 5e-10 39.2 11.0 0.00011 21.7 0.2 4.9 4 1 0 4 4 4 3 Repeating coiled region of VPS13 PDZ_6 PF17820.1 CEG45756.1 - 3.5e-07 30.0 0.0 1.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CEG45756.1 - 1.2e-05 25.6 0.0 5.3e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 PDZ domain VPS13_C PF16909.5 CEG45756.1 - 2.6e-05 24.1 0.3 9.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal PDZ_2 PF13180.6 CEG45756.1 - 0.014 15.7 0.0 0.087 13.2 0.0 2.4 1 0 0 1 1 1 0 PDZ domain Tricorn_PDZ PF14685.6 CEG45756.1 - 0.088 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain AA_permease_2 PF13520.6 CEG45757.1 - 4.4e-22 78.5 23.0 1.7e-19 70.0 12.7 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CEG45757.1 - 9.2e-18 64.1 19.7 8.7e-16 57.6 19.7 2.1 1 1 0 1 1 1 1 Amino acid permease DDE_3 PF13358.6 CEG45758.1 - 0.00044 20.0 0.1 0.0018 18.1 0.1 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease Peptidase_C5 PF00770.18 CEG45759.1 - 0.031 14.0 0.0 0.04 13.6 0.0 1.4 1 1 0 1 1 1 0 Adenovirus endoprotease COX14 PF14880.6 CEG45759.1 - 0.064 13.1 2.1 0.064 13.1 2.1 1.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Tox-ART-HYE1 PF15634.6 CEG45759.1 - 0.13 11.6 0.5 4.1 6.6 0.0 2.0 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase RNA_replicase_B PF03431.13 CEG45761.1 - 0.062 11.7 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 RNA replicase, beta-chain Mucin PF01456.17 CEG45761.1 - 0.6 10.1 30.7 1.5 8.9 30.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SOG2 PF10428.9 CEG45761.1 - 1.4 8.0 12.2 1.9 7.6 12.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4015 PF13200.6 CEG45764.1 - 0.062 12.3 0.1 0.062 12.3 0.1 1.0 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain RRM_1 PF00076.22 CEG45776.1 - 4.1e-19 68.2 0.0 6.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_ABP1_N PF18107.1 CEG45776.1 - 0.055 13.2 0.5 0.13 12.0 0.5 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain VID27_N PF17748.1 CEG45776.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 VID27 N-terminal region RRM_5 PF13893.6 CEG45776.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG45776.1 - 0.15 12.0 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 CEG45776.1 - 0.25 11.6 0.5 0.34 11.2 0.0 1.5 2 0 0 2 2 2 0 RRM-like domain Filamin PF00630.19 CEG45777.1 - 1.1e-55 186.8 0.0 5.5e-12 46.4 0.0 8.7 10 0 0 10 10 10 6 Filamin/ABP280 repeat PA14 PF07691.12 CEG45777.1 - 4e-28 98.1 0.0 1.9e-11 44.0 0.0 3.6 3 0 0 3 3 3 3 PA14 domain Invasin_D3 PF09134.10 CEG45777.1 - 6.3e-12 45.6 12.5 0.0068 16.7 0.0 6.4 7 0 0 7 7 7 4 Invasin, domain 3 Calx-beta PF03160.14 CEG45777.1 - 7.2e-05 22.9 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 Calx-beta domain Neurexophilin PF06312.12 CEG45777.1 - 0.0003 20.3 3.3 0.76 9.2 0.0 3.5 3 0 0 3 3 3 2 Neurexophilin Laminin_EGF PF00053.24 CEG45777.1 - 0.0022 18.1 9.3 0.0022 18.1 9.3 2.4 3 0 0 3 3 3 1 Laminin EGF domain EGF_2 PF07974.13 CEG45777.1 - 0.97 9.9 8.2 2.5 8.5 8.2 1.7 1 0 0 1 1 1 0 EGF-like domain UbiA PF01040.18 CEG45780.1 - 0.0014 18.0 19.0 0.0022 17.3 18.8 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Adeno_E3_CR2 PF02439.15 CEG45780.1 - 8.4 6.2 9.9 0.19 11.5 2.5 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TPR_MLP1_2 PF07926.12 CEG45781.1 - 0.00043 20.3 7.0 0.00043 20.3 7.0 3.5 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 CEG45781.1 - 0.02 14.3 31.5 1.6 8.0 31.5 2.3 1 1 0 1 1 1 0 Rabaptin-like protein OmpH PF03938.14 CEG45781.1 - 0.37 11.1 21.2 0.081 13.3 5.6 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 CEG45781.1 - 0.77 9.4 38.8 0.12 12.0 9.3 3.7 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease WXG100 PF06013.12 CEG45781.1 - 0.99 9.7 8.8 2.1 8.7 1.6 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG FapA PF03961.13 CEG45781.1 - 3.9 6.0 16.5 0.17 10.5 3.2 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 CEG45781.1 - 5.3 7.1 14.4 1.4 8.9 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) IFP_35_N PF07334.13 CEG45781.1 - 8 6.6 16.1 0.74 9.9 1.6 4.4 4 0 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SHE3 PF17078.5 CEG45781.1 - 9.3 5.9 29.0 0.46 10.2 4.6 3.1 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 CobT PF06213.12 CEG45783.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Exonuc_V_gamma PF04257.14 CEG45784.1 - 0.009 14.3 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit Tn7_Tnp_TnsA_C PF08721.11 CEG45784.1 - 0.056 14.1 0.2 0.51 11.0 0.2 2.3 1 1 1 2 2 2 0 TnsA endonuclease C terminal ENTH PF01417.20 CEG45785.1 - 0.0058 16.7 0.5 0.042 13.9 0.0 2.1 2 0 0 2 2 2 1 ENTH domain HEAT PF02985.22 CEG45785.1 - 0.075 13.3 0.2 8 7.0 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat TFIIA PF03153.13 CEG45785.1 - 1.5 8.7 25.2 0.54 10.2 22.1 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prenyltrans PF00432.21 CEG45787.1 - 1.2e-33 114.5 14.0 1.6e-11 43.8 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat FA_desaturase PF00487.24 CEG45790.1 - 9.8e-26 91.1 18.4 1.4e-25 90.6 18.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CEG45790.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Peptidase_M60 PF13402.6 CEG45790.1 - 0.079 12.5 0.5 0.15 11.5 0.5 1.5 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like RRM_1 PF00076.22 CEG45791.1 - 1e-64 214.2 14.0 2.8e-19 68.7 0.2 7.5 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG45791.1 - 9.7e-10 38.2 0.3 0.0038 17.1 0.2 4.5 4 1 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CEG45791.1 - 7.3e-05 22.4 3.7 0.62 9.7 0.0 4.3 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CEG45791.1 - 0.0018 18.1 2.2 0.096 12.5 0.0 3.9 4 1 1 5 5 5 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CEG45791.1 - 0.0036 17.4 2.4 0.46 10.6 0.0 4.6 5 0 0 5 5 5 1 RNA recognition motif G-patch PF01585.23 CEG45792.1 - 7e-14 51.4 0.5 7e-14 51.4 0.5 2.2 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 CEG45792.1 - 2.8e-07 30.5 0.2 2.8e-07 30.5 0.2 2.7 2 1 0 2 2 1 1 G-patch domain CDC45 PF02724.14 CEG45792.1 - 0.00064 18.2 2.8 0.00064 18.2 2.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Coilin_N PF15862.5 CEG45792.1 - 0.015 15.1 8.3 0.023 14.5 8.3 1.4 1 0 0 1 1 1 0 Coilin N-terminus Pox_P4B PF03292.14 CEG45792.1 - 0.049 11.9 4.7 0.067 11.5 4.7 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF1764 PF08576.10 CEG45792.1 - 0.062 14.2 12.0 0.11 13.4 12.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RR_TM4-6 PF06459.12 CEG45792.1 - 0.12 12.2 7.5 0.15 11.8 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 CEG45792.1 - 0.38 8.9 14.7 0.48 8.6 14.7 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Cellulose_synt PF03552.14 CEG45792.1 - 1 7.8 4.1 1.2 7.5 4.1 1.1 1 0 0 1 1 1 0 Cellulose synthase RNA_polI_A34 PF08208.11 CEG45792.1 - 4.3 7.4 21.7 5.8 7.0 21.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Dsh_C PF12316.8 CEG45792.1 - 7 7.0 7.8 11 6.4 7.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 CEG45792.1 - 7.2 5.3 6.4 9.2 4.9 6.4 1.1 1 0 0 1 1 1 0 Presenilin Arm PF00514.23 CEG45793.1 - 0.0016 18.4 1.3 9.2 6.5 0.0 4.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG45793.1 - 0.002 18.6 6.6 6.9 7.3 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat S_layer_N PF05123.12 CEG45793.1 - 0.011 15.6 5.6 0.021 14.7 5.6 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region HEAT PF02985.22 CEG45793.1 - 2.5 8.6 6.0 16 6.1 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat EF-hand_6 PF13405.6 CEG45795.1 - 0.0054 16.6 0.0 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CEG45795.1 - 0.0098 16.3 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ins145_P3_rec PF08709.11 CEG45795.1 - 0.059 12.6 0.7 3.1 7.0 0.0 3.4 3 2 2 5 5 5 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Aminotran_1_2 PF00155.21 CEG45796.1 - 1.1e-66 225.5 0.0 1.3e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEG45796.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CEG45796.1 - 4e-05 22.7 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEG45796.1 - 0.00051 18.7 0.0 0.00078 18.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 CEG45796.1 - 0.00069 18.3 0.0 0.002 16.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_3 PF00202.21 CEG45796.1 - 0.0024 16.6 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 CEG45796.1 - 0.012 15.0 0.1 0.024 14.0 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Flg_hook PF02120.16 CEG45796.1 - 0.11 12.3 0.0 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Sigma70_r2 PF04542.14 CEG45796.1 - 0.18 11.6 0.6 0.76 9.6 0.1 2.3 2 0 0 2 2 2 0 Sigma-70 region 2 H_PPase PF03030.16 CEG45798.1 - 9.4e-255 847.2 32.7 1.2e-254 846.9 32.7 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Acyl-CoA_dh_1 PF00441.24 CEG45799.1 - 2.9e-44 150.9 1.1 5e-44 150.1 0.6 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG45799.1 - 1.2e-28 100.0 0.0 5e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEG45799.1 - 1.6e-23 82.7 0.0 2.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG45799.1 - 1.7e-18 67.1 0.0 1.5e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 CEG45800.1 - 1e-58 198.8 0.0 4.3e-51 173.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45800.1 - 9.4e-34 116.9 0.0 1e-31 110.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG45800.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CEG45800.1 - 0.12 11.4 0.1 0.33 10.0 0.1 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_16 PF10294.9 CEG45801.1 - 9e-17 61.4 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG45801.1 - 0.035 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG45801.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SDA1 PF05285.12 CEG45802.1 - 2.9e-46 158.5 26.9 9e-30 104.3 1.7 3.0 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 CEG45802.1 - 2.2e-19 69.5 0.9 6.3e-19 68.0 0.1 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Sugar_tr PF00083.24 CEG45803.1 - 1.9e-117 392.9 23.0 4.6e-117 391.6 23.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG45803.1 - 2.2e-19 69.6 34.1 2.2e-19 69.6 34.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Med22 PF06179.12 CEG45806.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex HSP70 PF00012.20 CEG45807.1 - 2.4e-228 759.2 8.8 2.4e-228 759.2 8.8 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEG45807.1 - 6.3e-16 58.1 0.2 1.5e-14 53.6 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein TPR_2 PF07719.17 CEG45807.1 - 4.3e-10 38.9 2.2 0.0015 18.5 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG45807.1 - 8.6e-10 38.0 1.4 0.00013 21.6 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG45807.1 - 3.6e-07 29.8 4.8 2.4e-05 23.9 0.1 3.4 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 CEG45807.1 - 2.6e-06 27.2 2.8 0.27 11.5 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG45807.1 - 4e-05 23.3 0.2 0.079 13.0 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG45807.1 - 0.00081 19.6 0.8 0.2 12.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat FtsA PF14450.6 CEG45807.1 - 0.0017 18.8 0.1 1 9.8 0.0 3.2 2 0 0 2 2 2 1 Cell division protein FtsA TPR_19 PF14559.6 CEG45807.1 - 0.003 18.0 1.9 3.4 8.3 0.5 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG45807.1 - 0.0032 18.1 3.1 0.057 14.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG45807.1 - 0.018 15.8 5.9 15 6.7 0.0 5.1 3 1 2 5 5 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 CEG45807.1 - 0.14 12.8 2.3 3.4 8.4 0.0 3.5 3 0 0 3 3 2 0 von Willebrand factor type A domain TPR_12 PF13424.6 CEG45807.1 - 0.84 10.0 5.6 14 6.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Hexapep PF00132.24 CEG45808.1 - 0.075 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Pkinase_Tyr PF07714.17 CEG45809.1 - 2.3e-22 79.5 0.0 3.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG45809.1 - 9.5e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UDG PF03167.19 CEG45810.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily RRM_1 PF00076.22 CEG45811.1 - 0.0035 17.1 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CEG45811.1 - 3.5 8.2 10.5 6 7.5 10.5 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bromodomain PF00439.25 CEG45812.1 - 3.3e-21 75.2 0.0 1.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 CEG45812.1 - 1e-10 41.6 1.0 1.6e-10 41.0 1.0 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Sun2_CC2 PF18580.1 CEG45813.1 - 0.093 13.0 0.3 1.7 8.9 0.1 2.4 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 DUF4924 PF16271.5 CEG45815.1 - 0.017 15.1 0.2 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4924) protein_MS5 PF04776.12 CEG45815.1 - 0.074 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein MS5 WD40 PF00400.32 CEG45816.1 - 7.6e-08 32.9 12.4 1.6 9.7 0.0 8.5 9 0 0 9 9 9 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 CEG45816.1 - 0.0032 16.9 0.2 0.0067 15.9 0.2 1.6 1 0 0 1 1 1 1 EF hand ANAPC4_WD40 PF12894.7 CEG45816.1 - 0.0076 16.5 0.0 1.6 9.1 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos_2 PF14529.6 CEG45816.1 - 0.02 14.8 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase EF-hand_7 PF13499.6 CEG45816.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair MBOAT PF03062.19 CEG45818.1 - 3.3e-06 26.7 0.4 3.3e-06 26.7 0.4 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 CEG45818.1 - 0.46 10.8 1.4 0.67 10.3 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1925) Complex1_LYR PF05347.15 CEG45822.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) VEGFR-2_TMD PF17988.1 CEG45825.1 - 0.048 13.1 0.3 0.07 12.6 0.3 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain LRR_3 PF07725.12 CEG45825.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Leucine Rich Repeat EF-hand_1 PF00036.32 CEG45828.1 - 0.00015 21.1 0.4 0.078 12.6 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 CEG45828.1 - 0.0004 20.8 6.6 0.27 11.7 0.1 4.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG45828.1 - 0.00067 19.4 1.1 0.083 12.9 0.0 4.3 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 CEG45828.1 - 0.035 14.0 0.0 0.65 9.9 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair Tcp11 PF05794.13 CEG45829.1 - 5.5e-45 154.3 5.5 5.5e-45 154.3 5.5 2.8 2 1 0 3 3 3 1 T-complex protein 11 FERM_M PF00373.18 CEG45829.1 - 3 8.3 4.5 1.5 9.3 1.3 2.2 2 0 0 2 2 2 0 FERM central domain Rcd1 PF04078.13 CEG45830.1 - 5e-110 366.9 1.6 1.6e-100 335.7 0.2 2.0 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like Amidohydro_1 PF01979.20 CEG45831.1 - 3.8e-57 194.2 0.0 4.4e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEG45831.1 - 2e-10 40.8 0.0 2.1e-06 27.5 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family Helicase_C PF00271.31 CEG45832.1 - 3e-15 56.5 0.0 1.2e-14 54.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain XPG_I PF00867.18 CEG45832.1 - 1.3e-10 41.5 0.0 4.2e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 XPG I-region DEAD PF00270.29 CEG45832.1 - 5.1e-07 29.6 0.2 5.1e-07 29.6 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 CEG45832.1 - 5.4e-07 29.9 0.3 3.1e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_11 PF13086.6 CEG45832.1 - 8.4e-05 22.5 3.2 0.00023 21.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain XPG_I_2 PF12813.7 CEG45832.1 - 0.00016 21.3 1.3 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing AAA_22 PF13401.6 CEG45832.1 - 0.0048 17.2 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEG45832.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 CEG45832.1 - 0.055 14.0 0.7 0.86 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEG45832.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CEG45832.1 - 0.25 11.9 1.3 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 ABC transporter CTV_P33 PF07184.11 CEG45836.1 - 0.033 13.3 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein CxC6 PF18721.1 CEG45837.1 - 5.6 7.3 19.3 1.8 8.9 3.4 3.0 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases 2OG-FeII_Oxy_3 PF13640.6 CEG45839.1 - 5.2e-08 33.7 0.0 1.1e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GlcNAc PF11397.8 CEG45841.1 - 8.9e-58 196.4 2.9 2.3e-53 181.9 0.9 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Abhydrolase_3 PF07859.13 CEG45841.1 - 4.9e-13 49.4 0.0 1.4e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG45841.1 - 2.8e-10 39.9 1.0 4.8e-05 22.7 0.7 2.6 2 1 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 CEG45841.1 - 7.2e-10 38.3 3.4 8.5e-10 38.1 1.1 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CEG45841.1 - 5.6e-07 30.4 0.3 1.3e-06 29.2 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CEG45841.1 - 8.6e-05 22.1 0.3 0.037 13.5 0.0 3.1 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CEG45841.1 - 0.0053 15.7 0.1 0.0097 14.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 CEG45841.1 - 0.029 14.0 0.5 0.13 11.9 0.5 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 CEG45841.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) G-patch PF01585.23 CEG45842.1 - 9.4e-14 51.0 1.1 2.2e-13 49.9 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEG45842.1 - 6.5e-07 29.3 1.0 4.3e-06 26.7 0.7 2.2 2 0 0 2 2 2 1 G-patch domain DNA_pol3_delta2 PF13177.6 CEG45843.1 - 1.1e-09 38.2 0.0 2.1e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CEG45843.1 - 3.2e-07 30.8 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEG45843.1 - 5.2e-06 26.5 0.0 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain Rep_fac_C PF08542.11 CEG45843.1 - 0.00012 22.4 0.2 0.00041 20.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CEG45843.1 - 0.0035 17.6 0.1 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG45843.1 - 0.01 16.2 0.1 0.05 14.0 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain MyTH4 PF00784.17 CEG45843.1 - 0.011 16.2 1.9 0.059 13.9 0.1 2.4 2 1 1 3 3 3 0 MyTH4 domain AAA_5 PF07728.14 CEG45843.1 - 0.03 14.3 0.4 0.13 12.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CEG45843.1 - 0.041 14.4 0.0 0.069 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 CEG45843.1 - 0.055 13.2 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Resolvase PF00239.21 CEG45843.1 - 0.056 13.6 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain AAA_23 PF13476.6 CEG45843.1 - 0.08 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEG45843.1 - 0.15 12.2 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 CEG45843.1 - 0.17 11.6 0.1 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain VWA PF00092.28 CEG45844.1 - 1.4e-09 38.4 0.0 3.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CEG45844.1 - 5.9e-09 36.5 0.0 2.8e-08 34.4 0.0 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 CEG45844.1 - 0.00017 19.9 0.1 0.00017 19.9 0.1 2.0 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CEG45844.1 - 0.0003 20.1 0.1 0.00061 19.1 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 CEG45844.1 - 0.018 15.1 1.3 0.036 14.1 0.0 2.2 2 0 0 2 2 2 0 Dynamin family VWA_CoxE PF05762.14 CEG45844.1 - 0.042 13.2 0.0 0.43 9.9 0.0 2.2 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein MMR_HSR1 PF01926.23 CEG45844.1 - 0.044 13.9 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Chorein_N PF12624.7 CEG45845.1 - 2e-18 66.6 0.0 1.4e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CEG45845.1 - 1.2e-17 64.3 0.0 3.9e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CEG45845.1 - 5.8e-05 23.4 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 CEG45845.1 - 0.00055 19.8 0.1 0.0078 16.0 0.0 3.0 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Retrotran_gag_2 PF14223.6 CEG45846.1 - 0.0097 15.6 0.1 0.015 15.0 0.1 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type LOR PF04525.12 CEG45849.1 - 1.5e-05 24.6 0.0 3.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 LURP-one-related SieB PF14163.6 CEG45850.1 - 0.12 11.9 0.1 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Super-infection exclusion protein B UBA_3 PF09288.10 CEG45851.1 - 0.043 13.6 0.8 0.14 12.0 0.8 1.9 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Rab5-bind PF09311.11 CEG45851.1 - 0.67 9.3 9.9 0.59 9.5 0.8 2.4 2 0 0 2 2 2 0 Rabaptin-like protein Fil_haemagg PF05594.14 CEG45853.1 - 0.077 13.6 9.7 0.089 13.3 9.7 1.1 1 0 0 1 1 1 0 Haemagluttinin repeat Methyltransf_25 PF13649.6 CEG45854.1 - 4.6e-06 27.2 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG45854.1 - 0.00096 19.8 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG45854.1 - 0.12 13.1 0.0 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Stap_Strp_toxin PF01123.20 CEG45854.1 - 0.15 12.9 0.0 14 6.6 0.0 2.3 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain Methyltransf_31 PF13847.6 CEG45854.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain IBR PF01485.21 CEG45855.1 - 6.9e-08 32.6 5.6 6.9e-08 32.6 5.6 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CEG45855.1 - 1.2e-05 25.2 4.6 1.2e-05 25.2 4.6 3.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEG45855.1 - 2.8e-05 24.4 2.7 2.8e-05 24.4 2.7 4.8 4 2 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 CEG45855.1 - 0.00018 21.4 5.2 0.00018 21.4 5.2 5.1 4 1 1 5 5 5 1 zinc-RING finger domain zf-UDP PF14569.6 CEG45855.1 - 0.013 15.5 1.9 0.013 15.5 1.9 3.1 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CEG45855.1 - 0.014 15.6 6.2 0.014 15.6 6.2 4.8 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING Yip1 PF04893.17 CEG45855.1 - 0.59 9.8 9.1 1 9.1 9.1 1.3 1 0 0 1 1 1 0 Yip1 domain zf-NADH-PPase PF09297.11 CEG45855.1 - 0.95 9.2 9.9 0.87 9.3 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF4199 PF13858.6 CEG45855.1 - 3.6 8.0 6.3 0.95 9.8 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) PRA1 PF03208.19 CEG45855.1 - 4.5 6.9 14.0 9.1 5.9 14.0 1.4 1 0 0 1 1 1 0 PRA1 family protein PH PF00169.29 CEG45857.1 - 1.8e-05 25.2 0.3 0.0038 17.7 0.3 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 CEG45857.1 - 0.0087 16.4 0.1 0.033 14.6 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CEG45857.1 - 0.54 10.7 3.3 2.2 8.7 0.2 2.2 2 1 1 3 3 3 0 Pleckstrin homology domain Hydrolase_4 PF12146.8 CEG45860.1 - 0.0053 16.1 0.0 0.25 10.6 0.0 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DELLA PF12041.8 CEG45860.1 - 0.1 12.5 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Nipped-B_C PF12830.7 CEG45861.1 - 0.12 12.3 1.0 1.4 8.8 0.1 2.7 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus MatE PF01554.18 CEG45862.1 - 7.9e-20 71.1 13.3 7.9e-20 71.1 13.3 1.6 2 0 0 2 2 2 1 MatE ABC2_membrane PF01061.24 CEG45864.1 - 1.1e-69 234.0 70.6 2.6e-39 134.8 23.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG45864.1 - 5.2e-38 130.7 0.0 2.6e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 CEG45864.1 - 1.1e-08 35.6 0.0 0.00056 20.3 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 CEG45864.1 - 2.8e-08 33.9 2.1 0.012 15.4 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 CEG45864.1 - 1.4e-06 28.1 8.0 4.1e-06 26.6 0.1 3.3 2 1 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 CEG45864.1 - 2e-06 27.8 3.7 0.0081 16.1 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEG45864.1 - 2.4e-05 24.0 6.8 0.019 14.7 0.9 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG45864.1 - 2.7e-05 24.5 1.3 0.08 13.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 CEG45864.1 - 8.6e-05 21.9 1.1 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 CEG45864.1 - 0.00013 21.6 0.3 0.31 10.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CEG45864.1 - 0.0023 17.4 5.2 1.8 8.0 0.1 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG45864.1 - 0.0025 18.3 2.3 0.27 11.7 0.5 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG45864.1 - 0.0027 17.5 0.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG45864.1 - 0.0034 17.9 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CEG45864.1 - 0.0034 16.5 56.9 0.024 13.7 27.9 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein cobW PF02492.19 CEG45864.1 - 0.0054 16.3 1.6 0.62 9.6 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CEG45864.1 - 0.0056 16.8 1.8 0.64 10.1 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 CEG45864.1 - 0.0067 16.9 0.1 8.5 6.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG45864.1 - 0.0072 16.3 0.1 0.4 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 CEG45864.1 - 0.013 15.7 1.1 0.93 9.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CEG45864.1 - 0.017 13.9 0.6 0.64 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 CEG45864.1 - 0.019 14.9 2.8 5.4 6.9 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.13 CEG45864.1 - 0.021 14.0 0.6 0.046 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 CEG45864.1 - 0.023 14.8 3.1 0.36 10.9 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 CEG45864.1 - 0.025 15.0 0.5 1 9.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 CEG45864.1 - 0.069 13.5 0.1 15 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEG45864.1 - 0.11 12.2 1.3 14 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG45864.1 - 0.18 11.9 0.5 11 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CEG45864.1 - 0.24 11.3 0.5 0.67 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PDR_assoc PF08370.11 CEG45864.1 - 0.25 11.1 16.5 0.033 13.9 1.3 4.0 3 0 0 3 3 2 0 Plant PDR ABC transporter associated PduV-EutP PF10662.9 CEG45864.1 - 0.28 10.9 1.5 8.1 6.2 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CEG45864.1 - 1.4 9.2 3.8 25 5.0 1.1 2.5 2 0 0 2 2 2 0 AAA domain RXLR_WY PF18634.1 CEG45866.1 - 0.0027 17.6 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 RXLR phytopathogen effector protein WY-domain Ectoine_synth PF06339.12 CEG45867.1 - 0.09 13.0 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 Ectoine synthase Waikav_capsid_1 PF12264.8 CEG45868.1 - 0.028 13.9 0.1 0.075 12.5 0.1 1.6 1 1 1 2 2 2 0 Waikavirus capsid protein 1 Glyco_hydro_72 PF03198.14 CEG45870.1 - 9.2e-07 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Abp2 PF09441.10 CEG45870.1 - 0.082 13.0 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 ARS binding protein 2 RNF220 PF15926.5 CEG45872.1 - 0.01 15.5 0.1 0.031 13.9 0.1 1.8 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 FAS_N PF17828.1 CEG45872.1 - 0.074 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Transcrip_reg PF01709.20 CEG45873.1 - 1.1e-72 244.3 1.9 1.4e-72 244.0 1.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator NitrOD5 PF11537.8 CEG45873.1 - 0.031 14.4 0.1 8.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Nitrosopumilus output domain 5 Glyoxalase_4 PF13669.6 CEG45873.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3638 PF12340.8 CEG45875.1 - 5.6e-57 192.7 0.0 9.1e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 CEG45875.1 - 1.3e-16 59.7 0.3 2.2e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) IFT20 PF14931.6 CEG45876.1 - 0.15 12.3 4.0 0.28 11.4 0.4 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 E1-E2_ATPase PF00122.20 CEG45877.1 - 6.1e-32 110.6 0.0 6.1e-32 110.6 0.0 3.3 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 CEG45877.1 - 1.1e-08 35.7 0.0 1.5e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG45877.1 - 0.00013 22.0 0.0 0.00094 19.2 0.1 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEG45877.1 - 0.0069 16.0 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus TB2_DP1_HVA22 PF03134.19 CEG45878.1 - 1.5e-26 92.2 1.2 2.8e-26 91.3 1.2 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pribosyltran_N PF13793.6 CEG45879.1 - 1.1e-43 147.8 0.1 1.1e-42 144.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEG45879.1 - 1e-20 74.5 0.1 2.6e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEG45879.1 - 5.8e-07 29.2 0.6 3.9e-06 26.5 0.2 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain HSP90 PF00183.18 CEG45880.1 - 1.5e-105 354.1 2.6 1.1e-102 344.7 0.5 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CEG45880.1 - 3e-10 40.0 1.0 5.6e-10 39.2 0.3 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEG45880.1 - 1.6e-06 28.6 0.3 4.2e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sialidase PF02973.16 CEG45880.1 - 0.069 12.6 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Sialidase, N-terminal domain MCM_N PF14551.6 CEG45880.1 - 0.2 12.3 0.6 5.3 7.7 0.0 2.9 2 0 0 2 2 2 0 MCM N-terminal domain Peptidase_C48 PF02902.19 CEG45882.1 - 1.8e-23 83.6 0.1 5e-23 82.1 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Biotin_carb_C PF02785.19 CEG45882.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain zf-AN1 PF01428.16 CEG45883.1 - 2.8e-09 37.0 8.3 4.7e-09 36.3 8.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Hamartin PF04388.12 CEG45883.1 - 1.4 7.5 4.1 1.5 7.4 4.1 1.0 1 0 0 1 1 1 0 Hamartin protein UPF0547 PF10571.9 CEG45883.1 - 1.5 8.9 5.6 1.2 9.3 3.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FeoB_C PF07664.12 CEG45884.1 - 0.13 11.9 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus THF_DHG_CYH PF00763.23 CEG45885.1 - 1.6e-22 80.0 0.0 4.6e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CEG45885.1 - 2.8e-13 49.5 0.1 5.1e-12 45.4 0.1 2.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 CEG45885.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain GFO_IDH_MocA PF01408.22 CEG45886.1 - 2.1e-21 77.0 0.1 4.5e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEG45886.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CEG45886.1 - 0.0023 18.6 0.0 0.0039 17.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Myc_target_1 PF15179.6 CEG45889.1 - 0.077 12.9 0.3 0.077 12.9 0.3 1.4 2 0 0 2 2 2 0 Myc target protein 1 RXLR PF16810.5 CEG45892.1 - 0.02 15.3 0.1 0.037 14.5 0.1 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity RT_RNaseH PF17917.1 CEG45894.1 - 3.9e-19 68.9 0.2 4.3e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEG45894.1 - 4.3e-07 29.9 0.0 1.4e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CEG45894.1 - 0.011 15.6 0.0 0.012 15.4 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase-like RXLR PF16810.5 CEG45896.1 - 0.015 15.7 1.0 0.02 15.3 1.0 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Fumarate_red_D PF02313.17 CEG45897.1 - 2.6 8.2 10.2 1.2 9.2 0.3 2.9 2 1 1 3 3 3 0 Fumarate reductase subunit D Aminotran_3 PF00202.21 CEG45900.1 - 6.7e-54 183.1 0.1 4e-48 164.1 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 CEG45900.1 - 0.0053 16.0 0.0 0.0059 15.8 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Hist_deacetyl PF00850.19 CEG45902.1 - 1.4e-79 267.8 0.2 1.9e-79 267.3 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain bPH_6 PF10756.9 CEG45902.1 - 0.0024 17.9 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain His_Phos_1 PF00300.22 CEG45907.1 - 3.7e-33 114.9 0.0 5.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glycos_transf_4 PF00953.21 CEG45907.1 - 2e-32 112.4 9.0 2e-32 112.4 9.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 4 RRM_4 PF10598.9 CEG45908.1 - 0.0029 17.9 0.1 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 FGGY_C PF02782.16 CEG45908.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Med26 PF08711.11 CEG45908.1 - 0.011 15.7 0.5 0.039 14.0 0.5 2.0 1 0 0 1 1 1 0 TFIIS helical bundle-like domain ADIP PF11559.8 CEG45910.1 - 0.033 14.3 0.5 0.033 14.3 0.5 4.1 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding TUDOR_5 PF18359.1 CEG45910.1 - 0.039 13.6 2.1 0.091 12.5 2.1 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 APC_u14 PF16635.5 CEG45910.1 - 0.067 13.7 0.8 0.067 13.7 0.8 1.9 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Agenet PF05641.12 CEG45910.1 - 0.22 12.0 4.4 2.3 8.8 1.7 2.6 2 0 0 2 2 2 0 Agenet domain Spin-Ssty PF02513.17 CEG45910.1 - 0.92 9.3 3.3 1.9 8.3 3.3 1.5 1 0 0 1 1 1 0 Spin/Ssty Family Fimbrial_PilY2 PF14481.6 CEG45913.1 - 0.12 12.0 0.2 0.23 11.2 0.1 1.5 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 LPD26 PF18842.1 CEG45913.1 - 0.18 11.8 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 PSA_CBD PF18341.1 CEG45915.1 - 0.051 13.6 0.0 7 6.8 0.0 2.0 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Importin_rep_4 PF18808.1 CEG45916.1 - 3.1e-09 37.0 9.4 6.8e-09 35.9 0.0 4.7 5 0 0 5 5 5 1 Importin repeat HEAT_2 PF13646.6 CEG45916.1 - 5.6e-05 23.4 0.2 0.0039 17.5 0.1 7.4 6 3 4 10 10 10 2 HEAT repeats DUF4704 PF15787.5 CEG45916.1 - 0.001 18.4 3.2 0.0018 17.6 0.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) HEAT PF02985.22 CEG45916.1 - 0.0045 17.1 17.7 5.4 7.5 0.0 8.8 8 0 0 8 8 8 1 HEAT repeat DUF3385 PF11865.8 CEG45916.1 - 0.014 15.3 0.7 22 4.9 0.0 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) CLASP_N PF12348.8 CEG45916.1 - 0.16 11.5 7.2 1.4 8.5 0.1 4.6 5 0 0 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 CEG45916.1 - 0.3 11.6 27.1 7.8 7.1 0.1 9.6 10 1 1 11 11 11 0 HEAT-like repeat RGS PF00615.19 CEG45917.1 - 1.1e-74 248.3 0.7 2e-19 70.0 0.1 4.4 4 0 0 4 4 4 4 Regulator of G protein signaling domain VWA_2 PF13519.6 CEG45918.1 - 0.15 12.7 10.0 2.8 8.6 0.1 4.4 3 2 2 5 5 5 0 von Willebrand factor type A domain KASH_CCD PF14662.6 CEG45918.1 - 0.64 9.8 80.6 3.9 7.2 9.5 5.2 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH MtrB PF05440.12 CEG45918.1 - 1 9.8 5.8 39 4.8 0.0 4.4 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B GTP_EFTU_D3 PF03143.17 CEG45919.1 - 1.5e-42 144.4 0.0 3.2e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 CEG45919.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEG45919.1 - 2.5e-14 53.4 0.2 5.8e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FlpD PF02662.16 CEG45919.1 - 0.0037 17.3 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 CEG45919.1 - 0.0091 15.9 0.4 0.022 14.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF3430 PF11912.8 CEG45920.1 - 0.00082 19.5 5.4 0.37 10.8 5.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Arm PF00514.23 CEG45921.1 - 1.8e-05 24.6 26.1 0.27 11.4 0.3 9.1 11 0 0 11 11 11 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CEG45921.1 - 0.011 15.8 16.8 0.24 11.4 0.0 6.8 7 1 0 7 7 7 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 CEG45921.1 - 0.022 15.4 0.7 55 4.9 0.0 5.2 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat WW PF00397.26 CEG45921.1 - 0.076 13.1 4.1 0.03 14.4 0.5 2.2 2 0 0 2 2 2 0 WW domain Tyosinase_C PF18132.1 CEG45921.1 - 0.66 10.7 3.1 0.65 10.7 0.0 2.7 3 0 0 3 3 3 0 Tyosinase C-terminal domain DAO PF01266.24 CEG45922.1 - 3.2e-52 178.3 0.0 4.4e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CEG45922.1 - 9.4e-37 125.7 0.1 1.7e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CEG45922.1 - 1.2e-10 41.1 3.7 7.4e-06 25.3 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CEG45922.1 - 3e-05 23.4 0.0 9e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEG45922.1 - 6.7e-05 22.3 0.3 0.00061 19.1 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CEG45922.1 - 0.00043 19.5 3.2 0.018 14.1 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CEG45922.1 - 0.0011 18.4 3.7 0.0011 18.4 3.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEG45922.1 - 0.0041 17.3 0.6 0.019 15.1 0.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEG45922.1 - 0.0068 15.2 0.8 0.012 14.3 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Sacchrp_dh_NADP PF03435.18 CEG45922.1 - 0.021 15.1 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 CEG45922.1 - 0.039 13.2 0.8 0.19 10.9 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEG45922.1 - 0.16 11.2 1.3 0.3 10.3 0.1 2.0 3 0 0 3 3 3 0 Thi4 family zf-U11-48K PF05253.12 CEG45923.1 - 0.057 13.4 0.2 0.08 12.9 0.2 1.3 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Pou PF00157.17 CEG45926.1 - 0.046 13.7 0.3 0.057 13.4 0.3 1.3 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain APH PF01636.23 CEG45927.1 - 8.3e-06 25.9 0.1 8.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CEG45927.1 - 0.00051 19.5 0.0 0.00065 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 CEG45927.1 - 0.00052 19.7 0.0 0.00085 19.0 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CEG45927.1 - 0.0035 16.7 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG45927.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 CEG45927.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RXLR_WY PF18634.1 CEG45928.1 - 3.3e-23 81.4 4.2 0.0003 20.6 0.0 6.2 6 0 0 6 6 6 5 RXLR phytopathogen effector protein WY-domain PI3_PI4_kinase PF00454.27 CEG45929.1 - 1.2e-44 153.0 0.0 4.5e-44 151.1 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 CEG45929.1 - 1.6e-18 66.5 12.8 1.1e-17 63.7 7.1 3.8 2 1 0 2 2 2 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 CEG45929.1 - 3.8e-13 49.0 1.4 3.8e-13 49.0 1.4 2.1 2 0 0 2 2 2 1 FATC domain T7SS_ESX_EspC PF10824.8 CEG45929.1 - 0.0037 17.7 1.5 0.36 11.3 0.1 3.1 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm ApoLp-III PF07464.11 CEG45929.1 - 0.057 13.5 6.6 0.66 10.1 0.1 3.6 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) FRB_dom PF08771.11 CEG45929.1 - 0.072 13.5 5.9 2.1 8.8 0.4 5.2 4 1 1 5 5 5 0 FKBP12-rapamycin binding domain Sec23_trunk PF04811.15 CEG45930.1 - 8.6e-46 156.5 0.0 1.3e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEG45930.1 - 3.7e-19 68.5 0.3 1.1e-18 67.0 0.3 1.8 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEG45930.1 - 4.2e-19 69.1 0.0 8.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEG45930.1 - 2.5e-13 49.8 3.8 6e-13 48.6 3.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger MFS_2 PF13347.6 CEG45932.1 - 3.4e-15 55.5 7.1 3.4e-15 55.5 7.1 2.6 2 1 1 3 3 3 1 MFS/sugar transport protein GAS PF13851.6 CEG45934.1 - 0.0011 18.4 16.0 0.0011 18.4 16.0 7.3 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding DYW_deaminase PF14432.6 CEG45934.1 - 0.012 15.5 3.9 0.045 13.6 3.5 2.3 1 1 0 1 1 1 0 DYW family of nucleic acid deaminases ThiS PF02597.20 CEG45934.1 - 0.058 14.0 0.7 0.058 14.0 0.7 3.9 2 1 0 3 3 3 0 ThiS family HOOK PF05622.12 CEG45934.1 - 8.5 4.4 104.7 0.33 9.0 17.0 2.5 2 1 0 2 2 2 0 HOOK protein Sec7 PF01369.20 CEG45935.1 - 4.4e-55 186.2 0.9 7.5e-55 185.5 0.9 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEG45935.1 - 1.7e-16 60.5 0.9 1.7e-16 60.5 0.9 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HNF_C PF09354.10 CEG45935.1 - 0.02 15.9 0.0 0.073 14.1 0.0 2.0 1 0 0 1 1 1 0 HNF3 C-terminal domain Diphthami_syn_2 PF01902.17 CEG45936.1 - 6.7e-39 133.6 0.1 1.1e-38 133.0 0.1 1.3 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CEG45936.1 - 2.4e-29 101.8 0.1 8.2e-12 45.2 0.0 4.2 4 0 0 4 4 4 4 Endoribonuclease L-PSP Fip1 PF05182.13 CEG45937.1 - 2.8e-23 81.2 0.3 2.8e-23 81.2 0.3 1.8 2 0 0 2 2 2 1 Fip1 motif Ribosomal_L21e PF01157.18 CEG45938.1 - 4.2e-33 113.2 3.9 1.1e-32 111.9 3.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L21e PIH1 PF08190.12 CEG45938.1 - 3.1e-27 95.1 0.0 7.2e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CEG45938.1 - 5.4e-06 26.7 0.1 3e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 PIH1 CS-like domain Ala_racemase_N PF01168.20 CEG45939.1 - 9.3e-23 81.0 0.0 1.1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PRANC PF09372.10 CEG45942.1 - 0.17 12.3 0.6 1.4 9.3 0.1 2.4 3 0 0 3 3 3 0 PRANC domain RHSP PF07999.11 CEG45945.1 - 0.016 14.1 0.3 0.29 9.9 0.1 2.6 3 1 0 3 3 3 0 Retrotransposon hot spot protein FtsK_SpoIIIE PF01580.18 CEG45945.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Chloroplast_duf PF14476.6 CEG45946.1 - 0.23 10.4 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Petal formation-expressed Cullin PF00888.22 CEG45947.1 - 4.6e-194 646.5 15.4 5.7e-194 646.2 15.4 1.1 1 0 0 1 1 1 1 Cullin family Trypsin PF00089.26 CEG45947.1 - 1.7e-42 145.7 0.0 2.8e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Cullin_Nedd8 PF10557.9 CEG45947.1 - 8.3e-23 80.2 3.4 8.8e-23 80.1 1.4 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF316 PF03761.15 CEG45947.1 - 0.024 14.2 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 SecA_SW PF07516.13 CEG45947.1 - 0.073 13.1 0.2 0.073 13.1 0.2 3.1 3 1 1 4 4 4 0 SecA Wing and Scaffold domain TBP PF00352.21 CEG45948.1 - 4.6e-42 141.9 0.0 1.2e-27 95.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CEG45948.1 - 0.0023 18.0 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Renin_r PF07850.14 CEG45949.1 - 2.3e-05 24.9 1.6 8e-05 23.2 1.6 2.0 1 1 0 1 1 1 1 Renin receptor-like protein IATP PF04568.12 CEG45950.1 - 0.0017 18.7 1.0 0.0029 18.0 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP ApoL PF05461.11 CEG45950.1 - 0.017 14.5 1.2 0.021 14.1 1.2 1.2 1 0 0 1 1 1 0 Apolipoprotein L Thioredoxin_8 PF13905.6 CEG45950.1 - 0.094 13.1 0.0 0.099 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like TAFII55_N PF04658.13 CEG45951.1 - 4.6e-23 81.7 1.3 1e-22 80.6 0.1 2.1 2 1 0 2 2 2 1 TAFII55 protein conserved region Mic1 PF07035.12 CEG45952.1 - 1.5e-14 54.0 0.0 2.7e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Colon cancer-associated protein Mic1-like Nucleoside_tran PF01733.18 CEG45954.1 - 1.6e-21 77.0 6.2 1.6e-21 77.0 6.2 2.4 2 1 0 2 2 2 1 Nucleoside transporter LapA_dom PF06305.11 CEG45954.1 - 3.4 7.6 5.7 10 6.0 0.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SNARE PF05739.19 CEG45955.1 - 1.7e-11 43.9 3.4 3.8e-11 42.8 3.4 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CEG45955.1 - 4.6e-05 23.2 5.8 0.0011 18.6 0.1 2.4 2 0 0 2 2 2 2 Syntaxin Apolipoprotein PF01442.18 CEG45955.1 - 0.00042 20.2 1.7 0.00042 20.2 1.7 1.9 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain Dak1_2 PF13684.6 CEG45955.1 - 0.022 13.9 1.3 0.04 13.0 1.3 1.4 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF4240 PF14024.6 CEG45955.1 - 0.046 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) DUF1664 PF07889.12 CEG45955.1 - 9.9 6.2 8.1 0.84 9.7 1.3 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) zf-CCCH PF00642.24 CEG45956.1 - 6.1e-05 22.8 25.6 0.0002 21.2 3.7 4.1 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CEG45956.1 - 0.00016 21.9 2.7 0.00016 21.9 2.7 2.5 1 1 1 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 CEG45956.1 - 0.0019 18.2 32.5 0.032 14.3 8.0 4.9 4 1 0 4 4 4 3 Zinc finger domain Torus PF16131.5 CEG45956.1 - 0.012 16.3 24.6 0.062 14.0 0.3 3.9 2 1 1 4 4 4 0 Torus domain zf-CCCH_4 PF18044.1 CEG45956.1 - 3.6 7.5 23.4 0.55 10.1 2.7 4.5 4 0 0 4 4 4 0 CCCH-type zinc finger MFA1_2 PF17317.2 CEG45962.1 - 3.2 7.6 5.3 5.7 6.8 1.5 2.6 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Hamartin PF04388.12 CEG45963.1 - 2.1 6.9 12.0 2.4 6.7 12.0 1.1 1 0 0 1 1 1 0 Hamartin protein Mucin PF01456.17 CEG45964.1 - 0.036 14.0 11.4 0.053 13.5 11.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein BDV_P10 PF06515.11 CEG45968.1 - 0.17 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P10 protein LRR_9 PF14580.6 CEG45969.1 - 4.4e-55 185.9 48.8 5.6e-16 58.5 5.3 8.4 4 3 2 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 CEG45969.1 - 2.3e-52 174.1 118.4 3.9e-07 30.3 1.3 15.9 12 2 7 19 19 19 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG45969.1 - 2.6e-34 116.8 102.6 7.4e-08 32.0 9.7 11.9 10 2 2 12 12 12 11 Leucine rich repeat DUF4472 PF14739.6 CEG45969.1 - 0.46 11.3 3.4 0.9 10.3 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Metallophos PF00149.28 CEG45970.1 - 2e-15 57.9 4.5 3e-15 57.3 4.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEG45970.1 - 1.2e-09 38.6 4.9 2e-08 34.6 4.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CEG45970.1 - 0.012 15.0 0.0 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF3687 PF12459.8 CEG45970.1 - 2.4 7.7 7.8 5.4 6.6 7.8 1.6 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein FH2 PF02181.23 CEG45971.1 - 8.1e-74 249.0 0.5 1.5e-73 248.1 0.5 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG45971.1 - 9.7e-47 159.2 11.0 2.9e-11 44.0 0.1 5.1 5 0 0 5 5 5 4 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 CEG45971.1 - 1.5e-06 27.9 1.0 4.1e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain PhoD PF09423.10 CEG45973.1 - 4.1e-23 82.0 0.0 1.1e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase Meckelin PF09773.9 CEG45975.1 - 5.7e-155 517.6 13.4 8.5e-155 517.0 13.4 1.3 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) PRKCSH PF07915.13 CEG45976.1 - 2.1e-10 41.5 3.6 7.4e-10 39.7 3.6 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CEG45976.1 - 2.9e-09 36.8 1.2 5.8e-09 35.8 1.2 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 CEG45976.1 - 2.3e-05 24.5 0.3 9.6e-05 22.5 0.3 2.0 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CEG45976.1 - 0.018 15.2 0.3 0.065 13.5 0.1 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I DNA_RNApol_7kD PF03604.13 CEG45976.1 - 0.05 13.3 2.8 0.42 10.3 0.0 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 CEG45976.1 - 0.29 11.1 4.5 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain EamA PF00892.20 CEG45979.1 - 1.1e-09 38.5 29.6 3.9e-08 33.5 12.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CEG45979.1 - 0.011 15.1 15.5 0.016 14.6 15.5 1.3 1 0 0 1 1 1 0 Triose-phosphate Transporter family OAD_gamma PF04277.13 CEG45979.1 - 0.17 12.5 1.6 26 5.5 0.0 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4653 PF15546.6 CEG45981.1 - 0.44 10.1 2.2 0.81 9.3 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) RNase_T PF00929.24 CEG45982.1 - 9.3e-06 26.3 0.1 2.5e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 CEG45982.1 - 0.064 13.5 1.7 0.087 13.1 0.1 2.0 2 0 0 2 2 2 0 ElonginA binding-protein 1 TPR_12 PF13424.6 CEG45988.1 - 1.9e-07 31.3 4.9 0.00085 19.6 0.6 4.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG45988.1 - 5.1e-05 23.0 4.7 0.23 11.4 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat RNaseH_like PF04308.12 CEG45988.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Ribonuclease H-like TPR_2 PF07719.17 CEG45988.1 - 0.46 10.7 2.1 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 CEG45989.1 - 1.3e-18 67.6 1.3 7.3e-18 65.2 1.3 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase HMG_box_5 PF14887.6 CEG45989.1 - 0.0045 16.9 0.5 0.014 15.4 0.3 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box 5 HMG_box_2 PF09011.10 CEG45989.1 - 0.0057 17.2 0.3 0.014 15.9 0.2 1.7 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 CEG45989.1 - 0.0075 16.7 0.4 0.019 15.3 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF5392 PF17370.2 CEG45989.1 - 0.0089 16.1 0.7 0.053 13.6 0.4 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5392) Mannosyl_trans3 PF11051.8 CEG45990.1 - 7.2e-29 101.0 0.0 5.5e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Mannosyltransferase putative Myb_DNA-binding PF00249.31 CEG45991.1 - 7.8e-43 144.4 8.1 4.3e-14 52.4 1.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG45991.1 - 6.6e-33 112.8 0.2 5.2e-13 49.0 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CEG45991.1 - 0.063 13.3 0.0 6.4 6.8 0.0 2.6 2 1 0 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 CEG45991.1 - 0.31 11.4 1.4 39 4.7 0.1 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain EF-hand_1 PF00036.32 CEG45992.1 - 7.8e-35 115.8 19.5 2.7e-09 35.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG45992.1 - 1.6e-30 105.3 11.8 2.7e-16 59.8 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG45992.1 - 5.4e-27 91.4 11.8 1.3e-09 37.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG45992.1 - 4.4e-26 90.5 12.2 3.7e-12 45.9 1.3 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEG45992.1 - 9.5e-18 62.8 18.4 4.8e-06 25.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEG45992.1 - 1.7e-15 57.1 0.6 8.5e-08 32.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEG45992.1 - 3.6e-06 26.9 8.7 0.22 11.5 1.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG45992.1 - 0.00011 22.5 2.7 0.037 14.4 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CEG45992.1 - 0.00046 20.5 1.7 0.28 11.5 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CEG45992.1 - 0.00047 20.3 0.2 0.6 10.3 0.2 2.5 2 0 0 2 2 2 2 Dockerin type I domain SurA_N_3 PF13624.6 CEG45992.1 - 0.00058 19.7 2.9 0.17 11.6 0.4 2.2 1 1 0 2 2 2 2 SurA N-terminal domain SurA_N_2 PF13623.6 CEG45992.1 - 0.014 15.3 4.5 1.3 8.9 0.4 2.8 1 1 1 2 2 2 0 SurA N-terminal domain PMBR PF09373.10 CEG45992.1 - 0.016 15.4 1.1 43 4.5 0.0 4.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF853 PF05872.12 CEG45992.1 - 0.025 13.2 0.2 0.49 8.9 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SUB1_ProdP9 PF18213.1 CEG45992.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.0 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 Caleosin PF05042.13 CEG45992.1 - 0.027 14.4 1.7 7.7 6.4 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein EF-hand_11 PF08976.11 CEG45992.1 - 0.071 14.0 0.4 12 6.8 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LETM1 PF07766.13 CEG45992.1 - 0.082 12.2 2.9 0.14 11.5 1.4 2.0 1 1 0 1 1 1 0 LETM1-like protein DUF3008 PF11450.8 CEG45992.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.7 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) DUF4601 PF15373.6 CEG45992.1 - 0.22 10.5 0.1 0.43 9.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) DUF21 PF01595.20 CEG45992.1 - 0.25 11.0 0.4 0.74 9.5 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Phg_2220_C PF09524.10 CEG45992.1 - 0.73 9.9 4.4 4.9 7.3 0.1 2.9 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Gp-FAR-1 PF05823.12 CEG45992.1 - 1.6 9.0 7.7 1 9.7 0.2 2.9 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1542 PF07564.11 CEG45992.1 - 3.5 7.8 7.8 3.9 7.7 1.1 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Styelin PF17562.2 CEG45992.1 - 8.4 6.8 8.2 0.62 10.5 1.6 2.5 2 2 0 2 2 2 0 Styelin Noc2 PF03715.13 CEG45993.1 - 1.8e-82 276.9 0.5 1.8e-82 276.9 0.5 1.7 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 CEG45993.1 - 0.22 9.7 36.2 0.23 9.7 0.3 3.0 3 0 0 3 3 3 0 Nop14-like family Trypan_PARP PF05887.11 CEG45993.1 - 1.3 9.0 6.9 2.6 8.0 6.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 CEG45994.1 - 1.5e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG45994.1 - 3.2e-28 98.7 0.0 4.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG45994.1 - 2.9e-06 26.8 0.4 5.3e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG45994.1 - 5.4e-05 22.7 0.3 0.00016 21.1 0.1 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG45994.1 - 0.00015 20.7 0.1 0.002 17.0 0.1 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG45994.1 - 0.00017 21.6 1.0 0.011 15.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEG45994.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CEG45994.1 - 0.075 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CEG45994.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_16 PF10294.9 CEG45995.1 - 4.2e-13 49.4 0.1 4.6e-11 42.7 0.1 2.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG45995.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG45995.1 - 4.3e-05 23.1 0.0 8.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CEG45995.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CEG45995.1 - 0.00073 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG45995.1 - 0.0014 19.3 0.0 0.0042 17.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HTH_Tnp_Tc3_2 PF01498.18 CEG45995.1 - 0.021 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Transposase TehB PF03848.14 CEG45995.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 CEG45995.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NifU_N PF01592.16 CEG45996.1 - 1.7e-35 122.0 0.1 1.9e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF676 PF05057.14 CEG45997.1 - 1.7e-26 93.1 0.1 2.1e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CEG45997.1 - 2.1e-05 24.4 0.1 0.00046 20.0 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 CEG45997.1 - 0.00038 20.4 0.0 0.00044 20.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 CEG45997.1 - 0.00051 19.9 0.0 0.0006 19.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 CEG45997.1 - 0.0034 16.6 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEG45997.1 - 0.021 15.5 0.0 0.048 14.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CEG45997.1 - 0.036 13.6 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CEG45997.1 - 0.098 11.9 0.0 2.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 CEG45997.1 - 0.18 11.7 0.1 0.22 11.4 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) FlbD PF06289.11 CEG45998.1 - 0.1 12.2 0.3 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins zf-RING_2 PF13639.6 CEG46000.1 - 8.6e-15 54.8 6.4 1.3e-14 54.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG46000.1 - 6.2e-11 42.0 6.7 9.9e-11 41.3 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG46000.1 - 6.2e-11 41.8 3.5 1.2e-10 40.9 3.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CEG46000.1 - 1.8e-08 34.5 6.0 3.4e-08 33.7 6.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG46000.1 - 2.4e-07 30.6 4.4 3.7e-07 30.0 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG46000.1 - 5.9e-07 29.2 4.1 8.9e-07 28.7 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG46000.1 - 1.1e-06 28.6 3.1 2.7e-06 27.3 3.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG46000.1 - 1.3e-06 28.1 6.2 2.1e-06 27.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG46000.1 - 0.00013 21.7 4.3 0.00022 21.0 4.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CEG46000.1 - 0.003 17.1 4.7 0.0046 16.5 4.7 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CEG46000.1 - 0.0047 17.0 4.2 0.0094 16.0 4.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 CEG46000.1 - 0.01 15.8 0.5 0.023 14.7 0.1 1.7 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zinc_ribbon_16 PF17034.5 CEG46000.1 - 0.021 15.0 1.5 0.037 14.3 1.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family DUF1272 PF06906.11 CEG46000.1 - 0.06 13.5 2.9 0.11 12.6 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PHD PF00628.29 CEG46000.1 - 0.081 12.8 5.1 0.17 11.8 5.1 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 CEG46000.1 - 0.15 11.9 3.4 0.42 10.5 3.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain NAM-associated PF14303.6 CEG46000.1 - 0.18 12.5 0.9 0.28 11.9 0.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-C3H2C3 PF17122.5 CEG46000.1 - 0.33 11.0 6.1 0.73 9.9 6.1 1.7 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CEG46000.1 - 0.33 10.9 4.0 0.38 10.7 1.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 CEG46000.1 - 0.51 10.5 5.4 3.6 7.8 5.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 CEG46000.1 - 0.9 9.7 5.6 2.1 8.5 5.6 1.6 1 0 0 1 1 1 0 RING-variant domain Nucleoporin_FG PF13634.6 CEG46001.1 - 0.002 18.9 2.2 0.0047 17.7 0.8 2.2 1 1 1 2 2 2 1 Nucleoporin FG repeat region Pneumovirus_M2 PF06436.11 CEG46001.1 - 0.027 13.9 1.9 0.048 13.1 1.9 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) PI-PLC-X PF00388.19 CEG46003.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 CEG46003.1 - 0.21 10.6 0.2 1.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent PAPS_reduct PF01507.19 CEG46004.1 - 2.3e-26 92.9 0.0 1.6e-16 60.9 0.0 2.6 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MMtag PF10159.9 CEG46005.1 - 1.1e-28 99.3 1.4 1.1e-28 99.3 1.4 2.4 2 0 0 2 2 2 1 Multiple myeloma tumor-associated ETRAMP PF09716.10 CEG46005.1 - 0.01 15.9 1.1 0.012 15.7 1.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Endonuc_Holl PF10107.9 CEG46005.1 - 0.48 10.3 6.3 1 9.2 6.3 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase LMBR1 PF04791.16 CEG46005.1 - 2.7 6.8 4.3 3.6 6.4 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S49_N PF08496.10 CEG46005.1 - 7.6 6.6 11.5 16 5.5 11.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal V-SNARE_C PF12352.8 CEG46006.1 - 1.8e-06 28.2 1.4 2.4e-06 27.7 1.4 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Cpn60_TCP1 PF00118.24 CEG46007.1 - 1.2e-170 568.4 2.7 1.4e-170 568.2 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2681 PF10883.8 CEG46009.1 - 0.25 11.8 4.4 0.43 11.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Radical_SAM_C PF16199.5 CEG46011.1 - 5.8e-20 71.1 0.1 1.2e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CEG46011.1 - 1.9e-16 60.9 0.3 4.3e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CEG46011.1 - 3.9e-08 33.5 0.0 9.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG46011.1 - 2.9e-07 30.5 0.2 7.8e-07 29.1 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG46011.1 - 0.0013 19.1 0.0 0.0029 18.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.22 CEG46012.1 - 0.0021 16.9 0.0 0.0047 15.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.6 CEG46013.1 - 1.1e-34 118.2 7.1 5.3e-08 32.7 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CEG46013.1 - 2.6e-31 107.3 12.9 6.8e-09 35.8 0.2 6.5 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG46013.1 - 7.3e-29 99.1 9.2 9.2e-08 32.1 0.2 6.1 3 1 2 5 5 5 5 Kelch motif Kelch_1 PF01344.25 CEG46013.1 - 1.4e-26 91.8 18.3 6.9e-09 35.2 0.1 6.7 5 3 0 5 5 5 5 Kelch motif BTB PF00651.31 CEG46013.1 - 3e-22 78.9 0.1 2.3e-20 72.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 CEG46013.1 - 9.2e-22 76.6 6.9 7.4e-06 25.8 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEG46013.1 - 2.6e-20 71.5 16.6 9.3e-05 22.2 0.1 6.3 5 3 0 5 5 5 4 Kelch motif BACK PF07707.15 CEG46013.1 - 3.4e-05 23.9 0.2 0.00031 20.8 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch LETM1 PF07766.13 CEG46014.1 - 6.7e-99 330.6 4.1 6.7e-99 330.6 4.1 2.3 2 0 0 2 2 2 1 LETM1-like protein EF-hand_1 PF00036.32 CEG46014.1 - 3.2e-09 35.7 1.3 0.00092 18.6 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEG46014.1 - 1.1e-08 34.7 0.1 4.6e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG46014.1 - 1.6e-06 27.6 0.2 0.11 12.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CEG46014.1 - 1.8e-06 28.3 1.1 1.3e-05 25.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG46014.1 - 0.0002 20.7 7.1 0.014 14.9 0.1 3.9 5 0 0 5 5 5 2 EF hand Ntox27 PF15531.6 CEG46014.1 - 0.013 15.4 0.1 0.039 13.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial toxin 27 DUF4242 PF14026.6 CEG46014.1 - 0.14 12.3 1.3 0.52 10.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) Tox-REase-2 PF15646.6 CEG46014.1 - 0.7 10.1 8.3 1.5 9.0 2.0 3.5 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 2 DUF3349 PF11829.8 CEG46014.1 - 6.4 7.6 12.0 6.8 7.5 0.4 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) SPARC_Ca_bdg PF10591.9 CEG46014.1 - 8.5 6.7 10.3 0.14 12.5 0.4 3.2 4 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region PHP PF02811.19 CEG46015.1 - 2.6e-09 37.6 0.1 3.7e-09 37.1 0.1 1.5 1 1 0 1 1 1 1 PHP domain Kelch_1 PF01344.25 CEG46016.1 - 3.3e-40 135.4 28.7 1e-08 34.6 0.2 7.1 8 0 0 8 8 8 6 Kelch motif Kelch_6 PF13964.6 CEG46016.1 - 1.1e-37 127.0 19.3 5.5e-08 32.8 0.1 6.3 3 3 3 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEG46016.1 - 2.1e-36 123.5 15.0 4.2e-07 30.1 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 CEG46016.1 - 1.3e-32 110.6 12.9 6.4e-06 25.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 CEG46016.1 - 6.2e-32 109.1 17.0 1.7e-06 27.8 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CEG46016.1 - 4.2e-31 106.7 12.3 1.1e-05 25.3 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 CEG46016.1 - 1.2e-18 67.4 0.3 1.3e-17 64.0 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain RAG2 PF03089.14 CEG46016.1 - 0.018 14.1 0.8 1.1 8.2 0.0 3.3 3 1 1 4 4 4 0 Recombination activating protein 2 BACK PF07707.15 CEG46016.1 - 0.056 13.5 0.7 0.47 10.6 0.3 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch WD40 PF00400.32 CEG46017.1 - 4.6e-15 55.7 4.3 2.1e-05 25.2 0.5 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46017.1 - 4.5e-08 33.3 0.0 0.0074 16.6 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CwfJ_C_1 PF04677.15 CEG46019.1 - 7.4e-34 116.2 0.0 5.7e-33 113.4 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CEG46019.1 - 1.4e-10 41.9 0.0 3.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 APH PF01636.23 CEG46020.1 - 1.3e-05 25.3 0.1 1.7e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CEG46020.1 - 0.00031 20.2 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 CEG46020.1 - 0.00049 19.8 0.0 0.00056 19.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CEG46020.1 - 0.00078 18.8 0.0 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG46020.1 - 0.0076 15.9 0.0 0.0091 15.6 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 CEG46020.1 - 0.056 12.4 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.17 CEG46020.1 - 0.24 10.7 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Myb_DNA-binding PF00249.31 CEG46021.1 - 1.5e-12 47.5 0.2 2.9e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG46021.1 - 0.00021 21.5 0.2 0.00037 20.7 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG46021.1 - 0.02 14.8 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like PDZ_6 PF17820.1 CEG46022.1 - 1.8e-05 24.5 0.0 4.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 PDZ domain FerA PF08165.11 CEG46023.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain bZIP_1 PF00170.21 CEG46024.1 - 0.00065 19.8 11.8 0.00065 19.8 11.8 3.0 2 1 1 3 3 3 1 bZIP transcription factor Sigma70_r3 PF04539.16 CEG46024.1 - 0.019 15.0 0.5 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 Sigma-70 region 3 bZIP_2 PF07716.15 CEG46024.1 - 0.027 14.5 12.2 0.027 14.5 12.2 3.8 4 0 0 4 4 4 0 Basic region leucine zipper RQC PF09382.10 CEG46024.1 - 0.037 13.8 0.3 3.7 7.4 0.1 2.7 2 0 0 2 2 2 0 RQC domain SapB_1 PF05184.15 CEG46024.1 - 0.39 10.8 4.6 0.37 10.8 0.2 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 TEX13 PF15186.6 CEG46024.1 - 0.71 9.5 15.5 2.1 8.0 9.5 2.8 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family PP2C_C PF07830.13 CEG46024.1 - 2 8.9 5.0 8.6 6.9 0.8 2.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain YrhK PF14145.6 CEG46026.1 - 0.13 12.1 0.0 5.1 7.0 0.0 2.4 3 0 0 3 3 3 0 YrhK-like protein PHD PF00628.29 CEG46027.1 - 4.6e-25 87.3 68.4 2.5e-09 36.9 13.7 5.0 5 0 0 5 5 5 4 PHD-finger WSD PF15613.6 CEG46027.1 - 6.3e-13 49.0 0.0 6.3e-13 49.0 0.0 4.6 5 3 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CEG46027.1 - 3.5e-10 40.1 0.3 9.4e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 DDT domain PHD_2 PF13831.6 CEG46027.1 - 7.4e-08 31.8 54.0 0.00029 20.3 3.2 6.3 6 0 0 6 6 6 4 PHD-finger WHIM1 PF15612.6 CEG46027.1 - 2e-05 24.0 0.0 5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ricin_B_lectin PF00652.22 CEG46028.1 - 7.7e-14 52.0 7.9 5.3e-13 49.3 7.1 2.6 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEG46028.1 - 0.0011 19.6 6.8 0.01 16.5 0.4 3.8 3 1 1 4 4 4 1 Ricin-type beta-trefoil lectin domain-like Levi_coat PF01819.17 CEG46028.1 - 0.042 13.9 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Levivirus coat protein SYS1 PF09801.9 CEG46029.1 - 0.04 14.1 0.0 0.044 13.9 0.0 1.2 1 1 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Sulfate_transp PF00916.20 CEG46031.1 - 7.4e-69 232.3 10.2 4.8e-39 134.2 0.5 2.4 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 CEG46031.1 - 3e-09 36.5 0.0 6.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CEG46031.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 CEG46031.1 - 1 9.8 21.9 0.035 14.5 4.3 3.5 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily ESCRT-II PF05871.12 CEG46033.1 - 0.0091 16.2 0.1 0.0099 16.1 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PLDc PF00614.22 CEG46037.1 - 1.3e-16 60.0 0.4 3.5e-07 30.1 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEG46037.1 - 2.6e-12 46.8 0.2 2.3e-07 30.7 0.1 3.0 2 1 0 2 2 2 2 PLD-like domain T4SS_CagC PF16943.5 CEG46037.1 - 0.15 12.3 0.8 0.38 10.9 0.2 2.0 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system RNA_pol_A_bac PF01000.26 CEG46039.1 - 0.076 13.4 0.1 0.2 12.1 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain ApoLp-III PF07464.11 CEG46039.1 - 0.084 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) GRASP55_65 PF04495.14 CEG46039.1 - 0.16 12.3 0.1 0.25 11.6 0.1 1.4 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Phage_Coat_B PF05356.11 CEG46040.1 - 0.14 12.1 1.3 0.31 11.0 1.4 1.7 1 1 0 1 1 1 0 Phage Coat protein B MtN3_slv PF03083.16 CEG46041.1 - 2.3e-31 107.7 5.7 9.8e-18 64.0 0.2 2.5 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange FKBP_C PF00254.28 CEG46041.1 - 5.8e-16 58.6 0.1 1.4e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PQ-loop PF04193.14 CEG46041.1 - 2.9e-05 23.7 4.5 0.00033 20.4 0.2 3.3 2 1 1 3 3 3 1 PQ loop repeat LAB_N PF07578.11 CEG46041.1 - 0.25 11.5 0.0 0.25 11.5 0.0 2.4 3 0 0 3 3 3 0 Lipid A Biosynthesis N-terminal domain Rhomboid PF01694.22 CEG46041.1 - 0.65 10.0 7.1 0.15 12.1 3.3 1.8 1 1 0 1 1 1 0 Rhomboid family p31comet PF06581.12 CEG46042.1 - 0.00012 21.4 1.1 0.00084 18.6 0.2 2.0 2 0 0 2 2 2 1 Mad1 and Cdc20-bound-Mad2 binding CobA_CobO_BtuR PF02572.15 CEG46042.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Med6 PF04934.14 CEG46043.1 - 1.8e-38 131.3 0.0 2.2e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component MFS_1 PF07690.16 CEG46046.1 - 1.8e-15 56.7 26.9 2.7e-15 56.1 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ZZ PF00569.17 CEG46046.1 - 2e-09 37.1 4.6 4e-09 36.1 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 CEG46046.1 - 0.00062 20.0 5.9 0.0013 19.0 5.9 1.5 1 0 0 1 1 1 1 C1 domain Herpes_UL92 PF03048.14 CEG46046.1 - 0.19 11.5 1.7 0.4 10.4 1.7 1.4 1 0 0 1 1 1 0 UL92 family UCH PF00443.29 CEG46047.1 - 5.5e-49 167.0 0.0 7e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG46047.1 - 2.3e-09 37.3 1.6 2.4e-08 34.0 1.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEG46047.1 - 0.0015 18.2 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 CEG46047.1 - 0.002 17.7 0.3 0.063 12.7 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Metallophos PF00149.28 CEG46048.1 - 1.4e-20 74.7 1.8 2e-20 74.2 0.9 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 CEG46048.1 - 1.5e-18 67.1 0.1 5.5e-18 65.3 0.1 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 CEG46048.1 - 5.3e-18 65.6 0.1 4e-17 62.8 0.0 2.5 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 CEG46048.1 - 4.8e-05 23.6 0.4 0.0006 20.0 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 CEG46050.1 - 1.7e-82 271.2 2.2 7.1e-21 73.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG46050.1 - 2.5e-12 46.5 0.0 0.092 12.3 0.0 4.6 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEG46050.1 - 1.7e-08 34.3 0.0 1.3 9.0 0.0 5.3 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CEG46050.1 - 5.1e-07 29.5 0.0 0.0027 17.5 0.0 4.4 4 1 0 4 4 4 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CEG46050.1 - 1.2e-05 25.6 2.1 0.91 9.7 0.1 5.7 4 3 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CEG46050.1 - 0.00063 19.8 0.0 6 7.1 0.0 4.5 5 0 0 5 5 5 1 RNA recognition motif RRM_3 PF08777.11 CEG46050.1 - 0.0033 17.4 0.1 4.8 7.3 0.0 4.7 5 0 0 5 5 5 1 RNA binding motif RRM_Rrp7 PF17799.1 CEG46050.1 - 0.0041 16.9 2.1 8.6 6.1 0.0 5.2 5 1 0 5 5 5 1 Rrp7 RRM-like N-terminal domain AA_kinase PF00696.28 CEG46051.1 - 7.5e-35 120.7 2.5 7.5e-35 120.7 2.5 1.7 2 0 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.22 CEG46051.1 - 4e-13 48.7 0.1 3.7e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Vps53_N PF04100.12 CEG46053.1 - 9.2e-99 331.0 5.8 1.7e-98 330.1 5.8 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CEG46053.1 - 2.1e-08 33.8 6.3 2.1e-08 33.8 6.3 2.8 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 CEG46053.1 - 2.5e-05 23.4 1.2 0.00022 20.3 1.2 2.4 1 1 0 1 1 1 1 RINT-1 / TIP-1 family COG7 PF10191.9 CEG46053.1 - 9.1e-05 20.9 7.6 0.00025 19.4 0.2 2.3 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) VPS53_C PF16854.5 CEG46053.1 - 0.038 13.9 0.1 0.038 13.9 0.1 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus FUSC PF04632.12 CEG46053.1 - 0.078 11.5 2.1 0.11 11.0 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.11 CEG46053.1 - 4.9 7.2 8.0 48 4.0 5.9 3.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1656 PF07869.12 CEG46054.1 - 0.59 10.2 4.3 1.7 8.7 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) ATG16 PF08614.11 CEG46055.1 - 3.4e-05 24.2 65.4 0.001 19.3 1.3 5.7 2 2 3 5 5 5 4 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 CEG46055.1 - 0.0027 17.3 7.6 0.0027 17.3 7.6 5.3 2 1 3 5 5 5 2 Leucine zipper RILP PF11461.8 CEG46055.1 - 0.0054 16.9 1.4 0.0054 16.9 1.4 2.9 2 0 0 2 2 2 1 Rab interacting lysosomal protein APG6_N PF17675.1 CEG46055.1 - 0.083 13.4 0.1 0.083 13.4 0.1 6.1 2 1 4 6 6 6 0 Apg6 coiled-coil region HALZ PF02183.18 CEG46055.1 - 0.099 12.9 0.3 0.099 12.9 0.3 7.2 8 1 1 9 9 8 0 Homeobox associated leucine zipper VGPC1_C PF16799.5 CEG46055.1 - 0.19 11.8 5.0 7.4 6.6 0.0 3.9 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 KASH_CCD PF14662.6 CEG46055.1 - 0.35 10.7 63.7 0.65 9.8 9.4 6.0 2 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 CEG46055.1 - 0.5 10.4 59.3 4.8 7.3 0.5 6.3 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 CEG46055.1 - 0.55 10.2 49.7 1 9.4 13.9 5.6 2 1 2 4 4 3 0 Ciliary rootlet component, centrosome cohesion adh_short PF00106.25 CEG46055.1 - 0.8 9.1 4.4 0.91 8.9 0.6 2.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF1664 PF07889.12 CEG46055.1 - 2.5 8.2 34.7 1.5 8.9 2.0 5.9 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 CEG46055.1 - 4.2 6.1 54.3 1.2 8.0 20.9 3.3 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 CEG46055.1 - 4.5 6.7 63.0 0.52 9.7 16.1 4.7 2 1 2 4 4 4 0 Golgin subfamily A member 5 zf-UBR PF02207.20 CEG46056.1 - 3.5e-17 62.3 16.0 3.5e-17 62.3 16.0 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DUF929 PF06053.11 CEG46056.1 - 0.021 14.2 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) CoA_binding PF02629.19 CEG46057.1 - 1.9e-31 108.6 2.4 4.5e-31 107.4 0.5 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CEG46057.1 - 2e-24 86.2 0.1 3.4e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CEG46057.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CEG46057.1 - 0.00076 20.0 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ROK PF00480.20 CEG46062.1 - 2e-52 178.5 0.0 2.6e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 CEG46062.1 - 0.014 14.4 0.2 0.45 9.5 0.4 2.3 2 0 0 2 2 2 0 Glucokinase Cnd1 PF12717.7 CEG46063.1 - 2.1e-45 154.7 7.1 2e-43 148.2 0.1 5.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CEG46063.1 - 4.2e-19 69.0 0.3 1.7e-18 67.0 0.3 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 CEG46063.1 - 0.00016 22.0 1.1 0.057 13.8 0.0 4.1 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CEG46063.1 - 0.004 17.3 1.9 7.5 7.1 0.2 4.8 4 0 0 4 4 4 1 HEAT repeat CLTH PF10607.9 CEG46063.1 - 0.12 12.3 0.6 0.79 9.6 0.2 2.6 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain PSD2 PF07624.11 CEG46063.1 - 0.19 11.5 2.9 0.7 9.7 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1585) C5HCH PF17982.1 CEG46066.1 - 1.6e-05 24.9 3.3 9.4e-05 22.5 3.3 2.4 1 0 0 1 1 1 1 NSD Cys-His rich domain DUF282 PF03380.14 CEG46066.1 - 0.0045 16.9 0.7 0.0045 16.9 0.7 2.3 2 0 0 2 2 2 1 Caenorhabditis protein of unknown function, DUF282 PcfJ PF14284.6 CEG46066.1 - 0.011 15.6 0.3 0.036 13.9 0.3 1.8 1 0 0 1 1 1 0 PcfJ-like protein Methyltransf_28 PF02636.17 CEG46067.1 - 1.9e-35 122.8 0.0 3.1e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 CEG46067.1 - 4.9e-05 24.0 0.0 9.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CEG46067.1 - 0.00099 18.2 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEG46067.1 - 0.0026 18.4 0.0 0.0099 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CNPase PF05881.12 CEG46067.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Methyltransf_23 PF13489.6 CEG46067.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sec1 PF00995.23 CEG46068.1 - 6.4e-98 329.4 0.0 7.4e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TACC_C PF05010.14 CEG46068.1 - 0.0042 16.9 0.1 0.007 16.2 0.1 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma70_r4 PF04545.16 CEG46068.1 - 0.1 12.1 0.1 0.32 10.6 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sdh5 PF03937.16 CEG46069.1 - 2.7e-22 78.5 0.1 3.6e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CbeA_antitoxin PF06154.11 CEG46070.1 - 0.069 13.7 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Peptidase_C15 PF01470.17 CEG46071.1 - 3.7e-18 66.4 0.0 4.8e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase LicD PF04991.13 CEG46076.1 - 8.7e-11 42.4 0.0 3.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 LicD family Med21 PF11221.8 CEG46077.1 - 3.1e-14 53.4 9.4 1.4e-12 48.0 6.4 2.1 1 1 1 2 2 2 2 Subunit 21 of Mediator complex Med9 PF07544.13 CEG46077.1 - 0.034 14.3 2.5 0.073 13.2 2.0 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IFT81_CH PF18383.1 CEG46077.1 - 0.069 13.4 2.5 0.62 10.3 0.1 2.1 1 1 1 2 2 2 0 Intraflagellar transport 81 calponin homology domain CENP-H PF05837.12 CEG46077.1 - 0.32 11.4 7.2 0.59 10.6 7.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Snapin_Pallidin PF14712.6 CEG46078.1 - 2.1e-18 66.5 3.2 5.1e-18 65.3 3.2 1.7 1 0 0 1 1 1 1 Snapin/Pallidin BLOC1S3 PF15753.5 CEG46078.1 - 5.4 7.1 17.7 1.4e+02 2.5 17.8 2.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Cyt-b5 PF00173.28 CEG46079.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RyR PF02026.16 CEG46083.1 - 6e-60 199.4 0.1 3.9e-29 100.7 0.0 3.0 3 0 0 3 3 3 2 RyR domain PKD_channel PF08016.12 CEG46083.1 - 1.7e-37 129.1 11.7 1.2e-26 93.3 12.8 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 CEG46083.1 - 9.1e-12 44.7 12.8 1.8e-11 43.8 12.8 1.4 1 0 0 1 1 1 1 Ion transport protein EGF_2 PF07974.13 CEG46085.1 - 1.4e-10 41.4 42.6 2.6e-06 27.7 6.6 4.4 4 0 0 4 4 4 4 EGF-like domain EGF PF00008.27 CEG46085.1 - 0.026 14.8 34.6 0.097 13.0 3.8 5.1 6 0 0 6 6 6 0 EGF-like domain EGF_alliinase PF04863.13 CEG46085.1 - 0.034 14.6 1.9 0.034 14.6 1.9 5.3 3 2 2 5 5 5 0 Alliinase EGF-like domain EGF_Tenascin PF18720.1 CEG46085.1 - 2 8.6 47.3 1.1 9.4 3.1 4.6 4 0 0 4 4 4 0 Tenascin EGF domain Sas10_Utp3 PF04000.15 CEG46087.1 - 4e-12 46.6 1.2 7.3e-12 45.8 1.2 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2780 PF11075.8 CEG46089.1 - 0.15 12.2 0.6 0.18 12.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) NPP1 PF05630.11 CEG46091.1 - 3.7e-50 170.8 0.0 4.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) RVT_2 PF07727.14 CEG46092.1 - 0.03 14.0 0.0 0.03 14.0 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Reo_P9 PF06043.11 CEG46092.1 - 0.06 12.7 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Reovirus P9-like family FG-GAP_2 PF14312.6 CEG46092.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 FG-GAP repeat Nup54 PF13874.6 CEG46095.1 - 0.059 13.5 0.6 0.076 13.1 0.6 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Peptidase_M20 PF01546.28 CEG46096.1 - 2.4e-22 79.6 0.0 3.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEG46096.1 - 1.2e-11 44.5 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CEG46096.1 - 0.0025 17.5 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CM_2 PF01817.21 CEG46098.1 - 0.047 14.1 0.0 0.059 13.7 0.0 1.3 1 1 0 1 1 1 0 Chorismate mutase type II DUF3106 PF11304.8 CEG46099.1 - 0.035 14.6 2.9 0.042 14.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) TolA_bind_tri PF16331.5 CEG46099.1 - 0.055 13.6 5.0 0.82 9.8 5.0 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation TetR_C_2 PF08361.11 CEG46099.1 - 0.18 11.9 2.5 0.13 12.4 1.2 1.4 1 1 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DUF4407 PF14362.6 CEG46099.1 - 0.76 9.1 4.9 0.77 9.1 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.25 CEG46102.1 - 5e-29 101.2 0.0 3.9e-28 98.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG46102.1 - 2.2e-17 63.4 0.0 3.6e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG46102.1 - 3e-09 37.0 0.0 4.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG46102.1 - 0.0001 21.9 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 CEG46102.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 CEG46102.1 - 0.022 14.7 0.3 0.044 13.7 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CEG46102.1 - 0.035 14.4 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RIO1 PF01163.22 CEG46106.1 - 4.9e-06 26.3 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family AAA PF00004.29 CEG46109.1 - 4.9e-91 302.0 0.0 6.2e-44 149.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG46109.1 - 8.4e-22 76.7 6.5 3.9e-11 42.6 0.7 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEG46109.1 - 8.6e-14 52.3 1.4 7.2e-07 29.7 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.12 CEG46109.1 - 1.9e-12 47.2 0.0 1.2e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG46109.1 - 3.4e-12 46.6 0.1 3.4e-06 27.1 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEG46109.1 - 3.5e-10 40.3 0.0 0.00065 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CEG46109.1 - 1.6e-08 34.2 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CEG46109.1 - 4.5e-08 33.5 0.7 0.0013 19.0 0.1 4.6 3 2 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CEG46109.1 - 6.9e-07 29.5 0.0 0.0028 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEG46109.1 - 8.7e-07 29.3 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 CEG46109.1 - 8.9e-07 29.0 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 CEG46109.1 - 2.3e-06 27.7 0.0 0.0093 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEG46109.1 - 1.7e-05 24.3 0.2 0.03 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CEG46109.1 - 4e-05 24.2 0.0 0.0097 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEG46109.1 - 5.7e-05 22.7 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 CEG46109.1 - 9.9e-05 22.2 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEG46109.1 - 0.00014 22.2 0.0 0.068 13.4 0.0 2.9 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CEG46109.1 - 0.00019 21.3 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 CEG46109.1 - 0.0002 21.0 4.6 1.3 8.5 0.1 4.2 2 2 2 4 4 4 1 AAA domain ATPase PF06745.13 CEG46109.1 - 0.00029 20.2 0.0 0.12 11.7 0.0 2.9 3 0 0 3 3 3 1 KaiC Sigma54_activ_2 PF14532.6 CEG46109.1 - 0.00033 20.8 0.0 0.65 10.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 CEG46109.1 - 0.00075 19.4 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEG46109.1 - 0.0021 17.8 0.0 0.33 10.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 CEG46109.1 - 0.0026 17.5 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CEG46109.1 - 0.0028 17.0 0.0 0.36 10.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 CEG46109.1 - 0.0033 17.9 0.0 1.5 9.3 0.0 2.7 2 1 0 2 2 2 1 ABC transporter TsaE PF02367.17 CEG46109.1 - 0.0057 16.7 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CEG46109.1 - 0.021 14.8 0.6 4.1 7.3 0.0 3.8 4 0 0 4 4 4 0 NACHT domain Zot PF05707.12 CEG46109.1 - 0.036 13.7 0.1 24 4.5 0.1 3.5 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_17 PF13207.6 CEG46109.1 - 0.037 14.4 0.0 3.2 8.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain SKI PF01202.22 CEG46109.1 - 0.041 14.0 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Hydin_ADK PF17213.3 CEG46109.1 - 0.044 14.1 1.0 0.34 11.2 0.0 2.8 4 0 0 4 4 2 0 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 CEG46109.1 - 0.051 13.3 0.4 0.67 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 CEG46109.1 - 0.086 12.3 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein EstA_Ig_like PF18435.1 CEG46109.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain ATP-synt_ab PF00006.25 CEG46109.1 - 0.1 12.2 0.0 1 9.0 0.0 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.17 CEG46109.1 - 0.13 11.3 0.0 0.67 9.0 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Phage_TAC_5 PF08890.11 CEG46109.1 - 0.15 12.1 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC ICAT PF06384.11 CEG46109.1 - 0.15 12.3 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT AAA_6 PF12774.7 CEG46109.1 - 0.27 10.2 1.3 2 7.3 0.0 2.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 CEG46109.1 - 0.4 11.0 1.8 1.7 9.0 0.1 2.8 3 1 0 3 3 2 0 AAA domain TBCC PF07986.12 CEG46110.1 - 1e-13 51.1 0.5 1.3e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Tubulin binding cofactor C DUF4460 PF14687.6 CEG46112.1 - 3.5e-21 75.3 0.0 5.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.31 CEG46112.1 - 0.18 12.0 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 DnaJ domain Kinesin PF00225.23 CEG46115.1 - 2.5e-80 269.9 0.8 6e-80 268.7 0.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG46115.1 - 9.9e-18 64.5 0.4 4.8e-17 62.3 0.1 2.4 2 0 0 2 2 2 1 Microtubule binding DIX PF00778.17 CEG46118.1 - 2.5e-06 27.2 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DIX domain DnaJ PF00226.31 CEG46118.1 - 5.9e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 CEG46118.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 GYF domain 2 DUF3228 PF11539.8 CEG46119.1 - 1.6e-88 295.4 0.0 1.9e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) FAM199X PF15814.5 CEG46120.1 - 0.026 13.6 4.6 0.034 13.2 4.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X DIOX_N PF14226.6 CEG46122.1 - 1.9e-24 86.7 0.0 3.3e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEG46122.1 - 3e-24 85.4 0.0 5.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GSHPx PF00255.19 CEG46123.1 - 2.1e-22 78.8 0.0 2.9e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase MCM_OB PF17207.3 CEG46124.1 - 2.2e-35 121.3 0.1 3.5e-35 120.6 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM PF00493.23 CEG46124.1 - 4e-18 65.3 0.0 7.1e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_N PF14551.6 CEG46124.1 - 1.6e-16 60.8 0.1 1.6e-16 60.8 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 CEG46124.1 - 5.4e-12 46.2 29.3 5.4e-12 46.2 29.3 2.6 1 1 2 3 3 3 1 Mini-chromosome maintenance protein 2 DUF1295 PF06966.12 CEG46124.1 - 7.3e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-Sec23_Sec24 PF04810.15 CEG46124.1 - 0.043 13.9 0.5 0.075 13.1 0.5 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger SO_alpha_A3 PF17806.1 CEG46124.1 - 0.1 12.9 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain zf-TFIIB PF13453.6 CEG46124.1 - 0.1 11.9 1.0 0.21 10.9 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger NTP_transf_3 PF12804.7 CEG46126.1 - 0.0014 19.0 0.0 0.0017 18.8 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Metallophos PF00149.28 CEG46127.1 - 2.1e-24 87.2 2.0 2.3e-24 87.1 0.8 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG46127.1 - 4.6e-17 62.6 0.9 3e-16 60.0 0.0 2.6 2 1 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CEG46127.1 - 7.5e-15 55.3 3.8 1.3e-12 48.1 0.5 2.9 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 CEG46127.1 - 5.4e-05 23.4 0.1 0.0008 19.6 0.1 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VWA_2 PF13519.6 CEG46128.1 - 0.00026 21.6 0.0 0.00065 20.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CEG46128.1 - 0.0035 16.8 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA PF00092.28 CEG46128.1 - 0.0071 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FadA PF09403.10 CEG46128.1 - 0.62 10.6 3.0 1.3 9.5 3.0 1.5 1 0 0 1 1 1 0 Adhesion protein FadA DUF2015 PF09435.10 CEG46131.1 - 0.028 14.3 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Caa3_CtaG PF09678.10 CEG46132.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Methyltransf_16 PF10294.9 CEG46134.1 - 3.3e-17 62.8 0.1 5.7e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CEG46134.1 - 0.0015 18.0 0.2 0.0022 17.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG46134.1 - 0.035 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG46134.1 - 0.18 12.5 0.7 0.8 10.4 0.4 2.0 1 1 1 2 2 2 0 Methyltransferase domain Say1_Mug180 PF10340.9 CEG46135.1 - 0.025 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Mod_r PF07200.13 CEG46136.1 - 0.0057 16.8 2.3 0.0093 16.1 2.3 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Beta-lactamase2 PF13354.6 CEG46136.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Myb_DNA-binding PF00249.31 CEG46137.1 - 8.9e-11 41.8 0.1 2.8e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain GyrB_insert PF18053.1 CEG46137.1 - 0.017 15.0 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain Rap1_C PF11626.8 CEG46137.1 - 0.039 14.0 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myosin_head PF00063.21 CEG46138.1 - 2.4e-219 730.0 4.3 3.5e-219 729.5 4.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEG46138.1 - 1.9e-06 27.2 24.5 0.037 13.8 1.1 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Geminin PF07412.12 CEG46138.1 - 3.1e-05 23.8 2.4 8.2e-05 22.4 2.4 1.7 1 0 0 1 1 1 1 Geminin Myosin_N PF02736.19 CEG46138.1 - 0.0011 18.8 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CEG46138.1 - 0.0054 17.1 0.1 0.026 14.9 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG46138.1 - 0.024 14.9 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 CEG46138.1 - 0.05 13.7 5.6 0.14 12.2 5.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_lid_6 PF17866.1 CEG46138.1 - 0.053 13.7 0.0 2.4 8.4 0.0 3.0 2 0 0 2 2 2 0 AAA lid domain AAA_19 PF13245.6 CEG46138.1 - 0.064 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 CEG46138.1 - 0.2 12.0 9.8 0.076 13.4 5.8 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Rootletin PF15035.6 CEG46138.1 - 0.47 10.5 9.4 1.1 9.3 9.4 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PspA_IM30 PF04012.12 CEG46138.1 - 1.8 8.1 10.6 0.14 11.7 5.1 1.9 2 0 0 2 2 2 0 PspA/IM30 family GIT_CC PF16559.5 CEG46138.1 - 1.9 8.4 5.2 1.9 8.4 2.6 2.5 2 0 0 2 2 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CEG46138.1 - 4.8 7.9 7.8 1.3 9.7 3.5 2.4 2 0 0 2 2 1 0 Initiation control protein YabA TSC22 PF01166.18 CEG46138.1 - 7.3 7.0 8.9 7.8 6.9 4.2 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family FAM76 PF16046.5 CEG46138.1 - 8.3 5.7 8.4 17 4.6 8.4 1.5 1 0 0 1 1 1 0 FAM76 protein Peptidase_S9 PF00326.21 CEG46139.1 - 4e-48 163.7 0.0 6.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CEG46139.1 - 5.3e-47 160.5 6.9 7e-47 160.2 6.9 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain R2K_2 PF18299.1 CEG46139.1 - 0.046 13.6 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 SKA1 PF07160.12 CEG46140.1 - 0.045 13.6 0.2 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Myb_DNA-binding PF00249.31 CEG46141.1 - 2.6e-10 40.3 0.0 4.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Retrotran_gag_2 PF14223.6 CEG46142.1 - 0.0022 17.7 0.4 0.2 11.3 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type Cthe_2159 PF14262.6 CEG46142.1 - 0.023 14.0 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 zf-CCHC PF00098.23 CEG46142.1 - 0.025 14.6 2.4 0.039 14.0 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4413 PF14372.6 CEG46143.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 CEG46143.1 - 0.017 14.9 0.5 0.062 13.1 0.1 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region LPP PF04728.13 CEG46147.1 - 0.0019 18.6 0.8 0.0019 18.6 0.8 2.7 3 1 0 3 3 3 1 Lipoprotein leucine-zipper UPF0231 PF06062.11 CEG46147.1 - 0.39 11.0 10.8 0.17 12.2 7.7 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Trimer_CC PF08954.11 CEG46147.1 - 0.63 9.6 10.3 3.9 7.1 2.4 3.0 2 1 0 2 2 2 0 Trimerisation motif DUF2730 PF10805.8 CEG46147.1 - 0.99 9.5 13.1 0.11 12.6 5.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3209 PF11483.8 CEG46147.1 - 1.1 9.8 7.0 0.26 11.8 3.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) Jnk-SapK_ap_N PF09744.9 CEG46147.1 - 1.8 8.7 23.9 2.8 8.1 2.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 CEG46147.1 - 2.7 8.7 26.4 0.18 12.4 11.8 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 CEG46147.1 - 2.7 8.4 11.0 9 6.8 1.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 CEG46147.1 - 3 8.1 8.2 0.7 10.2 4.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 CEG46147.1 - 7.5 4.3 18.2 8.1 4.2 18.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WW PF00397.26 CEG46148.1 - 5.9e-10 39.1 2.4 9.5e-10 38.4 2.4 1.4 1 0 0 1 1 1 1 WW domain DNA_pol_B_thumb PF14791.6 CEG46148.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta thumb Glyco_hydro_6 PF01341.17 CEG46150.1 - 0.01 15.6 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 zinc_ribbon_4 PF13717.6 CEG46153.1 - 0.079 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Surp PF01805.20 CEG46154.1 - 1.7e-15 56.7 0.2 3.5e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 Surp module SNF2_N PF00176.23 CEG46155.1 - 5.5e-58 196.3 0.1 1e-57 195.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 CEG46155.1 - 6.7e-16 58.6 4.2 8.5e-15 54.9 0.0 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 CEG46155.1 - 1.2e-14 54.6 0.0 3.5e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CEG46155.1 - 2.3e-07 30.5 15.9 0.14 12.5 0.1 8.8 8 1 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 CEG46155.1 - 3.1e-05 24.3 0.6 0.017 15.5 0.2 3.6 3 1 0 3 3 3 1 HEAT repeats ResIII PF04851.15 CEG46155.1 - 8.9e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG46155.1 - 0.0069 16.2 0.0 0.027 14.2 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cnd1 PF12717.7 CEG46155.1 - 0.028 14.5 3.0 8.5 6.4 0.0 5.1 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 TnpV PF14198.6 CEG46155.1 - 0.098 12.6 0.1 7.1 6.7 0.1 2.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV HEAT_EZ PF13513.6 CEG46155.1 - 6.2 7.4 6.6 12 6.5 0.5 4.2 5 0 0 5 5 5 0 HEAT-like repeat PAP2 PF01569.21 CEG46156.1 - 1.3e-16 60.6 6.3 1e-14 54.5 6.3 2.4 1 1 0 1 1 1 1 PAP2 superfamily YfhO PF09586.10 CEG46156.1 - 0.0045 15.3 2.5 0.0045 15.3 2.5 1.5 1 1 0 2 2 2 1 Bacterial membrane protein YfhO 7TM-7TMR_HD PF07698.11 CEG46156.1 - 0.0065 16.2 3.1 0.0065 16.2 3.1 1.9 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase UbiA PF01040.18 CEG46156.1 - 0.013 14.8 3.7 0.013 14.8 3.7 1.9 2 1 0 2 2 2 0 UbiA prenyltransferase family DUF212 PF02681.14 CEG46156.1 - 0.023 14.8 4.2 0.04 14.0 0.1 2.5 2 1 0 3 3 3 0 Divergent PAP2 family PAP2_C PF14360.6 CEG46156.1 - 0.04 14.5 6.1 0.056 14.0 2.2 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal UPF0542 PF15086.6 CEG46156.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 CbiM PF01891.16 CEG46156.1 - 0.75 9.6 7.0 0.054 13.3 1.5 1.7 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region Prefoldin PF02996.17 CEG46157.1 - 0.0016 18.3 7.3 0.032 14.2 1.8 2.5 2 0 0 2 2 2 2 Prefoldin subunit Pox_F16 PF04708.12 CEG46157.1 - 0.007 15.8 0.7 0.0097 15.4 0.7 1.2 1 0 0 1 1 1 1 Poxvirus F16 protein COG2 PF06148.11 CEG46157.1 - 0.0078 16.3 3.4 0.18 11.9 0.4 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Helo_like_N PF17111.5 CEG46157.1 - 0.013 14.9 6.4 0.024 14.0 1.9 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Lebercilin PF15619.6 CEG46157.1 - 0.015 14.9 11.4 0.29 10.8 5.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 CEG46157.1 - 0.016 15.2 7.8 0.72 9.8 3.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 CEG46157.1 - 0.017 15.3 6.1 0.35 11.1 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4349 PF14257.6 CEG46157.1 - 0.022 14.2 4.1 0.13 11.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Mga PF05043.13 CEG46157.1 - 0.026 15.1 2.5 0.039 14.5 0.6 2.0 1 1 1 2 2 2 0 Mga helix-turn-helix domain Spc7 PF08317.11 CEG46157.1 - 0.035 13.0 7.8 0.052 12.4 7.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 CEG46157.1 - 0.039 13.3 2.2 0.088 12.1 2.4 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TMF_DNA_bd PF12329.8 CEG46157.1 - 0.039 13.9 10.9 0.65 10.0 0.3 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lectin_N PF03954.14 CEG46157.1 - 0.039 13.7 3.4 2.5 7.9 1.6 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4559 PF15112.6 CEG46157.1 - 0.047 13.4 4.4 0.061 13.0 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF4140 PF13600.6 CEG46157.1 - 0.054 13.9 4.4 1.1 9.8 1.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 CEG46157.1 - 0.063 13.7 6.9 1.4 9.4 1.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 CEG46157.1 - 0.066 13.6 6.2 0.21 12.0 0.8 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4795 PF16043.5 CEG46157.1 - 0.11 12.0 9.3 0.23 11.0 9.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Sec2p PF06428.11 CEG46157.1 - 0.11 12.4 7.3 0.6 10.1 2.4 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 CEG46157.1 - 0.21 12.2 8.5 2.5 8.8 3.5 2.4 2 0 0 2 2 2 0 SlyX DUF5320 PF17253.2 CEG46157.1 - 0.29 12.2 0.6 1.9 9.6 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) CC2-LZ PF16516.5 CEG46157.1 - 0.31 11.4 9.8 0.58 10.5 3.5 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 CEG46157.1 - 0.39 10.8 6.0 5.1 7.2 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Sbi-IV PF11621.8 CEG46157.1 - 0.59 10.5 5.2 0.47 10.8 2.8 2.1 1 1 1 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Osmo_CC PF08946.10 CEG46157.1 - 1 9.7 8.6 0.48 10.7 5.0 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil FAM76 PF16046.5 CEG46157.1 - 1.3 8.3 9.1 1.8 7.9 8.6 1.6 1 1 0 1 1 1 0 FAM76 protein XhlA PF10779.9 CEG46157.1 - 3.2 8.0 9.7 0.98 9.7 4.0 2.7 2 1 0 2 2 2 0 Haemolysin XhlA YabA PF06156.13 CEG46157.1 - 4.5 8.0 9.1 2.3 8.9 2.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 CEG46157.1 - 5.3 7.6 11.4 2.3 8.7 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 TraS PF10624.9 CEG46159.1 - 0.41 10.6 4.1 0.3 11.0 0.8 2.1 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS TGase_elicitor PF16683.5 CEG46164.1 - 3.4e-135 450.5 2.4 9.6e-73 245.0 0.1 2.3 1 1 1 2 2 2 2 Transglutaminase elicitor TGase_elicitor PF16683.5 CEG46165.1 - 3.6e-164 545.8 0.4 4.5e-164 545.5 0.4 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor CCDC66 PF15236.6 CEG46166.1 - 4.3e-07 29.9 48.1 2.3e-06 27.5 34.6 4.1 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 66 DUF3921 PF13060.6 CEG46166.1 - 0.59 10.2 5.2 4.4 7.4 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) Metallophos PF00149.28 CEG46168.1 - 1.6e-17 64.7 1.1 2.7e-17 63.9 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CEG46168.1 - 2.4e-12 47.5 0.1 5.7e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.10 CEG46168.1 - 0.0011 18.0 0.0 1 8.3 0.1 2.7 3 0 0 3 3 3 2 PhoD-like phosphatase Metallophos_2 PF12850.7 CEG46168.1 - 0.0092 16.2 0.0 0.048 13.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Chromo_2 PF18704.1 CEG46169.1 - 0.0093 16.2 0.0 0.0097 16.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 ATG11 PF10377.9 CEG46170.1 - 4.1e-21 75.4 0.0 2e-20 73.2 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 CEG46170.1 - 8.1e-13 48.2 2.3 8.1e-13 48.2 2.3 4.1 3 1 0 4 4 4 2 Autophagy protein Apg17 NGF PF00243.18 CEG46170.1 - 0.023 14.9 0.0 0.072 13.4 0.0 1.8 1 0 0 1 1 1 0 Nerve growth factor family T6SS_TssG PF06996.11 CEG46170.1 - 0.029 13.6 0.8 0.26 10.5 0.2 2.4 2 0 0 2 2 2 0 Type VI secretion, TssG Selenoprotein_S PF06936.11 CEG46170.1 - 0.074 12.9 0.2 0.28 11.0 0.2 2.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Spore_III_AB PF09548.10 CEG46170.1 - 0.14 12.3 3.8 2.8 8.0 0.4 3.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3763 PF12592.8 CEG46170.1 - 0.75 9.9 4.4 4.8 7.3 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) Nup54 PF13874.6 CEG46170.1 - 2.6 8.2 24.7 1.9 8.6 0.0 5.4 4 1 0 4 4 4 0 Nucleoporin complex subunit 54 Exo_endo_phos PF03372.23 CEG46171.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_2 PF00002.24 CEG46171.1 - 0.0003 20.2 10.4 0.00041 19.7 10.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Rab5ip PF07019.12 CEG46171.1 - 0.065 13.8 0.6 0.47 11.1 1.1 2.2 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) 7tm_1 PF00001.21 CEG46171.1 - 5.5 6.2 12.9 8.7 5.6 12.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PrmA PF06325.13 CEG46173.1 - 7.9e-12 45.2 0.1 1.7e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEG46173.1 - 4.5e-08 33.7 0.0 1e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG46173.1 - 8.5e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG46173.1 - 3.2e-06 26.8 0.1 5.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CEG46173.1 - 1.1e-05 25.3 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CEG46173.1 - 1.6e-05 24.8 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 CEG46173.1 - 3.3e-05 23.9 0.1 5.7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG46173.1 - 5.7e-05 22.9 0.0 0.00017 21.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEG46173.1 - 0.00029 19.9 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CEG46173.1 - 0.00077 18.8 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 CEG46173.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 CEG46173.1 - 0.003 18.5 0.0 0.0059 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEG46173.1 - 0.004 16.9 0.1 0.0076 16.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 CEG46173.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 CEG46173.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 CEG46173.1 - 0.059 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CEG46173.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_anti-codon PF01336.25 CEG46174.1 - 0.0034 17.3 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 CEG46174.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 2-oxoacid_dh PF00198.23 CEG46177.1 - 6.7e-56 189.3 0.0 8.5e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEG46177.1 - 1.4e-15 56.9 0.5 4.2e-15 55.3 0.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEG46177.1 - 4.6e-14 52.5 1.4 6.1e-14 52.1 0.2 1.9 2 0 0 2 2 2 1 e3 binding domain HlyD_3 PF13437.6 CEG46177.1 - 0.0048 17.6 0.3 0.028 15.1 0.1 2.3 2 0 0 2 2 2 1 HlyD family secretion protein DUF515 PF04415.12 CEG46177.1 - 0.0069 14.8 0.1 0.012 14.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF515) SIS_2 PF13580.6 CEG46177.1 - 0.069 13.2 0.0 0.86 9.6 0.0 2.6 3 0 0 3 3 3 0 SIS domain ELFV_dehydrog PF00208.21 CEG46178.1 - 7e-55 186.4 0.0 1e-54 185.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEG46178.1 - 1.1e-18 66.3 0.0 4.5e-10 37.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CEG46178.1 - 0.0041 17.0 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain zf-C3HC PF07967.13 CEG46178.1 - 0.035 14.1 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like Hydrolase PF00702.26 CEG46179.1 - 0.0045 17.3 0.0 0.0053 17.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FYVE PF01363.21 CEG46180.1 - 5e-15 55.4 11.0 8.8e-15 54.6 11.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 CEG46180.1 - 1.5e-07 32.1 0.0 2.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CEG46180.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain PI3_PI4_kinase PF00454.27 CEG46181.1 - 1e-49 169.6 0.0 1e-34 120.5 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEG46181.1 - 4e-48 163.3 0.6 6.1e-48 162.7 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CEG46181.1 - 2.7e-26 92.2 0.0 4.9e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CEG46181.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) UPRTase PF14681.6 CEG46186.1 - 5.9e-25 87.9 0.0 8.1e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase EF-hand_7 PF13499.6 CEG46187.1 - 7e-32 109.7 26.3 6.3e-11 42.6 1.6 6.1 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 CEG46187.1 - 3.6e-28 95.0 19.1 8e-05 21.9 0.7 7.0 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CEG46187.1 - 4.2e-27 91.7 14.3 0.00017 21.2 0.2 7.9 7 0 0 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 CEG46187.1 - 1.2e-21 76.3 16.1 1.8e-07 30.9 0.5 7.4 6 1 1 7 7 7 4 EF-hand domain pair EF-hand_5 PF13202.6 CEG46187.1 - 6.2e-13 47.6 24.2 0.00066 19.1 0.3 6.9 7 0 0 7 7 7 5 EF hand SPARC_Ca_bdg PF10591.9 CEG46187.1 - 2.9e-05 24.4 16.3 0.0075 16.6 0.2 5.0 4 0 0 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEG46187.1 - 0.0037 17.2 8.9 4 7.4 0.0 4.8 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEG46187.1 - 0.0088 16.3 1.1 2.6 8.4 0.0 3.2 2 0 0 2 2 2 1 EF-hand domain Fer4_24 PF18109.1 CEG46187.1 - 7 7.0 6.9 16 5.9 1.3 2.7 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain MBOAT PF03062.19 CEG46188.1 - 1e-17 64.6 3.6 2e-17 63.6 3.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF4281 PF14108.6 CEG46188.1 - 0.0017 18.7 2.3 0.027 14.8 0.7 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4281) fn3 PF00041.21 CEG46190.1 - 8.8e-11 42.0 0.2 0.0025 18.1 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Pyrophosphatase PF00719.19 CEG46193.1 - 1.4e-43 148.5 0.3 3e-43 147.4 0.3 1.6 1 0 0 1 1 1 1 Inorganic pyrophosphatase PH PF00169.29 CEG46193.1 - 2.4e-08 34.4 0.0 4.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 CEG46193.1 - 1.8e-06 27.4 0.8 0.0001 21.9 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CEG46193.1 - 8.8e-06 26.1 0.1 2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG46193.1 - 2.7e-05 23.4 0.6 0.00069 19.0 0.4 2.6 2 0 0 2 2 2 1 EF hand Glyco_transf_8C PF08437.10 CEG46193.1 - 0.027 14.5 0.5 0.91 9.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal EF-hand_8 PF13833.6 CEG46193.1 - 0.054 13.4 0.9 0.5 10.2 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain pair Malic_M PF03949.15 CEG46193.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain CCDC144C PF14915.6 CEG46193.1 - 0.19 10.8 0.1 0.42 9.7 0.1 1.5 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region PIP5K PF01504.18 CEG46194.1 - 1.1e-88 297.1 0.0 1.6e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PGAP1 PF07819.13 CEG46195.1 - 0.00031 20.5 0.0 0.0008 19.2 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CEG46195.1 - 0.031 13.8 0.3 0.091 12.3 0.3 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Pkinase PF00069.25 CEG46199.1 - 1.8e-65 220.9 0.0 2.2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46199.1 - 2.6e-31 108.9 0.0 3.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG46199.1 - 0.0049 15.9 0.1 0.0075 15.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG46199.1 - 0.043 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG46199.1 - 0.079 12.9 0.1 0.4 10.6 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1108 PF06531.11 CEG46199.1 - 0.096 13.0 0.9 0.19 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) FTA2 PF13095.6 CEG46199.1 - 0.23 11.0 0.4 0.62 9.7 0.1 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DIX PF00778.17 CEG46200.1 - 2.4e-08 33.7 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 DIX domain LRR_4 PF12799.7 CEG46201.1 - 7.5e-47 156.5 44.5 1.6e-09 37.9 1.9 7.2 2 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG46201.1 - 2.1e-26 91.5 28.4 1.6e-06 27.8 0.4 5.8 2 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 CEG46201.1 - 2.3e-21 76.1 17.1 2.4e-11 43.5 0.3 4.2 1 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CEG46201.1 - 3.8e-07 29.7 21.7 4.5 8.2 0.1 10.1 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 CEG46201.1 - 0.0016 18.3 28.0 1.5 9.1 0.1 9.4 10 1 1 11 11 11 2 Leucine Rich repeat Rieske_2 PF13806.6 CEG46202.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.3 1 1 0 1 1 1 0 Rieske-like [2Fe-2S] domain Bacillus_PapR PF05968.11 CEG46202.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacillus PapR protein GCV_T PF01571.21 CEG46203.1 - 5e-82 275.1 0.0 6.6e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CEG46203.1 - 1.9e-21 75.8 0.1 3.8e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 CEG46203.1 - 0.059 13.3 0.3 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) DUF3759 PF12585.8 CEG46203.1 - 0.089 12.8 0.8 0.18 11.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) SPOB_ab PF14682.6 CEG46203.1 - 0.09 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal ANAPC8 PF04049.13 CEG46205.1 - 0.03 14.4 0.4 0.03 14.4 0.4 2.4 2 1 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 WD40 PF00400.32 CEG46207.1 - 7.3e-06 26.6 5.7 0.11 13.4 0.2 6.1 6 1 0 6 6 6 2 WD domain, G-beta repeat Aa_trans PF01490.18 CEG46213.1 - 3.4e-14 52.4 30.2 1.5e-13 50.3 30.2 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein fn3_3 PF14686.6 CEG46213.1 - 0.01 15.6 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Pkinase PF00069.25 CEG46214.1 - 7e-69 232.1 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46214.1 - 5.3e-27 94.7 0.0 7.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG46214.1 - 1.6e-06 27.7 0.3 3e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG46214.1 - 0.00011 22.3 0.1 0.0018 18.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEG46214.1 - 0.0018 17.7 0.1 0.0058 16.0 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG46214.1 - 0.031 13.1 0.1 0.095 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CEG46214.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CEG46214.1 - 0.097 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family UQ_con PF00179.26 CEG46216.1 - 6.1e-35 119.9 0.0 1.2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PRP21_like_P PF12230.8 CEG46216.1 - 0.39 10.6 8.8 0.55 10.1 8.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein HSF_DNA-bind PF00447.17 CEG46219.1 - 1.8e-29 102.2 0.0 3.5e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding AAA_22 PF13401.6 CEG46220.1 - 1.1e-09 38.6 0.0 4.6e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG46220.1 - 9.6e-07 29.3 0.2 8.1e-06 26.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CEG46220.1 - 0.00095 18.7 0.0 0.013 15.0 0.0 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CEG46220.1 - 0.0078 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEG46220.1 - 0.0098 16.4 0.0 0.03 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG46220.1 - 0.012 15.7 0.1 0.22 11.7 0.0 2.9 2 1 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CEG46220.1 - 0.014 15.3 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_lid_10 PF17872.1 CEG46220.1 - 0.015 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_11 PF13086.6 CEG46220.1 - 0.015 15.1 1.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG46220.1 - 0.032 14.7 0.1 0.28 11.6 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 CEG46220.1 - 0.037 14.1 0.2 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 CEG46220.1 - 0.04 13.3 0.8 0.86 8.9 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family Glyco_hydro_8 PF01270.17 CEG46220.1 - 0.069 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 AAA_24 PF13479.6 CEG46220.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEG46220.1 - 0.075 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 CEG46220.1 - 0.086 12.2 2.4 3 7.2 0.0 3.0 4 0 0 4 4 4 0 Bacterial TniB protein AAA_5 PF07728.14 CEG46220.1 - 0.18 11.8 0.4 0.62 10.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) UPF0176_N PF17773.1 CEG46221.1 - 5.1e-17 62.0 0.0 8.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 CEG46221.1 - 2.6e-10 40.7 0.0 4.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 CEG46221.1 - 8.2e-05 22.9 1.4 0.00019 21.7 1.4 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal DUF2430 PF10353.9 CEG46221.1 - 0.00061 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2430) zinc_ribbon_9 PF14369.6 CEG46221.1 - 0.1 12.8 1.7 2.2 8.6 0.0 2.4 1 1 1 2 2 2 0 zinc-ribbon DZR PF12773.7 CEG46221.1 - 0.14 12.2 1.8 0.33 11.0 1.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Leu_Phe_trans PF03588.14 CEG46222.1 - 2.2e-21 76.1 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase RasGEF PF00617.19 CEG46223.1 - 7.7e-43 146.7 0.3 7.7e-43 146.7 0.3 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEG46223.1 - 2.8e-16 59.7 0.6 9.2e-16 58.0 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SPACA7 PF15307.6 CEG46223.1 - 0.065 13.5 0.8 6.8 7.0 0.0 3.6 3 0 0 3 3 3 0 Sperm acrosome-associated protein 7 SesA PF17107.5 CEG46223.1 - 1.7 8.9 5.7 33 4.7 1.6 3.7 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Rep_fac-A_C PF08646.10 CEG46224.1 - 2.3e-07 30.7 0.0 2.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Replication factor-A C terminal domain RMI1_C PF16099.5 CEG46224.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold CDC24_OB3 PF17244.2 CEG46224.1 - 0.068 12.9 0.2 0.092 12.4 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Pkinase PF00069.25 CEG46225.1 - 5.9e-74 248.7 0.0 9.6e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46225.1 - 1.5e-39 135.9 0.0 2.4e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CEG46225.1 - 5.7e-37 125.7 0.5 4.1e-20 71.7 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CEG46225.1 - 1.9e-07 30.7 0.0 6.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEG46225.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0182 PF03699.13 CEG46229.1 - 0.013 13.7 9.7 0.015 13.4 9.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Beta_elim_lyase PF01212.21 CEG46232.1 - 6.6e-61 206.2 0.1 7.2e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEG46232.1 - 2.9e-08 33.3 0.0 3.4e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG46232.1 - 7e-07 28.5 0.0 9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 CEG46232.1 - 0.00045 19.0 0.0 0.0007 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CEG46232.1 - 0.019 13.5 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEG46232.1 - 0.065 12.5 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DEAD PF00270.29 CEG46233.1 - 3.5e-48 163.7 0.0 5.1e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG46233.1 - 4.1e-31 107.6 0.0 9.8e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_4 PF12799.7 CEG46234.1 - 4.5e-20 71.4 24.6 1.3e-07 31.8 6.5 6.1 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG46234.1 - 9.7e-13 47.7 17.7 6.3e-06 25.9 0.4 4.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CEG46234.1 - 3.5e-09 36.4 13.7 8.1e-05 22.2 4.6 3.4 1 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 CEG46234.1 - 0.00099 19.3 19.5 4.4 8.2 0.4 7.9 5 2 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 CEG46234.1 - 0.11 12.6 18.4 7.2 6.9 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich repeat IGR PF09597.10 CEG46234.1 - 0.18 11.9 0.7 1.5 9.0 0.2 2.6 2 1 1 3 3 3 0 IGR protein motif Semialdhyde_dhC PF02774.18 CEG46235.1 - 9.4e-47 159.5 0.0 1.3e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CEG46235.1 - 2.5e-25 89.3 0.0 6.6e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CBP_BcsQ PF06564.12 CEG46235.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ FimH_man-bind PF09160.10 CEG46238.1 - 0.15 11.8 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 FimH, mannose binding Rho_GDI PF02115.17 CEG46239.1 - 6.5e-44 150.0 0.0 7.7e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ceramidase_alk PF04734.13 CEG46239.1 - 0.051 12.2 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Bystin PF05291.11 CEG46240.1 - 1.2e-128 428.5 0.9 2.1e-128 427.7 0.9 1.4 1 0 0 1 1 1 1 Bystin NUC130_3NT PF08158.12 CEG46240.1 - 0.046 14.0 0.2 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 NUC130/3NT domain DUF1681 PF07933.14 CEG46241.1 - 2.3e-39 134.5 0.0 2.8e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Agenet PF05641.12 CEG46251.1 - 0.0004 20.8 0.2 0.78 10.3 0.1 2.7 2 0 0 2 2 2 2 Agenet domain MG4 PF17789.1 CEG46251.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.9 1 1 0 1 1 1 0 Macroglobulin domain MG4 GSH_synth_ATP PF03917.17 CEG46252.1 - 1.3e-125 419.1 0.0 1.6e-125 418.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CEG46252.1 - 1.5e-36 125.0 0.1 3e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Pex24p PF06398.11 CEG46253.1 - 1.7e-09 37.1 7.3 3.3e-09 36.2 7.3 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Prefoldin PF02996.17 CEG46253.1 - 0.2 11.6 2.7 0.41 10.6 0.0 2.8 3 0 0 3 3 3 0 Prefoldin subunit Med19 PF10278.9 CEG46253.1 - 2.5 8.0 7.7 0.1 12.5 0.9 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Lebercilin PF15619.6 CEG46254.1 - 0.081 12.6 10.5 0.019 14.6 2.6 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DHHC PF01529.20 CEG46256.1 - 3.2e-32 111.5 8.8 3.2e-32 111.5 8.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase ARL2_Bind_BART PF11527.8 CEG46257.1 - 1.2e-23 83.5 7.4 1.4e-23 83.2 7.4 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Tubulin PF00091.25 CEG46259.1 - 6e-65 219.1 0.0 7.4e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG46259.1 - 1.5e-08 34.8 0.1 2.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEG46259.1 - 0.012 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 CEG46260.1 - 4.2e-66 222.9 0.0 1.2e-65 221.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG46260.1 - 3e-12 46.8 0.2 5.5e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEG46260.1 - 0.00048 19.8 0.0 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain PS_Dcarbxylase PF02666.15 CEG46262.1 - 2e-59 200.5 0.0 2.9e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PS_Dcarbxylase PF02666.15 CEG46263.1 - 1.6e-41 142.1 0.1 1.7e-39 135.5 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase DDOST_48kD PF03345.14 CEG46264.1 - 7.1e-124 413.8 0.2 8.1e-124 413.6 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.9 CEG46264.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DUF4350 PF14258.6 CEG46264.1 - 0.098 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Aldedh PF00171.22 CEG46267.1 - 2.5e-68 230.7 0.0 3.1e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ARL2_Bind_BART PF11527.8 CEG46268.1 - 1.4e-20 73.5 6.1 2.2e-20 72.9 6.1 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF2564 PF10819.8 CEG46268.1 - 0.1 13.0 3.4 0.81 10.1 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) SWIRM PF04433.17 CEG46269.1 - 2e-29 101.7 0.4 9.8e-29 99.6 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CEG46269.1 - 3.7e-14 52.4 6.0 9.8e-14 51.1 6.0 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CEG46269.1 - 7.4e-05 22.9 0.1 0.00013 22.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF815 PF05673.13 CEG46269.1 - 0.0047 16.1 0.1 0.012 14.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Myb_DNA-bind_6 PF13921.6 CEG46269.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF269 PF03270.13 CEG46270.1 - 0.078 13.1 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF269 Aldedh PF00171.22 CEG46271.1 - 1.7e-52 178.5 0.6 2e-52 178.3 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RVT_1 PF00078.27 CEG46272.1 - 3.7e-07 29.9 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rft-1 PF04506.13 CEG46276.1 - 1.1e-99 334.5 27.5 1.5e-99 334.1 27.5 1.0 1 0 0 1 1 1 1 Rft protein PspC PF04024.12 CEG46276.1 - 0.098 12.5 1.1 0.7 9.8 1.1 2.6 1 0 0 1 1 1 0 PspC domain ELP6 PF09807.9 CEG46277.1 - 1.3e-35 123.0 0.1 2.9e-18 66.2 0.2 2.0 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 CEG46277.1 - 3.4e-05 23.5 0.1 4.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 CEG46277.1 - 0.0032 16.9 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 KaiC TEX13 PF15186.6 CEG46277.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Pkinase PF00069.25 CEG46278.1 - 1.5e-61 208.1 0.0 1.9e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46278.1 - 1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG46278.1 - 2.2e-06 27.2 0.0 4.6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG46278.1 - 6.7e-05 22.3 0.1 0.0001 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG46278.1 - 0.00015 21.8 0.1 0.37 10.7 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG46278.1 - 0.0007 18.6 0.2 0.001 18.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG46278.1 - 0.0027 16.6 0.0 0.0044 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CEG46278.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CEG46278.1 - 0.047 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SpoU_methylase PF00588.19 CEG46279.1 - 1.2e-24 87.1 0.0 2.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Cullin_binding PF03556.15 CEG46279.1 - 0.017 15.5 2.2 0.35 11.3 0.5 3.7 3 0 0 3 3 3 0 Cullin binding HTH_20 PF12840.7 CEG46279.1 - 0.037 14.1 3.1 0.19 11.8 0.0 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain TAF1_subA PF14929.6 CEG46279.1 - 0.06 12.8 5.9 0.017 14.5 0.9 2.6 3 0 0 3 3 3 0 TAF RNA Polymerase I subunit A Phage_TTP_13 PF16463.5 CEG46279.1 - 0.23 11.0 1.0 10 5.6 0.0 2.8 3 0 0 3 3 3 0 Phage tail tube protein family TFIIS_C PF01096.18 CEG46280.1 - 8.6e-19 67.1 5.7 8.6e-19 67.1 5.7 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CEG46280.1 - 7.6e-09 35.3 1.5 7.6e-09 35.3 1.5 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CEG46280.1 - 7.5e-05 22.6 1.4 7.5e-05 22.6 1.4 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zf-RRPl_C4 PF17026.5 CEG46280.1 - 0.006 16.7 2.9 0.0081 16.3 2.9 1.3 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-ribbon_3 PF13248.6 CEG46280.1 - 0.0094 15.3 12.0 0.11 12.0 0.1 3.8 4 0 0 4 4 4 2 zinc-ribbon domain Nudix_N_2 PF14803.6 CEG46280.1 - 0.011 15.7 0.5 0.011 15.7 0.5 2.9 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.7 CEG46280.1 - 0.072 13.1 10.7 1.6 8.8 5.0 3.1 1 1 1 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 CEG46280.1 - 0.12 12.4 3.6 0.58 10.2 0.0 3.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Auto_anti-p27 PF06677.12 CEG46280.1 - 0.15 12.3 1.1 0.15 12.3 1.1 3.0 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 CEG46280.1 - 0.22 11.6 10.2 4.4 7.5 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain IBR PF01485.21 CEG46280.1 - 0.4 10.9 11.0 6.8e+02 0.6 11.0 2.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 CEG46280.1 - 0.5 10.6 10.0 1.4 9.2 1.1 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DNA_primase_lrg PF04104.14 CEG46280.1 - 0.51 9.7 4.3 2.7 7.3 0.8 2.0 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Terminase_GpA PF05876.12 CEG46280.1 - 0.51 8.8 7.1 0.038 12.5 2.3 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_2 PF13240.6 CEG46280.1 - 0.59 9.9 0.2 0.59 9.9 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-Dof PF02701.15 CEG46280.1 - 0.67 10.1 12.0 0.49 10.6 5.2 2.7 3 0 0 3 3 3 0 Dof domain, zinc finger zf-LITAF-like PF10601.9 CEG46280.1 - 0.96 9.8 8.6 6.3 7.1 0.1 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain zinc_ribbon_4 PF13717.6 CEG46280.1 - 1 9.4 13.9 7.1 6.7 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CEG46280.1 - 1 9.3 7.6 4.5 7.3 0.1 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_15 PF17032.5 CEG46280.1 - 1.2 9.9 11.2 2.8 8.8 4.0 3.0 2 1 0 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 CEG46280.1 - 1.6 8.8 10.6 0.95 9.5 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-ACC PF17848.1 CEG46280.1 - 2 8.6 0.1 2 8.6 0.1 3.6 4 0 0 4 4 3 0 Acetyl-coA carboxylase zinc finger domain DUF3797 PF12677.7 CEG46280.1 - 2.9 7.9 8.3 7.8 6.5 0.1 2.9 3 1 0 3 3 2 0 Domain of unknown function (DUF3797) PHD PF00628.29 CEG46280.1 - 2.9 7.9 9.4 7.9 6.5 0.2 3.1 2 1 1 3 3 3 0 PHD-finger Zn_ribbon_SprT PF17283.2 CEG46280.1 - 4.3 7.3 10.5 22 5.0 0.6 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain HypA PF01155.19 CEG46280.1 - 5.5 7.1 8.3 3.4 7.7 3.3 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DEAD PF00270.29 CEG46281.1 - 1.2e-18 67.5 0.0 2.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CEG46281.1 - 2.2e-18 66.7 4.3 8.5e-18 64.8 4.3 2.1 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 CEG46281.1 - 8.3e-16 58.3 0.0 1.9e-14 53.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG46281.1 - 0.02 14.9 0.0 0.058 13.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peripla_BP_4 PF13407.6 CEG46281.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain HSP70 PF00012.20 CEG46282.1 - 1e-136 456.6 1.7 1.2e-136 456.4 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG46282.1 - 2e-15 56.5 2.0 2.1e-14 53.1 1.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CEG46282.1 - 0.0027 17.0 0.2 0.0086 15.3 0.2 1.9 1 1 0 1 1 1 1 StbA protein Rod_C PF10493.9 CEG46283.1 - 7.2e-25 87.4 6.5 7.2e-25 87.4 6.5 2.4 2 0 0 2 2 2 1 Rough deal protein C-terminal region MRP-S22 PF10245.9 CEG46283.1 - 0.0072 16.1 1.3 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S22 MTES_1575 PF18741.1 CEG46283.1 - 0.023 14.8 0.0 0.29 11.3 0.0 2.8 1 1 0 2 2 2 0 REase_MTES_1575 RFC1 PF08519.12 CEG46285.1 - 0.0025 18.0 0.9 0.0025 18.0 0.9 3.2 2 1 0 2 2 2 1 Replication factor RFC1 C terminal domain HMGL-like PF00682.19 CEG46285.1 - 0.017 14.7 14.9 0.19 11.2 1.1 2.9 2 1 1 3 3 3 0 HMGL-like Vac14_Fab1_bd PF12755.7 CEG46285.1 - 0.029 14.9 0.2 0.27 11.8 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region PP2C PF00481.21 CEG46286.1 - 2.2e-66 224.2 0.0 2.4e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG46286.1 - 1.3e-07 31.5 0.0 3.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C GvpD PF07088.11 CEG46286.1 - 0.059 12.0 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein MADF_DNA_bdg PF10545.9 CEG46287.1 - 0.13 12.6 1.3 0.29 11.5 1.3 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Bacillus_HBL PF05791.11 CEG46291.1 - 0.091 12.6 0.2 0.95 9.3 0.0 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Cation_efflux PF01545.21 CEG46292.1 - 7e-27 94.5 2.5 1e-26 93.9 2.5 1.3 1 0 0 1 1 1 1 Cation efflux family DRY_EERY PF09750.9 CEG46294.1 - 0.51 10.6 0.1 0.51 10.6 0.1 2.3 2 1 0 2 2 2 0 Alternative splicing regulator SRP-alpha_N PF04086.13 CEG46294.1 - 0.51 10.2 17.6 0.69 9.8 17.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 CEG46294.1 - 3.4 6.2 6.6 3.8 6.1 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HGTP_anticodon2 PF12745.7 CEG46294.1 - 6.9 6.1 10.8 12 5.3 10.7 1.4 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs RVT_2 PF07727.14 CEG46295.1 - 5.6e-41 140.8 0.2 7.1e-41 140.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG46295.1 - 1.5e-05 24.6 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1069 PF06370.11 CEG46296.1 - 0.063 12.9 0.0 0.068 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Complex1_LYR PF05347.15 CEG46297.1 - 5.5e-10 39.1 1.1 5.5e-10 39.1 1.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) adh_short PF00106.25 CEG46298.1 - 2.4e-52 177.3 0.1 3e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG46298.1 - 5.5e-35 121.0 0.0 7.1e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG46298.1 - 5.7e-14 52.4 0.2 9.1e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG46298.1 - 0.017 14.6 0.0 0.06 12.8 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 CEG46298.1 - 0.066 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_4 PF12799.7 CEG46301.1 - 1.5e-18 66.6 19.4 0.00013 22.3 0.2 5.4 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG46301.1 - 1.5e-15 57.1 10.3 1.1e-11 44.6 2.0 3.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 CEG46301.1 - 1.4e-11 44.0 16.5 1.3e-05 24.8 3.4 4.4 3 2 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CEG46301.1 - 7.3e-10 38.1 12.8 0.18 12.0 0.0 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 CEG46301.1 - 0.00081 19.6 10.1 5.5 7.9 0.1 6.3 5 3 1 6 6 6 2 Leucine Rich Repeat Cpn60_TCP1 PF00118.24 CEG46302.1 - 4.7e-154 513.6 12.4 5.4e-154 513.5 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Condensin2nSMC PF12422.8 CEG46303.1 - 1.7e-49 167.8 1.8 6.7e-49 165.9 0.1 2.8 4 0 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 CEG46303.1 - 0.00028 20.9 0.1 38 4.9 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CEG46303.1 - 0.0048 17.3 0.0 1.1 9.7 0.0 3.3 1 1 1 2 2 2 1 HEAT repeats fn3_2 PF16893.5 CEG46303.1 - 0.16 12.2 0.1 0.42 10.8 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain MeaB PF03308.16 CEG46305.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 CEG46305.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 CEG46305.1 - 0.035 14.1 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RHSP PF07999.11 CEG46305.1 - 0.043 12.6 0.0 0.55 9.0 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein IstB_IS21 PF01695.17 CEG46305.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CEG46305.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CEG46305.1 - 0.16 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CEG46305.1 - 0.21 10.6 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 CEG46305.1 - 0.23 11.4 0.0 0.3 11.0 0.0 1.1 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 CEG46305.1 - 0.27 10.5 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3173 PF11372.8 CEG46307.1 - 0.038 13.8 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) RVT_2 PF07727.14 CEG46308.1 - 0.0063 16.2 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mog1 PF04603.12 CEG46313.1 - 4.3e-39 134.0 0.1 5.5e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein BT1 PF03092.16 CEG46314.1 - 4.7e-13 48.2 5.6 3.9e-11 41.9 0.3 3.2 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 CEG46314.1 - 0.00044 19.4 0.1 0.00044 19.4 0.1 2.3 2 1 1 3 3 3 1 PUCC protein DUF2207 PF09972.9 CEG46314.1 - 0.89 8.2 7.6 2.1 7.0 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) LMWPc PF01451.21 CEG46316.1 - 6.8e-18 65.4 0.1 9.4e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MULE PF10551.9 CEG46318.1 - 2.8e-11 43.7 0.2 1.9e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain mRNA_stabil PF13929.6 CEG46318.1 - 0.00063 18.8 0.3 0.00086 18.4 0.3 1.2 1 0 0 1 1 1 1 mRNA stabilisation Transposase_mut PF00872.18 CEG46318.1 - 0.069 12.0 0.1 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF4471 PF14740.6 CEG46319.1 - 5.9e-80 268.8 2.9 7.9e-80 268.3 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 CEG46319.1 - 8.6e-22 77.2 0.0 1.6e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Glyco_hydro_18 PF00704.28 CEG46320.1 - 5.6e-30 105.1 0.2 7.6e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SSB PF00436.25 CEG46320.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Single-strand binding protein family RWP-RK PF02042.15 CEG46321.1 - 2.7e-17 62.5 0.3 5.4e-17 61.5 0.3 1.5 1 0 0 1 1 1 1 RWP-RK domain Hira PF07569.11 CEG46322.1 - 1.8e-38 132.5 0.0 4.5e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 CEG46322.1 - 1.9e-33 113.9 19.3 6.9e-09 36.2 0.1 8.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46322.1 - 9.8e-16 57.8 1.9 0.032 14.5 0.0 5.8 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 CEG46322.1 - 0.049 12.7 0.0 3.2 6.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) PD40 PF07676.12 CEG46322.1 - 0.12 12.4 0.1 24 5.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_C97 PF05903.14 CEG46323.1 - 2.4e-27 95.6 0.0 3.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Med26 PF08711.11 CEG46328.1 - 5.2e-14 52.0 0.6 5.2e-14 52.0 0.6 2.7 2 1 0 2 2 2 1 TFIIS helical bundle-like domain DEK_C PF08766.11 CEG46328.1 - 4.6e-08 32.9 2.1 9e-08 31.9 2.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain LacI PF00356.21 CEG46328.1 - 0.26 11.1 3.2 3.1 7.7 0.2 3.4 2 1 1 3 3 3 0 Bacterial regulatory proteins, lacI family His_Phos_2 PF00328.22 CEG46330.1 - 4.8e-19 69.0 0.1 3.8e-15 56.1 0.1 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) FANCI_S3 PF14677.6 CEG46330.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 BTB_2 PF02214.22 CEG46331.1 - 9.6e-11 41.9 0.4 5.7e-10 39.4 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain Kazal_1 PF00050.21 CEG46332.1 - 2.3e-22 78.7 23.5 3.5e-08 33.3 3.8 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CEG46332.1 - 1e-21 76.8 24.7 1.4e-08 34.7 4.2 3.6 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain DUF3081 PF11280.8 CEG46332.1 - 0.038 13.8 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Glyco_hydro_63 PF03200.16 CEG46333.1 - 2e-169 564.5 1.4 1.6e-107 360.3 0.7 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CEG46333.1 - 5.4e-33 115.0 0.0 9.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CEG46333.1 - 0.015 14.1 0.2 0.044 12.6 0.1 1.8 2 0 0 2 2 2 0 Trehalase OST3_OST6 PF04756.13 CEG46334.1 - 5.4e-66 222.9 0.5 7.4e-66 222.5 0.5 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Cyd_oper_YbgE PF09600.10 CEG46334.1 - 0.073 13.5 2.9 5.3 7.5 2.1 2.6 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) PHO4 PF01384.20 CEG46334.1 - 1.4 7.9 4.0 1.1 8.2 0.2 2.0 1 1 0 2 2 2 0 Phosphate transporter family ETRAMP PF09716.10 CEG46334.1 - 1.9 8.6 4.1 3.8 7.6 0.3 2.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1336 PF07059.12 CEG46335.1 - 8.5e-67 225.5 0.0 1.3e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 CEG46335.1 - 4.5e-17 62.2 0.3 1e-16 61.0 0.3 1.5 1 0 0 1 1 1 1 START domain PH PF00169.29 CEG46335.1 - 8.5e-10 39.1 0.0 2.5e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG46335.1 - 0.0077 16.5 4.2 0.12 12.7 0.0 3.1 4 0 0 4 4 4 1 Pleckstrin homology domain PH_11 PF15413.6 CEG46335.1 - 0.053 13.9 2.6 0.21 12.0 1.0 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain TCR PF03638.15 CEG46336.1 - 1e-24 86.5 53.3 4e-12 46.2 21.5 2.6 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 CEG46336.1 - 2.9e-06 27.0 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEG46336.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 CEG46340.1 - 0.00058 20.6 0.1 1.7 9.6 0.0 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.11 CEG46340.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CEG46340.1 - 0.03 12.4 0.0 0.042 11.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family tRNA_U5-meth_tr PF05958.11 CEG46341.1 - 5.6e-19 68.3 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 CEG46341.1 - 7.1e-06 25.7 0.1 0.0038 16.8 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 CEG46341.1 - 1e-05 25.4 0.0 2.8e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG46341.1 - 0.00028 21.5 0.0 0.00085 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG46341.1 - 0.00041 19.8 0.1 0.00094 18.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CEG46341.1 - 0.0016 18.5 0.1 0.0016 18.5 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEG46341.1 - 0.0034 16.9 0.2 0.0081 15.6 0.2 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 CEG46341.1 - 0.018 14.4 0.7 0.066 12.5 0.1 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CEG46341.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.22 CEG46341.1 - 0.061 13.1 0.0 0.27 11.1 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AviRa PF11599.8 CEG46341.1 - 0.77 9.2 3.4 0.4 10.1 0.1 2.2 2 1 0 2 2 2 0 RRNA methyltransferase AviRa CSRNP_N PF16019.5 CEG46343.1 - 2 8.3 4.2 0.62 9.9 0.5 2.2 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF1869 PF08956.10 CEG46343.1 - 4 7.4 5.2 4.6 7.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) tRNA_anti-codon PF01336.25 CEG46344.1 - 0.00026 20.9 0.2 0.0013 18.6 0.2 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_REV PF03978.13 CEG46344.1 - 0.027 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Ribosom_S12_S23 PF00164.25 CEG46344.1 - 0.061 12.9 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S12/S23 Ribosomal_S17e PF00833.18 CEG46345.1 - 1.3e-58 196.2 0.2 1.5e-58 196.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 EF-hand_7 PF13499.6 CEG46346.1 - 7.2e-27 93.7 11.9 2.1e-13 50.5 3.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG46346.1 - 1.1e-23 80.9 13.3 2.3e-07 29.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CEG46346.1 - 2.1e-19 67.7 8.7 1e-06 28.2 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG46346.1 - 1.9e-16 59.6 14.9 2.2e-08 33.8 2.7 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CEG46346.1 - 8.3e-12 45.3 1.8 4.6e-05 23.7 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG46346.1 - 1.6e-11 43.2 9.4 0.00046 19.5 1.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CEG46346.1 - 5.9e-08 32.6 4.8 0.0016 18.4 0.4 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CEG46346.1 - 0.00019 22.2 0.4 0.054 14.4 0.1 2.1 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CEG46346.1 - 0.0031 17.8 0.1 0.88 9.9 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 CEG46346.1 - 0.0034 17.3 3.6 0.96 9.3 0.4 2.5 2 1 0 2 2 2 2 SurA N-terminal domain TerB PF05099.13 CEG46346.1 - 0.0046 16.9 4.2 2.3 8.2 0.2 3.0 2 1 1 3 3 3 2 Tellurite resistance protein TerB Unstab_antitox PF09720.10 CEG46346.1 - 0.021 14.9 0.2 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Putative addiction module component Dockerin_1 PF00404.18 CEG46346.1 - 0.025 14.8 3.1 1.9 8.7 0.1 2.6 1 1 1 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 CEG46346.1 - 0.031 14.2 1.3 13 5.7 0.0 3.1 1 1 3 4 4 4 0 Caleosin related protein CdiI PF07262.11 CEG46346.1 - 0.051 13.3 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 CDI immunity protein EF-hand_14 PF17959.1 CEG46346.1 - 0.089 13.2 1.1 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 EF-hand domain XS PF03468.14 CEG46346.1 - 0.1 12.9 0.3 0.35 11.2 0.1 1.8 2 0 0 2 2 2 0 XS domain DUF1636 PF07845.11 CEG46346.1 - 0.2 12.1 0.1 12 6.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1636) ORC3_N PF07034.11 CEG46347.1 - 9.7e-14 51.2 11.3 2.7e-12 46.5 7.2 3.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CEG46347.1 - 3.3e-08 33.7 0.5 3.3e-08 33.7 0.5 2.7 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal RNA_pol_N PF01194.17 CEG46348.1 - 5.9e-31 106.6 1.2 6.7e-31 106.4 1.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CEG46348.1 - 0.013 15.8 0.6 0.018 15.3 0.6 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) MmgE_PrpD PF03972.14 CEG46348.1 - 0.19 10.2 0.0 0.19 10.2 0.0 1.0 1 0 0 1 1 1 0 MmgE/PrpD family Raf1_HTH PF18579.1 CEG46352.1 - 0.019 14.7 0.1 13 5.6 0.0 3.4 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain RE_SinI PF09570.10 CEG46352.1 - 0.026 13.8 0.1 2.5 7.3 0.0 3.1 2 1 0 3 3 3 0 SinI restriction endonuclease HsbA PF12296.8 CEG46353.1 - 0.15 12.5 1.9 0.58 10.6 0.4 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A TGBp3 PF02495.17 CEG46353.1 - 4.2 7.1 5.8 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 Triple gene block 3 Glyco_hydro_31 PF01055.26 CEG46354.1 - 1.1e-134 450.0 3.2 1.4e-134 449.6 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEG46354.1 - 3.3e-21 75.4 0.5 6.3e-20 71.3 0.0 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like NIP_1 PF08995.10 CEG46355.1 - 0.051 14.0 0.3 0.051 14.0 0.3 2.7 2 0 0 2 2 2 0 Necrosis inducing protein-1 Ras PF00071.22 CEG46356.1 - 1.9e-53 180.4 0.0 2.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG46356.1 - 4.2e-32 110.9 0.0 6.8e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG46356.1 - 3.8e-11 42.8 0.0 5.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG46356.1 - 0.00029 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEG46356.1 - 0.00037 20.0 0.0 0.0015 18.0 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEG46356.1 - 0.016 14.8 0.3 0.026 14.1 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG46356.1 - 0.038 14.1 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CEG46356.1 - 0.11 12.5 0.1 0.4 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Lipase_3 PF01764.25 CEG46357.1 - 1.8e-23 82.9 0.3 8.3e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 CEG46357.1 - 0.0031 16.8 0.3 0.0086 15.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 CEG46357.1 - 0.013 15.0 0.1 0.068 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF4407 PF14362.6 CEG46357.1 - 0.12 11.7 19.7 0.041 13.2 8.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EnY2 PF10163.9 CEG46357.1 - 0.34 11.3 4.2 0.32 11.4 0.3 2.9 2 1 0 2 2 2 0 Transcription factor e(y)2 Mannitol_dh PF01232.23 CEG46357.1 - 0.51 10.5 2.9 1.3 9.2 2.9 1.7 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Exonuc_VII_L PF02601.15 CEG46357.1 - 1.2 8.6 13.8 1.8 8.0 0.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit mCpol PF18182.1 CEG46357.1 - 1.5 9.1 5.2 6.2 7.2 0.2 3.2 2 1 0 2 2 2 0 minimal CRISPR polymerase domain Baculo_PEP_C PF04513.12 CEG46357.1 - 3 7.9 12.6 1.7 8.7 3.3 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1451 PF07295.11 CEG46357.1 - 4.2 7.4 7.8 0.28 11.2 0.6 2.5 3 1 0 3 3 3 0 Zinc-ribbon containing domain DUF1140 PF06600.11 CEG46357.1 - 6.5 7.3 7.1 1.6 9.2 0.6 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1140) VPS13_C PF16909.5 CEG46358.1 - 4.6e-49 166.6 1.8 1e-45 155.7 0.1 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CEG46358.1 - 2.2e-23 83.3 8.7 5.9e-16 59.0 2.6 4.8 5 0 0 5 5 5 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 CEG46358.1 - 1.3e-22 80.4 1.9 5.7e-20 71.8 0.0 3.7 4 0 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 CEG46358.1 - 4.7e-22 78.7 0.3 2.6e-20 72.9 0.0 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 PX PF00787.24 CEG46358.1 - 2.7e-09 37.0 0.0 7.1e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PX domain ATG_C PF09333.11 CEG46358.1 - 0.00016 22.0 0.0 0.0006 20.1 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain bPH_1 PF08000.11 CEG46361.1 - 1.6e-22 79.8 0.4 2.3e-22 79.4 0.4 1.2 1 0 0 1 1 1 1 Bacterial PH domain WAK PF08488.11 CEG46361.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.7 1 1 1 2 2 2 0 Wall-associated kinase Macro PF01661.21 CEG46362.1 - 9.3e-17 61.2 0.0 1.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain Tim54 PF11711.8 CEG46362.1 - 0.12 11.2 0.2 0.16 10.7 0.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 CEG46362.1 - 0.46 8.7 7.2 0.67 8.2 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CEG46362.1 - 0.48 9.8 15.0 0.63 9.4 15.0 1.1 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.9 CEG46362.1 - 1.2 8.0 9.1 1.9 7.4 9.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.12 CEG46362.1 - 1.7 6.7 15.5 2.3 6.4 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 CEG46362.1 - 2.5 6.1 5.4 3.4 5.7 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 CEG46362.1 - 3 7.1 15.0 4.1 6.6 15.0 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 CEG46362.1 - 3.1 6.2 9.4 4.4 5.7 9.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 CEG46362.1 - 4.1 7.1 8.8 7.9 6.2 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CwfJ_C_1 PF04677.15 CEG46364.1 - 1.2e-28 99.4 0.6 2.4e-28 98.4 0.6 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CEG46364.1 - 0.00049 20.9 2.5 0.00098 20.0 0.0 2.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Orthopox_F7 PF05813.12 CEG46364.1 - 0.13 12.4 0.7 0.5 10.5 0.7 2.0 1 0 0 1 1 1 0 Orthopoxvirus F7 protein DUF4710 PF15828.5 CEG46364.1 - 4.8 7.4 13.8 1.1e+02 3.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) DUF4554 PF15091.6 CEG46366.1 - 0.062 12.2 0.6 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Kinetochor_Ybp2 PF08568.10 CEG46367.1 - 1.5e-09 36.9 0.3 3.9e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Fis1_TPR_N PF14852.6 CEG46367.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat DUF4148 PF13663.6 CEG46372.1 - 0.079 13.1 1.3 0.12 12.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PRIMA1 PF16101.5 CEG46373.1 - 0.85 9.7 2.4 1.7 8.7 0.3 2.1 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 RED_N PF07808.13 CEG46375.1 - 7.4e-22 78.1 7.2 7.6e-19 68.2 0.1 2.4 1 1 2 3 3 3 2 RED-like protein N-terminal region GDWWSH PF15667.5 CEG46375.1 - 0.0025 17.3 0.3 0.0055 16.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function with motif GDWWSH NAC PF01849.18 CEG46376.1 - 6.4e-21 74.1 0.0 1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 NAC domain Ribosomal_L23 PF00276.20 CEG46377.1 - 1.6e-21 76.4 3.1 1.9e-21 76.2 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 RasGAP PF00616.19 CEG46377.1 - 0.032 13.9 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase ubiquitin PF00240.23 CEG46377.1 - 0.089 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family Med18 PF09637.10 CEG46378.1 - 0.00042 20.2 0.0 0.039 13.8 0.0 2.9 1 1 0 1 1 1 1 Med18 protein Arm-DNA-bind_3 PF13356.6 CEG46379.1 - 0.75 10.2 4.1 2.5 8.6 4.1 2.1 1 1 0 1 1 1 0 Arm DNA-binding domain Glycos_transf_1 PF00534.20 CEG46380.1 - 4.9e-08 32.7 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG46380.1 - 5.2e-08 33.4 0.0 4.3e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEG46380.1 - 4.9e-07 30.3 0.2 8.2e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CEG46380.1 - 1.5e-06 28.3 0.1 2.6e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CEG46380.1 - 0.00026 21.3 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATPase_gene1 PF09527.10 CEG46382.1 - 3.6e-11 43.1 24.8 0.0087 16.2 2.0 5.5 3 2 1 5 5 5 5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter OMP_b-brl PF13505.6 CEG46382.1 - 3.1e-06 27.4 19.0 0.00082 19.5 12.4 2.9 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain Motilin_assoc PF04643.12 CEG46382.1 - 0.005 16.7 0.5 60 3.6 0.0 5.1 3 2 2 5 5 5 0 Motilin/ghrelin-associated peptide GT87 PF09594.10 CEG46382.1 - 0.024 14.4 19.4 33 4.1 0.1 6.5 7 0 0 7 7 7 0 Glycosyltransferase family 87 End_tail_spike PF12219.8 CEG46382.1 - 0.038 14.0 0.0 96 3.0 0.0 3.5 3 1 2 5 5 5 0 Catalytic domain of bacteriophage endosialidase NfrA_C PF13283.6 CEG46382.1 - 0.047 13.2 19.2 12 5.3 0.2 6.4 1 1 6 7 7 7 0 Bacteriophage N adsorption protein A C-term MspA PF09203.11 CEG46382.1 - 0.051 13.4 11.2 96 2.8 11.2 2.7 1 1 0 1 1 1 0 MspA Ion_trans PF00520.31 CEG46383.1 - 7.1e-23 81.1 10.1 9.1e-23 80.7 10.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEG46383.1 - 1.3e-11 44.3 6.3 1.3e-11 44.3 6.3 2.2 2 0 0 2 2 2 1 Ion channel Flavi_NS4A PF01350.17 CEG46383.1 - 0.024 14.6 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Metallophos PF00149.28 CEG46385.1 - 1.7e-32 113.6 0.0 2.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEG46385.1 - 4.7e-14 52.6 0.1 1e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TPR_12 PF13424.6 CEG46386.1 - 1.9e-09 37.7 21.5 0.00023 21.4 0.2 6.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEG46386.1 - 2e-07 30.7 10.5 0.038 13.9 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG46386.1 - 0.00053 19.8 13.0 0.48 10.6 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG46386.1 - 0.0018 18.0 17.7 0.6 10.0 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG46386.1 - 0.017 15.2 27.8 0.14 12.3 0.1 8.9 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF1870 PF08965.10 CEG46386.1 - 0.032 14.2 0.3 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) TPR_17 PF13431.6 CEG46386.1 - 0.037 14.4 2.0 47 4.7 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG46386.1 - 0.2 12.0 7.0 25 5.4 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 CEG46386.1 - 0.29 11.9 2.4 12 6.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG46386.1 - 0.36 11.5 12.3 1.2 9.8 0.3 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF4201 PF13870.6 CEG46387.1 - 3.1e-37 128.0 29.0 3.1e-37 128.0 29.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 CEG46387.1 - 0.23 11.9 28.9 0.18 12.2 1.0 5.6 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) NUP214 PF16755.5 CEG46387.1 - 1.8 7.7 8.7 0.057 12.7 0.9 2.0 1 1 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 NUDIX PF00293.28 CEG46388.1 - 1.5e-14 54.2 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 CEG46388.1 - 5.6e-08 32.9 1.4 5.6e-08 32.9 1.4 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding NUDIX_2 PF13869.6 CEG46388.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase OSK PF17182.4 CEG46388.1 - 0.078 12.2 0.4 0.24 10.6 0.0 1.9 2 1 0 2 2 2 0 OSK domain Orthopox_F7 PF05813.12 CEG46388.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus F7 protein zf-H2C2_2 PF13465.6 CEG46388.1 - 0.38 11.3 7.7 5.7 7.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain EF-hand_1 PF00036.32 CEG46389.1 - 1.9e-20 70.8 12.1 1.6e-06 27.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG46389.1 - 4.6e-16 59.0 9.9 1e-09 38.7 1.4 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG46389.1 - 1.1e-15 56.1 11.0 0.00014 21.5 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEG46389.1 - 2.3e-13 49.7 7.9 0.0011 18.7 0.1 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG46389.1 - 4.6e-12 44.9 10.3 7.6e-05 22.0 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CEG46389.1 - 0.0019 18.1 2.8 0.79 9.7 0.1 3.5 2 2 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG46389.1 - 0.025 14.9 0.2 2.6 8.4 0.3 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CEG46389.1 - 0.17 11.8 2.1 11 6.0 0.0 3.2 3 0 0 3 3 3 0 EF hand Ribosomal_L21e PF01157.18 CEG46390.1 - 0.0028 17.5 0.4 0.37 10.7 0.0 3.0 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_4 PF06347.13 CEG46390.1 - 0.17 11.7 0.4 5 7.0 0.1 2.9 2 1 1 3 3 3 0 Bacterial SH3 domain TB PF00683.17 CEG46390.1 - 1.8 8.4 5.3 4.5 7.1 5.3 1.6 1 1 0 1 1 1 0 TB domain Ras PF00071.22 CEG46391.1 - 3.9e-58 195.6 0.3 5e-58 195.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG46391.1 - 1.1e-36 125.7 0.2 1.5e-36 125.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG46391.1 - 1.3e-13 50.7 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEG46391.1 - 3.3e-05 23.5 0.2 0.00012 21.7 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEG46391.1 - 4.8e-05 22.8 0.3 7.9e-05 22.1 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG46391.1 - 8.8e-05 22.5 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEG46391.1 - 9.7e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEG46391.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 CEG46391.1 - 0.0063 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CEG46391.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain Acyltransferase PF01553.21 CEG46392.1 - 2.9e-14 52.8 0.0 6.3e-13 48.5 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase PLATZ PF04640.14 CEG46393.1 - 0.094 13.3 2.9 0.11 13.1 0.9 1.9 2 0 0 2 2 2 0 PLATZ transcription factor ACC_central PF08326.12 CEG46394.1 - 2.1e-179 598.2 11.1 2.6e-179 597.9 11.1 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CEG46394.1 - 4.1e-152 507.3 0.0 6.1e-152 506.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CEG46394.1 - 4.5e-46 157.0 0.0 1.2e-45 155.6 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEG46394.1 - 2.3e-26 92.5 0.0 5.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEG46394.1 - 8.4e-23 80.5 0.0 2.4e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEG46394.1 - 2.2e-08 33.8 0.0 5.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CEG46394.1 - 0.0014 18.2 0.0 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEG46394.1 - 0.002 18.2 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 CEG46394.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 CEG46394.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus BRE1 PF08647.11 CEG46394.1 - 0.18 11.9 0.7 0.57 10.3 0.7 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase RFC1 PF08519.12 CEG46395.1 - 1e-38 133.0 0.2 3.6e-38 131.2 0.1 2.1 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CEG46395.1 - 1.5e-13 51.3 1.6 4.3e-13 49.8 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CEG46395.1 - 3.7e-10 40.0 0.0 1.3e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CEG46395.1 - 6.1e-07 29.5 0.3 3.4e-06 27.1 0.3 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CEG46395.1 - 4.6e-06 26.5 0.0 1.2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CEG46395.1 - 0.0002 21.1 0.9 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEG46395.1 - 0.00028 21.2 0.1 0.002 18.4 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.6 CEG46395.1 - 0.00057 20.3 0.4 0.0029 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 CEG46395.1 - 0.00073 19.5 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 CEG46395.1 - 0.00092 19.4 1.0 0.036 14.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CEG46395.1 - 0.0013 19.2 0.0 0.0048 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEG46395.1 - 0.0015 18.6 0.2 0.0067 16.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEG46395.1 - 0.0028 17.2 0.1 0.0065 16.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CEG46395.1 - 0.004 17.1 0.1 0.023 14.6 0.1 2.2 2 1 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CEG46395.1 - 0.0097 16.3 0.2 0.16 12.4 0.0 2.9 2 1 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 CEG46395.1 - 0.017 14.3 0.1 0.064 12.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 CEG46395.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 CEG46395.1 - 0.023 15.0 0.0 0.086 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CEG46395.1 - 0.025 15.0 0.2 0.23 11.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CEG46395.1 - 0.029 14.4 0.7 0.12 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG46395.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CEG46395.1 - 0.1 12.9 1.6 2.9 8.2 0.3 3.0 2 1 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.7 CEG46395.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain ABC_tran PF00005.27 CEG46395.1 - 0.23 12.0 7.1 0.91 10.0 0.0 3.2 3 1 0 3 3 3 0 ABC transporter Nuc_sug_transp PF04142.15 CEG46396.1 - 5.1e-107 357.7 17.2 5.8e-107 357.5 17.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CEG46396.1 - 3.5e-09 36.3 15.0 4.3e-09 36.0 15.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEG46396.1 - 1.9e-05 24.9 25.0 0.00049 20.3 3.8 2.7 2 2 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CEG46396.1 - 0.034 13.4 17.8 0.073 12.3 17.7 1.5 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Mon1 PF03164.14 CEG46396.1 - 0.055 12.5 0.4 0.082 12.0 0.4 1.3 1 0 0 1 1 1 0 Trafficking protein Mon1 PMT_4TMC PF16192.5 CEG46396.1 - 1.2 8.7 6.3 0.52 9.9 3.0 1.9 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Trp_oprn_chp PF09534.10 CEG46396.1 - 1.9 8.2 5.0 2.4 7.9 0.3 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM234 PF10639.9 CEG46396.1 - 5.5 7.0 9.3 5.1 7.2 1.1 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF4604 PF15377.6 CEG46397.1 - 1.9 8.9 10.4 0.97 9.8 7.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) XRN_N PF03159.18 CEG46399.1 - 4.5e-87 291.5 0.0 7.4e-87 290.8 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CEG46399.1 - 3.7e-84 283.2 0.0 6.5e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN1_D1 PF18332.1 CEG46399.1 - 7.4e-20 71.5 0.0 1.6e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CEG46399.1 - 1.5e-16 60.2 0.1 3.1e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 CEG46399.1 - 0.0015 18.7 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain CCDC23 PF15674.5 CEG46400.1 - 0.00033 20.6 12.9 0.0042 17.0 12.9 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 23 DUF1682 PF07946.14 CEG46400.1 - 0.0094 15.2 7.6 0.011 14.9 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Taq-exonuc PF09281.10 CEG46400.1 - 0.11 12.4 2.4 0.22 11.5 2.4 1.4 1 0 0 1 1 1 0 Taq polymerase, exonuclease FAM199X PF15814.5 CEG46400.1 - 0.14 11.2 2.8 0.17 10.9 2.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X MCU PF04678.13 CEG46400.1 - 0.15 12.2 1.6 0.18 11.9 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ank_4 PF13637.6 CEG46401.1 - 5.4e-17 61.9 6.4 4.3e-07 30.4 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG46401.1 - 3.2e-15 56.5 3.7 2e-06 28.3 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG46401.1 - 4.6e-14 52.3 9.3 3.7e-05 23.9 0.2 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG46401.1 - 2.3e-06 27.5 4.3 5.5 7.9 0.0 6.3 3 1 3 6 6 6 2 Ankyrin repeat Ank PF00023.30 CEG46401.1 - 0.0048 17.3 0.5 10 6.8 0.0 4.3 2 1 2 4 4 4 2 Ankyrin repeat Gp_dh_N PF00044.24 CEG46403.1 - 3e-21 75.7 0.0 4.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 CEG46403.1 - 4.1e-07 29.7 0.0 4.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain RVT_1 PF00078.27 CEG46404.1 - 2.7e-19 69.6 0.1 7.6e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HpuA PF16960.5 CEG46404.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter HA PF03457.14 CEG46405.1 - 0.0039 17.5 0.1 0.0039 17.5 0.1 1.1 1 0 0 1 1 1 1 Helicase associated domain PI3_PI4_kinase PF00454.27 CEG46406.1 - 4.2e-33 115.2 0.1 9.9e-31 107.4 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 CEG46406.1 - 3.3e-07 30.4 14.4 3.3e-07 30.4 14.4 2.1 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.21 CEG46406.1 - 1.9e-05 24.7 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4135 PF13575.6 CEG46406.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) ACT PF01842.25 CEG46408.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 ACT domain MIT PF04212.18 CEG46409.1 - 0.0022 18.0 0.3 0.0022 18.0 0.3 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.14 CEG46414.1 - 1.6e-33 116.2 2.6 1.5e-26 93.5 0.1 3.6 3 1 0 4 4 4 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEG46414.1 - 6.7e-14 52.4 0.0 9.8e-06 26.0 0.0 3.3 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG46414.1 - 2.3e-06 27.6 0.3 0.0012 18.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEG46414.1 - 2.4e-05 23.8 1.3 0.0044 16.4 0.7 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 CEG46414.1 - 6.8e-05 22.1 0.3 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 CEG46414.1 - 9.7e-05 22.1 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CEG46414.1 - 0.00011 22.6 0.3 0.00053 20.4 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain ClpB_D2-small PF10431.9 CEG46414.1 - 0.00015 21.8 0.1 0.00059 19.8 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein T2SSE PF00437.20 CEG46414.1 - 0.0002 20.5 0.2 0.001 18.2 0.0 2.0 1 1 1 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.12 CEG46414.1 - 0.00039 20.2 1.0 0.45 10.2 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain G-alpha PF00503.20 CEG46414.1 - 0.00075 18.7 0.3 0.0013 18.0 0.3 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.6 CEG46414.1 - 0.0011 19.5 0.3 0.0046 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CEG46414.1 - 0.0012 18.2 0.0 0.003 16.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.29 CEG46414.1 - 0.0017 18.2 0.8 0.012 15.4 0.8 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase TIP49 PF06068.13 CEG46414.1 - 0.0018 17.6 0.1 0.0041 16.4 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain CPT PF07931.12 CEG46414.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 CEG46414.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEG46414.1 - 0.0097 15.9 0.2 1 9.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain Torsin PF06309.11 CEG46414.1 - 0.012 15.8 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.6 CEG46414.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG46414.1 - 0.015 15.6 0.8 0.098 12.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CEG46414.1 - 0.018 14.8 0.9 0.082 12.6 0.3 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 CEG46414.1 - 0.019 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CEG46414.1 - 0.038 13.9 1.5 0.43 10.5 0.0 2.3 1 1 0 2 2 2 0 Rad17 P-loop domain FGGY_C PF02782.16 CEG46414.1 - 0.06 13.1 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain IPT PF01745.16 CEG46414.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase AAA_17 PF13207.6 CEG46414.1 - 1.4 9.4 4.5 4.8 7.6 0.2 3.4 3 1 1 4 4 4 0 AAA domain KfrA_N PF11740.8 CEG46414.1 - 1.5 9.5 6.2 89 3.8 0.1 3.8 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term AAA_19 PF13245.6 CEG46414.1 - 2.8 8.3 9.3 4.7 7.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain DnaJ PF00226.31 CEG46417.1 - 4e-25 87.7 0.8 4e-25 87.7 0.8 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 CEG46417.1 - 6.2e-22 77.9 0.2 1.4e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 CEG46417.1 - 4.9e-05 23.1 0.1 0.0004 20.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG46417.1 - 0.0031 17.3 0.3 0.016 15.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG46417.1 - 0.042 13.9 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEG46417.1 - 0.043 14.1 0.1 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 CEG46417.1 - 0.051 13.0 0.5 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like PRAI PF00697.22 CEG46417.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SRAP PF02586.14 CEG46418.1 - 1.9e-64 217.2 0.0 2.5e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) MRP_L53 PF10780.9 CEG46419.1 - 0.0075 16.4 0.5 0.014 15.6 0.1 1.7 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 RNase_P_Rpp14 PF01900.19 CEG46420.1 - 1.2e-24 86.5 1.5 1.5e-24 86.2 1.5 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Tfb2 PF03849.14 CEG46420.1 - 0.046 12.7 0.1 0.054 12.4 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 PLA2_inh PF02988.15 CEG46420.1 - 0.076 13.7 0.3 0.13 12.9 0.3 1.5 1 0 0 1 1 1 0 Phospholipase A2 inhibitor EXOSC1 PF10447.9 CEG46421.1 - 1.6e-09 38.4 4.5 4.4e-05 24.1 0.0 2.8 1 1 2 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CEG46421.1 - 2e-07 30.7 0.0 4.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region TPR_1 PF00515.28 CEG46422.1 - 4.3e-18 64.3 2.7 1e-07 31.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG46422.1 - 2.6e-17 61.5 3.0 8.6e-08 31.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG46422.1 - 9.2e-13 47.7 0.3 5.3e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 CEG46422.1 - 1.7e-08 34.0 0.2 0.0021 18.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG46422.1 - 8.5e-08 32.2 1.2 8.5e-08 32.2 1.2 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG46422.1 - 1.9e-06 28.4 4.0 8.9e-06 26.3 3.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG46422.1 - 3.7e-06 26.9 0.7 0.019 15.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG46422.1 - 2.4e-05 24.5 3.6 0.0017 18.6 1.2 3.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG46422.1 - 0.0022 17.9 2.8 0.62 10.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG46422.1 - 0.0036 17.3 0.2 0.027 14.5 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CEG46422.1 - 0.0088 16.8 10.6 0.022 15.6 0.1 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG46422.1 - 0.013 16.0 3.3 0.59 10.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG46422.1 - 3.8 7.5 14.5 0.63 10.0 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 CEG46423.1 - 3.4e-26 91.0 10.4 6.9e-05 23.5 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46423.1 - 4.7e-09 36.4 0.0 0.037 14.3 0.0 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG46423.1 - 1.9e-05 23.8 1.4 0.1 11.5 0.0 4.0 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEG46423.1 - 0.00031 20.7 0.0 0.041 13.7 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEG46423.1 - 0.038 12.6 0.2 1.3 7.6 0.2 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PNP_UDP_1 PF01048.20 CEG46424.1 - 8.9e-46 156.0 0.0 1.1e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Snf7 PF03357.21 CEG46425.1 - 4.8e-14 52.3 11.8 6.8e-14 51.8 11.8 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CEG46425.1 - 0.0014 18.6 1.3 0.0018 18.2 1.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TetR_C_2 PF08361.11 CEG46425.1 - 0.027 14.6 1.2 0.048 13.8 1.2 1.4 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Cytochrom_B562 PF07361.11 CEG46425.1 - 1.1 10.0 11.7 1.3 9.7 3.5 2.9 2 2 0 2 2 2 0 Cytochrome b562 EXS PF03124.14 CEG46426.1 - 2e-80 270.6 25.0 3.1e-80 270.0 25.0 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CEG46426.1 - 2.5e-19 70.5 8.2 3.6e-10 40.3 0.6 3.1 1 1 2 3 3 3 3 SPX domain TCTP PF00838.17 CEG46427.1 - 1.8e-43 148.7 3.7 2.1e-43 148.6 3.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CelTOS PF18659.1 CEG46427.1 - 0.042 14.3 0.1 0.12 12.8 0.0 1.7 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DUF2232 PF09991.9 CEG46427.1 - 0.13 11.4 0.1 0.18 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3591 PF12157.8 CEG46428.1 - 4.3e-101 338.7 2.1 9.6e-64 215.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CEG46428.1 - 5.5e-19 68.0 0.2 1.1e-18 67.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 CEG46428.1 - 7.8e-05 22.4 0.2 0.00022 21.0 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle HypA PF01155.19 CEG46428.1 - 0.19 11.7 1.4 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RILP PF11461.8 CEG46430.1 - 0.056 13.7 0.5 0.22 11.8 0.5 2.0 1 0 0 1 1 1 0 Rab interacting lysosomal protein HA PF03457.14 CEG46432.1 - 1.4e-17 63.7 2.8 0.0024 18.2 0.0 6.8 6 0 0 6 6 6 6 Helicase associated domain Beta-lactamase PF00144.24 CEG46433.1 - 1.2e-22 80.7 0.0 1.6e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase UPF0489 PF12640.7 CEG46435.1 - 1.5e-35 123.0 0.3 2.7e-35 122.2 0.3 1.4 1 0 0 1 1 1 1 UPF0489 domain ATP12 PF07542.11 CEG46435.1 - 0.076 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 ATP12 chaperone protein DUF775 PF05603.12 CEG46438.1 - 1.5e-37 129.1 0.1 6.2e-36 123.8 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Tyrosinase PF00264.20 CEG46439.1 - 3.2e-22 79.9 0.4 3.2e-22 79.9 0.4 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Syja_N PF02383.18 CEG46441.1 - 3.3e-77 259.9 0.5 4.3e-77 259.6 0.5 1.1 1 0 0 1 1 1 1 SacI homology domain DnaJ PF00226.31 CEG46442.1 - 4.5e-24 84.4 1.1 4.5e-24 84.4 1.1 1.9 2 0 0 2 2 2 1 DnaJ domain Tmemb_185A PF10269.9 CEG46442.1 - 7.3e-13 48.8 12.1 7.3e-13 48.8 12.1 2.8 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein GWT1 PF06423.12 CEG46442.1 - 0.0098 16.0 1.8 0.21 11.7 0.0 2.5 2 0 0 2 2 2 1 GWT1 ATP-synt_8 PF00895.20 CEG46442.1 - 0.076 13.5 0.0 0.076 13.5 0.0 3.8 4 0 0 4 4 4 0 ATP synthase protein 8 DUF493 PF04359.14 CEG46442.1 - 0.12 13.0 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF493) CrgA PF06781.12 CEG46442.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.0 4 0 0 4 4 4 0 Cell division protein CrgA DPM3 PF08285.11 CEG46442.1 - 0.52 10.5 12.5 0.77 10.0 0.7 3.7 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Flavin_Reduct PF01613.18 CEG46443.1 - 5.7e-07 29.7 0.3 3.1e-06 27.3 0.3 1.8 1 1 0 1 1 1 1 Flavin reductase like domain Tyrosinase PF00264.20 CEG46444.1 - 3.6e-20 73.2 1.2 3.2e-19 70.1 1.2 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 CEG46445.1 - 1.6e-17 64.6 0.3 7.8e-17 62.3 0.3 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF5363 PF17320.2 CEG46445.1 - 0.044 13.6 0.3 0.096 12.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5363) zf-H2C2_5 PF13909.6 CEG46449.1 - 0.17 11.7 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain PH PF00169.29 CEG46450.1 - 1.8e-07 31.6 0.1 3.2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG46450.1 - 0.0012 19.1 0.1 0.0022 18.2 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CEG46450.1 - 0.0016 18.8 3.1 0.041 14.3 3.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Peptidase_M3 PF01432.20 CEG46451.1 - 8.1e-126 420.9 0.0 1e-125 420.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CEG46451.1 - 0.19 11.3 1.0 0.33 10.6 1.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like FG-GAP PF01839.23 CEG46452.1 - 0.001 19.1 0.5 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 FG-GAP repeat BBS2_Mid PF14783.6 CEG46452.1 - 0.0048 16.9 0.7 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 CEG46452.1 - 0.0067 15.5 1.7 0.44 9.5 0.3 3.5 4 0 0 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CEG46452.1 - 0.012 16.1 3.3 1.6 9.4 0.0 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HSF_DNA-bind PF00447.17 CEG46453.1 - 2.3e-31 108.3 3.2 3.6e-31 107.6 3.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding FliT PF05400.13 CEG46453.1 - 0.054 14.3 0.1 0.12 13.2 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT GAT PF03127.14 CEG46453.1 - 0.24 11.7 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 GAT domain CLIP_SPH_Scar PF18399.1 CEG46456.1 - 0.06 13.5 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface TIG PF01833.24 CEG46461.1 - 1.1e-64 214.5 51.1 5e-10 39.3 2.0 12.4 12 0 0 12 12 12 11 IPT/TIG domain Anth_Ig PF05587.13 CEG46461.1 - 8.5e-12 45.3 4.4 0.012 15.9 0.0 7.0 8 0 0 8 8 8 4 Anthrax receptor extracellular domain TIG_plexin PF17960.1 CEG46461.1 - 6.1e-08 32.6 5.4 5.6 7.0 0.0 8.4 10 0 0 10 10 10 2 TIG domain Laminin_G_3 PF13385.6 CEG46461.1 - 7.9e-06 26.1 0.1 1.8e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TIG PF01833.24 CEG46462.1 - 9.1e-244 788.4 204.0 3.6e-11 43.0 0.0 45.5 45 1 0 45 45 45 40 IPT/TIG domain TIG_plexin PF17960.1 CEG46462.1 - 1.4e-40 137.2 27.8 0.49 10.4 0.0 30.3 34 0 0 34 34 34 11 TIG domain Neocarzinostat PF00960.18 CEG46462.1 - 2.3 8.3 6.1 10 6.1 0.0 4.3 3 0 0 3 3 3 0 Neocarzinostatin family WD40 PF00400.32 CEG46463.1 - 1.2e-10 41.7 6.0 1.6e-05 25.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46463.1 - 1.7e-05 25.0 1.3 0.045 14.0 0.1 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 CEG46464.1 - 0.00036 20.7 1.7 0.051 13.8 0.2 2.2 1 1 1 2 2 2 2 Homeobox associated leucine zipper Csm1_N PF18504.1 CEG46464.1 - 0.011 16.1 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain Cnn_1N PF07989.11 CEG46464.1 - 0.016 15.3 0.2 0.025 14.7 0.2 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Speriolin_N PF15058.6 CEG46464.1 - 0.021 15.0 0.1 0.021 15.0 0.1 1.1 1 0 0 1 1 1 0 Speriolin N terminus bZIP_1 PF00170.21 CEG46464.1 - 0.023 14.8 1.4 0.038 14.1 1.1 1.4 1 1 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 CEG46464.1 - 0.031 14.7 0.2 0.038 14.4 0.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB SNO PF01174.19 CEG46465.1 - 3.7e-49 167.1 0.0 4.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CEG46465.1 - 2.1e-09 37.3 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 CEG46465.1 - 3.6e-06 26.8 0.1 4.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 CEG46465.1 - 0.0034 17.2 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 CEG46465.1 - 0.016 15.0 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEG46465.1 - 0.14 11.9 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase C26 HEAT PF02985.22 CEG46466.1 - 2.8e-25 86.2 31.2 0.0033 17.6 0.0 11.9 12 0 0 12 12 12 8 HEAT repeat HEAT_2 PF13646.6 CEG46466.1 - 1.5e-17 63.8 20.9 0.00013 22.3 0.4 6.6 4 2 2 6 6 6 6 HEAT repeats HEAT_EZ PF13513.6 CEG46466.1 - 1e-10 41.9 11.7 0.00061 20.2 0.1 7.3 7 1 0 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEG46466.1 - 8.9e-10 39.0 3.3 0.025 15.2 0.3 5.6 2 2 3 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CEG46466.1 - 0.0055 15.3 9.9 0.25 9.8 0.1 4.2 1 1 1 4 4 4 1 Adaptin N terminal region HrpJ PF07201.11 CEG46466.1 - 0.0069 16.7 0.4 1.3 9.3 0.0 2.8 3 0 0 3 3 3 1 HrpJ-like domain Ipi1_N PF12333.8 CEG46466.1 - 0.13 12.9 0.1 0.47 11.1 0.1 2.0 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation RasGEF_N_2 PF14663.6 CEG46466.1 - 0.39 11.1 3.6 19 5.7 0.1 4.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2009 PF09418.10 CEG46467.1 - 2.6e-202 672.9 0.0 3.1e-202 672.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CEG46467.1 - 0.00013 22.1 3.9 0.00026 21.1 3.9 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CEG46467.1 - 0.046 14.0 3.8 0.1 12.8 3.8 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Myb_DNA-binding PF00249.31 CEG46468.1 - 1.7e-06 28.1 0.1 3.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Neur_chan_memb PF02932.16 CEG46468.1 - 0.39 10.7 3.4 0.75 9.8 3.4 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_19 PF14559.6 CEG46469.1 - 4.8e-51 171.1 35.9 2.4e-07 31.2 0.9 16.5 12 3 4 16 16 16 12 Tetratricopeptide repeat TPR_14 PF13428.6 CEG46469.1 - 1.9e-35 118.5 32.6 0.013 16.3 0.0 19.4 14 5 7 21 21 20 8 Tetratricopeptide repeat TPR_2 PF07719.17 CEG46469.1 - 6.6e-35 116.4 40.4 0.018 15.1 0.0 20.2 23 0 0 23 23 20 7 Tetratricopeptide repeat TPR_8 PF13181.6 CEG46469.1 - 4.2e-23 79.6 33.4 0.04 14.1 0.0 17.2 20 0 0 20 20 17 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEG46469.1 - 1.1e-22 78.8 39.8 0.01 15.6 0.0 15.7 19 0 0 19 19 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEG46469.1 - 4.9e-21 75.1 26.0 0.015 16.0 0.9 13.0 11 3 4 15 15 14 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG46469.1 - 9.4e-21 73.8 27.3 0.00028 21.0 0.0 9.5 7 1 3 10 10 10 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CEG46469.1 - 6.9e-17 61.5 36.9 0.0013 19.0 0.2 14.0 11 3 1 13 13 13 5 Tetratricopeptide repeat TPR_9 PF13371.6 CEG46469.1 - 8.7e-15 54.6 24.8 5.6e-05 23.2 0.1 8.7 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEG46469.1 - 9.4e-13 47.2 22.5 0.029 14.4 0.0 13.4 13 1 1 14 14 13 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG46469.1 - 8.1e-11 41.5 21.3 13 6.4 0.1 14.4 16 0 0 16 16 13 0 Tetratricopeptide repeat NARP1 PF12569.8 CEG46469.1 - 2.7e-09 36.5 13.4 0.095 11.6 0.3 7.2 7 3 1 8 8 8 3 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 CEG46469.1 - 2.3e-08 33.6 19.7 0.021 14.5 0.0 9.3 11 0 0 11 11 8 3 TPR repeat TPR_6 PF13174.6 CEG46469.1 - 3.2e-08 33.7 35.1 0.68 10.7 0.2 15.4 20 0 0 20 20 14 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEG46469.1 - 1.8e-07 31.1 12.7 42 5.2 0.3 10.8 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEG46469.1 - 5.2e-05 23.0 17.3 0.38 10.4 0.5 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat-like domain RPN7 PF10602.9 CEG46469.1 - 0.00018 21.2 3.7 1 9.0 0.0 5.2 5 1 0 5 5 3 1 26S proteasome subunit RPN7 Coatomer_E PF04733.14 CEG46469.1 - 0.00049 19.6 9.4 1.4 8.2 0.0 5.1 6 0 0 6 6 6 2 Coatomer epsilon subunit HrpB1_HrpK PF09613.10 CEG46469.1 - 0.00056 19.6 5.7 0.15 11.7 0.0 6.3 6 1 1 7 7 6 1 Bacterial type III secretion protein (HrpB1_HrpK) YfiO PF13525.6 CEG46469.1 - 0.0018 18.0 7.1 0.78 9.4 0.0 5.8 5 2 1 6 6 6 1 Outer membrane lipoprotein ChAPs PF09295.10 CEG46469.1 - 0.0038 16.3 5.8 0.059 12.4 0.3 4.5 5 1 1 6 6 6 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4919 PF16266.5 CEG46469.1 - 0.0058 16.6 2.7 1.5 8.8 0.0 4.4 3 2 1 5 5 4 1 Domain of unknown function (DUF4919) SRP_TPR_like PF17004.5 CEG46469.1 - 0.01 15.9 5.2 46 4.1 0.0 5.9 6 0 0 6 6 5 0 Putative TPR-like repeat LppC PF04348.13 CEG46469.1 - 0.014 14.2 7.0 0.2 10.4 0.3 3.1 2 1 1 3 3 3 0 LppC putative lipoprotein PknG_TPR PF16918.5 CEG46469.1 - 0.019 13.7 4.9 0.31 9.7 0.0 4.3 4 1 0 4 4 4 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 CEG46469.1 - 0.021 15.1 20.5 0.57 10.5 0.2 7.9 9 1 1 10 10 8 0 Tetratricopeptide repeat Arabinose_bd PF12625.7 CEG46469.1 - 0.024 14.7 0.1 0.075 13.1 0.1 1.8 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term PPR PF01535.20 CEG46469.1 - 0.093 13.0 0.6 1.1e+02 3.4 0.0 5.6 6 0 0 6 6 2 0 PPR repeat Fis1_TPR_C PF14853.6 CEG46469.1 - 0.095 12.8 14.3 79 3.4 0.1 8.2 9 1 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CEG46469.1 - 0.24 11.5 6.6 7.2 6.7 0.2 5.3 6 1 0 6 6 4 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 CEG46469.1 - 0.24 11.8 9.6 24 5.4 0.0 6.1 6 1 1 7 7 5 0 Alkyl sulfatase dimerisation T6SS_VasJ PF16989.5 CEG46469.1 - 3.4 7.1 7.7 4.2 6.8 0.2 4.0 4 1 1 5 5 5 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ MIT PF04212.18 CEG46469.1 - 5.5 7.1 9.6 1.2e+02 2.8 0.1 6.2 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain zf-C2HC_2 PF13913.6 CEG46470.1 - 7.9e-15 54.3 14.9 2.1e-09 37.0 0.3 3.0 3 0 0 3 3 3 2 zinc-finger of a C2HC-type WW PF00397.26 CEG46470.1 - 3.2e-08 33.5 1.6 7.2e-08 32.4 1.6 1.6 1 0 0 1 1 1 1 WW domain MTP18 PF10558.9 CEG46470.1 - 0.095 12.6 0.8 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Jas PF16135.5 CEG46470.1 - 0.48 10.6 3.0 1.4 9.1 0.5 2.6 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf_UBZ PF18439.1 CEG46470.1 - 1.3 8.7 6.2 29 4.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF778 PF05608.12 CEG46471.1 - 1.5e-35 123.3 5.8 2.2e-19 70.6 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CEG46471.1 - 0.021 14.4 0.2 0.032 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) tRNA-synt_2d PF01409.20 CEG46474.1 - 1.9e-51 174.9 0.1 4e-51 173.9 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DENN PF02141.21 CEG46474.1 - 8.3e-26 91.1 1.6 2.2e-25 89.7 1.6 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain FDX-ACB PF03147.14 CEG46474.1 - 2.3e-21 76.0 0.0 7e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF4600 PF15372.6 CEG46474.1 - 0.024 15.1 2.6 0.056 13.9 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) uDENN PF03456.18 CEG46474.1 - 0.12 13.2 0.1 0.27 12.0 0.1 1.7 1 0 0 1 1 1 0 uDENN domain PNP_UDP_1 PF01048.20 CEG46475.1 - 6.9e-13 48.4 0.2 8.7e-13 48.1 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Anoctamin PF04547.12 CEG46477.1 - 1.6e-90 304.2 13.3 1.9e-90 303.9 13.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel CH PF00307.31 CEG46478.1 - 1.1e-41 141.4 0.1 8.7e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CDC24 PF06395.11 CEG46478.1 - 0.00013 22.2 0.4 0.15 12.3 0.1 2.3 2 0 0 2 2 2 2 CDC24 Calponin CAMSAP_CH PF11971.8 CEG46478.1 - 0.00028 20.7 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain DUF2017 PF09438.10 CEG46478.1 - 0.12 12.2 0.3 21 5.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2017) SIR2 PF02146.17 CEG46479.1 - 4.5e-48 163.5 0.0 5.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 CEG46479.1 - 0.075 13.2 0.4 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1754 PF08555.10 CEG46480.1 - 3.1e-05 24.7 4.0 3.1e-05 24.7 4.0 2.3 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Pkinase PF00069.25 CEG46482.1 - 1.5e-66 224.4 0.0 2e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46482.1 - 5.6e-35 120.9 0.0 7.6e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KHA PF11834.8 CEG46482.1 - 3.5e-09 36.6 0.0 7.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Kinase-like PF14531.6 CEG46482.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG46482.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 CEG46483.1 - 1.6e-46 157.4 0.0 1.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEG46483.1 - 0.0062 16.2 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEG46483.1 - 0.091 12.6 0.2 0.2 11.5 0.2 1.6 1 1 0 1 1 1 0 UEV domain THOC7 PF05615.13 CEG46484.1 - 3.3e-22 79.2 5.0 3.3e-22 79.2 5.0 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 FadA PF09403.10 CEG46484.1 - 0.00042 20.7 19.2 0.00059 20.3 2.8 3.1 2 1 1 3 3 3 2 Adhesion protein FadA ArgoMid PF16487.5 CEG46484.1 - 0.0049 17.1 0.5 0.025 14.8 0.2 2.1 1 1 0 2 2 2 1 Mid domain of argonaute BCDHK_Adom3 PF10436.9 CEG46484.1 - 0.068 13.0 0.7 0.093 12.6 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NPV_P10 PF05531.12 CEG46484.1 - 0.38 11.2 5.5 20 5.7 5.1 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 CEG46484.1 - 0.42 11.2 10.4 0.45 11.1 7.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Aida_N PF08910.10 CEG46484.1 - 0.66 10.4 8.3 2.9 8.3 1.3 2.9 2 1 1 3 3 3 0 Aida N-terminus ALMT PF11744.8 CEG46484.1 - 1.6 7.5 7.9 2.6 6.8 7.7 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter TMPIT PF07851.13 CEG46484.1 - 4.5 6.4 11.8 2.6 7.2 6.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein SlyX PF04102.12 CEG46484.1 - 5.9 7.6 8.1 14 6.4 4.8 2.5 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 CEG46484.1 - 6.1 6.9 10.3 7 6.7 1.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) R3H-assoc PF13902.6 CEG46484.1 - 8.6 6.8 8.6 5.7 7.3 1.1 2.4 2 1 0 2 2 2 0 R3H-associated N-terminal domain MutS_V PF00488.21 CEG46488.1 - 1.5e-62 211.0 0.0 4.3e-62 209.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEG46488.1 - 5.2e-30 105.1 0.5 1.8e-29 103.3 0.5 1.9 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CEG46488.1 - 6.7e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CEG46488.1 - 1.1e-07 32.2 0.1 3.6e-07 30.5 0.1 1.9 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 CEG46488.1 - 0.00031 20.4 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEG46488.1 - 0.019 14.7 0.1 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG46488.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tobravirus_2B PF05271.11 CEG46488.1 - 0.19 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Tobravirus 2B protein Polysacc_deac_1 PF01522.21 CEG46491.1 - 1.2e-10 41.4 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Atg14 PF10186.9 CEG46492.1 - 1.3e-07 31.0 12.7 5.5e-06 25.7 12.7 2.2 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 CEG46492.1 - 0.0013 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain C2 PF00168.30 CEG46492.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 C2 domain PI3_PI4_kinase PF00454.27 CEG46493.1 - 1.1e-19 71.3 0.0 2e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RXLR PF16810.5 CEG46496.1 - 0.081 13.4 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cellulose_synt PF03552.14 CEG46497.1 - 5.6e-22 78.1 1.7 2.3e-13 49.6 0.0 3.7 3 1 1 4 4 4 2 Cellulose synthase Glyco_trans_2_3 PF13632.6 CEG46497.1 - 3.9e-14 53.0 0.0 3.9e-14 53.0 0.0 2.9 4 0 0 4 4 4 1 Glycosyl transferase family group 2 PH PF00169.29 CEG46497.1 - 2.6e-09 37.5 0.1 5.6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Glyco_tranf_2_3 PF13641.6 CEG46497.1 - 2.2e-05 24.5 0.0 0.0058 16.6 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEG46497.1 - 0.00025 20.6 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 PH_8 PF15409.6 CEG46497.1 - 0.0004 20.6 0.4 0.004 17.4 0.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Glycos_transf_2 PF00535.26 CEG46497.1 - 0.0012 18.7 0.0 2.8 7.7 0.0 3.6 4 0 0 4 4 4 1 Glycosyl transferase family 2 Mcp5_PH PF12814.7 CEG46497.1 - 0.0035 17.4 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-C6H2 PF15801.5 CEG46497.1 - 0.0039 17.5 8.0 0.0039 17.5 8.0 2.4 3 0 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 CEG46497.1 - 0.011 16.1 0.4 0.065 13.7 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain TSP_1 PF00090.19 CEG46500.1 - 3.5e-47 158.4 317.8 6.1e-06 26.4 5.3 36.1 37 1 0 37 37 37 30 Thrombospondin type 1 domain PTN_MK_C PF01091.18 CEG46500.1 - 7e-19 68.0 199.9 0.012 16.0 0.7 33.0 25 7 9 34 34 34 20 PTN/MK heparin-binding protein family, C-terminal domain DUF4392 PF14336.6 CEG46500.1 - 1.7 8.0 5.2 28 4.0 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4392) MULE PF10551.9 CEG46503.1 - 1.3e-07 32.0 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 CEG46503.1 - 0.0069 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.18 CEG46503.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family AT_hook PF02178.19 CEG46503.1 - 0.6 10.2 5.3 1.2 9.3 5.3 1.5 1 0 0 1 1 1 0 AT hook motif Ank_4 PF13637.6 CEG46504.1 - 4.2e-09 36.8 0.9 4.8e-06 27.0 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG46504.1 - 1.9e-08 34.4 0.6 1.2e-07 31.8 0.4 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG46504.1 - 3.9e-08 33.8 1.0 7.9e-08 32.8 1.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG46504.1 - 4.1e-05 23.7 0.9 0.53 11.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEG46504.1 - 0.00017 21.8 1.4 0.041 14.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Choline_kinase PF01633.20 CEG46505.1 - 1.3e-55 188.3 0.1 1.9e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CEG46505.1 - 4.6e-12 46.4 0.0 1.6e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CEG46505.1 - 0.0059 16.0 0.1 0.0096 15.3 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Cellulose_synt PF03552.14 CEG46507.1 - 1.7e-22 79.8 3.8 1.2e-14 53.9 0.3 2.7 1 1 2 3 3 3 2 Cellulose synthase Glyco_trans_2_3 PF13632.6 CEG46507.1 - 1.3e-11 44.8 0.0 4.1e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEG46507.1 - 2.5e-09 37.3 0.0 9.4e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEG46507.1 - 5.4e-08 32.8 0.0 5.6e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ephrin_rec_like PF07699.13 CEG46507.1 - 0.00084 19.1 2.2 0.00084 19.1 2.2 16.5 12 8 9 22 22 22 2 Putative ephrin-receptor like Glyco_transf_21 PF13506.6 CEG46507.1 - 0.0025 17.3 0.0 1.7 8.1 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 zinc_ribbon_2 PF13240.6 CEG46507.1 - 1.6 8.6 10.9 0.33 10.7 2.1 5.0 4 0 0 4 4 4 0 zinc-ribbon domain TPR_1 PF00515.28 CEG46508.1 - 7.1e-52 171.2 31.0 9.7e-08 31.5 0.1 10.0 9 2 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CEG46508.1 - 5.7e-40 135.0 4.4 2.2e-21 75.5 0.2 2.9 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 CEG46508.1 - 2.6e-39 130.2 33.3 1.1e-06 28.2 0.1 10.5 9 2 1 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 CEG46508.1 - 9.4e-34 114.8 23.7 1.6e-10 40.5 0.2 9.1 7 3 3 10 10 10 4 TPR repeat TPR_8 PF13181.6 CEG46508.1 - 3.8e-26 89.1 34.9 5.6e-05 23.0 0.9 10.6 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 CEG46508.1 - 1.6e-19 70.0 19.6 6.5e-06 26.3 1.8 7.1 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEG46508.1 - 1.2e-17 62.9 15.5 0.0043 17.3 0.0 7.4 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEG46508.1 - 2.3e-17 63.4 10.1 0.00034 21.2 0.0 6.2 4 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG46508.1 - 1.7e-14 53.3 10.6 0.0053 17.5 0.0 9.2 4 3 6 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG46508.1 - 3.4e-13 48.6 7.0 0.028 14.4 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG46508.1 - 1.7e-08 34.4 1.3 0.41 10.8 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 CEG46508.1 - 7.7e-08 31.7 13.3 1.9e-05 23.8 9.0 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CEG46508.1 - 4.5e-07 29.5 17.8 0.061 13.2 0.1 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEG46508.1 - 1.6e-06 28.5 15.7 0.062 13.8 0.0 6.7 4 3 3 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 CEG46508.1 - 0.0039 16.5 7.7 0.49 9.6 0.3 4.4 2 2 3 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 CEG46508.1 - 0.0053 16.5 11.7 0.46 10.2 0.3 4.3 2 2 1 3 3 3 1 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 CEG46508.1 - 0.01 15.3 1.1 11 5.6 0.0 4.9 5 0 0 5 5 5 0 SHNi-TPR DUF3856 PF12968.7 CEG46508.1 - 0.024 14.7 7.4 12 5.9 0.3 4.6 2 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 CEG46508.1 - 0.026 13.9 3.9 0.35 10.2 0.8 3.2 2 1 2 4 4 4 0 MalT-like TPR region ANAPC3 PF12895.7 CEG46508.1 - 0.037 14.2 16.6 1.9 8.8 0.6 4.1 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L1 PF00687.21 CEG46508.1 - 0.052 13.3 0.6 0.27 10.9 0.0 2.3 3 1 1 4 4 3 0 Ribosomal protein L1p/L10e family Fis1_TPR_C PF14853.6 CEG46508.1 - 0.063 13.4 7.6 0.43 10.7 0.2 4.8 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Med9 PF07544.13 CEG46508.1 - 0.15 12.2 0.8 2.7 8.1 0.1 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 L31 PF09784.9 CEG46508.1 - 0.16 12.4 0.2 1.2 9.6 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Stathmin PF00836.19 CEG46508.1 - 0.17 11.8 9.3 0.25 11.3 1.4 2.5 2 0 0 2 2 2 0 Stathmin family BTAD PF03704.17 CEG46508.1 - 0.51 10.8 12.2 19 5.7 0.0 4.8 2 2 2 5 5 5 0 Bacterial transcriptional activator domain MIT PF04212.18 CEG46508.1 - 0.71 10.0 20.9 4.4 7.5 0.2 6.5 7 1 0 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CEG46508.1 - 5.3 7.1 14.4 16 5.6 0.1 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat UPF0220 PF05255.11 CEG46509.1 - 2.5e-19 69.5 3.4 3.6e-19 68.9 3.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) HEAT PF02985.22 CEG46510.1 - 1.2e-08 34.4 9.6 0.35 11.2 0.1 5.3 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 CEG46510.1 - 1.4e-07 31.9 1.0 0.00054 20.4 0.2 3.9 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 CEG46510.1 - 1.9e-05 25.0 0.7 1.5 9.3 0.2 3.8 3 1 1 4 4 4 3 HEAT repeats Vac14_Fab1_bd PF12755.7 CEG46510.1 - 9.1e-05 23.0 0.1 0.034 14.8 0.0 4.1 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEG46510.1 - 0.00015 21.4 0.1 2.3 7.7 0.0 3.9 3 1 0 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 CEG46510.1 - 0.0091 16.1 0.1 0.19 11.8 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 CEG46510.1 - 0.015 15.6 0.0 1.4 9.3 0.0 2.9 1 1 1 2 2 2 0 TAF6 C-terminal HEAT repeat domain RIX1 PF08167.12 CEG46510.1 - 0.02 14.6 0.0 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 CEG46510.1 - 0.035 12.7 0.2 3 6.3 0.1 2.6 1 1 1 2 2 2 0 Adaptin N terminal region DNTTIP1_dimer PF18192.1 CEG46510.1 - 0.067 13.6 0.2 0.99 9.8 0.1 2.6 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain RVT_1 PF00078.27 CEG46511.1 - 2.9e-06 26.9 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C53 PF05550.11 CEG46511.1 - 0.008 15.9 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Pestivirus Npro endopeptidase C53 RWP-RK PF02042.15 CEG46514.1 - 5.3e-19 67.9 0.1 1e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HAD_2 PF13419.6 CEG46514.1 - 0.029 14.5 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase tRNA-synt_1d PF00750.19 CEG46515.1 - 6.3e-117 390.4 0.3 1.2e-116 389.5 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CEG46515.1 - 4.5e-22 78.5 0.0 1.5e-21 76.8 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CEG46515.1 - 1e-16 61.3 3.1 9.6e-16 58.1 0.1 2.8 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CEG46515.1 - 0.0013 18.2 0.1 0.0028 17.1 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 CEG46515.1 - 0.0027 17.7 0.0 0.0081 16.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.22 CEG46515.1 - 0.015 13.6 0.0 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CEG46515.1 - 0.03 13.1 0.0 0.054 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (M) Aa_trans PF01490.18 CEG46517.1 - 1.4e-70 238.1 28.2 1.8e-70 237.7 28.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DoxX PF07681.12 CEG46517.1 - 0.023 15.2 0.6 0.11 13.0 0.6 2.3 1 0 0 1 1 1 0 DoxX Trypsin_2 PF13365.6 CEG46518.1 - 4.8e-18 66.5 0.1 1e-17 65.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 CEG46518.1 - 0.0003 19.6 2.3 0.0066 15.2 0.6 2.1 2 0 0 2 2 2 2 Peptidase S46 Linker_histone PF00538.19 CEG46519.1 - 3.3e-18 65.8 0.3 3.3e-18 65.8 0.3 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CEG46519.1 - 0.014 15.5 61.9 0.014 15.5 61.9 2.3 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 STD1 PF17235.2 CEG46522.1 - 0.0028 17.3 0.4 0.0032 17.1 0.4 1.1 1 0 0 1 1 1 1 STD1/MTH1 Nup88 PF10168.9 CEG46523.1 - 6.9e-14 50.6 13.0 3e-08 32.0 11.9 4.0 3 1 0 3 3 3 3 Nuclear pore component FAM76 PF16046.5 CEG46523.1 - 0.0047 16.3 5.1 0.0047 16.3 5.1 2.0 2 0 0 2 2 2 1 FAM76 protein Zn_clus PF00172.18 CEG46524.1 - 0.039 14.1 0.4 0.092 12.9 0.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Guanylate_cyc PF00211.20 CEG46525.1 - 4.9e-15 55.6 0.0 9.6e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NfeD PF01957.18 CEG46525.1 - 0.077 13.4 0.0 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4296 PF14129.6 CEG46526.1 - 9.3e-05 23.0 2.7 0.51 11.0 0.2 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4296) DUF2013 PF09431.10 CEG46528.1 - 7.1e-14 52.2 0.4 1.4e-13 51.2 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) SERTA PF06031.13 CEG46528.1 - 0.02 14.6 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 SERTA motif DUF4504 PF14953.6 CEG46529.1 - 2.8e-21 76.1 0.1 4.2e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) DUF1336 PF07059.12 CEG46530.1 - 6.8e-52 176.8 0.0 1.1e-51 176.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 CEG46530.1 - 1.3e-07 32.1 0.9 0.00092 19.7 0.1 2.8 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 CEG46530.1 - 0.00064 19.9 0.1 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CEG46530.1 - 0.09 13.2 2.6 0.31 11.5 2.6 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain TPK_catalytic PF04263.16 CEG46531.1 - 4.5e-37 126.8 0.2 9.7e-37 125.7 0.2 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain ATG_C PF09333.11 CEG46531.1 - 7.4e-30 103.2 0.1 3.2e-29 101.1 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CEG46531.1 - 2.4e-23 82.5 1.0 5.9e-23 81.2 0.4 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 TPK_B1_binding PF04265.14 CEG46531.1 - 4.9e-13 48.6 0.1 1e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain VPS13_C PF16909.5 CEG46531.1 - 0.00022 21.1 0.1 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 CEG46531.1 - 0.00077 19.2 0.1 0.0034 17.1 0.1 2.2 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif NDUFA12 PF05071.16 CEG46533.1 - 5.7e-15 55.9 0.6 5.7e-15 55.9 0.6 1.7 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Glyco_hydro_57 PF03065.15 CEG46535.1 - 0.041 13.1 0.1 0.047 12.9 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 T3SS_needle_E PF08988.10 CEG46536.1 - 0.28 11.4 0.2 0.28 11.4 0.2 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Ammonium_transp PF00909.21 CEG46540.1 - 8.2e-27 93.9 0.5 9.1e-27 93.8 0.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family IQ PF00612.27 CEG46541.1 - 0.0003 20.3 12.9 0.036 13.9 0.2 4.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif cNMP_binding PF00027.29 CEG46542.1 - 1.4e-62 207.8 0.5 7.8e-21 74.0 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 CEG46542.1 - 3.1e-62 210.3 0.0 5.2e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HECT PF00632.25 CEG46542.1 - 2.4e-37 129.1 0.0 8.9e-24 84.5 0.0 3.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Pkinase_Tyr PF07714.17 CEG46542.1 - 9.1e-30 103.8 0.0 1.7e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_DE_N PF02823.16 CEG46542.1 - 0.06 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2740 PF10872.8 CEG46542.1 - 0.19 11.6 0.8 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) KIAA1430 PF13879.6 CEG46543.1 - 0.0027 18.4 0.4 0.0027 18.4 0.4 5.2 3 1 1 5 5 5 2 KIAA1430 homologue Baculo_PEP_C PF04513.12 CEG46543.1 - 2 8.4 8.7 5.8 6.9 0.4 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 CEG46543.1 - 5.8 7.0 29.7 0.63 10.1 4.2 4.4 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 CEG46543.1 - 8.4 6.9 11.9 20 5.7 0.1 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Asp_Arg_Hydrox PF05118.15 CEG46544.1 - 2.8e-10 40.2 0.3 6.1e-10 39.1 0.3 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_1 PF00685.27 CEG46544.1 - 8.4e-09 35.3 0.1 8.9e-08 31.9 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEG46544.1 - 7.8e-06 26.4 0.1 0.00077 19.9 0.1 3.1 2 1 0 2 2 2 1 Sulfotransferase family Ribosomal_L18 PF17135.4 CEG46545.1 - 1.3e-83 279.1 3.4 1.4e-83 278.9 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CEG46545.1 - 0.0013 19.4 0.2 0.0036 18.0 0.2 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sigma54_DBD PF04552.13 CEG46545.1 - 0.059 13.1 0.1 2.4 7.9 0.0 2.1 1 1 1 2 2 2 0 Sigma-54, DNA binding domain SIN1_PH PF16979.5 CEG46546.1 - 3.3e-17 62.7 0.7 7.7e-17 61.6 0.7 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 CEG46546.1 - 1e-08 35.5 0.0 3.8e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RA PF00788.23 CEG46546.1 - 0.026 15.2 0.1 2.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain CdiI_2 PF18593.1 CEG46546.1 - 0.15 12.7 0.0 0.47 11.1 0.0 1.9 1 0 0 1 1 1 0 CdiI immunity protein NTP_transferase PF00483.23 CEG46547.1 - 2.5e-10 40.4 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEG46547.1 - 1e-06 28.2 12.9 2.1e-05 24.0 2.5 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CEG46547.1 - 0.0035 15.6 0.4 0.0051 15.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 CEG46547.1 - 0.0039 17.5 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CEG46547.1 - 1.5 8.6 5.3 6.8 6.5 2.0 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Amidinotransf PF02274.17 CEG46548.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase RVT_1 PF00078.27 CEG46554.1 - 2.8e-06 27.0 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3-RhoG_link PF16609.5 CEG46554.1 - 0.0087 15.8 1.9 0.014 15.2 1.9 1.2 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region DUF1554 PF07588.11 CEG46554.1 - 0.021 14.6 0.7 0.2 11.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1554) Mrr_cat PF04471.12 CEG46554.1 - 0.066 13.2 0.0 9.4 6.3 0.0 2.5 1 1 1 2 2 2 0 Restriction endonuclease Pur_DNA_glyco PF02245.16 CEG46554.1 - 0.18 11.3 0.1 0.35 10.3 0.1 1.4 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) FYVE PF01363.21 CEG46556.1 - 1.8e-07 31.2 9.1 1.8e-07 31.2 9.1 1.7 2 0 0 2 2 2 1 FYVE zinc finger fn3 PF00041.21 CEG46556.1 - 0.015 15.6 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain FYVE_2 PF02318.16 CEG46556.1 - 0.023 14.9 3.5 0.023 14.9 3.5 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zinc-ribbons_6 PF07191.12 CEG46556.1 - 0.03 14.3 2.9 0.03 14.3 2.9 2.2 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CEG46556.1 - 0.97 9.5 6.9 1 9.4 4.0 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CEG46556.1 - 2 8.0 7.1 2.7 7.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain ADD_ATRX PF17981.1 CEG46556.1 - 2.4 8.1 9.3 21 5.1 5.4 2.5 2 0 0 2 2 2 0 Cysteine Rich ADD domain HypA PF01155.19 CEG46556.1 - 3.8 7.6 7.1 6.6 6.8 4.0 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2039 PF10217.9 CEG46556.1 - 5.1 7.5 9.3 20 5.6 5.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.10 CEG46556.1 - 6.8 6.9 9.0 11 6.2 6.3 2.7 2 1 0 2 2 2 0 Zinc ribbon domain GSHPx PF00255.19 CEG46558.1 - 1.8e-40 136.9 0.7 3.6e-40 135.9 0.7 1.6 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEG46558.1 - 1.9e-10 40.7 0.1 5.5e-10 39.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEG46558.1 - 0.00029 20.6 0.0 0.00097 18.9 0.0 1.9 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 CEG46559.1 - 3.4e-21 74.8 0.0 6.2e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase Mito_carr PF00153.27 CEG46560.1 - 2.1e-48 162.2 7.1 7.5e-16 57.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 CEG46563.1 - 6.6e-28 97.1 1.4 3.5e-16 59.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG46563.1 - 2.4e-18 66.3 2.3 1.6e-12 47.7 0.3 3.4 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG46563.1 - 7.1e-17 61.3 3.0 4e-09 36.6 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEG46563.1 - 6.1e-15 54.9 6.6 8.3e-07 29.2 0.5 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CEG46563.1 - 1.2e-09 37.6 3.7 0.0017 18.7 0.2 3.6 4 0 0 4 4 4 2 Ankyrin repeat Aminotran_1_2 PF00155.21 CEG46564.1 - 1e-42 146.7 0.0 1.2e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG46564.1 - 0.00022 20.3 0.0 0.00082 18.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 CEG46564.1 - 0.0009 18.1 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 CEG46564.1 - 0.0018 16.9 0.0 0.003 16.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 CEG46564.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Aminotran_3 PF00202.21 CEG46564.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.5 1 1 1 2 2 2 0 Aminotransferase class-III Beta_elim_lyase PF01212.21 CEG46564.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEG46564.1 - 0.21 10.9 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family CRAL_TRIO_2 PF13716.6 CEG46567.1 - 0.048 13.8 0.1 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Nuc_rec_co-act PF08815.10 CEG46567.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Nuclear receptor coactivator DnaJ_CXXCXGXG PF00684.19 CEG46568.1 - 8.4e-05 22.9 4.8 0.00014 22.1 4.6 1.6 1 1 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 CEG46568.1 - 0.028 14.1 5.1 0.25 11.1 0.7 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF5351 PF17302.2 CEG46568.1 - 3.3 8.0 9.3 11 6.4 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5351) HSF_DNA-bind PF00447.17 CEG46569.1 - 4.6e-19 68.8 0.8 1e-18 67.7 0.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 CEG46570.1 - 1e-42 146.3 0.0 4.5e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46570.1 - 1.1e-40 139.6 0.0 1.5e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2269 PF10027.9 CEG46570.1 - 0.017 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Haspin_kinase PF12330.8 CEG46570.1 - 0.083 11.8 5.8 0.79 8.6 0.0 2.4 2 1 0 2 2 2 0 Haspin like kinase domain Tankyrase_bdg_C PF15327.6 CEG46572.1 - 0.017 15.6 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain NikR_C PF08753.11 CEG46572.1 - 0.056 13.6 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 NikR C terminal nickel binding domain BSD PF03909.17 CEG46574.1 - 9.8e-07 28.7 0.2 3.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 BSD domain DUF4577 PF15145.6 CEG46575.1 - 0.064 13.3 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Retrotran_gag_2 PF14223.6 CEG46576.1 - 1.6e-36 125.0 0.1 2.5e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF188 PF02639.14 CEG46576.1 - 0.07 12.8 0.4 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF4219 PF13961.6 CEG46576.1 - 0.14 11.9 0.5 0.42 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Spore_YunB PF09560.10 CEG46577.1 - 0.076 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) DUF4136 PF13590.6 CEG46578.1 - 0.015 15.9 0.0 0.038 14.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) Dynein_light PF01221.18 CEG46580.1 - 1.9e-25 89.0 0.4 2.2e-25 88.8 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 MatP PF06303.12 CEG46580.1 - 0.046 14.3 0.1 0.064 13.8 0.1 1.1 1 0 0 1 1 1 0 MatP N-terminal domain COQ7 PF03232.13 CEG46581.1 - 1.1e-14 54.6 0.0 1.3e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 AAA_10 PF12846.7 CEG46582.1 - 0.00075 18.5 0.0 0.00075 18.5 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_25 PF13481.6 CEG46582.1 - 0.002 17.7 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CEG46582.1 - 0.016 15.3 0.1 0.021 14.9 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 CEG46582.1 - 0.021 14.6 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 CEG46582.1 - 0.047 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.14 CEG46582.1 - 0.056 13.4 0.2 0.098 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CEG46582.1 - 0.07 13.0 0.2 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CEG46582.1 - 0.12 12.9 0.1 0.15 12.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CEG46582.1 - 0.14 12.4 0.1 0.16 12.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEG46582.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CEG46582.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEG46582.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase PBP PF01161.20 CEG46583.1 - 5.1e-12 46.2 0.1 8.3e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 CEG46584.1 - 1.8e-29 102.9 0.1 1.9e-28 99.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46584.1 - 2.9e-12 46.4 0.4 3.1e-10 39.8 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5365 PF17326.2 CEG46584.1 - 0.039 14.3 2.1 0.28 11.6 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5365) APH PF01636.23 CEG46584.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PseudoU_synth_2 PF00849.22 CEG46585.1 - 4e-21 75.8 0.0 6.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase FlgO PF17680.1 CEG46585.1 - 0.039 13.7 0.1 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 FlgO protein Chromo PF00385.24 CEG46589.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain GDA1_CD39 PF01150.17 CEG46590.1 - 0.052 12.2 0.1 0.052 12.2 0.1 1.0 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family ABC_tran PF00005.27 CEG46591.1 - 2.7e-27 95.9 0.0 5.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CEG46591.1 - 9.3e-26 91.1 8.6 2e-25 90.0 8.6 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CEG46591.1 - 2.6e-07 30.3 0.1 1.2e-05 24.8 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG46591.1 - 2.9e-05 24.5 0.1 0.00016 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG46591.1 - 0.00021 21.6 0.1 0.057 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CEG46591.1 - 0.0012 18.7 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEG46591.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CEG46591.1 - 0.0043 16.7 0.0 0.066 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEG46591.1 - 0.0061 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 CEG46591.1 - 0.01 16.3 0.0 0.13 12.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CEG46591.1 - 0.04 12.7 0.2 4.7 5.9 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 CEG46591.1 - 0.05 14.1 0.0 0.097 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CEG46591.1 - 0.059 13.1 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 CEG46591.1 - 0.06 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CEG46591.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 CEG46591.1 - 0.11 12.8 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 CEG46591.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 CEG46591.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_30 PF13604.6 CEG46591.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain PH PF00169.29 CEG46592.1 - 9.9e-07 29.2 0.1 3.9e-06 27.3 0.0 2.1 2 0 0 2 2 1 1 PH domain Seryl_tRNA_N PF02403.22 CEG46592.1 - 0.0001 22.5 40.2 0.096 12.9 1.2 4.6 3 1 1 4 4 4 3 Seryl-tRNA synthetase N-terminal domain WW PF00397.26 CEG46592.1 - 0.00016 21.7 1.1 0.00038 20.5 1.1 1.7 1 0 0 1 1 1 1 WW domain PH_6 PF15406.6 CEG46592.1 - 0.00077 19.7 1.5 0.002 18.4 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain ABC_tran_CTD PF16326.5 CEG46592.1 - 0.006 16.8 5.5 0.006 16.8 5.5 5.1 3 1 1 4 4 4 1 ABC transporter C-terminal domain GTP-bdg_M PF16360.5 CEG46592.1 - 0.029 15.0 1.3 0.029 15.0 1.3 4.9 5 0 0 5 5 5 0 GTP-binding GTPase Middle Region PH_11 PF15413.6 CEG46592.1 - 0.16 12.4 0.2 0.16 12.4 0.2 4.3 4 2 1 5 5 5 0 Pleckstrin homology domain APG6_N PF17675.1 CEG46592.1 - 0.19 12.3 49.5 0.044 14.3 18.3 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Flagellin_C PF00700.21 CEG46592.1 - 1.4 9.3 8.4 0.14 12.6 1.5 2.9 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4763 PF15960.5 CEG46592.1 - 6.6 6.0 26.4 0.37 10.1 10.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Taxilin PF09728.9 CEG46592.1 - 7 5.7 46.6 1.3 8.1 5.5 4.3 2 1 2 4 4 4 0 Myosin-like coiled-coil protein GAS PF13851.6 CEG46592.1 - 7.6 5.8 42.0 1.8 7.9 4.7 4.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Retrotran_gag_2 PF14223.6 CEG46593.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CEG46593.1 - 0.17 11.6 0.7 0.31 10.8 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Ycf54 PF10674.9 CEG46596.1 - 0.012 15.8 0.1 0.065 13.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) Peptidase_M20 PF01546.28 CEG46597.1 - 6.4e-30 104.4 0.0 8.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEG46597.1 - 1.2e-11 44.4 0.0 2.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CEG46597.1 - 0.0031 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 CEG46598.1 - 2.2e-132 440.3 0.0 1.1e-66 224.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46598.1 - 4.1e-55 186.8 0.0 4.1e-27 95.1 0.1 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 CEG46598.1 - 4.4e-14 52.3 0.6 1.4e-06 28.3 0.2 2.6 2 0 0 2 2 2 2 WW domain Haspin_kinase PF12330.8 CEG46598.1 - 3.7e-10 39.3 0.1 0.00015 20.8 0.0 2.7 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 CEG46598.1 - 5.5e-08 32.5 0.0 0.013 14.9 0.0 3.4 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 CEG46598.1 - 3.5e-07 30.4 0.6 0.046 13.6 0.1 3.1 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CEG46598.1 - 6.2e-07 29.0 2.5 0.011 15.0 0.3 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEG46598.1 - 4.1e-06 26.5 0.2 0.026 14.1 0.0 3.1 3 0 0 3 3 3 2 RIO1 family FTA2 PF13095.6 CEG46598.1 - 0.012 15.2 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CEG46598.1 - 0.11 12.1 2.3 6.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase PTS_2-RNA PF01885.16 CEG46600.1 - 3.1e-14 53.4 0.0 4e-14 53.1 0.0 1.3 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Apc13p PF05839.11 CEG46601.1 - 4.9e-06 26.6 5.5 3.8e-05 23.8 5.5 1.9 1 1 0 1 1 1 1 Apc13p protein Pkinase_Tyr PF07714.17 CEG46602.1 - 1.5e-57 194.9 0.0 1.8e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG46602.1 - 3.2e-52 177.5 0.0 4.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEG46602.1 - 3e-05 23.5 0.0 0.00022 20.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEG46602.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CEG46602.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Dcc1 PF09724.9 CEG46603.1 - 1.2e-81 274.6 1.5 1.4e-81 274.4 1.5 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RICTOR_V PF14668.6 CEG46604.1 - 0.0093 16.2 0.6 0.032 14.4 0.1 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 Utp21 PF04192.12 CEG46604.1 - 0.098 12.1 0.2 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Tmemb_55A PF09788.9 CEG46605.1 - 0.015 14.4 0.1 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2613 PF11021.8 CEG46605.1 - 0.31 11.2 2.6 0.85 9.8 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) Trypsin_2 PF13365.6 CEG46606.1 - 1.9e-11 45.1 0.0 5.2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG46606.1 - 0.014 15.3 2.6 0.28 11.0 2.6 2.3 1 1 0 1 1 1 0 Trypsin Peptidase_S46 PF10459.9 CEG46606.1 - 0.26 9.9 0.7 0.37 9.4 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 adh_short PF00106.25 CEG46607.1 - 9.2e-43 146.0 0.1 1.3e-42 145.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG46607.1 - 1e-26 94.0 0.0 1.4e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CEG46607.1 - 0.00014 21.3 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CEG46607.1 - 0.019 14.9 0.1 0.061 13.2 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 CEG46607.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 KR domain C2 PF00168.30 CEG46609.1 - 9.1e-16 58.0 0.1 2.3e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 C2 domain Cys_rich_KTR PF14205.6 CEG46609.1 - 0.28 11.0 0.8 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR adh_short PF00106.25 CEG46610.1 - 1.9e-43 148.2 0.8 2.3e-43 147.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG46610.1 - 1.2e-26 93.8 0.3 1.6e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG46610.1 - 1.8e-13 50.8 1.4 2e-13 50.7 0.5 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CEG46610.1 - 1.5e-05 24.3 0.1 2.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3842 PF12953.7 CEG46610.1 - 0.019 15.3 1.4 0.078 13.4 1.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3842) Ldh_1_N PF00056.23 CEG46610.1 - 0.025 14.7 0.3 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TSC22 PF01166.18 CEG46611.1 - 0.36 11.2 5.8 6.6 7.1 1.4 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family BBL5 PF07289.11 CEG46612.1 - 4.3e-44 150.9 0.0 4.7e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein GnsAB_toxin PF08178.11 CEG46613.1 - 0.062 13.2 0.2 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Methyltr_RsmB-F PF01189.17 CEG46614.1 - 2.8e-39 134.9 0.0 4e-20 72.3 0.0 2.3 1 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 CEG46614.1 - 8.7e-08 32.0 0.2 2.4e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.19 CEG46614.1 - 6.2e-05 23.2 0.0 0.00032 20.8 0.0 2.1 2 1 0 2 2 2 1 FtsJ-like methyltransferase Pro-rich_19 PF15455.6 CEG46614.1 - 0.0063 15.7 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Proline-rich 19 Fibrillarin PF01269.17 CEG46614.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DUF5048 PF16467.5 CEG46614.1 - 0.098 12.9 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5048) Methyltransf_25 PF13649.6 CEG46614.1 - 0.1 13.3 0.0 0.48 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmF_N PF17125.5 CEG46614.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF UPF0160 PF03690.13 CEG46615.1 - 4.8e-102 341.8 0.1 5.9e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.8 CEG46615.1 - 0.00054 19.8 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase N terminal Bromo_MP PF01573.16 CEG46615.1 - 0.059 12.7 0.0 0.76 9.1 0.0 2.1 1 1 1 2 2 2 0 Bromovirus movement protein zf-LYAR PF08790.11 CEG46618.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Spore_IV_A PF09547.10 CEG46620.1 - 0.033 13.1 0.0 0.033 13.1 0.0 1.0 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) N-SET PF11764.8 CEG46620.1 - 0.081 13.0 0.1 0.095 12.8 0.1 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N AIP3 PF03915.13 CEG46621.1 - 0.0058 15.8 0.1 0.0086 15.2 0.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Focal_AT PF03623.13 CEG46621.1 - 0.018 15.1 0.0 0.39 10.7 0.0 2.3 1 1 1 2 2 2 0 Focal adhesion targeting region Cauli_AT PF03233.13 CEG46621.1 - 0.035 14.1 1.0 0.097 12.6 0.5 1.9 1 1 1 2 2 2 0 Aphid transmission protein DUF1451 PF07295.11 CEG46621.1 - 0.043 13.8 0.2 0.14 12.2 0.1 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain Tweety PF04906.13 CEG46621.1 - 0.066 11.9 0.5 0.097 11.3 0.5 1.2 1 0 0 1 1 1 0 Tweety ApoLp-III PF07464.11 CEG46621.1 - 0.11 12.6 0.6 1 9.4 0.3 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.10 CEG46621.1 - 2.5 8.3 7.5 0.66 10.2 3.2 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 CEG46622.1 - 0.0026 17.7 0.2 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 CEG46622.1 - 0.03 14.6 1.6 0.08 13.3 1.6 1.7 1 0 0 1 1 1 0 MT0933-like antitoxin protein Remorin_C PF03763.13 CEG46622.1 - 0.14 12.1 1.3 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Remorin, C-terminal region Osmo_CC PF08946.10 CEG46622.1 - 0.37 11.1 1.6 20 5.5 0.0 3.8 3 1 1 4 4 4 0 Osmosensory transporter coiled coil DUF5570 PF17731.1 CEG46625.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5570) Glyco_hydro_30 PF02055.16 CEG46626.1 - 2.3e-96 322.8 1.2 2.8e-96 322.5 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CEG46626.1 - 2.2e-12 47.0 0.0 4.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain YHS PF04945.13 CEG46627.1 - 0.1 12.7 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 YHS domain zf-H2C2_2 PF13465.6 CEG46627.1 - 0.42 11.1 1.8 37 5.0 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Beach PF02138.18 CEG46630.1 - 1.7e-118 395.0 0.0 2.6e-118 394.4 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Peptidase_M8 PF01457.16 CEG46630.1 - 3.8e-40 138.1 0.0 6.1e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Leishmanolysin WD40 PF00400.32 CEG46630.1 - 1.2e-09 38.6 6.0 0.0003 21.5 0.0 5.2 3 1 1 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.6 CEG46630.1 - 1.1e-06 28.6 0.1 1.6e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH EGF_2 PF07974.13 CEG46631.1 - 4.6e-22 78.1 135.2 0.0001 22.6 9.9 10.0 10 0 0 10 10 10 8 EGF-like domain Peptidase_M8 PF01457.16 CEG46631.1 - 1.6e-13 50.2 2.4 3.6e-13 49.1 2.4 1.6 1 0 0 1 1 1 1 Leishmanolysin EGF PF00008.27 CEG46631.1 - 0.0091 16.3 5.0 0.0091 16.3 5.0 10.1 8 1 1 9 9 9 4 EGF-like domain DUF2534 PF10749.9 CEG46631.1 - 0.031 14.4 0.2 0.065 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) PIN_3 PF13470.6 CEG46631.1 - 0.073 13.8 0.0 0.75 10.6 0.0 2.2 2 0 0 2 2 2 0 PIN domain BetaGal_dom2 PF10435.9 CEG46631.1 - 0.082 12.7 2.2 1.4 8.7 0.1 2.7 2 1 1 3 3 3 0 Beta-galactosidase, domain 2 DUF2207 PF09972.9 CEG46631.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ADH_zinc_N PF00107.26 CEG46633.1 - 0.0028 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-BED PF02892.15 CEG46633.1 - 0.0029 17.6 2.3 0.0067 16.4 2.3 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 CEG46633.1 - 0.3 12.1 3.7 0.84 10.6 3.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger RraA-like PF03737.15 CEG46634.1 - 2e-29 102.7 4.1 2.6e-29 102.3 4.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Retrotran_gag_2 PF14223.6 CEG46637.1 - 1.6e-10 40.8 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 CEG46639.1 - 5.4e-16 59.0 0.3 7.4e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAP PF00956.18 CEG46642.1 - 4.9e-17 62.0 12.8 7.9e-16 58.0 3.0 3.9 2 2 2 4 4 4 3 Nucleosome assembly protein (NAP) SspO PF08175.12 CEG46642.1 - 0.022 15.2 0.8 0.061 13.8 0.8 1.7 1 0 0 1 1 1 0 Small acid-soluble spore protein O family ACAS_N PF16177.5 CEG46642.1 - 0.64 10.0 4.0 0.57 10.1 0.7 2.6 2 1 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus NOA36 PF06524.12 CEG46642.1 - 3.9 6.7 15.8 5.5 6.2 15.8 1.2 1 0 0 1 1 1 0 NOA36 protein Pirin_C_2 PF17954.1 CEG46643.1 - 0.091 12.9 0.5 3 8.1 0.0 2.2 1 1 1 2 2 2 0 Quercetinase C-terminal cupin domain Rep_trans PF02486.19 CEG46644.1 - 0.012 15.4 1.4 0.045 13.5 0.6 2.0 1 1 0 1 1 1 0 Replication initiation factor BEX PF04538.12 CEG46645.1 - 0.092 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family cNMP_binding PF00027.29 CEG46647.1 - 0.018 15.1 0.2 0.076 13.1 0.0 2.2 3 0 0 3 3 3 0 Cyclic nucleotide-binding domain PUF PF00806.19 CEG46648.1 - 1.1e-09 37.5 0.0 0.36 10.6 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat SNF2_N PF00176.23 CEG46649.1 - 4e-71 239.6 1.5 7.2e-71 238.7 0.6 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CEG46649.1 - 7.2e-37 125.9 0.6 2.9e-36 124.0 0.6 2.2 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 CEG46649.1 - 2e-21 76.4 0.0 8.2e-21 74.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG46649.1 - 6.6e-07 29.5 0.0 6.6e-07 29.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HAND PF09110.11 CEG46649.1 - 3.9e-05 24.4 6.8 3.9e-05 24.4 6.8 2.9 2 0 0 2 2 2 1 HAND DEAD PF00270.29 CEG46649.1 - 8.9e-05 22.3 1.0 0.00062 19.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_14 PF13173.6 CEG46649.1 - 0.0065 16.5 0.2 0.039 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 CEG46649.1 - 0.0067 16.3 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DGOK PF05035.12 CEG46651.1 - 0.16 10.8 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase WD40 PF00400.32 CEG46652.1 - 2.2e-16 59.9 3.5 0.0076 17.1 0.1 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CEG46652.1 - 4.9e-06 25.5 1.1 0.0072 15.0 0.1 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEG46652.1 - 0.01 14.9 3.8 0.21 10.5 0.4 2.8 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein bPH_1 PF08000.11 CEG46652.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain MraZ PF02381.18 CEG46652.1 - 0.21 11.6 0.1 1.6 8.8 0.2 2.1 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like Methyltransf_28 PF02636.17 CEG46653.1 - 1.9e-06 27.7 0.0 0.0098 15.5 0.0 2.2 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_2 PF07719.17 CEG46653.1 - 4e-05 23.4 6.4 0.0035 17.4 1.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG46653.1 - 4.4e-05 23.1 4.6 0.004 16.9 0.8 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG46653.1 - 0.0053 17.0 2.9 0.02 15.1 2.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG46653.1 - 0.04 14.1 3.1 0.41 11.0 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2706 PF10913.8 CEG46655.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2706) GDP_Man_Dehyd PF16363.5 CEG46658.1 - 4.5e-60 203.8 0.0 1.3e-59 202.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEG46658.1 - 1.4e-52 178.6 0.0 1.7e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEG46658.1 - 1e-20 73.9 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEG46658.1 - 2.5e-19 69.5 0.0 2.3e-18 66.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEG46658.1 - 9.1e-16 57.8 0.0 1.7e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CEG46658.1 - 1.1e-08 34.5 0.0 2.2e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CEG46658.1 - 3.8e-06 26.9 0.1 1.4e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CEG46658.1 - 7.9e-05 22.2 0.0 0.00044 19.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CEG46658.1 - 0.00012 22.1 0.1 0.00042 20.3 0.1 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 CEG46658.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.6 CEG46658.1 - 0.036 13.6 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MIR PF02815.19 CEG46660.1 - 0.04 13.8 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 MIR domain rve PF00665.26 CEG46661.1 - 1.5e-18 67.1 0.0 3.4e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CEG46661.1 - 1.7e-05 24.5 0.1 3.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEG46661.1 - 0.0016 18.3 0.0 0.0055 16.6 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dicer_dimer PF03368.14 CEG46661.1 - 0.057 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Dicer dimerisation domain 5_nucleotid_C PF02872.18 CEG46663.1 - 0.081 13.1 1.2 0.28 11.4 0.2 2.1 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain ubiquitin PF00240.23 CEG46667.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DWNN PF08783.11 CEG46667.1 - 0.14 12.5 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 DWNN domain ABC2_membrane PF01061.24 CEG46668.1 - 5.1e-70 235.1 52.9 2.5e-39 134.9 17.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CEG46668.1 - 1.3e-32 113.2 0.0 2.5e-16 60.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CEG46668.1 - 5.2e-07 29.3 0.5 0.0089 15.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG46668.1 - 2.8e-06 27.3 0.1 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase PDR_assoc PF08370.11 CEG46668.1 - 1.3e-05 24.9 0.5 8.1e-05 22.3 0.5 2.4 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_22 PF13401.6 CEG46668.1 - 3.5e-05 24.1 0.0 0.45 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 CEG46668.1 - 4e-05 22.9 12.8 4e-05 22.9 12.8 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_23 PF13476.6 CEG46668.1 - 0.00011 22.8 0.8 0.1 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEG46668.1 - 0.00014 21.5 0.1 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CEG46668.1 - 0.00067 19.6 1.2 3 7.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CEG46668.1 - 0.00068 19.7 0.2 1.6 8.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 CEG46668.1 - 0.0024 17.6 3.3 0.57 9.9 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG46668.1 - 0.0032 18.0 0.1 1.7 9.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG46668.1 - 0.0035 17.8 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEG46668.1 - 0.0089 16.2 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CEG46668.1 - 0.013 15.5 1.6 0.51 10.3 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CEG46668.1 - 0.023 14.9 0.2 1.3 9.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CEG46668.1 - 0.024 13.9 1.3 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 CEG46668.1 - 0.026 14.9 1.0 13 6.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CEG46668.1 - 0.04 13.5 1.4 2.4 7.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 CEG46668.1 - 0.043 13.1 0.2 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SMC_N PF02463.19 CEG46668.1 - 0.045 13.2 0.2 7.5 5.9 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CEG46668.1 - 0.1 12.7 3.8 2.5 8.2 0.7 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 CEG46668.1 - 0.12 12.1 1.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEG46668.1 - 0.13 12.1 3.5 3.6 7.5 0.6 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CEG46668.1 - 0.14 12.5 0.5 29 5.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MeaB PF03308.16 CEG46668.1 - 0.15 11.0 0.9 4.8 6.1 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 CEG46668.1 - 0.17 11.8 0.9 13 5.7 0.2 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 CEG46668.1 - 0.21 11.5 2.2 4.7 7.1 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 CEG46668.1 - 0.22 11.9 3.4 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 CEG46668.1 - 0.95 9.4 13.3 0.097 12.6 0.3 3.4 3 0 0 3 3 2 0 CDR ABC transporter TEA PF01285.18 CEG46669.1 - 8.7e-05 22.5 0.6 0.00023 21.2 0.6 1.7 1 0 0 1 1 1 1 TEA/ATTS domain WD40 PF00400.32 CEG46669.1 - 0.17 12.8 0.1 1.6 9.7 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat LVIVD PF08309.11 CEG46669.1 - 0.19 11.1 2.8 0.12 11.7 0.3 2.0 2 0 0 2 2 2 0 LVIVD repeat IF-2B PF01008.17 CEG46670.1 - 1.8e-70 237.4 0.0 2.6e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lactamase_B_2 PF12706.7 CEG46671.1 - 1.3e-16 60.8 0.5 1.2e-14 54.3 0.0 3.4 3 2 1 4 4 4 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CEG46671.1 - 1.3e-16 60.0 0.1 3.5e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 CEG46671.1 - 0.068 13.2 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily PhoLip_ATPase_C PF16212.5 CEG46672.1 - 8.3e-68 228.8 27.9 8.3e-68 228.8 27.9 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG46672.1 - 4.3e-20 71.2 3.3 4.3e-20 71.2 3.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEG46672.1 - 2.3e-11 43.6 0.0 6.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG46672.1 - 1.3e-10 42.0 0.8 1.3e-06 28.9 0.2 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG46672.1 - 5.7e-07 29.2 0.6 4.8e-06 26.2 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG46672.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKBP26_C PF18046.1 CEG46673.1 - 0.049 13.7 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 FKBP26_C-terminal WD40 PF00400.32 CEG46674.1 - 4.3e-19 68.5 9.1 4.5e-05 24.1 1.2 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46674.1 - 1.1e-09 38.4 0.0 0.01 16.1 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG46674.1 - 0.0013 17.5 0.0 0.064 11.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CEG46674.1 - 0.013 15.1 0.2 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 PQQ-like domain DUF4097 PF13349.6 CEG46675.1 - 0.0042 16.5 7.6 0.023 14.1 6.8 2.8 1 1 1 2 2 2 1 Putative adhesin Lipase_3 PF01764.25 CEG46678.1 - 1.2e-18 67.4 0.0 2.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 CEG46678.1 - 5.4e-17 61.7 26.0 9.2e-12 44.9 10.3 2.5 2 0 0 2 2 2 2 FYVE zinc finger Rpr2 PF04032.16 CEG46678.1 - 0.007 16.6 10.2 0.096 13.0 3.8 3.7 3 1 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pro-rich_19 PF15455.6 CEG46680.1 - 0.11 11.6 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Proline-rich 19 NAD_binding_4 PF07993.12 CEG46681.1 - 7.5e-67 225.2 0.0 1.8e-66 223.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Acyltransferase PF01553.21 CEG46681.1 - 4e-19 68.6 0.0 9.1e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 CEG46681.1 - 8.4e-13 48.4 0.2 2.1e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 Male sterility protein SelB-wing_2 PF09106.11 CEG46681.1 - 0.017 15.3 0.1 51 4.2 0.1 3.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix 3Beta_HSD PF01073.19 CEG46681.1 - 0.18 10.8 0.0 0.69 8.9 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCHC PF00098.23 CEG46682.1 - 0.00052 20.0 1.1 0.0018 18.2 1.1 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEG46682.1 - 0.073 12.8 1.0 0.14 11.9 1.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CEG46682.1 - 0.11 12.4 0.7 0.24 11.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 CEG46687.1 - 7.1e-13 48.7 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-GRF PF06839.12 CEG46687.1 - 9.8e-11 41.6 0.9 2.2e-10 40.4 0.9 1.6 1 0 0 1 1 1 1 GRF zinc finger Helicase_C PF00271.31 CEG46687.1 - 8.1e-05 22.9 0.0 0.0016 18.7 0.1 2.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG46687.1 - 0.022 14.7 0.0 0.25 11.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HD_3 PF13023.6 CEG46688.1 - 1.2e-47 161.9 0.3 1.4e-47 161.6 0.3 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CEG46688.1 - 6.8e-13 48.8 0.2 8.5e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CEG46688.1 - 8.4e-05 22.8 0.2 0.00013 22.1 0.2 1.3 1 0 0 1 1 1 1 HD domain 2-Hacid_dh PF00389.30 CEG46688.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ADK PF00406.22 CEG46689.1 - 3.6e-59 199.2 0.0 4.6e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG46689.1 - 5.2e-25 88.5 0.0 1.4e-24 87.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CEG46689.1 - 1e-17 63.8 0.0 1.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CEG46689.1 - 1.4e-06 28.5 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG46689.1 - 0.02 15.4 0.0 0.061 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ammonium_transp PF00909.21 CEG46691.1 - 1.5e-43 149.0 4.6 1.8e-43 148.7 4.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Kinocilin PF15033.6 CEG46691.1 - 0.0015 18.2 0.6 0.0029 17.2 0.6 1.5 1 0 0 1 1 1 1 Kinocilin protein Corona_M PF01635.18 CEG46691.1 - 0.022 14.1 1.4 0.029 13.7 0.6 1.6 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Vma12 PF11712.8 CEG46691.1 - 0.031 14.3 0.9 0.07 13.2 0.9 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pam17 PF08566.10 CEG46691.1 - 0.9 9.4 6.1 3.3 7.5 0.7 3.2 2 2 0 3 3 3 0 Mitochondrial import protein Pam17 FYVE PF01363.21 CEG46692.1 - 0.64 10.2 13.3 1.2 9.3 13.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG46692.1 - 1.3 9.3 13.5 3 8.1 13.5 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger DUF2039 PF10217.9 CEG46692.1 - 1.5 9.2 10.5 0.33 11.3 7.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF2039 PF10217.9 CEG46693.1 - 0.017 15.4 4.8 0.017 15.4 4.8 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) FYVE PF01363.21 CEG46693.1 - 0.025 14.7 12.0 0.045 13.9 12.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 CEG46693.1 - 0.45 10.8 6.1 0.52 10.6 4.0 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CEG46693.1 - 0.71 10.1 8.9 1.5 9.1 8.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger WD40 PF00400.32 CEG46694.1 - 1.1e-22 79.8 11.7 4.5e-07 30.4 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46694.1 - 3.4e-08 33.7 0.2 0.31 11.4 0.1 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG46694.1 - 0.0091 15.4 0.1 0.32 10.3 0.2 2.7 1 1 1 2 2 2 1 WD40-like domain TSNAXIP1_N PF15739.5 CEG46695.1 - 2.6e-14 53.5 0.5 2.6e-14 53.5 0.5 3.2 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus KORA PF16509.5 CEG46695.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor DUF2408 PF10303.9 CEG46695.1 - 0.44 11.1 10.3 1.6 9.3 0.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) Fez1 PF06818.15 CEG46695.1 - 2.9 8.3 19.2 0.58 10.6 14.6 2.1 2 1 0 2 2 2 0 Fez1 Cnn_1N PF07989.11 CEG46695.1 - 8.5 6.6 9.4 1.4 9.1 0.3 3.7 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 zf-C3HC4 PF00097.25 CEG46696.1 - 5.7 6.9 15.3 1.5 8.8 10.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Flexi_CP_N PF08358.10 CEG46698.1 - 0.086 12.8 1.0 11 6.0 0.0 3.6 4 0 0 4 4 4 0 Carlavirus coat Lectin_leg-like PF03388.13 CEG46700.1 - 8.6e-35 120.1 0.2 1.4e-34 119.5 0.2 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CEG46700.1 - 2.9e-11 43.8 2.0 5.2e-11 42.9 2.0 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEG46700.1 - 8.4e-08 32.0 0.4 5.3e-07 29.4 0.4 2.0 1 1 0 1 1 1 1 Legume lectin domain Phage_tail_NK PF16532.5 CEG46700.1 - 0.028 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales DUF1351 PF07083.11 CEG46700.1 - 0.24 11.1 10.6 0.11 12.3 2.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) WD40 PF00400.32 CEG46701.1 - 7.1e-37 124.8 11.1 5.4e-07 30.2 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46701.1 - 5.1e-13 49.1 0.5 0.0031 17.8 0.0 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG46701.1 - 3e-07 29.5 4.6 0.041 12.5 0.0 4.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CEG46701.1 - 3.8e-07 29.8 1.5 1.9e-05 24.1 0.3 2.6 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 CEG46701.1 - 0.00015 20.8 2.9 0.59 9.0 0.2 3.1 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5570 PF17731.1 CEG46701.1 - 0.012 15.7 5.1 1.4 9.0 0.1 3.6 1 1 3 4 4 4 0 Family of unknown function (DUF5570) WD40_3 PF15911.5 CEG46701.1 - 0.012 15.6 0.1 2.5 8.2 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat PKD PF00801.20 CEG46701.1 - 0.037 13.9 1.0 25 4.8 0.0 3.4 3 1 0 3 3 3 0 PKD domain SHIPPO-rpt PF07004.12 CEG46702.1 - 0.1 13.5 1.2 0.2 12.7 1.2 1.7 1 1 0 1 1 1 0 Sperm-tail PG-rich repeat FUSC PF04632.12 CEG46705.1 - 0.092 11.3 3.5 0.16 10.4 3.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family K-box PF01486.17 CEG46705.1 - 0.27 11.4 2.1 0.42 10.8 0.5 2.0 2 0 0 2 2 2 0 K-box region Syntaxin_2 PF14523.6 CEG46705.1 - 0.51 10.7 3.2 0.25 11.7 0.2 2.0 3 0 0 3 3 3 0 Syntaxin-like protein FUSC_2 PF13515.6 CEG46705.1 - 1.9 8.6 21.1 0.034 14.3 10.5 3.1 3 1 0 3 3 3 0 Fusaric acid resistance protein-like DUF4074 PF13293.6 CEG46706.1 - 0.099 13.0 0.0 11 6.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4074) ADH_N PF08240.12 CEG46707.1 - 7.3e-17 61.2 1.0 7.5e-17 61.2 1.0 1.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Malate_synthase PF01274.22 CEG46711.1 - 9.9e-205 680.8 0.0 1.1e-204 680.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CEG46711.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family S4 PF01479.25 CEG46711.1 - 0.11 12.2 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 S4 domain Phage_integrase PF00589.22 CEG46712.1 - 0.00077 19.3 0.1 0.002 17.9 0.1 1.7 1 1 0 1 1 1 1 Phage integrase family Radical_SAM PF04055.21 CEG46712.1 - 0.044 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Radical SAM superfamily NDC10_II PF16787.5 CEG46712.1 - 0.15 11.1 0.1 0.32 10.0 0.1 1.5 1 1 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Pkinase PF00069.25 CEG46713.1 - 4.2e-11 42.7 0.0 6.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CEG46713.1 - 3e-05 23.0 0.0 4.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEG46713.1 - 0.0051 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG46713.1 - 0.0063 16.5 0.1 0.0099 15.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HicB PF05534.12 CEG46714.1 - 0.08 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 HicB family LMWPc PF01451.21 CEG46715.1 - 1.8e-12 47.9 0.0 2.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase GH43_C2 PF17851.1 CEG46716.1 - 0.055 13.2 0.5 0.51 10.0 0.4 1.9 1 1 1 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain FYVE PF01363.21 CEG46717.1 - 0.02 15.0 10.4 0.072 13.2 10.4 2.0 1 0 0 1 1 1 0 FYVE zinc finger AP_endonuc_2_N PF07582.12 CEG46717.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus FYVE_2 PF02318.16 CEG46717.1 - 1.2 9.4 11.5 11 6.3 11.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger CHAD PF05235.14 CEG46718.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 CHAD domain DUF3447 PF11929.8 CEG46720.1 - 0.024 14.6 0.1 0.089 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) CAP PF00188.26 CEG46722.1 - 1.2e-20 74.6 2.5 1.2e-20 74.6 2.5 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Hydin_ADK PF17213.3 CEG46722.1 - 0.28 11.5 4.7 0.37 11.0 4.7 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Ubie_methyltran PF01209.18 CEG46724.1 - 2.1e-15 56.7 0.0 1.1e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CEG46724.1 - 2.1e-13 50.8 0.0 5.9e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG46724.1 - 1.2e-12 48.2 0.0 2.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG46724.1 - 6.2e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG46724.1 - 6.7e-09 35.7 0.0 1.5e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG46724.1 - 4.7e-08 33.7 0.0 1.1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG46724.1 - 3.7e-05 23.3 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain E2_bind PF08825.10 CEG46724.1 - 0.075 13.2 0.9 2.2 8.5 0.4 2.8 3 0 0 3 3 3 0 E2 binding domain AdoMet_MTase PF07757.13 CEG46724.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Glyco_hydro_7 PF00840.20 CEG46724.1 - 0.2 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Peptidase_S8 PF00082.22 CEG46725.1 - 1.8e-40 139.1 5.5 7.1e-40 137.1 5.5 1.9 1 1 0 1 1 1 1 Subtilase family ATP_synth_reg PF14960.6 CEG46731.1 - 0.11 12.0 0.3 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 ATP synthase regulation Integrase_H2C2 PF17921.1 CEG46734.1 - 2.9e-11 43.3 0.2 4.6e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Mannosyl_trans3 PF11051.8 CEG46735.1 - 1.4e-29 103.4 0.0 2e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Mannosyltransferase putative Aconitase PF00330.20 CEG46736.1 - 3.1e-64 217.7 0.4 1.6e-62 212.1 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEG46736.1 - 1.6e-16 60.8 0.0 7.6e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain Aldedh PF00171.22 CEG46737.1 - 5.1e-80 269.2 0.1 5.5e-80 269.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3510 PF12022.8 CEG46738.1 - 0.013 15.9 0.6 3.8 7.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF2779 PF11074.8 CEG46738.1 - 0.072 13.6 1.8 0.1 13.1 1.3 1.6 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) CDC50 PF03381.15 CEG46740.1 - 1.5e-61 208.4 0.0 2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ENOD93 PF03386.14 CEG46741.1 - 2.9e-08 33.4 0.8 5.5e-08 32.6 0.8 1.4 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 CEG46741.1 - 0.00014 22.0 0.2 0.00035 20.7 0.2 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region FIST PF08495.10 CEG46741.1 - 0.037 14.0 0.0 0.051 13.6 0.0 1.3 1 1 0 1 1 1 0 FIST N domain Cpn60_TCP1 PF00118.24 CEG46742.1 - 2.8e-157 524.3 4.6 3.2e-157 524.1 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TraH_2 PF06871.11 CEG46742.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 TraH_2 ISN1 PF06437.11 CEG46742.1 - 0.065 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase 6PGD PF00393.19 CEG46742.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain TMEM51 PF15345.6 CEG46743.1 - 0.013 15.4 1.1 0.018 14.9 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Kei1 PF08552.11 CEG46743.1 - 0.13 12.1 1.3 0.2 11.5 1.3 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NAM-associated PF14303.6 CEG46743.1 - 0.28 11.9 10.4 1.8 9.3 10.4 2.2 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-CXXC PF02008.20 CEG46746.1 - 1.7 8.7 15.0 0.043 13.8 5.5 2.5 2 0 0 2 2 2 0 CXXC zinc finger domain FYVE_2 PF02318.16 CEG46749.1 - 0.017 15.3 5.0 0.017 15.3 5.0 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 CEG46749.1 - 0.041 14.0 13.8 0.088 13.0 13.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger MRP-S34 PF16053.5 CEG46749.1 - 0.086 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 zf-CXXC PF02008.20 CEG46749.1 - 0.29 11.2 12.5 0.032 14.3 7.2 2.1 2 0 0 2 2 2 0 CXXC zinc finger domain Neuropep_like PF15161.6 CEG46752.1 - 0.18 11.5 0.1 0.39 10.4 0.1 1.6 1 1 1 2 2 2 0 Neuropeptide-like LMWPc PF01451.21 CEG46755.1 - 3.9e-26 92.1 0.6 6.2e-25 88.2 0.6 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase REC114-like PF15165.6 CEG46756.1 - 0.041 13.7 5.2 0.05 13.4 5.2 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Microcephalin PF12258.8 CEG46756.1 - 0.11 11.7 12.1 0.14 11.4 12.1 1.1 1 0 0 1 1 1 0 Microcephalin protein Membralin PF09746.9 CEG46756.1 - 0.77 8.7 4.0 0.78 8.7 4.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.16 CEG46756.1 - 3.1 7.8 6.1 3.7 7.5 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0767 PF15990.5 CEG46756.1 - 9.7 6.4 7.3 3.8 7.7 2.7 2.2 1 1 1 2 2 2 0 UPF0767 family SPACA9 PF15120.6 CEG46757.1 - 0.062 13.1 0.8 0.077 12.8 0.1 1.6 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 SH3_3 PF08239.11 CEG46760.1 - 6.6e-07 29.5 1.0 0.073 13.4 0.1 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain Stc1 PF12898.7 CEG46760.1 - 0.00061 20.3 14.9 0.025 15.1 7.1 2.7 1 1 1 2 2 2 2 Stc1 domain Ral PF11058.8 CEG46760.1 - 0.058 13.0 1.6 0.76 9.4 0.0 3.1 3 0 0 3 3 3 0 Antirestriction protein Ral PHAT PF09246.10 CEG46760.1 - 0.1 12.4 0.0 0.58 10.0 0.0 2.2 3 0 0 3 3 3 0 PHAT Asp_Arg_Hydrox PF05118.15 CEG46764.1 - 1.5e-45 154.8 0.4 1.9e-45 154.5 0.4 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase 2OG-FeII_Oxy_5 PF13759.6 CEG46764.1 - 0.0095 16.3 0.1 0.12 12.8 0.0 2.3 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase Carbam_trans_C PF16861.5 CEG46765.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus CH PF00307.31 CEG46767.1 - 4.7e-45 152.2 4.9 1.7e-21 76.4 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CEG46767.1 - 5.1e-13 48.7 0.1 6.3e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_7 PF13499.6 CEG46767.1 - 2.4e-07 31.1 1.9 2.4e-07 31.1 1.9 2.5 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CEG46767.1 - 2.4e-06 27.3 9.0 0.0007 19.4 1.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG46767.1 - 9.9e-06 25.1 5.4 8.2e-05 22.2 0.3 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEG46767.1 - 3.1e-05 23.2 0.6 3.1e-05 23.2 0.6 2.8 2 0 0 2 2 2 1 EF hand CH_2 PF06294.11 CEG46767.1 - 0.00092 19.3 0.5 0.14 12.2 0.0 2.9 2 0 0 2 2 2 1 CH-like domain in sperm protein Spectrin PF00435.21 CEG46767.1 - 0.015 15.7 24.9 0.066 13.7 0.3 5.9 4 2 1 5 5 5 0 Spectrin repeat AATF-Che1 PF13339.6 CEG46767.1 - 0.12 13.1 7.9 0.18 12.5 0.5 3.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF2524 PF10732.9 CEG46767.1 - 0.12 12.7 10.6 0.5 10.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2524) Snapin_Pallidin PF14712.6 CEG46767.1 - 0.15 12.5 12.1 2.1 8.9 0.3 6.0 5 1 1 6 6 6 0 Snapin/Pallidin EF-hand_5 PF13202.6 CEG46767.1 - 0.21 11.1 2.7 0.2 11.2 0.3 2.3 2 0 0 2 2 2 0 EF hand NPV_P10 PF05531.12 CEG46767.1 - 1.3 9.6 13.4 38 4.8 0.1 5.9 5 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein YgaB PF14182.6 CEG46767.1 - 2.9 8.4 10.1 3.5 8.1 0.8 4.4 3 1 0 3 3 3 0 YgaB-like protein Laminin_II PF06009.12 CEG46767.1 - 7.2 6.6 16.2 0.8 9.7 2.1 4.1 4 0 0 4 4 4 0 Laminin Domain II FAP206 PF12018.8 CEG46768.1 - 9.7e-82 274.6 0.3 7.3e-81 271.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function E1-E2_ATPase PF00122.20 CEG46769.1 - 1e-51 175.0 1.2 1e-51 175.0 1.2 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEG46769.1 - 1.4e-50 171.5 0.5 1.4e-50 171.5 0.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEG46769.1 - 9.4e-23 81.6 4.8 1.1e-22 81.4 0.9 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG46769.1 - 3.3e-17 62.4 0.6 4e-16 58.9 0.1 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEG46769.1 - 1.4e-12 47.1 0.0 2.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG46769.1 - 0.0022 17.8 5.2 0.0023 17.7 1.7 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4870 PF09685.10 CEG46769.1 - 7.1 6.8 8.6 3.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4870) Sel1 PF08238.12 CEG46770.1 - 1.5e-28 98.6 20.5 7e-05 23.4 1.1 9.0 9 0 0 9 9 9 7 Sel1 repeat Nop16 PF09420.10 CEG46770.1 - 0.026 14.6 0.4 0.04 13.9 0.4 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 TPR_6 PF13174.6 CEG46770.1 - 2.9 8.7 11.8 32 5.5 0.7 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3126 PF11324.8 CEG46772.1 - 0.13 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Cyt-b5 PF00173.28 CEG46774.1 - 2.3e-07 30.9 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2543 PF10820.8 CEG46775.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) IBN_N PF03810.19 CEG46776.1 - 0.00063 19.6 0.6 0.0012 18.7 0.1 1.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF5003 PF16394.5 CEG46776.1 - 0.21 10.7 0.0 2.3 7.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5003) WD40 PF00400.32 CEG46777.1 - 1.4e-09 38.4 1.6 0.3 12.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CEG46777.1 - 0.0061 15.3 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.32 CEG46778.1 - 5.2e-18 65.1 2.7 0.00024 21.8 0.0 6.5 7 0 0 7 7 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG46778.1 - 1.1e-17 64.1 0.0 0.00038 20.7 0.0 5.9 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG46778.1 - 4.3e-05 23.0 0.1 0.044 13.1 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CEG46778.1 - 0.00013 20.8 0.0 0.2 10.3 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF2205 PF10224.9 CEG46778.1 - 0.0026 17.7 2.2 0.0071 16.3 2.2 1.7 1 0 0 1 1 1 1 Short coiled-coil protein PALB2_WD40 PF16756.5 CEG46778.1 - 0.0037 16.2 0.2 0.1 11.5 0.2 2.3 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain HALZ PF02183.18 CEG46778.1 - 0.0039 17.4 0.5 0.017 15.3 0.1 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper YabA PF06156.13 CEG46778.1 - 0.014 16.1 3.2 0.042 14.5 1.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 CEG46778.1 - 0.033 14.3 2.0 0.056 13.5 2.0 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Prp19 PF08606.11 CEG46778.1 - 0.046 13.7 0.3 0.15 12.1 0.3 1.9 1 0 0 1 1 1 0 Prp19/Pso4-like Cytochrom_D1 PF02239.16 CEG46778.1 - 0.14 10.7 0.0 0.42 9.1 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain bZIP_1 PF00170.21 CEG46778.1 - 0.16 12.1 1.2 0.92 9.7 0.3 2.3 1 1 1 2 2 2 0 bZIP transcription factor Whirly PF08536.11 CEG46779.1 - 2.4e-08 33.9 0.1 7e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Whirly transcription factor Porin_3 PF01459.22 CEG46780.1 - 7.9e-47 160.0 0.0 1e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Methyltransf_25 PF13649.6 CEG46781.1 - 4e-06 27.4 0.0 1.3e-05 25.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG46781.1 - 8.3e-06 26.4 0.0 2.7e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG46781.1 - 3.7e-05 23.6 0.0 9.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG46781.1 - 0.00035 21.2 0.0 0.00088 20.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG46781.1 - 0.00043 20.2 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CEG46781.1 - 0.034 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) SnoaL PF07366.12 CEG46782.1 - 8.5e-10 38.5 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 CEG46782.1 - 3.1e-08 34.2 0.0 5.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4995 PF16386.5 CEG46782.1 - 0.014 15.4 0.2 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF2660 PF10859.8 CEG46782.1 - 0.048 14.1 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Mito_carr PF00153.27 CEG46783.1 - 3.3e-60 200.0 4.9 3.9e-20 71.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MaoC_dehydratas PF01575.19 CEG46784.1 - 1.5e-29 102.1 0.0 2.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CEG46784.1 - 7.7e-08 32.5 0.0 0.00015 21.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ERp29_N PF07912.13 CEG46784.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain ubiquitin PF00240.23 CEG46786.1 - 0.0056 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family pP_pnuc_2 PF18166.1 CEG46786.1 - 0.051 13.6 0.4 0.18 11.8 0.3 2.0 2 1 0 2 2 2 0 Predicted pPIWI-associating nuclease DWNN PF08783.11 CEG46786.1 - 0.07 13.4 0.4 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 DWNN domain Phage_X PF05155.15 CEG46787.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage X family TYW3 PF02676.14 CEG46788.1 - 6.8e-61 205.3 0.0 1.1e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Kelch_4 PF13418.6 CEG46788.1 - 3.1e-29 100.7 13.2 8e-11 41.8 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG46788.1 - 1.3e-27 95.3 10.8 1.1e-09 38.1 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Met_10 PF02475.16 CEG46788.1 - 7e-27 94.5 0.0 1.9e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein Kelch_6 PF13964.6 CEG46788.1 - 3.5e-23 81.1 13.3 1.4e-05 25.2 0.0 7.4 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 CEG46788.1 - 1.8e-20 72.7 5.2 0.00023 21.4 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG46788.1 - 3.7e-20 71.2 10.2 9e-08 31.6 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEG46788.1 - 3.6e-13 48.9 11.2 0.0083 16.1 0.0 7.7 7 0 0 7 7 7 4 Kelch motif MTS PF05175.14 CEG46788.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEG46788.1 - 0.0097 16.6 0.0 0.06 14.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CSTF2_hinge PF14327.6 CEG46790.1 - 0.029 14.8 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Peptidase_M76 PF09768.9 CEG46791.1 - 6.3e-12 45.6 0.0 7.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CEG46791.1 - 0.018 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 SprT-like family Fimbrial_K88 PF02432.15 CEG46793.1 - 0.04 13.9 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Fimbrial, major and minor subunit HrpB_C PF08482.10 CEG46793.1 - 0.055 13.9 0.4 0.14 12.5 0.2 1.8 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal Kinesin PF00225.23 CEG46794.1 - 1.5e-118 395.5 0.1 6.4e-118 393.5 0.1 2.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG46794.1 - 4.8e-26 91.5 0.0 2.5e-25 89.1 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding Glyco_hydro_3_C PF01915.22 CEG46797.1 - 9.1e-49 166.2 0.0 1.3e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEG46797.1 - 4.4e-38 131.4 0.0 1.7e-37 129.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEG46797.1 - 0.00035 20.6 0.0 0.00094 19.2 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain RVT_2 PF07727.14 CEG46798.1 - 5.3e-58 196.5 0.0 8e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2620 PF10941.8 CEG46798.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Chitin_synth_1 PF01644.17 CEG46799.1 - 1.9e-49 167.7 0.1 3.1e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CEG46799.1 - 1.3e-24 86.8 2.9 4.8e-22 78.3 0.9 3.1 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEG46799.1 - 4.2e-09 36.6 2.8 4.2e-09 36.6 2.8 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEG46799.1 - 2.6e-08 34.0 0.0 7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 CEG46799.1 - 0.00011 22.0 0.0 0.00044 20.2 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal DivIC PF04977.15 CEG46801.1 - 2.1 8.2 11.0 0.4 10.5 6.8 2.0 2 0 0 2 2 2 0 Septum formation initiator HECT PF00632.25 CEG46802.1 - 2.4e-95 319.6 0.0 4e-95 318.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Rota_NS6 PF04866.12 CEG46803.1 - 0.094 12.9 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 UCH PF00443.29 CEG46804.1 - 1e-44 153.0 0.0 1.2e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG46804.1 - 4.6e-18 65.9 0.3 5.4e-17 62.4 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ArenaCapSnatch PF17296.2 CEG46805.1 - 0.041 13.3 0.2 0.15 11.5 0.3 1.8 2 0 0 2 2 2 0 Arenavirus cap snatching domain Mob1_phocein PF03637.17 CEG46805.1 - 0.044 13.8 0.2 0.075 13.0 0.2 1.4 1 0 0 1 1 1 0 Mob1/phocein family FH2 PF02181.23 CEG46806.1 - 6.1e-38 130.9 7.9 8.4e-38 130.4 7.9 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG46806.1 - 4.4e-07 30.5 1.5 7.2e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex ABC1 PF03109.16 CEG46807.1 - 1.6e-32 112.2 0.0 3.4e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Rotamase PF00639.21 CEG46808.1 - 3.8e-17 63.0 0.0 4.7e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CEG46808.1 - 1.4e-15 57.8 0.0 1.7e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain ATG16 PF08614.11 CEG46809.1 - 0.0012 19.2 58.2 0.011 16.0 6.6 5.5 1 1 2 4 4 4 3 Autophagy protein 16 (ATG16) HMMR_C PF15908.5 CEG46809.1 - 0.015 15.5 6.4 0.015 15.5 6.4 3.7 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 CEG46809.1 - 1.5 9.2 28.7 3.5 8.1 0.1 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) Med3 PF11593.8 CEG46809.1 - 4.7 6.3 13.6 0.09 11.9 1.8 2.7 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal LRR_6 PF13516.6 CEG46810.1 - 1.5e-12 46.5 26.8 9.2e-06 25.3 0.5 7.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 CEG46810.1 - 0.076 13.5 32.6 0.32 11.5 3.1 6.2 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) tRNA_int_endo PF01974.17 CEG46811.1 - 2.8e-18 65.7 0.3 5.5e-18 64.8 0.3 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Mrr_cat PF04471.12 CEG46811.1 - 0.064 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease Pex16 PF08610.10 CEG46812.1 - 3.4e-59 200.6 0.5 4.2e-59 200.3 0.5 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Retrotran_gag_2 PF14223.6 CEG46816.1 - 2.8e-17 62.7 0.4 4.8e-17 61.9 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG46816.1 - 0.00027 20.9 1.5 0.00054 19.9 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG46816.1 - 0.016 15.0 0.3 0.016 15.0 0.3 1.6 2 0 0 2 2 2 0 Zinc knuckle LIM_bind PF01803.16 CEG46816.1 - 0.02 14.5 1.0 0.067 12.7 1.0 1.8 1 1 0 1 1 1 0 LIM-domain binding protein zf-CCHC_5 PF14787.6 CEG46816.1 - 0.038 13.7 3.2 0.07 12.9 3.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CEG46816.1 - 0.074 13.0 0.7 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF489 PF04356.12 CEG46816.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Dopey_N PF04118.14 CEG46817.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal Peptidase_C1 PF00112.23 CEG46819.1 - 1.1e-60 205.5 8.1 2.9e-40 138.7 0.6 2.3 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 CEG46819.1 - 2.8e-15 56.5 2.3 5.8e-15 55.5 2.3 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CEG46819.1 - 1.1e-08 34.3 0.6 4.9e-05 22.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family PSI PF01437.25 CEG46819.1 - 1.6 9.3 14.7 0.14 12.7 7.2 2.7 2 0 0 2 2 2 0 Plexin repeat Cation_efflux PF01545.21 CEG46820.1 - 1.4e-46 158.7 7.0 1.8e-46 158.4 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2545 PF10810.8 CEG46820.1 - 1.7 8.8 6.7 0.54 10.4 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2545) RVT_2 PF07727.14 CEG46822.1 - 2e-30 106.2 0.2 2.9e-30 105.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 CEG46825.1 - 1.5e-56 192.5 0.1 1.8e-56 192.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEG46825.1 - 0.00063 19.1 0.0 0.0016 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 CEG46825.1 - 0.00085 18.3 1.0 0.0069 15.3 1.0 2.1 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CEG46825.1 - 0.0044 16.2 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEG46825.1 - 0.099 11.8 0.1 0.21 10.8 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEG46825.1 - 0.17 10.9 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein BAH PF01426.18 CEG46829.1 - 1.9e-14 53.6 0.8 4.1e-14 52.5 0.8 1.5 1 0 0 1 1 1 1 BAH domain ELM2 PF01448.24 CEG46829.1 - 0.0046 17.7 0.0 0.013 16.3 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain Peptidase_S9 PF00326.21 CEG46830.1 - 1.4e-65 220.7 0.0 4.9e-65 219.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CEG46830.1 - 1.9e-32 112.6 1.0 2.7e-32 112.1 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF2066 PF09839.9 CEG46831.1 - 0.17 11.2 0.0 0.2 11.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) zf-HC5HC2H_2 PF13832.6 CEG46833.1 - 4.2e-40 136.3 75.5 2e-18 66.5 7.6 8.0 8 1 1 9 9 9 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEG46833.1 - 4.7e-23 81.2 35.9 3.3e-14 52.9 1.9 8.7 8 2 1 9 9 9 3 PHD-like zinc-binding domain PHD_2 PF13831.6 CEG46833.1 - 7.5e-18 63.8 16.9 1e-13 50.6 1.3 7.1 8 0 0 8 8 8 3 PHD-finger PHD PF00628.29 CEG46833.1 - 5.7e-12 45.3 28.1 4.7e-08 32.8 5.0 10.4 11 0 0 11 11 11 6 PHD-finger C1_1 PF00130.22 CEG46833.1 - 0.016 15.1 1.1 0.016 15.1 1.1 10.2 11 3 2 13 13 13 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNARE PF05739.19 CEG46834.1 - 2.9e-10 40.0 3.8 1.3e-09 37.9 3.8 2.1 1 1 0 1 1 1 1 SNARE domain eIF3g PF12353.8 CEG46834.1 - 0.064 13.6 0.1 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Cellulase PF00150.18 CEG46837.1 - 6.4e-42 143.9 0.4 7.3e-42 143.7 0.4 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mannitol_dh PF01232.23 CEG46838.1 - 0.032 14.4 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain DUF1400 PF07176.11 CEG46838.1 - 0.067 13.5 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PhoLip_ATPase_C PF16212.5 CEG46840.1 - 7e-62 209.4 30.9 7e-62 209.4 30.9 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG46840.1 - 8.8e-14 51.0 2.2 8.8e-14 51.0 2.2 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEG46840.1 - 1.8e-12 47.1 0.0 3.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG46840.1 - 4.5e-10 40.2 0.2 0.0011 19.3 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG46840.1 - 2e-05 24.2 0.0 7.9e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG46840.1 - 0.0021 17.9 0.0 0.0058 16.4 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rubredoxin PF00301.20 CEG46840.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin Anoctamin PF04547.12 CEG46841.1 - 6.5e-09 35.1 11.8 4.6e-08 32.3 3.2 2.7 3 0 0 3 3 3 2 Calcium-activated chloride channel PHM7_cyt PF14703.6 CEG46841.1 - 3.5e-08 33.9 0.0 7.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 CEG46841.1 - 0.052 12.8 9.0 0.1 11.9 4.5 2.8 2 1 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate DNA_ligase_C PF17879.1 CEG46841.1 - 0.055 13.5 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA ligase C-terminal domain Cadherin_C_2 PF16492.5 CEG46841.1 - 0.071 13.9 0.1 0.071 13.9 0.1 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal RSN1_TM PF13967.6 CEG46841.1 - 1.8 8.3 5.1 1.1 8.9 0.1 2.9 4 0 0 4 4 4 0 Late exocytosis, associated with Golgi transport Uma2 PF05685.12 CEG46846.1 - 7.7e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 Putative restriction endonuclease AA_permease_2 PF13520.6 CEG46849.1 - 2e-53 181.7 51.5 2.8e-53 181.3 51.5 1.1 1 0 0 1 1 1 1 Amino acid permease IF-2B PF01008.17 CEG46852.1 - 0.016 14.5 0.5 0.027 13.7 0.5 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family Unstab_antitox PF09720.10 CEG46852.1 - 3.6 7.7 6.7 0.53 10.4 0.2 3.0 4 0 0 4 4 4 0 Putative addiction module component GTP_EFTU PF00009.27 CEG46853.1 - 1.8e-49 167.9 0.0 3.1e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CEG46853.1 - 8.6e-41 138.4 0.3 1.7e-40 137.5 0.3 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU_D2 PF03144.25 CEG46853.1 - 3.5e-07 30.5 0.1 8.1e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEG46853.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_C PF00679.24 CEG46853.1 - 0.00012 22.1 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Mg_trans_NIPA PF05653.14 CEG46858.1 - 2.7e-14 53.0 3.8 2.7e-14 53.0 3.8 1.5 1 1 1 2 2 2 1 Magnesium transporter NIPA DUF2499 PF10693.9 CEG46858.1 - 0.019 15.2 0.1 0.15 12.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2499) GST_C_3 PF14497.6 CEG46860.1 - 2.9e-19 69.1 0.0 4.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEG46860.1 - 7.8e-10 39.0 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEG46860.1 - 2.4e-07 30.9 0.0 4.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEG46860.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEG46860.1 - 0.0027 18.0 0.0 0.005 17.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEG46860.1 - 0.0081 16.2 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CEG46860.1 - 0.0091 15.8 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YabA PF06156.13 CEG46861.1 - 0.012 16.2 3.9 0.012 16.2 3.9 4.5 1 1 2 4 4 4 0 Initiation control protein YabA CCDC-167 PF15188.6 CEG46861.1 - 0.025 14.9 2.9 0.025 14.9 2.9 4.5 2 2 2 4 4 4 0 Coiled-coil domain-containing protein 167 VASP_tetra PF08776.11 CEG46861.1 - 0.029 14.0 1.2 0.029 14.0 1.2 3.1 2 1 0 2 2 2 0 VASP tetramerisation domain DUF4140 PF13600.6 CEG46861.1 - 0.52 10.8 26.4 0.95 9.9 1.0 4.5 4 1 1 5 5 5 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CEG46861.1 - 1.4 9.4 15.2 30 5.1 0.1 5.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 CEG46861.1 - 2.2 8.4 22.3 4.4 7.5 0.3 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 CEG46861.1 - 2.5 8.3 33.4 0.29 11.3 4.6 4.5 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4614 PF15391.6 CEG46862.1 - 0.067 13.2 1.0 0.069 13.1 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) AMP-binding PF00501.28 CEG46863.1 - 7.8e-33 113.7 0.1 1.4e-32 112.8 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme MatE PF01554.18 CEG46864.1 - 7.4e-38 129.7 29.8 1.5e-21 76.7 11.7 3.5 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 CEG46864.1 - 7.1e-05 22.9 14.2 7.1e-05 22.9 14.2 3.9 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain PH PF00169.29 CEG46865.1 - 8e-69 228.8 2.9 3.8e-11 43.4 0.0 6.8 6 1 0 6 6 6 6 PH domain PH_8 PF15409.6 CEG46865.1 - 4.5e-23 81.3 0.7 7.7e-05 22.9 0.0 6.6 6 0 0 6 6 6 6 Pleckstrin homology domain PH_11 PF15413.6 CEG46865.1 - 3.7e-16 59.4 21.3 0.037 14.5 0.3 8.5 7 3 1 8 8 8 6 Pleckstrin homology domain Retrotran_gag_3 PF14244.6 CEG46865.1 - 0.18 11.6 6.3 1.6 8.6 0.3 2.9 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type GCOM2 PF15328.6 CEG46865.1 - 0.47 10.8 3.3 1.1 9.6 3.3 1.5 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF4219 PF13961.6 CEG46865.1 - 4.3 7.1 5.5 12 5.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Rap_GAP PF02145.15 CEG46867.1 - 8.1e-55 185.3 0.0 1.6e-54 184.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RGS PF00615.19 CEG46867.1 - 0.0028 17.9 0.0 0.0084 16.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ank_2 PF12796.7 CEG46869.1 - 6.1e-29 100.5 6.3 2.1e-08 34.6 0.0 5.0 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG46869.1 - 3.2e-23 79.3 1.0 0.0001 22.4 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CEG46869.1 - 1.1e-22 79.8 2.9 1.6e-06 28.2 0.5 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG46869.1 - 5.4e-19 68.3 1.0 3.6e-05 24.2 0.1 6.3 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG46869.1 - 2.4e-16 59.3 4.7 0.0013 19.1 0.0 6.5 6 1 0 6 6 6 3 Ankyrin repeat LPAM_1 PF08139.12 CEG46869.1 - 0.069 13.7 0.5 0.26 11.8 0.5 2.1 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site EF-hand_6 PF13405.6 CEG46870.1 - 9.9e-07 28.2 3.9 0.00038 20.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CEG46870.1 - 2e-06 27.0 0.4 0.006 16.0 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG46870.1 - 4.3e-05 23.9 6.0 0.093 13.2 0.0 4.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEG46870.1 - 0.00018 21.3 0.4 0.098 12.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG46870.1 - 0.037 13.5 0.4 0.29 10.7 0.0 2.6 3 0 0 3 3 3 0 EF hand zf-NOSIP PF15906.5 CEG46874.1 - 3.2e-11 43.2 0.2 6.5e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 CEG46874.1 - 0.016 15.5 2.3 0.58 10.5 0.5 2.4 2 0 0 2 2 2 0 Ring finger domain Activator-TraM PF11657.8 CEG46874.1 - 0.027 14.3 3.3 0.044 13.6 3.3 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM zinc_ribbon_13 PF09855.9 CEG46874.1 - 0.054 13.7 0.2 1.6 8.9 0.3 2.5 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RING_UBOX PF13445.6 CEG46874.1 - 0.069 13.2 1.1 0.069 13.2 1.1 1.9 2 0 0 2 2 2 0 RING-type zinc-finger DUF2093 PF09866.9 CEG46874.1 - 0.34 10.4 2.4 2.9 7.4 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2093) CLN3 PF02487.17 CEG46875.1 - 2.9e-76 257.1 17.5 4.9e-76 256.3 17.5 1.3 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CEG46875.1 - 0.00015 20.8 34.9 0.0002 20.4 34.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-trcl PF13451.6 CEG46875.1 - 0.27 11.2 0.0 0.51 10.3 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain GDI PF00996.18 CEG46877.1 - 1.9e-59 201.4 0.0 8.1e-23 80.6 0.0 3.1 2 1 0 3 3 3 3 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 CEG46877.1 - 0.21 11.2 1.2 0.47 10.0 0.5 2.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Tissue_fac PF01108.17 CEG46878.1 - 0.33 10.8 4.0 0.51 10.2 0.3 2.9 3 0 0 3 3 3 0 Tissue factor FAA_hydro_N_2 PF18288.1 CEG46878.1 - 2.8 8.4 7.2 14 6.2 0.1 4.2 1 1 3 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 DUF89 PF01937.19 CEG46881.1 - 2.2e-63 214.4 0.0 2.6e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pox_MCEL PF03291.16 CEG46882.1 - 1.2e-52 179.1 0.0 3.1e-52 177.7 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme WW PF00397.26 CEG46882.1 - 4.5e-11 42.6 2.7 3.2e-05 23.9 0.6 2.5 2 0 0 2 2 2 2 WW domain Methyltransf_25 PF13649.6 CEG46882.1 - 5.1e-09 36.7 0.2 1.1e-06 29.3 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG46882.1 - 3.9e-06 27.5 0.0 1.2e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG46882.1 - 2.1e-05 24.3 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG46882.1 - 3e-05 24.6 0.3 0.0016 19.0 0.3 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG46882.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCRF PF03462.18 CEG46882.1 - 0.011 15.7 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 PCRF domain CMAS PF02353.20 CEG46882.1 - 0.12 11.6 0.2 16 4.6 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase IBN_N PF03810.19 CEG46883.1 - 4.3e-09 36.2 0.7 1.7e-08 34.3 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_C PF08767.11 CEG46883.1 - 0.0084 15.3 5.2 0.01 15.0 2.5 2.4 2 1 0 2 2 2 1 CRM1 C terminal DUF1759 PF03564.15 CEG46883.1 - 0.013 15.4 0.0 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DCB PF16213.5 CEG46883.1 - 0.12 12.0 0.1 2.3 7.8 0.4 2.8 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 LEM PF03020.15 CEG46884.1 - 0.029 13.9 0.9 1.1 8.9 0.0 2.9 2 1 1 3 3 3 0 LEM domain DUF1402 PF07182.11 CEG46884.1 - 0.054 12.6 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) Ras_bdg_2 PF14847.6 CEG46884.1 - 0.099 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PAH PF02671.21 CEG46885.1 - 1.8e-41 140.0 11.1 1.1e-17 63.8 3.0 4.3 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CEG46885.1 - 5.1e-38 129.1 1.6 6e-38 128.9 0.0 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Sin3a_C PF16879.5 CEG46885.1 - 1.1e-37 130.3 0.5 1.1e-37 130.3 0.5 3.5 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein CDC24_OB1 PF17246.2 CEG46885.1 - 0.049 13.8 0.7 0.41 10.8 0.1 2.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 CHASE3 PF05227.13 CEG46885.1 - 0.12 12.3 5.8 0.038 13.9 1.6 2.4 2 0 0 2 2 2 0 CHASE3 domain Zn_protease PF05618.11 CEG46885.1 - 0.12 12.3 0.4 0.3 11.0 0.2 1.8 2 0 0 2 2 2 0 Putative ATP-dependant zinc protease DUF1722 PF08349.11 CEG46885.1 - 0.17 12.1 7.7 6.1 7.2 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1722) Rotamase PF00639.21 CEG46885.1 - 1.7 9.7 6.3 31 5.6 0.3 3.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain DnaJ_C PF01556.18 CEG46890.1 - 8.7e-42 142.7 0.3 1.2e-41 142.3 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG46890.1 - 1.1e-22 79.9 0.1 2.2e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEG46890.1 - 2.3e-15 56.7 19.1 4.4e-15 55.8 19.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEG46890.1 - 0.015 15.3 9.9 0.27 11.2 1.1 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEG46890.1 - 0.056 13.5 7.4 2 8.5 0.3 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CEG46890.1 - 0.28 11.2 7.6 2.2 8.4 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CEG46890.1 - 5.1 7.2 9.0 30 4.7 9.0 2.1 1 1 0 1 1 1 0 zinc-ribbons Ribosomal_L31e PF01198.19 CEG46891.1 - 3.7e-42 142.5 2.6 5.2e-42 142.0 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 CEG46891.1 - 0.0069 16.2 0.1 0.24 11.3 0.0 2.2 1 1 1 2 2 2 2 DNA mismatch endonuclease Vsr Acyl-CoA_dh_1 PF00441.24 CEG46892.1 - 2.9e-29 102.2 0.1 5.5e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG46892.1 - 3.4e-28 98.5 0.0 7.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEG46892.1 - 2.8e-21 75.5 0.0 4.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG46892.1 - 3e-08 34.0 0.0 6.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain hnRNP_Q_AcD PF18360.1 CEG46893.1 - 1.9e-24 85.4 0.1 2.6e-10 40.1 0.0 3.6 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain RXLR PF16810.5 CEG46894.1 - 0.053 14.0 0.6 0.11 12.9 0.5 1.6 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity HU-CCDC81_euk_2 PF18289.1 CEG46895.1 - 0.075 13.2 0.8 0.12 12.5 0.8 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Elong_Iki1 PF10483.9 CEG46898.1 - 2.7e-11 43.5 7.0 1e-10 41.6 7.0 1.8 1 1 0 1 1 1 1 Elongator subunit Iki1 ELP6 PF09807.9 CEG46898.1 - 0.00031 20.2 0.1 0.00053 19.5 0.1 1.4 1 0 0 1 1 1 1 Elongation complex protein 6 DUF835 PF05763.12 CEG46898.1 - 0.00042 20.1 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF835) Acyl-ACP_TE PF01643.17 CEG46898.1 - 0.019 14.2 1.4 0.02 14.2 0.4 1.5 2 0 0 2 2 2 0 Acyl-ACP thioesterase TPR_2 PF07719.17 CEG46899.1 - 5.4e-05 23.0 8.4 0.011 15.8 0.4 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEG46899.1 - 6.4e-05 22.6 9.2 0.0014 18.3 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG46899.1 - 0.00038 20.1 0.1 0.058 13.1 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 CEG46899.1 - 0.00062 19.8 5.1 0.58 10.5 0.3 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG46899.1 - 0.00065 20.3 0.4 1.3 9.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CEG46899.1 - 0.003 17.6 0.3 0.0086 16.1 0.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 CEG46899.1 - 0.0076 16.2 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG46899.1 - 0.11 12.7 0.2 0.54 10.4 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG46899.1 - 0.16 12.1 0.6 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Ribosomal_S25 PF03297.15 CEG46900.1 - 6.7e-40 135.4 5.6 7.5e-40 135.2 5.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein PPP1R35_C PF15503.6 CEG46900.1 - 0.016 15.0 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Rrf2 PF02082.20 CEG46900.1 - 0.062 13.7 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator DDRGK PF09756.9 CEG46900.1 - 0.071 12.7 2.6 0.13 11.8 2.6 1.4 1 1 0 1 1 1 0 DDRGK domain HTH_DeoR PF08220.12 CEG46900.1 - 0.074 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain zf-DNA_Pol PF08996.10 CEG46900.1 - 0.16 11.7 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger HA2 PF04408.23 CEG46901.1 - 6e-22 78.0 0.2 2.2e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG46901.1 - 1.8e-15 57.0 0.0 7.6e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG46901.1 - 5.1e-11 42.9 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG46901.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG46901.1 - 0.00011 22.5 0.0 0.00039 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEG46901.1 - 0.0075 15.4 0.0 0.023 13.7 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CEG46901.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEG46901.1 - 0.03 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CEG46901.1 - 0.037 13.4 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CEG46901.1 - 0.04 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEG46901.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG46901.1 - 0.28 11.7 0.4 0.64 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PX PF00787.24 CEG46902.1 - 5.9e-11 42.4 1.8 3.1e-10 40.0 0.4 2.4 2 1 0 2 2 2 1 PX domain Pkinase PF00069.25 CEG46903.1 - 9e-69 231.8 0.0 1.8e-68 230.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CEG46903.1 - 1.5e-37 127.5 0.0 5.4e-18 64.8 0.1 3.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CEG46903.1 - 1.7e-33 116.0 0.0 3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG46903.1 - 1.8e-06 27.5 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG46903.1 - 0.0057 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.24 CEG46906.1 - 3e-10 40.1 2.8 1.8e-09 37.6 2.8 2.2 1 1 0 1 1 1 1 PX domain SR-25 PF10500.9 CEG46906.1 - 3 7.4 13.5 2.7 7.5 5.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cep3 PF16846.5 CEG46907.1 - 0.12 10.8 0.2 0.12 10.8 0.2 1.0 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Myosin_head PF00063.21 CEG46908.1 - 2e-210 700.5 8.3 4e-210 699.5 8.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEG46908.1 - 0.00018 21.0 31.9 0.34 10.8 0.1 5.8 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CEG46908.1 - 0.01 16.1 0.6 0.75 10.1 0.0 3.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG46908.1 - 0.025 15.0 0.0 0.025 15.0 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain Barttin PF15462.6 CEG46908.1 - 0.033 14.0 7.7 0.081 12.7 1.6 2.8 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Myosin_N PF02736.19 CEG46908.1 - 0.12 12.2 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ATP_bind_1 PF03029.17 CEG46908.1 - 0.48 10.2 4.1 22 4.7 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FAD_SOX PF18371.1 CEG46908.1 - 1.5 9.2 5.4 1.6 9.1 1.4 3.1 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase YabA PF06156.13 CEG46908.1 - 6.9 7.4 25.5 0.25 12.0 2.0 4.5 2 1 2 4 4 4 0 Initiation control protein YabA betaPIX_CC PF16523.5 CEG46908.1 - 7.3 6.5 17.8 0.36 10.7 3.8 3.6 3 0 0 3 3 3 0 betaPIX coiled coil Cystatin PF00031.21 CEG46909.1 - 5.4e-05 23.4 0.0 6.2e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CEG46909.1 - 0.0001 22.6 0.0 0.00012 22.3 0.0 1.1 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor Glyco_hydro81C PF17652.1 CEG46910.1 - 5.3e-114 381.1 3.7 5.7e-114 381.0 2.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG46910.1 - 2.5e-49 168.2 0.1 3.4e-49 167.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Tn7_TnsC_Int PF11426.8 CEG46910.1 - 0.029 14.5 0.2 0.066 13.4 0.2 1.5 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC DUF3618 PF12277.8 CEG46911.1 - 0.041 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DAHP_snth_FXD PF18152.1 CEG46911.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain DUF883 PF05957.13 CEG46911.1 - 0.13 12.9 3.3 14 6.4 0.0 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) I_LWEQ PF01608.17 CEG46911.1 - 0.18 12.0 2.2 0.32 11.2 2.2 1.5 1 1 0 1 1 1 0 I/LWEQ domain DUF5446 PF17522.2 CEG46912.1 - 0.053 13.7 0.4 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Kinesin PF00225.23 CEG46916.1 - 5.9e-93 311.4 0.9 5.9e-93 311.4 0.9 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG46916.1 - 2.3e-36 125.0 0.0 6.6e-36 123.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Leu_zip PF15294.6 CEG46916.1 - 0.086 12.3 16.9 0.06 12.8 0.4 2.7 2 0 0 2 2 2 0 Leucine zipper CENP-F_leu_zip PF10473.9 CEG46916.1 - 1.9 8.5 21.4 4.5 7.3 0.6 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 CEG46916.1 - 3 8.3 20.8 0.24 11.8 2.1 4.1 3 1 0 3 3 3 0 Csm1 N-terminal domain SKIP_SNW PF02731.15 CEG46916.1 - 4.9 6.8 8.4 0.43 10.2 1.8 2.7 3 0 0 3 3 3 0 SKIP/SNW domain DUF87 PF01935.17 CEG46916.1 - 8.3 6.4 10.1 29 4.7 0.0 3.7 3 1 0 3 3 3 0 Helicase HerA, central domain KxDL PF10241.9 CEG46916.1 - 9.8 6.5 11.1 13 6.1 0.8 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein PH PF00169.29 CEG46918.1 - 6.8e-18 65.1 0.0 1.5e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 PH domain RGS PF00615.19 CEG46918.1 - 0.00016 21.9 2.5 0.00016 21.9 0.4 2.2 2 1 0 2 2 2 1 Regulator of G protein signaling domain PH_11 PF15413.6 CEG46918.1 - 0.00075 19.9 0.9 0.062 13.7 0.9 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 CEG46918.1 - 0.0042 17.2 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF4464 PF14713.6 CEG46919.1 - 3.2e-94 314.7 1.1 3.6e-94 314.5 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Phage_tail_APC PF16778.5 CEG46919.1 - 0.14 12.0 0.2 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein NPP1 PF05630.11 CEG46922.1 - 5.3e-48 163.7 0.0 6.3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) peroxidase PF00141.23 CEG46923.1 - 0.0016 18.2 0.0 0.0025 17.5 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Phytochelatin PF05023.14 CEG46925.1 - 2.3e-86 288.4 0.0 3.7e-86 287.7 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 CEG46925.1 - 0.0067 17.0 0.1 0.96 10.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase_C39 like family Gcd10p PF04189.13 CEG46927.1 - 1.2e-65 221.6 0.0 1.7e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family Metallophos_C PF14008.6 CEG46928.1 - 1.1e-16 61.4 0.1 3.2e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CEG46928.1 - 5.5e-15 55.7 0.0 1.9e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 CEG46928.1 - 1.8e-14 54.7 1.1 3.5e-14 53.8 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.29 CEG46929.1 - 9.7e-44 149.0 0.0 1.8e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CEG46929.1 - 1.2e-30 106.8 0.0 2.6e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CEG46929.1 - 6.1e-12 45.1 1.7 7.6e-12 44.8 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CEG46929.1 - 5.6e-06 26.8 0.2 0.001 19.5 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEG46929.1 - 2.4e-05 24.1 0.0 5.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG46929.1 - 2.5e-05 24.3 0.0 0.0001 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG46929.1 - 0.00018 21.8 0.3 0.055 13.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CEG46929.1 - 0.00019 20.7 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CEG46929.1 - 0.004 17.7 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEG46929.1 - 0.0043 16.8 0.2 0.01 15.6 0.1 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 CEG46929.1 - 0.0071 16.6 0.1 0.018 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CEG46929.1 - 0.012 15.8 0.1 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CEG46929.1 - 0.014 14.7 0.3 0.036 13.4 0.3 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CEG46929.1 - 0.038 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEG46929.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEG46929.1 - 0.058 12.7 0.2 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 CEG46929.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEG46929.1 - 0.066 12.9 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 CEG46929.1 - 0.076 12.9 0.6 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 CEG46929.1 - 0.11 12.6 0.0 0.44 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CEG46929.1 - 0.12 11.9 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CEG46929.1 - 0.17 11.0 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CEG46929.1 - 0.18 11.3 0.2 0.75 9.3 0.2 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CEG46929.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_hydro_6 PF01341.17 CEG46932.1 - 2.4e-46 158.9 0.0 3.2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 CEG46934.1 - 2.4e-51 175.3 1.0 3.3e-51 174.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 CEG46935.1 - 4.4e-47 161.3 0.3 6.5e-47 160.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF998 PF06197.13 CEG46935.1 - 0.11 12.0 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Glyco_hydro_6 PF01341.17 CEG46937.1 - 1.3e-49 169.6 0.0 1.8e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF1611 PF07755.11 CEG46937.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain RVT_2 PF07727.14 CEG46940.1 - 1.6e-16 60.7 2.0 3.6e-08 33.4 0.6 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEG46940.1 - 2.2e-09 37.5 0.0 6.9e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CEG46940.1 - 0.012 15.3 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain PX PF00787.24 CEG46941.1 - 1.4e-06 28.2 0.1 5.6e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 PX domain NUDIX PF00293.28 CEG46942.1 - 0.00053 20.0 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain Aminotran_MocR PF12897.7 CEG46942.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MRP-L46 PF11788.8 CEG46942.1 - 0.4 11.4 0.0 0.4 11.4 0.0 4.5 3 2 1 5 5 5 0 39S mitochondrial ribosomal protein L46 SCAB-Ig PF16709.5 CEG46946.1 - 2.1e-06 27.7 0.0 6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein TMF_TATA_bd PF12325.8 CEG46946.1 - 0.0073 16.5 1.5 0.02 15.1 1.5 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding TRAF_BIRC3_bd PF16673.5 CEG46946.1 - 0.01 15.6 1.1 0.033 14.0 1.1 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain XhlA PF10779.9 CEG46946.1 - 0.15 12.2 1.3 0.33 11.2 1.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA YtxH PF12732.7 CEG46947.1 - 0.019 15.5 0.6 0.18 12.4 0.4 2.2 2 1 0 2 2 2 0 YtxH-like protein CLZ PF16526.5 CEG46947.1 - 0.053 13.9 0.6 0.098 13.0 0.6 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4574 PF15141.6 CEG46947.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 KASH_CCD PF14662.6 CEG46948.1 - 0.00054 19.9 4.5 0.00078 19.3 4.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SKA2 PF16740.5 CEG46948.1 - 0.0041 16.9 3.6 0.0072 16.1 3.6 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 UPF0449 PF15136.6 CEG46948.1 - 0.029 14.9 0.8 0.042 14.3 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF501 PF04417.12 CEG46948.1 - 0.031 14.1 0.2 0.048 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Lectin_N PF03954.14 CEG46948.1 - 0.039 13.7 2.9 0.097 12.4 2.9 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Sec34 PF04136.15 CEG46948.1 - 0.055 13.3 3.4 0.13 12.2 3.4 1.6 1 0 0 1 1 1 0 Sec34-like family RdRP_5 PF07925.11 CEG46948.1 - 0.067 10.6 0.1 0.07 10.5 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 PikAIV_N PF18605.1 CEG46948.1 - 0.067 12.8 0.5 0.15 11.7 0.5 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PBP PF01161.20 CEG46948.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Dis3l2_C_term PF17877.1 CEG46948.1 - 0.075 13.4 0.6 0.51 10.7 0.1 2.4 1 1 1 2 2 2 0 DIS3-like exonuclease 2 C terminal LMBR1 PF04791.16 CEG46948.1 - 0.13 11.1 0.4 0.14 11.0 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 CEG46948.1 - 0.25 10.6 5.4 0.36 10.1 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 CEG46949.1 - 0.039 14.6 0.3 0.039 14.6 0.3 7.4 3 1 4 7 7 7 0 SlyX Ribosomal_L31e PF01198.19 CEG46949.1 - 5 7.4 8.8 17 5.7 1.6 2.8 3 0 0 3 3 3 0 Ribosomal protein L31e Pellino PF04710.14 CEG46950.1 - 1.2e-48 165.8 3.0 4.5e-26 91.5 0.2 4.5 3 2 1 5 5 5 3 Pellino zf-RING_2 PF13639.6 CEG46950.1 - 0.0025 18.1 6.7 0.071 13.4 0.4 3.0 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 CEG46950.1 - 0.027 14.4 4.8 0.47 10.4 0.1 2.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 CEG46950.1 - 0.043 14.1 0.3 0.043 14.1 0.3 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEG46950.1 - 0.12 12.3 8.3 0.65 9.9 0.4 3.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEG46950.1 - 0.24 11.5 6.2 2.5 8.2 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CEG46950.1 - 2.7 7.9 12.5 0.47 10.4 0.1 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 CEG46950.1 - 4 7.1 4.9 6.2 6.5 0.1 3.1 3 0 0 3 3 3 0 RecR protein Ion_trans PF00520.31 CEG46951.1 - 1.4e-42 145.6 30.6 1.5e-22 80.1 8.5 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 CEG46951.1 - 1.7e-19 69.5 18.8 1.6e-09 37.6 6.8 3.5 3 0 0 3 3 3 2 Ion channel TetR_C_3 PF08362.11 CEG46951.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region IRK PF01007.20 CEG46951.1 - 0.45 10.3 4.2 0.29 10.9 1.2 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Cupin_8 PF13621.6 CEG46953.1 - 6.7e-21 75.1 0.5 2.9e-13 50.1 0.0 2.6 2 1 0 2 2 2 2 Cupin-like domain JmjC PF02373.22 CEG46953.1 - 4.2e-13 49.7 0.1 1.1e-12 48.4 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CEG46953.1 - 0.058 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Vesiculo_matrix PF06326.12 CEG46953.1 - 0.071 12.9 0.2 14 5.4 0.0 3.0 3 0 0 3 3 3 0 Vesiculovirus matrix protein Leader_Trp PF08255.11 CEG46953.1 - 1.8 8.8 4.5 0.69 10.0 0.7 2.5 2 0 0 2 2 2 0 Trp-operon Leader Peptide YAF2_RYBP PF17219.3 CEG46953.1 - 6.2 6.5 5.9 24 4.6 0.2 3.2 3 0 0 3 3 3 0 Yaf2/RYBP C-terminal binding motif GFA PF04828.14 CEG46954.1 - 0.00026 21.3 0.7 0.00057 20.2 0.7 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.6 CEG46954.1 - 0.0041 16.9 3.8 0.011 15.6 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG46954.1 - 0.0047 16.8 3.0 0.011 15.6 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phenol_monoox PF04663.12 CEG46954.1 - 0.0056 16.8 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 Phenol hydroxylase conserved region zf-RING_5 PF14634.6 CEG46954.1 - 0.022 14.7 4.9 0.049 13.6 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG46954.1 - 0.086 12.9 1.3 0.38 10.8 1.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CEG46954.1 - 0.14 12.5 3.1 0.41 11.0 3.1 1.8 1 0 0 1 1 1 0 Ring finger domain DUF2304 PF10066.9 CEG46954.1 - 2.7 8.2 9.1 0.49 10.6 1.4 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) DnaJ PF00226.31 CEG46955.1 - 4.2e-20 71.6 0.7 8e-20 70.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain HIP1_clath_bdg PF16515.5 CEG46956.1 - 0.002 18.7 3.1 0.002 18.7 3.1 5.3 2 1 4 6 6 6 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CEG46956.1 - 0.0032 18.0 9.7 0.0032 18.0 9.7 2.7 1 1 1 2 2 2 1 Fez1 DUF2087 PF09860.9 CEG46956.1 - 0.0094 16.1 1.9 1 9.5 0.5 3.6 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2087) PKcGMP_CC PF16808.5 CEG46956.1 - 0.012 15.4 0.5 0.012 15.4 0.5 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF812 PF05667.11 CEG46956.1 - 0.073 12.0 28.6 0.081 11.8 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF390 PF04094.14 CEG46956.1 - 8.5 4.5 11.5 11 4.2 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Pkinase PF00069.25 CEG46957.1 - 2.1e-53 181.4 0.0 4.9e-53 180.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46957.1 - 9.2e-53 179.2 0.0 1.2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG46957.1 - 0.0091 14.8 1.2 0.0098 14.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG46957.1 - 0.017 14.1 0.0 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CEG46957.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG46957.1 - 0.29 11.0 2.6 0.33 10.8 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 CEG46958.1 - 1.1e-40 139.6 0.5 4.2e-39 134.4 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 CEG46958.1 - 9.2e-13 48.6 0.1 1.8e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG46958.1 - 0.002 18.5 2.6 0.021 15.2 2.6 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain HCV_capsid PF01543.17 CEG46958.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus capsid protein YWFCY PF14293.6 CEG46963.1 - 0.13 12.6 0.2 0.21 11.9 0.2 1.3 1 0 0 1 1 1 0 YWFCY protein BAG6 PF12057.8 CEG46964.1 - 0.17 11.6 1.9 0.24 11.1 0.7 1.9 1 1 1 2 2 2 0 BCL2-associated athanogene 6 Selenoprotein_S PF06936.11 CEG46965.1 - 0.021 14.7 0.3 0.021 14.7 0.3 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ins_P5_2-kin PF06090.12 CEG46966.1 - 6.1e-93 311.9 5.9 8.7e-93 311.4 5.9 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF1981 PF09324.10 CEG46966.1 - 0.089 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) CLTH PF10607.9 CEG46967.1 - 1.3e-21 77.0 1.8 1.5e-21 76.8 0.0 2.0 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CEG46967.1 - 6.3e-09 35.7 6.0 2e-08 34.1 6.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG46967.1 - 4.6e-07 29.7 8.0 4.8e-07 29.6 6.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEG46967.1 - 5.4e-06 26.5 3.8 2.1e-05 24.6 3.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG46967.1 - 2.4e-05 24.1 4.9 8.3e-05 22.4 4.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG46967.1 - 4.4e-05 23.7 6.8 0.00018 21.8 6.8 2.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CEG46967.1 - 0.00017 21.4 5.8 0.00068 19.4 5.8 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG46967.1 - 0.0002 21.1 7.4 0.00069 19.4 7.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phospholip_A2_3 PF09056.11 CEG46967.1 - 0.0023 18.5 0.1 0.0062 17.1 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 zf-C3HC4_2 PF13923.6 CEG46967.1 - 0.0031 17.3 6.5 0.009 15.8 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HATPase_c_3 PF13589.6 CEG46967.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BMC PF00936.19 CEG46967.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 BMC domain zf-RING_4 PF14570.6 CEG46967.1 - 0.14 12.0 3.9 0.39 10.5 3.9 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CEG46967.1 - 7.4 7.0 8.7 1.7 9.0 4.8 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain SlyX PF04102.12 CEG46968.1 - 0.0037 17.9 1.3 0.0074 16.9 1.3 1.6 1 0 0 1 1 1 1 SlyX Fib_alpha PF08702.10 CEG46968.1 - 0.013 15.7 2.9 0.024 14.8 2.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 CEG46968.1 - 0.02 13.4 2.7 0.022 13.3 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1664 PF07889.12 CEG46968.1 - 0.11 12.5 0.9 0.18 11.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 CEG46968.1 - 0.12 11.9 3.0 0.15 11.7 3.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-RING_2 PF13639.6 CEG46970.1 - 1e-11 45.0 7.3 2.5e-11 43.7 7.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG46970.1 - 2e-07 31.2 7.4 4.7e-07 30.0 7.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEG46970.1 - 4.1e-07 29.6 3.8 1.1e-06 28.2 3.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger PX PF00787.24 CEG46970.1 - 6.6e-07 29.3 0.3 1.9e-06 27.8 0.3 1.8 1 1 0 1 1 1 1 PX domain zf-C3HC4 PF00097.25 CEG46970.1 - 1.7e-06 27.8 6.5 4.6e-06 26.4 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG46970.1 - 1.5e-05 24.7 3.8 3.2e-05 23.7 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG46970.1 - 6.3e-05 22.9 7.1 0.00016 21.6 7.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEG46970.1 - 8e-05 22.4 10.8 0.00018 21.3 9.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG46970.1 - 0.00036 20.5 1.9 0.00066 19.7 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CEG46970.1 - 0.0012 18.7 5.2 0.0036 17.2 5.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 CEG46970.1 - 0.013 15.7 5.8 0.066 13.4 5.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 CEG46970.1 - 0.052 13.4 10.1 0.15 12.0 8.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 MinE PF03776.14 CEG46970.1 - 0.098 12.7 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE RINGv PF12906.7 CEG46970.1 - 0.18 11.9 2.9 0.49 10.6 2.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 CEG46970.1 - 0.36 10.7 5.7 0.25 11.2 0.5 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CEG46970.1 - 0.48 10.1 6.1 1.1 9.0 6.1 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type OrfB_Zn_ribbon PF07282.11 CEG46970.1 - 2.7 8.0 5.0 24 4.9 0.7 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain SNARE_assoc PF09335.11 CEG46971.1 - 6.3e-20 71.9 10.1 6.3e-20 71.9 10.1 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein Ni_hydr_CYTB PF01292.20 CEG46971.1 - 0.028 14.0 0.2 0.028 14.0 0.2 2.2 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 CEG46971.1 - 5.3 7.7 9.8 5.1 7.7 5.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) HECT PF00632.25 CEG46973.1 - 2.9e-82 276.6 0.0 4.3e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRM_1 PF00076.22 CEG46974.1 - 1.6e-14 53.5 0.0 3.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CEG46974.1 - 2.3e-05 24.3 1.3 2.3e-05 24.3 1.3 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEG46974.1 - 0.00017 21.5 0.4 0.00036 20.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 CEG46974.1 - 0.059 13.0 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 CEG46974.1 - 0.13 12.0 0.6 0.25 11.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_65C PF03633.15 CEG46976.1 - 0.12 12.2 0.2 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain FeoA PF04023.14 CEG46976.1 - 0.2 11.9 1.5 0.3 11.4 0.6 1.8 2 0 0 2 2 2 0 FeoA domain Pkinase PF00069.25 CEG46977.1 - 1.5e-60 204.8 0.0 2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG46977.1 - 1.1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG46977.1 - 3.8e-06 26.4 0.0 0.00022 20.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 CEG46977.1 - 0.00013 22.5 0.1 0.00028 21.4 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG46977.1 - 0.00015 22.2 1.8 0.00026 21.4 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.23 CEG46977.1 - 0.024 14.6 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG46977.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PH_8 PF15409.6 CEG46977.1 - 0.071 13.4 0.7 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Seadorna_VP7 PF07387.11 CEG46977.1 - 0.15 11.1 0.4 0.26 10.3 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 ATG7_N PF16420.5 CEG46979.1 - 0.084 12.5 0.0 0.09 12.4 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus rve PF00665.26 CEG46980.1 - 5.1e-20 71.9 0.0 8.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG46980.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.7 1 1 0 1 1 1 0 Integrase core domain Thioredoxin PF00085.20 CEG46981.1 - 4.2e-37 126.3 1.1 9.3e-20 70.5 0.3 2.1 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CEG46981.1 - 2.5e-07 30.4 0.8 0.0041 16.5 0.2 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CEG46981.1 - 4.1e-07 30.2 0.7 0.0007 19.9 0.1 2.7 2 1 0 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 CEG46981.1 - 0.00037 20.6 1.6 0.013 15.7 0.1 2.8 2 0 0 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.21 CEG46981.1 - 0.0011 18.9 0.4 0.0024 17.8 0.1 1.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CEG46981.1 - 0.0024 18.3 1.4 0.037 14.5 0.1 3.0 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEG46981.1 - 0.0076 16.4 0.7 0.037 14.2 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 CEG46981.1 - 0.024 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Redoxin Hus1 PF04005.12 CEG46981.1 - 0.027 13.6 0.6 0.039 13.1 0.6 1.2 1 0 0 1 1 1 0 Hus1-like protein Thioredoxin_9 PF14595.6 CEG46981.1 - 0.038 13.8 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin RXLR_WY PF18634.1 CEG46983.1 - 1.7e-05 24.7 0.1 0.0051 16.7 0.0 2.4 2 0 0 2 2 2 2 RXLR phytopathogen effector protein WY-domain Fringe PF02434.16 CEG46984.1 - 1.4e-14 54.2 0.2 2.5e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CEG46984.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase F-box PF00646.33 CEG46985.1 - 2e-05 24.3 1.0 3.6e-05 23.5 1.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEG46985.1 - 0.00013 21.8 0.8 0.00026 20.8 0.8 1.5 1 0 0 1 1 1 1 F-box-like DUF5526 PF17664.1 CEG46985.1 - 0.046 13.3 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5526) ParcG PF10274.9 CEG46986.1 - 3.7e-36 125.0 0.0 7.7e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Parkin co-regulated protein GAD-like PF08887.11 CEG46986.1 - 0.031 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain RXLR_WY PF18634.1 CEG46988.1 - 0.00056 19.8 0.1 0.28 11.1 0.1 2.7 2 0 0 2 2 2 2 RXLR phytopathogen effector protein WY-domain Tricorn_C1 PF14684.6 CEG46991.1 - 0.011 15.8 0.2 0.038 14.1 0.2 1.8 1 0 0 1 1 1 0 Tricorn protease C1 domain DsrC PF04358.13 CEG46991.1 - 0.03 14.8 0.0 0.074 13.6 0.0 1.6 1 0 0 1 1 1 0 DsrC like protein TGase_elicitor PF16683.5 CEG46992.1 - 1.2e-35 123.0 0.0 1.3e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor TBCC PF07986.12 CEG46993.1 - 0.037 13.8 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor C SNAD1 PF18744.1 CEG46993.1 - 0.051 13.4 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 Ank_2 PF12796.7 CEG46999.1 - 9.4e-36 122.3 0.6 7.2e-17 61.8 0.0 5.8 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG46999.1 - 7e-30 99.8 3.9 2.3e-06 27.5 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CEG46999.1 - 1.2e-29 101.4 9.4 3e-09 36.9 0.0 8.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 CEG46999.1 - 1.4e-27 95.7 8.4 2.7e-09 37.4 0.0 7.4 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG46999.1 - 1e-25 89.4 12.6 7.9e-07 29.2 0.5 7.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 CEG46999.1 - 2.8e-21 76.3 1.4 1.3e-15 58.1 0.1 3.7 2 1 0 2 2 2 2 TIR domain TIR PF01582.20 CEG46999.1 - 0.00058 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 TIR domain DUF986 PF06173.12 CEG46999.1 - 0.023 14.8 1.1 3.7 7.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF986) DUF3301 PF11743.8 CEG46999.1 - 0.22 11.2 1.6 18 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Cullin PF00888.22 CEG47000.1 - 3e-178 594.3 26.2 1.6e-176 588.6 26.2 2.1 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEG47000.1 - 2.4e-27 94.7 1.8 8.4e-27 93.0 1.8 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DNA_repr_REX1B PF14966.6 CEG47000.1 - 0.018 15.7 5.1 1.5 9.5 0.0 4.3 4 0 0 4 4 4 0 DNA repair REX1-B HBD PF18534.1 CEG47000.1 - 0.073 13.2 0.5 0.41 10.8 0.1 2.6 2 0 0 2 2 2 0 Helical bundle domain UDPGT PF00201.18 CEG47001.1 - 1.1e-12 47.5 0.0 1.2e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEG47001.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ank_2 PF12796.7 CEG47002.1 - 8.8e-35 119.2 3.6 2.4e-15 56.9 0.2 5.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47002.1 - 1.2e-28 99.1 8.4 8.1e-09 35.8 0.0 7.9 3 2 5 8 8 8 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 CEG47002.1 - 3.7e-28 98.5 0.1 1.1e-17 64.7 0.0 3.4 2 1 0 2 2 2 2 TIR domain Ank_3 PF13606.6 CEG47002.1 - 3e-26 88.6 9.6 0.00013 22.1 0.1 9.6 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.30 CEG47002.1 - 2.8e-22 78.1 16.5 3.7e-06 27.1 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 CEG47002.1 - 2.3e-21 75.5 10.6 7.8e-06 26.1 0.0 6.6 5 1 2 7 7 7 5 Ankyrin repeats (many copies) TIR PF01582.20 CEG47002.1 - 3.2e-06 27.1 0.0 2.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 CEG47002.1 - 9.7e-06 25.9 1.0 0.17 12.2 0.1 3.4 3 1 0 3 3 3 2 MTH538 TIR-like domain (DUF1863) HTH_Tnp_4 PF13613.6 CEG47004.1 - 0.0096 15.6 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.10 CEG47004.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_33 PF13592.6 CEG47004.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ank_2 PF12796.7 CEG47005.1 - 1.8e-45 153.5 0.0 1.4e-15 57.6 0.0 6.2 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47005.1 - 6.6e-36 122.2 0.9 9.6e-10 38.8 0.0 7.7 5 1 2 7 7 7 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 CEG47005.1 - 1.5e-31 109.4 0.0 5.1e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 TIR domain Ank_3 PF13606.6 CEG47005.1 - 5.2e-31 103.2 0.8 3.8e-05 23.8 0.0 9.5 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 CEG47005.1 - 6.2e-27 92.8 4.3 0.0001 22.6 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 CEG47005.1 - 6.3e-24 83.7 4.0 1.6e-06 28.2 0.0 7.7 5 1 2 7 7 7 3 Ankyrin repeats (many copies) TIR PF01582.20 CEG47005.1 - 1.7e-08 34.5 0.0 3.1e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 CEG47005.1 - 2.8e-05 24.4 0.1 0.0074 16.6 0.1 3.7 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) UreF PF01730.16 CEG47005.1 - 0.1 13.2 0.8 0.63 10.6 0.2 2.5 2 0 0 2 2 2 0 UreF Aldedh PF00171.22 CEG47007.1 - 1.5e-22 79.7 0.0 1.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Psu PF07455.11 CEG47007.1 - 0.0027 17.3 0.2 0.012 15.3 0.1 1.8 1 1 1 2 2 2 1 Phage polarity suppression protein (Psu) RasGAP PF00616.19 CEG47007.1 - 0.014 15.1 0.0 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase Archease PF01951.16 CEG47007.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Archease protein family (MTH1598/TM1083) FAD_binding_2 PF00890.24 CEG47009.1 - 8.3e-78 262.3 0.9 1.1e-77 261.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEG47009.1 - 3e-09 36.5 0.5 0.00026 20.3 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEG47009.1 - 1.1e-06 28.5 0.8 8.1e-06 25.7 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CEG47009.1 - 0.00065 18.9 1.7 0.02 14.0 0.6 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CEG47009.1 - 0.0012 19.0 0.3 0.0033 17.6 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CEG47009.1 - 0.012 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Succ_DH_flav_C PF02910.20 CEG47009.1 - 0.016 15.2 0.1 0.074 13.0 0.1 2.0 1 1 0 1 1 1 0 Fumarate reductase flavoprotein C-term Lycopene_cycl PF05834.12 CEG47009.1 - 0.047 12.7 0.3 0.068 12.2 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CEG47009.1 - 0.097 12.0 1.7 2.1 7.6 1.7 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 CEG47009.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 CEG47009.1 - 0.2 10.9 1.7 2.2 7.4 0.3 3.0 3 1 0 3 3 3 0 Thi4 family p450 PF00067.22 CEG47010.1 - 4.1e-80 269.8 0.2 5.2e-80 269.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CEG47011.1 - 8.4e-73 245.7 0.0 1.1e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RCC1_2 PF13540.6 CEG47012.1 - 7.8e-38 127.5 45.8 3.1e-09 36.4 0.2 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CEG47012.1 - 5.1e-05 23.8 31.5 0.034 14.8 0.0 7.7 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat ATG13 PF10033.9 CEG47013.1 - 1e-22 81.1 0.4 8.5e-15 55.1 0.1 2.7 1 1 1 2 2 2 2 Autophagy-related protein 13 DUF4203 PF13886.6 CEG47014.1 - 1.2e-46 159.0 28.3 1.4e-46 158.7 28.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF308 PF03729.13 CEG47014.1 - 0.019 15.3 6.6 0.019 15.3 6.6 4.6 3 1 3 6 6 6 0 Short repeat of unknown function (DUF308) Trp_oprn_chp PF09534.10 CEG47014.1 - 0.094 12.5 1.5 0.83 9.4 0.0 2.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_2_3 PF16080.5 CEG47014.1 - 3.7 7.4 7.7 0.67 9.8 1.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 EamA PF00892.20 CEG47015.1 - 5.9e-13 49.2 38.3 7.8e-10 39.1 14.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family PEN-2 PF10251.9 CEG47015.1 - 0.42 11.0 4.3 0.66 10.4 0.1 3.0 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase LSM14 PF12701.7 CEG47018.1 - 3.2e-26 91.2 0.0 5.8e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CEG47018.1 - 2.1e-05 25.4 0.1 2.1e-05 25.4 0.1 3.2 2 1 1 3 3 3 1 FDF domain Cyt-b5 PF00173.28 CEG47019.1 - 1.8e-10 40.8 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CDC24_OB2 PF17245.2 CEG47020.1 - 8.3e-24 84.6 0.1 2.4e-23 83.1 0.1 1.8 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 CEG47020.1 - 1.4e-13 51.0 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 RabGAP-TBC PF00566.18 CEG47021.1 - 1.8e-11 44.2 0.0 7.6e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain WW PF00397.26 CEG47021.1 - 2.4e-06 27.5 1.0 4.8e-06 26.5 1.0 1.5 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.20 CEG47021.1 - 0.052 14.1 0.0 0.33 11.5 0.0 2.2 1 1 0 1 1 1 0 Rhodanese-like domain Tetraspanin PF00335.20 CEG47023.1 - 0.094 12.4 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 Tetraspanin family RPS31 PF17067.5 CEG47024.1 - 0.051 13.7 0.9 0.051 13.7 0.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S31e bZIP_2 PF07716.15 CEG47025.1 - 0.1 12.7 4.7 0.32 11.1 4.7 1.9 1 1 0 1 1 1 0 Basic region leucine zipper RRM_1 PF00076.22 CEG47026.1 - 0.0091 15.8 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH_2 PF06294.11 CEG47027.1 - 1.3e-28 99.0 0.1 3.5e-28 97.6 0.1 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CEG47027.1 - 8.7e-07 28.7 0.0 2.9e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain BPL_N PF09825.9 CEG47027.1 - 0.043 12.9 0.2 0.081 12.0 0.2 1.5 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Pectate_lyase PF03211.13 CEG47028.1 - 7.2e-38 130.2 0.1 9.9e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase DHHC PF01529.20 CEG47032.1 - 8.9e-20 71.2 8.6 1.3e-19 70.6 8.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Pex24p PF06398.11 CEG47032.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin HIG_1_N PF04588.13 CEG47032.1 - 6.4 7.1 9.2 51 4.2 0.3 3.4 2 1 1 3 3 3 0 Hypoxia induced protein conserved region MscS_TM PF12794.7 CEG47032.1 - 8.8 5.1 8.4 0.65 8.8 0.6 2.1 1 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF842 PF05811.13 CEG47033.1 - 1.6e-41 141.1 9.4 1.8e-41 140.9 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-Tim10_DDP PF02953.15 CEG47033.1 - 0.00094 18.8 5.2 0.0011 18.6 2.1 2.6 3 1 0 3 3 3 1 Tim10/DDP family zinc finger CREPT PF16566.5 CEG47033.1 - 0.003 17.7 0.9 0.0045 17.2 0.9 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour GF_recep_IV PF14843.6 CEG47033.1 - 0.0093 15.8 3.8 0.012 15.5 3.8 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV MyTH4 PF00784.17 CEG47033.1 - 0.013 15.9 0.3 0.021 15.3 0.3 1.4 1 0 0 1 1 1 0 MyTH4 domain Ran-binding PF05508.11 CEG47033.1 - 0.031 13.3 0.1 0.041 12.9 0.1 1.2 1 0 0 1 1 1 0 RanGTP-binding protein ZYG-11_interact PF05884.12 CEG47033.1 - 0.061 12.7 0.2 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 HK97-gp10_like PF04883.12 CEG47033.1 - 0.064 14.2 0.2 0.72 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component 7TMR-HDED PF07697.11 CEG47033.1 - 0.07 13.2 1.0 0.12 12.5 0.9 1.5 1 1 0 1 1 1 0 7TM-HD extracellular MutS_I PF01624.20 CEG47033.1 - 0.08 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 MutS domain I Aminotran_1_2 PF00155.21 CEG47033.1 - 0.081 12.1 0.9 0.16 11.1 0.7 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II RasGAP_C PF03836.15 CEG47033.1 - 0.083 13.0 1.2 0.14 12.3 1.0 1.5 1 1 0 1 1 1 0 RasGAP C-terminus UPF0154 PF03672.13 CEG47033.1 - 0.14 12.2 2.2 0.17 11.9 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Remorin_C PF03763.13 CEG47033.1 - 0.15 12.0 1.8 0.14 12.1 0.6 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region Ribosomal_S30AE PF02482.19 CEG47033.1 - 0.15 12.9 1.0 4.7 8.1 0.2 2.6 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Apolipoprotein PF01442.18 CEG47033.1 - 0.16 11.8 3.9 0.48 10.3 3.9 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Col_cuticle_N PF01484.17 CEG47033.1 - 0.45 10.6 1.7 0.79 9.8 0.5 2.0 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain OmpH PF03938.14 CEG47033.1 - 0.98 9.8 8.6 2 8.8 8.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NCBP3 PF10309.9 CEG47034.1 - 3.2e-13 49.3 0.1 9.5e-13 47.8 0.1 1.9 2 0 0 2 2 2 1 Nuclear cap-binding protein subunit 3 Methyltransf_FA PF12248.8 CEG47034.1 - 6.9e-09 36.0 0.2 2.2e-08 34.4 0.2 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase RNA_bind PF08675.11 CEG47034.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain WD-3 PF09765.9 CEG47035.1 - 2.4e-84 283.1 0.0 3.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 CEG47035.1 - 1.3e-26 92.6 3.8 5.9e-26 90.4 3.8 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 CEG47035.1 - 0.0014 19.0 3.7 0.0014 19.0 3.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-ANAPC11 PF12861.7 CEG47035.1 - 0.0084 16.1 0.8 0.034 14.2 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEG47035.1 - 0.23 11.8 6.9 0.86 9.9 6.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain IF3_N PF05198.16 CEG47036.1 - 5.7e-16 58.6 0.1 9.5e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 CEG47036.1 - 1.5e-08 34.5 0.2 1.5e-08 34.5 0.2 2.2 1 1 1 2 2 2 1 Translation initiation factor IF-3, C-terminal domain APOBEC4 PF18775.1 CEG47036.1 - 0.027 14.6 0.6 0.085 13.0 0.1 2.1 2 0 0 2 2 2 0 APOBEC4 ABC_transp_aux PF09822.9 CEG47036.1 - 0.057 12.9 0.5 9.2 5.6 0.1 2.3 1 1 1 2 2 2 0 ABC-type uncharacterized transport system NAD1 PF18778.1 CEG47036.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 CEG47036.1 - 0.11 12.7 0.2 0.26 11.4 0.2 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 RPN7 PF10602.9 CEG47037.1 - 3.2e-50 170.2 1.3 3.2e-50 170.2 1.3 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CEG47037.1 - 9.1e-16 58.3 0.0 2.1e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.6 CEG47037.1 - 0.0018 18.5 2.1 0.014 15.6 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ComR_TPR PF18710.1 CEG47037.1 - 0.0044 16.6 0.0 0.029 13.9 0.0 2.0 1 1 1 2 2 2 1 ComR tetratricopeptide TPR_7 PF13176.6 CEG47037.1 - 0.014 15.3 0.0 0.069 13.2 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG47037.1 - 0.043 14.0 0.7 0.29 11.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG47037.1 - 0.087 13.5 0.1 0.61 10.8 0.1 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG47037.1 - 0.34 11.1 7.3 0.62 10.3 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 CEG47038.1 - 3.4e-36 124.9 0.6 5e-36 124.3 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEG47038.1 - 1.6e-16 60.5 7.6 3.9e-16 59.2 7.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SHE3 PF17078.5 CEG47038.1 - 0.014 15.2 1.3 1.9 8.2 0.5 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 CEG47038.1 - 0.34 11.1 5.3 0.99 9.6 5.3 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 CEG47038.1 - 0.58 10.4 7.7 0.63 10.3 5.7 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain YabA PF06156.13 CEG47038.1 - 2.3 8.9 6.1 3.2 8.4 4.5 2.1 2 0 0 2 2 2 0 Initiation control protein YabA MitMem_reg PF13012.6 CEG47039.1 - 4e-22 78.7 0.0 1.8e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEG47039.1 - 5.1e-13 49.0 0.0 8.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1894 PF08979.11 CEG47039.1 - 0.038 14.4 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) ELMO_CED12 PF04727.13 CEG47040.1 - 6.7e-32 111.0 0.0 8.4e-30 104.2 0.0 2.3 2 0 0 2 2 2 1 ELMO/CED-12 family PH PF00169.29 CEG47040.1 - 4.5e-20 72.1 0.1 2.5e-15 56.9 0.0 3.1 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 CEG47040.1 - 0.0049 17.3 0.1 0.41 11.1 0.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain Mso1_C PF14477.6 CEG47040.1 - 0.014 15.8 2.4 0.048 14.1 2.3 2.0 1 1 0 1 1 1 0 Membrane-polarising domain of Mso1 PH_3 PF14593.6 CEG47040.1 - 0.033 14.3 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 PH domain UPF0086 PF01868.16 CEG47043.1 - 4.5e-07 29.7 0.0 1.7e-06 27.8 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function UPF0086 CWC25 PF12542.8 CEG47043.1 - 0.0045 17.9 2.3 0.0045 17.9 0.6 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing factor DUF4460 PF14687.6 CEG47045.1 - 4e-05 23.6 0.3 0.00061 19.8 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4460) Arc_trans_TRASH PF08394.10 CEG47046.1 - 0.0065 16.8 2.8 0.0092 16.3 2.8 1.2 1 0 0 1 1 1 1 Archaeal TRASH domain AA_permease_2 PF13520.6 CEG47047.1 - 2.5e-28 99.1 33.6 3.2e-28 98.7 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG47047.1 - 2.2e-12 46.4 26.1 1.1e-08 34.1 8.4 2.1 2 0 0 2 2 2 2 Amino acid permease Glyco_hydro81C PF17652.1 CEG47048.1 - 9.6e-91 304.6 4.0 1.4e-90 304.0 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG47048.1 - 3.4e-35 121.7 0.6 3.2e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain ESF1 PF18209.1 CEG47048.1 - 3 7.9 4.1 0.54 10.2 0.4 1.7 2 0 0 2 2 2 0 Embryo surrounding factor 1 NUDIX PF00293.28 CEG47049.1 - 2.6e-09 37.2 0.0 3.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain VPS13_C PF16909.5 CEG47050.1 - 2.4e-23 82.8 6.7 1.4e-21 77.1 0.5 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 CEG47050.1 - 1.3e-21 76.8 0.2 2.9e-13 50.0 0.0 2.8 2 0 0 2 2 2 2 C2 domain SHR-BD PF06650.12 CEG47050.1 - 2.4e-17 63.2 0.1 2.7e-16 59.7 0.1 2.5 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_1 PF00036.32 CEG47050.1 - 6.3e-12 44.1 1.5 1.1e-05 24.6 0.8 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CEG47050.1 - 1.7e-11 43.1 1.3 5.1e-05 22.9 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CEG47050.1 - 3.1e-11 43.6 1.8 1.1e-10 41.8 1.8 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG47050.1 - 7.4e-08 31.5 0.9 0.0059 16.0 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG47050.1 - 2.2e-05 24.2 0.9 0.021 14.7 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair NT-C2 PF10358.9 CEG47050.1 - 0.0031 17.2 0.5 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins EF-hand_10 PF14788.6 CEG47050.1 - 0.33 10.9 2.3 0.54 10.2 1.1 2.0 2 0 0 2 2 2 0 EF hand Exo_endo_phos PF03372.23 CEG47051.1 - 7.9e-10 38.6 0.0 1.1e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HicB-like_2 PF15970.5 CEG47051.1 - 0.14 12.4 0.1 12 6.2 0.0 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system zf-RanBP PF00641.18 CEG47052.1 - 0.00013 21.3 1.3 0.00028 20.1 1.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FAIM1 PF06905.13 CEG47052.1 - 0.00015 21.6 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) MecA_N PF05223.11 CEG47053.1 - 0.31 11.3 6.0 0.13 12.5 1.3 2.2 1 1 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF2175 PF09943.9 CEG47053.1 - 2 8.8 5.8 0.54 10.6 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5521 PF17659.1 CEG47053.1 - 7.4 4.3 8.1 9.2 4.0 8.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF755 PF05501.11 CEG47053.1 - 7.8 6.8 26.4 8 6.8 10.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RRS1 PF04939.12 CEG47055.1 - 0.017 15.0 1.9 0.022 14.6 1.9 1.3 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Tctex-1 PF03645.13 CEG47058.1 - 7.3e-23 80.8 1.3 1.2e-22 80.1 1.3 1.3 1 0 0 1 1 1 1 Tctex-1 family ATP-synt_DE_N PF02823.16 CEG47058.1 - 5.1e-10 39.1 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF4100 PF13352.6 CEG47059.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Ank_2 PF12796.7 CEG47061.1 - 2.9e-17 63.0 0.0 2e-11 44.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG47061.1 - 2.7e-15 56.2 0.0 1.3e-05 25.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG47061.1 - 1.7e-11 44.4 0.0 0.014 16.0 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47061.1 - 2.7e-11 42.7 0.1 0.013 16.0 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 CEG47061.1 - 3.1e-11 43.2 12.5 5e-11 42.6 12.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank PF00023.30 CEG47061.1 - 3.8e-10 39.8 1.2 0.00035 20.9 0.2 5.0 3 1 2 5 5 5 2 Ankyrin repeat PDZ PF00595.24 CEG47061.1 - 0.0021 18.4 0.0 0.0055 17.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG47061.1 - 0.033 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain FYVE_2 PF02318.16 CEG47061.1 - 1.2 9.4 12.0 3.4 7.9 12.0 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Fez1 PF06818.15 CEG47062.1 - 0.00079 19.9 18.5 0.00079 19.9 18.5 6.9 2 2 4 6 6 6 4 Fez1 Spc7 PF08317.11 CEG47062.1 - 0.0024 16.8 18.7 0.0024 16.8 18.7 7.0 1 1 6 7 7 7 5 Spc7 kinetochore protein Psu PF07455.11 CEG47062.1 - 2.8 7.5 9.9 5.3 6.6 0.3 3.9 3 0 0 3 3 3 0 Phage polarity suppression protein (Psu) tRNA-synt_1g PF09334.11 CEG47063.1 - 5.2e-99 331.6 0.6 4.5e-55 187.0 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEG47063.1 - 4.7e-36 124.2 1.3 9.5e-22 77.0 0.0 3.0 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 CEG47063.1 - 3.3e-28 97.6 0.0 7.2e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 CEG47063.1 - 2.4e-15 56.7 0.2 2.7e-07 30.2 0.3 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CEG47063.1 - 5.4e-08 32.9 0.9 3.9e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 CEG47063.1 - 2.7e-05 23.3 0.0 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) YL1_C PF08265.11 CEG47063.1 - 0.13 12.0 0.1 0.44 10.4 0.1 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain FHA PF00498.26 CEG47065.1 - 2.4e-16 59.8 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG47065.1 - 2.3e-09 37.5 0.0 5.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain EnY2 PF10163.9 CEG47066.1 - 7.8e-28 96.7 0.3 9.7e-28 96.4 0.3 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF29 PF01724.16 CEG47066.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF29 Ribosomal_S16 PF00886.19 CEG47067.1 - 1e-24 86.3 0.1 1.4e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Nop14 PF04147.12 CEG47068.1 - 4.5e-193 643.9 47.7 5.7e-193 643.6 47.7 1.1 1 0 0 1 1 1 1 Nop14-like family MIF4G PF02854.19 CEG47076.1 - 2.1e-44 151.7 4.9 2.1e-44 151.7 4.9 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CEG47076.1 - 2.4e-17 62.9 0.5 1.2e-16 60.7 0.1 2.4 2 0 0 2 2 2 1 MA3 domain PAM2 PF07145.15 CEG47076.1 - 0.06 13.1 8.5 0.96 9.3 0.2 3.7 3 0 0 3 3 3 0 Ataxin-2 C-terminal region STAT_bind PF02864.15 CEG47078.1 - 0.021 15.4 0.0 0.066 13.8 0.0 1.7 2 0 0 2 2 2 0 STAT protein, DNA binding domain Pox_A3L PF05288.11 CEG47087.1 - 0.14 12.2 1.0 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A3L Protein Hydrolase_4 PF12146.8 CEG47088.1 - 1.1e-52 178.8 0.0 1.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG47088.1 - 1.3e-11 44.6 0.2 1.2e-08 34.9 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG47088.1 - 2.1e-11 44.9 0.0 2.9e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CEG47088.1 - 0.00011 22.1 5.4 0.02 14.7 0.3 3.5 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 CEG47088.1 - 0.0005 19.7 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CEG47088.1 - 0.0025 17.3 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 CEG47088.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ribosomal_L34e PF01199.18 CEG47091.1 - 1.8e-40 137.1 9.1 2.4e-40 136.7 9.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FAT PF02259.23 CEG47092.1 - 1.8e-78 264.2 2.1 3.6e-78 263.2 2.1 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CEG47092.1 - 7.8e-73 245.4 0.1 1.4e-72 244.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CEG47092.1 - 1.8e-44 151.5 0.0 1.8e-42 145.0 0.0 4.3 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CEG47092.1 - 1.9e-43 146.9 1.1 1.1e-42 144.4 0.2 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 CEG47092.1 - 4.6e-09 36.5 5.8 0.0071 16.7 0.0 7.8 9 1 1 10 10 9 2 HEAT repeats HEAT PF02985.22 CEG47092.1 - 1.9e-05 24.5 19.5 0.19 12.1 0.0 9.3 10 0 0 10 10 9 1 HEAT repeat Cnd1 PF12717.7 CEG47092.1 - 0.00019 21.5 1.8 0.43 10.6 0.3 4.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEG47092.1 - 0.002 16.8 1.9 0.14 10.7 0.2 3.4 3 0 0 3 3 3 1 Adaptin N terminal region FATC PF02260.20 CEG47092.1 - 0.031 14.1 0.1 0.12 12.2 0.1 2.1 1 0 0 1 1 1 0 FATC domain Arm PF00514.23 CEG47092.1 - 0.081 13.0 0.2 39 4.5 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 CEG47092.1 - 0.38 10.6 3.6 1.2 9.0 0.3 3.7 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FYVE PF01363.21 CEG47094.1 - 6.1e-10 39.1 11.6 1.6e-09 37.8 11.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Borrelia_P83 PF05262.11 CEG47094.1 - 0.00016 20.3 18.4 0.00023 19.8 18.4 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein Presenilin PF01080.17 CEG47094.1 - 0.51 9.0 13.5 0.71 8.6 13.5 1.2 1 0 0 1 1 1 0 Presenilin AAA_15 PF13175.6 CEG47094.1 - 2.1 7.9 9.6 2.9 7.5 9.6 1.1 1 0 0 1 1 1 0 AAA ATPase domain LMBR1 PF04791.16 CEG47094.1 - 2.5 6.9 11.8 3.5 6.4 11.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CEG47094.1 - 5.2 6.5 15.8 9 5.8 15.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemY_N PF07219.13 CEG47098.1 - 0.006 16.8 0.1 0.0077 16.4 0.1 1.1 1 0 0 1 1 1 1 HemY protein N-terminus Trm112p PF03966.16 CEG47101.1 - 7.5e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 1 0 1 1 1 1 Trm112p-like protein CIA30 PF08547.12 CEG47102.1 - 2.8e-32 112.0 0.0 5.6e-32 111.0 0.0 1.5 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Pkinase PF00069.25 CEG47103.1 - 5.8e-67 225.8 0.0 7.7e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47103.1 - 3.2e-26 92.2 0.1 9.8e-26 90.6 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG47103.1 - 0.00063 19.1 0.0 0.0032 16.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEG47103.1 - 0.015 14.2 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CEG47103.1 - 0.077 12.6 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CEG47103.1 - 0.13 11.6 0.5 0.28 10.5 0.5 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAS-6_N PF16531.5 CEG47104.1 - 1.2e-27 96.4 2.5 2.3e-27 95.4 2.5 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Gemini_AL1 PF00799.20 CEG47105.1 - 0.0081 16.5 0.8 0.031 14.6 0.8 2.0 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain CCM2_C PF16545.5 CEG47106.1 - 0.022 15.3 0.3 3.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Reprolysin_5 PF13688.6 CEG47107.1 - 0.029 14.5 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 Metallo-peptidase family M12 NUDIX PF00293.28 CEG47110.1 - 4.1e-18 65.7 0.0 5.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Pam16 PF03656.13 CEG47111.1 - 4.3e-21 75.3 0.4 5.1e-21 75.0 0.4 1.0 1 0 0 1 1 1 1 Pam16 HA2 PF04408.23 CEG47112.1 - 3.3e-26 91.7 0.2 7.1e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG47112.1 - 9.6e-20 70.7 0.0 3.6e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG47112.1 - 7.5e-10 39.1 0.0 1.9e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG47112.1 - 7.3e-08 32.4 0.6 1.6e-07 31.3 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CEG47112.1 - 9e-06 24.9 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CEG47112.1 - 1.4e-05 25.4 0.2 2.8e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEG47112.1 - 9.5e-05 22.7 0.1 0.00036 20.8 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CEG47112.1 - 0.0011 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEG47112.1 - 0.0072 16.3 0.8 0.059 13.3 0.2 2.5 2 1 0 2 2 2 1 NACHT domain SRP54 PF00448.22 CEG47112.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 CEG47112.1 - 0.018 14.9 0.0 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 Helicase ABC_tran PF00005.27 CEG47112.1 - 0.025 15.1 0.0 0.081 13.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Herpes_ori_bp PF02399.15 CEG47112.1 - 0.03 12.4 0.1 0.046 11.8 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Sigma54_activat PF00158.26 CEG47112.1 - 0.059 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CEG47112.1 - 0.11 12.5 0.2 5.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CEG47112.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CEG47112.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 CEG47112.1 - 0.16 11.1 0.5 5 6.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.6 CEG47112.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CEG47113.1 - 2.6e-39 134.8 0.9 4.6e-39 134.0 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG47113.1 - 1.7e-25 89.5 0.1 3.4e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG47113.1 - 2.6e-08 34.1 0.0 4.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEG47113.1 - 0.012 15.8 0.7 0.14 12.4 0.7 2.4 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CEG47113.1 - 0.013 14.9 1.3 0.03 13.7 0.5 1.9 1 1 1 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 CEG47113.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 CEG47113.1 - 0.048 13.1 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein PX PF00787.24 CEG47114.1 - 7.6e-10 38.8 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF4107 PF13389.6 CEG47114.1 - 0.13 12.4 0.7 0.35 11.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) zf-MYND PF01753.18 CEG47115.1 - 5.2e-09 36.1 14.1 5.2e-09 36.1 14.1 2.6 2 1 0 2 2 2 1 MYND finger SAP PF02037.27 CEG47115.1 - 0.00014 21.5 0.1 0.00041 20.0 0.1 1.8 1 0 0 1 1 1 1 SAP domain FTCD_C PF04961.12 CEG47115.1 - 0.017 14.9 0.5 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase HeH PF12949.7 CEG47115.1 - 0.024 14.3 0.0 0.08 12.7 0.0 2.0 1 0 0 1 1 1 0 HeH/LEM domain zf-C6H2 PF15801.5 CEG47115.1 - 0.045 14.1 9.4 0.2 12.0 9.4 2.1 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ank_2 PF12796.7 CEG47116.1 - 8.8e-37 125.6 13.3 1.2e-13 51.4 0.1 6.3 3 1 4 7 7 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47116.1 - 3.7e-27 94.3 15.3 4.4e-06 27.1 0.0 7.1 2 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG47116.1 - 7.9e-27 93.0 14.2 1.5e-07 31.5 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47116.1 - 2.3e-19 67.4 16.1 0.00084 19.6 0.6 9.8 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 CEG47116.1 - 2.8e-19 68.6 23.2 0.00045 20.5 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat IQ PF00612.27 CEG47116.1 - 1.1e-13 49.7 82.1 0.0021 17.7 0.1 13.5 13 0 0 13 13 13 8 IQ calmodulin-binding motif TPR_2 PF07719.17 CEG47116.1 - 0.003 17.6 1.2 0.033 14.3 0.7 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG47116.1 - 0.014 15.6 3.9 0.53 10.6 1.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.26 CEG47116.1 - 0.017 15.2 4.8 1.4 9.1 0.0 3.7 4 0 0 4 4 4 0 WW domain TPR_1 PF00515.28 CEG47116.1 - 0.042 13.7 0.3 0.16 11.8 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG47116.1 - 0.047 14.5 0.1 61 4.8 0.0 4.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG47116.1 - 0.58 9.9 1.7 9 6.1 0.1 2.5 2 0 0 2 2 2 0 TPR repeat FAST_2 PF08368.12 CEG47116.1 - 0.66 10.8 2.9 22 5.9 2.4 3.4 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 Elicitin PF00964.17 CEG47118.1 - 5.6e-12 45.6 2.2 8.3e-12 45.1 2.2 1.3 1 0 0 1 1 1 1 Elicitin PQ-loop PF04193.14 CEG47119.1 - 5.4e-30 103.0 18.8 3.5e-16 58.7 7.4 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4131 PF13567.6 CEG47119.1 - 0.74 9.4 10.2 2.1 8.0 2.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UPF0114 PF03350.16 CEG47119.1 - 5 7.4 7.6 2.2 8.5 1.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein family, UPF0114 Pkinase PF00069.25 CEG47120.1 - 6.7e-51 173.2 0.0 5.5e-46 157.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47120.1 - 2e-19 69.9 0.0 1.3e-13 50.8 0.0 3.2 2 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG47120.1 - 0.0093 15.3 0.1 0.066 12.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEG47120.1 - 0.16 11.3 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.19 CEG47121.1 - 5.9e-10 39.5 2.7 8.5e-10 39.0 2.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EGF_2 PF07974.13 CEG47122.1 - 9.2e-08 32.3 42.7 2.9e-05 24.3 8.4 5.5 5 0 0 5 5 5 4 EGF-like domain EGF PF00008.27 CEG47122.1 - 0.037 14.3 3.7 0.037 14.3 3.7 4.9 6 0 0 6 6 6 0 EGF-like domain Laminin_EGF PF00053.24 CEG47122.1 - 0.85 9.8 29.9 0.91 9.7 14.0 3.3 3 1 0 3 3 3 0 Laminin EGF domain EF-hand_7 PF13499.6 CEG47123.1 - 3.9e-15 56.0 3.1 0.00014 22.2 0.0 7.8 7 1 1 8 8 8 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG47123.1 - 2.5e-14 51.9 3.8 0.012 15.4 0.0 7.3 8 0 0 8 8 8 4 EF-hand domain EF-hand_1 PF00036.32 CEG47123.1 - 3.2e-08 32.5 0.3 0.33 10.6 0.0 5.9 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 CEG47123.1 - 7.2e-05 22.6 0.1 22 5.0 0.0 6.1 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_2 PF09068.11 CEG47123.1 - 0.0013 18.9 0.0 0.016 15.4 0.0 2.7 2 1 0 2 2 2 1 EF hand DUF3846 PF12957.7 CEG47123.1 - 0.0077 16.5 0.1 0.054 13.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3846) ToxS PF17323.2 CEG47123.1 - 0.12 12.1 0.0 0.84 9.3 0.1 2.1 2 0 0 2 2 2 0 Trans-membrane regulatory protein ToxS EF-hand_5 PF13202.6 CEG47123.1 - 0.14 11.7 0.2 29 4.4 0.0 3.9 4 0 0 4 4 4 0 EF hand EamA PF00892.20 CEG47124.1 - 0.79 9.9 10.6 0.05 13.8 5.8 1.4 2 0 0 2 2 2 0 EamA-like transporter family TMEM65 PF10507.9 CEG47125.1 - 1.1e-37 128.3 4.6 2.4e-37 127.2 4.6 1.6 1 0 0 1 1 1 1 Transmembrane protein 65 B12D PF06522.11 CEG47125.1 - 1.9e-13 50.0 0.0 4.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit EF-hand_1 PF00036.32 CEG47125.1 - 0.007 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CEG47125.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair DUF4455 PF14643.6 CEG47125.1 - 0.046 12.4 0.3 0.42 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) EF-hand_6 PF13405.6 CEG47125.1 - 0.097 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain RPAP3_C PF13877.6 CEG47125.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 EF-hand_7 PF13499.6 CEG47125.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair Beach PF02138.18 CEG47126.1 - 1e-35 123.5 0.0 1.7e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CEG47126.1 - 1.9e-05 25.3 0.2 0.00053 20.7 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Pkinase PF00069.25 CEG47126.1 - 0.0003 20.3 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Strumpellin PF10266.9 CEG47127.1 - 0 1452.4 0.8 0 1452.2 0.8 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DUF4375 PF14300.6 CEG47127.1 - 4.6 7.5 5.9 33 4.8 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PhoU_div PF01865.16 CEG47127.1 - 9.7 5.5 9.6 2.2 7.6 3.7 2.9 3 1 0 3 3 3 0 Protein of unknown function DUF47 EamA PF00892.20 CEG47128.1 - 1.5e-27 96.4 37.4 6.3e-15 55.6 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family PPR_2 PF13041.6 CEG47129.1 - 2.8e-27 94.7 7.0 7.1e-05 22.9 0.0 8.2 3 2 6 9 9 9 7 PPR repeat family PPR PF01535.20 CEG47129.1 - 1.3e-24 84.6 3.8 0.0071 16.5 0.0 8.5 10 0 0 10 10 10 6 PPR repeat PPR_3 PF13812.6 CEG47129.1 - 9.4e-21 73.7 0.1 1.4e-06 28.3 0.2 5.6 3 1 4 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 CEG47129.1 - 1.5e-13 50.6 1.0 4.1e-07 29.6 0.2 3.5 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEG47129.1 - 5.2e-09 35.7 0.0 0.01 15.5 0.1 5.3 6 0 0 6 6 6 2 PPR repeat Utp13 PF08625.11 CEG47129.1 - 0.0072 16.2 0.3 5.2 7.0 0.0 2.8 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain UTP15_C PF09384.10 CEG47129.1 - 0.071 12.8 1.8 1.8 8.3 0.1 3.3 3 0 0 3 3 3 0 UTP15 C terminal RPM2 PF08579.11 CEG47129.1 - 0.093 13.1 0.7 0.52 10.7 0.4 2.5 2 1 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_12 PF13424.6 CEG47129.1 - 0.095 13.0 0.6 1.6 9.1 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat UCH PF00443.29 CEG47130.1 - 4.9e-36 124.5 0.1 7.9e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEG47130.1 - 2.6e-15 56.8 0.0 8.4e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 CEG47130.1 - 1.3e-05 25.0 0.2 3.5e-05 23.6 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 CEG47130.1 - 0.049 14.1 0.2 0.36 11.3 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain pair PKcGMP_CC PF16808.5 CEG47130.1 - 6.4 6.7 6.3 2.6 8.0 1.0 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase tRNA_bind PF01588.20 CEG47132.1 - 7.1e-19 67.7 0.2 1.1e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Rap1a PF18602.1 CEG47132.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Rap1a immunity proteins P34-Arc PF04045.14 CEG47133.1 - 7.4e-75 251.7 0.0 9e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PH PF00169.29 CEG47134.1 - 0.00021 21.7 0.0 0.00041 20.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DSPc PF00782.20 CEG47135.1 - 8.8e-30 103.2 0.1 2.5e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain FYVE PF01363.21 CEG47135.1 - 2e-09 37.5 11.9 5.1e-09 36.1 11.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger Rhodanese PF00581.20 CEG47135.1 - 1e-05 26.0 0.0 0.00021 21.8 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain Y_phosphatase PF00102.27 CEG47135.1 - 0.00017 21.2 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEG47135.1 - 0.014 15.5 0.3 0.055 13.6 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CEG47135.1 - 0.03 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family IBR PF01485.21 CEG47135.1 - 0.064 13.5 6.3 0.26 11.5 6.3 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CEG47135.1 - 0.54 10.5 12.5 0.14 12.4 8.6 2.1 2 1 0 2 2 2 0 FYVE-type zinc finger DSPc PF00782.20 CEG47137.1 - 1.2e-30 106.0 0.0 1.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEG47137.1 - 0.00057 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CEG47137.1 - 0.0064 17.0 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase2 PF03162.13 CEG47137.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family HupE_UreJ_2 PF13795.6 CEG47139.1 - 0.0042 16.8 4.6 0.032 13.9 0.7 2.7 2 1 1 3 3 3 1 HupE / UreJ protein VIT1 PF01988.19 CEG47139.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 VIT family MerE PF05052.12 CEG47139.1 - 0.13 12.2 3.7 0.44 10.5 3.7 1.9 1 0 0 1 1 1 0 MerE protein Nuc_sug_transp PF04142.15 CEG47140.1 - 9.1e-21 74.3 12.5 1.3e-20 73.9 12.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CEG47140.1 - 5.6e-07 29.1 19.3 1e-06 28.2 19.3 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 CEG47140.1 - 2 8.6 28.4 0.016 15.3 10.3 2.8 2 1 0 2 2 2 0 EamA-like transporter family DUF2070 PF09843.9 CEG47140.1 - 5.4 5.2 24.2 0.46 8.7 8.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) CobD_Cbib PF03186.13 CEG47141.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 CobD/Cbib protein RCC1 PF00415.18 CEG47146.1 - 2.1e-50 169.1 9.2 7.4e-11 42.5 0.1 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG47146.1 - 9.9e-36 120.8 30.7 1.7e-10 40.4 2.0 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat VPS9 PF02204.18 CEG47146.1 - 5.7e-06 26.5 3.0 0.001 19.2 0.3 2.6 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DUF2357 PF09823.9 CEG47146.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) RXLR PF16810.5 CEG47148.1 - 0.1 13.0 0.3 0.35 11.3 0.3 1.9 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Metallophos PF00149.28 CEG47149.1 - 1.5e-06 28.9 1.3 6.4e-05 23.5 1.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DDE_1 PF03184.19 CEG47150.1 - 1.3e-29 103.1 0.1 2.1e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CEG47150.1 - 2e-11 43.7 0.0 6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEG47150.1 - 0.034 13.8 0.6 0.11 12.2 0.6 1.9 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Ras PF00071.22 CEG47151.1 - 2.5e-55 186.5 0.0 3e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG47151.1 - 6.9e-33 113.4 0.0 1.3e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG47151.1 - 1.6e-14 53.7 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG47151.1 - 8.9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG47151.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG47151.1 - 0.00013 21.6 0.0 0.0036 16.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEG47151.1 - 0.00046 20.1 0.1 0.0041 17.0 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CEG47151.1 - 0.00089 19.5 0.0 0.0018 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG47151.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 CEG47151.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.19 CEG47151.1 - 0.015 14.9 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CEG47151.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CEG47151.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CEG47151.1 - 0.043 13.6 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CEG47151.1 - 0.047 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CEG47151.1 - 0.053 12.9 0.1 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 CEG47151.1 - 0.06 12.5 0.4 0.098 11.8 0.4 1.7 1 1 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 CEG47151.1 - 0.069 13.1 0.1 0.45 10.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CEG47151.1 - 0.079 12.9 0.2 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_L21e PF01157.18 CEG47152.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L21e ANAPC4_WD40 PF12894.7 CEG47153.1 - 1.2e-12 47.9 2.4 0.00023 21.4 0.1 5.6 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEG47153.1 - 0.0025 15.9 0.6 3.5 5.5 0.0 3.1 2 1 1 3 3 3 3 IKI3 family eIF2A PF08662.11 CEG47153.1 - 0.054 13.4 0.4 8.7 6.2 0.1 3.3 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A AAA PF00004.29 CEG47154.1 - 4.5e-45 153.3 0.1 2.8e-31 108.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG47154.1 - 2e-10 41.3 1.4 0.0023 18.3 0.0 3.8 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CEG47154.1 - 3e-08 34.0 2.5 0.049 13.9 0.1 4.4 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 CEG47154.1 - 3.3e-08 33.8 0.0 0.00034 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CEG47154.1 - 1.3e-06 28.3 0.1 0.076 12.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG47154.1 - 5.4e-06 26.5 0.3 0.0029 17.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CEG47154.1 - 1.1e-05 25.9 0.1 0.021 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 CEG47154.1 - 1.8e-05 24.4 0.0 5.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 CEG47154.1 - 2.6e-05 23.9 2.2 1.9 8.0 0.2 3.6 3 1 1 4 4 3 2 AAA domain TsaE PF02367.17 CEG47154.1 - 3.1e-05 24.0 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEG47154.1 - 3.8e-05 23.7 0.0 0.0064 16.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEG47154.1 - 3.9e-05 24.0 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 CEG47154.1 - 4.3e-05 22.9 0.3 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CEG47154.1 - 0.00012 21.5 2.0 0.032 13.6 0.3 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CEG47154.1 - 0.00022 20.6 0.1 0.36 10.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 CEG47154.1 - 0.00025 21.0 0.0 0.2 11.6 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 CEG47154.1 - 0.0003 20.7 0.1 0.33 10.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CEG47154.1 - 0.00065 19.5 0.0 0.32 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CEG47154.1 - 0.0007 19.4 0.3 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 CEG47154.1 - 0.00092 19.8 0.0 0.53 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CEG47154.1 - 0.00092 18.7 0.0 9.6 5.6 0.0 3.5 2 1 0 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 CEG47154.1 - 0.0015 18.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEG47154.1 - 0.0031 17.2 0.0 0.049 13.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 CEG47154.1 - 0.0083 16.6 0.0 3.5 8.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 CEG47154.1 - 0.0099 15.6 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEG47154.1 - 0.011 16.0 0.8 13 6.1 0.5 3.2 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.14 CEG47154.1 - 0.014 15.5 0.0 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_29 PF13555.6 CEG47154.1 - 0.017 14.8 0.0 0.52 10.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CEG47154.1 - 0.018 14.9 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 CEG47154.1 - 0.019 14.1 0.0 2.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 CEG47154.1 - 0.021 15.1 0.1 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CEG47154.1 - 0.022 14.6 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEG47154.1 - 0.023 14.2 0.1 5.4 6.5 0.1 2.9 2 1 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 CEG47154.1 - 0.032 14.3 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Torsin NB-ARC PF00931.22 CEG47154.1 - 0.037 13.2 0.2 6.2 5.9 0.1 2.7 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 CEG47154.1 - 0.04 14.0 0.5 7.1 6.7 0.1 2.7 3 0 0 3 3 2 0 Shikimate kinase Sigma54_activat PF00158.26 CEG47154.1 - 0.062 13.0 0.0 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 CEG47154.1 - 0.096 12.5 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEG47154.1 - 0.1 12.5 0.1 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Hydin_ADK PF17213.3 CEG47154.1 - 0.2 11.9 1.6 1.5 9.0 0.0 2.8 4 0 0 4 4 2 0 Hydin Adenylate kinase-like domain Ndc1_Nup PF09531.10 CEG47155.1 - 4.1e-12 45.6 0.4 4.1e-12 45.6 0.4 3.1 3 0 0 3 3 3 1 Nucleoporin protein Ndc1-Nup DUF1634 PF07843.11 CEG47155.1 - 0.28 11.3 2.4 0.95 9.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) TAP42 PF04177.12 CEG47156.1 - 9.9e-65 218.8 16.2 1.2e-64 218.5 16.2 1.0 1 0 0 1 1 1 1 TAP42-like family GPCR_chapero_1 PF11904.8 CEG47157.1 - 2.7e-34 119.0 18.3 4.9e-18 65.6 10.1 2.5 2 1 0 2 2 2 2 GPCR-chaperone Ank PF00023.30 CEG47157.1 - 4.4e-06 26.9 0.0 0.0071 16.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CEG47157.1 - 1.3e-05 25.7 0.1 0.00012 22.6 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47157.1 - 7.4e-05 23.2 0.3 0.021 15.4 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG47157.1 - 0.00027 21.2 0.0 0.62 10.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47157.1 - 0.013 16.0 0.0 0.7 10.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat DDE_Tnp_ISL3 PF01610.17 CEG47157.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Transposase MatE PF01554.18 CEG47160.1 - 3.1e-18 65.9 11.8 2.1e-13 50.2 0.6 3.2 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 CEG47160.1 - 2.9e-05 24.1 20.2 0.00079 19.5 0.9 3.2 2 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain SNF2_N PF00176.23 CEG47162.1 - 3.7e-46 157.5 0.1 8.5e-46 156.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG47162.1 - 1.4e-17 64.0 0.4 6.1e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CobA_CobO_BtuR PF02572.15 CEG47162.1 - 0.014 15.7 0.1 0.069 13.4 0.0 2.1 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ResIII PF04851.15 CEG47162.1 - 0.14 12.1 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Tudor-knot PF11717.8 CEG47163.1 - 4.7e-07 29.6 0.4 1.5e-06 28.0 0.4 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF775 PF05603.12 CEG47163.1 - 0.028 13.9 0.9 0.12 11.8 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ank_2 PF12796.7 CEG47165.1 - 2.9e-28 98.3 1.0 2.8e-13 50.3 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) ACBP PF00887.19 CEG47165.1 - 4.8e-22 78.0 0.3 8.4e-22 77.2 0.3 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.30 CEG47165.1 - 4.5e-17 61.7 1.0 3.2e-07 30.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CEG47165.1 - 3.3e-15 56.0 0.0 2.5e-08 34.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG47165.1 - 3.4e-13 49.8 0.1 8.6e-08 32.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47165.1 - 8.4e-11 41.1 0.1 0.0001 22.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat S-methyl_trans PF02574.16 CEG47166.1 - 5.7e-37 128.0 0.0 7.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CALM_bind PF16025.5 CEG47168.1 - 0.0008 19.8 1.5 0.00093 19.6 1.5 1.1 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding KH_8 PF17903.1 CEG47169.1 - 1.3e-32 111.7 0.1 2.1e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain VP_N-CPKC PF11475.8 CEG47173.1 - 1.9 8.5 3.1 90 3.1 0.0 3.5 4 0 0 4 4 4 0 Virion protein N terminal domain RXLR PF16810.5 CEG47174.1 - 0.017 15.6 0.2 0.028 14.8 0.2 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity cobW PF02492.19 CEG47175.1 - 4.8e-49 166.3 0.0 7.4e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEG47175.1 - 5.1e-17 61.6 0.1 1.1e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CEG47175.1 - 0.0011 18.9 0.2 1.6 8.6 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CEG47175.1 - 0.0019 18.7 1.5 0.49 10.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEG47175.1 - 0.0019 18.2 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CEG47175.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG47175.1 - 0.025 14.9 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CEG47175.1 - 0.05 13.9 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEG47175.1 - 0.082 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CEG47175.1 - 0.12 12.9 0.7 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Pkinase PF00069.25 CEG47176.1 - 7.6e-72 241.8 0.0 1.1e-71 241.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47176.1 - 6.4e-38 130.5 0.0 1.1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 CEG47176.1 - 2.1e-08 34.2 0.0 6e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 NAF domain Kinase-like PF14531.6 CEG47176.1 - 4.5e-08 32.8 0.0 9.3e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG47176.1 - 0.00047 19.6 0.1 0.0009 18.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG47176.1 - 0.0084 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEG47176.1 - 0.046 13.3 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase KA1 PF02149.19 CEG47176.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 DUF846 PF05832.12 CEG47177.1 - 1.6e-55 187.0 9.1 1.6e-55 187.0 9.1 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF846) Pribosyltran_N PF13793.6 CEG47177.1 - 1e-36 125.4 0.4 7.3e-36 122.6 0.2 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEG47177.1 - 3e-21 76.3 1.3 7.5e-21 75.0 1.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEG47177.1 - 4.4e-14 52.3 4.6 5.4e-11 42.3 0.2 3.0 3 1 0 3 3 3 2 Phosphoribosyl transferase domain SPA PF08616.10 CEG47177.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis DEAD PF00270.29 CEG47178.1 - 2.2e-12 47.1 0.0 6.3e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEG47178.1 - 0.001 19.1 0.9 0.015 15.3 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CEG47178.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IlvN PF07991.12 CEG47178.1 - 0.4 10.2 2.1 0.9 9.1 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain OPA3 PF07047.12 CEG47179.1 - 1.1e-32 112.5 0.1 1.7e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Caveolin PF01146.17 CEG47179.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Caveolin Retrotran_gag_2 PF14223.6 CEG47180.1 - 1.3e-13 50.8 0.1 1.6e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG47180.1 - 0.00034 20.6 3.1 0.0005 20.0 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG47180.1 - 0.0021 17.8 4.3 0.003 17.3 4.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEG47180.1 - 0.0048 16.6 2.6 0.0097 15.6 2.6 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger CLIP1_ZNF PF16641.5 CEG47180.1 - 0.0075 16.1 2.2 0.012 15.5 2.2 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle eIF3g PF12353.8 CEG47180.1 - 0.0097 16.3 0.5 0.015 15.7 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 CEG47180.1 - 0.0098 15.8 2.5 0.015 15.2 2.5 1.2 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.26 CEG47181.1 - 3.8e-11 43.2 0.0 9.8e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Podovirus_Gp16 PF05894.12 CEG47181.1 - 0.0059 16.1 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Podovirus DNA encapsidation protein (Gp16) RVT_2 PF07727.14 CEG47182.1 - 7.1e-10 38.9 0.1 8.4e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG47182.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF896 PF05979.12 CEG47183.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF4460 PF14687.6 CEG47187.1 - 9.4e-21 73.9 0.0 2.2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Pkinase_Tyr PF07714.17 CEG47188.1 - 1.8e-42 145.5 0.0 2.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG47188.1 - 4.4e-37 127.9 0.0 7.4e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CEG47188.1 - 0.00024 20.5 0.0 0.00057 19.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG47188.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 CEG47188.1 - 0.064 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4460 PF14687.6 CEG47189.1 - 1.2e-20 73.6 0.0 2.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF3543 PF12063.8 CEG47193.1 - 6.9e-15 55.1 1.9 3.7e-10 39.6 0.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3543) MIT PF04212.18 CEG47193.1 - 0.006 16.6 1.7 1.2 9.3 0.0 3.2 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Cyclin_N PF00134.23 CEG47194.1 - 5.2e-24 84.4 1.9 5.2e-24 84.4 1.9 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain SNF2_N PF00176.23 CEG47195.1 - 7.2e-54 182.8 0.1 5.8e-53 179.8 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG47195.1 - 8e-13 48.7 0.1 3.1e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG47195.1 - 0.00084 19.4 0.0 0.007 16.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ADH_N_2 PF16884.5 CEG47197.1 - 0.084 12.8 0.6 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Inhibitor_I68 PF10468.9 CEG47197.1 - 0.12 12.8 0.2 8.9 6.8 0.1 2.6 2 0 0 2 2 2 0 Carboxypeptidase inhibitor I68 peroxidase PF00141.23 CEG47198.1 - 3.3e-08 33.5 0.1 4e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Peroxidase RVT_2 PF07727.14 CEG47200.1 - 1e-18 67.9 0.1 1.3e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 CEG47200.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Chlororespiratory reduction 6 DUF4734 PF15881.5 CEG47204.1 - 0.032 14.4 0.6 0.038 14.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) PALP PF00291.25 CEG47205.1 - 2.8e-73 246.9 4.8 3.6e-73 246.5 4.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CEG47205.1 - 5.9e-34 115.7 0.5 2.2e-23 81.8 0.1 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GARS_N PF02844.15 CEG47205.1 - 0.064 14.0 0.6 0.21 12.4 0.2 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Sec5 PF15469.6 CEG47206.1 - 5.7e-17 62.1 0.8 5.7e-17 62.1 0.8 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 CEG47206.1 - 0.0011 19.1 3.1 0.0012 18.9 0.4 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Bestrophin PF01062.21 CEG47206.1 - 0.019 14.3 0.1 0.049 13.0 0.1 1.6 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AbiEii PF08843.11 CEG47206.1 - 0.053 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Baculo_PEP_C PF04513.12 CEG47206.1 - 0.057 13.5 4.8 4.5 7.3 1.9 3.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2294 PF10057.9 CEG47206.1 - 0.1 12.7 2.5 1.3 9.1 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) TIP120 PF08623.10 CEG47211.1 - 1.2e-48 165.1 10.2 3.6e-45 153.8 0.1 6.5 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 CEG47211.1 - 4.1e-27 91.9 17.3 0.0026 17.8 0.0 12.5 13 0 0 13 13 12 5 HEAT repeat HEAT_2 PF13646.6 CEG47211.1 - 5.2e-22 78.0 8.8 0.017 15.5 0.0 9.1 6 2 2 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 CEG47211.1 - 1.4e-17 63.8 7.7 0.027 15.0 0.0 9.2 9 0 0 9 9 8 5 HEAT-like repeat Cnd1 PF12717.7 CEG47211.1 - 4.3e-08 33.4 19.1 0.11 12.5 0.1 8.3 5 3 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CEG47211.1 - 1.6e-05 25.0 10.5 0.025 14.8 0.0 6.3 7 0 0 7 7 6 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 CEG47211.1 - 6.5e-05 22.6 11.4 0.18 11.3 0.2 6.3 5 1 1 7 7 7 2 CLASP N terminal RasGEF_N_2 PF14663.6 CEG47211.1 - 0.0012 19.2 12.9 33 4.9 0.2 7.4 8 0 0 8 8 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Tti2 PF10521.9 CEG47211.1 - 0.0031 17.1 7.2 1.4 8.4 0.2 5.6 3 2 2 6 6 6 1 Tti2 family Sec7_N PF12783.7 CEG47211.1 - 0.0032 17.4 6.0 20 5.1 0.0 6.6 5 2 1 7 7 7 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_UF PF18817.1 CEG47211.1 - 0.0037 17.5 0.1 0.014 15.6 0.1 2.1 1 0 0 1 1 1 1 Repeat of uncharacterized protein PH0542 DUF4042 PF13251.6 CEG47211.1 - 0.016 14.9 14.4 11 5.6 0.0 7.2 7 2 1 8 8 8 0 Domain of unknown function (DUF4042) TAF6_C PF07571.13 CEG47211.1 - 0.04 14.2 0.0 8.5 6.8 0.0 4.5 3 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Telomere_reg-2 PF10193.9 CEG47211.1 - 0.073 13.5 13.7 58 4.2 0.1 7.7 7 2 0 8 8 8 0 Telomere length regulation protein Mesd PF10185.9 CEG47212.1 - 5.7e-06 26.3 2.3 5.7e-06 26.3 2.3 2.0 2 1 0 2 2 2 1 Chaperone for wingless signalling and trafficking of LDL receptor ABC_tran PF00005.27 CEG47213.1 - 1.1e-45 155.5 0.3 3.1e-22 79.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CEG47213.1 - 4.8e-23 81.0 6.7 4.8e-23 81.0 6.7 3.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 CEG47213.1 - 4.2e-18 66.2 5.2 0.00042 20.2 0.1 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG47213.1 - 2.7e-09 36.8 8.2 0.0072 15.8 3.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CEG47213.1 - 4.8e-08 33.1 1.6 0.0079 15.9 0.0 4.1 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 CEG47213.1 - 9.3e-07 28.5 0.4 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CEG47213.1 - 1.3e-05 25.5 0.1 0.06 13.6 0.0 3.1 2 1 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CEG47213.1 - 1.9e-05 24.7 0.0 0.24 11.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CEG47213.1 - 3.5e-05 24.1 1.4 0.0022 18.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 CEG47213.1 - 0.00033 20.6 0.6 1.1 9.2 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_18 PF13238.6 CEG47213.1 - 0.0004 20.9 0.6 3 8.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CEG47213.1 - 0.00085 19.1 0.2 0.97 9.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CEG47213.1 - 0.0018 18.2 0.9 0.4 10.6 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 CEG47213.1 - 0.0019 18.7 0.4 0.023 15.2 0.0 4.9 5 1 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 CEG47213.1 - 0.0023 18.3 0.0 2.3 8.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF3584 PF12128.8 CEG47213.1 - 0.003 15.2 0.2 0.003 15.2 0.2 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) AAA_33 PF13671.6 CEG47213.1 - 0.0042 17.2 1.6 2.8 8.1 0.1 3.4 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CEG47213.1 - 0.01 15.0 0.0 1.2 8.3 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 CEG47213.1 - 0.01 16.2 0.9 0.61 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CEG47213.1 - 0.011 15.3 0.1 0.99 8.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CEG47213.1 - 0.011 15.6 0.3 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 CEG47213.1 - 0.014 15.4 0.3 4.6 7.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CEG47213.1 - 0.014 15.8 1.4 0.29 11.6 0.1 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CEG47213.1 - 0.02 14.2 0.4 4 6.7 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_14 PF13173.6 CEG47213.1 - 0.03 14.4 0.0 3.1 7.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain SbcCD_C PF13558.6 CEG47213.1 - 0.031 14.5 0.3 3.2 8.1 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 CEG47213.1 - 0.059 12.9 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.14 CEG47213.1 - 0.065 13.1 0.1 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 CEG47213.1 - 0.069 12.7 0.1 3.4 7.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CEG47213.1 - 0.069 12.9 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CEG47213.1 - 0.095 12.8 13.1 0.69 10.0 0.0 4.3 5 0 0 5 5 4 0 Helicase HerA, central domain TsaE PF02367.17 CEG47213.1 - 0.12 12.4 0.9 4.3 7.4 0.1 2.9 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NPV_P10 PF05531.12 CEG47213.1 - 0.14 12.7 0.9 2.2 8.8 0.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dynamin_N PF00350.23 CEG47213.1 - 0.15 12.1 9.8 0.51 10.4 0.1 4.2 4 1 1 5 5 5 0 Dynamin family MukB PF04310.12 CEG47213.1 - 0.18 11.6 1.2 6.3 6.5 0.1 2.8 3 0 0 3 3 2 0 MukB N-terminal AAA_30 PF13604.6 CEG47213.1 - 0.66 9.7 10.6 0.66 9.7 0.6 4.0 4 1 0 4 4 3 0 AAA domain RecG_N PF17190.4 CEG47213.1 - 1.2 9.9 6.4 3.8 8.3 0.2 3.1 2 1 0 2 2 2 0 RecG N-terminal helical domain MeaB PF03308.16 CEG47213.1 - 1.6 7.7 3.9 10 5.0 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 CEG47213.1 - 2 7.0 0.0 2 7.0 0.0 5.3 4 2 1 5 5 5 0 AAA domain Pox_A32 PF04665.12 CEG47213.1 - 5.8 6.3 6.5 7.7 5.9 0.1 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein Snf7 PF03357.21 CEG47214.1 - 6e-43 146.4 7.2 7.1e-43 146.2 7.2 1.0 1 0 0 1 1 1 1 Snf7 YlqD PF11068.8 CEG47214.1 - 0.021 15.2 3.4 0.021 15.2 3.4 2.1 1 1 1 2 2 2 0 YlqD protein SpoIISA_toxin PF14171.6 CEG47214.1 - 0.047 13.4 0.7 0.07 12.8 0.4 1.4 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF812 PF05667.11 CEG47214.1 - 0.088 11.7 13.2 0.78 8.6 10.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4094 PF13334.6 CEG47214.1 - 0.09 13.2 0.9 5.1 7.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) SurA_N_2 PF13623.6 CEG47214.1 - 0.1 12.4 3.3 0.094 12.6 1.6 1.8 1 1 1 2 2 2 0 SurA N-terminal domain TSC22 PF01166.18 CEG47214.1 - 0.11 12.8 1.3 18 5.7 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 CEG47214.1 - 0.36 11.1 16.0 1.3 9.4 0.6 3.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain Spc7 PF08317.11 CEG47214.1 - 0.68 8.8 11.6 0.35 9.7 9.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 CEG47214.1 - 0.93 10.0 10.0 6 7.4 2.9 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phe_tRNA-synt_N PF02912.18 CEG47214.1 - 1.3 9.0 8.7 0.074 13.0 2.5 2.2 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Swi5 PF07061.11 CEG47214.1 - 1.8 8.7 11.8 1.6e+02 2.5 7.7 3.2 2 1 0 2 2 2 0 Swi5 DUF1664 PF07889.12 CEG47214.1 - 2.2 8.4 9.1 5.8 7.0 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YgaB PF14182.6 CEG47214.1 - 2.6 8.5 10.4 0.88 10.0 0.2 3.2 2 2 1 3 3 3 0 YgaB-like protein Latarcin PF10279.9 CEG47214.1 - 2.9 8.4 6.9 1.3 9.5 2.3 2.4 2 1 0 2 2 2 0 Latarcin precursor Nup88 PF10168.9 CEG47214.1 - 2.9 5.6 8.7 3.8 5.2 8.7 1.2 1 0 0 1 1 1 0 Nuclear pore component EIN3 PF04873.13 CEG47214.1 - 3.4 6.9 6.4 32 3.7 6.4 2.0 1 1 0 1 1 1 0 Ethylene insensitive 3 PRKG1_interact PF15898.5 CEG47214.1 - 5 8.1 10.7 6.8 7.6 5.2 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Prefoldin PF02996.17 CEG47214.1 - 7.9 6.4 14.0 5.3 7.0 0.8 3.5 2 1 1 4 4 3 0 Prefoldin subunit DDE_1 PF03184.19 CEG47216.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP_synth_reg PF14960.6 CEG47218.1 - 0.036 13.6 0.2 0.054 13.0 0.2 1.2 1 0 0 1 1 1 0 ATP synthase regulation PDEase_I PF00233.19 CEG47219.1 - 4.4e-70 236.1 2.4 4.7e-70 236.0 0.1 2.1 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CEG47219.1 - 0.023 14.9 0.2 0.059 13.6 0.2 1.7 1 0 0 1 1 1 0 HD domain Ribosomal_L36e PF01158.18 CEG47220.1 - 2.7e-35 120.5 2.2 3.5e-35 120.1 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e ENT PF03735.14 CEG47220.1 - 0.037 14.1 0.6 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 ENT domain PGK PF00162.19 CEG47224.1 - 7.7e-159 528.7 0.2 8.9e-159 528.4 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PIN_10 PF18478.1 CEG47224.1 - 0.064 13.5 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 PIN like domain PHC2_SAM_assoc PF16616.5 CEG47225.1 - 0.015 16.1 4.7 0.015 16.1 4.7 2.1 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Gram_pos_anchor PF00746.21 CEG47225.1 - 0.029 14.3 0.8 0.063 13.2 0.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Chordopox_A13L PF05961.11 CEG47225.1 - 0.09 13.0 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Phage_TTP_13 PF16463.5 CEG47225.1 - 0.15 11.6 0.3 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Phage tail tube protein family Pkinase PF00069.25 CEG47229.1 - 1.2e-61 208.3 0.0 1.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47229.1 - 1.7e-43 148.8 0.0 2.2e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG47229.1 - 7.2e-06 25.5 0.0 4.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEG47229.1 - 0.00026 19.9 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG47229.1 - 0.056 13.4 0.3 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEG47229.1 - 0.16 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain VPS9 PF02204.18 CEG47230.1 - 1.4e-12 47.7 0.2 4.1e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Atg14 PF10186.9 CEG47230.1 - 0.0022 17.2 3.0 0.0046 16.1 3.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 adh_short PF00106.25 CEG47231.1 - 3.4e-37 127.8 0.0 4.6e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG47231.1 - 1e-22 80.9 0.0 1.4e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG47231.1 - 7.5e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CEG47231.1 - 0.00026 20.5 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEG47231.1 - 0.00097 18.7 0.0 0.055 12.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEG47231.1 - 0.0066 15.6 0.2 0.012 14.7 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CEG47231.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding PUFD PF16553.5 CEG47231.1 - 0.072 13.2 0.2 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain YwiC PF14256.6 CEG47232.1 - 0.042 14.2 10.0 0.24 11.7 9.1 2.3 1 1 1 2 2 2 0 YwiC-like protein Arteri_Gl PF00951.18 CEG47232.1 - 1.8 8.3 8.1 0.18 11.6 0.7 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF1129 PF06570.11 CEG47232.1 - 7.7 5.9 7.3 1.5e+02 1.7 6.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) T2SSF PF00482.23 CEG47233.1 - 0.47 10.4 2.8 0.67 9.9 2.8 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F NPBW PF15180.6 CEG47234.1 - 0.38 10.6 4.2 0.69 9.8 1.3 2.5 1 1 2 3 3 3 0 Neuropeptides B and W Asp_protease_2 PF13650.6 CEG47235.1 - 0.00021 21.8 0.0 0.00026 21.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG47235.1 - 0.018 15.6 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CEG47236.1 - 5.6e-12 45.6 0.8 8.5e-12 45.0 0.8 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain YajC PF02699.15 CEG47238.1 - 0.024 14.5 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit CutA1 PF03091.15 CEG47239.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein IL15 PF02372.15 CEG47239.1 - 0.13 12.3 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Interleukin 15 Tubulin PF00091.25 CEG47241.1 - 6.6e-68 228.8 0.0 1.1e-67 228.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEG47241.1 - 4.6e-41 139.9 0.2 7.4e-41 139.3 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEG47241.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CEG47241.1 - 0.0014 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CEG47241.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Hydrolase_6 PF13344.6 CEG47245.1 - 9.3e-25 86.7 0.0 4.7e-24 84.4 0.0 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG47245.1 - 3.6e-17 62.2 0.0 6.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CEG47245.1 - 8.1e-07 29.3 0.4 0.047 13.8 0.0 3.3 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEG47245.1 - 0.0001 22.7 0.1 2.7 8.2 0.0 3.8 2 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase Importin_rep_5 PF18816.1 CEG47245.1 - 0.16 12.3 0.1 7.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Importin repeat zf-RING_9 PF13901.6 CEG47246.1 - 0.0019 18.2 1.7 0.0019 18.2 1.7 2.3 3 0 0 3 3 3 1 Putative zinc-RING and/or ribbon zf-HC5HC2H PF13771.6 CEG47246.1 - 0.0028 17.8 3.3 0.0028 17.8 3.3 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 CEG47246.1 - 0.013 15.4 8.9 0.013 15.4 8.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CEG47246.1 - 0.043 14.0 2.8 0.13 12.4 2.8 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 CEG47246.1 - 0.26 10.9 4.3 0.63 9.7 4.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 CEG47246.1 - 7 6.7 17.0 0.036 14.0 6.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 CEG47246.1 - 8 6.4 18.0 0.028 14.3 4.9 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Oxidored_molyb PF00174.19 CEG47248.1 - 4.9e-59 198.8 0.0 8.9e-59 197.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CEG47248.1 - 1.2e-42 145.2 0.5 3e-42 143.9 0.5 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 CEG47248.1 - 2.2e-14 53.3 0.1 4.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIF3 PF01784.18 CEG47248.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Utp11 PF03998.13 CEG47249.1 - 4.9e-70 236.3 26.1 5.5e-70 236.1 26.1 1.0 1 0 0 1 1 1 1 Utp11 protein SWIM PF04434.17 CEG47253.1 - 0.0021 17.7 0.4 0.0044 16.6 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger SesA PF17107.5 CEG47254.1 - 0.011 15.9 1.6 0.088 13.0 1.6 2.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Cep57_MT_bd PF06657.13 CEG47254.1 - 0.034 14.6 1.4 0.066 13.7 1.4 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 RICTOR_M PF14666.6 CEG47254.1 - 0.053 13.3 0.5 2.6 7.9 0.0 2.9 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Bac_small_YrzI PF09501.10 CEG47254.1 - 0.27 11.4 2.8 2.8 8.2 0.1 2.9 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Ca_bind_SSO6904 PF18249.1 CEG47254.1 - 0.28 11.6 4.3 1.6 9.1 1.2 3.0 2 1 1 3 3 3 0 Calcium binding protein SSO6904 putAbiC PF16872.5 CEG47254.1 - 0.29 11.8 4.0 29 5.4 0.3 3.9 3 2 1 4 4 4 0 Putative phage abortive infection protein Sec1 PF00995.23 CEG47256.1 - 1.6e-106 357.8 0.0 1.9e-106 357.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1985 PF09331.11 CEG47256.1 - 0.14 12.1 0.1 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) GTP_EFTU PF00009.27 CEG47257.1 - 1.1e-31 109.9 2.0 2.6e-31 108.7 1.9 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEG47257.1 - 1.1e-16 60.9 0.9 3e-16 59.4 0.9 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CEG47257.1 - 7.3e-10 38.9 0.0 1.9e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG47257.1 - 3.4e-08 33.6 1.6 0.00016 21.6 0.3 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CEG47257.1 - 5e-06 26.5 0.1 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CEG47257.1 - 6.6e-06 25.7 0.2 2.4e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CEG47257.1 - 2.8e-05 23.9 0.6 8.2e-05 22.4 0.6 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CEG47257.1 - 0.00019 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 CEG47257.1 - 0.00085 19.2 0.2 0.017 14.9 0.1 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.22 CEG47257.1 - 0.002 17.8 0.1 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG47257.1 - 0.0027 17.9 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEG47257.1 - 0.0067 16.0 0.2 1.2 8.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CEG47257.1 - 0.0088 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CEG47257.1 - 0.02 15.4 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CEG47257.1 - 0.03 14.6 1.0 0.098 12.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CEG47257.1 - 0.041 13.9 0.6 0.23 11.5 0.0 2.4 2 1 1 3 3 3 0 Dynamin family Mito_carr PF00153.27 CEG47258.1 - 1.3e-55 185.3 2.1 4.4e-18 65.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein V_ATPase_I PF01496.19 CEG47259.1 - 0.31 8.9 15.1 0.4 8.5 15.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.6 CEG47259.1 - 3 8.0 26.3 0.37 10.9 5.5 4.4 2 1 3 5 5 5 0 Centrosome localisation domain of PPC89 Elicitin PF00964.17 CEG47260.1 - 1.7e-15 56.9 6.1 2.7e-15 56.3 6.1 1.3 1 0 0 1 1 1 1 Elicitin RCC1 PF00415.18 CEG47261.1 - 1.3e-65 217.8 16.6 2.7e-10 40.7 0.2 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG47261.1 - 3.5e-40 135.0 41.2 2.5e-08 33.5 2.1 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DUF4498 PF14926.6 CEG47263.1 - 3.2e-62 210.0 0.0 3.7e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) zf-HIT PF04438.16 CEG47264.1 - 7.2e-10 38.6 13.2 7.2e-10 38.6 13.2 1.9 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 CEG47264.1 - 0.0012 18.5 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF5420 PF17457.2 CEG47264.1 - 0.058 13.3 1.2 0.47 10.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5420) zf-MYND PF01753.18 CEG47264.1 - 0.17 12.0 13.5 0.37 10.9 13.5 1.5 1 0 0 1 1 1 0 MYND finger PH_3 PF14593.6 CEG47265.1 - 5.5e-09 36.1 1.1 8.7e-06 25.8 0.2 2.4 1 1 1 2 2 2 2 PH domain PH PF00169.29 CEG47265.1 - 9.6e-08 32.5 0.1 4.8e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 PH domain PDZ_6 PF17820.1 CEG47265.1 - 1.2e-07 31.5 0.2 0.0017 18.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CEG47265.1 - 2.2e-07 31.1 0.6 0.00021 21.6 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CEG47265.1 - 0.0048 17.2 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 CEG47265.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain SANTA PF09133.10 CEG47267.1 - 5.4e-06 26.8 0.2 0.00019 21.8 0.0 2.7 2 0 0 2 2 2 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 CEG47267.1 - 0.00052 20.2 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain IHABP4_N PF16174.5 CEG47267.1 - 0.0043 17.7 7.6 0.0043 17.7 7.6 3.2 3 1 1 4 4 4 1 Intracellular hyaluronan-binding protein 4 N-terminal Myb_DNA-bind_6 PF13921.6 CEG47267.1 - 0.02 15.1 0.2 0.049 13.9 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain S1FA PF04689.13 CEG47267.1 - 1.9 8.7 4.3 5.4 7.2 2.4 2.7 2 0 0 2 2 2 0 DNA binding protein S1FA Esterase PF00756.20 CEG47268.1 - 5.3e-50 170.4 0.0 6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CEG47268.1 - 0.00082 18.7 0.1 0.0021 17.3 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CEG47268.1 - 0.005 16.3 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CEG47268.1 - 0.075 11.9 0.0 0.17 10.8 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme LCAT PF02450.15 CEG47269.1 - 1.1e-68 232.2 0.0 1.5e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 CEG47269.1 - 0.015 14.8 0.1 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CEG47269.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Aconitase PF00330.20 CEG47275.1 - 1.3e-72 245.3 0.1 1.1e-70 239.0 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEG47275.1 - 8.1e-17 61.8 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain AAA_18 PF13238.6 CEG47276.1 - 4.1e-30 105.0 0.1 6e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CEG47276.1 - 1.5e-07 31.9 0.8 1.8e-06 28.4 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 CEG47276.1 - 4.8e-06 26.9 0.2 3.7e-05 24.0 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 CEG47276.1 - 1.3e-05 25.6 0.0 9.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEG47276.1 - 4.4e-05 23.7 0.4 0.065 13.4 0.1 2.5 2 1 0 2 2 2 2 AAA domain ADK PF00406.22 CEG47276.1 - 0.00042 20.5 0.6 0.031 14.4 0.1 2.3 1 1 0 2 2 2 1 Adenylate kinase AAA_16 PF13191.6 CEG47276.1 - 0.00045 20.7 0.0 0.00083 19.8 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain dNK PF01712.19 CEG47276.1 - 0.00051 20.0 0.7 0.069 13.0 0.2 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_24 PF13479.6 CEG47276.1 - 0.00084 19.1 0.1 0.0058 16.4 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEG47276.1 - 0.0011 19.2 0.1 0.0047 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CEG47276.1 - 0.0012 18.8 0.3 0.0024 17.8 0.0 1.7 2 1 0 2 2 2 1 NTPase ATPase PF06745.13 CEG47276.1 - 0.0018 17.7 0.4 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 KaiC Viral_helicase1 PF01443.18 CEG47276.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEG47276.1 - 0.0075 16.6 0.2 0.0085 16.4 0.2 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CEG47276.1 - 0.017 14.8 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 CEG47276.1 - 0.019 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEG47276.1 - 0.025 14.1 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_32 PF13654.6 CEG47276.1 - 0.026 13.3 0.2 0.58 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CEG47276.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 CEG47276.1 - 0.033 13.4 0.1 0.07 12.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 CEG47276.1 - 0.036 13.8 0.6 0.093 12.5 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CEG47276.1 - 0.038 14.4 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 CEG47276.1 - 0.043 13.6 0.1 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 CEG47276.1 - 0.053 13.2 0.3 9.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase KTI12 PF08433.10 CEG47276.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SRPRB PF09439.10 CEG47276.1 - 0.073 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pyr_excise PF03013.14 CEG47276.1 - 0.083 12.9 0.7 3.5 7.6 0.1 2.3 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase FtsK_SpoIIIE PF01580.18 CEG47276.1 - 0.086 12.2 0.5 0.21 10.9 0.2 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family TniB PF05621.11 CEG47276.1 - 0.09 12.2 0.1 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 CEG47276.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEG47276.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Neuregulin PF02158.15 CEG47277.1 - 8.3 5.7 10.1 0.82 9.0 5.6 1.5 2 0 0 2 2 2 0 Neuregulin intracellular region Abhydrolase_1 PF00561.20 CEG47281.1 - 2.4e-17 63.4 0.1 2.6e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG47281.1 - 3e-14 52.9 0.0 6.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG47281.1 - 8e-12 46.2 0.2 1.4e-11 45.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CEG47281.1 - 0.0019 18.1 0.0 0.0059 16.5 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 CEG47281.1 - 0.011 14.5 0.0 0.025 13.3 0.0 1.5 1 0 0 1 1 1 0 Ndr family Chlorophyllase2 PF12740.7 CEG47281.1 - 0.011 14.7 0.0 0.06 12.2 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF915 PF06028.11 CEG47281.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 CEG47281.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family K-box PF01486.17 CEG47281.1 - 0.068 13.4 0.1 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 K-box region VASt PF16016.5 CEG47283.1 - 2.8e-30 105.8 0.8 7.1e-30 104.4 0.0 2.1 2 1 1 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CEG47283.1 - 4.1e-13 49.2 0.5 8.1e-13 48.3 0.5 1.5 1 0 0 1 1 1 1 GRAM domain DUF948 PF06103.11 CEG47283.1 - 0.22 11.8 0.6 0.52 10.6 0.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2 PF00152.20 CEG47285.1 - 4e-70 236.4 0.0 5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEG47285.1 - 8.6e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CEG47285.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEG47285.1 - 0.012 15.1 0.3 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF3019 PF11456.8 CEG47289.1 - 0.021 15.3 2.0 0.021 15.3 2.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3019) YadA_anchor PF03895.15 CEG47292.1 - 3.6e-11 43.0 2.3 5.5e-11 42.4 0.9 2.2 2 0 0 2 2 2 1 YadA-like membrane anchor domain Collagen PF01391.18 CEG47292.1 - 4.2e-10 39.2 28.2 1.5e-07 31.1 28.2 2.3 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Alanine_zipper PF11839.8 CEG47292.1 - 0.0079 16.5 7.4 0.0079 16.5 7.4 2.7 3 1 0 3 3 3 1 Alanine-zipper, major outer membrane lipoprotein UCH_C PF18031.1 CEG47294.1 - 2 8.4 6.2 2 8.4 2.3 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases 4HBT PF03061.22 CEG47299.1 - 7.7e-21 74.2 1.5 1.4e-11 44.6 0.4 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 CEG47299.1 - 0.00049 19.7 0.3 0.075 12.6 0.0 2.3 2 0 0 2 2 2 2 MaoC like domain M16C_assoc PF08367.11 CEG47299.1 - 0.032 13.4 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase M16C associated MutL_C PF08676.11 CEG47300.1 - 7.3e-29 100.4 0.1 1.9e-28 99.0 0.1 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CEG47300.1 - 5e-19 68.1 0.0 1.1e-17 63.8 0.0 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEG47300.1 - 6.2e-10 39.0 0.1 1.7e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEG47300.1 - 3.3e-08 34.0 0.0 6.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CRAL_TRIO PF00650.20 CEG47301.1 - 9.1e-30 103.5 0.1 1.5e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain FYVE PF01363.21 CEG47301.1 - 1.1e-08 35.1 0.4 2.4e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger CRAL_TRIO_2 PF13716.6 CEG47301.1 - 0.003 17.7 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Isochorismatase PF00857.20 CEG47303.1 - 1.4e-08 35.1 0.0 1.8e-05 25.0 0.0 2.7 1 1 1 2 2 2 2 Isochorismatase family RCC1 PF00415.18 CEG47305.1 - 1.7e-34 118.2 9.0 1e-09 38.8 0.1 7.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEG47305.1 - 3.8e-28 96.6 12.1 9e-08 31.7 0.1 6.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 CEG47305.1 - 1.2e-12 47.7 5.8 0.00028 20.9 0.0 6.0 6 1 0 6 6 6 2 IPT/TIG domain Astacin PF01400.24 CEG47306.1 - 3.9e-23 82.0 0.1 6.2e-22 78.1 0.1 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.6 CEG47306.1 - 0.0061 17.1 1.1 0.02 15.4 0.5 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CEG47306.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 CEG47306.1 - 0.047 13.5 0.2 0.083 12.7 0.2 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CEG47306.1 - 0.052 13.7 0.2 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEG47306.1 - 0.081 12.6 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CEG47306.1 - 0.14 11.0 0.3 0.2 10.5 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CEG47306.1 - 0.34 9.5 2.5 0.52 8.8 2.5 1.2 1 0 0 1 1 1 0 Putative peptidase family HAD PF12710.7 CEG47307.1 - 1.3e-08 35.5 0.1 8e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTH_Tnp_4 PF13613.6 CEG47311.1 - 0.0052 16.5 0.1 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease Acetyltransf_1 PF00583.25 CEG47313.1 - 2.1e-11 44.1 0.1 2.7e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG47313.1 - 3.7e-06 26.9 0.1 4.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG47313.1 - 8e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CEG47313.1 - 0.00011 22.5 0.2 0.00018 21.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEG47313.1 - 0.0038 17.3 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CEG47313.1 - 0.0046 17.1 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEG47313.1 - 0.025 14.7 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0029 PF01205.19 CEG47314.1 - 6.2e-05 23.3 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 LMBR1 PF04791.16 CEG47315.1 - 2.9e-45 155.2 32.0 3.5e-30 105.4 8.6 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein RPA PF10134.9 CEG47315.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Replication initiator protein A Jacalin PF01419.17 CEG47316.1 - 0.00028 20.8 0.5 0.00063 19.7 0.1 1.8 2 1 0 2 2 2 1 Jacalin-like lectin domain Csd3_N PF18059.1 CEG47319.1 - 0.075 13.6 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Csd3 N-terminal Pox_A32 PF04665.12 CEG47321.1 - 8.8e-05 22.1 0.7 0.00053 19.5 0.7 1.8 1 1 0 1 1 1 1 Poxvirus A32 protein Pesticin PF16754.5 CEG47321.1 - 0.046 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term CBM60 PF16841.5 CEG47322.1 - 0.068 13.6 0.3 0.16 12.4 0.1 1.6 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding DUF916 PF06030.12 CEG47322.1 - 0.12 12.4 0.3 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) CBP4 PF07960.11 CEG47323.1 - 0.035 14.0 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 CBP4 Sugar_tr PF00083.24 CEG47324.1 - 4e-43 147.9 25.6 1.5e-28 99.9 2.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEG47324.1 - 6.1e-30 104.3 53.3 5e-27 94.7 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 CEG47324.1 - 0.00072 17.9 1.2 0.002 16.4 0.5 2.0 2 0 0 2 2 2 1 BT1 family FTR1 PF03239.14 CEG47324.1 - 0.0018 17.5 5.0 0.0049 16.1 5.0 1.8 1 0 0 1 1 1 1 Iron permease FTR1 family MFS_1_like PF12832.7 CEG47324.1 - 1.7 7.4 16.4 0.35 9.7 7.5 2.9 2 1 1 3 3 3 0 MFS_1 like family Peptidase_M24 PF00557.24 CEG47327.1 - 1.8e-19 70.2 0.0 2.2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med26 PF08711.11 CEG47329.1 - 1.4e-24 85.8 13.1 6.8e-11 42.0 0.1 3.9 3 0 0 3 3 3 3 TFIIS helical bundle-like domain DEK_C PF08766.11 CEG47329.1 - 5.5e-10 39.0 0.1 1.9e-09 37.3 0.1 2.0 1 0 0 1 1 1 1 DEK C terminal domain Pescadillo_N PF06732.11 CEG47330.1 - 1.6e-115 385.3 0.9 1.6e-115 385.3 0.9 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CEG47330.1 - 1e-07 32.3 0.0 3e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PEX11 PF05648.14 CEG47330.1 - 2.2 7.7 0.0 2.2 7.7 0.0 3.7 4 1 0 4 4 4 0 Peroxisomal biogenesis factor 11 (PEX11) HA2 PF04408.23 CEG47331.1 - 2.2e-22 79.4 0.0 2.2e-22 79.4 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEG47331.1 - 2.2e-20 72.8 0.0 6.8e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEG47331.1 - 1.8e-10 41.1 0.5 2.2e-09 37.6 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEG47331.1 - 2.9e-08 33.7 0.0 1.1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEG47331.1 - 0.00014 22.1 0.5 0.0017 18.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEG47331.1 - 0.02 15.2 0.8 0.18 12.1 0.0 3.0 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 CEG47331.1 - 0.021 13.9 0.1 0.021 13.9 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 CEG47331.1 - 0.03 13.7 0.2 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 CEG47331.1 - 0.21 12.1 6.7 9.3 6.8 0.0 4.5 4 1 0 4 4 4 0 ABC transporter DUF678 PF05077.12 CEG47331.1 - 4.2 7.6 5.4 4.3 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) His_Phos_1 PF00300.22 CEG47333.1 - 0.014 15.1 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Acetyltransf_6 PF13480.7 CEG47335.1 - 0.11 12.7 1.1 0.14 12.3 1.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NYD-SP28_assoc PF14775.6 CEG47335.1 - 0.47 10.6 6.7 4.1 7.6 0.5 2.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 CEG47335.1 - 0.54 10.4 3.8 11 6.2 0.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper BT1 PF03092.16 CEG47336.1 - 0.0005 18.4 4.5 0.0005 18.4 4.5 2.5 2 1 0 2 2 2 2 BT1 family Gate PF07670.14 CEG47336.1 - 0.02 15.1 1.6 0.49 10.7 0.0 3.2 2 1 1 3 3 3 0 Nucleoside recognition Adeno_52K PF03052.15 CEG47336.1 - 0.23 10.9 0.1 0.36 10.2 0.1 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa MLTD_N PF06474.12 CEG47336.1 - 5.2 7.3 5.1 1 9.6 0.8 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif PDZ PF00595.24 CEG47337.1 - 3.1e-06 27.4 0.0 4.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG47337.1 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF2460 PF09343.10 CEG47337.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) F-box-like PF12937.7 CEG47339.1 - 2.7e-06 27.2 0.1 6.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like YdjC PF04794.12 CEG47339.1 - 0.0029 17.6 0.0 0.0044 17.0 0.1 1.5 2 0 0 2 2 2 1 YdjC-like protein F-box PF00646.33 CEG47339.1 - 0.023 14.6 0.2 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 F-box domain CemA PF03040.14 CEG47339.1 - 0.044 13.7 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 CemA family VLPT PF07122.11 CEG47339.1 - 0.052 13.3 2.5 0.094 12.5 2.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Acetyltransf_15 PF17013.5 CEG47339.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase Mannosyl_trans3 PF11051.8 CEG47340.1 - 0.0042 16.5 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CHORD PF04968.12 CEG47342.1 - 5.1e-30 104.0 13.9 9.7e-22 77.5 4.8 2.2 2 0 0 2 2 2 2 CHORD BTK PF00779.19 CEG47342.1 - 0.41 10.5 9.2 0.53 10.2 0.2 2.9 3 0 0 3 3 3 0 BTK motif ADH_zinc_N PF00107.26 CEG47343.1 - 5.4e-11 42.6 0.0 6.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEG47343.1 - 5.9e-09 37.1 0.0 6.8e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 CEG47344.1 - 4.9e-66 222.8 0.0 6.5e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47344.1 - 8.9e-48 162.8 0.0 1.3e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG47344.1 - 0.00047 19.0 0.0 0.00047 19.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG47344.1 - 0.0043 17.0 0.1 0.0088 16.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4094 PF13334.6 CEG47344.1 - 0.028 14.8 0.1 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SRP19 PF01922.17 CEG47347.1 - 0.049 14.6 0.0 0.07 14.1 0.0 1.3 1 0 0 1 1 1 0 SRP19 protein DUF5515 PF17635.2 CEG47348.1 - 0.11 13.2 0.0 0.12 13.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5515) Pterin_bind PF00809.22 CEG47349.1 - 3.8e-84 282.2 0.1 6e-84 281.5 0.1 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CEG47349.1 - 3.6e-33 114.4 0.0 2.7e-32 111.6 0.0 2.3 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MIF4G_like PF09088.11 CEG47349.1 - 0.073 12.8 0.4 0.28 10.9 0.0 2.0 3 0 0 3 3 3 0 MIF4G like P22_AR_N PF10547.9 CEG47350.1 - 0.07 13.5 0.0 0.084 13.2 0.0 1.0 1 0 0 1 1 1 0 P22_AR N-terminal domain dsrm PF00035.26 CEG47352.1 - 3.7e-05 24.3 8.9 0.0072 17.0 0.0 2.9 3 0 0 3 3 3 2 Double-stranded RNA binding motif TPR_19 PF14559.6 CEG47352.1 - 0.00055 20.4 0.6 0.00055 20.4 0.6 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG47352.1 - 0.53 10.5 6.0 0.45 10.7 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 CEG47354.1 - 4.3e-15 56.3 0.0 2.2e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEG47354.1 - 0.00048 20.2 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG47354.1 - 0.00066 20.1 0.0 0.0037 17.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEG47354.1 - 0.0039 17.4 0.2 0.026 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEG47354.1 - 0.0075 16.6 0.0 0.62 10.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 CEG47354.1 - 0.013 15.4 0.1 0.68 9.8 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea YcbB PF08664.10 CEG47354.1 - 0.029 14.4 1.3 0.45 10.6 0.1 2.8 2 0 0 2 2 2 0 YcbB domain TsaE PF02367.17 CEG47354.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CEG47354.1 - 0.045 14.0 0.0 0.23 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEG47354.1 - 0.047 13.3 0.3 0.26 10.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 CEG47354.1 - 0.097 12.7 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEG47354.1 - 0.14 11.9 0.1 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IQ PF00612.27 CEG47354.1 - 0.16 11.8 0.1 0.49 10.3 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif LRR_8 PF13855.6 CEG47355.1 - 1.4e-22 79.2 40.1 2.5e-08 33.6 5.1 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CEG47355.1 - 2.3e-14 53.3 22.8 0.00024 21.4 4.5 6.3 2 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG47355.1 - 1.7e-05 24.7 13.9 3.1 8.7 0.3 8.2 7 1 0 7 7 7 2 Leucine Rich Repeat WW PF00397.26 CEG47355.1 - 0.021 14.9 0.9 0.045 13.8 0.9 1.6 1 0 0 1 1 1 0 WW domain DUF2457 PF10446.9 CEG47355.1 - 2 7.5 22.2 4.5 6.3 22.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CEG47355.1 - 2.6 7.3 14.0 5.7 6.2 14.0 1.5 1 0 0 1 1 1 0 NOA36 protein MMR_HSR1 PF01926.23 CEG47356.1 - 9.4e-17 61.1 0.0 3.2e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG47356.1 - 2.6e-06 27.4 0.3 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CEG47356.1 - 1.4e-05 25.3 0.7 0.00085 19.4 0.1 2.9 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 CEG47356.1 - 6.8e-05 22.4 0.1 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEG47356.1 - 0.0012 18.4 0.9 0.19 11.2 0.1 3.1 4 1 0 4 4 4 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CEG47356.1 - 0.1 13.1 0.4 0.26 11.8 0.1 1.8 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 CEG47356.1 - 0.12 11.8 1.5 0.25 10.7 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Peptidase_M14 PF00246.24 CEG47357.1 - 1.6e-12 47.9 0.0 6.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CEG47357.1 - 2.6e-11 43.8 0.1 5.9e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain CDT1 PF08839.11 CEG47357.1 - 0.022 15.1 0.1 0.087 13.1 0.0 2.0 2 0 0 2 2 2 0 DNA replication factor CDT1 like FliD_N PF02465.18 CEG47357.1 - 0.72 10.6 5.0 0.33 11.7 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RGS PF00615.19 CEG47358.1 - 0.12 12.7 0.3 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Regulator of G protein signaling domain Sel1 PF08238.12 CEG47359.1 - 1.8e-27 95.2 8.0 6.7e-08 33.0 0.4 4.2 4 0 0 4 4 4 4 Sel1 repeat TPR_19 PF14559.6 CEG47359.1 - 0.016 15.7 1.5 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CEG47359.1 - 2.8 8.1 5.4 49 4.1 0.2 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PI3_PI4_kinase PF00454.27 CEG47360.1 - 1e-31 110.7 0.2 2e-30 106.5 0.2 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 CEG47360.1 - 1.9e-14 54.0 0.0 4.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PI3Ka PF00613.20 CEG47360.1 - 0.026 14.0 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4572 PF15139.6 CEG47361.1 - 0.058 13.3 0.3 0.67 9.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4572) ECH_1 PF00378.20 CEG47365.1 - 8e-37 126.9 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 CEG47365.1 - 1.4e-23 82.9 0.0 2.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein ECH_2 PF16113.5 CEG47365.1 - 4.8e-22 78.9 0.0 6.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3848 PF12959.7 CEG47365.1 - 0.13 12.3 0.4 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Ribosomal_L13e PF01294.18 CEG47367.1 - 0.097 12.5 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L13e LRR_8 PF13855.6 CEG47369.1 - 0.07 12.9 0.1 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat RXLR_WY PF18634.1 CEG47372.1 - 0.026 14.4 0.7 0.31 11.0 1.3 2.5 3 0 0 3 3 3 0 RXLR phytopathogen effector protein WY-domain DUF913 PF06025.12 CEG47374.1 - 5.1e-39 134.3 3.4 2.9e-35 121.9 0.1 4.0 4 1 1 5 5 5 3 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CEG47374.1 - 1.6e-27 96.9 0.0 1.3e-14 54.5 0.0 2.4 1 1 1 2 2 2 2 Domain of Unknown Function (DUF908) PALP PF00291.25 CEG47375.1 - 3.4e-62 210.5 3.3 4.3e-62 210.2 3.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CEG47375.1 - 1.7e-34 117.4 0.1 1.1e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF760 PF05542.11 CEG47376.1 - 0.15 12.4 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF760) DUF3175 PF11373.8 CEG47377.1 - 0.055 13.7 4.6 0.33 11.1 1.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3175) Methyltransf_16 PF10294.9 CEG47378.1 - 1.9e-12 47.3 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase DUF1087 PF06465.13 CEG47378.1 - 0.023 14.7 0.1 0.049 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Nucleos_tra2_N PF01773.20 CEG47379.1 - 0.035 14.7 0.6 0.048 14.3 0.6 1.3 1 1 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus US10 PF17617.2 CEG47379.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Viral unique short region 10 HD_4 PF13328.6 CEG47382.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 HD domain DnaJ PF00226.31 CEG47384.1 - 1.1e-24 86.3 0.3 1.7e-24 85.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 CEG47385.1 - 3.7e-31 108.3 0.0 7.9e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG47385.1 - 8.6e-07 29.5 0.3 2.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG47385.1 - 1.4e-06 28.7 0.7 1.5e-05 25.3 0.2 2.5 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CEG47385.1 - 9.9e-06 26.1 0.0 3.1e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CEG47385.1 - 6.8e-05 23.2 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CEG47385.1 - 7.1e-05 22.9 0.0 0.00052 20.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG47385.1 - 0.00016 21.9 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CEG47385.1 - 0.00024 21.3 0.0 0.00055 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CEG47385.1 - 0.00037 20.8 0.0 0.0008 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CEG47385.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CEG47385.1 - 0.0014 18.5 0.1 0.0022 17.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEG47385.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CEG47385.1 - 0.002 18.1 0.4 0.009 15.9 0.4 2.2 1 1 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 CEG47385.1 - 0.0028 17.4 0.1 0.0073 16.1 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase AAA_5 PF07728.14 CEG47385.1 - 0.0029 17.6 0.0 0.0072 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CEG47385.1 - 0.0031 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEG47385.1 - 0.0044 16.6 1.0 0.27 10.8 0.1 2.2 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEG47385.1 - 0.0044 16.8 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.15 CEG47385.1 - 0.0057 16.6 0.3 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 CEG47385.1 - 0.0061 16.5 0.1 3.8 7.4 0.0 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 CEG47385.1 - 0.0062 15.7 0.1 0.087 12.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CEG47385.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 CEG47385.1 - 0.012 16.0 0.3 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CEG47385.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 CEG47385.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEG47385.1 - 0.023 15.0 0.1 0.096 13.0 0.0 2.1 3 0 0 3 3 1 0 AAA domain ResIII PF04851.15 CEG47385.1 - 0.031 14.3 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CEG47385.1 - 0.034 14.6 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CEG47385.1 - 0.038 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEG47385.1 - 0.044 13.1 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 CEG47385.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEG47385.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CEG47385.1 - 0.089 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 CEG47385.1 - 0.094 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 CEG47385.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 CEG47385.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CEG47386.1 - 4.5e-42 143.8 4.2 3e-20 73.1 0.0 4.2 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 CEG47386.1 - 3.5e-16 59.9 16.1 0.00018 21.5 0.0 5.3 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG47386.1 - 3.8e-11 42.9 1.1 0.00055 19.4 0.0 4.1 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG47386.1 - 2e-07 30.7 0.2 0.014 15.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 CEG47386.1 - 4.8e-07 29.8 0.1 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 CEG47386.1 - 6e-07 30.2 11.6 0.0014 19.1 0.0 3.7 4 1 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CEG47386.1 - 1.7e-06 28.5 0.3 0.074 13.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CEG47386.1 - 2.1e-06 27.7 10.2 5.5e-05 23.0 0.0 3.9 5 0 0 5 5 4 2 AAA ATPase domain AAA PF00004.29 CEG47386.1 - 2e-05 25.0 0.2 0.48 10.8 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEG47386.1 - 2.1e-05 24.1 0.1 0.03 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 CEG47386.1 - 5.7e-05 23.4 0.0 0.67 10.4 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 CEG47386.1 - 9.2e-05 22.3 1.7 0.54 10.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CEG47386.1 - 0.0001 22.1 0.1 0.033 13.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CEG47386.1 - 0.00011 22.0 1.6 0.13 12.0 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 CEG47386.1 - 0.00011 22.4 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEG47386.1 - 0.00016 21.6 1.5 0.6 10.0 0.2 3.1 2 1 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 CEG47386.1 - 0.00018 21.5 3.5 0.00066 19.7 3.5 1.9 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.14 CEG47386.1 - 0.00027 20.9 2.3 0.13 12.2 0.0 3.1 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEG47386.1 - 0.00031 20.8 0.9 3.2 7.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CEG47386.1 - 0.00033 20.3 2.4 0.016 14.8 0.0 3.0 4 0 0 4 4 2 1 AAA domain AAA_22 PF13401.6 CEG47386.1 - 0.00068 19.9 5.1 0.16 12.2 0.1 3.7 3 2 0 3 3 2 2 AAA domain SRP54 PF00448.22 CEG47386.1 - 0.00086 19.0 0.4 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CEG47386.1 - 0.00087 19.4 0.4 2.2 8.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 CEG47386.1 - 0.001 19.2 0.1 0.4 10.9 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 CEG47386.1 - 0.0011 18.4 0.0 0.037 13.4 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CEG47386.1 - 0.0011 19.1 0.0 2.4 8.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG47386.1 - 0.0015 19.1 0.3 0.47 11.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CEG47386.1 - 0.002 18.1 0.3 0.56 10.1 0.1 2.9 2 0 0 2 2 2 1 NTPase KAP_NTPase PF07693.14 CEG47386.1 - 0.0036 16.6 5.7 0.73 9.0 4.2 3.1 2 1 0 2 2 2 1 KAP family P-loop domain TsaE PF02367.17 CEG47386.1 - 0.0094 15.9 0.1 0.47 10.5 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CEG47386.1 - 0.012 15.4 0.3 0.54 10.0 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.17 CEG47386.1 - 0.057 13.1 1.1 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase Ploopntkinase3 PF18751.1 CEG47386.1 - 0.058 13.3 1.6 9.4 6.1 0.0 3.3 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 CEG47386.1 - 0.067 13.1 0.2 0.29 11.0 0.0 2.2 2 0 0 2 2 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 CEG47386.1 - 0.07 12.3 4.8 1.1 8.4 0.0 3.0 3 1 0 3 3 2 0 NB-ARC domain ATP_bind_1 PF03029.17 CEG47386.1 - 0.092 12.5 0.6 8.6 6.1 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-RanBP PF00641.18 CEG47387.1 - 0.00091 18.5 8.6 0.0018 17.5 8.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CEG47387.1 - 0.2 11.0 6.4 1.8 8.0 6.9 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Dynein_light PF01221.18 CEG47388.1 - 4.2e-21 75.0 0.1 1.7e-11 44.2 0.1 2.4 2 0 0 2 2 2 2 Dynein light chain type 1 Doppel PF11466.8 CEG47388.1 - 1.6 8.5 5.1 8.9 6.1 0.1 2.5 2 0 0 2 2 2 0 Prion-like protein Doppel SIR2 PF02146.17 CEG47389.1 - 3e-54 183.6 0.0 2e-53 180.9 0.0 2.2 2 0 0 2 2 2 1 Sir2 family PHD PF00628.29 CEG47389.1 - 5.5e-06 26.2 5.7 5.5e-06 26.2 5.7 3.7 3 1 0 3 3 3 1 PHD-finger ZZ PF00569.17 CEG47389.1 - 0.00012 21.8 7.4 0.00012 21.8 7.4 4.3 5 0 0 5 5 5 1 Zinc finger, ZZ type TPP_enzyme_M PF00205.22 CEG47389.1 - 0.00048 19.9 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain C1_1 PF00130.22 CEG47389.1 - 0.0015 18.4 3.4 0.0015 18.4 3.4 3.8 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYND PF01753.18 CEG47392.1 - 7.9e-06 25.9 11.7 7.9e-06 25.9 11.7 2.7 2 0 0 2 2 2 1 MYND finger SET PF00856.28 CEG47392.1 - 0.00052 20.4 0.0 0.0011 19.3 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-Mss51 PF13824.6 CEG47392.1 - 0.43 10.7 9.0 0.45 10.6 4.1 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Pkinase_Tyr PF07714.17 CEG47394.1 - 4.5e-27 95.0 0.0 3e-26 92.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG47394.1 - 5.6e-24 84.9 0.0 8.9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Jacalin PF01419.17 CEG47396.1 - 6.2e-08 32.6 0.0 7.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Jacalin-like lectin domain TUDOR_5 PF18359.1 CEG47399.1 - 1.1e-11 44.3 0.4 3.5e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 CEG47399.1 - 0.13 12.8 0.1 11 6.6 0.0 3.3 2 0 0 2 2 2 0 Agenet domain MoaC PF01967.21 CEG47400.1 - 1.5e-20 73.7 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 MoaC family CTD_bind PF04818.13 CEG47401.1 - 2.5e-09 37.8 0.0 7.1e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 CEG47401.1 - 0.015 15.8 0.3 0.015 15.8 0.3 3.2 4 0 0 4 4 4 0 Subunit of cleavage factor IA Pcf11 zf-BED PF02892.15 CEG47401.1 - 0.083 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 BED zinc finger Jacalin PF01419.17 CEG47402.1 - 8.9e-06 25.7 0.1 0.00059 19.8 0.0 2.0 2 0 0 2 2 2 2 Jacalin-like lectin domain WW PF00397.26 CEG47405.1 - 4.8e-10 39.4 2.4 7.3e-10 38.8 2.4 1.3 1 0 0 1 1 1 1 WW domain DNA_pol_B_thumb PF14791.6 CEG47405.1 - 0.0047 17.0 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta thumb UBA2_C PF16195.5 CEG47406.1 - 0.12 13.1 0.1 0.15 12.7 0.1 1.2 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Carboxyl_trans PF01039.22 CEG47407.1 - 2.7e-08 32.9 0.0 2.9e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MPC PF03650.13 CEG47408.1 - 2.3e-38 130.7 0.3 2.5e-38 130.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Myb_DNA-binding PF00249.31 CEG47411.1 - 0.0032 17.6 0.1 0.0099 16.1 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Hamartin PF04388.12 CEG47416.1 - 0.012 14.3 0.7 0.013 14.2 0.7 1.0 1 0 0 1 1 1 0 Hamartin protein PreAtp-grasp PF18604.1 CEG47416.1 - 0.063 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain Chromo PF00385.24 CEG47418.1 - 9.8e-05 22.2 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 2OG-FeII_Oxy PF03171.20 CEG47419.1 - 2e-20 73.1 0.1 3.2e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CEG47419.1 - 9.8e-20 71.5 0.0 1.9e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Nsp1_C PF05064.13 CEG47420.1 - 3.2e-19 68.8 1.4 3.2e-19 68.8 1.4 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region TACC_C PF05010.14 CEG47420.1 - 0.0093 15.8 3.4 0.017 14.9 3.4 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Herpes_UL25 PF01499.16 CEG47420.1 - 0.1 11.1 2.0 0.16 10.5 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DASH_Dad2 PF08654.10 CEG47420.1 - 0.14 12.6 6.1 6.3 7.3 1.4 3.4 2 1 0 2 2 2 0 DASH complex subunit Dad2 Nucleoporin_FG2 PF15967.5 CEG47420.1 - 0.17 10.4 89.3 0.089 11.3 59.6 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeated region DUF1664 PF07889.12 CEG47420.1 - 0.18 11.9 11.0 0.6 10.2 2.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 CEG47420.1 - 0.22 12.0 11.6 0.29 11.6 4.7 2.9 1 1 2 3 3 3 0 Snapin/Pallidin LMBR1 PF04791.16 CEG47420.1 - 0.25 10.2 6.1 0.94 8.3 6.1 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4164 PF13747.6 CEG47420.1 - 0.34 11.2 5.8 0.72 10.2 1.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4200 PF13863.6 CEG47420.1 - 0.44 11.0 4.0 0.44 11.0 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 CEG47420.1 - 0.79 8.5 9.9 1.8 7.4 9.2 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CEG47420.1 - 1 9.4 13.4 0.82 9.7 6.8 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.16 CEG47420.1 - 1.4 9.1 5.5 0.79 10.0 0.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 CEG47420.1 - 1.7 9.2 8.8 2.3 8.8 6.8 2.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 CEG47420.1 - 1.8 9.0 7.4 2.7 8.4 0.2 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 CEG47420.1 - 2 8.7 6.2 31 4.9 0.0 3.0 1 1 1 3 3 3 0 Uncharacterized conserved protein CLZ PF16526.5 CEG47420.1 - 2.3 8.6 6.6 18 5.8 0.4 3.0 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 CEG47420.1 - 2.6 7.6 10.2 4.3 6.9 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 CEG47420.1 - 6.1 7.0 10.0 4.8 7.4 6.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CEG47420.1 - 7.7 6.5 9.4 1.9 8.5 3.0 2.4 1 1 0 2 2 2 0 Laminin Domain II Fzo_mitofusin PF04799.13 CEG47420.1 - 8.7 5.9 6.5 5.3 6.6 1.0 2.4 1 1 0 2 2 2 0 fzo-like conserved region SCP-1 PF05483.12 CEG47421.1 - 0.03 12.3 0.5 0.026 12.5 0.5 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Aminotran_1_2 PF00155.21 CEG47422.1 - 3.7e-39 134.9 0.0 4.6e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEG47422.1 - 1.8e-05 23.5 0.0 2.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme KCT2 PF17818.1 CEG47423.1 - 0.0049 17.0 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Keratinocyte-associated gene product DUF3382 PF11862.8 CEG47423.1 - 0.016 15.5 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DUF4713 PF15831.5 CEG47423.1 - 0.33 11.4 5.1 0.41 11.1 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Glyco_hydro_38N PF01074.22 CEG47425.1 - 2.6e-67 227.2 9.6 2.3e-63 214.2 2.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CEG47425.1 - 6.7e-32 111.3 0.1 1.3e-31 110.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CEG47425.1 - 4.5e-19 68.4 0.0 1.6e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CEG47425.1 - 0.00021 21.3 0.0 0.0007 19.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Sorb PF02208.16 CEG47425.1 - 0.15 11.9 0.2 0.36 10.7 0.2 1.6 1 0 0 1 1 1 0 Sorbin homologous domain AAA_18 PF13238.6 CEG47427.1 - 5.9e-08 33.3 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEG47427.1 - 3.7e-06 27.2 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG47427.1 - 0.017 14.4 0.0 0.051 12.8 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CEG47427.1 - 0.027 14.9 0.0 0.093 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CEG47427.1 - 0.028 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CEG47427.1 - 0.036 14.3 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Endonuclease_NS PF01223.23 CEG47428.1 - 1.4e-56 191.9 0.0 1.8e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease LRR_4 PF12799.7 CEG47430.1 - 4e-20 71.6 46.7 2e-06 28.1 0.9 5.2 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG47430.1 - 9.3e-16 57.8 17.6 5.9e-12 45.4 4.9 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CEG47430.1 - 1.6e-14 53.4 33.1 3.5e-06 26.7 5.7 5.3 4 2 3 7 7 7 5 Leucine rich repeat LRR_3 PF07725.12 CEG47430.1 - 0.48 10.4 2.8 4.3 7.3 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat RPN1_RPN2_N PF17781.1 CEG47431.1 - 1.9e-116 388.8 0.3 3.8e-116 387.8 0.3 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CEG47431.1 - 1.1e-31 108.7 0.1 2.6e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CEG47431.1 - 1.5e-26 91.5 22.2 6.3e-05 23.2 0.1 8.7 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CEG47431.1 - 2.5e-05 24.6 4.7 0.08 13.3 0.2 4.6 4 1 1 6 6 6 3 HEAT repeats HTH_38 PF13936.6 CEG47434.1 - 0.00041 20.0 0.0 0.00075 19.2 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 CEG47434.1 - 0.031 14.1 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain AAA_29 PF13555.6 CEG47435.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain fn3 PF00041.21 CEG47440.1 - 2.9e-34 117.2 5.4 0.00018 21.8 0.0 10.0 9 0 0 9 9 9 8 Fibronectin type III domain Aminotran_3 PF00202.21 CEG47441.1 - 4e-109 364.9 0.0 1.2e-108 363.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-III His_Phos_1 PF00300.22 CEG47441.1 - 9.2e-48 162.5 0.0 1.9e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Kinesin PF00225.23 CEG47441.1 - 7.2e-33 113.9 0.0 8e-29 100.6 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain C2 PF00168.30 CEG47441.1 - 8.6e-12 45.3 0.0 3.5e-08 33.7 0.0 2.9 2 0 0 2 2 2 2 C2 domain Exo_endo_phos PF03372.23 CEG47441.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Microtub_bd PF16796.5 CEG47441.1 - 0.0096 15.9 0.0 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Syntaxin-18_N PF10496.9 CEG47441.1 - 1.6 9.0 5.8 2.2 8.6 0.7 3.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus ANAPC4_WD40 PF12894.7 CEG47444.1 - 0.00047 20.4 0.5 9.8 6.6 0.0 4.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 CEG47444.1 - 0.042 13.6 0.4 6.2 6.5 0.0 3.4 2 1 1 3 3 3 0 TUP1-like enhancer of split PQQ PF01011.21 CEG47444.1 - 0.078 12.9 1.0 0.28 11.2 1.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat WD40 PF00400.32 CEG47444.1 - 0.61 11.1 5.9 7.4 7.6 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Spt5-NGN PF03439.13 CEG47445.1 - 8.6e-19 67.2 0.1 2.1e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 CEG47445.1 - 8.2e-12 46.0 18.1 8.2e-12 46.0 18.1 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 CEG47445.1 - 0.019 15.4 8.7 0.019 15.4 8.7 3.2 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 CEG47445.1 - 2.1 8.1 20.4 2.4 7.9 19.1 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Glyco_hydro_7 PF00840.20 CEG47451.1 - 1.7e-193 643.2 12.8 2e-193 643.0 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Albumin_I_a PF16720.5 CEG47452.1 - 4.4 7.3 14.1 4.4 7.3 0.6 3.9 2 1 2 4 4 4 0 Albumin I chain a RWP-RK PF02042.15 CEG47453.1 - 1.4e-09 37.8 0.1 6.7e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 RWP-RK domain DUF134 PF02001.16 CEG47453.1 - 0.17 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 RWP-RK PF02042.15 CEG47454.1 - 1.9e-11 43.7 0.0 1.7e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 RWP-RK domain Sigma70_r4_2 PF08281.12 CEG47454.1 - 0.0035 17.0 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MDM31_MDM32 PF08118.11 CEG47455.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Dimer_Tnp_hAT PF05699.14 CEG47456.1 - 9e-10 38.2 1.3 1.6e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CEG47456.1 - 4e-06 26.7 0.2 4e-06 26.7 0.2 2.1 2 0 0 2 2 2 1 BED zinc finger TetR_C_33 PF13305.6 CEG47456.1 - 0.11 13.2 0.0 2 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HSP70 PF00012.20 CEG47457.1 - 1.8e-210 700.2 2.5 2.4e-210 699.8 2.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG47457.1 - 3.9e-16 58.8 0.2 2.6e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEG47457.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CEG47457.1 - 0.023 13.7 0.2 0.13 11.2 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain ADP_PFK_GK PF04587.15 CEG47457.1 - 0.031 12.9 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Hydantoinase_A PF01968.18 CEG47457.1 - 0.06 12.6 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase RRM_5 PF13893.6 CEG47458.1 - 3.4e-43 146.2 0.0 1.4e-20 73.1 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CEG47458.1 - 8e-32 108.9 0.2 8.5e-09 35.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CEG47458.1 - 4.8e-15 55.5 0.2 1.9e-14 53.6 0.1 2.0 2 0 0 2 2 2 1 RRM-like domain Limkain-b1 PF11608.8 CEG47458.1 - 0.00072 19.6 0.0 0.68 10.0 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 RL PF17797.1 CEG47458.1 - 0.0026 17.7 0.5 0.059 13.3 0.0 3.2 4 0 0 4 4 4 1 RL domain NKWYS PF10364.9 CEG47458.1 - 0.065 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein RRM_7 PF16367.5 CEG47458.1 - 0.066 13.3 0.0 12 6.1 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif BRAP2 PF07576.12 CEG47458.1 - 3.8 7.8 5.1 15 5.9 0.1 3.5 4 1 1 5 5 5 0 BRCA1-associated protein 2 Arf PF00025.21 CEG47459.1 - 3.1e-79 264.5 0.0 3.5e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG47459.1 - 1.1e-14 54.7 0.0 1.5e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG47459.1 - 6.3e-13 48.6 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEG47459.1 - 9.6e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEG47459.1 - 4.3e-12 45.9 0.7 4.9e-08 32.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEG47459.1 - 5.2e-09 35.8 0.0 6.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG47459.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEG47459.1 - 0.0097 15.2 0.1 0.012 14.9 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase PAP_central PF04928.17 CEG47462.1 - 2.1e-40 138.3 0.9 5e-40 137.0 0.1 1.9 3 0 0 3 3 3 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEG47462.1 - 3.2e-23 82.2 0.1 7.5e-23 81.0 0.1 1.6 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain ANAPC1 PF12859.7 CEG47463.1 - 5.9e-18 65.7 0.0 1.2e-15 58.2 0.0 3.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CEG47463.1 - 4.9e-08 33.0 5.2 0.00066 20.0 0.0 5.0 4 0 0 4 4 4 2 Proteasome/cyclosome repeat AAA PF00004.29 CEG47464.1 - 9.6e-58 194.3 0.0 9.7e-43 145.8 0.0 3.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CEG47464.1 - 6.3e-23 81.0 1.7 2e-22 79.4 1.7 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CEG47464.1 - 1.3e-12 48.5 2.2 0.00069 20.0 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 CEG47464.1 - 5.6e-10 39.6 1.9 0.017 15.4 0.5 4.6 2 2 1 3 3 3 2 AAA domain NACHT PF05729.12 CEG47464.1 - 6.5e-08 32.7 0.1 0.00026 20.9 0.0 2.9 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.27 CEG47464.1 - 9.5e-08 32.7 0.1 7.5e-05 23.3 0.0 3.1 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 CEG47464.1 - 2.7e-07 30.4 1.2 0.2 11.2 0.1 4.4 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.6 CEG47464.1 - 4.9e-07 29.9 0.0 0.007 16.4 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_5 PF07728.14 CEG47464.1 - 6.5e-07 29.4 0.0 0.022 14.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEG47464.1 - 5.3e-06 26.6 0.0 0.02 15.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEG47464.1 - 6.9e-06 26.4 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 CEG47464.1 - 8.1e-06 25.7 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CEG47464.1 - 1e-05 25.3 0.0 0.0003 20.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CEG47464.1 - 1.3e-05 24.9 0.0 0.0097 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain Zeta_toxin PF06414.12 CEG47464.1 - 2.1e-05 23.9 0.0 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ATPase_2 PF01637.18 CEG47464.1 - 2.1e-05 24.6 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CEG47464.1 - 3.7e-05 23.5 0.1 0.049 13.4 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 CEG47464.1 - 0.00017 20.8 0.0 0.46 9.6 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain AAA_17 PF13207.6 CEG47464.1 - 0.00033 21.1 0.7 0.41 11.1 0.1 3.1 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 CEG47464.1 - 0.00048 20.1 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CEG47464.1 - 0.00051 19.3 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEG47464.1 - 0.00073 20.1 0.0 0.48 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEG47464.1 - 0.0012 18.5 0.3 6.1 6.5 0.0 3.8 3 1 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CEG47464.1 - 0.0014 18.1 0.1 0.075 12.4 0.1 2.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CEG47464.1 - 0.0017 18.0 0.0 0.17 11.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TIP49 PF06068.13 CEG47464.1 - 0.0024 17.1 0.0 0.041 13.1 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 CEG47464.1 - 0.0041 16.6 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 CEG47464.1 - 0.0045 17.5 0.4 0.31 11.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.15 CEG47464.1 - 0.008 15.0 0.3 0.029 13.2 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_2 PF07724.14 CEG47464.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DAP3 PF10236.9 CEG47464.1 - 0.016 14.4 0.1 11 5.1 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 CEG47464.1 - 0.018 14.3 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CEG47464.1 - 0.025 14.3 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CEG47464.1 - 0.026 14.5 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_3 PF07726.11 CEG47464.1 - 0.027 14.3 0.0 0.75 9.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEG47464.1 - 0.046 14.0 0.0 0.64 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEG47464.1 - 0.05 12.7 0.0 0.79 8.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.18 CEG47464.1 - 0.1 11.8 0.1 3 7.1 0.0 2.9 3 0 0 3 3 3 0 Septin AAA_30 PF13604.6 CEG47464.1 - 0.11 12.2 0.1 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEG47464.1 - 0.19 11.7 0.0 28 4.6 0.0 2.9 3 0 0 3 3 3 0 NTPase Nop52 PF05997.12 CEG47466.1 - 1.3e-29 103.6 2.5 2e-29 102.9 2.5 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 POTRA_1 PF08478.10 CEG47466.1 - 0.053 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 POTRA domain, FtsQ-type CNDH2_C PF16858.5 CEG47466.1 - 0.057 13.3 0.5 0.098 12.5 0.0 1.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Glyco_hydro_32N PF00251.20 CEG47466.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DPBB_1 PF03330.18 CEG47468.1 - 2e-07 31.2 0.0 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEG47468.1 - 5.5e-05 23.0 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 Barwin family MCM PF00493.23 CEG47470.1 - 8.3e-102 339.0 0.2 1.4e-101 338.3 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEG47470.1 - 2.8e-38 130.6 0.0 5.9e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEG47470.1 - 7e-24 84.1 2.7 1.5e-23 83.0 2.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEG47470.1 - 3e-17 63.1 2.4 9.3e-17 61.5 2.4 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM6_C PF18263.1 CEG47470.1 - 2.5e-15 56.6 2.7 2.9e-14 53.2 2.7 2.5 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CEG47470.1 - 1.2e-09 37.8 0.0 2.3e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEG47470.1 - 0.0014 18.6 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEG47470.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 CEG47470.1 - 0.0064 17.1 3.3 0.77 10.4 0.1 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 CEG47470.1 - 0.0074 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Filament_head PF04732.14 CEG47471.1 - 1.9 9.4 16.4 1.7 9.6 14.8 1.8 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region Aminotran_5 PF00266.19 CEG47472.1 - 1.6e-88 297.1 0.0 2.1e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEG47472.1 - 1.1e-07 31.5 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEG47472.1 - 0.0045 16.3 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CEG47472.1 - 0.017 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AAA_35 PF14516.6 CEG47474.1 - 1.2e-08 34.2 0.0 7.4e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.6 CEG47474.1 - 0.00018 21.5 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEG47474.1 - 0.00052 20.4 0.0 0.00089 19.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG47474.1 - 0.0023 18.3 0.1 2.5 8.5 0.2 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CEG47474.1 - 0.004 17.4 0.1 0.11 12.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain TruB-C_2 PF09157.11 CEG47474.1 - 0.014 15.4 0.2 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal DUF190 PF02641.15 CEG47474.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 Trypsin_2 PF13365.6 CEG47476.1 - 1.6e-32 113.5 0.0 3e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG47476.1 - 7.3e-16 58.7 0.1 1.3e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 CEG47476.1 - 7.1e-13 48.7 0.5 1.4e-12 47.8 0.5 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG47476.1 - 2.5e-10 40.0 0.0 6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG47476.1 - 1.2e-07 32.0 0.2 2.9e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 CEG47476.1 - 1.1e-05 24.4 0.8 0.036 12.7 0.3 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S7 PF00949.21 CEG47476.1 - 0.0014 18.4 0.8 0.0049 16.7 0.2 2.1 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 CEG47476.1 - 0.015 14.8 0.4 0.12 11.9 0.4 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S32 PF05579.13 CEG47476.1 - 0.049 12.8 0.9 1.2 8.2 0.2 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_C4 PF00863.19 CEG47476.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C4 Pkinase_Tyr PF07714.17 CEG47477.1 - 1.4e-47 162.2 0.0 1.8e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG47477.1 - 8.3e-43 146.7 0.0 1.3e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEG47477.1 - 2.2e-05 23.9 0.0 0.0001 21.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEG47477.1 - 0.0062 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEG47477.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2202 PF09968.9 CEG47477.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) RXLR PF16810.5 CEG47479.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity RNase_Zc3h12a PF11977.8 CEG47481.1 - 5.8e-18 65.2 1.3 2.2e-17 63.3 0.1 2.1 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 CEG47481.1 - 4e-06 26.5 1.7 6.6e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Protein-only RNase P KH_1 PF00013.29 CEG47481.1 - 0.00095 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF5615 PF18480.1 CEG47481.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Takusan PF04822.13 CEG47483.1 - 0.0059 16.5 0.1 0.0078 16.1 0.1 1.3 1 1 0 1 1 1 1 Takusan tRNA-synt_His PF13393.6 CEG47486.1 - 9.8e-32 110.4 0.4 1.5e-18 67.1 0.2 2.4 2 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CEG47486.1 - 1.8e-13 50.4 0.1 3.6e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CEG47486.1 - 3.8e-12 46.5 0.0 4.7e-10 39.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CEG47486.1 - 0.053 13.0 0.1 0.11 11.9 0.1 1.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 CEG47487.1 - 1.7e-07 31.7 0.2 4.7e-05 23.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47487.1 - 2.2e-05 24.9 0.1 0.0022 18.5 0.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47487.1 - 5.7e-05 23.2 0.1 0.0065 16.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CEG47487.1 - 0.00042 20.5 0.2 0.015 15.6 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG47487.1 - 0.0036 17.7 0.3 0.28 11.7 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeat PDZ_6 PF17820.1 CEG47487.1 - 0.03 14.2 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 PDZ domain CCSAP PF15748.5 CEG47487.1 - 9.8 6.3 13.4 1.2 9.3 7.2 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated TMEM135_C_rich PF15982.5 CEG47489.1 - 1.8e-05 25.4 4.0 7.2e-05 23.4 0.8 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 CEG47489.1 - 4.7e-05 23.7 2.0 0.0088 16.4 0.3 2.4 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family LptF_LptG PF03739.14 CEG47490.1 - 0.02 13.8 0.3 0.035 12.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF4149 PF13664.6 CEG47490.1 - 0.1 13.0 0.6 0.18 12.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) GATase_7 PF13537.6 CEG47494.1 - 1.8e-06 27.9 0.0 0.29 11.0 0.0 3.7 3 0 0 3 3 3 3 Glutamine amidotransferase domain LicD PF04991.13 CEG47494.1 - 0.0058 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 LicD family PX PF00787.24 CEG47496.1 - 0.031 14.3 0.1 0.13 12.2 0.1 2.1 1 0 0 1 1 1 0 PX domain RNase_3_N PF18497.1 CEG47497.1 - 0.088 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain PX PF00787.24 CEG47500.1 - 2.2e-05 24.4 0.2 4.5e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 PX domain Lact-deh-memb PF09330.11 CEG47503.1 - 0.005 16.2 0.1 0.016 14.6 0.0 1.5 1 1 0 1 1 1 1 D-lactate dehydrogenase, membrane binding DUF3379 PF11859.8 CEG47503.1 - 0.029 13.7 0.2 0.036 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) rve PF00665.26 CEG47504.1 - 8.7e-21 74.3 0.1 1.8e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CEG47504.1 - 1.2e-09 37.9 0.0 2.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CEG47504.1 - 0.00021 21.0 0.0 0.00054 19.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEG47504.1 - 0.011 15.4 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 DDE superfamily endonuclease TSP_1 PF00090.19 CEG47504.1 - 0.098 12.9 1.5 0.3 11.3 1.5 1.8 1 0 0 1 1 1 0 Thrombospondin type 1 domain CK2S PF15011.6 CEG47505.1 - 0.052 13.4 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate zf-C3HC4_3 PF13920.6 CEG47506.1 - 3.9e-10 39.4 12.5 8.8e-10 38.3 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG47506.1 - 3.1e-09 37.0 12.8 7.4e-09 35.8 12.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG47506.1 - 2.2e-08 33.8 13.5 4.4e-08 32.8 13.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG47506.1 - 1e-07 31.6 12.7 2.3e-07 30.6 12.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG47506.1 - 1.8e-06 27.7 13.4 5.1e-06 26.3 13.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG47506.1 - 1.7e-05 24.7 13.2 3.9e-05 23.5 13.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG47506.1 - 2.6e-05 24.2 4.8 2.6e-05 24.2 4.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CEG47506.1 - 2.9e-05 24.3 13.0 5.5e-05 23.4 13.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 CEG47506.1 - 0.00078 19.0 7.6 0.0021 17.7 7.6 1.6 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4_4 PF15227.6 CEG47506.1 - 0.0012 19.0 8.6 0.0036 17.4 8.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CEG47506.1 - 0.0034 17.1 9.9 0.0082 15.9 9.5 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CEG47506.1 - 0.0073 16.3 8.6 0.014 15.4 8.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 CEG47506.1 - 1.4 8.5 11.9 1.9 8.1 2.5 2.8 3 0 0 3 3 3 0 RecR protein zf-RING_11 PF17123.5 CEG47506.1 - 2.6 7.9 11.5 0.57 10.0 6.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger Esterase PF00756.20 CEG47508.1 - 0.059 13.0 0.1 0.079 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative esterase PWWP PF00855.17 CEG47508.1 - 0.2 12.1 1.5 0.32 11.4 0.5 1.8 2 0 0 2 2 2 0 PWWP domain Pkinase PF00069.25 CEG47509.1 - 2e-67 227.4 0.0 3e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47509.1 - 9e-42 143.1 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATG11 PF10377.9 CEG47509.1 - 3.3e-33 114.5 0.0 1.7e-15 57.2 0.0 2.9 3 0 0 3 3 3 2 Autophagy-related protein 11 Kdo PF06293.14 CEG47509.1 - 0.0013 18.1 0.2 0.0022 17.4 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 CEG47509.1 - 0.0028 17.8 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kinase-like PF14531.6 CEG47509.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CEG47509.1 - 0.18 11.7 0.0 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRTM1 PF15872.5 CEG47513.1 - 0.022 14.9 0.8 0.025 14.7 0.8 1.1 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Ribosomal_L37e PF01907.19 CEG47516.1 - 1.2e-27 95.8 10.2 2.8e-27 94.6 10.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CEG47516.1 - 0.032 14.3 1.2 0.052 13.6 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 CEG47516.1 - 0.11 12.6 1.7 0.19 11.9 1.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 HypA PF01155.19 CEG47516.1 - 0.16 12.0 0.7 0.25 11.4 0.7 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S14 PF00253.21 CEG47516.1 - 0.29 10.9 0.2 0.29 10.9 0.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF2688 PF10892.8 CEG47516.1 - 1.4 8.5 5.1 4.1 6.9 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) WD40 PF00400.32 CEG47519.1 - 7.5e-12 45.6 6.6 0.18 12.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat PknG_rubred PF16919.5 CEG47519.1 - 5.6 7.1 6.9 1 9.5 2.3 2.1 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Vac14_Fig4_bd PF11916.8 CEG47520.1 - 2.1e-69 232.7 8.4 5.4e-69 231.4 6.9 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CEG47520.1 - 8.5e-50 167.3 0.5 2.8e-42 143.2 0.0 4.6 2 1 3 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CEG47520.1 - 5.5e-15 54.2 3.5 8.3e-05 22.5 0.0 7.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 CEG47520.1 - 3.5e-10 40.2 0.8 0.02 15.4 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 CEG47520.1 - 8.9e-09 35.6 7.2 0.0017 18.4 0.0 5.6 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEG47520.1 - 7e-08 32.3 0.5 0.00027 20.6 0.0 4.0 3 2 2 5 5 5 2 CLASP N terminal HEAT_2 PF13646.6 CEG47520.1 - 1.1e-07 32.1 1.2 1.1 9.7 0.0 5.4 5 1 0 5 5 5 3 HEAT repeats Tti2 PF10521.9 CEG47520.1 - 5e-05 23.0 0.3 0.039 13.5 0.0 3.2 3 0 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 CEG47520.1 - 0.00019 21.6 3.0 0.017 15.3 0.3 4.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 CEG47520.1 - 0.00098 18.9 0.3 0.13 12.0 0.2 2.6 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis ParcG PF10274.9 CEG47520.1 - 0.0035 17.5 0.7 0.04 14.0 0.3 2.7 1 1 1 2 2 2 1 Parkin co-regulated protein RasGEF_N_2 PF14663.6 CEG47520.1 - 0.0081 16.5 3.9 4.8 7.6 0.0 4.7 3 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 CEG47520.1 - 0.019 15.0 0.4 17 5.6 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat E1-E2_ATPase PF00122.20 CEG47521.1 - 2e-32 112.2 2.5 7.4e-22 77.7 1.2 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEG47521.1 - 2e-30 105.9 2.7 6.8e-30 104.1 0.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEG47521.1 - 2.1e-18 66.2 0.1 4.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG47521.1 - 2e-14 54.4 0.3 3.9e-13 50.2 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG47521.1 - 2.3e-11 43.2 0.0 6.7e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG47521.1 - 7.2e-05 22.6 0.2 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 CEG47521.1 - 5.4 7.4 13.1 0.47 10.7 0.1 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) ANAPC4_WD40 PF12894.7 CEG47522.1 - 1.3e-21 76.7 2.5 0.0061 16.8 0.2 8.6 4 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG47522.1 - 3.3e-13 49.9 30.1 0.005 17.7 0.1 9.9 10 0 0 10 10 10 4 WD domain, G-beta repeat HPS3_N PF14761.6 CEG47522.1 - 1.5e-05 24.7 0.5 0.0081 15.7 0.1 4.2 5 0 0 5 5 5 1 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 CEG47522.1 - 6.4e-05 21.5 0.1 0.18 10.1 0.0 3.7 3 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 CEG47522.1 - 7.9e-05 21.6 1.6 0.94 8.1 0.0 5.1 3 2 2 5 5 5 2 Nup133 N terminal like PQQ_2 PF13360.6 CEG47522.1 - 0.00015 21.4 0.2 0.051 13.2 0.4 4.1 2 2 0 2 2 2 1 PQQ-like domain MRJP PF03022.16 CEG47522.1 - 0.083 12.2 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 Major royal jelly protein PD40 PF07676.12 CEG47522.1 - 0.18 11.8 0.5 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CK_II_beta PF01214.18 CEG47523.1 - 5.7e-76 254.4 0.0 8e-76 253.9 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF5521 PF17659.1 CEG47524.1 - 2.7e-21 75.2 1.6 8.5e-09 33.8 0.0 3.1 3 0 0 3 3 3 3 Family of unknown function (DUF5521) Rep-A_N PF04057.12 CEG47524.1 - 0.00037 20.5 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain DUF5088 PF17008.5 CEG47524.1 - 0.011 15.5 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 CEG47524.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PH PF00169.29 CEG47526.1 - 4e-08 33.7 0.0 1.2e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG47526.1 - 0.00071 19.8 0.0 0.0024 18.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RVT_1 PF00078.27 CEG47527.1 - 0.00026 20.6 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FYVE PF01363.21 CEG47529.1 - 2.1e-19 69.4 9.8 5.1e-19 68.2 9.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 CEG47529.1 - 1e-18 67.5 0.2 2.2e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 C2 domain Pex24p PF06398.11 CEG47529.1 - 0.0032 16.5 10.8 0.0032 16.5 10.8 1.7 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin FYVE_2 PF02318.16 CEG47529.1 - 0.021 15.1 7.5 0.055 13.7 7.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger PhoR PF11808.8 CEG47529.1 - 3.5 8.1 8.2 2.5 8.6 0.4 2.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Acatn PF13000.7 CEG47530.1 - 8e-125 417.4 15.2 1.2e-74 251.8 4.4 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 BT1 PF03092.16 CEG47530.1 - 0.0056 15.0 3.1 0.56 8.4 0.4 2.3 2 0 0 2 2 2 2 BT1 family Skp1 PF01466.19 CEG47531.1 - 0.00078 19.5 0.1 0.0041 17.2 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CEG47531.1 - 0.019 15.1 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Ferlin_C PF16165.5 CEG47531.1 - 3.6 7.5 5.1 6.8 6.6 5.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Sec62 PF03839.16 CEG47531.1 - 6.2 6.3 7.0 12 5.3 7.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Mannosyl_trans3 PF11051.8 CEG47532.1 - 1.3e-31 110.0 0.0 2.1e-30 106.0 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative PP2C PF00481.21 CEG47533.1 - 5.5e-50 170.4 0.1 3.5e-49 167.8 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG47533.1 - 0.0019 17.9 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C ATP-synt_I PF03899.15 CEG47533.1 - 0.02 15.2 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 ATP synthase I chain CAP PF00188.26 CEG47534.1 - 1.8e-21 77.3 4.7 1.8e-21 77.3 4.7 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family EVI2A PF05399.11 CEG47534.1 - 0.038 13.6 6.7 0.08 12.5 6.7 1.6 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Pkinase_Tyr PF07714.17 CEG47536.1 - 3.4e-44 151.1 0.0 1.5e-43 149.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG47536.1 - 7.5e-41 140.2 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 CEG47537.1 - 8e-11 41.1 15.5 0.6 10.3 0.5 7.3 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 CEG47537.1 - 0.0048 17.3 6.0 0.63 10.5 0.0 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) Glyco_transf_20 PF00982.21 CEG47538.1 - 8.1e-72 242.4 0.0 1.1e-71 241.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEG47538.1 - 1.5e-50 171.5 0.0 2.4e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEG47538.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 CEG47539.1 - 1.9e-09 37.9 14.7 0.00076 19.9 0.1 6.4 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG47539.1 - 3.9e-09 35.9 22.9 0.046 13.8 0.5 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG47539.1 - 1.2e-08 35.1 27.6 0.00071 19.7 1.8 5.6 3 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEG47539.1 - 7.6e-07 29.2 1.8 0.00085 19.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG47539.1 - 7.6e-05 23.3 5.7 0.31 11.7 1.4 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG47539.1 - 0.0074 16.3 4.1 5.4 7.2 0.2 3.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CEG47539.1 - 0.024 15.4 9.1 19 6.4 0.4 6.3 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG47539.1 - 0.028 14.3 6.8 8.7 6.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1447 PF07288.11 CEG47539.1 - 0.15 12.2 0.6 4.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) TPR_6 PF13174.6 CEG47539.1 - 0.15 12.7 20.8 0.72 10.6 0.4 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEG47539.1 - 0.59 10.2 15.9 0.19 11.8 3.7 4.5 2 2 2 4 4 4 0 Putative TPR-like repeat TPR_12 PF13424.6 CEG47539.1 - 1.2 9.4 16.2 24 5.3 1.4 6.1 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG47539.1 - 1.3 9.2 11.2 7.2 6.9 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG47539.1 - 1.9 8.4 22.2 0.62 10.0 0.6 6.5 9 0 0 9 9 9 0 Tetratricopeptide repeat RRM_1 PF00076.22 CEG47540.1 - 2.8e-24 84.7 0.0 1.6e-10 40.6 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG47540.1 - 0.0015 18.3 0.0 0.26 11.2 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif PGI PF00342.19 CEG47541.1 - 2.3e-190 633.4 0.0 3.3e-190 632.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase LRR_4 PF12799.7 CEG47541.1 - 1.2e-11 44.7 4.9 0.11 13.0 0.0 7.8 8 0 0 8 8 8 2 Leucine Rich repeats (2 copies) Methyltransf_31 PF13847.6 CEG47541.1 - 3.7e-10 39.8 0.1 1.3e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain LRR_6 PF13516.6 CEG47541.1 - 2.4e-08 33.3 21.0 0.14 12.3 0.0 11.0 12 0 0 12 12 11 3 Leucine Rich repeat Methyltransf_25 PF13649.6 CEG47541.1 - 2.5e-08 34.5 2.1 5.5e-08 33.4 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG47541.1 - 5.5e-08 33.5 0.1 7.1e-07 29.9 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain IQ PF00612.27 CEG47541.1 - 3.9e-06 26.2 79.5 0.022 14.5 1.0 11.5 11 0 0 11 11 11 7 IQ calmodulin-binding motif Methyltr_RsmB-F PF01189.17 CEG47541.1 - 4.6e-06 26.4 0.1 1.2e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 CEG47541.1 - 2.9e-05 23.7 0.0 8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CEG47541.1 - 9.3e-05 23.0 0.1 0.00038 21.0 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 CEG47541.1 - 0.00011 21.8 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 MraW methylase family Ubie_methyltran PF01209.18 CEG47541.1 - 0.0043 16.4 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-B_box PF00643.24 CEG47541.1 - 0.0059 16.7 6.5 0.012 15.8 6.5 1.5 1 0 0 1 1 1 1 B-box zinc finger Methyltransf_2 PF00891.18 CEG47541.1 - 0.017 14.5 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain C1_4 PF07975.12 CEG47541.1 - 0.19 12.0 4.1 0.74 10.1 4.1 2.0 1 0 0 1 1 1 0 TFIIH C1-like domain LRR_1 PF00560.33 CEG47541.1 - 0.27 11.9 15.3 47 5.1 0.1 7.7 8 1 0 8 8 5 0 Leucine Rich Repeat CEBP_ZZ PF16366.5 CEG47541.1 - 0.31 11.3 4.8 0.96 9.7 4.8 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 CEG47541.1 - 0.39 11.0 3.4 1.1 9.5 3.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PA14 PF07691.12 CEG47543.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 PA14 domain RRM_1 PF00076.22 CEG47546.1 - 1.9e-28 98.1 0.1 4.4e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG47546.1 - 0.00021 20.9 0.0 0.44 10.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG47546.1 - 0.00089 19.3 0.1 2.5 8.3 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif ARL2_Bind_BART PF11527.8 CEG47547.1 - 3.9e-28 97.9 2.8 3.9e-28 97.9 0.5 2.3 2 1 0 2 2 2 1 The ARF-like 2 binding protein BART DUF4758 PF15950.5 CEG47547.1 - 1.1 9.6 3.2 49 4.2 3.2 2.3 1 1 0 1 1 1 0 Putative sperm flagellar membrane protein PKD_channel PF08016.12 CEG47548.1 - 3.2e-10 39.3 9.7 6.9e-10 38.2 9.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CEG47548.1 - 1.2e-05 24.7 19.7 3.3e-05 23.2 16.3 2.3 1 1 1 2 2 2 1 Ion transport protein DUF3328 PF11807.8 CEG47548.1 - 0.41 10.4 0.1 0.41 10.4 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) TIL PF01826.17 CEG47551.1 - 1.4 9.2 6.5 0.28 11.5 1.3 2.2 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain NOG1_N PF17835.1 CEG47552.1 - 3.1e-18 66.3 0.0 4.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 CEG47552.1 - 8.5e-18 64.5 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 CEG47552.1 - 1.8e-16 59.6 0.0 3.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 CEG47552.1 - 8.1e-10 38.4 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.6 CEG47552.1 - 0.061 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CEG47552.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CEG47552.1 - 0.076 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CEG47552.1 - 0.11 12.5 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 CEG47552.1 - 0.14 12.6 0.0 0.32 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DS PF01916.17 CEG47554.1 - 2.5e-127 424.1 0.0 2.9e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase ASH PF15780.5 CEG47555.1 - 8e-31 106.1 16.8 0.00059 20.0 0.4 12.7 11 1 1 12 12 12 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CEG47555.1 - 1.7e-15 56.8 4.5 0.017 15.0 0.0 8.4 9 0 0 9 9 9 5 MSP (Major sperm protein) domain PapD-like PF14874.6 CEG47555.1 - 0.0021 18.2 1.8 3.5 7.8 0.1 5.3 7 0 0 7 7 7 1 Flagellar-associated PapD-like Clathrin PF00637.20 CEG47556.1 - 0.0014 18.5 0.9 0.13 12.1 0.2 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS GntR PF00392.21 CEG47556.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family zf-Di19 PF05605.12 CEG47556.1 - 0.094 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FtsJ PF01728.19 CEG47557.1 - 2.7e-56 190.5 0.1 5.1e-56 189.6 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CEG47557.1 - 3.9e-56 190.0 20.1 3.9e-56 190.0 20.1 3.0 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 CEG47557.1 - 3.4e-37 127.8 12.8 3.4e-37 127.8 12.8 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Metallophos PF00149.28 CEG47557.1 - 4e-08 34.0 0.1 9.2e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CoA_binding_3 PF13727.6 CEG47557.1 - 0.33 10.9 1.7 0.45 10.5 0.4 2.0 1 1 0 1 1 1 0 CoA-binding domain DUF4089 PF13318.6 CEG47560.1 - 0.11 13.0 0.2 0.15 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) ADH_N PF08240.12 CEG47561.1 - 1.6e-08 34.4 0.0 2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arm PF00514.23 CEG47562.1 - 0.068 13.2 1.0 11 6.3 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DNA_repr_REX1B PF14966.6 CEG47563.1 - 1.4e-23 83.4 3.9 2.9e-23 82.3 3.9 1.6 1 0 0 1 1 1 1 DNA repair REX1-B Acetyltransf_5 PF13444.6 CEG47563.1 - 0.015 16.0 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ENTH PF01417.20 CEG47563.1 - 0.015 15.4 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 ENTH domain DUF262 PF03235.14 CEG47563.1 - 0.026 14.7 2.7 0.031 14.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cyclin_N PF00134.23 CEG47564.1 - 2.4e-16 59.6 0.5 2.1e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 CEG47564.1 - 0.0088 16.1 0.6 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 CEG47564.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain Abhydrolase_1 PF00561.20 CEG47566.1 - 2.9e-16 59.9 0.0 2e-08 34.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG47566.1 - 9.8e-09 34.8 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG47566.1 - 2.1e-07 31.8 0.0 2.5e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 CEG47566.1 - 8.1e-05 21.5 0.2 0.00017 20.4 0.2 1.4 1 1 0 1 1 1 1 Ndr family Lipase PF00151.19 CEG47566.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipase DLH PF01738.18 CEG47566.1 - 0.021 14.4 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 CEG47566.1 - 0.023 14.5 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sugar-bind PF04198.13 CEG47566.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain VPS13_mid_rpt PF16910.5 CEG47567.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Repeating coiled region of VPS13 Ribosomal_60s PF00428.19 CEG47568.1 - 1.7e-12 47.8 4.1 2.1e-12 47.5 4.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein KfrA_N PF11740.8 CEG47568.1 - 0.063 14.0 0.1 0.081 13.6 0.1 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term AAA_6 PF12774.7 CEG47570.1 - 1.4e-156 520.5 0.0 4.7e-156 518.8 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG47570.1 - 9.5e-123 410.2 10.4 9.5e-123 410.2 10.4 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CEG47570.1 - 1.4e-109 366.1 3.0 1.3e-107 359.6 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CEG47570.1 - 5.2e-101 337.4 5.6 4.9e-100 334.1 0.0 4.3 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CEG47570.1 - 9.1e-92 306.1 0.2 9.1e-92 306.1 0.2 3.2 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CEG47570.1 - 2.2e-76 255.4 0.0 7.1e-75 250.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEG47570.1 - 6.6e-58 195.1 0.0 4.7e-57 192.4 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEG47570.1 - 5.3e-45 152.4 0.0 3e-42 143.5 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CEG47570.1 - 1.5e-42 145.9 3.5 1.5e-42 145.9 3.5 2.8 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CEG47570.1 - 3.4e-28 98.3 1.4 1.7e-27 96.1 0.4 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CEG47570.1 - 1.4e-18 66.9 0.1 6.8e-18 64.7 0.2 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CEG47570.1 - 7.1e-13 48.7 0.0 9.6e-05 22.4 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CEG47570.1 - 3.4e-07 30.2 0.0 0.00044 20.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CEG47570.1 - 1e-06 29.2 0.8 0.11 12.9 0.0 4.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEG47570.1 - 8.3e-06 25.1 0.0 3.6e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 CEG47570.1 - 0.00045 20.6 0.0 0.63 10.5 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CEG47570.1 - 0.0012 19.4 2.3 3.8 8.1 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.6 CEG47570.1 - 0.0038 17.6 0.4 0.23 11.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 CEG47570.1 - 0.017 15.4 0.0 0.11 12.7 0.0 2.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 CEG47570.1 - 0.022 14.1 0.0 4.7 6.5 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CEG47570.1 - 0.022 15.0 0.8 1.4 9.2 0.0 3.5 3 0 0 3 3 2 0 AAA domain DUF5341 PF17276.2 CEG47570.1 - 0.046 13.9 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5341) YjcZ PF13990.6 CEG47570.1 - 0.059 12.7 1.0 0.19 11.1 1.0 1.8 1 0 0 1 1 1 0 YjcZ-like protein IstB_IS21 PF01695.17 CEG47570.1 - 0.061 13.1 0.3 1.2 8.8 0.0 2.9 2 1 1 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 CEG47570.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Spectrin PF00435.21 CEG47570.1 - 3.6 8.1 12.5 0.43 11.1 2.0 3.5 2 0 0 2 2 2 0 Spectrin repeat Cyclin_C PF02984.19 CEG47571.1 - 4.4e-16 59.1 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CEG47571.1 - 4e-14 52.5 0.0 1.1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ank_2 PF12796.7 CEG47572.1 - 6.9e-41 138.7 9.9 3.6e-13 49.9 0.3 5.5 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG47572.1 - 1.2e-34 118.2 6.9 5.3e-07 30.1 0.0 7.3 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47572.1 - 2.4e-34 113.5 7.8 8.7e-05 22.6 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 CEG47572.1 - 3e-34 116.6 15.6 2.7e-08 33.9 0.0 8.2 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CEG47572.1 - 8.6e-30 101.9 18.0 9.6e-05 22.7 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat BTB PF00651.31 CEG47572.1 - 4.8e-12 46.1 0.1 1.4e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Cnd1_N PF12922.7 CEG47572.1 - 0.19 11.6 3.6 0.49 10.2 1.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term ARPC4 PF05856.12 CEG47573.1 - 1.8e-57 193.6 7.1 1.1e-29 103.3 2.4 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) Cyt-b5 PF00173.28 CEG47574.1 - 4.1e-12 46.1 0.0 6.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aminotran_5 PF00266.19 CEG47580.1 - 0.088 11.7 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class-V Phage_fiber_2 PF03406.13 CEG47581.1 - 0.033 13.7 1.4 0.11 12.1 1.4 1.8 1 0 0 1 1 1 0 Phage tail fibre repeat HgmA PF04209.13 CEG47582.1 - 2.2e-106 356.1 0.9 5.7e-55 186.7 0.2 2.3 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Glyco_hydro81C PF17652.1 CEG47585.1 - 1.7e-108 363.0 0.4 2.4e-108 362.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEG47585.1 - 3.1e-36 125.2 1.6 3.5e-36 125.0 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Glutaredoxin2_C PF04399.13 CEG47587.1 - 1.1e-47 161.1 0.1 1.4e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 CEG47587.1 - 0.00028 21.3 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain cobW PF02492.19 CEG47588.1 - 2.8e-53 180.1 0.3 4e-53 179.6 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEG47588.1 - 1.8e-19 69.4 0.0 3.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CEG47588.1 - 5.4e-05 23.2 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG47588.1 - 0.0017 17.9 0.2 0.58 9.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEG47588.1 - 0.0052 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CEG47588.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEG47588.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CEG47588.1 - 0.049 12.7 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CEG47588.1 - 0.065 13.4 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEG47588.1 - 0.066 13.8 1.2 0.17 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEG47588.1 - 0.067 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 CEG47588.1 - 0.081 11.9 0.3 3.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 CEG47588.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 CEG47588.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Frag1 PF10277.9 CEG47589.1 - 6.7e-17 61.8 7.4 1.2e-16 61.0 7.4 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Sigma_reg_N PF13800.6 CEG47589.1 - 6.4 7.1 9.6 3.8 7.9 0.1 3.9 6 0 0 6 6 6 0 Sigma factor regulator N-terminal zinc_ribbon_10 PF10058.9 CEG47591.1 - 0.041 13.6 0.4 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MgsA_C PF12002.8 CEG47591.1 - 0.043 13.7 1.9 0.071 13.1 0.1 2.0 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal WW PF00397.26 CEG47592.1 - 2.8e-07 30.5 0.4 6e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 WW domain PsbP PF01789.16 CEG47592.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 PsbP PQQ PF01011.21 CEG47592.1 - 0.12 12.4 0.3 0.58 10.2 0.1 2.1 1 1 1 2 2 2 0 PQQ enzyme repeat zf-RING_7 PF02591.15 CEG47592.1 - 0.25 11.6 2.6 0.7 10.1 1.3 2.3 2 1 0 2 2 2 0 C4-type zinc ribbon domain APG6 PF04111.12 CEG47593.1 - 3.9e-60 202.9 0.0 7e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CEG47593.1 - 3.7e-16 59.8 0.1 3.7e-16 59.8 0.1 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region Aminotran_5 PF00266.19 CEG47594.1 - 8.7e-61 205.9 1.2 1.3e-60 205.4 1.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Mito_carr PF00153.27 CEG47595.1 - 1.9e-10 40.5 0.1 2.3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein WD40 PF00400.32 CEG47596.1 - 5e-35 118.9 18.3 2.8e-09 37.4 2.3 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG47596.1 - 3.9e-11 43.1 0.6 0.36 11.1 0.0 5.9 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG47596.1 - 7.4e-06 24.9 3.0 0.048 12.3 0.1 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Frtz PF11768.8 CEG47596.1 - 0.023 13.0 0.0 0.038 12.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CEG47596.1 - 0.03 13.3 0.6 7.9 5.3 0.0 4.0 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEG47596.1 - 0.19 11.6 0.2 2.1 8.2 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.32 CEG47597.1 - 1.2e-32 109.0 12.8 1.2e-09 37.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG47597.1 - 2.8e-29 101.4 7.2 1.6e-14 54.1 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG47597.1 - 4.1e-27 91.8 8.0 5.8e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEG47597.1 - 8.3e-21 72.5 11.0 1.9e-06 27.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEG47597.1 - 8.6e-20 70.3 13.1 1.3e-07 31.4 0.5 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CEG47597.1 - 9.6e-10 38.7 0.4 2.7e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEG47597.1 - 8.1e-07 29.0 5.2 0.018 15.0 0.5 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEG47597.1 - 4e-05 23.9 0.7 0.21 11.9 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CEG47597.1 - 7.7e-05 23.0 1.8 0.0073 16.6 0.4 2.4 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 CEG47597.1 - 0.0041 17.1 0.9 1.4 8.8 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein AAA_assoc_C PF09821.9 CEG47597.1 - 0.013 16.1 0.2 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal AAA-associated domain FGAR-AT_linker PF18072.1 CEG47597.1 - 0.021 15.4 0.0 2.4 8.7 0.0 2.5 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Acetyltransf_11 PF13720.6 CEG47597.1 - 0.026 15.0 0.1 0.33 11.4 0.0 2.3 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SurA_N_2 PF13623.6 CEG47597.1 - 0.032 14.1 3.0 0.34 10.8 0.7 2.6 1 1 1 2 2 2 0 SurA N-terminal domain SpoU_methylas_C PF12105.8 CEG47597.1 - 0.034 13.9 1.6 0.05 13.3 0.2 2.0 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal PMBR PF09373.10 CEG47597.1 - 0.042 14.0 0.1 27 5.2 0.0 3.8 3 1 1 4 4 4 0 Pseudomurein-binding repeat SUB1_ProdP9 PF18213.1 CEG47597.1 - 0.054 13.3 0.7 0.12 12.2 0.1 1.8 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 DUF3349 PF11829.8 CEG47597.1 - 0.06 14.1 0.7 15 6.4 0.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) IF2_N PF04760.15 CEG47597.1 - 0.077 12.8 2.0 27 4.7 0.0 3.9 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region DUF3008 PF11450.8 CEG47597.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.0 2 0 0 2 2 1 0 Protein of unknwon function (DUF3008) LETM1 PF07766.13 CEG47597.1 - 0.13 11.6 1.2 0.45 9.8 1.0 2.0 1 1 1 2 2 2 0 LETM1-like protein Toprim_2 PF13155.6 CEG47597.1 - 0.29 11.6 2.8 8.7 6.9 1.9 3.0 1 1 2 3 3 3 0 Toprim-like Skp1 PF01466.19 CEG47597.1 - 0.53 10.4 3.4 17 5.6 0.1 2.7 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DTHCT PF08070.11 CEG47598.1 - 1.7 9.4 5.6 0.84 10.4 1.0 2.8 2 1 0 2 2 2 0 DTHCT (NUC029) region RrnaAD PF00398.20 CEG47599.1 - 2e-36 125.4 0.3 1.7e-23 83.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CEG47599.1 - 0.00026 21.7 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG47599.1 - 0.00039 21.1 0.0 0.0008 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CEG47599.1 - 0.0029 16.7 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 CEG47599.1 - 0.0041 16.9 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG47599.1 - 0.0079 16.8 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG47599.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 CEG47599.1 - 0.025 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESX-1_EspG PF14011.6 CEG47599.1 - 0.039 13.6 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 EspG family PCMT PF01135.19 CEG47599.1 - 0.052 13.3 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEG47599.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ATF7IP_BD PF16788.5 CEG47605.1 - 0.17 11.9 9.7 0.94 9.5 0.1 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain CorA PF01544.18 CEG47607.1 - 2.5e-52 178.0 2.1 6.6e-43 147.1 1.1 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_7 PF13499.6 CEG47607.1 - 0.039 14.4 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair NTP_transf_2 PF01909.23 CEG47612.1 - 2.1e-08 34.3 0.0 5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEG47612.1 - 8.9e-08 32.2 0.0 2.5e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.6 CEG47612.1 - 0.0055 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm tRNA_NucTransf2 PF09249.11 CEG47612.1 - 0.019 15.2 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 CEG47612.1 - 0.042 13.9 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF547 PF04784.14 CEG47613.1 - 1e-22 80.5 0.0 3.7e-22 78.7 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF547 PH PF00169.29 CEG47613.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 PH domain PCO_ADO PF07847.12 CEG47614.1 - 8.5e-31 107.0 0.0 1.5e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 CEG47614.1 - 0.032 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Pirin PF02678.16 CEG47614.1 - 0.071 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Pirin EF-hand_7 PF13499.6 CEG47618.1 - 9.4e-27 93.3 5.1 1.5e-06 28.5 0.0 7.1 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 CEG47618.1 - 1.4e-24 83.8 6.1 0.00067 19.4 0.1 9.0 9 0 0 9 9 9 6 EF-hand domain EF-hand_1 PF00036.32 CEG47618.1 - 5.1e-23 78.8 1.2 0.00067 19.0 0.0 8.5 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 CEG47618.1 - 3.9e-19 68.2 0.6 0.0028 17.4 0.0 7.2 6 1 1 7 7 7 3 EF-hand domain pair EF-hand_5 PF13202.6 CEG47618.1 - 1.7e-09 36.7 3.1 0.03 13.8 0.0 6.9 8 0 0 8 8 8 3 EF hand Dzip-like_N PF13815.6 CEG47618.1 - 6.5e-09 35.8 0.7 6.5e-09 35.8 0.7 4.4 4 1 0 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal IQ PF00612.27 CEG47618.1 - 0.11 12.3 0.8 0.36 10.7 0.8 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2691 PF10903.8 CEG47619.1 - 0.0049 16.7 1.1 0.0049 16.7 1.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2691) Tubulin_C PF03953.17 CEG47619.1 - 0.56 10.4 2.8 0.57 10.3 0.1 2.5 3 0 0 3 3 3 0 Tubulin C-terminal domain Pox_A_type_inc PF04508.12 CEG47619.1 - 1 9.3 5.0 7.8 6.5 0.5 4.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Ig_4 PF16680.5 CEG47619.1 - 4.7 7.5 10.3 5.8 7.2 3.4 3.0 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain PLAC8 PF04749.17 CEG47621.1 - 5.3e-38 130.0 22.5 2.5e-19 70.1 5.7 2.5 2 0 0 2 2 2 2 PLAC8 family FixQ PF05545.11 CEG47621.1 - 0.0078 16.2 1.7 4.4 7.4 0.2 2.7 2 0 0 2 2 2 2 Cbb3-type cytochrome oxidase component FixQ DUF1364 PF07102.12 CEG47621.1 - 0.12 12.3 5.5 0.74 9.7 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) MFS_1 PF07690.16 CEG47621.1 - 0.17 10.8 8.5 0.18 10.7 0.7 2.5 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF3671 PF12420.8 CEG47621.1 - 0.33 11.0 1.3 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function SBF PF01758.16 CEG47621.1 - 0.39 10.4 3.9 0.43 10.2 0.3 2.2 2 0 0 2 2 2 0 Sodium Bile acid symporter family DUF4131 PF13567.6 CEG47621.1 - 1.4 8.5 12.0 0.84 9.3 1.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UMPH-1 PF05822.12 CEG47623.1 - 8.8e-73 244.8 0.5 1.1e-72 244.6 0.5 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CEG47623.1 - 4.4e-05 24.0 0.0 8.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PTPLA PF04387.14 CEG47624.1 - 2.3e-18 66.5 3.9 2.5e-18 66.3 3.9 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF3987 PF13148.6 CEG47624.1 - 0.14 11.1 0.2 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GLTP PF08718.11 CEG47626.1 - 6.4e-23 81.7 0.0 1.6e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FYVE PF01363.21 CEG47626.1 - 1.1e-10 41.5 11.7 3e-10 40.1 11.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG47626.1 - 7.8e-05 22.9 2.6 0.00025 21.2 2.6 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger Bd3614-deam PF14439.6 CEG47626.1 - 0.013 15.6 0.6 0.026 14.6 0.6 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase Bax1-I PF01027.20 CEG47627.1 - 4e-05 23.5 26.5 5e-05 23.2 26.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Nicastrin PF05450.15 CEG47628.1 - 2.9e-21 76.0 0.3 1.1e-20 74.1 0.3 1.8 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 CEG47628.1 - 7.4e-18 65.1 0.0 1.5e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 CEG47628.1 - 5.4e-10 39.3 0.1 2.1e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M28 DIM PF08194.12 CEG47628.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.8 3 0 0 3 3 3 0 DIM protein DUF1515 PF07439.11 CEG47629.1 - 0.22 11.6 2.3 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) PIG-L PF02585.17 CEG47630.1 - 2.3e-22 80.0 0.0 4.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Exostosin PF03016.15 CEG47630.1 - 5.7e-05 22.5 0.1 0.025 13.8 0.1 2.1 2 0 0 2 2 2 2 Exostosin family Ferrochelatase PF00762.19 CEG47631.1 - 8.5e-88 294.5 0.1 5.5e-87 291.8 0.1 2.1 2 1 1 3 3 3 1 Ferrochelatase CbiX PF01903.17 CEG47631.1 - 0.0016 18.7 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 CbiX TRAPP PF04051.16 CEG47632.1 - 6.1e-40 136.3 0.0 7.1e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pkinase PF00069.25 CEG47633.1 - 2.7e-36 125.3 0.0 2.6e-32 112.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47633.1 - 6.4e-34 117.4 0.0 8.6e-30 103.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 CEG47633.1 - 2.3e-09 37.3 11.8 0.00042 20.7 1.5 4.6 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG47633.1 - 2.3e-08 33.7 11.3 0.00012 21.7 1.4 4.5 4 1 1 5 5 5 4 Leucine rich repeat FNIP PF05725.12 CEG47633.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 FNIP Repeat LRR_9 PF14580.6 CEG47633.1 - 0.072 12.6 2.6 0.4 10.2 0.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Pkinase_fungal PF17667.1 CEG47633.1 - 0.074 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 CEG47633.1 - 7 7.0 14.3 2.2 8.5 1.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 CEG47634.1 - 9.1e-47 159.6 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47634.1 - 5.1e-44 150.5 0.0 7.3e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG47634.1 - 0.00024 20.8 2.4 0.02 14.7 0.8 3.7 3 1 0 3 3 3 1 Leucine rich repeat FNIP PF05725.12 CEG47634.1 - 0.0035 17.5 0.7 0.008 16.3 0.1 2.0 2 0 0 2 2 2 1 FNIP Repeat LRR_4 PF12799.7 CEG47634.1 - 0.005 17.2 6.0 2 9.0 0.8 4.7 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 CEG47634.1 - 0.0092 14.8 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PX PF00787.24 CEG47637.1 - 4.9e-05 23.3 0.1 7.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 CEG47638.1 - 0.00039 20.4 0.3 0.00059 19.8 0.3 1.3 1 0 0 1 1 1 1 PX domain EcpB_C PF18649.1 CEG47638.1 - 0.047 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain Atypical_Card PF18461.1 CEG47638.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.6 1 1 0 1 1 1 0 Atypical caspase recruitment domain IFT43 PF15305.6 CEG47642.1 - 2.7e-36 124.7 3.5 2.7e-36 124.7 3.5 1.6 2 0 0 2 2 2 1 Intraflagellar transport protein 43 DUF866 PF05907.13 CEG47643.1 - 4.8e-36 124.0 0.0 5.4e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4091 PF13320.6 CEG47644.1 - 8.8e-17 61.0 0.2 1.8e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4091) LpxC PF03331.13 CEG47645.1 - 7.1e-89 297.9 0.0 8.1e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Arylsulfotrans PF05935.11 CEG47645.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Cellulase PF00150.18 CEG47646.1 - 3.4e-30 105.4 0.0 4.1e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EGF_2 PF07974.13 CEG47646.1 - 0.012 16.0 17.5 0.012 16.0 17.5 3.7 3 0 0 3 3 3 0 EGF-like domain DUF5126 PF17166.4 CEG47646.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Rrp15p PF07890.12 CEG47648.1 - 1.3e-24 87.1 10.2 1.3e-24 87.1 10.2 2.3 2 0 0 2 2 2 1 Rrp15p TPR_1 PF00515.28 CEG47649.1 - 3.5e-24 83.6 11.3 7.4e-05 22.4 0.1 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 CEG47649.1 - 8.2e-22 77.1 2.3 1.4e-21 76.4 0.8 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CEG47649.1 - 2.8e-16 58.3 24.1 0.00034 20.5 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG47649.1 - 2.2e-08 33.6 9.1 0.14 12.4 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG47649.1 - 8.2e-07 29.4 22.5 0.25 11.9 0.1 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEG47649.1 - 9.8e-07 29.1 21.5 1.4 9.9 0.1 8.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG47649.1 - 2.2e-06 27.2 5.6 0.0036 16.9 0.2 5.2 6 1 0 6 6 6 2 TPR repeat TPR_7 PF13176.6 CEG47649.1 - 2.4e-05 24.1 10.8 0.12 12.5 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG47649.1 - 2.8e-05 24.2 2.1 0.082 13.3 0.0 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG47649.1 - 3.2e-05 24.0 11.1 0.0017 18.4 3.7 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 CEG47649.1 - 0.0004 20.4 7.6 0.38 10.9 0.2 4.0 3 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 CEG47649.1 - 0.0048 17.5 23.3 0.016 15.8 0.1 6.1 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG47649.1 - 0.0053 17.0 26.7 0.29 11.5 1.1 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG47649.1 - 0.036 14.3 11.2 15 5.9 0.4 5.0 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 CEG47649.1 - 0.078 13.0 0.4 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG47649.1 - 0.57 10.9 14.4 4.5 8.1 0.1 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG47649.1 - 1.7 8.6 14.8 0.8 9.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DSPc PF00782.20 CEG47650.1 - 8.8e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CEG47650.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 CEG47650.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CEG47650.1 - 0.0027 17.8 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CEG47650.1 - 0.0047 16.5 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MRG PF05712.13 CEG47651.1 - 1.3e-46 158.4 0.5 2e-46 157.8 0.5 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CEG47651.1 - 1.1e-08 34.8 1.4 2.3e-08 33.8 1.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PLAC8 PF04749.17 CEG47653.1 - 3e-16 60.2 4.4 3.8e-16 59.9 4.4 1.1 1 0 0 1 1 1 1 PLAC8 family GATase_2 PF00310.21 CEG47654.1 - 2.4e-159 530.6 0.0 3.2e-159 530.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CEG47654.1 - 2.4e-153 510.6 0.2 3.4e-150 500.3 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CEG47654.1 - 4.7e-106 354.3 0.0 8.4e-106 353.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 CEG47654.1 - 2.8e-76 255.4 6.3 5.2e-76 254.5 6.3 1.4 1 0 0 1 1 1 1 GXGXG motif HSF_DNA-bind PF00447.17 CEG47654.1 - 0.16 12.6 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 HSF-type DNA-binding Corona_nucleoca PF00937.18 CEG47656.1 - 0.17 10.9 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RVT_1 PF00078.27 CEG47657.1 - 1.4e-09 37.8 0.2 1.8e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NHL PF01436.21 CEG47657.1 - 1.5e-07 31.1 0.1 3.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 NHL repeat Arylesterase PF01731.20 CEG47657.1 - 0.01 16.0 0.1 0.024 14.8 0.0 1.7 2 0 0 2 2 2 0 Arylesterase RtxA PF07634.11 CEG47658.1 - 0.11 13.0 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 RtxA repeat ATP-grasp_2 PF08442.10 CEG47659.1 - 1.2e-64 217.6 1.5 2.3e-64 216.7 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CEG47659.1 - 1.4e-22 80.2 1.5 2.4e-22 79.4 1.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CEG47659.1 - 1.3e-08 34.6 1.3 1.9e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Peripla_BP_4 PF13407.6 CEG47659.1 - 0.008 15.8 0.8 0.018 14.6 0.8 1.6 1 0 0 1 1 1 1 Periplasmic binding protein domain Arf PF00025.21 CEG47660.1 - 8.3e-71 237.0 0.3 9.4e-71 236.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CEG47660.1 - 7.8e-15 54.9 0.9 3e-10 39.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CEG47660.1 - 2.4e-13 50.0 0.0 2.8e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEG47660.1 - 3.5e-13 49.4 0.0 4.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CEG47660.1 - 8.5e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CEG47660.1 - 5e-10 39.1 0.0 5.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG47660.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG47660.1 - 0.0003 20.4 0.0 0.0031 17.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CEG47660.1 - 0.019 15.5 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CEG47660.1 - 0.021 15.2 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CEG47660.1 - 0.028 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PAE PF03283.13 CEG47660.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase RNA_pol_Rpb4 PF03874.16 CEG47664.1 - 6.6e-18 65.2 1.6 1e-17 64.6 1.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4922 PF16269.5 CEG47664.1 - 0.0051 16.6 0.1 0.0056 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4313 PF14190.6 CEG47664.1 - 0.042 13.9 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) KicB PF03882.14 CEG47664.1 - 0.048 13.9 0.4 0.1 12.8 0.2 1.6 2 0 0 2 2 2 0 MukF winged-helix domain DUF3140 PF11338.8 CEG47664.1 - 0.092 13.2 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) CagY_M PF07337.11 CEG47664.1 - 1.2 8.8 4.2 2 8.1 0.2 2.7 3 0 0 3 3 3 0 DC-EC Repeat ATP12 PF07542.11 CEG47665.1 - 2.9e-34 117.9 0.4 4.5e-34 117.3 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein ATP-synt_ab PF00006.25 CEG47667.1 - 1.8e-22 80.1 0.0 3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 CEG47667.1 - 0.011 16.0 0.0 0.066 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain CUE PF02845.16 CEG47668.1 - 1.6e-06 27.7 0.4 4.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 CUE domain T2SSJ PF11612.8 CEG47669.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J XRCC1_N PF01834.16 CEG47672.1 - 0.077 13.0 0.1 0.3 11.1 0.0 2.1 1 1 0 2 2 2 0 XRCC1 N terminal domain F5_F8_type_C PF00754.25 CEG47672.1 - 0.092 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Microcephalin PF12258.8 CEG47672.1 - 0.096 11.9 2.0 0.14 11.4 1.2 1.8 2 1 0 2 2 2 0 Microcephalin protein RdRP PF05183.12 CEG47673.1 - 6e-147 490.8 0.0 8.5e-147 490.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 CEG47673.1 - 3.6e-16 59.5 0.0 1.8e-15 57.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG47673.1 - 2.7e-12 47.0 0.0 8.6e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG47673.1 - 3.4e-12 46.5 0.0 9.7e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CEG47673.1 - 0.02 14.1 0.0 0.08 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTP_transf_2 PF01909.23 CEG47673.1 - 0.042 14.1 0.1 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Nucleotidyltransferase domain ShlB PF03865.13 CEG47673.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB PH PF00169.29 CEG47675.1 - 0.0043 17.5 0.0 0.02 15.4 0.0 2.2 2 0 0 2 2 2 1 PH domain CLAMP PF14769.6 CEG47676.1 - 6e-18 65.1 1.2 8.5e-18 64.6 1.2 1.3 1 1 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Myb_DNA-bind_6 PF13921.6 CEG47676.1 - 0.0051 17.0 0.1 0.082 13.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Amidohydro_3 PF07969.11 CEG47677.1 - 6.6e-88 296.2 0.0 7.7e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Rep_fac-A_3 PF08661.11 CEG47677.1 - 1.3e-14 54.5 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor A protein 3 Amidohydro_1 PF01979.20 CEG47677.1 - 2.3e-09 37.1 0.0 2.2e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Retrotrans_gag PF03732.17 CEG47678.1 - 0.025 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_hydr_30_2 PF14587.6 CEG47681.1 - 3.2e-22 79.7 5.4 9.1e-22 78.1 5.4 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 CEG47681.1 - 1.5e-09 37.5 0.3 2.6e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 HPIH PF13323.6 CEG47681.1 - 0.09 12.6 0.9 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain with HPIH motif SfsA PF03749.13 CEG47682.1 - 1.1e-33 116.1 0.2 3.6e-33 114.4 0.2 1.8 1 1 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 CEG47682.1 - 2.4e-17 62.8 0.0 4.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain POM121 PF15229.6 CEG47682.1 - 0.15 11.7 5.4 0.25 11.0 5.4 1.3 1 0 0 1 1 1 0 POM121 family Sec66 PF09802.9 CEG47683.1 - 1.1e-09 38.1 1.2 1.1e-09 38.1 1.2 1.5 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4192 PF13830.6 CEG47683.1 - 0.00055 20.1 0.3 0.00056 20.1 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4192) MitoNEET_N PF10660.9 CEG47683.1 - 0.078 13.0 0.2 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus KfrA_N PF11740.8 CEG47683.1 - 0.23 12.2 12.5 0.48 11.1 12.5 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term ApoO PF09769.9 CEG47683.1 - 0.9 9.5 4.2 8.2 6.4 1.5 2.7 2 1 0 2 2 2 0 Apolipoprotein O DUF4524 PF15025.6 CEG47684.1 - 2.7e-15 56.4 0.1 7.3e-12 45.3 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4524) DUF4520 PF15016.6 CEG47684.1 - 6e-10 39.1 0.1 3.5e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) Tombus_P33 PF08500.10 CEG47684.1 - 0.11 12.5 0.4 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Tombusvirus p33 RRM_1 PF00076.22 CEG47685.1 - 2.5e-08 33.6 0.0 6.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MORN PF02493.20 CEG47688.1 - 1.1e-16 59.6 32.8 5e-05 23.0 1.2 8.5 9 0 0 9 9 9 6 MORN repeat LRR_6 PF13516.6 CEG47688.1 - 3.7e-07 29.7 19.5 10 6.5 0.0 11.5 12 0 0 12 12 12 2 Leucine Rich repeat WW PF00397.26 CEG47688.1 - 2.5e-06 27.5 6.8 1.8e-05 24.7 1.9 2.6 2 0 0 2 2 2 1 WW domain IQ PF00612.27 CEG47688.1 - 0.00026 20.5 1.2 0.00026 20.5 1.2 8.4 8 0 0 8 8 8 5 IQ calmodulin-binding motif OST-HTH PF12872.7 CEG47688.1 - 0.0039 17.0 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 OST-HTH/LOTUS domain LRR_4 PF12799.7 CEG47688.1 - 0.0048 17.3 27.6 2.3 8.8 0.0 8.5 8 2 2 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG47688.1 - 3.4 7.5 12.1 0.11 12.3 1.0 4.1 3 1 1 4 4 4 0 Leucine rich repeat AAA_16 PF13191.6 CEG47690.1 - 9.9e-05 22.8 0.1 0.0003 21.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 CEG47690.1 - 0.00022 21.0 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 CEG47690.1 - 0.00025 20.3 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 CEG47690.1 - 0.00071 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEG47690.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CEG47690.1 - 0.0028 17.4 0.0 0.0079 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEG47690.1 - 0.0033 17.9 0.0 0.0083 16.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 CEG47690.1 - 0.0035 17.8 0.0 0.0091 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CEG47690.1 - 0.0039 17.1 0.1 0.14 12.0 0.0 2.8 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.12 CEG47690.1 - 0.0057 16.0 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CEG47690.1 - 0.0072 16.5 0.3 0.028 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CEG47690.1 - 0.0093 15.9 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 CEG47690.1 - 0.012 15.9 3.7 0.012 15.9 0.0 2.8 4 1 0 4 4 2 0 AAA domain cobW PF02492.19 CEG47690.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 CEG47690.1 - 0.016 14.6 0.9 0.078 12.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.17 CEG47690.1 - 0.018 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 CEG47690.1 - 0.021 15.1 0.1 0.062 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CEG47690.1 - 0.021 14.3 0.5 0.042 13.3 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CEG47690.1 - 0.025 14.1 0.0 0.078 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEG47690.1 - 0.026 14.5 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 CEG47690.1 - 0.03 13.8 0.1 0.67 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TrwB_AAD_bind PF10412.9 CEG47690.1 - 0.033 13.1 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 CEG47690.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CEG47690.1 - 0.055 12.7 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 CEG47690.1 - 0.059 12.5 0.2 0.24 10.5 0.0 2.0 3 0 0 3 3 3 0 G-protein alpha subunit AAA_3 PF07726.11 CEG47690.1 - 0.061 13.2 0.0 0.58 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 CEG47690.1 - 0.064 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 CEG47690.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CEG47690.1 - 0.11 12.3 0.3 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CEG47690.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEG47690.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF1_GNE PF00736.19 CEG47691.1 - 2.7e-32 110.8 1.5 5.4e-32 109.8 1.5 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CEG47691.1 - 0.00025 21.4 10.8 0.00073 19.9 10.8 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region DUF3381 PF11861.8 CEG47691.1 - 0.0015 18.4 1.0 0.0022 17.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Stm1_N PF09598.10 CEG47691.1 - 0.028 15.3 3.6 0.028 15.3 3.6 1.6 2 0 0 2 2 2 0 Stm1 OmpA PF00691.20 CEG47691.1 - 0.046 14.1 0.2 0.083 13.3 0.2 1.5 1 0 0 1 1 1 0 OmpA family PBP1_TM PF14812.6 CEG47691.1 - 0.11 12.9 4.5 0.18 12.2 4.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA_m1G_MT PF01746.21 CEG47692.1 - 4.7e-23 81.9 0.1 1.5e-22 80.3 0.0 1.9 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase PEHE PF15275.6 CEG47692.1 - 2.1 9.0 6.7 0.85 10.3 2.6 2.1 2 0 0 2 2 2 0 PEHE domain Nucleoside_tran PF01733.18 CEG47694.1 - 9.1e-50 169.8 7.0 9.1e-50 169.8 7.0 2.0 1 1 1 2 2 2 1 Nucleoside transporter Pex24p PF06398.11 CEG47694.1 - 5.7 5.8 9.9 8.3 5.3 3.9 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Bud13 PF09736.9 CEG47695.1 - 1.5e-16 61.1 21.3 5.1e-14 52.9 13.1 5.8 4 2 1 5 5 5 2 Pre-mRNA-splicing factor of RES complex FBPase PF00316.20 CEG47696.1 - 4.9e-69 231.6 0.2 6.3e-69 231.2 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CEG47696.1 - 0.00065 19.3 0.0 0.0013 18.4 0.0 1.4 2 0 0 2 2 2 1 Inositol monophosphatase family Aldedh PF00171.22 CEG47702.1 - 8e-182 604.9 0.0 9.1e-182 604.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_4 PF13562.6 CEG47702.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Spectrin_like PF18373.1 CEG47703.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Spectrin like domain MULE PF10551.9 CEG47704.1 - 2.4e-09 37.5 0.4 7.4e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 CEG47704.1 - 2.2e-05 24.0 0.3 4.9e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.18 CEG47704.1 - 0.0033 16.3 0.1 0.0055 15.6 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Pkinase PF00069.25 CEG47706.1 - 1.7e-62 211.2 0.0 1.5e-61 208.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG47706.1 - 1.8e-31 109.4 0.0 3.2e-25 88.9 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase PAS PF00989.25 CEG47706.1 - 9.5e-08 32.0 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CEG47706.1 - 0.0014 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain Kdo PF06293.14 CEG47706.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 CEG47706.1 - 0.026 14.8 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 CEG47706.1 - 0.026 14.5 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS domain APH PF01636.23 CEG47706.1 - 0.029 14.3 0.3 0.061 13.2 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rz1 PF06085.11 CEG47706.1 - 0.043 13.6 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor Mlh1_C PF16413.5 CEG47707.1 - 7.9e-69 232.0 0.5 7.9e-69 232.0 0.5 3.3 2 2 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CEG47707.1 - 3.3e-32 110.6 0.0 7.6e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEG47707.1 - 2.2e-12 47.0 0.0 6.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEG47707.1 - 5.5e-08 33.3 0.1 1.4e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOC PF07744.13 CEG47708.1 - 2e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain Peptidase_M24 PF00557.24 CEG47709.1 - 3.8e-46 157.4 0.0 5.5e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEG47709.1 - 4.7e-37 126.5 0.0 7.9e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribosomal_S8e PF01201.22 CEG47710.1 - 1.1e-49 168.2 6.6 1.7e-47 161.0 6.6 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e CDPS PF16715.5 CEG47710.1 - 1.5 8.5 5.2 2.5 7.7 4.7 1.6 2 0 0 2 2 2 0 Cyclodipeptide synthase tRNA-synt_His PF13393.6 CEG47713.1 - 2.3e-42 145.4 0.7 1.5e-41 142.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 CEG47713.1 - 5.7e-22 78.0 0.3 1e-21 77.2 0.3 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase tRNA-synt_2 PF00152.20 CEG47713.1 - 0.00085 18.5 0.0 0.00085 18.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 CEG47713.1 - 0.0053 16.3 4.4 0.0077 15.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs DUF737 PF05300.11 CEG47713.1 - 0.037 14.4 3.0 0.062 13.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) RNA_pol_Rpc4 PF05132.14 CEG47713.1 - 0.14 12.5 0.6 0.4 11.1 0.5 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 TMF_TATA_bd PF12325.8 CEG47713.1 - 0.74 10.0 8.2 1.5 9.1 8.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Aldedh PF00171.22 CEG47713.1 - 2.6 6.4 5.2 4.4 5.7 5.2 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DUF1682 PF07946.14 CEG47713.1 - 2.7 7.1 11.6 4.6 6.4 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4535 PF15054.6 CEG47716.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Aldedh PF00171.22 CEG47717.1 - 2.5e-135 451.6 0.3 2.8e-135 451.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CEG47717.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Gly-zipper_YMGG PF13441.6 CEG47717.1 - 0.11 12.2 3.4 0.29 10.9 3.4 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper GLE1 PF07817.13 CEG47718.1 - 4.8e-48 163.6 0.1 4.8e-48 163.6 0.1 2.1 2 0 0 2 2 2 1 GLE1-like protein DUF4507 PF14964.6 CEG47718.1 - 0.0012 17.8 2.0 0.0017 17.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4507) Ribosomal_S27e PF01667.17 CEG47719.1 - 3.6e-28 97.0 4.3 4.6e-28 96.7 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 CEG47719.1 - 0.11 12.9 3.2 0.66 10.4 3.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-CSL PF05207.13 CEG47719.1 - 0.12 12.1 2.6 0.25 11.1 2.6 1.6 1 1 0 1 1 1 0 CSL zinc finger Arm PF00514.23 CEG47720.1 - 2.1e-54 180.0 27.6 4.1e-12 45.7 0.0 9.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEG47720.1 - 8.8e-18 64.4 5.1 4.3e-08 33.5 0.1 5.6 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 CEG47720.1 - 3.2e-13 49.9 4.1 2.2e-05 24.7 0.0 5.3 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CEG47720.1 - 1.4e-10 40.5 10.1 0.29 11.5 0.0 7.8 8 0 0 8 8 7 3 HEAT repeat NopRA1 PF16201.5 CEG47720.1 - 8.4e-07 28.8 0.1 0.0042 16.7 0.0 3.5 3 1 0 3 3 3 2 Nucleolar pre-ribosomal-associated protein 1 Arm_2 PF04826.13 CEG47720.1 - 2.3e-05 24.0 0.2 0.064 12.7 0.0 3.2 2 1 1 3 3 3 2 Armadillo-like Arm_3 PF16186.5 CEG47720.1 - 4e-05 23.1 0.0 0.27 10.8 0.0 2.9 2 0 0 2 2 2 2 Atypical Arm repeat V-ATPase_H_C PF11698.8 CEG47720.1 - 0.0011 19.1 0.0 0.64 10.1 0.0 4.1 4 0 0 4 4 4 1 V-ATPase subunit H DUF3361 PF11841.8 CEG47720.1 - 0.0011 19.0 0.0 0.88 9.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) FYVE_2 PF02318.16 CEG47720.1 - 0.012 15.9 8.4 0.032 14.4 8.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger RICTOR_V PF14668.6 CEG47720.1 - 0.029 14.6 2.6 3.1 8.1 0.1 4.3 3 3 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 CNDH2_C PF16858.5 CEG47720.1 - 0.16 11.8 10.7 0.33 10.8 10.7 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PHC2_SAM_assoc PF16616.5 CEG47720.1 - 0.26 12.1 12.4 0.59 11.0 12.4 1.5 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 CTNNBL PF08216.11 CEG47720.1 - 0.29 11.3 7.1 8 6.7 0.0 4.8 6 0 0 6 6 5 0 Catenin-beta-like, Arm-motif containing nuclear EIIBC-GUT_N PF03612.14 CEG47720.1 - 0.67 9.7 3.8 6.8 6.4 1.6 2.7 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Nop25 PF09805.9 CEG47720.1 - 5.6 7.4 20.8 10 6.6 20.8 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) zf-RING_2 PF13639.6 CEG47721.1 - 2e-07 31.2 17.2 2e-07 31.2 17.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEG47721.1 - 1.4e-06 28.5 14.2 5.2e-06 26.6 14.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rootletin PF15035.6 CEG47721.1 - 0.00044 20.3 5.6 0.00064 19.8 5.2 1.4 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Angiomotin_C PF12240.8 CEG47721.1 - 0.00056 19.5 3.5 0.0012 18.5 3.5 1.4 1 0 0 1 1 1 1 Angiomotin C terminal zf-ANAPC11 PF12861.7 CEG47721.1 - 0.002 18.1 10.9 0.0065 16.5 10.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CEG47721.1 - 0.0045 16.8 17.0 0.013 15.3 17.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG47721.1 - 0.018 14.8 16.2 0.053 13.4 16.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG47721.1 - 0.022 14.6 17.3 0.07 13.0 17.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG47721.1 - 0.034 14.2 13.6 0.32 11.0 13.6 2.6 1 1 0 1 1 1 0 RING-type zinc-finger DUF573 PF04504.14 CEG47721.1 - 0.056 14.1 2.3 0.43 11.3 2.9 2.2 2 0 0 2 2 1 0 Protein of unknown function, DUF573 Prok-RING_4 PF14447.6 CEG47721.1 - 0.081 12.8 16.9 0.22 11.4 16.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GAGA PF09237.11 CEG47721.1 - 2.5 8.0 5.2 0.93 9.4 0.4 2.4 2 0 0 2 2 2 0 GAGA factor zf-RING_5 PF14634.6 CEG47721.1 - 3.5 7.7 20.8 0.43 10.6 16.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain AAA PF00004.29 CEG47722.1 - 3.5e-43 147.2 0.0 7.3e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CEG47722.1 - 1.3e-14 54.0 1.3 3.6e-14 52.6 1.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CEG47722.1 - 6.3e-10 38.7 0.0 1.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CEG47722.1 - 3.5e-06 27.5 0.9 5.8e-05 23.5 0.4 2.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEG47722.1 - 5.3e-06 26.8 0.8 0.002 18.4 0.7 3.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CEG47722.1 - 8.1e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 CEG47722.1 - 0.00011 22.1 0.5 0.0011 18.9 0.0 2.9 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CEG47722.1 - 0.00023 20.5 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CEG47722.1 - 0.00034 20.6 0.5 0.0042 17.1 0.5 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 CEG47722.1 - 0.00072 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_2 PF07724.14 CEG47722.1 - 0.001 19.2 0.1 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEG47722.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CEG47722.1 - 0.0014 19.1 0.0 0.005 17.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CEG47722.1 - 0.0034 17.6 0.1 0.0095 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEG47722.1 - 0.0076 16.6 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CEG47722.1 - 0.0088 15.4 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CEG47722.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CEG47722.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEG47722.1 - 0.018 14.5 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 CEG47722.1 - 0.025 14.2 0.9 0.21 11.2 0.2 2.3 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEG47722.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEG47722.1 - 0.039 14.2 0.2 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEG47722.1 - 0.039 13.3 0.3 0.89 8.9 0.1 2.3 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.27 CEG47722.1 - 0.043 14.3 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 CEG47722.1 - 0.046 14.1 0.3 0.26 11.7 0.0 2.4 3 1 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 CEG47722.1 - 0.053 13.2 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 CEG47722.1 - 0.085 12.8 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 CEG47722.1 - 0.12 12.1 0.3 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEG47722.1 - 0.14 11.9 0.2 0.37 10.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ProQ PF04352.13 CEG47722.1 - 0.14 12.0 1.9 0.35 10.8 1.9 1.6 1 0 0 1 1 1 0 ProQ/FINO family UCH PF00443.29 CEG47723.1 - 2.6e-28 99.2 0.3 3.7e-28 98.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEG47723.1 - 9.8e-15 54.6 2.4 1.8e-14 53.8 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CEG47723.1 - 0.0002 21.1 1.7 0.0025 17.5 0.2 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Armet PF10208.9 CEG47723.1 - 0.00061 19.7 0.3 0.0067 16.4 0.1 2.4 3 0 0 3 3 3 1 Degradation arginine-rich protein for mis-folding zf-UBP_var PF17807.1 CEG47723.1 - 0.094 12.5 0.9 0.29 10.9 0.4 2.0 2 0 0 2 2 2 0 Variant UBP zinc finger E1_dh PF00676.20 CEG47724.1 - 3e-105 351.5 0.9 3.7e-105 351.2 0.9 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CEG47724.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 CEG47724.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain gag-asp_proteas PF13975.6 CEG47725.1 - 0.0092 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HasA PF06438.12 CEG47725.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) NPV_P10 PF05531.12 CEG47726.1 - 0.04 14.4 0.7 0.04 14.4 0.7 6.4 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1515 PF07439.11 CEG47726.1 - 0.047 13.7 0.9 0.047 13.7 0.9 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF1515) LPP PF04728.13 CEG47726.1 - 0.057 13.8 19.7 12 6.3 0.8 6.2 4 1 0 4 4 4 0 Lipoprotein leucine-zipper YvfG PF09628.10 CEG47726.1 - 0.35 11.2 5.2 0.32 11.4 0.9 3.1 3 0 0 3 3 3 0 YvfG protein Surfac_D-trimer PF09006.11 CEG47726.1 - 1 9.3 6.0 19 5.2 0.2 4.5 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Seryl_tRNA_N PF02403.22 CEG47726.1 - 2.7 8.2 65.9 0.097 12.9 3.1 6.0 1 1 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain AA_permease_2 PF13520.6 CEG47728.1 - 1e-39 136.6 30.4 1e-39 136.6 30.4 2.6 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CEG47728.1 - 9.7e-25 87.1 25.8 9.7e-25 87.1 25.8 2.8 2 2 1 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 CEG47728.1 - 1.2e-13 50.9 8.9 1.2e-13 50.9 8.9 2.9 2 0 0 2 2 2 1 C-terminus of AA_permease DUF2615 PF11027.8 CEG47728.1 - 0.083 13.0 1.1 16 5.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) TRAP-gamma PF07074.12 CEG47728.1 - 0.089 12.3 0.9 0.3 10.6 0.9 1.9 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Sigma_reg_N PF13800.6 CEG47728.1 - 0.25 11.6 3.5 6.9 7.0 0.0 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PAN_4 PF14295.6 CEG47729.1 - 3e-09 36.7 5.6 9.9e-09 35.0 5.6 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CEG47729.1 - 0.00046 20.1 0.9 0.00046 20.1 0.9 2.2 2 0 0 2 2 2 1 PAN domain ABC2_membrane PF01061.24 CEG47730.1 - 1.3e-67 227.2 75.2 2.5e-39 134.9 27.2 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG47730.1 - 5.9e-36 124.0 0.0 1.2e-17 64.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEG47730.1 - 3e-09 36.6 7.2 2.6e-07 30.4 0.0 4.3 4 0 0 4 4 3 1 CDR ABC transporter AAA_21 PF13304.6 CEG47730.1 - 5.4e-08 33.0 0.6 0.011 15.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEG47730.1 - 4.1e-07 30.5 0.0 0.0055 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEG47730.1 - 9.3e-07 28.9 2.5 0.012 15.5 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEG47730.1 - 1.7e-05 24.5 5.9 0.024 14.4 0.8 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEG47730.1 - 2.2e-05 23.8 1.1 0.0024 17.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CEG47730.1 - 5e-05 23.6 0.5 0.092 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 CEG47730.1 - 0.00012 21.8 11.7 0.0067 16.2 0.6 3.6 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_25 PF13481.6 CEG47730.1 - 0.00013 21.6 0.3 0.64 9.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CEG47730.1 - 0.00019 20.9 2.6 7.7 5.9 0.0 4.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CEG47730.1 - 0.00052 19.2 58.5 0.01 15.0 28.6 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.6 CEG47730.1 - 0.0016 19.0 1.2 0.17 12.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG47730.1 - 0.0024 17.6 0.3 2.2 7.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEG47730.1 - 0.005 17.3 0.2 12 6.4 0.1 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG47730.1 - 0.0053 17.3 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEG47730.1 - 0.0056 16.7 0.0 0.39 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CEG47730.1 - 0.0059 16.7 1.4 0.95 9.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 CEG47730.1 - 0.016 15.3 2.6 1.2 9.2 0.0 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_24 PF13479.6 CEG47730.1 - 0.019 14.7 0.7 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CEG47730.1 - 0.025 14.8 0.8 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CEG47730.1 - 0.026 14.9 0.3 3.8 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 CEG47730.1 - 0.046 13.7 3.8 6.9 6.6 0.1 3.2 4 0 0 4 4 3 0 NACHT domain cobW PF02492.19 CEG47730.1 - 0.071 12.7 2.3 1.8 8.1 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 CEG47730.1 - 0.072 13.0 0.2 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 CEG47730.1 - 0.12 12.6 0.1 14 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEG47730.1 - 0.15 11.6 2.2 0.48 9.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CEG47730.1 - 0.26 11.0 1.3 5.2 6.8 0.4 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2575 PF10837.8 CEG47730.1 - 0.36 11.1 4.2 0.28 11.5 1.3 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2575) SPC25 PF06703.11 CEG47730.1 - 0.63 9.8 2.9 0.68 9.7 0.9 2.1 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ABC_ATPase PF09818.9 CEG47730.1 - 0.65 8.7 2.7 2.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 CEG47730.1 - 0.88 9.8 2.6 35 4.6 1.2 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEG47730.1 - 0.95 9.5 2.6 1.7 8.6 0.4 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tox-PLDMTX PF15645.6 CEG47731.1 - 0.16 12.2 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold adh_short PF00106.25 CEG47737.1 - 3.2e-33 114.8 0.8 6.5e-33 113.8 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG47737.1 - 4.9e-24 85.2 0.1 7.9e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG47737.1 - 0.00035 20.5 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG47737.1 - 0.0006 19.3 0.0 0.0007 19.1 0.0 1.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CEG47737.1 - 0.0058 16.6 0.1 0.017 15.1 0.0 1.8 1 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 CEG47737.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 CEG47737.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Cas_Csy4 PF09618.10 CEG47739.1 - 0.0022 18.2 0.1 12 6.0 0.0 3.1 1 1 2 3 3 3 2 CRISPR-associated protein (Cas_Csy4) Glycoprotein_B PF00606.18 CEG47739.1 - 0.066 12.6 0.4 6.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B ectodomain CXCR4_N PF12109.8 CEG47739.1 - 0.14 12.4 0.0 32 4.9 0.0 3.3 3 0 0 3 3 3 0 CXCR4 Chemokine receptor N terminal DUF594 PF04578.13 CEG47739.1 - 0.14 11.7 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF594 KI67R PF08065.12 CEG47739.1 - 3.2 8.3 12.9 5.6 7.6 2.1 2.6 2 0 0 2 2 2 0 KI67R (NUC007) repeat RPOL_N PF14700.6 CEG47739.1 - 4 6.7 8.4 2.7 7.3 3.1 2.5 1 1 2 3 3 3 0 DNA-directed RNA polymerase N-terminal zf-BED PF02892.15 CEG47740.1 - 4e-09 36.3 0.4 4e-09 36.3 0.4 1.7 2 0 0 2 2 2 1 BED zinc finger Adeno_E3_CR1 PF02440.15 CEG47740.1 - 0.15 11.9 0.1 0.63 9.9 0.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Lip_A_acyltrans PF03279.13 CEG47744.1 - 3.3e-32 111.8 0.0 3.8e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase PAP_assoc PF03828.19 CEG47752.1 - 2.6e-14 53.2 0.0 6.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEG47752.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-CCHC PF00098.23 CEG47752.1 - 0.003 17.5 4.7 0.003 17.5 4.7 2.5 2 0 0 2 2 2 1 Zinc knuckle Nrap_D2 PF17403.2 CEG47752.1 - 0.088 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain zf-CCHC_4 PF14392.6 CEG47752.1 - 6.6 6.6 14.9 2.2 8.1 7.1 2.5 2 0 0 2 2 2 0 Zinc knuckle Raf1_HTH PF18579.1 CEG47755.1 - 0.033 13.9 0.2 5.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain VPS13 PF16908.5 CEG47760.1 - 3.5e-27 95.7 0.7 7.4e-27 94.7 0.7 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CEG47760.1 - 1.9e-16 60.4 0.0 4.8e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CEG47760.1 - 2.2e-16 60.1 0.0 9.2e-12 44.9 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 CEG47760.1 - 2.3e-12 47.0 0.2 5.5e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 IQ PF00612.27 CEG47760.1 - 0.44 10.5 8.6 1 9.3 2.2 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif PDZ PF00595.24 CEG47761.1 - 8.2e-05 22.9 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG47761.1 - 0.037 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Methyltransf_1N PF02870.15 CEG47762.1 - 0.12 13.2 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain S10_plectin PF03501.15 CEG47766.1 - 2.2e-47 159.1 0.3 2.6e-47 158.8 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Mito_carr PF00153.27 CEG47767.1 - 5.9e-63 208.8 2.7 1.2e-20 73.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.15 CEG47767.1 - 0.1 12.8 1.7 16 5.6 0.0 2.4 1 1 1 2 2 2 0 Chromate transporter PT-VENN PF04829.13 CEG47767.1 - 1.3 9.1 4.1 12 6.1 0.1 2.9 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif ECH_1 PF00378.20 CEG47768.1 - 7.5e-44 149.9 0.2 2e-43 148.6 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEG47768.1 - 1.9e-25 90.1 0.3 1.9e-24 86.8 0.1 1.8 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF2525 PF10733.9 CEG47768.1 - 0.051 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) rve PF00665.26 CEG47770.1 - 5.5e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PAP2 PF01569.21 CEG47771.1 - 6.4e-23 81.0 1.4 6.4e-23 81.0 1.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CEG47771.1 - 0.00017 21.4 3.8 0.19 11.4 1.7 2.4 2 0 0 2 2 2 2 PAP2 superfamily EptA_B_N PF08019.12 CEG47771.1 - 0.075 12.9 0.4 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Phage_holin_5_1 PF06946.11 CEG47771.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Kelch_3 PF13415.6 CEG47772.1 - 8.9e-23 80.1 5.1 0.00075 19.7 0.1 7.1 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG47772.1 - 6.1e-20 70.5 6.8 0.00022 20.8 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CEG47772.1 - 5.8e-17 61.3 12.8 0.0014 18.6 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CEG47772.1 - 8.1e-17 60.9 9.8 0.0034 17.6 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CEG47772.1 - 1.7e-16 59.9 8.8 0.00032 20.7 0.0 6.5 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CEG47772.1 - 2.4e-15 55.8 11.1 0.011 15.7 0.1 6.7 6 1 0 6 6 6 6 Kelch motif Dehalogenase PF13486.6 CEG47774.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit TPR_11 PF13414.6 CEG47775.1 - 0.043 13.5 0.6 21 4.9 0.0 3.6 3 0 0 3 3 3 0 TPR repeat VPS9 PF02204.18 CEG47778.1 - 1.2e-13 51.2 0.0 2.7e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 CEG47778.1 - 0.052 13.5 0.3 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 PX domain Myb_DNA-binding PF00249.31 CEG47782.1 - 4e-32 110.2 7.0 3.4e-09 36.7 0.0 5.1 5 1 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG47782.1 - 1.3e-27 95.8 0.3 7.9e-08 32.4 0.0 4.7 2 1 3 5 5 5 4 Myb-like DNA-binding domain SLIDE PF09111.10 CEG47782.1 - 0.00016 21.7 0.0 0.022 14.8 0.0 3.5 2 1 1 3 3 3 1 SLIDE Sec66 PF09802.9 CEG47782.1 - 0.06 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 PseudoU_synth_1 PF01416.20 CEG47782.1 - 0.12 12.8 0.2 3.5 8.2 0.1 2.5 2 0 0 2 2 2 0 tRNA pseudouridine synthase TPR_1 PF00515.28 CEG47783.1 - 2.5e-07 30.2 0.1 3.5e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG47783.1 - 1.8e-05 24.5 0.1 7.6e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG47783.1 - 0.0023 18.0 0.3 0.0052 16.9 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG47783.1 - 0.0041 17.1 0.3 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG47783.1 - 0.011 16.4 0.0 0.49 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEG47783.1 - 0.013 15.2 0.8 0.017 14.8 0.1 1.6 2 0 0 2 2 2 0 TPR repeat TUDOR_5 PF18359.1 CEG47783.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Sel1 PF08238.12 CEG47783.1 - 0.026 15.2 0.1 0.076 13.7 0.1 1.8 1 0 0 1 1 1 0 Sel1 repeat TPR_12 PF13424.6 CEG47783.1 - 0.029 14.7 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 CEG47783.1 - 0.054 13.0 0.0 0.2 11.1 0.0 1.8 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Meiosis_expr PF15163.6 CEG47784.1 - 1.5e-28 99.2 5.1 2.2e-28 98.7 5.1 1.2 1 0 0 1 1 1 1 Meiosis-expressed SAC3_GANP PF03399.16 CEG47785.1 - 1.3e-60 205.3 4.2 1.5e-60 205.1 4.2 1.0 1 0 0 1 1 1 1 SAC3/GANP family Rio2_N PF09202.11 CEG47785.1 - 0.057 13.6 0.1 0.66 10.2 0.0 2.6 1 1 0 2 2 2 0 Rio2, N-terminal DUF3546 PF12066.8 CEG47786.1 - 8.3e-17 61.4 3.6 2e-16 60.1 3.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 CEG47786.1 - 3.4e-12 47.1 0.2 7.4e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 CEG47786.1 - 0.00097 18.9 0.0 0.0029 17.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 CEG47786.1 - 0.32 11.6 3.6 1.3 9.6 3.6 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type MARVEL PF01284.23 CEG47786.1 - 4.2 7.4 10.6 19 5.2 10.6 1.9 1 1 0 1 1 1 0 Membrane-associating domain RIIa PF02197.17 CEG47787.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 CEG47787.1 - 0.029 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) EF-hand_1 PF00036.32 CEG47787.1 - 0.05 13.2 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 EF hand ABC2_membrane PF01061.24 CEG47790.1 - 3.7e-28 98.4 22.8 3.7e-28 98.4 22.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CEG47790.1 - 7.1e-21 75.2 0.0 2.3e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CEG47790.1 - 2.4e-09 37.4 0.0 8e-05 22.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEG47790.1 - 6.6e-05 23.3 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CEG47790.1 - 0.0018 18.8 0.6 0.0049 17.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEG47790.1 - 0.0019 17.9 0.2 0.0052 16.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CEG47790.1 - 0.0088 15.6 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CEG47790.1 - 0.012 14.7 24.3 0.02 14.0 24.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_22 PF13401.6 CEG47790.1 - 0.013 15.8 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEG47790.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 CEG47790.1 - 0.044 13.2 0.0 9.5 5.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CEG47790.1 - 0.066 13.5 0.1 0.15 12.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 CEG47790.1 - 0.12 12.3 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CEG47790.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 CEG47790.1 - 0.21 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CEG47790.1 - 0.24 11.1 0.1 0.46 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF4636 PF15468.6 CEG47791.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Hyr1 PF15789.5 CEG47792.1 - 0.085 12.4 1.3 0.14 11.8 1.3 1.3 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 SecM PF06558.12 CEG47794.1 - 0.71 10.0 4.9 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) YabA PF06156.13 CEG47794.1 - 7.3 7.3 19.7 0.29 11.8 3.6 3.5 1 1 2 3 3 3 0 Initiation control protein YabA ALMT PF11744.8 CEG47794.1 - 9.5 4.9 10.9 17 4.1 10.9 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Myb_DNA-binding PF00249.31 CEG47795.1 - 3.8e-13 49.4 0.5 6.2e-13 48.7 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG47795.1 - 0.00018 21.4 0.6 0.00054 19.8 0.6 1.8 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CEG47795.1 - 0.005 17.1 0.3 0.009 16.2 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dimer_Tnp_hAT PF05699.14 CEG47800.1 - 1.1e-10 41.2 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mpv17_PMP22 PF04117.12 CEG47802.1 - 3.6e-19 68.7 1.4 6.9e-19 67.8 1.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 CEG47803.1 - 1.7e-17 63.4 0.1 4.2e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MIF4G PF02854.19 CEG47804.1 - 5.1e-41 140.7 0.1 8.4e-19 68.0 0.3 3.9 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CEG47804.1 - 5.2e-19 69.3 1.6 5.2e-19 69.3 1.6 3.3 3 1 1 4 4 4 1 Up-frameshift suppressor 2 YL1 PF05764.13 CEG47804.1 - 0.0022 18.2 16.5 0.0022 18.2 16.5 2.6 2 0 0 2 2 2 1 YL1 nuclear protein TF_AP-2 PF03299.14 CEG47804.1 - 0.15 12.1 2.1 0.4 10.6 0.7 2.3 2 0 0 2 2 2 0 Transcription factor AP-2 HSL_N PF06350.12 CEG47804.1 - 0.15 11.0 0.8 0.5 9.3 0.2 2.0 2 0 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus SDA1 PF05285.12 CEG47804.1 - 0.18 11.2 35.2 0.0095 15.4 22.0 2.5 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 CEG47804.1 - 0.75 9.1 36.5 1.8 7.8 22.7 2.7 2 0 0 2 2 2 0 BUD22 RVT_2 PF07727.14 CEG47805.1 - 4.7e-10 39.5 0.0 6.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Solute_trans_a PF03619.16 CEG47806.1 - 3e-68 230.2 19.9 9.2e-42 143.4 3.5 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Abhydrolase_9_N PF15420.6 CEG47806.1 - 0.39 10.7 2.0 0.67 9.9 0.8 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus HTH_Tnp_Tc3_2 PF01498.18 CEG47809.1 - 0.0088 16.3 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Transposase Glyco_hydro_28 PF00295.17 CEG47810.1 - 3.3e-68 230.1 13.9 4.3e-68 229.8 13.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CEG47810.1 - 3.4e-07 30.3 16.4 7.4e-07 29.1 13.9 2.5 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 CEG47810.1 - 0.00038 19.8 10.6 0.0004 19.7 9.4 1.7 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) DUF4957 PF16318.5 CEG47810.1 - 0.092 12.7 4.8 0.33 10.9 4.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) NUDIX PF00293.28 CEG47811.1 - 4e-14 52.8 0.3 5.2e-14 52.4 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1e PF01406.19 CEG47812.1 - 7.9e-118 393.2 0.0 1.1e-117 392.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 CEG47812.1 - 3.1e-07 30.8 0.0 1.3e-06 28.8 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 CEG47812.1 - 2.8e-05 23.1 0.1 7.6e-05 21.6 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CEG47812.1 - 0.0027 16.6 0.0 0.0092 14.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain SRA1 PF07304.11 CEG47812.1 - 0.0052 16.6 0.8 0.025 14.4 0.2 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) DUF5399 PF17377.2 CEG47812.1 - 0.029 14.2 1.0 0.23 11.3 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5399) tRNA-synt_1 PF00133.22 CEG47812.1 - 0.089 11.0 0.0 0.15 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) 6PF2K PF01591.18 CEG47813.1 - 4.6e-69 232.1 0.2 7.2e-69 231.5 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEG47813.1 - 3.4e-29 101.9 0.0 1.9e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEG47813.1 - 1e-07 32.2 0.2 3.8e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain DUF2415 PF10313.9 CEG47813.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) ATPase PF06745.13 CEG47813.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC IQ PF00612.27 CEG47814.1 - 0.41 10.6 9.9 0.054 13.3 5.6 1.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ribosomal_L6e PF01159.19 CEG47815.1 - 6.1e-29 100.8 0.5 2.4e-28 98.9 0.5 1.9 1 1 0 1 1 1 1 Ribosomal protein L6e CDC45 PF02724.14 CEG47817.1 - 0.0019 16.6 5.5 0.0023 16.3 5.5 1.0 1 0 0 1 1 1 1 CDC45-like protein AAA_11 PF13086.6 CEG47817.1 - 0.013 15.3 8.6 0.015 15.1 8.6 1.1 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.6 CEG47817.1 - 0.027 14.1 7.3 0.042 13.4 7.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3106 PF11304.8 CEG47817.1 - 0.028 14.9 0.5 0.028 14.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) CENP-K PF11802.8 CEG47817.1 - 0.063 12.8 8.7 0.075 12.6 8.7 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Glu-tRNAGln PF02686.15 CEG47817.1 - 0.1 12.9 2.5 0.24 11.7 0.0 2.5 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF445 PF04286.12 CEG47817.1 - 0.12 12.2 6.0 0.14 12.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RR_TM4-6 PF06459.12 CEG47817.1 - 0.12 12.2 7.4 0.15 11.9 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 CEG47817.1 - 0.12 11.2 4.1 0.14 11.0 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_III_AB PF09548.10 CEG47817.1 - 0.23 11.6 4.4 0.45 10.6 4.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SseC PF04888.12 CEG47817.1 - 0.35 10.4 4.1 0.43 10.1 1.9 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Zip PF02535.22 CEG47817.1 - 0.47 9.6 2.7 0.63 9.2 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter WDCP PF15390.6 CEG47817.1 - 0.47 8.8 6.1 0.56 8.5 6.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Efg1 PF10153.9 CEG47817.1 - 0.53 10.7 14.6 1.3 9.5 14.6 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Tfb4 PF03850.14 CEG47817.1 - 0.63 9.5 3.7 0.65 9.4 2.6 1.4 1 1 0 1 1 1 0 Transcription factor Tfb4 EMC3_TMCO1 PF01956.16 CEG47817.1 - 0.72 9.6 2.0 1.1 8.9 2.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like BRF1 PF07741.13 CEG47817.1 - 0.9 9.9 12.5 0.55 10.6 9.9 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Presenilin PF01080.17 CEG47817.1 - 0.92 8.2 3.7 1 8.1 3.7 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 CEG47817.1 - 1.5 7.2 16.1 1.8 6.9 16.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 CEG47817.1 - 1.5 8.0 5.7 2.4 7.3 5.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Goodbye PF17109.5 CEG47817.1 - 2.1 8.8 6.5 10 6.6 5.3 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain RP-C_C PF11800.8 CEG47817.1 - 2.2 8.4 8.9 1.8 8.6 7.8 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region NACHT_N PF17100.5 CEG47817.1 - 2.3 8.0 9.2 1.4 8.8 6.5 1.8 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase V-SNARE PF05008.15 CEG47818.1 - 1.6e-12 47.6 3.5 3.6e-12 46.5 3.5 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CEG47818.1 - 8e-07 28.9 2.0 0.00026 20.9 0.0 3.0 2 2 1 3 3 3 2 Sec20 V-SNARE_C PF12352.8 CEG47818.1 - 1.5e-05 25.2 1.0 4.9e-05 23.5 0.2 2.3 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus ZnuA PF01297.17 CEG47818.1 - 0.013 14.9 1.0 0.013 14.9 1.0 1.5 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DNA_pol_B PF00136.21 CEG47818.1 - 0.022 13.5 0.9 0.026 13.2 0.9 1.2 1 0 0 1 1 1 0 DNA polymerase family B PEPcase PF00311.17 CEG47818.1 - 0.081 11.0 3.1 0.073 11.1 0.6 1.8 1 1 0 2 2 2 0 Phosphoenolpyruvate carboxylase DUF1664 PF07889.12 CEG47818.1 - 0.19 11.8 7.6 5.4 7.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phe_tRNA-synt_N PF02912.18 CEG47818.1 - 2.4 8.2 8.6 1.9 8.5 1.7 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Spc7 PF08317.11 CEG47818.1 - 4 6.2 10.5 1.6 7.5 8.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein IMD PF08397.11 CEG47818.1 - 5.3 6.4 10.3 3.2 7.1 2.3 2.4 1 1 1 2 2 2 0 IRSp53/MIM homology domain CENP-Q PF13094.6 CEG47820.1 - 0.17 12.1 18.4 3.6 7.8 18.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FYVE PF01363.21 CEG47821.1 - 3.8e-06 26.9 7.5 3.8e-06 26.9 7.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 CEG47821.1 - 3.3 8.0 6.8 1.6 9.0 2.4 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 CEG47821.1 - 3.6 7.8 9.9 1 9.6 1.1 2.7 2 0 0 2 2 2 0 B-box zinc finger DUF4558 PF15104.6 CEG47822.1 - 5.7e-21 74.4 4.7 6.9e-21 74.1 4.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) Ldh_1_C PF02866.18 CEG47823.1 - 2.5e-50 170.7 0.0 6.3e-50 169.4 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CEG47823.1 - 3.4e-44 150.4 0.5 5e-44 149.8 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CEG47823.1 - 3.9e-05 22.8 0.0 0.00051 19.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CEG47823.1 - 0.024 14.8 0.2 0.059 13.5 0.2 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CEG47823.1 - 0.13 12.7 0.6 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CEG47823.1 - 0.19 11.3 1.3 2.9 7.4 0.7 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase SURF2 PF05477.11 CEG47824.1 - 5.1e-09 36.2 10.1 6.1e-09 35.9 10.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Tub_N PF16322.5 CEG47824.1 - 0.86 10.0 9.7 1.1 9.6 9.7 1.2 1 0 0 1 1 1 0 Tubby N-terminal CDC45 PF02724.14 CEG47824.1 - 2.3 6.4 12.2 2.3 6.4 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein BATS PF06968.13 CEG47825.1 - 2.7e-18 65.9 0.3 8.9e-18 64.2 0.3 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CEG47825.1 - 6.1e-15 56.0 0.8 9.2e-15 55.4 0.8 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SAMP PF05924.11 CEG47826.1 - 2.5 7.5 9.7 24 4.4 0.1 4.7 4 0 0 4 4 4 0 SAMP Motif DUF370 PF04025.12 CEG47827.1 - 0.083 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF370) GST_N_2 PF13409.6 CEG47827.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RIO1 PF01163.22 CEG47828.1 - 1.2e-48 165.2 0.0 1.9e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CEG47828.1 - 2.2e-35 120.7 0.4 5.6e-35 119.4 0.3 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CEG47828.1 - 2.3e-06 27.7 0.1 0.0012 18.9 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEG47828.1 - 4.3e-05 23.0 0.1 0.0058 16.0 0.1 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CEG47828.1 - 0.0039 16.6 0.4 0.014 14.8 0.4 1.8 1 1 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 CEG47829.1 - 4.8e-30 103.5 8.2 7.9e-10 39.1 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG47829.1 - 1.5e-29 102.4 6.4 2.3e-15 56.9 1.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG47829.1 - 1.1e-20 73.5 0.6 8.1e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG47829.1 - 6.5e-20 70.6 2.2 3.7e-05 24.0 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CEG47829.1 - 1.3e-19 68.2 0.0 0.00019 21.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat DEAD PF00270.29 CEG47830.1 - 2e-28 99.3 0.0 9.2e-26 90.7 0.0 2.9 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG47830.1 - 4e-26 91.5 0.0 3.6e-25 88.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEG47830.1 - 1.3e-21 76.5 0.0 2.7e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Aminotran_1_2 PF00155.21 CEG47831.1 - 3.5e-55 187.7 0.0 4e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEG47831.1 - 0.00013 20.6 0.0 0.0002 20.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEG47831.1 - 0.0065 15.5 0.0 0.0094 14.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V HisKA_2 PF07568.12 CEG47833.1 - 0.25 11.4 2.2 0.88 9.7 1.0 2.6 2 0 0 2 2 2 0 Histidine kinase KLRAQ PF10205.9 CEG47833.1 - 1 9.7 0.0 1 9.7 0.0 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein RPW8 PF05659.11 CEG47833.1 - 1.1 9.0 4.3 15 5.2 0.1 3.2 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RasGAP_C PF03836.15 CEG47833.1 - 1.2 9.3 6.8 0.15 12.2 0.9 2.4 3 0 0 3 3 3 0 RasGAP C-terminus Seryl_tRNA_N PF02403.22 CEG47833.1 - 3 8.1 7.7 2 8.7 0.4 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 CEG47833.1 - 4.8 7.7 8.3 14 6.2 0.2 3.0 2 0 0 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 CEG47833.1 - 6.9 7.1 6.1 1.6 9.1 0.3 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 CEG47835.1 - 0.01 15.0 9.0 0.01 15.0 9.0 3.1 1 1 2 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 CEG47835.1 - 5.8 7.1 23.0 1.7 8.8 5.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 CEG47835.1 - 6.5 6.9 52.4 0.26 11.5 18.9 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) G-gamma PF00631.22 CEG47836.1 - 2.3e-10 40.3 0.0 2.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 GGL domain Paralemmin PF03285.15 CEG47836.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Paralemmin CAP PF00188.26 CEG47836.1 - 0.02 15.7 0.0 0.023 15.5 0.0 1.1 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Fzo_mitofusin PF04799.13 CEG47836.1 - 0.058 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region Exonuc_VII_S PF02609.16 CEG47836.1 - 0.08 13.0 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Exonuclease VII small subunit RVT_2 PF07727.14 CEG47838.1 - 2.3e-26 92.9 0.1 3.2e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM240 PF15207.6 CEG47838.1 - 0.12 12.1 0.6 0.2 11.3 0.6 1.3 1 0 0 1 1 1 0 TMEM240 family SET PF00856.28 CEG47840.1 - 1.5e-12 48.2 0.0 1.5e-12 48.2 0.0 3.8 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CEG47840.1 - 2.8e-09 37.3 16.1 2.8e-09 37.3 16.1 3.1 3 0 0 3 3 3 1 CXC domain FAD_binding_4 PF01565.23 CEG47841.1 - 7.5e-18 64.6 0.4 1.1e-17 64.1 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CEG47841.1 - 1.2e-08 34.9 0.1 2.9e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like APC1_C PF18122.1 CEG47842.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain TTL PF03133.15 CEG47845.1 - 3.6e-28 98.5 0.2 1.4e-27 96.6 0.2 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_2 PF07974.13 CEG47845.1 - 0.00026 21.3 5.9 0.00057 20.2 5.9 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 CEG47845.1 - 0.00074 19.5 3.1 0.0017 18.4 3.1 1.6 1 0 0 1 1 1 1 Tenascin EGF domain ArfGap PF01412.18 CEG47847.1 - 3.1e-32 111.1 0.1 7.9e-32 109.8 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 CEG47847.1 - 0.27 11.2 1.9 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Transket_pyr PF02779.24 CEG47848.1 - 8.2e-46 155.9 0.0 1.6e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEG47848.1 - 2e-42 144.0 0.0 5.4e-42 142.6 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CEG47848.1 - 3.5e-05 24.0 0.1 0.00011 22.5 0.0 1.8 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II ADH_N PF08240.12 CEG47849.1 - 1.5e-18 66.7 3.8 1.5e-18 66.7 3.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEG47849.1 - 3.3e-07 30.3 0.0 0.00023 21.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase PP2C PF00481.21 CEG47851.1 - 8.8e-41 140.2 0.0 1.2e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEG47851.1 - 0.0015 18.2 0.0 0.0034 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CEG47851.1 - 0.044 13.7 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) BT1 PF03092.16 CEG47852.1 - 3.5e-87 292.8 18.3 7.3e-51 173.0 8.1 3.0 1 1 2 3 3 3 3 BT1 family UPRTase PF14681.6 CEG47858.1 - 1.2e-32 113.1 0.0 3.3e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase ABC_tran PF00005.27 CEG47860.1 - 6.4e-15 55.9 0.0 9.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CEG47860.1 - 4.8e-05 23.0 0.1 0.00035 20.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CEG47860.1 - 8.2e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEG47860.1 - 0.00035 20.4 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CEG47860.1 - 0.00055 20.4 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEG47860.1 - 0.00061 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 CEG47860.1 - 0.003 17.8 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CEG47860.1 - 0.0081 16.7 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CEG47860.1 - 0.0091 15.6 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CEG47860.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CEG47860.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 CEG47860.1 - 0.023 14.8 7.0 0.023 14.8 7.0 2.9 3 0 0 3 3 1 0 Laminin EGF domain AAA_21 PF13304.6 CEG47860.1 - 0.026 14.4 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CEG47860.1 - 0.032 14.8 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEG47860.1 - 0.039 13.7 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG47860.1 - 0.044 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CEG47860.1 - 0.055 13.6 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CEG47860.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CEG47860.1 - 0.14 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CEG47860.1 - 0.15 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TsaE PF02367.17 CEG47860.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CEG47860.1 - 0.18 11.9 0.2 0.44 10.6 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CEG47860.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CEG47860.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CEG47860.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 CEG47861.1 - 2.4e-32 112.1 22.9 2.4e-32 112.1 22.9 1.4 2 0 0 2 2 2 1 ABC-2 type transporter Mannosyl_trans4 PF15971.5 CEG47861.1 - 0.021 14.7 1.9 0.021 14.7 1.9 1.7 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase BRCT_2 PF16589.5 CEG47862.1 - 0.021 15.2 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF1962 PF09227.10 CEG47862.1 - 0.18 12.2 0.6 0.41 11.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1962) DUF4455 PF14643.6 CEG47864.1 - 3.7e-47 161.1 30.0 4e-34 118.1 3.5 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 CEG47864.1 - 4.3e-26 91.9 15.3 4.3e-26 91.9 15.3 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4456) Synaptobrevin PF00957.21 CEG47864.1 - 0.054 13.3 0.3 0.96 9.3 1.0 2.8 2 0 0 2 2 2 0 Synaptobrevin RHH_4 PF13467.6 CEG47864.1 - 0.16 11.8 1.0 0.55 10.2 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain RNA_pol_Rbc25 PF08292.12 CEG47865.1 - 4.6e-34 117.4 0.0 7.9e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CEG47865.1 - 2.1e-14 53.6 0.2 5.4e-14 52.3 0.2 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CEG47865.1 - 0.0026 18.1 0.2 0.0076 16.6 0.0 2.0 2 1 0 2 2 2 1 S1 RNA binding domain Cation_efflux PF01545.21 CEG47866.1 - 1.3e-29 103.4 9.9 1.6e-29 103.1 9.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CEG47866.1 - 8.5e-08 32.2 1.0 1.6e-07 31.3 1.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2583 PF10762.9 CEG47866.1 - 3.9 8.0 4.8 0.98 9.9 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Aldose_epim PF01263.20 CEG47871.1 - 1.4e-36 126.4 0.0 1.5e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Peptidase_C47 PF05543.13 CEG47871.1 - 0.032 13.8 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 FGF PF00167.18 CEG47871.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 1 0 1 1 1 0 Fibroblast growth factor Acid_PPase PF12689.7 CEG47871.1 - 0.26 11.1 1.4 0.32 10.8 0.2 1.7 2 0 0 2 2 2 0 Acid Phosphatase TPH PF13868.6 CEG47872.1 - 3.9e-44 150.6 128.0 3.9e-44 150.6 128.0 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain SprT-like PF10263.9 CEG47873.1 - 2.1e-29 101.7 0.1 4.1e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 SprT-like family PIN_6 PF17146.4 CEG47875.1 - 3.2e-28 98.1 0.0 5.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CEG47875.1 - 6e-27 93.6 0.6 1.2e-26 92.7 0.6 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-CCCH PF00642.24 CEG47875.1 - 2e-10 40.3 10.1 9.9e-06 25.3 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEG47875.1 - 4.5e-07 29.5 16.1 0.00011 21.9 1.7 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG47875.1 - 1.3e-05 25.4 12.2 0.0044 17.4 1.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CEG47875.1 - 4.6e-05 23.3 12.8 0.011 15.7 1.9 3.0 2 1 0 2 2 2 2 Zinc finger domain oligo_HPY PF08352.12 CEG47875.1 - 0.028 14.9 1.2 8.5 7.0 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_3 PF15663.5 CEG47875.1 - 0.05 13.8 2.0 0.42 10.8 2.0 2.2 1 1 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 CEG47875.1 - 0.076 13.7 9.7 0.11 13.2 0.8 2.9 2 1 1 3 3 3 0 Torus domain UBZ_FAAP20 PF15750.5 CEG47875.1 - 0.13 12.3 0.3 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger ATP-synt_ab PF00006.25 CEG47876.1 - 6.1e-106 352.8 0.0 9.9e-106 352.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CEG47876.1 - 7.4e-38 129.1 0.0 1.3e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CEG47876.1 - 1.2e-14 54.5 1.0 2.4e-14 53.6 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 CEG47876.1 - 0.04 14.5 0.1 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Metallophos PF00149.28 CEG47877.1 - 1.6e-27 97.3 0.1 3.2e-27 96.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 CEG47877.1 - 1.1e-09 37.1 3.3 4.1e-05 22.8 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CEG47877.1 - 1.9e-09 36.7 2.9 8.3e-05 22.2 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CEG47877.1 - 4.9e-08 33.3 0.4 4.9e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair PPP5 PF08321.12 CEG47877.1 - 7.6e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_5 PF13202.6 CEG47877.1 - 3.4e-06 26.3 1.9 5.9e-05 22.4 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CEG47877.1 - 0.0007 19.4 1.7 0.019 14.8 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair DUF2613 PF11021.8 CEG47881.1 - 0.0063 16.6 7.0 0.59 10.3 1.4 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2613) SDA1 PF05285.12 CEG47881.1 - 0.011 15.2 17.7 0.013 15.0 17.7 1.1 1 0 0 1 1 1 0 SDA1 MPM1 PF17234.2 CEG47881.1 - 0.019 15.2 7.3 0.032 14.5 7.3 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SID-1_RNA_chan PF13965.6 CEG47881.1 - 0.09 11.2 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sporozoite_P67 PF05642.11 CEG47881.1 - 0.13 10.4 9.3 0.15 10.1 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 CEG47881.1 - 0.26 11.7 4.5 0.42 11.0 4.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CEG47881.1 - 0.36 9.1 13.4 0.45 8.7 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CEG47881.1 - 1.5 7.5 6.6 2.3 6.9 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Serinc PF03348.15 CEG47881.1 - 2.2 7.1 5.1 0.17 10.8 0.3 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) CPSF100_C PF13299.6 CEG47881.1 - 3.6 7.8 7.5 6.4 6.9 7.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 CEG47881.1 - 4.3 6.0 10.6 5.4 5.7 10.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 CEG47881.1 - 7.6 5.7 8.1 1.3 8.2 4.7 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Hid1 PF12722.7 CEG47881.1 - 9 4.3 7.7 11 4.0 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAD_binding_7 PF03441.14 CEG47882.1 - 5.1e-76 254.6 0.8 7.5e-76 254.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEG47882.1 - 5.4e-37 127.3 0.0 9.4e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cadherin PF00028.17 CEG47882.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Cadherin domain MFS_1_like PF12832.7 CEG47883.1 - 1.1e-60 205.5 22.0 2.5e-60 204.4 22.0 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CEG47883.1 - 4.6e-20 71.8 50.6 8.8e-16 57.8 25.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CEG47883.1 - 1.1e-13 51.0 18.6 1.6e-13 50.4 18.6 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 CEG47883.1 - 2.8e-10 39.6 18.7 5.3e-10 38.6 18.7 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter S-methyl_trans PF02574.16 CEG47884.1 - 3.5e-62 210.7 0.0 4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase APOBEC4_like PF18774.1 CEG47886.1 - 0.042 13.8 0.2 0.048 13.6 0.2 1.1 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase FAD_binding_7 PF03441.14 CEG47887.1 - 7.7e-68 228.0 1.1 1.4e-67 227.1 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CEG47887.1 - 1.3e-31 109.8 0.0 2.3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF4733 PF15878.5 CEG47887.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) RT_RNaseH_2 PF17919.1 CEG47888.1 - 4.7e-19 68.3 0.0 1.8e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEG47888.1 - 2.8e-08 34.0 0.0 1.1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase FbpA PF05833.11 CEG47888.1 - 0.0027 16.6 7.4 0.0035 16.2 7.4 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SLC12 PF03522.15 CEG47888.1 - 0.064 12.3 4.5 0.089 11.8 4.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Leo1 PF04004.13 CEG47889.1 - 6.6e-37 126.9 0.3 1.3e-36 125.9 0.3 1.5 1 0 0 1 1 1 1 Leo1-like protein FAM219A PF15260.6 CEG47889.1 - 0.97 9.8 7.3 0.059 13.7 0.8 2.2 2 1 1 3 3 3 0 Protein family FAM219A Rad51 PF08423.11 CEG47891.1 - 1.3e-33 116.3 0.1 2.8e-32 112.0 0.1 2.0 1 1 0 1 1 1 1 Rad51 EF-hand_5 PF13202.6 CEG47894.1 - 0.00012 21.4 0.0 0.00042 19.7 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CEG47894.1 - 0.00091 18.6 0.0 0.0038 16.7 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEG47894.1 - 0.0032 17.3 0.6 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CEG47894.1 - 0.038 14.4 0.1 0.33 11.4 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 CEG47894.1 - 0.039 13.8 0.1 14 5.6 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain pair L31 PF09784.9 CEG47896.1 - 0.065 13.7 1.0 0.077 13.4 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 LRR_4 PF12799.7 CEG47897.1 - 6.3e-11 42.3 13.2 0.00036 20.8 0.1 4.1 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG47897.1 - 1.1e-09 37.9 12.6 5.2e-06 26.1 4.7 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CEG47897.1 - 1e-06 28.4 1.8 0.017 14.7 0.1 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CEG47897.1 - 0.063 13.4 6.4 1.6 9.0 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat FlaC_arch PF05377.11 CEG47897.1 - 2.9 8.3 5.8 1.2 9.6 0.7 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 CEG47897.1 - 3.1 7.7 9.9 1.2 9.0 2.1 3.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BssS PF13991.6 CEG47899.1 - 0.14 12.2 0.0 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 BssS protein family MAP7 PF05672.11 CEG47899.1 - 0.22 11.2 9.3 5.2 6.7 0.0 3.1 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family Tnp_DNA_bind PF14706.6 CEG47900.1 - 0.022 14.6 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Transposase DNA-binding ubiquitin PF00240.23 CEG47902.1 - 2e-18 65.9 0.0 4.6e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG47902.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CEG47902.1 - 0.00019 21.5 0.0 0.00055 20.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CEG47902.1 - 0.063 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CEG47902.1 - 0.067 13.2 0.1 1.2 9.3 0.1 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 CEG47902.1 - 0.13 12.9 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RIBIOP_C PF04950.12 CEG47903.1 - 7.7e-98 327.5 0.0 1.6e-97 326.4 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CEG47903.1 - 2e-20 72.6 0.0 7.7e-20 70.8 0.0 1.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain TFIIA PF03153.13 CEG47903.1 - 0.019 15.0 8.0 0.036 14.1 8.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 CEG47904.1 - 1.2e-38 132.6 0.0 4.1e-38 130.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG47904.1 - 8e-21 74.5 0.2 4.2e-20 72.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG47904.1 - 4.9e-11 42.9 0.0 9.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CEG47904.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HTH_AraC PF00165.23 CEG47904.1 - 0.069 13.3 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family AAA_22 PF13401.6 CEG47904.1 - 0.075 13.3 0.0 23 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain IPPT PF01715.17 CEG47905.1 - 9.8e-68 228.4 0.0 1.5e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 CEG47905.1 - 2.3e-05 24.6 2.7 0.00037 20.7 0.3 3.4 3 1 0 3 3 3 1 AAA domain IPT PF01745.16 CEG47905.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase DUF3449 PF11931.8 CEG47905.1 - 0.00071 19.4 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) AAA_18 PF13238.6 CEG47905.1 - 0.0011 19.5 0.1 0.18 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain zf-C2H2_2 PF12756.7 CEG47905.1 - 0.076 13.4 2.6 0.35 11.2 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Cytidylate_kin PF02224.18 CEG47905.1 - 0.1 12.3 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 CEG47905.1 - 0.36 11.1 1.9 1.1 9.5 0.2 2.6 3 1 0 3 3 3 0 AAA domain Ribosomal_L7Ae PF01248.26 CEG47906.1 - 4.7e-09 35.9 0.0 9.4e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_4 PF13439.6 CEG47906.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RNase_P_pop3 PF08228.11 CEG47906.1 - 0.02 14.9 0.1 0.046 13.8 0.1 1.5 1 1 1 2 2 2 0 RNase P subunit Pop3 Glyco_trans_4_4 PF13579.6 CEG47906.1 - 0.053 13.9 0.2 0.084 13.3 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ubiquitin PF00240.23 CEG47907.1 - 1.4e-17 63.2 0.0 2.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG47907.1 - 0.00023 20.9 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEG47907.1 - 0.00097 19.6 0.0 0.0026 18.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEG47907.1 - 0.0031 17.6 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEG47907.1 - 0.048 14.2 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain NSP10 PF09401.10 CEG47908.1 - 0.018 15.1 0.2 0.019 15.0 0.2 1.1 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Surp PF01805.20 CEG47910.1 - 4.9e-36 122.5 0.4 1.4e-16 60.2 0.0 2.7 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 CEG47910.1 - 9.6e-24 84.5 9.0 1.6e-15 57.6 3.3 3.9 3 1 1 4 4 4 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 CEG47910.1 - 2.8e-07 30.2 0.1 7.2e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Spt20 PF12090.8 CEG47910.1 - 2.4 7.7 15.5 4.1 6.9 8.7 2.3 2 0 0 2 2 2 0 Spt20 family DDHD PF02862.17 CEG47910.1 - 4.6 7.3 9.6 0.063 13.4 1.0 2.1 2 1 0 2 2 2 0 DDHD domain Ras PF00071.22 CEG47911.1 - 6.7e-48 162.3 0.0 9.1e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG47911.1 - 1.1e-29 103.1 0.0 2.8e-29 101.8 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG47911.1 - 1.5e-09 37.5 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG47911.1 - 7.4e-05 22.8 0.0 0.00022 21.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CEG47911.1 - 0.00021 21.7 0.2 0.0021 18.4 0.1 2.3 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 CEG47911.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEG47911.1 - 0.013 15.4 0.0 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 CEG47911.1 - 0.032 14.2 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEG47911.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 CEG47911.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.6 CEG47911.1 - 0.07 13.5 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CEG47911.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin ArgoMid PF16487.5 CEG47911.1 - 0.11 12.7 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 CEG47911.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEG47911.1 - 0.14 12.3 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Nop10p PF04135.12 CEG47912.1 - 2e-22 78.9 0.2 2.8e-22 78.5 0.2 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family SNF2_N PF00176.23 CEG47913.1 - 4.2e-45 154.0 0.0 6.9e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG47913.1 - 2.8e-22 79.2 0.1 1.5e-20 73.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEG47913.1 - 1.5e-07 30.9 0.2 3.6e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 CEG47913.1 - 0.00013 21.3 0.3 0.00033 20.0 0.1 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 CEG47914.1 - 2.7e-19 69.1 14.9 4.1e-05 24.3 0.4 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG47914.1 - 1.6e-12 47.6 3.2 0.08 13.2 0.0 7.4 3 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.13 CEG47914.1 - 0.0051 15.6 0.0 0.041 12.6 0.0 2.2 2 0 0 2 2 2 1 Vps16, N-terminal region IKI3 PF04762.12 CEG47914.1 - 0.034 12.2 2.3 6.2 4.7 0.0 3.7 2 1 1 3 3 3 0 IKI3 family Coatomer_WDAD PF04053.14 CEG47914.1 - 0.14 11.1 2.8 6 5.8 0.2 3.8 3 2 1 4 4 4 0 Coatomer WD associated region YmzC PF14157.6 CEG47914.1 - 0.16 12.1 0.1 5.5 7.2 0.0 2.9 3 0 0 3 3 3 0 YmzC-like protein Citrate_bind PF16114.5 CEG47917.1 - 2.5e-89 297.4 0.0 4.9e-89 296.5 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CEG47917.1 - 2.6e-23 82.7 0.0 7.6e-21 74.6 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CEG47917.1 - 1.2e-13 51.2 0.1 2.5e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CEG47917.1 - 1.1e-05 26.1 0.0 3.6e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 CEG47917.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SAM_1 PF00536.30 CEG47918.1 - 6e-07 29.8 0.1 1.3e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG47918.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TetR_C_35 PF18556.1 CEG47918.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain PSI_PsaH PF03244.14 CEG47918.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI HhH-GPD PF00730.25 CEG47918.1 - 0.12 12.9 0.1 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein MCM2_N PF12619.8 CEG47918.1 - 0.68 10.2 8.5 0.33 11.2 0.8 2.7 3 0 0 3 3 3 0 Mini-chromosome maintenance protein 2 CDT1 PF08839.11 CEG47919.1 - 9.7e-19 68.3 0.3 2.1e-18 67.2 0.2 1.6 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 CEG47919.1 - 9.7e-09 35.6 5.4 2.9e-08 34.0 2.2 2.9 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain TDP43_N PF18694.1 CEG47919.1 - 0.12 12.2 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain Voltage_CLC PF00654.20 CEG47923.1 - 5.8e-61 206.7 34.5 9.6e-61 206.0 34.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CEG47923.1 - 0.0075 16.7 0.4 0.02 15.3 0.1 2.0 2 0 0 2 2 2 1 CBS domain Caveolin PF01146.17 CEG47923.1 - 1.2 9.1 8.1 0.28 11.1 1.6 2.7 2 0 0 2 2 2 0 Caveolin NPP1 PF05630.11 CEG47924.1 - 1.1e-44 152.9 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Peptidase_M1 PF01433.20 CEG47925.1 - 8e-23 81.2 1.2 8.2e-23 81.1 1.2 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain RIG-I_C-RD PF11648.8 CEG47926.1 - 0.0006 20.0 0.6 0.0014 18.8 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of RIG-I Peptidase_M1 PF01433.20 CEG47927.1 - 3.8e-14 52.8 0.5 1.3e-05 24.9 0.0 2.7 2 1 1 3 3 3 2 Peptidase family M1 domain ABC2_membrane PF01061.24 CEG47929.1 - 1.3e-66 224.0 55.2 1.1e-38 132.8 19.6 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG47929.1 - 5.4e-34 117.6 0.0 1.7e-16 60.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 CEG47929.1 - 2.2e-06 27.3 0.6 0.013 15.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG47929.1 - 4.7e-06 26.6 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 CEG47929.1 - 1.2e-05 24.7 12.8 1.2e-05 24.7 12.8 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CEG47929.1 - 3.5e-05 23.8 0.3 2.1 8.1 0.1 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CEG47929.1 - 5.4e-05 23.5 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEG47929.1 - 0.0001 22.0 0.1 0.43 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CEG47929.1 - 0.00021 21.4 0.4 1.5 8.9 0.1 3.3 4 0 0 4 4 4 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CEG47929.1 - 0.00023 21.7 1.8 0.15 12.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEG47929.1 - 0.00059 19.6 1.9 0.54 10.0 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG47929.1 - 0.0011 19.4 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CEG47929.1 - 0.0012 19.4 0.1 2.5 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 CEG47929.1 - 0.0022 17.7 0.8 0.011 15.5 0.8 2.2 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_33 PF13671.6 CEG47929.1 - 0.0073 16.5 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEG47929.1 - 0.011 15.9 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG47929.1 - 0.016 15.6 0.7 9.4 6.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEG47929.1 - 0.016 15.6 0.4 14 6.1 0.0 3.5 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 CEG47929.1 - 0.019 14.9 1.3 0.73 9.8 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CEG47929.1 - 0.028 13.7 1.3 4 6.7 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 CEG47929.1 - 0.036 14.4 0.5 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEG47929.1 - 0.051 13.5 2.8 3.8 7.4 0.7 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CEG47929.1 - 0.051 13.1 1.4 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEG47929.1 - 0.062 13.4 3.3 2.5 8.2 0.7 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SMC_N PF02463.19 CEG47929.1 - 0.071 12.5 0.1 6.3 6.2 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Ploopntkinase3 PF18751.1 CEG47929.1 - 0.087 12.7 0.5 13 5.7 0.1 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 CEG47929.1 - 0.35 10.6 1.8 19 4.9 0.3 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEG47929.1 - 0.5 10.3 2.8 6.6 6.6 0.0 2.7 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.27 CEG47933.1 - 2.8e-34 118.5 0.0 9e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 CEG47933.1 - 4.8e-31 107.8 24.8 1e-30 106.7 24.8 1.6 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 CEG47933.1 - 4.9e-08 33.1 0.2 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PDR_assoc PF08370.11 CEG47933.1 - 8.8e-07 28.6 0.3 2.8e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 CEG47933.1 - 2.6e-06 27.1 1.5 0.0037 17.0 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG47933.1 - 0.00011 22.4 0.0 0.63 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CEG47933.1 - 0.00013 22.3 0.0 0.34 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CEG47933.1 - 0.00021 20.9 0.2 0.8 9.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CEG47933.1 - 0.00034 20.1 0.1 0.19 11.1 0.0 2.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 CEG47933.1 - 0.00049 20.5 1.3 1.4 9.3 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 CEG47933.1 - 0.00068 19.5 2.6 2.3 7.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEG47933.1 - 0.0011 19.5 0.9 0.58 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEG47933.1 - 0.0011 19.0 0.5 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 CEG47933.1 - 0.0026 17.5 2.6 0.46 10.2 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG47933.1 - 0.0064 17.0 0.1 6.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG47933.1 - 0.0064 16.6 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CEG47933.1 - 0.019 14.3 0.2 0.74 9.1 0.1 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TsaE PF02367.17 CEG47933.1 - 0.027 14.5 1.1 0.65 10.0 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CEG47933.1 - 0.034 14.6 0.4 8.7 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PDR_CDR PF06422.12 CEG47933.1 - 0.044 13.7 0.5 0.15 11.9 0.5 1.9 1 0 0 1 1 1 0 CDR ABC transporter AAA_28 PF13521.6 CEG47933.1 - 0.062 13.6 0.1 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CEG47933.1 - 0.11 11.8 2.4 2.2 7.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin ABC2_membrane_3 PF12698.7 CEG47933.1 - 0.12 11.5 19.4 0.27 10.3 19.4 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_24 PF13479.6 CEG47933.1 - 0.15 11.8 2.3 2.3 7.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CEG47933.1 - 0.16 11.0 0.4 2.2 7.2 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CEG47933.1 - 0.17 11.5 0.4 20 4.7 0.0 2.5 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 CEG47933.1 - 0.23 11.0 2.3 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEG47933.1 - 0.32 10.9 3.0 2.1 8.2 0.5 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 CEG47933.1 - 0.49 10.7 2.8 15 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEG47933.1 - 1.3 9.0 6.0 8.9 6.3 0.8 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain HypA PF01155.19 CEG47934.1 - 0.098 12.7 0.9 0.14 12.2 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 CEG47934.1 - 0.1 12.6 0.9 0.13 12.3 0.9 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain Retrotran_gag_2 PF14223.6 CEG47936.1 - 6.5e-31 106.8 0.0 7.8e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type R3H PF01424.22 CEG47937.1 - 9.8e-16 57.5 0.1 9.8e-16 57.5 0.1 1.6 2 0 0 2 2 2 1 R3H domain SUZ PF12752.7 CEG47937.1 - 1.3e-09 38.7 0.5 1.3e-09 38.7 0.5 3.3 3 0 0 3 3 3 1 SUZ domain Ada3 PF10198.9 CEG47938.1 - 0.001 19.2 1.1 0.001 19.2 1.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3585 PF12130.8 CEG47938.1 - 0.025 14.7 1.5 0.06 13.5 1.5 1.7 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain Phage_antitermQ PF06530.12 CEG47938.1 - 0.071 13.0 0.2 2 8.3 0.1 2.6 2 0 0 2 2 2 0 Phage antitermination protein Q CaMBD PF02888.16 CEG47938.1 - 0.095 12.9 1.9 0.52 10.5 0.1 2.3 2 0 0 2 2 2 0 Calmodulin binding domain CENP-B_N PF04218.13 CEG47939.1 - 0.00013 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain BrkDBD PF09607.10 CEG47939.1 - 0.0007 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_28 PF13518.6 CEG47939.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain YrzK PF17449.2 CEG47939.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YrzK-like fn3 PF00041.21 CEG47940.1 - 3.5e-11 43.3 0.1 2e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain WD40 PF00400.32 CEG47940.1 - 1.7e-08 35.0 10.3 0.24 12.3 0.1 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat LysM PF01476.20 CEG47940.1 - 3e-07 30.4 0.0 8.6e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 LysM domain TPR_12 PF13424.6 CEG47940.1 - 0.0062 16.8 2.5 1.3 9.3 0.0 3.4 3 1 0 4 4 4 2 Tetratricopeptide repeat zf-C2HC_2 PF13913.6 CEG47940.1 - 0.013 15.4 6.2 0.18 11.7 3.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TMF_DNA_bd PF12329.8 CEG47940.1 - 0.2 11.6 10.7 23 5.0 0.1 4.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DM PF00751.18 CEG47940.1 - 0.21 11.5 6.7 0.056 13.4 2.4 2.2 2 0 0 2 2 2 0 DM DNA binding domain Sec7 PF01369.20 CEG47941.1 - 2.4e-58 196.9 0.3 4.4e-58 196.0 0.3 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEG47941.1 - 3.5e-10 40.0 1.2 3.5e-10 40.0 1.2 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.29 CEG47941.1 - 1.1e-06 29.1 0.8 4.1e-06 27.3 0.2 2.4 2 0 0 2 2 2 1 PH domain DUF2464 PF10240.9 CEG47941.1 - 1e-05 25.3 0.0 0.00034 20.3 0.0 2.3 1 1 0 1 1 1 1 Multivesicular body subunit 12 SPRY PF00622.28 CEG47942.1 - 4.8e-07 29.9 0.0 8.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain F-box PF00646.33 CEG47942.1 - 0.00044 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Peptidase_M3 PF01432.20 CEG47943.1 - 2.1e-64 218.5 0.2 2.3e-64 218.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M3 DUF505 PF04458.12 CEG47943.1 - 0.04 12.3 0.0 0.054 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Peptidase_M50B PF13398.6 CEG47943.1 - 0.083 12.5 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M3 PF01432.20 CEG47944.1 - 9e-40 137.3 0.3 1.4e-39 136.6 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M3 Mdv1 PF11542.8 CEG47945.1 - 0.094 12.7 0.0 3 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial division protein 1 Suv3_C_1 PF18147.1 CEG47946.1 - 7.9e-15 54.5 0.1 1.9e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 CEG47946.1 - 1.3e-13 50.6 0.2 3.5e-13 49.2 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CEG47946.1 - 7.1e-11 42.4 0.0 2.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 CEG47946.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Suv3 helical N-terminal domain HycI PF01750.18 CEG47947.1 - 0.099 12.5 5.7 0.23 11.3 0.9 2.9 2 1 0 2 2 2 0 Hydrogenase maturation protease UTP25 PF06862.12 CEG47948.1 - 1.8e-145 485.4 1.8 1.8e-145 485.4 1.8 1.6 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Adaptin_N PF01602.20 CEG47952.1 - 1.3e-128 429.9 10.4 1.6e-128 429.6 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CEG47952.1 - 3.7e-25 88.4 0.1 8.7e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CEG47952.1 - 3.8e-07 30.3 6.8 0.00037 20.6 1.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEG47952.1 - 0.025 14.8 0.2 2.5 8.6 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CEG47952.1 - 0.34 11.5 3.3 1.2 9.8 0.1 3.3 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region PPTA PF01239.22 CEG47953.1 - 1.2e-38 129.7 16.2 1.1e-08 34.6 0.2 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Cation_ATPase_C PF00689.21 CEG47956.1 - 3.3e-48 163.8 2.8 6e-48 163.0 0.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEG47956.1 - 6.9e-35 120.2 10.9 3.5e-23 82.1 0.3 3.8 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 CEG47956.1 - 4.5e-18 65.1 0.1 9.4e-18 64.1 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG47956.1 - 7.3e-16 59.1 0.4 4.8e-15 56.4 0.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEG47956.1 - 2.7e-14 52.6 0.0 8.2e-14 51.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus ATP_Ca_trans_C PF12424.8 CEG47956.1 - 8.7e-08 32.5 2.5 1.3e-07 31.9 0.7 2.2 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 CEG47956.1 - 8.8e-06 25.6 0.7 0.0011 18.7 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF962 PF06127.11 CEG47956.1 - 0.074 13.1 0.1 0.6 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF4999 PF16390.5 CEG47958.1 - 0.15 12.3 0.6 0.29 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function Laminin_G_3 PF13385.6 CEG47959.1 - 0.00017 21.8 2.9 0.0021 18.2 0.0 2.9 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily HHH_6 PF14579.6 CEG47959.1 - 0.077 13.3 0.0 0.98 9.7 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif VPR PF00522.18 CEG47960.1 - 0.3 11.1 1.3 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 VPR/VPX protein Ank_5 PF13857.6 CEG47961.1 - 1.5e-34 117.6 4.4 2.4e-11 43.6 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG47961.1 - 1.3e-33 115.4 1.8 1.8e-11 44.5 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CEG47961.1 - 1.2e-24 85.6 3.3 4.5e-07 30.0 0.1 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 CEG47961.1 - 8.6e-24 83.6 0.5 4.2e-05 24.0 0.0 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG47961.1 - 3.8e-22 76.0 2.3 4e-05 23.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat C1_1 PF00130.22 CEG47961.1 - 0.42 10.5 4.3 9.5 6.2 2.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_S49_N PF08496.10 CEG47961.1 - 1.1 9.3 3.9 2.2 8.3 3.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cytochrom_c3_2 PF14537.6 CEG47961.1 - 3.2 8.3 8.4 0.68 10.4 2.3 2.7 2 0 0 2 2 2 0 Cytochrome c3 ADP_PFK_GK PF04587.15 CEG47963.1 - 3e-99 332.5 0.3 3.7e-99 332.2 0.3 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region B12-binding PF02310.19 CEG47963.1 - 0.03 14.4 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain Nitro_FeMo-Co PF02579.17 CEG47963.1 - 0.099 13.0 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DUF4168 PF13767.6 CEG47963.1 - 0.28 12.4 2.6 0.26 12.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) GST_N_3 PF13417.6 CEG47964.1 - 6.4e-13 48.9 0.2 1.2e-12 48.0 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CEG47964.1 - 2.9e-10 40.2 4.1 3.1e-10 40.1 2.3 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_N_4 PF17172.4 CEG47964.1 - 3e-07 31.1 0.2 5.1e-06 27.2 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CEG47964.1 - 6.5e-07 29.6 0.1 1.2e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEG47964.1 - 0.00018 21.8 0.1 0.00048 20.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEG47964.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEG47964.1 - 0.041 14.1 0.0 0.12 12.6 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEG47964.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SH3_3 PF08239.11 CEG47965.1 - 0.0081 16.4 1.6 2.1 8.7 0.0 4.0 5 0 0 5 5 5 2 Bacterial SH3 domain GATase_5 PF13507.6 CEG47966.1 - 2e-95 318.8 0.0 3e-95 318.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CEG47966.1 - 6.3e-32 110.9 0.3 4.1e-15 56.2 0.1 2.9 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CEG47966.1 - 3.3e-21 75.4 0.1 6.6e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CEG47966.1 - 7.6e-11 42.4 0.0 2.3e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 CEG47966.1 - 0.00051 20.6 0.5 0.22 12.2 0.0 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain CLASP_N PF12348.8 CEG47969.1 - 6.7e-14 52.0 4.8 1.4e-08 34.6 0.1 4.7 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.22 CEG47969.1 - 3.8e-10 39.1 0.5 3.8 8.0 0.0 8.4 8 0 0 8 8 8 2 HEAT repeat TAN PF11640.8 CEG47969.1 - 0.0018 18.4 0.0 3.6 7.7 0.0 3.5 2 0 0 2 2 2 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 CEG47969.1 - 0.0085 16.6 0.9 13 6.4 0.2 5.1 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 CEG47969.1 - 0.015 15.4 10.8 0.083 12.9 0.1 5.7 7 2 1 8 8 8 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CEG47969.1 - 0.016 15.4 0.1 14 5.9 0.0 4.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CSTF_C PF14304.6 CEG47969.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal XPC-binding PF09280.11 CEG47969.1 - 0.39 10.5 1.6 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 XPC-binding domain Alpha_kinase PF02816.18 CEG47970.1 - 7.3e-53 179.4 0.0 1.2e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family MAGE_N PF12440.8 CEG47970.1 - 3.7 8.3 6.1 0.37 11.5 0.1 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal PBCV_basic_adap PF08789.10 CEG47972.1 - 0.0026 17.8 3.3 0.0084 16.2 3.3 1.9 1 0 0 1 1 1 1 PBCV-specific basic adaptor domain PALP PF00291.25 CEG47974.1 - 2.5e-40 138.7 0.9 5.6e-40 137.6 0.7 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 CEG47974.1 - 0.00024 20.8 0.0 0.00052 19.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 CEG47974.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 ACT domain WD40 PF00400.32 CEG47975.1 - 2.8e-41 138.7 23.0 6e-07 30.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG47975.1 - 4.2e-12 46.2 0.3 0.017 15.4 0.1 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG47975.1 - 4.6e-05 23.4 0.0 0.054 13.4 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEG47975.1 - 0.00014 20.9 0.3 1.3 7.9 0.0 4.0 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytotoxic PF09000.10 CEG47975.1 - 0.021 15.2 0.0 0.17 12.2 0.0 2.3 2 1 1 3 3 3 0 Cytotoxic CHAP PF05257.16 CEG47975.1 - 0.078 13.6 1.8 0.99 10.0 0.0 2.9 3 1 0 3 3 3 0 CHAP domain PH PF00169.29 CEG47979.1 - 3.9e-13 49.8 0.6 6.4e-13 49.1 0.6 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG47979.1 - 1.4e-08 34.9 1.9 1.9e-08 34.5 0.4 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CEG47979.1 - 1.9e-05 25.1 5.9 0.00052 20.4 3.8 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Glyco_transf_8C PF08437.10 CEG47979.1 - 0.029 14.4 2.4 0.055 13.6 2.4 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Amino_oxidase PF01593.24 CEG47980.1 - 1.2e-13 51.2 0.0 4.7e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEG47980.1 - 1.2e-09 38.3 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEG47980.1 - 0.0012 18.5 0.2 0.066 12.8 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEG47980.1 - 0.0026 17.8 0.1 0.039 13.9 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF3348 PF11828.8 CEG47981.1 - 0.01 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) T7SS_ESX_EspC PF10824.8 CEG47981.1 - 0.016 15.7 0.2 0.037 14.5 0.2 1.5 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Myosin_head PF00063.21 CEG47982.1 - 2.5e-211 703.5 0.0 7.9e-211 701.8 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 CEG47982.1 - 7.8e-14 51.6 16.3 2.1e-13 50.2 16.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger AAA_30 PF13604.6 CEG47982.1 - 0.0012 18.6 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG47982.1 - 0.002 18.5 0.0 0.0068 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG47982.1 - 0.0066 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG47982.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain FYVE_2 PF02318.16 CEG47982.1 - 0.015 15.5 7.3 0.051 13.8 7.3 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger GAF PF01590.26 CEG47982.1 - 0.099 13.3 0.0 0.39 11.4 0.0 2.0 1 0 0 1 1 1 0 GAF domain T2SSE PF00437.20 CEG47982.1 - 0.12 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Siva PF05458.12 CEG47982.1 - 0.14 11.8 3.4 0.28 10.8 3.4 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ATPase PF06745.13 CEG47982.1 - 0.14 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 KaiC DUF4428 PF14471.6 CEG47982.1 - 3.8 7.5 5.0 9.8 6.2 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) PX PF00787.24 CEG47983.1 - 2.4e-07 30.7 0.3 4.8e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 PX domain Rad50_zn_hook PF04423.14 CEG47983.1 - 0.29 11.0 1.8 0.65 9.9 0.0 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Hydrolase_4 PF12146.8 CEG47985.1 - 2.8e-52 177.4 0.0 3.4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG47985.1 - 2e-12 47.3 0.0 3.5e-12 46.5 0.0 1.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG47985.1 - 2.5e-08 34.8 0.0 4.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CEG47985.1 - 7.8e-07 28.8 0.0 0.039 13.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CEG47985.1 - 5.2e-05 23.2 0.3 0.088 12.6 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 CEG47985.1 - 0.0019 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CEG47985.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 CEG47985.1 - 0.031 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 CEG47985.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.6 1 1 1 2 2 2 0 Serine hydrolase DUF676 PF05057.14 CEG47985.1 - 0.054 13.0 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Say1_Mug180 PF10340.9 CEG47985.1 - 0.18 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Got1 PF04178.12 CEG47986.1 - 2.4e-24 85.9 13.4 3.1e-24 85.6 13.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ApoLp-III PF07464.11 CEG47986.1 - 0.00016 21.8 10.2 0.00022 21.4 10.2 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 CEG47986.1 - 0.00073 19.0 3.6 0.00073 19.0 3.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 CEG47986.1 - 0.052 13.4 5.6 0.082 12.8 5.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMP_2 PF06791.13 CEG47986.1 - 0.056 13.1 0.7 0.085 12.5 0.7 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF883 PF05957.13 CEG47986.1 - 0.095 13.3 6.2 0.22 12.1 6.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Fzo_mitofusin PF04799.13 CEG47986.1 - 0.13 11.8 2.5 0.3 10.6 2.5 1.6 1 0 0 1 1 1 0 fzo-like conserved region CCDC84 PF14968.6 CEG47986.1 - 0.14 11.8 3.5 0.17 11.5 3.5 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF4411 PF14367.6 CEG47986.1 - 0.44 10.5 3.1 0.67 9.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) ArnB_C PF18677.1 CEG47986.1 - 0.46 10.6 9.7 1.1 9.4 8.6 2.0 1 1 1 2 2 2 0 Archaellum regulatory network B, C-terminal domain Prominin PF05478.11 CEG47986.1 - 0.47 8.3 5.1 0.67 7.8 5.1 1.2 1 0 0 1 1 1 0 Prominin ApoO PF09769.9 CEG47986.1 - 0.54 10.2 4.5 1.4 8.9 1.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O MutS_IV PF05190.18 CEG47986.1 - 0.69 10.3 6.5 2.8 8.3 0.3 2.3 1 1 0 2 2 2 0 MutS family domain IV DUF948 PF06103.11 CEG47986.1 - 0.84 9.9 7.4 6.6 7.1 0.5 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 CEG47986.1 - 1.3 8.1 11.4 1.7 7.8 11.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Histidinol_dh PF00815.20 CEG47986.1 - 1.4 7.9 6.9 8.2 5.3 6.9 2.0 1 1 0 1 1 1 0 Histidinol dehydrogenase YtxH PF12732.7 CEG47986.1 - 1.7 9.2 17.8 14 6.3 12.5 2.4 1 1 1 2 2 2 0 YtxH-like protein DUF3464 PF11947.8 CEG47986.1 - 1.9 8.2 13.8 8.3 6.1 0.5 3.2 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 DIT1_PvcA PF05141.12 CEG47986.1 - 2.8 7.3 8.7 3.9 6.8 8.7 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Pinin_SDK_memA PF04696.13 CEG47986.1 - 6.3 6.9 14.1 0.7 9.9 9.9 1.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF2070 PF09843.9 CEG47986.1 - 9.7 4.3 10.1 0.59 8.4 4.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3450 PF11932.8 CEG47986.1 - 9.9 5.4 12.1 2.9 7.1 9.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tyr-DNA_phospho PF06087.12 CEG47987.1 - 4.1e-07 29.2 0.0 4.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Tyr-DNA_phospho PF06087.12 CEG47989.1 - 2.6e-71 240.8 0.0 4.2e-36 124.8 0.0 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase Cas_Cas1 PF01867.16 CEG47991.1 - 0.12 11.5 3.0 0.17 11.0 3.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 PseudoU_synth_2 PF00849.22 CEG47992.1 - 1.4e-25 90.3 0.0 2.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 CEG47992.1 - 0.13 12.1 0.3 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Mut7-C ubiquitin Aminotran_1_2 PF00155.21 CEG47993.1 - 2e-54 185.1 0.0 3.2e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG47993.1 - 0.0022 17.0 0.0 0.072 12.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEG47993.1 - 0.02 13.4 0.1 0.085 11.4 0.1 2.0 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 CEG47993.1 - 0.13 11.0 0.0 1 8.1 0.0 2.3 2 1 0 2 2 2 0 Alanine-glyoxylate amino-transferase zf-HC5HC2H_2 PF13832.6 CEG47994.1 - 5.9e-20 71.5 7.2 5.9e-20 71.5 7.2 3.8 4 0 0 4 4 4 1 PHD-zinc-finger like domain ResIII PF04851.15 CEG47994.1 - 8.6e-18 64.9 0.0 2.4e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEG47994.1 - 1.3e-17 64.2 0.8 3.5e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 CEG47994.1 - 4.2e-16 59.0 1.6 4.2e-16 59.0 1.6 4.5 3 1 2 5 5 5 1 PHD-like zinc-binding domain DEAD PF00270.29 CEG47994.1 - 4.2e-15 55.9 0.0 1.8e-14 53.9 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.6 CEG47994.1 - 9e-11 41.2 3.9 9e-11 41.2 3.9 3.9 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 CEG47994.1 - 1.6e-09 37.5 34.7 1.6e-09 37.5 6.4 5.0 4 0 0 4 4 4 2 PHD-finger zf-RanBP PF00641.18 CEG47994.1 - 8.2e-06 25.0 3.6 3.7e-05 22.9 3.6 2.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SWI2_SNF2 PF18766.1 CEG47994.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ELMO_CED12 PF04727.13 CEG47995.1 - 9.9e-21 74.6 0.0 2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DIX PF00778.17 CEG47995.1 - 6.3e-05 22.7 0.0 0.00022 21.0 0.0 1.9 1 1 1 2 2 2 1 DIX domain Itfg2 PF15907.5 CEG47996.1 - 8.5e-15 54.6 2.6 4.1e-11 42.5 0.0 3.6 2 1 1 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 CEG47996.1 - 1.1e-05 25.5 3.5 1.7 8.7 0.1 4.4 4 1 1 5 5 5 3 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 CEG47996.1 - 0.00021 20.9 1.3 0.48 9.8 0.0 3.7 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 1 BBS2_N PF14781.6 CEG47996.1 - 0.002 18.0 0.1 0.077 12.9 0.0 3.1 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, N-terminal PQQ_3 PF13570.6 CEG47996.1 - 0.048 14.2 0.0 1 9.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain FG-GAP PF01839.23 CEG47996.1 - 0.057 13.6 0.6 0.19 11.9 0.6 1.8 1 0 0 1 1 1 0 FG-GAP repeat PQQ_2 PF13360.6 CEG47996.1 - 0.091 12.3 0.1 0.66 9.5 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain VCBS PF13517.6 CEG47996.1 - 0.1 13.2 0.4 0.72 10.5 0.1 2.6 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PP2 PF14299.6 CEG47996.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Phloem protein 2 P5CR_dimer PF14748.6 CEG47997.1 - 5.7e-36 122.9 0.2 1.3e-35 121.8 0.2 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CEG47997.1 - 4.3e-12 46.4 1.2 9.4e-12 45.4 1.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 CEG47997.1 - 7.4e-08 31.7 0.8 1.1e-07 31.2 0.8 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 CEG47997.1 - 9.6e-06 25.3 0.2 1.6e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CEG47997.1 - 0.00043 20.3 0.2 0.00069 19.6 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 CEG47997.1 - 0.03 14.5 1.2 0.07 13.3 0.9 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GrpE PF01025.19 CEG47998.1 - 1.1e-45 155.2 2.2 1.4e-45 155.0 2.2 1.1 1 0 0 1 1 1 1 GrpE EF-hand_7 PF13499.6 CEG47998.1 - 0.013 16.0 0.3 0.033 14.7 0.2 2.0 1 1 0 1 1 1 0 EF-hand domain pair UCH PF00443.29 CEG47999.1 - 1.5e-41 142.6 0.3 2e-41 142.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEG47999.1 - 0.00053 19.7 6.8 0.016 14.9 6.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PPR_2 PF13041.6 CEG48000.1 - 6.3e-17 61.5 0.0 1.6e-11 44.2 0.0 4.6 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CEG48000.1 - 2.4e-16 59.6 0.1 6.2e-11 42.2 0.0 4.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEG48000.1 - 1.5e-14 53.3 0.1 3.6e-07 29.8 0.0 4.5 4 0 0 4 4 4 2 PPR repeat DNA_pol_A_exo1 PF01612.20 CEG48000.1 - 7.7e-14 51.8 0.0 5.4e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease PPR PF01535.20 CEG48000.1 - 4.3e-09 36.0 0.9 0.00098 19.2 0.0 5.9 6 0 0 6 6 6 1 PPR repeat TyeA PF09059.10 CEG48000.1 - 0.024 14.7 0.4 2.3 8.4 0.0 3.4 2 0 0 2 2 2 0 TyeA PPR_long PF17177.4 CEG48000.1 - 0.049 13.0 2.3 0.48 9.8 0.1 3.5 3 1 1 4 4 4 0 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 CEG48000.1 - 0.087 12.7 0.1 1 9.2 0.1 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF4539 PF15072.6 CEG48001.1 - 3.3e-23 81.5 0.0 6.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Dynactin_p22 PF07426.11 CEG48003.1 - 8.8e-26 90.7 9.0 1e-25 90.6 9.0 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 DUF3604 PF12228.8 CEG48003.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Filament PF00038.21 CEG48003.1 - 0.13 11.8 11.0 0.22 11.0 9.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF1421 PF07223.11 CEG48003.1 - 0.16 11.8 0.1 3 7.8 0.0 2.7 3 0 0 3 3 3 0 UBA-like domain (DUF1421) Baculo_p24 PF05073.12 CEG48003.1 - 0.33 10.7 4.9 0.32 10.8 2.3 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Spc24 PF08286.11 CEG48003.1 - 0.33 11.2 5.2 1.1 9.5 2.4 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 CEG48003.1 - 0.91 9.6 7.1 3.3 7.8 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med21 PF11221.8 CEG48003.1 - 2.1 8.6 13.1 3.6 7.8 13.1 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex bZIP_1 PF00170.21 CEG48004.1 - 0.13 12.3 0.9 0.26 11.4 0.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 CEG48004.1 - 0.19 11.9 1.0 0.4 10.8 1.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CEG48006.1 - 0.012 15.7 1.8 0.021 14.9 1.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor HisKA PF00512.25 CEG48006.1 - 0.023 14.7 0.5 0.074 13.1 0.5 1.9 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain bZIP_2 PF07716.15 CEG48006.1 - 0.2 11.7 5.5 0.41 10.8 5.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper SLM4 PF16818.5 CEG48009.1 - 0.0085 16.1 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein SLM4 TORC_M PF12885.7 CEG48009.1 - 0.09 12.7 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Retrotran_gag_2 PF14223.6 CEG48010.1 - 3.8e-24 84.9 0.2 5.8e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG48010.1 - 0.0044 17.0 6.0 0.0079 16.2 6.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEG48010.1 - 0.03 14.1 7.8 0.056 13.3 7.8 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3192 PF11399.8 CEG48010.1 - 0.031 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) DUF4219 PF13961.6 CEG48010.1 - 0.031 13.9 0.9 0.078 12.7 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_3 PF13917.6 CEG48010.1 - 0.034 14.1 0.9 0.034 14.1 0.9 1.7 2 0 0 2 2 2 0 Zinc knuckle DUF3895 PF13034.6 CEG48010.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) CLIP1_ZNF PF16641.5 CEG48010.1 - 2 8.4 6.1 3.2 7.7 6.1 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Use1 PF09753.9 CEG48011.1 - 1.1e-18 67.9 3.4 1.3e-18 67.6 3.4 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 UvrC_HhH_N PF08459.11 CEG48011.1 - 0.0008 19.3 0.4 0.0013 18.7 0.4 1.3 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal Orf78 PF06024.12 CEG48011.1 - 0.012 15.9 0.6 0.025 14.9 0.6 1.7 1 1 0 1 1 1 0 Orf78 (ac78) KASH_CCD PF14662.6 CEG48011.1 - 1 9.1 9.4 0.6 9.9 2.0 2.8 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Ephrin_rec_like PF07699.13 CEG48012.1 - 1.9e-11 43.6 34.5 2.1e-06 27.4 3.3 4.7 1 1 3 4 4 4 4 Putative ephrin-receptor like LBP_BPI_CETP PF01273.25 CEG48012.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Nup192 PF11894.8 CEG48013.1 - 2.4e-106 356.5 3.8 1.5e-104 350.6 3.8 2.9 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 2OG-FeII_Oxy_3 PF13640.6 CEG48014.1 - 6.2e-10 39.8 0.1 1.3e-09 38.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4177 PF13783.6 CEG48015.1 - 0.041 14.2 0.2 0.068 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) UPF0767 PF15990.5 CEG48015.1 - 0.14 12.3 3.7 11 6.3 3.2 2.9 1 1 1 2 2 2 0 UPF0767 family SPT6_acidic PF14632.6 CEG48015.1 - 7.5 7.2 14.7 1 10.0 8.5 2.1 1 1 1 2 2 2 0 Acidic N-terminal SPT6 SCP2 PF02036.17 CEG48016.1 - 1.1e-48 163.9 5.6 3e-25 88.7 0.4 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CEG48016.1 - 1.2e-14 54.7 2.8 3.1e-08 33.9 0.4 2.1 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal DUF1754 PF08555.10 CEG48016.1 - 0.15 12.9 2.1 6 7.7 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) ORC5_C PF14630.6 CEG48018.1 - 9.6e-46 156.6 0.2 1.3e-45 156.2 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CEG48018.1 - 0.0047 17.3 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG48018.1 - 0.023 15.0 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CEG48019.1 - 1.2e-49 169.1 0.0 3.7e-49 167.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48019.1 - 8.9e-18 64.5 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1752 PF08550.10 CEG48019.1 - 7.6e-08 32.1 1.2 1.8e-07 30.9 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) eIF3g PF12353.8 CEG48019.1 - 0.16 12.4 0.0 0.16 12.4 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Ssl1 PF04056.14 CEG48020.1 - 7.5e-65 218.4 0.0 9.8e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CEG48020.1 - 1e-09 39.0 0.0 2.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CEG48020.1 - 3.6e-05 24.1 0.0 6.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 CEG48020.1 - 4.8e-05 23.0 0.1 8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 C1_4 PF07975.12 CEG48020.1 - 0.013 15.7 7.3 0.013 15.7 7.3 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain FDC-SP PF15215.6 CEG48021.1 - 0.076 13.6 0.1 0.2 12.2 0.0 1.6 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide WD40 PF00400.32 CEG48022.1 - 3.8e-30 103.5 35.1 0.0005 20.8 0.2 17.5 15 1 1 16 16 16 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48022.1 - 3e-23 81.9 0.1 0.00099 19.4 0.0 9.5 7 2 2 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 CEG48022.1 - 5e-21 74.3 0.3 5.9e-08 32.5 0.0 3.6 3 0 0 3 3 3 3 HELP motif EF-hand_6 PF13405.6 CEG48022.1 - 3.1e-08 32.9 0.2 0.0053 16.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEG48022.1 - 5.6e-08 31.8 0.1 0.0072 15.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CEG48022.1 - 8.1e-07 29.4 0.2 2.5e-06 27.8 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair Ge1_WD40 PF16529.5 CEG48022.1 - 7.6e-05 21.8 0.7 15 4.4 0.0 6.0 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_5 PF13202.6 CEG48022.1 - 8e-05 21.9 0.3 0.025 14.0 0.0 2.8 2 0 0 2 2 2 1 EF hand IKI3 PF04762.12 CEG48022.1 - 0.029 12.4 0.1 10 4.0 0.0 3.6 4 1 1 5 5 5 0 IKI3 family Nucleoporin_N PF08801.11 CEG48022.1 - 0.057 12.1 0.1 5.1 5.7 0.1 3.7 4 0 0 4 4 4 0 Nup133 N terminal like EF-hand_8 PF13833.6 CEG48022.1 - 0.093 12.6 0.6 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair THOC7 PF05615.13 CEG48023.1 - 2.9 8.2 10.1 3.2 8.0 4.8 3.0 2 0 0 2 2 2 0 Tho complex subunit 7 bZIP_2 PF07716.15 CEG48024.1 - 4.8e-08 33.0 9.7 1.2e-07 31.7 9.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEG48024.1 - 4.3e-06 26.7 9.1 1.2e-05 25.3 9.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor Thr_synth_N PF14821.6 CEG48026.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonine synthase N terminus Pex14_N PF04695.13 CEG48027.1 - 0.041 14.5 0.9 0.046 14.4 0.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CSG2 PF16965.5 CEG48027.1 - 0.17 10.8 1.3 0.19 10.7 1.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Kei1 PF08552.11 CEG48027.1 - 0.45 10.4 3.8 0.55 10.1 3.8 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RNA_pol_Rpc4 PF05132.14 CEG48027.1 - 0.74 10.2 7.3 0.87 10.0 7.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CEG48027.1 - 1.1 7.5 13.0 1.1 7.4 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CEG48027.1 - 1.9 7.9 18.8 2.2 7.6 18.8 1.1 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 CEG48027.1 - 1.9 7.2 13.6 2.1 7.1 13.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CEG48027.1 - 2.1 8.3 4.3 2.2 8.3 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 CEG48027.1 - 2.3 7.9 3.6 2.4 7.8 3.6 1.2 1 0 0 1 1 1 0 Connexin Macoilin PF09726.9 CEG48027.1 - 4.9 5.6 13.3 5.2 5.5 13.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF1935 PF09149.10 CEG48027.1 - 5.2 7.5 10.5 2.5e+02 2.1 10.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1935) MCM_bind PF09739.9 CEG48027.1 - 6.5 5.1 11.8 7.2 4.9 11.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zip PF02535.22 CEG48027.1 - 7.3 5.7 9.7 7.5 5.7 9.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CEG48027.1 - 9.1 4.9 13.2 9.8 4.8 13.2 1.1 1 0 0 1 1 1 0 Presenilin RVT_2 PF07727.14 CEG48029.1 - 1.4e-32 113.2 0.0 2.1e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 CEG48029.1 - 0.036 14.1 0.6 0.062 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 CEG48029.1 - 0.064 13.1 0.3 0.14 12.1 0.2 1.5 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor NleF_casp_inhib PF16809.5 CEG48029.1 - 0.085 12.8 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor Pre-PUA PF17832.1 CEG48029.1 - 0.11 13.2 0.2 0.3 11.8 0.2 1.7 1 0 0 1 1 1 0 Pre-PUA-like domain ZapB PF06005.12 CEG48029.1 - 0.13 12.7 1.4 0.28 11.7 1.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 CEG48029.1 - 0.16 12.1 2.1 0.28 11.3 2.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4200 PF13863.6 CEG48029.1 - 0.16 12.4 4.6 0.3 11.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 CEG48029.1 - 0.21 11.7 2.5 2.1 8.4 0.2 2.2 1 1 1 2 2 2 0 DivIVA protein Mito_carr PF00153.27 CEG48030.1 - 2.8e-69 229.1 2.3 2.7e-27 94.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEG48030.1 - 0.015 14.4 0.7 2.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Rab5ip PF07019.12 CEG48030.1 - 9.1 7.0 6.2 14 6.4 0.0 3.4 3 1 1 4 4 4 0 Rab5-interacting protein (Rab5ip) TPR_2 PF07719.17 CEG48031.1 - 2.3e-07 30.4 12.9 0.71 10.1 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG48031.1 - 3e-07 30.6 23.6 0.0011 19.2 2.4 6.3 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG48031.1 - 6.8e-07 29.7 11.1 0.086 13.4 0.1 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG48031.1 - 2.5e-06 27.8 15.6 5.9 8.0 0.0 7.8 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48031.1 - 1e-05 25.1 0.1 0.039 13.6 0.0 4.9 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 CEG48031.1 - 9.4e-05 22.3 3.3 0.75 10.2 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG48031.1 - 0.082 13.3 5.4 13 6.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEG48031.1 - 0.63 10.7 11.5 15 6.3 0.0 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG48031.1 - 4.7 7.5 13.8 37 4.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Transket_pyr PF02779.24 CEG48032.1 - 1.1e-58 197.9 0.0 1.7e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CEG48032.1 - 1.9e-49 168.3 0.0 2.6e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CEG48032.1 - 1e-40 138.9 0.0 3.5e-40 137.2 0.0 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal L27_2 PF09045.10 CEG48032.1 - 0.14 12.1 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 L27_2 HHH_3 PF12836.7 CEG48036.1 - 9.4e-32 109.1 0.2 2.2e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.23 CEG48036.1 - 8.8e-16 56.9 0.1 4.4e-05 23.1 0.0 4.2 4 0 0 4 4 4 3 Helix-hairpin-helix motif PsbU PF06514.11 CEG48036.1 - 1.3e-10 41.1 0.0 7.8e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.6 CEG48036.1 - 2e-09 37.9 0.0 0.06 14.0 0.0 4.3 4 0 0 4 4 4 2 Helix-hairpin-helix domain HHH_2 PF12826.7 CEG48036.1 - 1.6e-06 28.1 0.1 0.089 12.9 0.0 3.2 3 1 1 4 4 4 2 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 CEG48036.1 - 1.1e-05 25.1 0.0 4.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_8 PF14716.6 CEG48036.1 - 0.00014 22.1 0.1 0.76 10.2 0.0 3.7 2 1 1 3 3 3 2 Helix-hairpin-helix domain HHH_6 PF14579.6 CEG48036.1 - 0.028 14.7 0.0 7 7.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.8 CEG48036.1 - 0.058 13.6 0.0 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Pathogenicity locus Exo_endo_phos_2 PF14529.6 CEG48036.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DNA_pol_lambd_f PF10391.9 CEG48036.1 - 0.13 12.1 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Pkinase PF00069.25 CEG48037.1 - 7.3e-51 173.1 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48037.1 - 2.3e-37 128.7 0.0 3.6e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG48037.1 - 0.0031 16.4 0.2 0.0092 14.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase OSR1_C PF12202.8 CEG48037.1 - 0.017 15.3 1.1 0.05 13.8 0.0 2.3 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain DUF1640 PF07798.11 CEG48037.1 - 0.035 14.2 1.8 0.078 13.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ACCA PF03255.14 CEG48037.1 - 0.079 12.8 2.0 1.4 8.8 2.0 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FAM76 PF16046.5 CEG48037.1 - 0.1 11.9 3.3 0.19 11.1 3.3 1.4 1 0 0 1 1 1 0 FAM76 protein PB1-F2 PF11986.8 CEG48037.1 - 0.21 11.8 1.1 0.81 9.9 0.6 2.2 2 0 0 2 2 2 0 Influenza A Proapoptotic protein AAA_5 PF07728.14 CEG48038.1 - 1.4e-118 391.2 0.0 2.2e-23 82.8 0.0 10.0 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CEG48038.1 - 1.3e-40 137.9 9.7 4.6e-14 52.5 0.1 7.1 6 0 0 6 6 5 4 Midasin AAA lid domain AAA_7 PF12775.7 CEG48038.1 - 9.5e-27 93.7 0.2 0.00013 21.6 0.3 6.6 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CEG48038.1 - 4.4e-25 87.8 0.2 1.9e-24 85.8 0.2 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 CEG48038.1 - 2.8e-24 86.4 12.5 0.008 16.6 0.2 8.9 7 1 1 8 8 7 6 AAA ATPase domain AAA PF00004.29 CEG48038.1 - 7.3e-23 81.4 2.0 0.00075 19.9 0.0 8.0 8 0 0 8 8 6 4 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 CEG48038.1 - 1.4e-21 76.7 0.0 1.4e-05 25.0 0.0 7.5 7 1 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CEG48038.1 - 2.2e-20 72.9 0.0 0.00034 20.7 0.0 6.6 6 0 0 6 6 6 5 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CEG48038.1 - 1.7e-18 67.2 3.9 0.01 16.1 0.0 8.6 8 0 0 8 8 7 4 AAA domain AAA_6 PF12774.7 CEG48038.1 - 2.7e-17 62.7 0.8 0.0004 19.5 0.0 8.7 9 0 0 9 9 9 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CEG48038.1 - 2.3e-14 54.0 4.0 0.21 12.1 0.0 7.9 7 0 0 7 7 6 3 AAA domain Sigma54_activat PF00158.26 CEG48038.1 - 7.8e-14 51.7 0.0 0.091 12.5 0.0 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain TsaE PF02367.17 CEG48038.1 - 5.5e-13 49.0 2.1 0.18 11.8 0.0 6.3 7 0 0 7 7 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEG48038.1 - 1.5e-12 47.7 0.0 0.072 13.1 0.0 8.0 8 1 1 9 9 6 2 AAA domain ABC_tran PF00005.27 CEG48038.1 - 1.2e-10 42.1 8.2 0.42 11.1 0.0 8.0 7 0 0 7 7 7 2 ABC transporter AAA_28 PF13521.6 CEG48038.1 - 2.3e-10 41.0 6.5 0.48 10.7 0.0 7.1 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.6 CEG48038.1 - 4.8e-10 39.3 2.9 0.7 9.4 0.0 6.6 6 0 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 CEG48038.1 - 1.3e-09 38.4 0.7 1.6 9.1 0.0 6.6 6 0 0 6 6 6 1 RNA helicase NACHT PF05729.12 CEG48038.1 - 1.3e-09 38.2 0.3 0.98 9.3 0.1 6.6 6 0 0 6 6 6 2 NACHT domain Mg_chelatase PF01078.21 CEG48038.1 - 2.2e-09 37.0 3.4 0.05 13.0 0.0 7.5 6 1 0 6 6 6 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CEG48038.1 - 7.3e-09 35.2 0.5 3.2 7.0 0.0 6.2 6 0 0 6 6 6 2 Zeta toxin AAA_19 PF13245.6 CEG48038.1 - 3.1e-08 34.1 4.1 0.31 11.4 0.0 7.1 8 0 0 8 8 6 1 AAA domain T2SSE PF00437.20 CEG48038.1 - 3.7e-08 32.8 2.7 0.05 12.7 0.0 5.6 5 0 0 5 5 5 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CEG48038.1 - 5.3e-08 32.9 1.0 2.2 8.2 0.1 6.2 5 0 0 5 5 5 2 RsgA GTPase Rad17 PF03215.15 CEG48038.1 - 7.3e-08 32.5 3.8 0.11 12.4 0.0 5.9 6 0 0 6 6 6 2 Rad17 P-loop domain PduV-EutP PF10662.9 CEG48038.1 - 1.4e-07 31.3 0.4 0.62 9.8 0.0 6.1 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_8 PF12780.7 CEG48038.1 - 1.9e-07 30.7 0.1 2.3 7.5 0.0 6.1 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_33 PF13671.6 CEG48038.1 - 2.7e-07 30.9 6.2 1.2 9.3 0.0 7.5 7 1 0 7 7 6 1 AAA domain AAA_29 PF13555.6 CEG48038.1 - 5.4e-07 29.2 0.0 0.91 9.3 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 CEG48038.1 - 7.6e-07 29.3 1.7 1.3 9.2 0.0 5.8 7 0 0 7 7 5 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CEG48038.1 - 6.2e-06 26.1 0.7 0.24 11.1 0.0 4.5 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CEG48038.1 - 1.2e-05 25.1 7.1 0.14 11.9 0.0 6.1 6 0 0 6 6 6 1 IstB-like ATP binding protein VWA_2 PF13519.6 CEG48038.1 - 1.4e-05 25.7 2.1 6.5e-05 23.5 0.5 3.2 2 0 0 2 2 1 1 von Willebrand factor type A domain RuvB_N PF05496.12 CEG48038.1 - 3.8e-05 23.5 3.2 21 4.8 0.0 7.0 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain tRNA_lig_kinase PF08303.11 CEG48038.1 - 8.6e-05 22.7 0.6 0.68 10.0 0.1 4.1 3 0 0 3 3 3 1 tRNA ligase kinase domain TniB PF05621.11 CEG48038.1 - 0.00019 20.9 1.4 5 6.5 0.0 5.7 7 0 0 7 7 6 0 Bacterial TniB protein ATPase_2 PF01637.18 CEG48038.1 - 0.0002 21.4 10.2 0.071 13.0 0.0 6.5 7 0 0 7 7 6 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 CEG48038.1 - 0.0019 17.8 0.7 25 4.4 0.1 5.2 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain Roc PF08477.13 CEG48038.1 - 0.0052 17.0 3.2 47 4.2 0.0 5.8 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEG48038.1 - 0.012 15.2 1.9 26 4.4 0.0 5.1 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 CEG48038.1 - 0.026 13.9 0.8 9.5 5.5 0.0 4.2 4 0 0 4 4 3 0 KaiC PhoH PF02562.16 CEG48038.1 - 0.028 13.9 0.2 5.5 6.4 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein MMR_HSR1 PF01926.23 CEG48038.1 - 0.037 14.1 6.0 15 5.7 0.0 6.0 8 0 0 8 8 4 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CEG48038.1 - 0.061 13.2 5.1 75 3.2 0.0 5.6 6 0 0 6 6 5 0 NTPase Frankia_peptide PF14407.6 CEG48038.1 - 0.57 10.2 3.7 28 4.8 0.0 3.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Tsg PF04668.12 CEG48039.1 - 0.037 14.7 2.8 0.042 14.5 2.8 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region ubiquitin PF00240.23 CEG48040.1 - 0.0027 17.4 0.1 0.055 13.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family zf-C2H2_3rep PF18868.1 CEG48040.1 - 0.022 15.4 0.0 0.034 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats NYD-SP28 PF14772.6 CEG48042.1 - 9.4e-13 48.1 14.5 9.4e-13 48.1 14.5 4.7 2 2 0 3 3 3 1 Sperm tail NYD-SP28_assoc PF14775.6 CEG48042.1 - 6.5e-07 29.4 1.1 6.5e-07 29.4 1.1 3.2 2 1 2 4 4 4 1 Sperm tail C-terminal domain DUF3584 PF12128.8 CEG48042.1 - 0.054 11.0 41.2 0.069 10.7 41.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SNF2_N PF00176.23 CEG48043.1 - 1e-61 208.6 0.5 2.2e-61 207.5 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 CEG48043.1 - 2.7e-24 84.8 75.2 3.5e-08 33.2 9.0 6.8 5 1 1 6 6 6 4 PHD-finger Helicase_C PF00271.31 CEG48043.1 - 4.3e-17 62.4 0.0 1.4e-16 60.8 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CEG48043.1 - 1.3e-16 60.4 0.0 3.7e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 CEG48043.1 - 2.9e-11 43.5 3.1 2.9e-11 43.5 3.1 7.7 5 2 3 8 8 7 3 PHD-like zinc-binding domain Chromo PF00385.24 CEG48043.1 - 8.3e-11 41.6 0.0 1.2e-05 25.1 0.0 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H_2 PF13832.6 CEG48043.1 - 1.7e-08 34.6 2.9 1.7e-08 34.6 2.9 7.0 4 2 3 7 7 6 3 PHD-zinc-finger like domain ResIII PF04851.15 CEG48043.1 - 2.8e-08 33.9 0.0 7.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEG48043.1 - 1e-06 28.2 0.0 9.1e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PDZ_6 PF17820.1 CEG48043.1 - 2e-05 24.3 0.1 4.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PHD_2 PF13831.6 CEG48043.1 - 3.3e-05 23.3 29.7 0.0017 17.8 1.1 5.2 4 0 0 4 4 4 3 PHD-finger PDZ PF00595.24 CEG48043.1 - 0.00011 22.5 0.2 0.00029 21.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain DEAD PF00270.29 CEG48043.1 - 0.00083 19.2 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEG48043.1 - 0.00087 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Hemerythrin PF01814.23 CEG48044.1 - 0.033 14.8 0.0 0.46 11.1 0.0 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain FAM177 PF14774.6 CEG48045.1 - 5.2e-10 39.7 0.0 7.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 FAM177 family Urocanase_C PF17392.2 CEG48045.1 - 0.067 12.6 0.4 0.098 12.1 0.4 1.2 1 0 0 1 1 1 0 Urocanase C-terminal domain DUF1682 PF07946.14 CEG48045.1 - 9.1 5.4 9.9 14 4.7 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PGP_phosphatase PF09419.10 CEG48046.1 - 1.8e-39 135.0 0.0 2.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CEG48046.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LMSTEN PF07988.12 CEG48046.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 LMSTEN motif DUF4208 PF13907.6 CEG48047.1 - 3.1e-07 30.7 0.4 1.1e-06 29.0 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) CHDCT2 PF08074.11 CEG48047.1 - 0.00044 20.5 0.0 0.0023 18.1 0.0 2.3 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain Vpu PF00558.19 CEG48047.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.5 3 0 0 3 3 3 0 Vpu protein AF-4 PF05110.13 CEG48047.1 - 0.4 8.7 46.2 0.096 10.8 23.4 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein FOP_dimer PF09398.10 CEG48048.1 - 4.4e-06 26.9 0.0 9.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain TMEM70 PF06979.12 CEG48049.1 - 2.3e-29 102.5 0.3 3.3e-29 102.0 0.3 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex WD40 PF00400.32 CEG48053.1 - 1.3e-09 38.5 3.8 0.00077 20.2 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DJ-1_PfpI PF01965.24 CEG48056.1 - 1.3e-22 80.4 0.6 1.7e-22 80.0 0.6 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family XisH PF08814.10 CEG48056.1 - 0.0093 16.1 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 1 XisH protein DJ-1_PfpI PF01965.24 CEG48057.1 - 1.8e-24 86.4 0.2 8.3e-12 45.2 0.1 2.0 1 1 1 2 2 2 2 DJ-1/PfpI family Kelch_3 PF13415.6 CEG48058.1 - 6.7e-39 131.5 8.3 1.2e-06 28.7 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CEG48058.1 - 4e-30 103.1 0.1 1.2e-09 37.6 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CEG48058.1 - 9.3e-30 102.4 5.0 5.4e-08 32.7 0.0 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CEG48058.1 - 8.4e-27 92.1 2.7 4.2e-06 26.5 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CEG48058.1 - 1.5e-25 88.6 0.0 4.9e-07 29.8 0.0 5.5 2 1 3 5 5 5 5 Kelch motif Kelch_5 PF13854.6 CEG48058.1 - 5.2e-24 83.8 0.3 1.6e-07 31.2 0.0 5.3 6 0 0 6 6 6 4 Kelch motif BTB PF00651.31 CEG48058.1 - 6.7e-21 74.6 3.2 1e-18 67.6 0.2 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF2870 PF11069.8 CEG48059.1 - 1.3e-39 134.5 0.2 2e-39 133.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) WASH-7_mid PF14744.6 CEG48060.1 - 1.2e-147 491.6 5.7 2.2e-147 490.7 5.7 1.5 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 CEG48060.1 - 5.1e-127 424.8 0.0 2e-126 422.8 0.0 1.8 1 1 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 CEG48060.1 - 3.8e-64 215.6 5.0 8.6e-64 214.4 5.0 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Pkinase_Tyr PF07714.17 CEG48061.1 - 1.4e-27 96.7 0.0 2.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG48061.1 - 3.8e-22 78.9 0.0 1e-21 77.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Baculo_11_kDa PF06143.11 CEG48061.1 - 0.0014 18.2 0.3 0.0032 17.0 0.3 1.6 1 0 0 1 1 1 1 Baculovirus 11 kDa family Shisa PF13908.6 CEG48061.1 - 0.012 15.9 0.3 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator m04gp34like PF12216.8 CEG48061.1 - 0.05 13.2 3.4 2.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Immune evasion protein SMN PF06003.12 CEG48062.1 - 1.1e-05 24.9 7.9 3.1e-05 23.4 4.7 2.5 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) A_deaminase PF00962.22 CEG48062.1 - 0.033 13.5 0.3 0.045 13.1 0.3 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase COMM_domain PF07258.14 CEG48064.1 - 3.9e-16 58.9 0.7 8e-16 57.9 0.7 1.5 1 0 0 1 1 1 1 COMM domain Spo0A_C PF08769.11 CEG48064.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal HABP4_PAI-RBP1 PF04774.15 CEG48067.1 - 4.9e-13 49.9 11.8 4.9e-13 49.9 11.8 2.8 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family LRIF1 PF15741.5 CEG48067.1 - 0.32 9.5 2.7 0.4 9.2 2.7 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 MORN PF02493.20 CEG48068.1 - 2.3e-39 130.9 81.8 4.9e-05 23.0 0.5 12.2 13 0 0 13 13 13 11 MORN repeat Pet20 PF08692.10 CEG48073.1 - 1.7 9.4 5.1 3.3 8.5 4.1 1.9 1 1 0 2 2 2 0 Mitochondrial protein Pet20 EIIBC-GUT_N PF03612.14 CEG48073.1 - 2.8 7.7 5.7 5.2 6.8 5.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Cluap1 PF10234.9 CEG48074.1 - 3.9e-95 318.3 15.8 3.9e-95 318.3 15.8 1.5 2 0 0 2 2 2 1 Clusterin-associated protein-1 BORCS8 PF10167.9 CEG48074.1 - 0.14 12.1 3.3 0.069 13.1 0.7 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 SPACA9 PF15120.6 CEG48074.1 - 1 9.1 7.5 5.7 6.7 7.5 2.1 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 Prominin PF05478.11 CEG48074.1 - 1.1 7.1 10.2 0.26 9.2 6.6 1.6 1 1 1 2 2 2 0 Prominin Pkinase PF00069.25 CEG48076.1 - 3.4e-69 233.1 0.0 4.8e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48076.1 - 2.3e-37 128.7 0.0 3.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CEG48076.1 - 1.5e-10 41.2 0.2 6e-10 39.3 0.2 2.0 1 0 0 1 1 1 1 C2 domain FYVE PF01363.21 CEG48076.1 - 4.4e-07 30.0 11.0 9.2e-07 28.9 11.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arb2 PF09757.9 CEG48076.1 - 4.5e-05 22.7 0.0 7.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Kinase-like PF14531.6 CEG48076.1 - 0.0067 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG48076.1 - 0.0094 14.8 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEG48076.1 - 0.022 13.7 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DSPc PF00782.20 CEG48077.1 - 9.5e-30 103.1 0.3 1.4e-29 102.6 0.3 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CEG48077.1 - 0.00027 21.2 0.7 0.0039 17.5 0.1 2.6 1 1 1 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase2 PF03162.13 CEG48077.1 - 0.0024 17.5 0.2 0.0032 17.1 0.2 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CEG48077.1 - 0.0031 17.6 0.1 0.007 16.5 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CEG48077.1 - 0.0051 16.4 0.1 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CEG48077.1 - 0.045 13.4 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF1682 PF07946.14 CEG48079.1 - 0.12 11.6 4.4 0.13 11.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pet20 PF08692.10 CEG48079.1 - 3.2 8.5 5.2 6.1 7.6 4.0 1.8 1 1 1 2 2 2 0 Mitochondrial protein Pet20 DUF3122 PF11320.8 CEG48080.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) GTP_EFTU PF00009.27 CEG48084.1 - 3.5e-22 78.9 0.3 5.2e-22 78.3 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG48084.1 - 0.013 15.5 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NMT PF01233.19 CEG48085.1 - 3.5e-73 244.7 0.0 6.4e-73 243.9 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CEG48085.1 - 5e-73 245.1 0.0 1.1e-72 244.0 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 CEG48085.1 - 3.6e-06 27.1 0.1 0.00028 21.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain NMT_C PF02799.15 CEG48086.1 - 5.2e-81 271.2 0.1 9.6e-81 270.3 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CEG48086.1 - 2.1e-77 258.5 0.3 1.7e-76 255.5 0.1 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CEG48086.1 - 0.0012 19.0 0.2 0.0042 17.2 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG48086.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-rbx1 PF12678.7 CEG48087.1 - 5.1e-11 42.7 6.9 5.1e-11 42.7 6.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG48087.1 - 9.8e-11 41.8 7.0 9.8e-11 41.8 7.0 2.7 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 CEG48087.1 - 3e-07 30.4 0.9 3e-07 30.4 0.9 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEG48087.1 - 6.5e-06 26.1 2.4 6.5e-06 26.1 2.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEG48087.1 - 9.6e-06 25.4 6.7 9.6e-06 25.4 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG48087.1 - 6e-05 22.7 11.2 0.00025 20.7 8.0 3.2 2 1 0 2 2 2 1 RING-like zinc finger PX PF00787.24 CEG48087.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 CEG48087.1 - 0.00016 21.5 4.9 0.00016 21.5 4.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG48087.1 - 0.00042 20.1 4.8 0.00042 20.1 4.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG48087.1 - 0.0023 17.7 14.7 0.0031 17.3 10.0 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG48087.1 - 0.0039 17.0 4.0 0.0039 17.0 4.0 2.3 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CEG48087.1 - 0.045 13.8 0.9 0.045 13.8 0.9 2.8 3 0 0 3 3 2 0 Zinc-finger zf-Nse PF11789.8 CEG48087.1 - 0.22 11.4 3.9 0.76 9.6 2.9 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CEG48087.1 - 3.9 7.7 13.1 0.99 9.6 6.7 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain NTP_transferase PF00483.23 CEG48088.1 - 3.8e-20 72.5 0.0 6.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CEG48088.1 - 9e-11 42.4 0.0 1.5e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Mid1 PF12929.7 CEG48089.1 - 1.6e-16 60.5 11.3 2e-16 60.2 11.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CEG48089.1 - 0.025 15.2 9.4 0.79 10.4 0.8 2.5 1 1 1 2 2 2 0 Fz domain HGTP_anticodon PF03129.20 CEG48090.1 - 1.8e-18 66.4 0.0 3.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CEG48090.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zinc_ribbon_4 PF13717.6 CEG48090.1 - 0.026 14.4 0.8 9.7 6.2 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain HNH PF01844.23 CEG48090.1 - 0.2 11.9 2.6 18 5.6 0.5 2.8 2 0 0 2 2 2 0 HNH endonuclease Capsid_NCLDV PF04451.12 CEG48091.1 - 0.0021 17.9 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Large eukaryotic DNA virus major capsid protein Pet191_N PF10203.9 CEG48092.1 - 9.5e-23 80.3 6.6 1.1e-22 80.1 6.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 CEG48092.1 - 0.1 13.1 5.4 0.13 12.7 5.4 1.2 1 0 0 1 1 1 0 GCK domain CHCH PF06747.13 CEG48092.1 - 0.98 9.6 10.1 0.71 10.1 1.6 2.5 2 1 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 CEG48092.1 - 1.2 9.2 10.7 2.7 8.1 1.6 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like CotH PF08757.11 CEG48093.1 - 1.2e-28 100.6 2.7 3e-27 96.0 1.9 2.9 3 1 0 3 3 3 1 CotH kinase protein RIFIN PF02009.16 CEG48093.1 - 0.097 12.5 0.1 0.43 10.4 0.1 1.7 1 1 1 2 2 2 0 Rifin Ring_hydroxyl_B PF00866.18 CEG48096.1 - 0.0074 16.4 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 Ring hydroxylating beta subunit WD40 PF00400.32 CEG48097.1 - 9.6e-19 67.4 7.6 2.6e-07 31.2 0.1 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48097.1 - 2e-09 37.6 0.6 0.00033 20.9 0.2 4.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TelA PF05816.11 CEG48097.1 - 0.092 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) YfiO PF13525.6 CEG48097.1 - 0.12 12.1 0.3 1 9.1 0.1 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_19 PF14559.6 CEG48097.1 - 0.24 11.9 1.9 0.35 11.4 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 CEG48098.1 - 4.2e-29 101.6 0.0 5.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG48098.1 - 1.7e-22 80.1 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.8 CEG48098.1 - 0.0032 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kdo PF06293.14 CEG48098.1 - 0.04 13.3 0.0 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.18 CEG48099.1 - 1.9e-79 267.3 32.8 2.4e-79 267.0 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PPTA PF01239.22 CEG48099.1 - 0.084 12.6 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat SAE2 PF08573.10 CEG48100.1 - 0.075 14.2 5.7 0.1 13.7 5.7 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2570 PF10828.8 CEG48100.1 - 0.14 12.0 8.5 0.19 11.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) BPL_N PF09825.9 CEG48100.1 - 2.1 7.4 5.9 2.2 7.3 5.9 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal G_path_suppress PF15991.5 CEG48100.1 - 3.8 7.6 15.6 10 6.2 15.4 1.7 1 1 0 1 1 1 0 G-protein pathway suppressor Synaptobrevin PF00957.21 CEG48101.1 - 1.8e-15 56.5 0.7 3e-15 55.8 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEG48101.1 - 2.6e-12 46.6 0.0 4.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.13 CEG48101.1 - 0.015 15.1 0.9 0.04 13.7 0.4 2.0 2 1 1 3 3 3 0 Nsp1-like C-terminal region Herpes_teg_N PF04843.12 CEG48101.1 - 0.068 12.8 0.1 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DUF948 PF06103.11 CEG48101.1 - 0.27 11.5 1.2 0.54 10.5 1.2 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 CEG48102.1 - 6.3e-06 25.8 0.6 2.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Halogen_Hydrol PF10112.9 CEG48102.1 - 0.35 10.9 6.0 0.49 10.4 6.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ax_dynein_light PF10211.9 CEG48102.1 - 0.52 10.2 14.3 0.75 9.7 14.3 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Presenilin PF01080.17 CEG48102.1 - 0.59 8.8 1.3 0.67 8.7 1.3 1.0 1 0 0 1 1 1 0 Presenilin DUF3450 PF11932.8 CEG48102.1 - 1.6 7.9 10.9 2.1 7.6 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 CEG48102.1 - 3.7 6.0 6.3 4.4 5.8 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DNA_repr_REX1B PF14966.6 CEG48103.1 - 0.17 12.6 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA repair REX1-B Pkinase_C PF00433.24 CEG48103.1 - 2 9.2 5.8 4.4 8.1 2.3 2.9 2 1 0 2 2 2 0 Protein kinase C terminal domain PLAC8 PF04749.17 CEG48104.1 - 5.4e-17 62.6 10.7 1.1e-16 61.6 10.7 1.5 1 1 0 1 1 1 1 PLAC8 family DUF3671 PF12420.8 CEG48104.1 - 0.1 12.7 0.3 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function FixS PF03597.15 CEG48104.1 - 1.2 8.9 3.4 20 5.0 0.8 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Lipase_GDSL_2 PF13472.6 CEG48105.1 - 1.8e-09 38.2 0.0 2.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Armet PF10208.9 CEG48105.1 - 0.047 13.6 1.2 1.5 8.7 0.1 2.1 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding FoP_duplication PF13865.6 CEG48106.1 - 2.3e-17 63.3 13.5 2.3e-17 63.3 13.5 2.8 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Glyco_transf_41 PF13844.6 CEG48106.1 - 0.029 12.8 1.2 0.037 12.5 1.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 TPR_1 PF00515.28 CEG48107.1 - 6.6e-27 92.2 10.4 3.1e-07 29.9 0.0 10.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 CEG48107.1 - 1.6e-25 87.2 6.4 0.0059 16.7 0.0 9.6 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 CEG48107.1 - 8.4e-25 84.8 19.1 0.00047 20.1 0.0 10.7 10 1 1 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG48107.1 - 4e-24 84.6 25.7 4.6e-16 58.8 1.9 5.2 5 0 0 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEG48107.1 - 2.7e-20 72.6 20.7 4.5e-05 23.9 1.4 7.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEG48107.1 - 5.4e-18 65.1 21.0 0.0098 16.2 2.6 8.2 5 3 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 CEG48107.1 - 1.3e-14 53.7 17.5 0.58 11.1 0.1 9.3 5 4 5 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48107.1 - 3e-14 52.4 3.1 0.0066 16.1 0.0 7.6 5 1 3 8 8 7 3 TPR repeat TPR_16 PF13432.6 CEG48107.1 - 5.6e-14 52.5 16.5 0.15 12.7 0.7 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 CEG48107.1 - 3.1e-09 36.6 16.2 0.48 10.9 0.1 8.8 9 2 1 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG48107.1 - 4.1e-09 35.8 17.7 0.0029 17.5 0.0 8.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG48107.1 - 8.1e-09 35.6 19.3 0.55 11.0 0.4 8.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEG48107.1 - 0.0022 18.1 10.8 0.074 13.2 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEG48107.1 - 0.0026 17.7 1.8 0.047 13.7 0.0 3.2 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_20 PF14561.6 CEG48107.1 - 0.0068 16.7 5.6 0.037 14.4 0.4 3.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEG48107.1 - 0.0078 15.5 6.5 0.87 8.7 0.0 4.0 3 1 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 CEG48107.1 - 0.028 13.4 2.6 0.9 8.5 0.1 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 CEG48107.1 - 0.057 13.1 0.1 0.67 9.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Apo-CIII PF05778.12 CEG48107.1 - 0.073 12.7 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) TPR_10 PF13374.6 CEG48107.1 - 0.26 11.2 11.5 84 3.2 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 CEG48107.1 - 0.33 11.7 17.8 17 6.4 0.1 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 CEG48108.1 - 2.1e-08 34.6 0.0 3.6e-05 24.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG48108.1 - 1.3e-05 25.6 0.2 0.12 13.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG48108.1 - 2.2e-05 24.5 0.3 0.02 15.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CEG48108.1 - 4.3e-05 23.7 0.3 0.0069 16.7 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CEG48108.1 - 9.7e-05 22.6 0.7 0.23 12.0 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Neuro_bHLH PF12533.8 CEG48108.1 - 0.072 14.3 0.0 0.25 12.5 0.0 1.8 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor Ank_4 PF13637.6 CEG48109.1 - 9.9e-15 54.7 0.5 3.8e-12 46.5 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48109.1 - 1.1e-14 54.7 2.0 7.2e-11 42.5 0.2 3.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEG48109.1 - 2.1e-14 53.4 1.0 7.1e-11 42.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG48109.1 - 1.8e-13 49.3 1.8 1.1e-05 25.4 0.2 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CEG48109.1 - 1.5e-12 47.3 3.6 8.8e-08 32.3 0.8 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ion_trans PF00520.31 CEG48109.1 - 2.5e-12 46.6 25.0 3.4e-12 46.1 20.5 2.3 1 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 CEG48109.1 - 1.4e-06 27.3 17.8 6.7e-06 25.0 17.8 1.9 1 1 0 1 1 1 1 Polycystin cation channel Helicase_C_2 PF13307.6 CEG48110.1 - 1.1e-57 194.9 0.0 2.9e-57 193.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CEG48110.1 - 1.7e-51 174.3 2.1 1.7e-51 174.3 2.1 1.9 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CEG48110.1 - 0.0066 16.5 0.1 4.9 7.1 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Beta-Casp PF10996.8 CEG48111.1 - 2.7e-08 34.1 0.0 1.7e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CEG48111.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain tRNA-synt_2b PF00587.25 CEG48112.1 - 2.4e-28 99.3 0.0 4.2e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEG48112.1 - 5.6e-10 39.2 0.1 1.4e-08 34.8 0.0 2.9 3 0 0 3 3 3 1 Anticodon binding domain RasGEF PF00617.19 CEG48113.1 - 1.1e-26 94.1 0.5 3.1e-26 92.6 0.5 1.9 1 0 0 1 1 1 1 RasGEF domain Ank_5 PF13857.6 CEG48113.1 - 3.3e-23 81.4 1.4 4.3e-08 33.3 0.2 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG48113.1 - 3.8e-21 75.2 8.2 4.5e-06 27.1 0.0 7.4 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48113.1 - 3.9e-21 75.4 0.1 7.1e-09 36.1 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG48113.1 - 4e-20 69.8 3.7 0.0012 19.2 0.2 6.8 6 0 0 6 6 5 4 Ankyrin repeat Ank PF00023.30 CEG48113.1 - 2.5e-18 65.6 4.1 9.1e-05 22.7 0.7 6.1 5 0 0 5 5 5 3 Ankyrin repeat PH PF00169.29 CEG48113.1 - 3.3e-13 50.0 0.4 1.1e-12 48.3 0.4 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG48113.1 - 8e-06 26.1 0.5 3e-05 24.2 0.5 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CEG48113.1 - 0.00024 21.5 1.3 0.0012 19.2 1.3 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain VPS9 PF02204.18 CEG48113.1 - 0.028 14.6 0.2 0.63 10.3 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 CEG48113.1 - 0.035 14.4 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF702 PF05142.12 CEG48113.1 - 0.078 13.5 1.3 0.17 12.4 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) INCENP_ARK-bind PF03941.15 CEG48115.1 - 0.032 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region YndJ PF14158.6 CEG48115.1 - 0.047 13.0 0.1 0.047 13.0 0.1 1.0 1 0 0 1 1 1 0 YndJ-like protein KIX_2 PF16987.5 CEG48119.1 - 1.2e-09 38.0 0.2 1.2e-09 38.0 0.2 5.3 5 1 0 5 5 5 1 KIX domain FlxA PF14282.6 CEG48119.1 - 0.04 13.9 0.3 0.04 13.9 0.3 8.2 5 3 4 9 9 9 0 FlxA-like protein Sds3 PF08598.11 CEG48120.1 - 3.4e-06 27.2 7.1 4.6e-06 26.8 6.7 1.4 1 1 0 1 1 1 1 Sds3-like DUF1857 PF08982.11 CEG48120.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) DUF745 PF05335.13 CEG48120.1 - 5.6 6.7 6.0 0.97 9.1 0.5 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF745) Complex1_LYR_2 PF13233.6 CEG48121.1 - 0.023 15.4 0.8 0.023 15.4 0.8 2.0 2 0 0 2 2 2 0 Complex1_LYR-like RNA_pol_L PF01193.24 CEG48123.1 - 0.12 11.8 0.0 0.52 9.8 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Elicitin PF00964.17 CEG48128.1 - 1.5e-18 66.6 0.1 2.6e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Elicitin CtIP_N PF10482.9 CEG48128.1 - 0.035 14.2 0.2 0.054 13.5 0.2 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain AAA_6 PF12774.7 CEG48129.1 - 4.4e-126 420.3 0.4 1.1e-124 415.6 0.0 3.5 4 1 0 4 4 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CEG48129.1 - 5.3e-114 381.4 9.3 5.3e-114 381.4 9.3 3.6 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CEG48129.1 - 1.6e-99 334.1 1.1 1.6e-99 334.1 1.1 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CEG48129.1 - 1.6e-73 246.5 0.1 1.6e-73 246.5 0.1 4.6 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 CEG48129.1 - 2.2e-66 223.8 0.0 3e-65 220.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CEG48129.1 - 1.5e-41 141.9 0.0 1e-33 116.4 0.0 5.1 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 CEG48129.1 - 8e-40 137.0 0.0 3.1e-39 135.0 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CEG48129.1 - 2e-34 118.8 0.0 5.7e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CEG48129.1 - 6.2e-34 117.5 9.9 1.7e-33 116.1 9.9 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CEG48129.1 - 5.7e-30 103.8 0.0 7.5e-29 100.2 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CEG48129.1 - 1.6e-27 96.2 0.0 5.7e-11 42.6 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEG48129.1 - 2.1e-21 76.4 0.2 3.8e-20 72.3 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CEG48129.1 - 2.1e-13 50.8 0.0 0.011 16.1 0.0 5.4 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEG48129.1 - 9.5e-12 45.4 0.0 0.0097 16.2 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 CEG48129.1 - 8.8e-10 39.2 0.2 2.5 8.5 0.0 6.8 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 CEG48129.1 - 3.9e-07 30.7 0.1 2.2 8.8 0.0 5.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CEG48129.1 - 9.6e-05 21.8 0.4 3.8 6.8 0.0 4.3 4 0 0 4 4 4 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CEG48129.1 - 0.0001 22.2 0.0 6.9 6.5 0.0 3.9 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 CEG48129.1 - 0.00013 22.2 5.6 2.1 8.5 0.0 5.5 6 0 0 6 6 4 1 AAA domain AAA_30 PF13604.6 CEG48129.1 - 0.00024 20.9 0.4 14 5.3 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 CEG48129.1 - 0.00036 20.9 1.2 0.11 12.8 0.0 4.8 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 CEG48129.1 - 0.00084 18.8 3.6 0.49 9.7 0.0 4.4 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CEG48129.1 - 0.0011 18.1 0.0 0.34 9.9 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 CEG48129.1 - 0.0012 19.0 0.0 0.034 14.4 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain RNA_helicase PF00910.22 CEG48129.1 - 0.0014 19.0 0.1 4.6 7.7 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 CEG48129.1 - 0.0021 17.8 0.8 48 3.6 0.0 5.7 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 CEG48129.1 - 0.0028 18.2 8.8 5 7.6 0.0 6.1 7 0 0 7 7 4 0 ABC transporter AAA_25 PF13481.6 CEG48129.1 - 0.003 17.2 0.5 0.36 10.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_lid_7 PF17867.1 CEG48129.1 - 0.0051 17.0 0.3 0.12 12.6 0.0 3.2 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_29 PF13555.6 CEG48129.1 - 0.0051 16.5 0.1 6.8 6.5 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CEG48129.1 - 0.007 16.1 0.0 7.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain RuvB_N PF05496.12 CEG48129.1 - 0.0073 16.1 0.1 0.34 10.6 0.0 3.1 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CEG48129.1 - 0.016 14.9 2.4 1 9.0 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.12 CEG48129.1 - 0.047 13.6 0.2 21 5.0 0.0 4.1 3 0 0 3 3 3 0 NACHT domain Sigma54_activ_2 PF14532.6 CEG48129.1 - 0.071 13.2 0.2 16 5.6 0.0 4.2 4 0 0 4 4 3 0 Sigma-54 interaction domain Rad17 PF03215.15 CEG48129.1 - 0.092 12.7 0.2 29 4.5 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain TsaE PF02367.17 CEG48129.1 - 0.15 12.0 1.6 9.4 6.3 0.0 3.8 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4527 PF15030.6 CEG48129.1 - 0.38 10.2 14.4 5.4 6.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4527) eIF3_subunit PF08597.10 CEG48129.1 - 0.45 10.4 10.3 1.3 8.8 10.3 1.8 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GAT PF03127.14 CEG48129.1 - 0.63 10.4 5.9 6.9 7.1 0.1 4.5 3 0 0 3 3 3 0 GAT domain Histone PF00125.24 CEG48130.1 - 1.3e-19 70.8 0.0 1.8e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CEG48130.1 - 3.5e-13 49.0 0.3 6.3e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CEG48130.1 - 0.0003 21.0 0.0 0.00042 20.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Retrotrans_gag PF03732.17 CEG48131.1 - 3.9e-13 49.5 0.0 5.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein WD40 PF00400.32 CEG48132.1 - 0.00015 22.4 0.5 0.0004 21.1 0.5 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48132.1 - 0.014 15.7 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Gam PF06064.11 CEG48134.1 - 0.0028 17.8 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 Host-nuclease inhibitor protein Gam B2-adapt-app_C PF09066.10 CEG48135.1 - 4.8e-14 52.4 3.6 7.3e-14 51.8 0.8 2.5 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Shisa PF13908.6 CEG48135.1 - 0.073 13.3 0.1 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Nop53 PF07767.11 CEG48136.1 - 5.1e-37 128.2 37.5 7.3e-37 127.7 37.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3573 PF12097.8 CEG48136.1 - 0.11 11.4 2.7 0.19 10.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GAS PF13851.6 CEG48137.1 - 0.31 10.4 14.3 0.31 10.4 4.2 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Med22 PF06179.12 CEG48137.1 - 0.34 11.2 5.6 0.74 10.1 5.1 1.9 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex MRP-L28 PF09812.9 CEG48137.1 - 0.43 10.7 11.5 10 6.2 1.6 3.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L28 Exonuc_VII_S PF02609.16 CEG48137.1 - 0.62 10.2 4.8 1 9.5 1.1 3.0 3 0 0 3 3 3 0 Exonuclease VII small subunit CorA PF01544.18 CEG48137.1 - 1.2 8.4 5.6 5.3 6.3 5.6 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 CEG48137.1 - 1.3 9.4 5.1 3.3 8.0 0.3 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ApoL PF05461.11 CEG48137.1 - 2.6 7.3 17.7 2.5 7.3 14.0 2.4 1 1 1 2 2 2 0 Apolipoprotein L Exonuc_VII_L PF02601.15 CEG48137.1 - 2.8 7.4 9.8 0.96 9.0 7.1 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 CEG48137.1 - 5 7.5 10.0 7.3 7.0 0.2 3.9 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PMEI PF04043.15 CEG48137.1 - 7.7 6.8 8.2 28 5.0 0.7 3.2 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor IZUMO PF15005.6 CEG48137.1 - 9.9 6.7 9.2 1.9 9.0 4.9 2.0 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Patatin PF01734.22 CEG48139.1 - 1.4e-12 48.2 0.2 1.7e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 Patatin-like phospholipase Pkinase PF00069.25 CEG48140.1 - 1.6e-61 208.0 0.0 1.2e-60 205.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48140.1 - 8e-36 123.6 0.0 1e-33 116.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 CEG48140.1 - 6e-06 25.9 0.1 9.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 CEG48140.1 - 9.7e-06 24.8 0.2 1.4e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEG48140.1 - 4e-05 23.3 0.4 6.7e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CEG48140.1 - 0.00019 20.9 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CEG48140.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG48140.1 - 0.012 15.5 0.1 0.038 13.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG48140.1 - 0.091 11.5 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FtsJ PF01728.19 CEG48141.1 - 3.3e-67 226.0 0.5 5.3e-67 225.4 0.2 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CEG48141.1 - 0.00024 20.8 0.0 0.00059 19.5 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F zf-RING_2 PF13639.6 CEG48142.1 - 2.4e-14 53.4 6.5 3.9e-14 52.7 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain Kelch_4 PF13418.6 CEG48142.1 - 4.6e-11 42.6 4.5 0.00097 19.1 0.1 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG48142.1 - 1.5e-10 40.8 6.3 0.00038 20.4 0.2 3.6 3 0 0 3 3 3 3 Kelch motif zf-C3HC4_2 PF13923.6 CEG48142.1 - 1.3e-09 37.7 5.9 2.3e-09 37.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG48142.1 - 2.2e-09 36.9 3.9 4.2e-09 36.0 3.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CEG48142.1 - 7.8e-09 35.7 8.7 3e-08 33.8 8.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG48142.1 - 6.2e-08 32.4 5.4 1e-07 31.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_3 PF13415.6 CEG48142.1 - 1.1e-06 28.8 4.5 0.13 12.6 0.3 3.7 4 0 0 4 4 3 2 Galactose oxidase, central domain zf-RING_5 PF14634.6 CEG48142.1 - 3.1e-06 27.0 7.0 5.1e-06 26.4 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG48142.1 - 1.5e-05 24.9 3.8 2.8e-05 24.0 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CEG48142.1 - 2.1e-05 24.5 5.4 7.3e-05 22.8 5.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CEG48142.1 - 6.3e-05 22.8 6.2 0.00011 22.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.25 CEG48142.1 - 0.00025 20.6 5.4 0.17 11.5 0.2 3.6 3 0 0 3 3 3 1 Kelch motif Zn_ribbon_17 PF17120.5 CEG48142.1 - 0.00069 19.2 4.4 0.0013 18.3 4.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEG48142.1 - 0.0012 18.6 9.5 0.008 16.0 9.9 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Kelch_6 PF13964.6 CEG48142.1 - 0.002 18.4 8.4 1.2 9.6 0.2 3.4 2 1 1 3 3 3 2 Kelch motif zf-Nse PF11789.8 CEG48142.1 - 0.01 15.7 5.0 0.018 14.8 5.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CEG48142.1 - 0.019 15.1 4.9 0.041 14.0 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CEG48142.1 - 0.024 14.8 6.4 0.1 12.8 6.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 CEG48142.1 - 0.031 14.5 2.2 0.031 14.5 2.2 1.6 2 0 0 2 2 1 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 CEG48142.1 - 0.045 13.8 5.9 0.085 12.9 2.1 2.4 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 CEG48142.1 - 0.065 13.4 3.4 0.17 12.1 3.4 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CEG48142.1 - 0.066 13.5 1.4 0.14 12.4 1.4 1.5 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.14 CEG48142.1 - 0.28 11.1 2.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif PH PF00169.29 CEG48143.1 - 0.089 13.3 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 PH domain Thiolase_N PF00108.23 CEG48144.1 - 3.3e-68 229.9 0.1 9.9e-68 228.3 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEG48144.1 - 2.3e-36 124.1 0.0 4.9e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain SpoVAD PF07451.11 CEG48144.1 - 2.1e-06 26.7 0.0 1.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 CEG48144.1 - 6.5e-05 22.6 5.5 8.6e-05 22.2 2.0 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain C-C_Bond_Lyase PF15617.6 CEG48144.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold ACP_syn_III PF08545.10 CEG48144.1 - 0.046 13.6 0.4 1.9 8.4 0.2 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FYVE PF01363.21 CEG48145.1 - 0.0057 16.8 12.5 0.011 15.8 12.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 CEG48145.1 - 0.099 12.7 7.2 0.35 10.9 7.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 CEG48145.1 - 0.43 10.9 8.0 1.4 9.3 5.1 2.4 2 0 0 2 2 2 0 C1 domain BT1 PF03092.16 CEG48146.1 - 5.9e-16 57.8 18.2 6.4e-11 41.2 0.8 3.4 2 1 1 3 3 3 3 BT1 family UAA PF08449.11 CEG48147.1 - 4.7e-29 101.6 6.0 6.5e-29 101.1 6.0 1.1 1 0 0 1 1 1 1 UAA transporter family DNA_binding_1 PF01035.20 CEG48147.1 - 6e-26 90.4 0.1 2.6e-25 88.3 0.0 2.2 3 0 0 3 3 3 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_L9_N PF01281.19 CEG48147.1 - 7e-19 67.1 1.1 1e-18 66.6 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 CEG48147.1 - 2e-10 41.0 1.2 4e-10 40.0 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Nuc_sug_transp PF04142.15 CEG48147.1 - 0.00017 20.9 0.2 0.00026 20.3 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 CEG48147.1 - 0.0015 17.6 4.7 0.0023 17.0 4.7 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like PIRT PF15099.6 CEG48147.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family VKOR PF07884.14 CEG48147.1 - 9.3 6.5 9.0 1.6 8.9 5.0 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family BT1 PF03092.16 CEG48148.1 - 6.5e-17 61.0 8.4 2.7e-10 39.1 0.1 3.3 3 0 0 3 3 3 3 BT1 family PseudoU_synth_2 PF00849.22 CEG48148.1 - 6.8e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CEG48148.1 - 1.5e-09 37.4 0.1 3.8e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 S4 domain Arm PF00514.23 CEG48149.1 - 2.7e-32 109.8 16.2 8.1e-09 35.2 0.0 9.1 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CEG48149.1 - 4.9e-18 63.7 7.1 0.064 13.5 0.1 8.2 8 0 0 8 8 7 4 HEAT repeat HEAT_2 PF13646.6 CEG48149.1 - 4.7e-14 52.5 10.5 0.00045 20.5 0.4 5.7 2 2 6 8 8 8 7 HEAT repeats Cnd1 PF12717.7 CEG48149.1 - 4.4e-13 49.6 0.8 0.0039 17.2 0.0 4.5 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEG48149.1 - 3.4e-12 46.6 18.1 0.00091 19.7 0.3 7.1 6 2 2 8 8 8 6 HEAT-like repeat Adaptin_N PF01602.20 CEG48149.1 - 3.9e-08 32.3 3.1 0.002 16.8 0.0 3.5 2 2 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 CEG48149.1 - 7e-07 29.2 0.0 0.81 9.4 0.0 4.1 2 1 2 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 CEG48149.1 - 3.6e-06 26.7 2.5 0.015 14.9 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal CHASE6_C PF17150.4 CEG48149.1 - 5.3e-06 27.0 0.4 35 5.2 0.0 6.0 5 1 1 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 CEG48149.1 - 0.00023 19.8 3.9 0.0016 17.0 0.1 3.2 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 CEG48149.1 - 0.00035 20.7 0.0 3.8 7.8 0.0 4.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 CEG48149.1 - 0.00038 20.6 0.1 7.4 6.7 0.0 4.3 3 2 2 5 5 5 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 CEG48149.1 - 0.00085 19.3 1.6 5 7.2 0.1 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT_UF PF18817.1 CEG48149.1 - 0.0055 16.9 0.3 0.46 10.8 0.1 3.7 4 0 0 4 4 4 1 Repeat of uncharacterized protein PH0542 Arm_2 PF04826.13 CEG48149.1 - 0.015 14.8 1.6 15 4.9 0.0 4.2 3 1 1 5 5 5 0 Armadillo-like U3snoRNP10 PF12397.8 CEG48149.1 - 0.096 13.0 2.3 4.4 7.7 0.1 3.2 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 HEAT_PBS PF03130.16 CEG48149.1 - 5.2 8.0 15.1 31 5.6 0.1 5.6 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat PDCD2_C PF04194.13 CEG48150.1 - 2.8e-32 112.2 6.4 3.1e-32 112.0 0.0 2.9 2 2 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain WRNPLPNID PF15017.6 CEG48150.1 - 0.23 12.4 0.1 0.23 12.4 0.1 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Zn-ribbon_8 PF09723.10 CEG48150.1 - 1 9.5 5.9 31 4.8 0.2 3.7 3 0 0 3 3 3 0 Zinc ribbon domain DUF543 PF04418.12 CEG48151.1 - 1.5e-19 69.7 0.4 1.8e-19 69.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) FHA PF00498.26 CEG48152.1 - 5e-09 36.4 0.0 1.5e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 FHA domain RapA_C PF12137.8 CEG48152.1 - 0.024 13.7 1.0 0.032 13.3 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal YEATS PF03366.16 CEG48153.1 - 4.1e-28 97.2 0.0 6.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 YEATS family DUF3231 PF11553.8 CEG48153.1 - 0.06 13.0 0.2 0.099 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) DUF3967 PF13152.6 CEG48153.1 - 1.8 8.4 5.3 13 5.6 4.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3967) SNRNP27 PF08648.12 CEG48154.1 - 3.7e-27 94.1 1.0 5.2e-27 93.7 1.0 1.2 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Fungus-induced PF10917.8 CEG48155.1 - 0.091 13.1 0.4 0.21 11.9 0.4 1.6 1 0 0 1 1 1 0 Fungus-induced protein DUF5352 PF17303.2 CEG48156.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5352) TRAP-delta PF05404.12 CEG48158.1 - 0.02 14.4 0.2 0.075 12.6 0.0 1.9 2 1 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) ubiquitin PF00240.23 CEG48158.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF448 PF04296.13 CEG48158.1 - 0.19 11.6 0.2 0.86 9.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF448) Dimer_Tnp_hAT PF05699.14 CEG48167.1 - 1.4e-08 34.4 0.1 4.6e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_2 PF07727.14 CEG48168.1 - 3.3e-26 92.4 0.0 4.4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 CEG48172.1 - 7.3e-39 131.1 24.8 6.9e-08 33.0 0.2 9.0 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48172.1 - 5.3e-11 42.7 0.5 0.29 11.5 0.0 6.9 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG48172.1 - 5.6e-05 22.0 2.5 0.38 9.3 0.0 5.0 3 1 2 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CEG48172.1 - 0.004 16.5 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain LisH PF08513.11 CEG48172.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 LisH Arcadin_1 PF18653.1 CEG48172.1 - 0.2 11.7 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Arcadin 1 Asparaginase_2 PF01112.18 CEG48174.1 - 4.3e-21 75.2 0.1 1.1e-17 64.0 0.0 3.0 2 1 0 2 2 2 2 Asparaginase Lipase_GDSL_2 PF13472.6 CEG48175.1 - 1.1e-22 81.3 0.0 1.3e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEG48175.1 - 1.4e-17 64.4 0.0 9.8e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase cNMP_binding PF00027.29 CEG48176.1 - 1e-40 137.7 3.2 1.2e-15 57.4 0.1 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain UPF0128 PF03673.13 CEG48176.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) BDHCT_assoc PF16204.5 CEG48176.1 - 1.2 8.8 9.9 0.088 12.5 3.8 2.4 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein Jas PF16135.5 CEG48177.1 - 8.3e-12 45.1 1.6 2.5e-05 24.3 0.0 3.3 2 0 0 2 2 2 2 TPL-binding domain in jasmonate signalling zf-C2HC_2 PF13913.6 CEG48177.1 - 0.4 10.6 16.1 1.8 8.6 0.1 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type c-SKI_SMAD_bind PF08782.10 CEG48177.1 - 4 7.7 17.4 0.25 11.6 0.8 3.9 4 0 0 4 4 4 0 c-SKI Smad4 binding domain WD40 PF00400.32 CEG48180.1 - 3.9e-25 87.6 15.9 3.6e-06 27.6 0.4 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48180.1 - 8.1e-08 32.5 1.3 0.017 15.4 0.0 5.0 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 CEG48180.1 - 5.2e-05 23.6 24.1 0.00031 21.0 22.8 2.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PQQ_3 PF13570.6 CEG48180.1 - 0.0059 17.1 0.0 1.8 9.2 0.0 3.5 3 1 0 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 CEG48180.1 - 0.012 14.6 0.4 1.2 8.0 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD-SLDH PF12318.8 CEG48180.1 - 0.044 13.9 3.3 0.11 12.5 2.8 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Fe-S_biosyn PF01521.20 CEG48181.1 - 1.5e-15 57.3 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Med25_SD1 PF11235.8 CEG48181.1 - 0.093 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 CMAS PF02353.20 CEG48185.1 - 1.5e-85 286.8 0.1 1.8e-85 286.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEG48185.1 - 4.2e-13 49.8 0.0 8.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG48185.1 - 9.2e-11 42.3 0.0 1.9e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG48185.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG48185.1 - 3.6e-10 39.9 0.0 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG48185.1 - 5.2e-08 33.5 0.0 1.3e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG48185.1 - 2.7e-05 23.8 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 CEG48185.1 - 0.00057 19.3 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 CEG48185.1 - 0.00088 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG48185.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CEG48185.1 - 0.005 16.5 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 CEG48185.1 - 0.054 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 CEG48185.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) GCD14 PF08704.10 CEG48185.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 CEG48185.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase adh_short_C2 PF13561.6 CEG48186.1 - 4.3e-50 170.5 1.4 5.4e-50 170.1 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG48186.1 - 1.2e-44 152.1 2.0 1.7e-44 151.7 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG48186.1 - 4e-09 36.7 0.1 8.6e-09 35.5 0.1 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEG48186.1 - 0.0011 18.9 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CEG48186.1 - 0.0018 18.8 0.5 0.0081 16.7 0.3 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CEG48186.1 - 0.0029 17.9 0.0 0.0048 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CEG48186.1 - 0.025 14.0 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Crp PF00325.20 CEG48186.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Shikimate_DH PF01488.20 CEG48186.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DASH_Dad4 PF08650.10 CEG48188.1 - 7.5e-17 61.1 0.1 8.4e-17 60.9 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 CEG48188.1 - 0.068 13.4 0.2 0.08 13.1 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 Helicase_C PF00271.31 CEG48189.1 - 6.5e-15 55.4 0.0 2e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.22 CEG48189.1 - 3.7e-10 39.7 0.0 9.6e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 CEG48189.1 - 4.9e-09 36.2 0.1 5.6e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_23 PF13476.6 CEG48189.1 - 0.024 15.2 0.0 0.065 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEG48189.1 - 0.057 13.5 0.2 1.4 9.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEG48189.1 - 0.084 13.1 0.3 0.64 10.3 0.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEG48189.1 - 0.095 13.1 0.3 1 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Inv-AAD PF18785.1 CEG48191.1 - 0.021 14.7 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase PPR_2 PF13041.6 CEG48191.1 - 0.11 12.7 0.0 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family Methyltransf_31 PF13847.6 CEG48192.1 - 5.9e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEG48192.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEG48192.1 - 1.8e-05 25.4 0.1 7.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CEG48192.1 - 2.8e-05 23.6 0.0 8.3e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG48192.1 - 0.0013 18.4 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 CEG48192.1 - 0.0085 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 CEG48192.1 - 0.021 15.5 0.1 0.085 13.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 CEG48192.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 CEG48192.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 CEG48192.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEG48192.1 - 0.15 12.8 0.1 1 10.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain rRNA_processing PF08524.11 CEG48192.1 - 0.51 10.4 6.5 0.92 9.5 6.5 1.4 1 0 0 1 1 1 0 rRNA processing FUSC PF04632.12 CEG48192.1 - 3 6.3 5.5 5.2 5.5 5.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-Tim10_DDP PF02953.15 CEG48193.1 - 1.4e-14 53.5 0.2 2.6e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TGase_elicitor PF16683.5 CEG48194.1 - 2.1e-22 79.4 0.1 2.7e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Transglutaminase elicitor RVT_2 PF07727.14 CEG48197.1 - 1.2e-13 51.3 0.0 2.9e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) BpuSI_N PF15516.6 CEG48197.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.4 1 1 0 1 1 1 0 BpuSI N-terminal domain Astro_capsid_p2 PF16580.5 CEG48198.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike Jacalin PF01419.17 CEG48200.1 - 3.5e-09 36.7 0.1 4.8e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain FH2 PF02181.23 CEG48202.1 - 1.5e-70 238.2 8.3 1.5e-70 238.2 8.3 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 CEG48202.1 - 3.4e-19 69.8 5.4 1.4e-08 35.3 1.7 3.0 2 1 0 2 2 2 2 Subunit CCDC53 of WASH complex Orai-1 PF07856.12 CEG48203.1 - 0.00095 18.9 0.2 0.002 17.8 0.1 1.5 1 1 0 1 1 1 1 Mediator of CRAC channel activity CytadhesinP1 PF12378.8 CEG48203.1 - 0.17 12.0 0.0 0.5 10.6 0.0 1.8 1 1 0 1 1 1 0 Trypsin-sensitive surface-exposed protein FYVE PF01363.21 CEG48204.1 - 0.0024 17.9 21.1 0.0053 16.9 21.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger RTP1_C2 PF10304.9 CEG48205.1 - 0.13 12.0 0.7 0.22 11.3 0.7 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Imm30 PF15565.6 CEG48207.1 - 0.17 11.9 3.8 55 3.9 0.1 4.2 4 0 0 4 4 4 0 Immunity protein 30 Raf1_HTH PF18579.1 CEG48207.1 - 0.18 11.5 5.9 19 5.1 0.0 4.5 5 0 0 5 5 5 0 Rubisco accumulation factor 1 helix turn helix domain DED PF01335.21 CEG48207.1 - 0.81 10.0 4.3 0.71 10.2 0.8 2.8 3 0 0 3 3 3 0 Death effector domain PYRIN PF02758.16 CEG48207.1 - 5.6 7.2 7.4 21 5.4 0.2 3.5 4 0 0 4 4 4 0 PAAD/DAPIN/Pyrin domain LRR_6 PF13516.6 CEG48210.1 - 0.033 14.3 0.0 12 6.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Y_phosphatase2 PF03162.13 CEG48211.1 - 1.5e-48 164.5 0.0 1.7e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEG48211.1 - 4e-07 30.3 0.0 8.8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Rad60-SLD PF11976.8 CEG48212.1 - 1.8e-17 62.9 0.0 2.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEG48212.1 - 6.7e-11 41.8 0.0 8.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family OCRL_clath_bd PF16726.5 CEG48212.1 - 0.073 13.3 0.1 1.7 8.8 0.0 2.0 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain CAMSAP_CC1 PF17095.5 CEG48212.1 - 0.13 12.1 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin LSM PF01423.22 CEG48213.1 - 1.8e-16 59.6 0.0 2.6e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEG48213.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Dpy-30 PF05186.13 CEG48214.1 - 7.6e-19 67.1 0.3 1e-18 66.7 0.3 1.2 1 0 0 1 1 1 1 Dpy-30 motif Pannexin_like PF12534.8 CEG48214.1 - 0.096 11.8 2.9 0.11 11.5 2.9 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4637 PF15470.6 CEG48214.1 - 0.57 9.9 6.3 0.74 9.5 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Zip PF02535.22 CEG48214.1 - 1.2 8.2 2.1 1.4 8.0 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CEG48214.1 - 1.4 7.6 4.5 1.5 7.5 4.5 1.1 1 0 0 1 1 1 0 Presenilin PMSI1 PF15322.6 CEG48214.1 - 2.7 7.4 6.2 3.1 7.1 6.2 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Tim54 PF11711.8 CEG48214.1 - 3.1 6.5 7.8 3.6 6.3 7.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ULD PF16534.5 CEG48215.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like oligomerisation domain of SATB Pkinase PF00069.25 CEG48216.1 - 1e-44 152.9 0.0 1.7e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48216.1 - 2.9e-40 138.2 0.0 4.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG48216.1 - 4.4e-07 29.6 11.3 0.0028 17.4 0.8 3.4 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CEG48216.1 - 7.5e-05 23.0 14.3 0.0076 16.6 1.3 4.6 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG48216.1 - 3.3 8.6 5.3 1.6e+02 3.5 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat TGase_elicitor PF16683.5 CEG48217.1 - 1.3e-116 389.3 0.3 1.6e-116 389.1 0.3 1.0 1 0 0 1 1 1 1 Transglutaminase elicitor Rad21_Rec8_N PF04825.13 CEG48218.1 - 4.9e-41 139.3 0.0 1.4e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CEG48218.1 - 1.3e-13 50.0 0.4 5.7e-13 47.9 0.4 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 CEG48218.1 - 0.025 14.8 0.0 0.085 13.1 0.0 1.9 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EF-hand_6 PF13405.6 CEG48219.1 - 1.5e-11 43.2 14.2 0.086 12.8 0.1 8.4 8 0 0 8 8 8 3 EF-hand domain EF-hand_7 PF13499.6 CEG48219.1 - 5.1e-10 39.7 13.8 0.74 10.3 0.0 7.7 7 1 1 8 8 8 5 EF-hand domain pair EF-hand_1 PF00036.32 CEG48219.1 - 2.1e-09 36.3 10.9 0.39 10.4 0.0 7.8 8 0 0 8 8 8 4 EF hand AGTRAP PF06396.11 CEG48219.1 - 0.0095 15.7 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Adenine_glyco PF03352.13 CEG48219.1 - 0.034 13.9 2.9 22 4.8 0.0 4.0 4 0 0 4 4 4 0 Methyladenine glycosylase DSPn PF14671.6 CEG48219.1 - 0.065 13.7 0.1 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Glyco_hydro_17 PF00332.18 CEG48219.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 RST PF12174.8 CEG48219.1 - 2.2 8.3 21.2 3.6 7.6 0.1 6.3 7 0 0 7 7 7 0 RCD1-SRO-TAF4 (RST) plant domain GTP_cyclohydroI PF01227.22 CEG48220.1 - 8.4e-77 256.6 0.9 1.1e-76 256.3 0.9 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CEG48220.1 - 0.0029 17.7 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF3730 PF12530.8 CEG48220.1 - 0.046 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) IMS PF00817.20 CEG48221.1 - 5.4e-36 123.9 0.1 1.3e-35 122.7 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CEG48221.1 - 5.4e-15 56.1 0.0 1.9e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 CEG48221.1 - 2e-12 47.3 0.0 5.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CEG48221.1 - 9.2e-10 38.8 0.0 2.4e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEG48221.1 - 6.2e-06 26.1 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 CEG48221.1 - 1.3e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 CEG48221.1 - 6.3e-05 23.1 0.0 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif UBM PF14377.6 CEG48221.1 - 0.0026 17.2 0.3 0.13 11.8 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin binding region DUF4332 PF14229.6 CEG48221.1 - 0.0036 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Cdd1 PF11731.8 CEG48221.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.6 CEG48221.1 - 0.16 12.6 0.0 16 6.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pkinase PF00069.25 CEG48222.1 - 1.7e-48 165.3 0.0 2.5e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48222.1 - 2.4e-43 148.3 0.0 3.3e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG48222.1 - 0.062 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MGC-24 PF05283.11 CEG48222.1 - 0.096 13.1 7.2 0.032 14.7 3.4 2.0 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_S3_C PF00189.20 CEG48223.1 - 3.3e-23 82.0 2.7 5.4e-23 81.3 2.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CEG48223.1 - 5.7e-12 45.3 0.0 9.4e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CEG48223.1 - 0.086 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TBP PF00352.21 CEG48223.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) nec1 PF10379.9 CEG48223.1 - 0.18 11.3 0.0 1.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Virulence protein nec1 FYVE PF01363.21 CEG48224.1 - 0.0028 17.7 11.4 0.0028 17.7 11.4 2.4 2 0 0 2 2 2 1 FYVE zinc finger PARP PF00644.20 CEG48225.1 - 2.3e-49 167.6 0.0 5.1e-49 166.5 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CEG48225.1 - 2.3e-42 144.3 0.4 4e-42 143.5 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CEG48225.1 - 4.6e-14 52.2 0.9 2.6e-13 49.8 0.3 2.5 1 1 1 2 2 2 1 WGR domain PARP PF00644.20 CEG48226.1 - 2.7e-57 193.5 0.2 2.4e-56 190.4 0.1 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CEG48226.1 - 5.9e-38 130.0 3.0 1.2e-37 129.1 3.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CEG48226.1 - 6.6e-17 61.3 0.6 1.5e-16 60.2 0.6 1.6 1 0 0 1 1 1 1 WGR domain zf-HC5HC2H PF13771.6 CEG48226.1 - 0.0082 16.4 0.4 0.022 15.0 0.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG48226.1 - 0.12 12.5 2.2 0.27 11.4 2.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain WD40 PF00400.32 CEG48227.1 - 1.2e-38 130.4 22.0 7.9e-10 39.2 0.5 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48227.1 - 6.3e-19 68.1 1.7 0.00016 21.9 0.0 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG48227.1 - 3.6e-10 40.0 0.9 0.026 14.4 0.0 3.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 CEG48227.1 - 8.7e-09 35.0 0.6 2e-08 33.9 0.6 1.7 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 CEG48227.1 - 0.008 15.5 0.0 0.38 10.0 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain CTP_transf_like PF01467.26 CEG48229.1 - 2.2e-37 128.4 0.2 5e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CEG48229.1 - 4.8e-05 23.3 0.6 0.36 10.7 0.1 3.2 2 1 0 2 2 2 2 FAD synthetase TPR_8 PF13181.6 CEG48229.1 - 0.00011 22.1 3.8 0.091 13.0 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48229.1 - 0.00014 21.4 0.5 0.00047 19.8 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 CEG48229.1 - 0.00016 21.8 0.0 0.063 13.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG48229.1 - 0.00097 19.1 6.6 2.9 8.2 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DivIC PF04977.15 CEG48229.1 - 0.01 15.6 0.4 0.029 14.1 0.4 1.8 1 0 0 1 1 1 0 Septum formation initiator TPR_1 PF00515.28 CEG48229.1 - 0.011 15.5 8.2 6.2 6.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2919 PF11143.8 CEG48229.1 - 0.035 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) TPR_12 PF13424.6 CEG48229.1 - 0.044 14.1 0.2 0.25 11.7 0.2 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.20 CEG48230.1 - 1e-23 83.3 0.1 2.5e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CEG48230.1 - 2.9e-21 75.2 0.2 6.8e-21 74.1 0.2 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CEG48230.1 - 4.9e-11 43.1 5.3 9.9e-11 42.1 5.3 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein TCR PF03638.15 CEG48231.1 - 2.7e-35 120.4 83.5 9.4e-12 45.0 23.1 3.6 3 0 0 3 3 3 3 Tesmin/TSO1-like CXC domain, cysteine-rich domain Hydrolase_6 PF13344.6 CEG48232.1 - 2.4e-26 91.8 0.0 7.3e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG48232.1 - 2.4e-19 69.1 0.0 6.1e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CEG48232.1 - 0.002 18.4 0.0 9.5 6.4 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEG48232.1 - 0.0029 17.7 0.1 0.051 13.7 0.0 2.8 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Glyco_transf_92 PF01697.27 CEG48232.1 - 0.062 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 MdoG PF04349.12 CEG48233.1 - 0.092 11.7 0.0 0.099 11.6 0.0 1.0 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Homeobox_KN PF05920.11 CEG48234.1 - 2.8e-23 81.5 8.3 4.4e-17 61.7 0.1 3.8 4 0 0 4 4 4 2 Homeobox KN domain Homeodomain PF00046.29 CEG48234.1 - 1.6e-09 37.5 0.9 4.9e-06 26.3 0.1 3.0 2 1 0 2 2 2 2 Homeodomain Homez PF11569.8 CEG48234.1 - 0.14 11.6 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez MUG113 PF13455.6 CEG48236.1 - 0.049 14.3 0.2 0.071 13.8 0.2 1.2 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 DNA_pol_B_palm PF14792.6 CEG48237.1 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CEG48237.1 - 0.028 14.6 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase beta thumb adh_short PF00106.25 CEG48238.1 - 1.7e-44 151.6 0.4 2e-44 151.4 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG48238.1 - 3.8e-42 144.4 0.2 4.5e-42 144.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG48238.1 - 1.6e-12 47.7 0.6 4.5e-12 46.3 0.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG48238.1 - 0.0066 15.9 0.1 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alg6_Alg8 PF03155.15 CEG48239.1 - 2.9e-110 369.5 36.7 4.4e-87 293.1 25.8 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family CdiA_C PF18451.1 CEG48240.1 - 0.14 12.3 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain CN_hydrolase PF00795.22 CEG48241.1 - 1.4e-67 227.8 0.0 1.6e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RBFA PF02033.18 CEG48242.1 - 4.2e-07 30.4 0.2 8.8e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Ribosome-binding factor A Proteasom_PSMB PF10508.9 CEG48243.1 - 4.1e-34 118.0 1.9 2.4e-33 115.4 1.9 1.9 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Neurochondrin PF05536.11 CEG48243.1 - 9e-07 27.6 1.6 0.019 13.3 0.0 2.5 2 0 0 2 2 2 2 Neurochondrin Cnd1 PF12717.7 CEG48243.1 - 0.17 11.9 2.0 4.4 7.3 0.5 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CEG48244.1 - 4.9e-22 78.1 0.0 3.9e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 Beta2-adaptin appendage, C-terminal sub-domain FHA PF00498.26 CEG48244.1 - 2.3e-18 66.3 0.1 6e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG48244.1 - 3.2e-06 27.4 0.0 8.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3246 PF11596.8 CEG48244.1 - 0.021 14.2 1.6 0.027 13.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Meis_PKNOX_N PF16493.5 CEG48244.1 - 0.022 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Tyrosinase PF00264.20 CEG48245.1 - 1.2e-23 84.6 0.0 4e-23 82.9 0.0 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Haem_oxygenas_2 PF14518.6 CEG48245.1 - 0.084 12.6 0.1 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Iron-containing redox enzyme DUF5363 PF17320.2 CEG48245.1 - 0.17 11.7 0.3 0.44 10.5 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5363) Exo_endo_phos PF03372.23 CEG48250.1 - 9e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-PARP PF00645.18 CEG48250.1 - 7.3e-10 39.6 1.4 1.6e-09 38.5 1.4 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ATP-synt_10 PF05176.14 CEG48252.1 - 2.4e-16 59.8 0.0 2.7e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein RVT_2 PF07727.14 CEG48255.1 - 2e-39 135.7 0.0 2.9e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2620 PF10941.8 CEG48255.1 - 0.029 14.5 0.1 0.096 12.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF2620 WavE PF07507.11 CEG48256.1 - 0.0025 17.0 0.0 0.0026 17.0 0.0 1.0 1 0 0 1 1 1 1 WavE lipopolysaccharide synthesis DUF3987 PF13148.6 CEG48257.1 - 0.0085 15.1 1.0 0.0085 15.1 1.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3987) DUF3209 PF11483.8 CEG48257.1 - 0.053 14.0 2.1 0.16 12.4 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) Pdase_C33_assoc PF14756.6 CEG48257.1 - 0.14 12.1 0.5 0.7 9.8 0.0 2.2 3 0 0 3 3 3 0 Peptidase_C33-associated domain FlaC_arch PF05377.11 CEG48257.1 - 0.17 12.3 4.1 0.26 11.7 1.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 CEG48257.1 - 8.8 6.6 11.3 14 5.9 0.7 3.0 1 1 0 2 2 2 0 Flagellar FliJ protein zf-C3HC4_2 PF13923.6 CEG48258.1 - 7.1e-07 29.0 8.4 1.3e-06 28.1 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG48258.1 - 4.1e-06 27.0 7.0 7.5e-06 26.2 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEG48258.1 - 5.3e-06 26.2 4.2 9.8e-06 25.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG48258.1 - 1.8e-05 24.9 6.4 4e-05 23.8 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG48258.1 - 0.00013 21.9 5.0 0.00023 21.1 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG48258.1 - 0.0012 18.7 7.9 0.0023 17.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG48258.1 - 0.018 15.0 3.4 0.043 13.9 3.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEG48258.1 - 0.022 14.5 5.0 0.047 13.4 5.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 CEG48258.1 - 0.041 13.7 6.0 0.079 12.8 6.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-FPG_IleRS PF06827.14 CEG48258.1 - 0.14 12.0 0.5 0.48 10.3 0.5 2.0 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_UBOX PF13445.6 CEG48258.1 - 0.38 10.8 6.3 1 9.5 6.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Acyl_transf_3 PF01757.22 CEG48259.1 - 8.8e-10 38.2 35.9 1.2e-09 37.7 35.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.22 CEG48260.1 - 4.4e-14 52.3 42.5 6.1e-14 51.8 42.5 1.2 1 0 0 1 1 1 1 Acyltransferase family Ku_C PF03730.14 CEG48262.1 - 0.093 13.4 2.1 0.12 13.0 0.9 1.8 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm DUF4366 PF14283.6 CEG48262.1 - 0.17 11.9 2.3 0.25 11.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ATP-synt_I PF03899.15 CEG48264.1 - 0.039 14.3 0.0 0.047 14.1 0.0 1.0 1 0 0 1 1 1 0 ATP synthase I chain Aminotran_4 PF01063.19 CEG48265.1 - 1.7e-27 96.7 0.0 2.3e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ocular_alb PF02101.15 CEG48266.1 - 0.3 9.9 3.4 0.38 9.6 3.4 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein CSG2 PF16965.5 CEG48266.1 - 0.59 9.0 2.1 0.62 9.0 2.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HAS-barrel PF09378.10 CEG48267.1 - 0.00028 21.0 3.8 1.8 8.7 0.0 4.7 5 0 0 5 5 5 2 HAS barrel domain Tudor_2 PF18104.1 CEG48267.1 - 0.1 12.3 4.0 17 5.2 0.0 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 CEG48267.1 - 0.13 12.1 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 CEG48267.1 - 0.16 11.8 0.1 1.7 8.5 0.0 2.7 2 1 1 3 3 3 0 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CEG48267.1 - 0.24 11.9 5.0 7 7.2 0.0 4.3 4 0 0 4 4 4 0 Agenet domain Bromodomain PF00439.25 CEG48269.1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Bromodomain Filament PF00038.21 CEG48270.1 - 2.2e-18 66.9 57.4 6e-18 65.5 57.4 1.7 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 CEG48270.1 - 7.1e-09 36.0 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain V-SNARE PF05008.15 CEG48270.1 - 0.0098 16.2 6.7 0.0098 16.2 6.7 5.6 2 1 4 6 6 4 1 Vesicle transport v-SNARE protein N-terminus MbeB_N PF04837.12 CEG48270.1 - 0.013 15.8 13.2 2.8 8.3 0.2 4.2 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Apolipoprotein PF01442.18 CEG48270.1 - 0.013 15.3 60.8 0.17 11.8 18.9 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Prp19 PF08606.11 CEG48270.1 - 0.015 15.3 3.1 0.015 15.3 3.1 4.0 3 0 0 3 3 3 0 Prp19/Pso4-like Baculo_PEP_C PF04513.12 CEG48270.1 - 0.027 14.5 0.4 0.027 14.5 0.4 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 CEG48270.1 - 0.55 9.2 45.7 0.2 10.6 13.7 3.5 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 MCPsignal PF00015.21 CEG48270.1 - 1.3 8.8 8.9 1.2 8.9 0.8 2.8 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 CEG48270.1 - 2.2 8.3 24.4 0.033 14.2 3.0 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CEG48270.1 - 3.5 6.9 44.2 0.68 9.2 15.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 CEG48270.1 - 3.9 7.8 18.0 0.33 11.2 0.6 3.7 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 CEG48270.1 - 6.1 6.4 32.5 0.77 9.3 5.9 3.8 1 1 3 4 4 4 0 fzo-like conserved region Phasin PF05597.11 CEG48270.1 - 7.1 6.7 28.7 1 9.3 7.1 3.5 2 2 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Hydrolase_4 PF12146.8 CEG48272.1 - 8.8e-51 172.5 0.0 1.1e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEG48272.1 - 1.9e-11 45.0 0.0 2.6e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CEG48272.1 - 5.5e-07 29.6 0.2 0.44 10.3 0.0 3.2 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 CEG48272.1 - 3.2e-06 27.0 0.2 0.013 15.1 0.3 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 CEG48272.1 - 0.0021 17.7 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CEG48272.1 - 0.0042 16.6 0.5 0.66 9.4 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family S_layer_C PF05124.12 CEG48272.1 - 0.0047 17.0 0.6 0.0065 16.5 0.6 1.3 1 0 0 1 1 1 1 S-layer like family, C-terminal region Chlorophyllase2 PF12740.7 CEG48272.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Kazal_2 PF07648.15 CEG48273.1 - 6.2e-05 23.0 3.0 0.00017 21.6 3.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG48273.1 - 0.0015 18.5 3.7 0.0023 17.9 3.0 1.7 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ank_2 PF12796.7 CEG48275.1 - 5.9e-16 58.8 0.4 1.8e-09 38.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG48275.1 - 2.1e-12 47.3 0.3 3.5e-09 37.0 0.2 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG48275.1 - 1.1e-11 44.7 0.9 0.00039 20.6 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG48275.1 - 1.9e-10 40.0 0.9 0.002 18.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CEG48275.1 - 1e-09 38.4 5.0 6.7e-05 23.2 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat FYVE PF01363.21 CEG48275.1 - 0.0002 21.4 9.7 0.00055 20.0 9.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger Jiv90 PF14901.6 CEG48275.1 - 0.019 15.1 0.1 0.066 13.4 0.1 1.9 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Ribosomal_L14 PF00238.19 CEG48276.1 - 6.3e-36 123.1 0.0 7.6e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF5348 PF17295.2 CEG48277.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Hexapep PF00132.24 CEG48278.1 - 3.4e-15 55.1 15.2 1.9e-06 27.4 0.5 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEG48278.1 - 3.5e-05 23.4 11.8 0.00043 20.0 1.0 3.8 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CEG48278.1 - 0.0032 16.5 0.2 0.005 15.8 0.2 1.3 1 1 0 1 1 1 1 L-fucokinase DUF484 PF04340.12 CEG48279.1 - 0.053 13.2 0.0 0.058 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Sec16_C PF12931.7 CEG48280.1 - 5e-28 98.6 0.1 5.9e-13 49.1 0.0 2.4 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 Sec16 PF12932.7 CEG48280.1 - 4.9e-20 72.3 0.0 2.1e-19 70.2 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RabGAP-TBC PF00566.18 CEG48280.1 - 0.031 13.9 0.2 0.071 12.7 0.0 1.6 2 0 0 2 2 2 0 Rab-GTPase-TBC domain AlgF PF11182.8 CEG48281.1 - 0.0036 17.1 0.1 0.0038 17.0 0.1 1.1 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF PMT2_N PF17987.1 CEG48281.1 - 0.04 14.1 0.2 0.045 13.9 0.2 1.1 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal HLH PF00010.26 CEG48281.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Ricin_B_lectin PF00652.22 CEG48282.1 - 6.8e-19 68.4 0.2 1.3e-15 57.7 1.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 CEG48282.1 - 0.00033 20.4 1.7 0.00067 19.3 0.2 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 WD40 PF00400.32 CEG48284.1 - 6.6e-17 61.6 5.6 0.00055 20.7 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48284.1 - 1.7e-07 31.5 0.4 0.14 12.5 0.2 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG48284.1 - 0.00025 20.1 0.1 0.037 13.0 0.1 2.5 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein GH115_C PF17829.1 CEG48284.1 - 0.025 14.4 0.2 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain Nup160 PF11715.8 CEG48284.1 - 0.033 12.9 4.1 4.7 5.7 0.1 3.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 IRF PF00605.17 CEG48284.1 - 0.046 14.0 1.3 0.1 12.9 0.4 2.1 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor DUF1841 PF08897.11 CEG48284.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) eIF-5_eIF-2B PF01873.17 CEG48285.1 - 3.1e-37 127.0 0.5 1.4e-36 124.9 0.2 2.3 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CEG48285.1 - 7.9e-17 61.2 3.2 7.9e-17 61.2 3.2 2.5 2 0 0 2 2 1 1 eIF4-gamma/eIF5/eIF2-epsilon TFIIF_alpha PF05793.12 CEG48285.1 - 0.00078 18.2 25.1 0.0011 17.7 25.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.22 CEG48285.1 - 0.0059 15.9 8.2 0.0073 15.6 8.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DDHD PF02862.17 CEG48285.1 - 0.13 12.4 4.6 0.22 11.7 4.6 1.5 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.9 CEG48285.1 - 0.14 11.8 24.8 0.28 10.8 24.8 1.5 1 0 0 1 1 1 0 DDRGK domain Apt1 PF10351.9 CEG48285.1 - 0.21 10.4 13.5 0.28 10.0 13.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5427 PF10310.9 CEG48285.1 - 0.25 10.3 22.1 0.42 9.5 22.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) NPR3 PF03666.13 CEG48285.1 - 0.29 9.9 17.1 0.41 9.4 17.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4778 PF16008.5 CEG48285.1 - 0.31 11.1 10.5 0.49 10.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF3827 PF12877.7 CEG48285.1 - 0.43 8.9 12.7 0.55 8.5 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.14 CEG48285.1 - 1.2 7.4 17.1 1.6 6.9 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 CEG48285.1 - 1.3 9.5 6.8 1.8 9.1 6.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 CEG48285.1 - 2.6 5.9 11.9 4 5.2 11.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CEG48285.1 - 2.6 7.0 14.4 3.7 6.5 14.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4569 PF15133.6 CEG48285.1 - 2.7 7.6 10.9 4 7.1 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) MMM1 PF10296.9 CEG48285.1 - 3.6 6.5 9.1 5.6 5.9 9.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 VIR_N PF15912.5 CEG48285.1 - 5 6.6 10.4 7.7 6.0 10.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Vfa1 PF08432.10 CEG48285.1 - 5.9 7.2 28.0 13 6.1 28.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.16 CEG48285.1 - 7.3 6.0 22.3 12 5.3 22.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 CEG48285.1 - 8.8 5.0 17.2 12 4.5 17.2 1.2 1 0 0 1 1 1 0 Presenilin Mito_fiss_Elm1 PF06258.11 CEG48286.1 - 3.9e-78 262.7 0.0 4.5e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 dTDP_sugar_isom PF00908.17 CEG48286.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 1 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Nucleopor_Nup85 PF07575.13 CEG48287.1 - 1.2e-68 232.1 17.5 1.8e-68 231.5 17.5 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Ank_2 PF12796.7 CEG48287.1 - 0.15 12.6 0.0 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ras PF00071.22 CEG48288.1 - 3.5e-41 140.5 0.2 4.1e-41 140.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG48288.1 - 4.2e-35 120.6 0.0 6.1e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG48288.1 - 7.3e-09 35.3 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG48288.1 - 2.9e-07 30.1 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEG48288.1 - 5.8e-05 22.7 0.0 0.0063 16.1 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEG48288.1 - 0.00025 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CEG48288.1 - 0.0059 16.6 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 CEG48288.1 - 0.019 14.9 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 CEG48288.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 CEG48288.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Borrelia_orfD PF02999.14 CEG48288.1 - 0.11 12.9 0.3 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 Borrelia orf-D family NOG1 PF06858.14 CEG48288.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) zf-RanBP PF00641.18 CEG48289.1 - 3.7e-12 45.3 23.7 2.8e-07 29.7 4.1 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others ANAPC4_WD40 PF12894.7 CEG48289.1 - 8.1e-07 29.3 0.2 8.3e-06 26.0 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Collar PF07484.12 CEG48289.1 - 0.00098 19.1 0.0 1.5 8.9 0.0 3.5 3 0 0 3 3 3 2 Phage Tail Collar Domain DZR PF12773.7 CEG48289.1 - 0.098 12.7 5.2 1.8 8.7 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 CEG48289.1 - 0.14 11.5 11.6 1.2 8.6 1.2 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CEG48289.1 - 0.78 9.9 11.0 3.2 7.9 0.1 3.9 2 2 2 4 4 4 0 Sec23/Sec24 zinc finger EF-hand_7 PF13499.6 CEG48289.1 - 0.98 9.9 7.9 1.7 9.1 0.2 3.7 5 1 0 5 5 5 0 EF-hand domain pair C1_2 PF03107.16 CEG48289.1 - 1.8 9.0 5.3 18 5.8 0.3 2.9 2 0 0 2 2 2 0 C1 domain UCMA PF17085.5 CEG48289.1 - 2.6 8.0 9.3 8 6.5 0.6 3.3 3 0 0 3 3 3 0 Unique cartilage matrix associated protein Methyltransf_3 PF01596.17 CEG48290.1 - 1.3e-46 158.4 0.1 6.3e-46 156.2 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_24 PF13578.6 CEG48290.1 - 6.3e-14 52.9 0.0 1.5e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEG48290.1 - 1.6e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CEG48290.1 - 2.3e-05 25.0 0.0 4.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG48290.1 - 0.00022 21.9 0.0 0.00052 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 CEG48290.1 - 0.00036 20.0 0.0 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 CEG48290.1 - 0.00051 19.9 0.3 0.0014 18.5 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG48290.1 - 0.00098 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CEG48290.1 - 0.0043 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG48290.1 - 0.013 16.2 0.1 0.034 14.8 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CEG48290.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CEG48290.1 - 0.024 14.3 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 CEG48290.1 - 0.032 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0176_N PF17773.1 CEG48291.1 - 5.4e-20 71.5 0.0 1.4e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CEG48291.1 - 1.6e-15 57.2 13.9 1.6e-15 57.2 13.9 1.6 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 CEG48291.1 - 4.1e-07 30.5 0.1 1e-06 29.2 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PAP_assoc PF03828.19 CEG48292.1 - 5.2e-15 55.4 0.8 1.3e-14 54.1 0.3 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEG48292.1 - 4e-07 30.2 0.1 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CEG48292.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain RRM_1 PF00076.22 CEG48293.1 - 2.1e-23 81.9 0.1 3.2e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG48293.1 - 2.7e-05 23.7 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEG48293.1 - 0.027 14.5 0.1 0.062 13.4 0.1 1.7 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 CEG48293.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif Glyco_transf_22 PF03901.17 CEG48294.1 - 8.8e-95 318.4 12.9 1.5e-94 317.6 12.9 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family VPS13_C PF16909.5 CEG48294.1 - 3.1e-54 183.4 0.2 1.4e-50 171.6 0.0 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CEG48294.1 - 1.1e-39 136.5 0.1 1.3e-33 116.5 0.1 4.4 5 0 0 5 5 5 2 SHR-binding domain of vacuolar-sorting associated protein 13 PH PF00169.29 CEG48294.1 - 1e-17 64.6 0.0 1.4e-06 28.8 0.0 4.1 3 0 0 3 3 3 3 PH domain Chorein_N PF12624.7 CEG48294.1 - 6e-15 55.4 0.0 3.4e-14 52.9 0.0 2.4 2 0 0 2 2 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CEG48294.1 - 1.9e-11 44.2 0.4 6.7e-10 39.2 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 CEG48294.1 - 3.4e-06 27.3 0.0 1.4e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PMT_2 PF13231.6 CEG48294.1 - 0.00068 19.9 7.5 0.0014 18.9 7.5 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PH_8 PF15409.6 CEG48294.1 - 0.0024 18.1 0.3 15 5.9 0.0 3.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 CEG48294.1 - 0.01 16.3 0.0 4.6 7.7 0.0 3.9 3 0 0 3 3 3 0 Pleckstrin homology domain DEP PF00610.21 CEG48294.1 - 0.02 14.9 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 CEG48294.1 - 0.023 14.5 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PH_3 PF14593.6 CEG48294.1 - 0.029 14.5 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 PH domain PDZ PF00595.24 CEG48294.1 - 0.057 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain C2 PF00168.30 CEG48294.1 - 0.086 13.1 0.0 0.3 11.4 0.0 2.1 1 0 0 1 1 1 0 C2 domain DER1 PF04511.15 CEG48295.1 - 4.8e-49 166.9 8.8 5.5e-49 166.7 8.8 1.0 1 0 0 1 1 1 1 Der1-like family RNA_pol_A_bac PF01000.26 CEG48296.1 - 2.5e-28 98.7 0.0 1.3e-27 96.3 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEG48296.1 - 6.6e-21 73.5 0.0 8.5e-21 73.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Atg14 PF10186.9 CEG48297.1 - 2.3e-29 102.5 6.8 3.5e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 CEG48297.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Apg6 BARA domain Spc7 PF08317.11 CEG48297.1 - 0.049 12.5 3.0 0.078 11.8 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1090 PF06476.12 CEG48297.1 - 0.58 10.3 6.6 0.17 12.0 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) LUC7 PF03194.15 CEG48300.1 - 9.4e-71 238.4 6.9 9.4e-71 238.4 6.9 1.9 1 1 1 2 2 2 1 LUC7 N_terminus DUF2089 PF09862.9 CEG48300.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) LCM PF04072.14 CEG48301.1 - 3.4e-38 131.5 0.0 4.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Peptidase_C2 PF00648.21 CEG48302.1 - 4.7e-54 183.4 0.0 1.8e-53 181.5 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease WW PF00397.26 CEG48302.1 - 5.2e-12 45.6 0.8 1.4e-11 44.2 0.8 1.8 1 0 0 1 1 1 1 WW domain C2 PF00168.30 CEG48302.1 - 2.4e-08 34.2 0.0 7.6e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 C2 domain Calpain_III PF01067.22 CEG48302.1 - 2.7e-05 24.4 0.0 8.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Calpain large subunit, domain III Glyco_hyd_101C PF17451.2 CEG48302.1 - 0.049 13.9 0.3 0.15 12.3 0.3 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain DUF2681 PF10883.8 CEG48302.1 - 0.38 11.2 4.2 0.98 9.9 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SMC_ScpA PF02616.14 CEG48303.1 - 0.05 13.5 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Asp PF00026.23 CEG48304.1 - 3.6e-29 102.2 1.2 7.7e-29 101.1 1.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease WBP-1 PF11669.8 CEG48304.1 - 0.011 16.4 0.1 0.011 16.4 0.1 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 TAXi_C PF14541.6 CEG48304.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Phage_holin_3_6 PF07332.11 CEG48304.1 - 0.24 11.4 1.4 0.42 10.7 1.4 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PDR_CDR PF06422.12 CEG48304.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 CDR ABC transporter PDZ PF00595.24 CEG48305.1 - 5.9e-19 68.2 0.0 0.0023 18.3 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CEG48305.1 - 1.5e-14 53.5 0.0 0.0076 16.1 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CEG48305.1 - 3.6e-10 40.0 0.1 0.18 12.2 0.0 4.4 4 0 0 4 4 4 3 PDZ domain FYVE PF01363.21 CEG48306.1 - 3.9e-08 33.3 20.4 1.1e-07 31.8 18.5 2.6 2 0 0 2 2 2 1 FYVE zinc finger Exo_endo_phos PF03372.23 CEG48307.1 - 0.0024 17.4 0.0 0.016 14.7 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ThiF PF00899.21 CEG48309.1 - 3.8e-37 128.0 0.1 7.2e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CEG48309.1 - 0.0011 19.2 1.3 0.008 16.4 1.3 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CEG48309.1 - 0.0039 17.5 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 CEG48309.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CEG48309.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 CEG48309.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pex14_N PF04695.13 CEG48309.1 - 0.1 13.2 0.2 1.2 9.8 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAO PF01266.24 CEG48309.1 - 0.51 9.9 2.1 6.1 6.3 0.3 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase CH PF00307.31 CEG48310.1 - 3.7e-08 33.5 0.0 8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CEG48310.1 - 0.0046 16.8 0.3 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 CEG48310.1 - 0.0069 16.5 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 CH-like domain in sperm protein DUF2200 PF09966.9 CEG48310.1 - 0.1 12.8 0.1 0.5 10.5 0.0 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) GST_C_3 PF14497.6 CEG48312.1 - 1.9e-24 85.7 0.2 1.6e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEG48312.1 - 6.5e-20 71.3 0.0 7.9e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEG48312.1 - 3.8e-09 36.8 0.0 0.0006 20.2 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEG48312.1 - 3.9e-06 27.1 0.0 0.12 12.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CEG48312.1 - 0.00015 21.9 0.2 0.0013 18.9 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEG48312.1 - 0.00027 20.9 0.0 0.00097 19.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ost5 PF05251.12 CEG48313.1 - 0.012 15.8 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 DUSP PF06337.12 CEG48316.1 - 1.1e-12 48.3 0.0 2.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 CEG48316.1 - 5.5e-08 33.0 0.0 3.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain PX PF00787.24 CEG48317.1 - 5.7e-08 32.7 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 PX domain Late_protein_L2 PF00513.18 CEG48317.1 - 0.048 12.7 1.1 0.067 12.2 1.1 1.2 1 0 0 1 1 1 0 Late Protein L2 YL1 PF05764.13 CEG48317.1 - 0.098 12.8 1.3 0.14 12.3 1.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pox_A_type_inc PF04508.12 CEG48321.1 - 0.19 11.6 3.1 12 5.9 0.0 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TetR_C_24 PF17932.1 CEG48321.1 - 0.72 10.1 4.3 1.9 8.8 0.1 3.2 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain SF-assemblin PF06705.11 CEG48322.1 - 1.7e-38 132.4 23.3 1.9e-38 132.2 23.3 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Phage_Mu_Gam PF07352.12 CEG48322.1 - 0.17 11.7 18.8 0.16 11.9 1.3 3.4 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein Baculo_PEP_C PF04513.12 CEG48322.1 - 4.7 7.3 13.3 4.7 7.3 5.9 3.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CREPT PF16566.5 CEG48322.1 - 4.9 7.3 19.5 0.16 12.2 6.6 3.0 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ECM11 PF15463.6 CEG48322.1 - 5.1 7.7 16.1 0.37 11.4 3.3 3.8 1 1 3 4 4 4 0 Extracellular mutant protein 11 DOT1 PF08123.13 CEG48323.1 - 3.3e-11 43.1 0.0 5.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CEG48323.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG48323.1 - 0.0071 17.0 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG48323.1 - 0.025 15.2 0.0 0.064 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 CEG48323.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 CEG48323.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FANCI_S1-cap PF14674.6 CEG48324.1 - 0.16 12.1 0.2 0.52 10.4 0.2 1.9 1 0 0 1 1 1 0 FANCI solenoid 1 cap RXLR PF16810.5 CEG48333.1 - 1.6 9.2 11.4 20 5.6 11.4 2.2 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF1754 PF08555.10 CEG48333.1 - 3.3 8.6 13.8 0.99 10.2 10.8 1.7 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PI3_PI4_kinase PF00454.27 CEG48334.1 - 7.1e-37 127.6 0.1 8.3e-27 94.6 0.1 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEG48334.1 - 9.2e-06 25.2 0.5 1.8e-05 24.2 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CEG48334.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) BT1 PF03092.16 CEG48335.1 - 1.7e-87 293.9 21.0 5.4e-50 170.1 6.6 3.0 1 1 2 3 3 3 3 BT1 family NPP1 PF05630.11 CEG48336.1 - 3.3e-70 236.2 0.1 5.4e-70 235.5 0.1 1.3 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Jacalin PF01419.17 CEG48336.1 - 1.2e-06 28.5 1.2 1.2e-06 28.5 1.2 1.8 2 0 0 2 2 2 1 Jacalin-like lectin domain DUF3388 PF11868.8 CEG48336.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) ParBc PF02195.18 CEG48337.1 - 8.9e-09 35.5 0.1 0.0062 16.8 0.0 2.5 2 0 0 2 2 2 2 ParB-like nuclease domain RHS_repeat PF05593.14 CEG48337.1 - 0.19 12.3 0.6 4.6 7.9 0.1 2.4 2 0 0 2 2 2 0 RHS Repeat DUF1015 PF06245.11 CEG48337.1 - 7.6 5.3 9.7 1.6 7.5 0.3 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1015) Peptidase_A22B PF04258.13 CEG48338.1 - 5.6e-87 291.9 7.0 7.4e-87 291.5 7.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CEG48338.1 - 0.0009 18.8 10.3 0.0009 18.8 10.3 2.7 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Thioredoxin PF00085.20 CEG48340.1 - 4.9e-62 206.4 1.0 1.5e-31 108.4 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CEG48340.1 - 2.7e-30 105.7 4.2 2.1e-19 70.1 0.1 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CEG48340.1 - 6.1e-16 58.8 2.7 2e-06 28.2 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEG48340.1 - 5.5e-12 45.7 0.3 7.8e-06 26.0 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CEG48340.1 - 1.1e-08 35.0 0.9 0.0018 18.1 0.0 3.2 3 2 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CEG48340.1 - 2.1e-08 34.4 0.2 0.0027 18.0 0.0 4.3 3 2 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CEG48340.1 - 2.2e-06 27.2 0.1 0.026 13.9 0.1 2.6 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CEG48340.1 - 4.3e-06 26.5 1.7 0.016 14.9 0.0 3.7 3 1 0 3 3 3 1 Redoxin ERp29_N PF07912.13 CEG48340.1 - 7.3e-05 22.9 0.5 0.46 10.6 0.0 3.7 4 0 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 CEG48340.1 - 0.0066 16.2 0.0 0.89 9.3 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 CEG48340.1 - 0.015 15.2 0.3 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 CEG48340.1 - 0.016 15.4 0.7 0.89 9.8 0.0 3.2 2 1 0 2 2 2 0 Glutaredoxin DUF2569 PF10754.9 CEG48341.1 - 0.084 13.3 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) zf-CCCH PF00642.24 CEG48342.1 - 2.5e-17 62.3 17.5 4.3e-11 42.4 4.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG48342.1 - 1.3e-09 37.8 18.1 4.3e-05 23.4 6.9 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEG48342.1 - 3.4e-07 29.9 16.6 0.0018 18.1 3.5 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEG48342.1 - 0.0019 18.6 11.8 0.05 14.1 2.1 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEG48342.1 - 0.0037 17.9 9.5 0.19 12.4 1.0 2.4 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 CEG48342.1 - 0.21 12.1 2.0 14 6.2 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCHH PF10283.9 CEG48342.1 - 3.4 7.8 9.7 6.6 6.8 1.0 2.5 2 0 0 2 2 2 0 PBZ domain fn3 PF00041.21 CEG48344.1 - 0.036 14.4 0.0 0.074 13.4 0.0 1.7 1 1 0 1 1 1 0 Fibronectin type III domain DUF4246 PF14033.6 CEG48345.1 - 0.098 11.7 0.3 0.12 11.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) MFS_1 PF07690.16 CEG48348.1 - 4.6e-19 68.6 20.5 4.6e-19 68.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CEG48349.1 - 2.5e-21 76.0 28.9 2.5e-21 76.0 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 CEG48350.1 - 1.7e-100 337.4 0.6 2.2e-100 337.0 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 CEG48350.1 - 0.083 12.4 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 CEG48351.1 - 8.1e-114 381.3 1.3 1.1e-113 380.8 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ufm1 PF03671.14 CEG48351.1 - 1.3e-41 140.5 0.7 4.5e-40 135.6 0.1 2.6 3 0 0 3 3 3 1 Ubiquitin fold modifier 1 protein Mtc PF03820.17 CEG48352.1 - 2.6e-125 417.6 2.3 2.1e-109 365.4 1.0 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier CRT-like PF08627.10 CEG48353.1 - 0.092 11.7 0.3 0.12 11.3 0.3 1.1 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Peptidase_S10 PF00450.22 CEG48354.1 - 4e-119 398.7 0.2 5.2e-119 398.4 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase peroxidase PF00141.23 CEG48356.1 - 7.2e-32 110.9 0.0 8.8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Alfin PF12165.8 CEG48357.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Alfin Aminotran_3 PF00202.21 CEG48358.1 - 7.6e-10 38.0 0.0 9.7e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Chordopox_A33R PF05966.12 CEG48358.1 - 0.072 12.4 0.3 9.2 5.5 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Piwi PF02171.17 CEG48361.1 - 0.16 11.2 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Piwi domain PH PF00169.29 CEG48362.1 - 1.2e-08 35.4 0.1 4.1e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG48362.1 - 0.0021 18.4 0.1 0.005 17.2 0.1 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG48362.1 - 0.0072 16.6 0.1 0.099 12.9 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain TRP PF06011.12 CEG48365.1 - 0.033 12.9 4.7 0.062 12.0 4.7 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel KASH PF10541.9 CEG48365.1 - 0.28 11.5 2.8 9.4 6.6 0.1 3.2 3 0 0 3 3 3 0 Nuclear envelope localisation domain BTB PF00651.31 CEG48367.1 - 2.5e-17 63.1 0.0 1.7e-16 60.4 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Rad60-SLD PF11976.8 CEG48367.1 - 0.0004 20.2 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Fer4_19 PF06902.11 CEG48367.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster BACK PF07707.15 CEG48367.1 - 0.48 10.5 2.5 3.4 7.8 0.2 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch AAA PF00004.29 CEG48368.1 - 5.6e-38 130.4 0.0 1.1e-37 129.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 CEG48368.1 - 4.4e-18 65.6 0.0 3.6e-17 62.6 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CEG48368.1 - 1.1e-08 34.3 0.4 3.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase AAA_lid_3 PF17862.1 CEG48368.1 - 1.7e-08 34.1 0.0 4.9e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CEG48368.1 - 1.5e-07 31.3 0.0 5.4e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CEG48368.1 - 5.4e-06 26.4 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEG48368.1 - 8.5e-06 25.6 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEG48368.1 - 0.0011 19.3 0.4 0.05 13.9 0.3 3.4 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 CEG48368.1 - 0.0026 17.0 0.4 0.0077 15.5 0.1 1.8 2 1 0 2 2 2 1 TIP49 P-loop domain Kdo PF06293.14 CEG48368.1 - 0.0035 16.7 0.2 0.0083 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_2 PF07724.14 CEG48368.1 - 0.0036 17.4 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEG48368.1 - 0.0098 16.3 1.3 0.083 13.3 0.5 2.7 2 1 0 2 2 1 1 AAA ATPase domain APH PF01636.23 CEG48368.1 - 0.016 15.1 1.2 1.3 8.9 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family AAA_14 PF13173.6 CEG48368.1 - 0.017 15.2 0.0 0.19 11.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEG48368.1 - 0.031 14.8 0.0 0.34 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEG48368.1 - 0.096 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein FMN_dh PF01070.18 CEG48370.1 - 6.3e-134 446.4 0.0 7.1e-134 446.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CEG48370.1 - 1.4e-05 24.3 1.6 2.9e-05 23.2 1.5 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CEG48370.1 - 0.00011 21.5 0.1 0.00017 20.9 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CEG48370.1 - 0.00024 20.5 0.4 0.049 12.9 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CEG48370.1 - 0.014 14.9 0.1 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 CEG48370.1 - 0.016 14.6 0.7 0.024 14.0 0.7 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Jacalin PF01419.17 CEG48372.1 - 0.00012 22.1 0.3 0.014 15.3 0.1 2.2 1 1 1 2 2 2 2 Jacalin-like lectin domain GRIM-19 PF06212.12 CEG48373.1 - 0.0021 18.0 2.6 0.003 17.5 0.4 2.3 1 1 1 2 2 2 1 GRIM-19 protein Troponin PF00992.20 CEG48373.1 - 0.0075 16.6 17.2 0.0075 16.6 17.2 2.7 1 1 1 2 2 2 1 Troponin HJURP_mid PF12346.8 CEG48373.1 - 7.6 7.0 8.5 1 9.8 3.0 2.2 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat MMS1_N PF10433.9 CEG48374.1 - 1.9e-106 356.6 0.2 7.1e-106 354.7 0.1 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEG48374.1 - 3.2e-82 276.4 0.3 3.9e-81 272.9 0.1 2.7 3 0 0 3 3 3 1 CPSF A subunit region MxiM PF11441.8 CEG48374.1 - 0.081 13.2 0.2 7.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Pilot protein MxiM HAD_2 PF13419.6 CEG48375.1 - 0.01 15.9 1.3 0.061 13.4 0.7 2.6 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HMG-CoA_red PF00368.18 CEG48376.1 - 3.1e-94 316.0 5.9 6e-94 315.1 5.9 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ACPS PF01648.20 CEG48377.1 - 3.1e-16 59.5 0.2 4.8e-16 58.9 0.2 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 CEG48377.1 - 0.026 14.7 0.1 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Inv-AAD PF18785.1 CEG48380.1 - 4e-20 72.0 1.4 3.6e-18 65.7 1.4 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 CEG48380.1 - 2.4e-09 37.0 0.8 1.3e-08 34.6 0.8 1.9 1 1 1 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEG48380.1 - 0.00019 21.2 0.3 0.00027 20.7 0.3 1.3 1 0 0 1 1 1 1 MafB19-like deaminase CytochromB561_N PF09786.9 CEG48381.1 - 0.003 16.6 1.9 0.0048 16.0 1.8 1.4 1 1 0 1 1 1 1 Cytochrome B561, N terminal Beach PF02138.18 CEG48382.1 - 1.2e-113 379.1 0.1 4.3e-113 377.3 0.0 2.0 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 CEG48382.1 - 8.1e-23 80.4 0.0 2.6e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CEG48382.1 - 1.1e-07 31.5 11.7 2.2e-06 27.1 2.8 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4704) WD40 PF00400.32 CEG48382.1 - 8.9e-05 23.2 2.7 0.087 13.7 0.4 4.4 3 0 0 3 3 3 1 WD domain, G-beta repeat GRAM PF02893.20 CEG48382.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 GRAM domain PTR2 PF00854.21 CEG48383.1 - 1.1e-62 212.2 12.8 4.3e-61 206.9 10.4 2.5 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 CEG48383.1 - 1.5e-06 27.4 44.2 0.014 14.4 40.1 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.17 CEG48385.1 - 0.065 12.3 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3627 PF12299.8 CEG48390.1 - 0.028 14.5 0.2 0.038 14.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) ETC_C1_NDUFA4 PF04800.12 CEG48391.1 - 3.6e-28 97.7 1.2 3.9e-28 97.5 0.2 1.6 2 0 0 2 2 2 1 ETC complex I subunit conserved region COPI_assoc PF08507.10 CEG48392.1 - 1.2e-26 93.3 9.5 1.5e-26 92.9 9.5 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4064 PF13273.6 CEG48392.1 - 0.0024 18.1 0.1 0.0024 18.1 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) DUF4131 PF13567.6 CEG48392.1 - 0.013 15.2 2.7 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2721 PF11026.8 CEG48392.1 - 0.094 12.6 0.2 0.094 12.6 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) COX2-transmemb PF09125.10 CEG48392.1 - 0.26 11.1 4.4 0.57 10.0 4.4 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DUF2417 PF10329.9 CEG48392.1 - 9.8 5.5 7.9 23 4.3 7.8 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) DSPc PF00782.20 CEG48393.1 - 4.5e-30 104.2 0.6 1e-29 103.0 0.4 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CEG48393.1 - 1.8e-07 31.6 0.0 7.4e-07 29.7 0.0 2.1 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 CEG48393.1 - 0.00024 20.7 0.1 0.00039 20.0 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEG48393.1 - 0.021 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate MORN PF02493.20 CEG48394.1 - 8e-17 60.1 27.0 1.1e-06 28.1 1.1 5.3 6 0 0 6 6 6 3 MORN repeat DUF3048_C PF17479.2 CEG48394.1 - 0.21 12.0 2.7 1.3 9.5 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain LcrG PF07216.12 CEG48396.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 LcrG protein RVT_2 PF07727.14 CEG48397.1 - 6.3e-16 58.8 0.0 7.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FA_desaturase PF00487.24 CEG48398.1 - 2.8e-31 109.3 18.8 2.8e-31 109.3 18.8 1.3 1 1 0 1 1 1 1 Fatty acid desaturase TGF_beta_GS PF08515.12 CEG48399.1 - 0.17 11.4 1.1 0.43 10.1 1.1 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Lactonase PF10282.9 CEG48402.1 - 3.9e-07 29.7 0.0 4.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Retrotrans_gag PF03732.17 CEG48403.1 - 4.9e-08 33.2 0.0 1e-07 32.1 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein Alpha-amylase_N PF02903.14 CEG48404.1 - 0.025 14.7 0.7 0.26 11.4 0.1 2.7 2 1 1 3 3 3 0 Alpha amylase, N-terminal ig-like domain MatK_N PF01824.18 CEG48404.1 - 0.88 9.2 6.5 1.6 8.3 0.1 3.4 3 1 1 4 4 4 0 MatK/TrnK amino terminal region Retrotrans_gag PF03732.17 CEG48408.1 - 1e-08 35.3 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PNMA PF14893.6 CEG48408.1 - 0.039 13.4 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 PNMA ANAPC4_WD40 PF12894.7 CEG48409.1 - 1e-06 29.0 0.3 2.1 8.7 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG48409.1 - 0.00049 20.8 2.2 1.8 9.6 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat SPOR PF05036.13 CEG48409.1 - 0.041 14.3 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain Pkinase PF00069.25 CEG48410.1 - 3.2e-63 213.6 0.0 3.9e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48410.1 - 6.2e-33 114.2 0.0 7.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG48410.1 - 1.8e-07 30.7 0.2 2.8e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG48410.1 - 7.3e-07 28.8 0.1 1.6e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEG48410.1 - 6.7e-06 26.2 0.0 0.047 13.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG48410.1 - 2.2e-05 23.4 0.1 3.6e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CEG48410.1 - 0.014 14.9 0.1 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 CEG48410.1 - 0.02 14.5 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CEG48410.1 - 0.16 11.6 0.0 0.42 10.2 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_C48 PF02902.19 CEG48411.1 - 9.4e-41 140.0 3.6 2e-40 139.0 3.6 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CtIP_N PF10482.9 CEG48411.1 - 3.1 7.9 9.9 4.3 7.4 1.3 2.6 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain COX17 PF05051.13 CEG48412.1 - 2.4e-20 72.6 6.5 3.3e-20 72.2 6.5 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Hep_core_N PF08290.11 CEG48412.1 - 0.084 12.8 5.6 0.12 12.3 3.9 2.0 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger PAE PF03283.13 CEG48414.1 - 1.8e-12 47.1 0.8 2.8e-12 46.5 0.8 1.4 1 1 0 1 1 1 1 Pectinacetylesterase DUF2369 PF10179.9 CEG48414.1 - 0.04 14.3 0.2 0.093 13.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Tim17 PF02466.19 CEG48415.1 - 2.6e-30 105.0 3.3 3.1e-30 104.8 3.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 CEG48415.1 - 0.0099 16.2 1.5 0.023 15.0 0.1 2.2 2 1 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 adh_short_C2 PF13561.6 CEG48416.1 - 2.4e-44 151.6 1.3 3.2e-44 151.2 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG48416.1 - 4.2e-31 107.9 1.6 5.9e-31 107.5 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Pex14_N PF04695.13 CEG48416.1 - 3.6e-14 53.7 1.9 3.8e-14 53.6 0.6 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region KR PF08659.10 CEG48416.1 - 0.004 17.1 0.0 0.0068 16.3 0.0 1.5 1 1 0 1 1 1 1 KR domain TFR_dimer PF04253.15 CEG48417.1 - 8.8e-29 100.1 0.0 1.9e-28 99.0 0.0 1.6 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CEG48417.1 - 4.9e-22 78.6 0.0 1.6e-21 76.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEG48417.1 - 7.2e-11 42.0 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 CEG48417.1 - 0.0037 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.28 CEG48417.1 - 0.031 13.9 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Lectin_N PF03954.14 CEG48417.1 - 0.094 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Kelch_4 PF13418.6 CEG48418.1 - 4e-40 135.6 4.9 2.3e-06 27.5 0.0 7.1 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CEG48418.1 - 7.2e-37 125.0 2.4 5e-08 33.0 0.0 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CEG48418.1 - 2.4e-30 103.8 0.0 5.7e-09 35.9 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CEG48418.1 - 1.3e-29 101.7 0.6 0.00013 21.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 CEG48418.1 - 1.4e-19 69.3 2.6 0.0012 18.3 0.1 6.4 6 1 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 CEG48418.1 - 2.2e-18 66.1 0.1 2.2e-18 66.1 0.1 3.6 3 2 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 CEG48418.1 - 9.5e-13 47.6 7.7 0.017 15.1 0.2 6.9 6 2 0 6 6 6 3 Kelch motif FYVE PF01363.21 CEG48421.1 - 0.00013 22.1 11.0 0.00038 20.5 11.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG48421.1 - 0.00019 21.6 8.0 0.00047 20.4 8.0 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-UDP PF14569.6 CEG48421.1 - 0.079 13.1 5.4 0.18 11.9 5.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-B_box PF00643.24 CEG48421.1 - 0.3 11.3 10.2 0.043 14.0 5.2 2.1 2 0 0 2 2 2 0 B-box zinc finger C1_2 PF03107.16 CEG48421.1 - 0.41 11.0 4.8 1.3 9.4 4.8 1.8 1 0 0 1 1 1 0 C1 domain Prok-RING_4 PF14447.6 CEG48421.1 - 3.6 7.5 8.4 7.8 6.5 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Astacin PF01400.24 CEG48423.1 - 5.1e-21 75.2 5.8 1.2e-17 64.1 2.0 3.2 2 1 1 3 3 3 2 Astacin (Peptidase family M12A) Metallopep PF12044.8 CEG48423.1 - 0.0052 15.4 0.3 0.0085 14.7 0.3 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 CEG48423.1 - 0.0097 16.4 0.0 0.029 14.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CEG48423.1 - 0.024 14.5 3.7 0.19 11.6 3.1 2.3 1 1 0 2 2 2 0 Matrixin DUF4953 PF16313.5 CEG48423.1 - 0.27 10.4 1.4 0.43 9.8 0.6 1.7 2 0 0 2 2 2 0 Met-zincin DUF1254 PF06863.12 CEG48425.1 - 0.049 13.7 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) fn3 PF00041.21 CEG48427.1 - 2e-05 24.8 0.2 0.031 14.6 0.1 3.0 2 1 0 2 2 2 2 Fibronectin type III domain SRP19 PF01922.17 CEG48428.1 - 6.2e-29 100.8 0.0 1.1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Cofilin_ADF PF00241.20 CEG48429.1 - 7.8e-28 96.7 0.8 1.2e-12 47.7 0.0 3.0 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PWWP PF00855.17 CEG48430.1 - 1.1e-16 61.0 2.5 9.1e-16 58.0 0.1 3.1 2 0 0 2 2 2 1 PWWP domain Ribosomal_S2 PF00318.20 CEG48431.1 - 2.3e-29 102.2 0.1 8.1e-15 54.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CEG48431.1 - 0.00044 21.5 10.7 0.00086 20.6 10.7 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus FYVE PF01363.21 CEG48432.1 - 0.00013 22.1 11.2 0.00028 21.0 11.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG48432.1 - 0.0024 18.1 4.9 0.0068 16.6 4.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger GAF PF01590.26 CEG48434.1 - 0.0035 18.0 0.0 0.007 17.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CEG48434.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.6 2 0 0 2 2 2 0 GAF domain ABC_tran PF00005.27 CEG48435.1 - 2.3e-52 177.1 0.0 2e-26 93.2 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG48435.1 - 1.3e-15 58.0 4.8 0.00018 21.5 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CEG48435.1 - 8.8e-12 44.9 9.8 3.3e-09 36.7 4.9 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CEG48435.1 - 7.6e-07 28.8 0.8 0.05 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CEG48435.1 - 2.8e-06 26.9 8.4 0.073 12.5 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 CEG48435.1 - 2e-05 23.9 0.0 0.086 12.0 0.0 3.0 2 1 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 CEG48435.1 - 0.00012 22.0 0.3 0.084 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CEG48435.1 - 0.00023 21.2 0.3 0.26 11.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CEG48435.1 - 0.00048 20.7 0.4 0.0076 16.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CEG48435.1 - 0.0015 18.4 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CEG48435.1 - 0.0021 18.2 0.7 7.3 6.9 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 CEG48435.1 - 0.0034 17.5 0.1 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 CEG48435.1 - 0.0039 17.7 13.9 0.14 12.6 0.4 3.1 2 1 1 3 3 3 2 AAA domain AAA_28 PF13521.6 CEG48435.1 - 0.0043 17.3 0.1 4.7 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG48435.1 - 0.0053 17.1 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CEG48435.1 - 0.0058 16.7 0.0 1.4 8.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain MeaB PF03308.16 CEG48435.1 - 0.0093 15.0 0.1 0.82 8.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CEG48435.1 - 0.01 15.7 1.6 1.9 8.4 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 CEG48435.1 - 0.012 15.9 0.2 9.2 6.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 CEG48435.1 - 0.013 14.2 0.0 3.2 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CEG48435.1 - 0.015 15.0 0.4 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CEG48435.1 - 0.02 14.8 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CEG48435.1 - 0.022 15.1 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEG48435.1 - 0.042 14.2 0.1 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CEG48435.1 - 0.05 13.3 0.2 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEG48435.1 - 0.062 13.7 0.5 8.8 6.8 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEG48435.1 - 0.1 11.6 0.1 7.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.18 CEG48435.1 - 0.19 11.3 0.7 4.8 6.7 0.2 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 CEG48435.1 - 0.38 11.0 2.4 21 5.4 0.1 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 CEG48435.1 - 0.74 8.5 2.0 16 4.1 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Porphobil_deam PF01379.20 CEG48440.1 - 7.2e-67 224.9 0.0 9.5e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CEG48440.1 - 6.4e-16 58.5 0.0 1.6e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Usp PF00582.26 CEG48440.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Utp21 PF04192.12 CEG48441.1 - 1.1e-22 80.7 0.6 1.3e-22 80.5 0.6 1.0 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Nitroreductase PF00881.24 CEG48441.1 - 0.04 14.0 0.0 0.066 13.3 0.0 1.4 1 1 0 1 1 1 0 Nitroreductase family DUF2353 PF09789.9 CEG48446.1 - 7.5e-05 22.2 34.5 0.00078 18.9 34.5 2.6 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Seryl_tRNA_N PF02403.22 CEG48446.1 - 0.005 17.1 6.8 0.005 17.1 6.8 3.5 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF4611 PF15387.6 CEG48446.1 - 0.0064 16.7 4.8 0.053 13.7 4.8 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) SCAB-Ig PF16709.5 CEG48446.1 - 0.083 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein IP_trans PF02121.18 CEG48447.1 - 8.5e-94 313.7 1.7 1e-93 313.5 1.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Hid1 PF12722.7 CEG48448.1 - 5.2e-176 587.2 4.6 1.5e-79 268.2 0.0 3.0 1 1 2 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CEG48448.1 - 2.8e-170 567.8 0.0 2.7e-104 349.8 0.0 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein RhoGAP PF00620.27 CEG48449.1 - 2.8e-16 59.7 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Exo_endo_phos PF03372.23 CEG48449.1 - 1.1e-10 41.4 0.0 2.6e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PX PF00787.24 CEG48450.1 - 8e-30 103.1 0.1 1.2e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CEG48450.1 - 1.4e-11 44.4 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Vps5 C terminal like Peptidase_C1 PF00112.23 CEG48451.1 - 4.3e-56 190.4 0.2 6.6e-56 189.8 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CEG48451.1 - 0.00017 20.5 0.7 0.048 12.4 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 CEG48451.1 - 0.00046 20.6 0.0 0.00096 19.5 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Pkinase PF00069.25 CEG48453.1 - 1.4e-53 182.0 0.0 2.8e-53 181.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48453.1 - 1.5e-27 96.5 0.0 1.2e-26 93.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CEG48453.1 - 2.5e-11 43.9 0.0 5.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.6 CEG48453.1 - 7.3e-06 25.5 0.0 3.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG48453.1 - 0.001 18.5 0.1 0.0025 17.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.6 CEG48454.1 - 6.8e-10 39.0 0.0 3.9e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG48454.1 - 3.2e-08 34.2 0.0 1.5e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 CEG48454.1 - 6.5e-06 25.4 0.0 9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 CEG48454.1 - 1.9e-05 24.1 0.0 0.0003 20.2 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CEG48454.1 - 2e-05 25.2 0.1 0.00023 21.7 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG48454.1 - 0.00012 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEG48454.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 CEG48454.1 - 0.014 14.6 0.0 0.96 8.6 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase Ubie_methyltran PF01209.18 CEG48454.1 - 0.019 14.3 0.0 0.34 10.2 0.0 2.4 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEG48454.1 - 0.044 14.5 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CEG48454.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CEG48454.1 - 0.17 12.9 0.3 1 10.4 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 CEG48454.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_S10 PF00450.22 CEG48455.1 - 5e-124 414.9 0.3 6.4e-124 414.5 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Baculo_LEF-10 PF07206.11 CEG48455.1 - 0.13 12.5 1.3 0.3 11.3 1.3 1.6 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) EF-hand_1 PF00036.32 CEG48456.1 - 2.3e-17 61.2 3.6 7.8e-05 22.0 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CEG48456.1 - 1.9e-15 55.4 1.6 0.00012 21.7 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CEG48456.1 - 1.2e-11 43.5 1.2 0.0059 16.0 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CEG48456.1 - 5.9e-09 36.2 1.8 0.065 13.7 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CEG48456.1 - 8.5e-06 25.5 5.9 0.021 14.6 0.7 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CEG48456.1 - 0.007 16.7 0.1 7.2 7.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain MNE1 PF13762.6 CEG48456.1 - 0.029 14.3 0.3 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Tna_leader PF08053.11 CEG48456.1 - 0.16 12.0 0.2 0.98 9.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophanase operon leader peptide ImmE5 PF11480.8 CEG48458.1 - 0.085 13.4 0.3 1.9 9.1 0.0 2.5 2 0 0 2 2 2 0 Colicin-E5 Imm protein EPV_E5 PF08135.11 CEG48459.1 - 0.00073 19.8 1.0 0.0012 19.1 1.0 1.4 1 0 0 1 1 1 1 Major transforming protein E5 family T_cell_tran_alt PF15128.6 CEG48459.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Nuc_sug_transp PF04142.15 CEG48460.1 - 1.6e-20 73.5 2.6 2.1e-20 73.1 2.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CEG48460.1 - 0.00017 20.9 1.9 0.0002 20.7 1.7 1.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 CEG48460.1 - 0.0021 18.3 2.0 0.0021 18.3 2.0 1.7 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 CEG48460.1 - 0.042 13.1 4.2 0.16 11.2 4.2 2.0 1 1 0 1 1 1 0 UAA transporter family Ank_2 PF12796.7 CEG48461.1 - 2.4e-52 175.5 3.4 3e-16 59.8 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG48461.1 - 6.2e-32 109.6 2.9 1.1e-11 44.9 0.1 4.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG48461.1 - 1.5e-31 108.0 7.2 1.5e-08 34.7 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG48461.1 - 9.6e-30 99.3 4.6 2.9e-06 27.2 0.0 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CEG48461.1 - 5.8e-25 86.6 11.4 2.6e-07 30.8 0.6 5.9 6 0 0 6 6 6 5 Ankyrin repeat RXLR_WY PF18634.1 CEG48463.1 - 0.0054 16.6 0.4 0.11 12.4 0.2 2.4 2 0 0 2 2 2 1 RXLR phytopathogen effector protein WY-domain RRM_1 PF00076.22 CEG48465.1 - 2.4e-19 68.9 0.0 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG48465.1 - 1.4e-09 37.6 0.0 6.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG48465.1 - 1.4e-07 31.3 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 CEG48465.1 - 0.049 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF1866 PF08952.11 CEG48465.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) PHM7_cyt PF14703.6 CEG48465.1 - 0.12 12.6 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter tRNA-synt_1c PF00749.21 CEG48466.1 - 6.8e-96 320.9 0.1 9.5e-96 320.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CEG48466.1 - 3.7e-34 118.1 0.6 1.2e-33 116.5 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L34 PF00468.17 CEG48467.1 - 1.8e-15 56.6 12.6 2.7e-15 56.0 12.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DUF98 PF01947.16 CEG48468.1 - 1.1e-48 165.0 0.0 1.4e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase Cellulase PF00150.18 CEG48469.1 - 4.7e-07 29.5 0.0 7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nucleoporin_FG2 PF15967.5 CEG48470.1 - 2.6e-05 23.0 9.6 2.6e-05 23.0 9.6 3.2 2 1 1 3 3 3 1 Nucleoporin FG repeated region Lzipper-MIP1 PF14389.6 CEG48470.1 - 0.021 15.1 1.3 8.1 6.8 0.1 2.6 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 COG5 PF10392.9 CEG48470.1 - 0.25 11.5 8.2 0.052 13.7 2.5 2.3 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 CEG48470.1 - 0.37 11.2 1.7 15 6.1 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Dynactin_p22 PF07426.11 CEG48470.1 - 0.78 9.6 8.1 1.8 8.4 1.1 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 DUF948 PF06103.11 CEG48470.1 - 0.96 9.7 6.2 7.9 6.8 0.9 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 CEG48470.1 - 1.3 9.3 14.8 67 3.7 14.8 2.5 1 1 0 1 1 1 0 Zinc finger-containing protein Seryl_tRNA_N PF02403.22 CEG48470.1 - 3.4 7.9 11.8 2.9 8.1 7.1 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.13 CEG48470.1 - 3.7 6.1 7.1 0.42 9.2 2.0 1.8 2 0 0 2 2 2 0 Tweety TMF_TATA_bd PF12325.8 CEG48470.1 - 7.6 6.8 10.0 1.8 8.8 1.8 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 CEG48470.1 - 9.3 6.6 8.0 52 4.2 0.1 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain HU-HIG PF18291.1 CEG48472.1 - 0.061 13.4 0.2 0.15 12.2 0.1 1.7 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif MutS_III PF05192.18 CEG48472.1 - 0.5 10.6 4.5 0.5 10.6 2.6 1.7 1 1 0 2 2 2 0 MutS domain III Syntaxin-6_N PF09177.11 CEG48472.1 - 1.3 9.6 7.2 14 6.3 7.2 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YgaB PF14182.6 CEG48472.1 - 3.3 8.2 7.4 2.7 8.4 1.1 2.8 2 1 1 3 3 3 0 YgaB-like protein zf-TFIIB PF13453.6 CEG48473.1 - 0.3 10.5 1.5 0.5 9.7 1.5 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Exo_endo_phos PF03372.23 CEG48479.1 - 5.2e-09 36.0 0.1 9.4e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4231 PF14015.6 CEG48479.1 - 3.4 8.2 5.6 8.7 6.9 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) p450 PF00067.22 CEG48480.1 - 2.9e-71 240.6 3.4 3.6e-71 240.3 3.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribonuclease_3 PF00636.26 CEG48481.1 - 4.4e-07 30.5 0.3 0.00027 21.5 0.0 3.5 3 1 0 3 3 3 2 Ribonuclease III domain Pkinase PF00069.25 CEG48486.1 - 1.1e-66 225.0 0.0 1.9e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CEG48486.1 - 1.2e-57 191.9 0.9 1.2e-17 63.7 0.0 4.8 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CEG48486.1 - 6e-33 114.2 0.0 9.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG48486.1 - 3.1e-05 23.4 0.0 8e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG48486.1 - 9.6e-05 22.4 0.0 0.0041 17.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fcf1 PF04900.12 CEG48487.1 - 9.5e-16 58.0 0.2 2.1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CEG48487.1 - 8e-09 35.8 1.6 1.6e-08 34.8 0.1 2.0 1 1 1 2 2 2 1 PIN like domain Rad21_Rec8_N PF04825.13 CEG48487.1 - 0.0083 16.3 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF3781 PF12636.7 CEG48487.1 - 0.01 15.7 0.3 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Suf PF05843.14 CEG48489.1 - 2.3e-14 54.1 8.7 7.7e-05 22.8 0.1 5.5 3 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEG48489.1 - 1.1e-06 28.9 3.7 8.5 7.5 0.2 7.1 6 1 2 8 8 8 2 Tetratricopeptide repeat HAT PF02184.16 CEG48489.1 - 9.2e-05 22.3 8.7 0.065 13.2 0.0 6.0 6 0 0 6 6 6 2 HAT (Half-A-TPR) repeat TPR_17 PF13431.6 CEG48489.1 - 0.0014 18.9 0.5 16 6.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CEG48489.1 - 0.0027 16.9 9.0 3.3 6.8 0.5 5.0 3 1 0 3 3 3 3 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 CEG48489.1 - 0.041 13.9 12.2 1.6 8.8 2.8 5.9 3 2 1 4 4 4 0 Mad3/BUB1 homology region 1 BOFC_N PF08977.10 CEG48489.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.4 5 0 0 5 5 5 0 Bypass of Forespore C, N terminal ATP-synt_F PF01990.17 CEG48491.1 - 4.3e-32 110.3 0.2 4.9e-32 110.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Arf PF00025.21 CEG48492.1 - 4.5e-79 263.9 0.0 5.3e-79 263.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG48492.1 - 1.4e-14 54.3 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG48492.1 - 8.1e-13 48.3 0.0 9.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEG48492.1 - 1.3e-12 47.6 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEG48492.1 - 6.4e-12 45.3 0.7 6.7e-08 32.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEG48492.1 - 7e-09 35.4 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG48492.1 - 2.9e-05 24.1 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEG48492.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase VWA PF00092.28 CEG48495.1 - 1.7e-11 44.7 0.0 6.1e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CEG48495.1 - 1.5e-06 28.8 0.0 4.4e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 CEG48495.1 - 1.5e-06 26.7 0.7 3.5e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CEG48495.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain zf-RING_2 PF13639.6 CEG48495.1 - 7.6e-06 26.2 4.4 7.6e-06 26.2 4.4 5.7 4 1 1 5 5 5 1 Ring finger domain VWA_3 PF13768.6 CEG48495.1 - 0.00024 21.1 0.0 0.0011 18.9 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CEG48495.1 - 0.0043 16.5 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Dynamin_N PF00350.23 CEG48495.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 CEG48495.1 - 0.1 12.7 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dna2 PF08696.11 CEG48498.1 - 1.3e-55 188.4 0.1 2.7e-55 187.3 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CEG48498.1 - 2.1e-51 174.4 0.2 4.2e-51 173.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEG48498.1 - 1.8e-29 103.3 8.5 7.6e-16 58.7 0.1 3.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CEG48498.1 - 8.4e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEG48498.1 - 4.4e-10 40.1 0.8 1.3e-08 35.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CEG48498.1 - 2.4e-05 24.2 0.9 0.11 12.2 0.0 3.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CEG48498.1 - 0.00063 19.6 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEG48498.1 - 0.032 14.0 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CEG48498.1 - 0.072 13.5 1.2 4.6 7.6 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain Thioredoxin_16 PF18569.1 CEG48498.1 - 0.085 13.0 0.0 4.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin-like domain Adaptin_binding PF10199.9 CEG48498.1 - 0.76 10.4 5.7 0.085 13.5 0.3 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF676 PF05057.14 CEG48499.1 - 2.1e-35 122.2 0.0 2.1e-32 112.4 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CEG48499.1 - 3.3e-06 27.1 0.0 5.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CEG48499.1 - 0.00045 20.1 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CEG48499.1 - 0.003 17.3 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein IQ PF00612.27 CEG48500.1 - 0.0032 17.1 0.1 0.0093 15.7 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2935 PF11155.8 CEG48500.1 - 0.033 14.5 7.5 25 5.2 7.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3683 PF12447.8 CEG48500.1 - 0.25 11.5 0.0 0.25 11.5 0.0 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF3683) ISN1 PF06437.11 CEG48501.1 - 3.4e-94 316.1 0.0 5.1e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase LexA_DNA_bind PF01726.16 CEG48501.1 - 0.074 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Rtf2 PF04641.12 CEG48501.1 - 0.086 12.2 2.9 0.13 11.6 2.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Ras PF00071.22 CEG48502.1 - 6.6e-45 152.6 0.1 8.7e-45 152.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG48502.1 - 1.9e-21 76.5 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG48502.1 - 2.7e-09 36.7 0.1 4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEG48502.1 - 0.00016 21.6 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEG48502.1 - 0.00076 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Omega_Repress PF07764.11 CEG48502.1 - 0.0034 17.9 0.1 0.0064 17.0 0.1 1.4 1 0 0 1 1 1 1 Omega Transcriptional Repressor MMR_HSR1 PF01926.23 CEG48502.1 - 0.0036 17.4 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CEG48502.1 - 0.037 14.3 0.5 25 5.2 0.0 3.6 3 1 0 3 3 3 0 AAA domain SRPRB PF09439.10 CEG48502.1 - 0.044 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit BCDHK_Adom3 PF10436.9 CEG48513.1 - 6.3e-26 91.1 0.0 9.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEG48513.1 - 0.0011 19.5 0.0 0.0027 18.2 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PH PF00169.29 CEG48515.1 - 1.3e-49 167.0 23.2 5.3e-10 39.7 0.3 9.5 7 5 0 7 7 7 7 PH domain PH_8 PF15409.6 CEG48515.1 - 6e-19 68.1 8.8 8.3e-07 29.2 0.3 6.2 6 0 0 6 6 6 4 Pleckstrin homology domain PH_11 PF15413.6 CEG48515.1 - 4.7e-18 65.5 33.6 0.0059 17.0 5.1 9.5 6 4 1 8 8 8 5 Pleckstrin homology domain Par3_HAL_N_term PF12053.8 CEG48515.1 - 0.0095 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PH_9 PF15410.6 CEG48515.1 - 0.01 16.2 5.5 55 4.2 0.0 6.8 6 2 0 6 6 6 0 Pleckstrin homology domain Dpy-30 PF05186.13 CEG48516.1 - 3.4e-05 23.5 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif GXWXG PF14231.6 CEG48516.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 GXWXG protein Tctex-1 PF03645.13 CEG48517.1 - 1.1e-23 83.4 0.2 2.3e-23 82.4 0.2 1.5 1 0 0 1 1 1 1 Tctex-1 family PH PF00169.29 CEG48517.1 - 7.9e-15 55.3 2.9 4.6e-06 27.1 0.1 4.0 4 2 0 4 4 4 2 PH domain PH_11 PF15413.6 CEG48517.1 - 7.7e-08 32.7 1.5 0.0018 18.7 0.1 3.0 1 1 1 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CEG48517.1 - 0.00028 21.1 0.1 0.23 11.7 0.0 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 CEG48517.1 - 0.025 14.9 0.1 14 6.0 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain RasGAP PF00616.19 CEG48517.1 - 0.11 12.3 0.7 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase ACI44 PF15270.6 CEG48519.1 - 0.011 15.9 0.4 0.018 15.3 0.4 1.4 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor DX PF01666.17 CEG48519.1 - 0.055 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 DX module Mannosyl_trans3 PF11051.8 CEG48521.1 - 5.5e-29 101.4 0.0 1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative RNase_J_C PF17770.1 CEG48521.1 - 0.017 16.1 0.1 0.03 15.4 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain Plus-3 PF03126.18 CEG48522.1 - 1.1e-16 61.3 7.1 1.3e-16 61.1 0.0 3.4 3 0 0 3 3 3 1 Plus-3 domain HHH PF00633.23 CEG48522.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HSCB_C PF07743.13 CEG48525.1 - 3.6e-15 56.2 4.8 4.2e-15 56.0 2.4 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CEG48525.1 - 4.5e-07 29.9 0.1 9.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain GIT1_C PF12205.8 CEG48525.1 - 0.13 12.4 1.8 0.55 10.4 0.3 2.5 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4207 PF13904.6 CEG48533.1 - 0.00032 20.5 6.2 0.00032 20.5 6.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4207) ARA70 PF12489.8 CEG48533.1 - 0.61 10.3 7.2 2.3 8.4 0.9 2.8 2 0 0 2 2 2 0 Nuclear coactivator Peptidase_C1_2 PF03051.15 CEG48533.1 - 2 7.1 7.8 0.11 11.3 2.5 1.4 2 0 0 2 2 2 0 Peptidase C1-like family AMP-binding PF00501.28 CEG48534.1 - 2.3e-76 257.1 0.0 4.5e-76 256.1 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CEG48534.1 - 4.4e-07 30.2 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CEG48534.1 - 0.013 16.5 0.1 0.04 14.9 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PDEase_I PF00233.19 CEG48536.1 - 1.1e-55 189.0 4.9 1.4e-55 188.6 4.9 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase LCM PF04072.14 CEG48537.1 - 6.9e-36 124.0 0.0 9.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase HHH_8 PF14716.6 CEG48538.1 - 4.1e-60 200.1 13.7 9.2e-11 42.0 0.0 8.5 8 0 0 8 8 8 8 Helix-hairpin-helix domain TPR_14 PF13428.6 CEG48538.1 - 0.001 19.7 5.5 9.9 7.3 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Arginosuc_synth PF00764.19 CEG48538.1 - 0.0091 15.3 1.5 3.2 7.0 0.0 2.7 3 0 0 3 3 3 2 Arginosuccinate synthase TP_methylase PF00590.20 CEG48538.1 - 8.1 6.3 9.1 2.3 8.1 0.3 3.8 4 0 0 4 4 4 0 Tetrapyrrole (Corrin/Porphyrin) Methylases BSP_II PF05432.11 CEG48539.1 - 1.2 8.7 14.6 1.7 8.3 14.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF87 PF01935.17 CEG48539.1 - 1.9 8.5 5.6 2.5 8.1 5.6 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain CDC45 PF02724.14 CEG48539.1 - 4.2 5.5 12.4 5.3 5.2 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 CEG48539.1 - 5.5 4.0 15.4 5.6 4.0 15.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Bud13 PF09736.9 CEG48539.1 - 5.7 7.3 17.0 12 6.2 17.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex GOLD_2 PF13897.6 CEG48539.1 - 8.5 6.9 7.0 26 5.3 7.0 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Retrotran_gag_2 PF14223.6 CEG48540.1 - 5.7e-28 97.3 3.5 8.3e-28 96.8 3.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CEG48540.1 - 0.00065 19.3 0.5 0.00065 19.3 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 CEG48540.1 - 0.015 15.4 4.2 0.029 14.5 4.2 1.5 1 0 0 1 1 1 0 Zinc knuckle ComFB PF10719.9 CEG48540.1 - 0.036 14.1 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 Late competence development protein ComFB zf-CCHC_5 PF14787.6 CEG48540.1 - 0.068 12.9 1.0 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PhoLip_ATPase_C PF16212.5 CEG48542.1 - 8.5e-07 29.0 2.2 1.1e-06 28.6 2.2 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal KOW PF00467.29 CEG48543.1 - 5.4e-14 51.6 40.0 5.3e-06 26.2 2.5 8.0 8 0 0 8 8 8 4 KOW motif DUF3912 PF13051.6 CEG48543.1 - 0.0081 16.4 4.9 0.15 12.3 0.2 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3912) PUA PF01472.20 CEG48543.1 - 0.12 12.3 1.9 9.1 6.3 0.3 3.1 2 0 0 2 2 2 0 PUA domain YajC PF02699.15 CEG48543.1 - 3.2 7.7 11.5 0.26 11.2 0.3 3.9 4 0 0 4 4 4 0 Preprotein translocase subunit IQ PF00612.27 CEG48544.1 - 3.6e-13 48.0 25.1 6.5e-05 22.4 0.7 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif LRR_4 PF12799.7 CEG48544.1 - 1.3e-06 28.6 2.6 1 9.9 0.0 4.8 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEG48544.1 - 1.5e-05 24.7 16.0 0.056 13.5 0.1 6.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 CEG48544.1 - 0.047 14.2 14.2 26 5.9 0.0 7.2 7 1 0 7 7 7 0 Leucine Rich Repeat DUF3475 PF11961.8 CEG48544.1 - 0.62 10.2 2.8 6.8 6.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3475) ArfGap PF01412.18 CEG48545.1 - 3.3e-24 85.2 0.0 3.3e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PDZ_6 PF17820.1 CEG48545.1 - 7.3e-16 57.8 0.1 7.9e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CEG48545.1 - 1.7e-11 44.3 0.0 4.3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CEG48545.1 - 9.1e-06 25.9 0.1 0.0021 18.3 0.0 2.4 2 0 0 2 2 2 1 PDZ domain zf-dskA_traR PF01258.17 CEG48545.1 - 0.08 12.9 3.1 4.8 7.2 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger GPHH PF16905.5 CEG48545.1 - 0.15 11.8 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated c-SKI_SMAD_bind PF08782.10 CEG48545.1 - 1.7 9.0 5.9 0.28 11.5 0.4 2.5 3 0 0 3 3 3 0 c-SKI Smad4 binding domain Pkinase PF00069.25 CEG48546.1 - 5.1e-13 49.0 0.0 9.8e-12 44.8 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48546.1 - 1.3e-05 24.7 0.0 3.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Brr6_like_C_C PF10104.9 CEG48547.1 - 0.014 15.1 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Hint PF01079.20 CEG48548.1 - 1.7e-19 70.2 0.0 1.3e-15 57.5 0.0 3.3 1 1 0 1 1 1 1 Hint module Kelch_5 PF13854.6 CEG48548.1 - 0.00014 21.8 3.7 0.39 10.8 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Hom_end_hint PF05203.16 CEG48548.1 - 0.00041 20.4 0.1 0.00066 19.7 0.1 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint EGF_2 PF07974.13 CEG48548.1 - 0.00056 20.2 13.4 0.0016 18.7 13.4 1.9 1 0 0 1 1 1 1 EGF-like domain Kelch_1 PF01344.25 CEG48548.1 - 0.0017 17.9 9.0 1.8 8.2 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CEG48548.1 - 0.064 13.6 6.3 4.5 7.7 0.1 3.9 5 0 0 5 5 5 0 Kelch motif CBS PF00571.28 CEG48549.1 - 2.8e-06 27.7 0.2 0.026 14.9 0.1 2.4 2 1 0 2 2 2 2 CBS domain Choline_transpo PF04515.12 CEG48550.1 - 2.8e-75 253.6 18.2 2.8e-75 253.6 18.2 3.8 2 2 2 4 4 4 1 Plasma-membrane choline transporter DUF21 PF01595.20 CEG48550.1 - 7.5e-34 116.9 3.9 7.5e-34 116.9 3.9 3.5 3 1 0 3 3 3 1 Cyclin M transmembrane N-terminal domain Borrelia_P13 PF05628.12 CEG48550.1 - 1.5 8.8 7.9 0.071 13.1 1.3 2.2 2 0 0 2 2 2 0 Borrelia membrane protein P13 Ephrin_rec_like PF07699.13 CEG48551.1 - 1.2e-05 25.0 15.8 1.4e-05 24.8 4.7 60.4 33 14 21 58 58 58 38 Putative ephrin-receptor like PWWP PF00855.17 CEG48552.1 - 2.1e-11 44.1 0.0 7.6e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 CEG48552.1 - 3e-11 43.0 26.8 6.4e-09 35.6 5.4 3.8 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.6 CEG48552.1 - 2.7e-09 37.2 1.8 0.0028 17.9 0.2 2.7 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG48552.1 - 5.4e-07 29.8 0.6 0.022 14.9 0.1 2.7 2 0 0 2 2 2 2 PHD-zinc-finger like domain Bromodomain PF00439.25 CEG48552.1 - 3.4e-06 27.0 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain JIP_LZII PF16471.5 CEG48552.1 - 0.0011 19.1 0.9 0.0034 17.5 0.9 1.8 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II Yuri_gagarin PF15934.5 CEG48552.1 - 0.044 13.6 3.0 0.11 12.3 3.0 1.6 1 0 0 1 1 1 0 Yuri gagarin FANCL_C PF11793.8 CEG48552.1 - 0.056 13.6 9.3 1.7 8.9 2.4 2.9 2 0 0 2 2 2 0 FANCL C-terminal domain HIP1_clath_bdg PF16515.5 CEG48552.1 - 0.06 14.0 2.8 0.36 11.5 2.8 2.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YojJ PF10372.9 CEG48552.1 - 0.06 13.4 0.5 1.8 8.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF641 PF04859.12 CEG48552.1 - 0.16 12.3 2.7 0.56 10.5 2.7 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 CEG48552.1 - 0.35 10.9 2.0 0.89 9.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 CEG48552.1 - 0.66 10.0 7.4 0.23 11.4 1.4 2.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 CEG48552.1 - 0.82 9.5 7.4 0.44 10.4 4.2 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 CEG48552.1 - 1 9.6 7.5 13 6.1 4.6 3.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-PHD-like PF15446.6 CEG48552.1 - 1.7 8.3 16.5 1.6 8.3 2.6 3.4 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Fez1 PF06818.15 CEG48552.1 - 4.9 7.5 7.8 1.6 9.1 2.9 2.5 2 0 0 2 2 2 0 Fez1 CPBP PF02517.16 CEG48553.1 - 1e-12 48.2 17.1 9.3e-11 42.0 17.1 2.9 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease CbiQ PF02361.16 CEG48553.1 - 0.38 10.3 11.8 0.016 14.8 3.4 2.1 2 0 0 2 2 2 0 Cobalt transport protein WD40 PF00400.32 CEG48554.1 - 1.1e-32 111.5 28.3 2.4e-08 34.5 0.5 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48554.1 - 2.1e-16 60.0 1.4 0.00092 19.5 0.2 5.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEG48554.1 - 3.1e-07 30.0 0.0 0.00071 19.0 0.0 3.6 1 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 CEG48554.1 - 0.001 17.8 0.7 1.1 7.9 0.1 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CEG48554.1 - 0.0017 18.0 1.9 0.027 14.1 1.4 2.5 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 CEG48554.1 - 0.025 15.1 7.6 9.5 6.9 0.0 5.1 4 2 1 5 5 5 0 PQQ-like domain Ge1_WD40 PF16529.5 CEG48554.1 - 0.033 13.1 0.1 0.95 8.4 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEG48554.1 - 0.07 12.0 8.8 0.41 9.5 1.1 4.1 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Arena_nucleocap PF00843.17 CEG48554.1 - 0.18 10.7 0.0 0.43 9.4 0.0 1.6 2 0 0 2 2 2 0 Arenavirus nucleocapsid N-terminal domain DUF5111 PF17138.4 CEG48554.1 - 0.18 11.6 1.4 3.5 7.5 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5111) IF4E PF01652.18 CEG48555.1 - 9.7e-54 181.5 0.3 1.3e-53 181.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_L11_N PF03946.14 CEG48555.1 - 4.7e-20 71.2 0.5 1.1e-19 70.0 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DMRL_synthase PF00885.19 CEG48556.1 - 1.5e-14 54.0 0.2 3.1e-14 53.0 0.0 1.5 2 0 0 2 2 2 1 6,7-dimethyl-8-ribityllumazine synthase Chlorosome_CsmC PF11098.8 CEG48557.1 - 0.063 13.3 23.1 0.88 9.5 12.0 2.4 1 1 1 2 2 2 0 Chlorosome envelope protein C Antimicrobial17 PF08129.11 CEG48557.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.6 1 1 1 3 3 3 0 Alpha/beta enterocin family TrbL PF04610.14 CEG48557.1 - 1.7 8.3 8.9 1.1 8.9 4.7 2.0 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Spore_III_AE PF09546.10 CEG48557.1 - 7.7 5.6 5.5 8.9 5.4 2.1 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) Retrotrans_gag PF03732.17 CEG48558.1 - 1.1e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 2 0 0 2 2 2 1 Retrotransposon gag protein AAA_2 PF07724.14 CEG48559.1 - 3.8e-06 27.1 0.4 6.9e-06 26.3 0.4 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TcpQ PF10671.9 CEG48560.1 - 0.00036 20.6 0.1 0.00064 19.8 0.1 1.4 1 0 0 1 1 1 1 Toxin co-regulated pilus biosynthesis protein Q FixH PF05751.11 CEG48561.1 - 2 8.4 6.7 2.4 8.1 0.6 2.8 2 1 1 3 3 3 0 FixH rve PF00665.26 CEG48562.1 - 1.2e-13 51.2 0.0 1.4e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG48562.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Integrase core domain RXLR_WY PF18634.1 CEG48563.1 - 0.00032 20.6 0.8 0.00059 19.7 0.8 1.5 1 0 0 1 1 1 1 RXLR phytopathogen effector protein WY-domain Paxillin PF03535.13 CEG48563.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Paxillin family DASH_Dad2 PF08654.10 CEG48563.1 - 0.015 15.7 0.5 0.033 14.6 0.5 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 HTH_19 PF12844.7 CEG48563.1 - 0.14 12.2 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Snapin_Pallidin PF14712.6 CEG48563.1 - 0.29 11.6 10.8 0.88 10.0 2.6 2.8 3 0 0 3 3 3 0 Snapin/Pallidin Retrotran_gag_2 PF14223.6 CEG48566.1 - 8e-18 64.4 0.1 1.2e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 CEG48566.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Orf78 PF06024.12 CEG48569.1 - 0.056 13.7 0.3 0.062 13.6 0.3 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_M76 PF09768.9 CEG48571.1 - 7.7e-06 25.8 0.2 1.3e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase M76 family MT0933_antitox PF14013.6 CEG48576.1 - 0.11 12.8 10.7 0.27 11.6 10.7 1.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein MMTV_SAg PF01054.17 CEG48579.1 - 0.026 14.1 3.8 0.044 13.3 3.8 1.3 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen UPF0242 PF06785.11 CEG48579.1 - 0.084 13.0 12.9 0.13 12.3 12.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Turandot PF07240.11 CEG48579.1 - 0.097 12.7 0.0 0.4 10.7 0.0 2.0 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Fibin PF15819.5 CEG48579.1 - 0.64 9.7 8.6 0.2 11.4 4.6 1.8 1 1 1 2 2 2 0 Fin bud initiation factor homologue TPR_1 PF00515.28 CEG48580.1 - 1.2e-26 91.3 2.6 5.9e-06 25.9 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CEG48580.1 - 4.4e-23 79.5 0.0 0.00023 21.0 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG48580.1 - 1.9e-10 40.1 0.0 0.0037 17.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG48580.1 - 1.5e-09 38.0 4.1 0.036 14.4 0.0 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEG48580.1 - 1.3e-07 32.0 8.3 0.2 12.2 0.3 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG48580.1 - 4.4e-07 30.2 0.4 0.02 15.7 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48580.1 - 7.1e-07 28.8 0.2 0.38 10.5 0.0 5.0 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 CEG48580.1 - 0.00012 22.7 0.1 2.6 8.8 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 CEG48580.1 - 0.00022 21.3 1.2 0.00059 19.9 0.0 2.3 3 0 0 3 3 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 CEG48580.1 - 0.00028 20.7 1.7 2.9 8.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG48580.1 - 0.00052 20.1 2.5 1.1 9.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG48580.1 - 0.0096 16.2 7.4 15 6.3 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG48580.1 - 0.0097 15.8 0.8 19 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG48580.1 - 0.02 15.1 4.2 0.64 10.3 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG48580.1 - 0.032 14.9 0.2 1.2e+02 3.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MSL2-CXC PF16682.5 CEG48580.1 - 9 6.5 8.4 1.8 8.8 0.8 2.6 3 0 0 3 3 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 TT_ORF2 PF02957.15 CEG48583.1 - 3.8 8.5 5.1 2.1 9.3 0.6 2.0 1 1 1 2 2 2 0 TT viral ORF2 SAPS PF04499.15 CEG48584.1 - 0.014 14.2 20.1 0.021 13.6 20.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 CEG48584.1 - 1.8 7.8 45.9 2 7.7 45.9 1.0 1 0 0 1 1 1 0 BUD22 Raftlin PF15250.6 CEG48584.1 - 5.9 5.5 12.8 7.3 5.2 12.8 1.2 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.25 CEG48585.1 - 6.8e-16 58.4 0.0 7.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48585.1 - 4.4e-12 45.8 0.0 5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG48585.1 - 4.6e-12 45.7 0.0 7.8e-12 45.0 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG48585.1 - 6.6e-09 36.0 0.0 3.7e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CEG48585.1 - 8.2e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 CEG48585.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 CEG48585.1 - 0.022 13.5 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CEG48585.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CEG48585.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ribosomal_L14e PF01929.17 CEG48586.1 - 7e-29 100.1 7.8 1.1e-28 99.5 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CEG48586.1 - 0.0017 18.2 0.7 0.0033 17.3 0.2 1.7 2 0 0 2 2 2 1 KOW motif Ribosomal_L5e PF17144.4 CEG48587.1 - 3.9e-82 274.1 0.9 3.9e-82 274.1 0.9 1.9 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CEG48587.1 - 9.3e-27 93.8 3.8 9.3e-27 93.8 3.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region NusG_add PF18298.1 CEG48587.1 - 0.02 15.1 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 NusG additional domain TrmO_C PF18389.1 CEG48587.1 - 0.083 13.0 0.5 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 TrmO C-terminal domain DUF2040 PF09745.9 CEG48588.1 - 5.1e-32 110.5 14.7 5.1e-32 110.5 14.7 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Homeobox_KN PF05920.11 CEG48589.1 - 2.4e-16 59.4 0.1 6.7e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEG48589.1 - 1.4e-08 34.4 0.1 4.2e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 CEG48591.1 - 1.3e-62 211.6 0.0 2.3e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48591.1 - 6.5e-34 117.4 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 CEG48591.1 - 1.3e-21 76.3 7.9 3.8e-09 36.6 0.7 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48591.1 - 1.8e-21 76.5 1.0 3.4e-17 62.8 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG48591.1 - 6.5e-20 71.2 0.6 4e-11 43.2 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG48591.1 - 6.1e-18 64.4 5.6 1.3e-06 28.5 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CEG48591.1 - 3.1e-15 54.7 1.1 0.00034 20.8 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat PH PF00169.29 CEG48591.1 - 9.2e-12 45.4 0.0 2.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG48591.1 - 0.00033 21.0 0.1 0.0013 19.1 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Csm1_N PF18504.1 CEG48591.1 - 0.009 16.3 0.3 0.028 14.7 0.3 1.8 1 0 0 1 1 1 1 Csm1 N-terminal domain MTS PF05175.14 CEG48593.1 - 2e-10 40.5 0.0 1.4e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 CEG48593.1 - 2e-08 34.0 0.0 4.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CEG48593.1 - 4.5e-08 33.0 0.0 5.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEG48593.1 - 1e-06 29.4 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG48593.1 - 0.00013 22.6 0.0 0.00053 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG48593.1 - 0.00021 21.9 0.0 0.00059 20.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEG48593.1 - 0.0005 19.6 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 CEG48593.1 - 0.0019 18.1 0.0 0.0072 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEG48593.1 - 0.0043 18.1 0.0 0.013 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CEG48593.1 - 0.013 15.1 0.1 0.058 13.1 0.0 2.0 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 DUF43 PF01861.16 CEG48593.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 CEG48593.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 CEG48593.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_33 PF10017.9 CEG48593.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 CEG48593.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Evr1_Alr PF04777.13 CEG48596.1 - 5.5e-15 55.6 0.9 1.5e-14 54.3 0.9 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 CEG48596.1 - 2.5e-14 53.1 0.2 5.1e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CEG48596.1 - 0.0018 17.7 0.2 0.0052 16.2 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CEG48596.1 - 0.0054 16.9 0.4 0.016 15.3 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CEG48596.1 - 0.016 15.5 0.1 0.061 13.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like KRTAP7 PF15034.6 CEG48596.1 - 0.059 14.3 0.4 20 6.2 0.2 2.5 2 0 0 2 2 2 0 KRTAP type 7 family Zn_Tnp_IS1595 PF12760.7 CEG48596.1 - 0.2 11.7 3.8 4 7.5 0.0 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Aminotran_4 PF01063.19 CEG48597.1 - 2.9e-10 40.4 0.1 8.5e-10 38.9 0.1 1.7 1 1 0 1 1 1 1 Amino-transferase class IV Whi5 PF08528.11 CEG48597.1 - 0.17 11.5 1.3 0.31 10.7 1.3 1.5 1 0 0 1 1 1 0 Whi5 like IML1 PF12257.8 CEG48606.1 - 1.1e-87 293.8 0.0 1.6e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 BT1 PF03092.16 CEG48607.1 - 1e-05 24.0 9.0 1e-05 24.0 9.0 2.5 1 1 0 2 2 2 1 BT1 family Acyltransferase PF01553.21 CEG48608.1 - 7.7e-13 48.2 0.1 1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Acyltransferase PBP3 PF18056.1 CEG48608.1 - 0.057 13.5 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain Acyltransf_C PF16076.5 CEG48609.1 - 6.1e-14 51.9 0.1 8.7e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase C-terminus TEX33 PF15400.6 CEG48609.1 - 0.01 16.3 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family WD40 PF00400.32 CEG48611.1 - 1.3e-31 108.1 12.0 7.1e-09 36.2 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48611.1 - 1.4e-18 67.0 0.0 0.00085 19.6 0.0 5.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG48611.1 - 5.3e-08 33.0 0.0 4.6e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CEG48611.1 - 2.9e-05 23.3 0.0 0.13 11.3 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region BBS2_Mid PF14783.6 CEG48611.1 - 5.8e-05 23.1 0.0 0.0047 16.9 0.0 3.2 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CEG48611.1 - 0.00031 20.2 0.0 1.4 8.2 0.0 3.3 3 1 1 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 CEG48611.1 - 0.0011 17.8 0.0 0.39 9.4 0.0 2.3 1 1 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 CEG48611.1 - 0.0018 17.3 0.6 0.47 9.4 0.1 3.1 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG48611.1 - 0.0064 15.2 0.2 1.5 7.4 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CEG48611.1 - 0.029 13.3 0.4 0.053 12.4 0.2 1.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain GSDH PF07995.11 CEG48611.1 - 0.1 11.9 0.0 4 6.7 0.0 2.7 1 1 2 3 3 3 0 Glucose / Sorbosone dehydrogenase Frtz PF11768.8 CEG48611.1 - 0.21 9.9 0.0 8.7 4.5 0.0 2.6 1 1 3 4 4 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 CEG48612.1 - 2.6e-28 99.1 0.0 3.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48612.1 - 2.9e-11 43.2 0.0 4.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Alpha_kinase PF02816.18 CEG48613.1 - 4e-54 183.5 0.0 6.1e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 CEG48613.1 - 1.1e-06 28.1 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 CEG48613.1 - 0.018 15.1 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G DMAP_binding PF06464.11 CEG48613.1 - 0.059 14.2 0.4 0.29 12.0 0.0 2.2 1 1 1 2 2 2 0 DMAP1-binding Domain Glycos_transf_1 PF00534.20 CEG48614.1 - 2.8e-33 114.9 0.0 5.1e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG48614.1 - 3.4e-18 66.4 0.1 1.4e-17 64.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEG48614.1 - 1.7e-13 50.9 0.3 2.7e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CEG48614.1 - 7.9e-06 26.2 0.0 3.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEG48614.1 - 0.00018 22.0 0.0 0.00037 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain RRP7 PF12923.7 CEG48615.1 - 0.028 14.6 0.3 0.035 14.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Pkinase PF00069.25 CEG48617.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain YWFCY PF14293.6 CEG48619.1 - 0.44 10.9 2.0 29 5.1 0.0 3.0 2 1 0 2 2 2 0 YWFCY protein baeRF_family2 PF18844.1 CEG48620.1 - 0.062 13.3 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 SHE3 PF17078.5 CEG48621.1 - 0.0048 16.6 19.4 0.43 10.3 5.4 2.0 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 DUF1759 PF03564.15 CEG48621.1 - 0.011 15.7 7.0 0.43 10.5 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Tup_N PF08581.10 CEG48621.1 - 0.019 15.3 23.8 0.78 10.1 2.3 3.7 2 1 2 4 4 4 0 Tup N-terminal ApoO PF09769.9 CEG48621.1 - 0.032 14.2 2.3 0.068 13.1 0.4 2.3 2 1 1 3 3 3 0 Apolipoprotein O GIT_CC PF16559.5 CEG48621.1 - 0.13 12.1 12.2 0.79 9.6 0.3 3.8 3 2 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3287 PF11690.8 CEG48621.1 - 0.14 11.9 3.7 5.2 6.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) NPV_P10 PF05531.12 CEG48621.1 - 0.15 12.5 12.5 0.28 11.7 0.6 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DASH_Spc19 PF08287.11 CEG48621.1 - 0.18 11.7 18.1 0.43 10.5 1.4 2.3 1 1 1 2 2 2 0 Spc19 TetR_C_37 PF18665.1 CEG48621.1 - 0.2 12.3 5.2 4.1 8.0 0.3 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR PF13972.6 CEG48621.1 - 0.2 11.3 2.5 0.68 9.6 0.2 2.2 2 1 0 2 2 2 0 Bacterial transcriptional repressor FAM184 PF15665.5 CEG48621.1 - 0.21 11.4 23.1 0.12 12.1 12.1 2.1 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B L27_2 PF09045.10 CEG48621.1 - 0.28 11.2 3.1 13 5.9 0.1 3.3 3 1 1 4 4 4 0 L27_2 DUF5624 PF18538.1 CEG48621.1 - 0.29 11.2 1.8 0.57 10.3 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5624) Rx_N PF18052.1 CEG48621.1 - 0.33 11.2 13.9 3.6 7.9 5.4 3.1 1 1 1 2 2 2 0 Rx N-terminal domain HigB-like_toxin PF05015.13 CEG48621.1 - 0.48 10.9 5.2 1.9 9.0 0.5 2.6 2 1 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB FlxA PF14282.6 CEG48621.1 - 0.57 10.2 14.9 0.16 12.0 2.2 2.6 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 CEG48621.1 - 0.79 7.6 14.4 0.96 7.3 14.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AATF-Che1 PF13339.6 CEG48621.1 - 0.86 10.3 14.3 0.28 11.8 5.0 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DASH_Dam1 PF08653.10 CEG48621.1 - 1.3 8.8 9.7 44 4.0 0.0 4.8 4 1 1 5 5 5 0 DASH complex subunit Dam1 MerR-DNA-bind PF09278.11 CEG48621.1 - 1.5 9.4 8.6 37 4.9 0.8 3.9 4 0 0 4 4 4 0 MerR, DNA binding ECM11 PF15463.6 CEG48621.1 - 2.4 8.7 11.5 9 6.9 1.7 2.8 1 1 1 2 2 2 0 Extracellular mutant protein 11 KELK PF15796.5 CEG48621.1 - 2.6 8.5 20.7 0.31 11.5 6.3 2.8 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ran-binding PF05508.11 CEG48621.1 - 2.8 6.8 11.9 0.95 8.4 6.6 2.0 1 1 0 2 2 2 0 RanGTP-binding protein DUF4407 PF14362.6 CEG48621.1 - 4 6.7 13.2 26 4.1 13.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CEG48621.1 - 4 8.1 13.9 4.3 8.0 1.1 4.0 1 1 3 4 4 4 0 SlyX Spc24 PF08286.11 CEG48621.1 - 4.1 7.7 21.5 2.3 8.5 4.7 3.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 CEG48621.1 - 4.7 7.3 17.5 1.2 9.2 1.5 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CEG48621.1 - 5.9 7.2 8.2 9.9 6.5 1.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 CEG48621.1 - 7.6 6.9 17.8 1.5e+04 -3.8 17.8 2.6 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) CD36 PF01130.21 CEG48622.1 - 4.3e-38 131.0 0.0 3.5e-21 75.3 0.0 2.5 2 1 0 2 2 2 2 CD36 family Bac_export_3 PF01313.19 CEG48622.1 - 0.46 10.4 1.8 1.2 9.2 1.8 1.7 1 0 0 1 1 1 0 Bacterial export proteins, family 3 SAM_1 PF00536.30 CEG48623.1 - 3e-14 53.2 0.1 9.6e-14 51.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEG48623.1 - 6.8e-14 51.7 0.0 1.9e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CPBP PF02517.16 CEG48623.1 - 8.3e-10 38.9 15.8 3.8e-09 36.8 15.8 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease IQ PF00612.27 CEG48623.1 - 5.1e-08 32.0 41.6 0.0011 18.6 0.8 6.8 7 0 0 7 7 7 5 IQ calmodulin-binding motif Ank_2 PF12796.7 CEG48623.1 - 7.5e-07 29.7 0.1 2.8e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG48623.1 - 7.5e-05 22.8 0.1 0.016 15.7 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CEG48623.1 - 0.00016 21.9 1.0 0.00063 20.1 1.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CEG48623.1 - 0.00073 20.1 0.2 0.0024 18.4 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG48623.1 - 0.051 13.9 0.3 0.18 12.2 0.3 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF641 PF04859.12 CEG48623.1 - 2.6 8.4 7.3 1.1 9.6 1.9 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Response_reg PF00072.24 CEG48624.1 - 4.5e-10 39.7 0.0 9.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain RNF111_N PF15303.6 CEG48624.1 - 0.085 12.6 2.5 0.2 11.4 2.5 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Crust_neurohorm PF01147.17 CEG48624.1 - 0.15 11.9 0.3 0.4 10.5 0.3 1.7 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family ANAPC4_WD40 PF12894.7 CEG48626.1 - 3.1e-12 46.6 0.0 0.00076 19.7 0.0 7.0 5 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 CEG48626.1 - 1.2e-05 25.1 1.3 2.7e-05 23.9 1.3 1.6 1 0 0 1 1 1 1 Synaptobrevin Lgl_C PF08596.10 CEG48626.1 - 0.00012 21.0 4.0 0.00064 18.5 0.1 3.5 4 1 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 CEG48626.1 - 0.00072 20.3 7.6 13 6.9 0.0 7.1 7 0 0 7 7 7 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 CEG48626.1 - 0.0008 18.8 0.1 0.24 10.6 0.0 3.4 3 1 1 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PDZ_6 PF17820.1 CEG48626.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 CEG48626.1 - 0.088 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 PDZ domain RVT_3 PF13456.6 CEG48627.1 - 2.9e-26 91.7 0.1 3.5e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 CEG48627.1 - 1e-11 45.2 0.5 4.6e-11 43.1 0.5 1.8 1 1 0 1 1 1 1 RNase H P2_N PF18628.1 CEG48627.1 - 0.066 13.0 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain DUF4952 PF16310.5 CEG48627.1 - 0.084 13.1 0.6 0.72 10.1 0.1 2.2 1 1 1 2 2 2 0 Domian of unknown function (DUF4952) Ste5_C PF12194.8 CEG48627.1 - 0.091 12.7 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein kinase Fus3-binding MbtH PF03621.13 CEG48627.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 MbtH-like protein Cyt-b5 PF00173.28 CEG48628.1 - 5.7e-26 90.5 0.0 2.3e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF1892 PF08987.10 CEG48628.1 - 0.0077 16.4 0.2 0.87 9.8 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1892) Gpi16 PF04113.14 CEG48629.1 - 5.4e-108 361.8 1.2 4.2e-106 355.6 1.2 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component cobW PF02492.19 CEG48630.1 - 1.9e-32 112.3 0.0 2.5e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CEG48630.1 - 0.0027 16.7 0.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CEG48630.1 - 0.0035 17.4 0.0 0.0086 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEG48630.1 - 0.0044 17.4 0.0 0.0071 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CEG48630.1 - 0.013 16.0 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CEG48630.1 - 0.04 14.0 0.0 0.29 11.2 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 CEG48630.1 - 0.051 13.6 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mito_fiss_Elm1 PF06258.11 CEG48630.1 - 0.054 12.6 0.0 0.094 11.8 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial fission ELM1 TIP49 PF06068.13 CEG48630.1 - 0.056 12.7 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CEG48630.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 CEG48630.1 - 0.093 12.7 0.0 0.23 11.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 CEG48630.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 CEG48630.1 - 0.17 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CEG48630.1 - 0.2 12.1 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PAS PF00989.25 CEG48633.1 - 2.3e-209 681.5 10.4 5.6e-21 74.6 0.0 11.3 11 0 0 11 11 11 11 PAS fold PAS_4 PF08448.10 CEG48633.1 - 2.4e-138 452.7 0.0 3.6e-13 49.7 0.0 11.3 11 0 0 11 11 11 11 PAS fold PAS_9 PF13426.7 CEG48633.1 - 1.2e-122 401.4 28.6 6.5e-12 45.6 0.1 11.3 11 0 0 11 11 11 11 PAS domain PAS_3 PF08447.12 CEG48633.1 - 1.1e-69 230.8 0.0 2.8e-05 24.3 0.0 11.3 11 0 0 11 11 11 11 PAS fold PAS_8 PF13188.7 CEG48633.1 - 1e-32 111.6 8.2 0.055 13.5 0.0 10.6 10 0 0 10 10 10 8 PAS domain HATPase_c PF02518.26 CEG48633.1 - 1.7e-25 89.7 0.0 6.2e-25 87.9 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 CEG48633.1 - 2.1e-25 89.4 14.7 0.0027 18.3 0.0 11.0 11 0 0 11 11 11 6 PAS domain Response_reg PF00072.24 CEG48633.1 - 1.6e-19 70.1 0.0 4.5e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CEG48633.1 - 1.8e-16 59.9 0.0 4.8e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 CEG48633.1 - 1.7e-07 31.4 1.0 7.9e-07 29.3 1.0 2.2 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 CEG48633.1 - 2.2e-06 27.8 30.4 1.1 9.5 0.1 12.6 11 9 0 11 11 11 2 PAS fold sCache_3_3 PF17202.4 CEG48633.1 - 8.2e-06 26.2 13.2 87 3.6 0.0 10.2 10 0 0 10 10 10 0 Single cache domain 3 DUF3189 PF11385.8 CEG48633.1 - 0.00033 20.5 0.2 9.5 6.1 0.0 5.2 5 0 0 5 5 4 1 Protein of unknown function (DUF3189) UPF0180 PF03698.13 CEG48633.1 - 0.074 13.2 0.0 27 5.0 0.0 3.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) HATPase_c_3 PF13589.6 CEG48633.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DRTGG PF07085.12 CEG48633.1 - 0.13 12.1 0.0 3.5e+02 1.0 0.0 5.7 9 0 0 9 9 9 0 DRTGG domain DUF5588 PF17826.1 CEG48633.1 - 0.38 9.6 7.9 13 4.6 0.0 5.8 8 0 0 8 8 8 0 Family of unknown function (DUF5588) PGAP1 PF07819.13 CEG48634.1 - 0.0022 17.8 0.0 0.0059 16.4 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CEG48634.1 - 0.05 13.1 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RVT_2 PF07727.14 CEG48636.1 - 3.6e-11 43.2 0.0 3.9e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transgly PF00912.22 CEG48636.1 - 0.061 12.8 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase Retrotran_gag_2 PF14223.6 CEG48637.1 - 1.2e-09 38.0 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Enkurin PF13864.6 CEG48637.1 - 0.11 13.0 0.1 0.25 11.8 0.1 1.4 1 1 0 1 1 1 0 Calmodulin-binding CsoSCA PF08936.10 CEG48638.1 - 0.054 12.2 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Glucan_synthase PF02364.15 CEG48640.1 - 3e-185 617.8 16.1 3.2e-165 551.6 10.1 2.5 1 1 1 2 2 2 2 1,3-beta-glucan synthase component Sugar_tr PF00083.24 CEG48640.1 - 3.3e-29 102.1 29.3 3.3e-29 102.1 29.3 3.6 2 1 0 3 3 3 2 Sugar (and other) transporter FKS1_dom1 PF14288.6 CEG48640.1 - 1.3e-23 83.7 1.5 7.3e-23 81.3 1.5 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MFS_1 PF07690.16 CEG48640.1 - 1.1e-12 47.5 35.2 1.1e-12 47.5 35.2 5.4 3 1 2 5 5 5 1 Major Facilitator Superfamily CcmE PF03100.15 CEG48640.1 - 0.13 12.3 0.1 0.84 9.6 0.1 2.5 2 0 0 2 2 2 0 CcmE DUF4083 PF13314.6 CEG48641.1 - 0.26 11.3 1.7 2.6 8.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) T3SS_needle_E PF08988.10 CEG48642.1 - 0.0014 18.8 0.4 0.0034 17.5 0.1 1.8 2 0 0 2 2 2 1 Type III secretion system, cytoplasmic E component of needle DUF677 PF05055.12 CEG48643.1 - 0.001 18.1 0.4 0.0011 18.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Prefoldin_2 PF01920.20 CEG48643.1 - 0.0018 18.2 1.0 0.0022 18.0 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit NBD94 PF16830.5 CEG48643.1 - 0.051 14.0 0.4 0.063 13.7 0.4 1.1 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Acyltransferase PF01553.21 CEG48644.1 - 3.8e-06 26.6 0.0 0.091 12.4 0.0 2.8 2 1 1 3 3 3 2 Acyltransferase FA_desaturase PF00487.24 CEG48644.1 - 0.017 15.0 1.6 0.017 15.0 1.6 1.7 2 0 0 2 2 2 0 Fatty acid desaturase ROK PF00480.20 CEG48645.1 - 3.6e-58 197.4 1.2 4.3e-58 197.1 1.2 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 CEG48645.1 - 7.5e-05 22.4 0.0 0.00017 21.2 0.1 1.6 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 CEG48645.1 - 0.00029 20.5 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Paf1 PF03985.13 CEG48646.1 - 1.9e-65 221.6 6.8 1.9e-65 221.6 6.8 1.8 2 1 0 2 2 2 1 Paf1 Hormone_3 PF00159.18 CEG48646.1 - 0.13 12.4 0.2 0.4 10.8 0.2 1.9 1 0 0 1 1 1 0 Pancreatic hormone peptide MRP-L28 PF09812.9 CEG48646.1 - 0.2 11.8 5.5 0.049 13.8 1.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Ank_4 PF13637.6 CEG48647.1 - 1e-22 80.2 0.2 4.1e-07 30.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48647.1 - 2.5e-16 60.0 0.0 5.6e-07 30.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CEG48647.1 - 5.6e-16 58.2 1.3 0.00025 21.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEG48647.1 - 4.3e-13 49.2 0.1 0.0065 16.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG48647.1 - 6.7e-12 44.5 0.0 0.0065 16.9 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeat HECT PF00632.25 CEG48648.1 - 4.8e-68 229.9 0.2 6.1e-68 229.6 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DOMON PF03351.17 CEG48648.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 DOMON domain zf-RanBP PF00641.18 CEG48648.1 - 3.6 7.0 11.5 0.022 14.1 2.2 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PX PF00787.24 CEG48649.1 - 2.9e-05 24.0 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SAP PF02037.27 CEG48649.1 - 0.063 13.0 0.3 0.063 13.0 0.3 1.7 2 0 0 2 2 2 0 SAP domain Adaptin_N PF01602.20 CEG48651.1 - 1.8e-89 300.7 1.0 2.4e-89 300.3 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 CEG48651.1 - 1.9e-27 95.5 0.0 4.5e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 CEG48651.1 - 1.3e-10 41.6 0.1 1.3e-09 38.3 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEG48651.1 - 0.00063 20.1 1.9 0.14 12.6 0.1 3.7 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CEG48651.1 - 0.00071 20.0 1.6 5.9 7.5 0.0 3.9 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 CEG48651.1 - 0.045 14.0 0.3 0.81 10.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat WD40 PF00400.32 CEG48652.1 - 9e-20 70.7 5.4 5.2e-06 27.1 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48652.1 - 3.1e-14 53.1 0.0 0.06 13.6 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CEG48652.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 CEG48652.1 - 0.072 12.0 0.1 5.4 5.9 0.0 2.9 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEG48652.1 - 0.18 11.7 0.0 3.5 7.5 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A EcKinase PF02958.20 CEG48653.1 - 2.2e-15 56.8 0.1 6.5e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 CEG48653.1 - 7.2e-13 48.2 0.0 1.5e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 CEG48653.1 - 6.8e-10 39.3 0.1 9.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG48653.1 - 0.0026 17.2 0.1 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CEG48653.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SusE PF14292.6 CEG48653.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.7 2 0 0 2 2 2 0 SusE outer membrane protein PC4 PF02229.16 CEG48655.1 - 1.7e-43 146.0 1.3 2.4e-21 75.1 0.3 2.3 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) CorA PF01544.18 CEG48655.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SRF-TF PF00319.18 CEG48656.1 - 3.8e-24 83.9 0.3 8.4e-24 82.8 0.3 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UQ_con PF00179.26 CEG48657.1 - 1.2e-18 67.1 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG48657.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 RWD domain GatB_N PF02934.15 CEG48658.1 - 1.1e-86 290.6 0.0 2.5e-86 289.5 0.0 1.6 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CEG48658.1 - 2.2e-38 131.5 0.0 3.6e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 GatB domain Abhydrolase_6 PF12697.7 CEG48659.1 - 5.5e-14 53.3 0.0 6.4e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEG48659.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG48659.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold PH PF00169.29 CEG48660.1 - 3.5e-09 37.1 0.1 9.4e-08 32.5 0.0 2.7 2 1 0 2 2 2 1 PH domain RabGAP-TBC PF00566.18 CEG48660.1 - 9.3e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_11 PF15413.6 CEG48660.1 - 0.0049 17.3 0.1 0.015 15.7 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG48660.1 - 0.049 13.9 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Nop52 PF05997.12 CEG48661.1 - 1.8e-61 207.7 8.2 1.8e-61 207.7 8.2 2.5 3 0 0 3 3 3 1 Nucleolar protein,Nop52 Rootletin PF15035.6 CEG48664.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 CEG48664.1 - 0.17 11.9 1.7 0.37 10.8 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 CEG48664.1 - 0.21 11.1 5.9 0.83 9.1 0.9 2.1 1 1 1 2 2 2 0 Leucine zipper BRE1 PF08647.11 CEG48664.1 - 0.3 11.2 3.8 0.093 12.8 0.7 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Ku_C PF03730.14 CEG48664.1 - 2.4 8.9 8.2 4 8.2 0.2 3.1 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm NACHT PF05729.12 CEG48665.1 - 2.4e-07 30.9 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CEG48665.1 - 7e-05 23.3 0.0 0.00025 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG48665.1 - 0.015 15.6 0.0 0.052 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 CEG48666.1 - 8.3e-06 25.2 5.6 0.0052 16.5 1.5 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif PH PF00169.29 CEG48667.1 - 5.4e-10 39.7 0.0 2.7e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF5089 PF17002.5 CEG48667.1 - 0.0095 15.8 0.9 0.088 12.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF5089) Med13_N PF11597.8 CEG48667.1 - 0.048 13.0 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal SNARE PF05739.19 CEG48667.1 - 0.071 13.1 0.3 6.1 6.9 0.1 3.2 3 0 0 3 3 3 0 SNARE domain Tropomyosin PF00261.20 CEG48667.1 - 0.15 11.4 4.6 0.29 10.5 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin Complex1_LYR PF05347.15 CEG48668.1 - 1.1e-10 41.4 1.0 2.3e-10 40.4 1.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEG48668.1 - 6.5e-07 30.0 0.5 6.5e-07 30.0 0.5 1.6 1 1 0 1 1 1 1 Complex1_LYR-like DUF2096 PF09869.9 CEG48668.1 - 0.0074 16.4 0.1 0.0093 16.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) Complex1_LYR_1 PF13232.6 CEG48668.1 - 0.022 15.4 0.4 0.032 14.8 0.4 1.6 1 1 0 1 1 1 0 Complex1_LYR-like MbeB_N PF04837.12 CEG48668.1 - 0.062 13.6 0.3 12 6.2 0.1 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pyr_redox_2 PF07992.14 CEG48670.1 - 2.8e-50 171.2 0.1 3.9e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG48670.1 - 7.5e-23 80.9 0.0 5.5e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEG48670.1 - 7.4e-17 61.7 1.4 2.6e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEG48670.1 - 9.4e-13 48.1 0.5 6.6e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEG48670.1 - 4.7e-07 29.2 2.1 1.1e-06 28.0 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CEG48670.1 - 1.1e-05 24.9 0.0 0.07 12.4 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CEG48670.1 - 0.0038 16.4 0.3 0.02 14.0 0.6 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CEG48670.1 - 0.0051 16.1 1.3 0.028 13.7 0.2 2.6 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 CEG48670.1 - 0.0059 15.4 0.5 0.016 13.9 0.1 1.9 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 CEG48670.1 - 0.017 14.5 1.0 0.062 12.6 0.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 CEG48670.1 - 0.02 14.5 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEG48670.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.5 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain gpW PF02831.15 CEG48672.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 gpW UTP15_C PF09384.10 CEG48673.1 - 1.7e-45 154.3 0.1 2.6e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CEG48673.1 - 1.2e-20 73.4 17.2 2e-05 25.3 0.2 6.6 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48673.1 - 1.1e-06 28.9 0.0 0.016 15.5 0.0 3.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG48673.1 - 0.01 14.5 1.3 5 5.6 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CEG48673.1 - 0.13 11.6 0.0 15 4.8 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain CSN8_PSD8_EIF3K PF10075.9 CEG48674.1 - 1.3e-13 51.1 0.9 1.6e-13 50.9 0.1 1.5 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CEG48674.1 - 0.017 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 PCI domain DcpS PF05652.12 CEG48674.1 - 0.2 12.5 1.8 0.35 11.7 0.2 2.0 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal NIF PF03031.18 CEG48676.1 - 1.5e-23 83.3 0.1 3.3e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Propeptide_C25 PF08126.11 CEG48676.1 - 0.073 12.2 0.3 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Propeptide_C25 GDP_Man_Dehyd PF16363.5 CEG48677.1 - 8.9e-58 196.3 0.0 2.8e-57 194.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEG48677.1 - 8.5e-53 179.3 0.0 1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEG48677.1 - 1.4e-19 70.2 0.0 1.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEG48677.1 - 4.8e-18 65.3 0.0 4e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEG48677.1 - 1.2e-13 50.8 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CEG48677.1 - 1.4e-07 31.0 0.0 3e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CEG48677.1 - 5.7e-05 23.1 0.0 0.00021 21.2 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CEG48677.1 - 0.00044 19.8 0.0 0.0024 17.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CEG48677.1 - 0.017 15.0 0.1 0.062 13.2 0.1 1.8 1 1 0 1 1 1 0 KR domain DUF1953 PF09196.10 CEG48677.1 - 0.045 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) UDPG_MGDP_dh_N PF03721.14 CEG48677.1 - 0.049 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 CEG48677.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FYVE PF01363.21 CEG48679.1 - 1.3e-13 50.9 9.5 3e-13 49.7 9.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger DHR10 PF18595.1 CEG48679.1 - 0.03 14.4 5.6 0.079 13.0 5.6 1.7 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TcpS PF17456.2 CEG48679.1 - 0.061 13.4 0.3 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S FYVE_2 PF02318.16 CEG48679.1 - 0.3 11.3 5.1 1 9.6 5.1 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger CLZ PF16526.5 CEG48679.1 - 0.39 11.1 2.3 1.3 9.5 2.3 1.9 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2203 PF09969.9 CEG48679.1 - 0.98 10.2 3.8 51 4.6 1.5 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) T3SSipB PF16535.5 CEG48679.1 - 1.9 8.9 6.3 15 6.0 0.4 2.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB C1_2 PF03107.16 CEG48679.1 - 2.3 8.6 8.0 0.85 10.0 4.5 2.1 2 0 0 2 2 2 0 C1 domain DUF3395 PF11875.8 CEG48680.1 - 1e-25 90.5 0.5 1.9e-25 89.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CEG48680.1 - 9.9e-13 48.0 0.1 2.1e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4286 PF14114.6 CEG48680.1 - 0.14 12.7 0.6 0.89 10.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) MORN PF02493.20 CEG48681.1 - 5.7e-38 126.6 76.3 8.8e-06 25.3 0.1 10.2 10 0 0 10 10 10 9 MORN repeat VasL PF12486.8 CEG48681.1 - 0.0008 19.3 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Type VI secretion system, EvfB, or VasL DUF276 PF03434.13 CEG48681.1 - 0.012 14.8 0.2 0.027 13.7 0.1 1.5 2 0 0 2 2 2 0 DUF276 DUF5342 PF17277.2 CEG48681.1 - 0.053 13.9 9.1 0.16 12.3 0.1 3.8 4 1 0 4 4 4 0 Family of unknown function (DUF5342) DUF747 PF05346.11 CEG48682.1 - 4.8e-95 318.7 21.4 6e-95 318.4 21.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PUF PF00806.19 CEG48683.1 - 1.8e-46 153.3 11.1 7.6e-06 25.3 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH_4 PF18044.1 CEG48683.1 - 7.7e-07 28.8 6.7 1.7e-06 27.6 6.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEG48683.1 - 0.00022 21.2 6.6 0.00043 20.2 6.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEG48683.1 - 0.0026 17.6 6.7 0.0053 16.7 6.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEG48683.1 - 0.005 17.5 0.5 0.013 16.2 0.5 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CEG48683.1 - 1.8 9.1 11.4 0.93 10.1 6.3 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Bundlin PF05307.11 CEG48693.1 - 0.29 11.0 4.7 0.42 10.5 4.7 1.2 1 0 0 1 1 1 0 Bundlin DUF563 PF04577.14 CEG48694.1 - 2.1e-23 83.5 0.1 3.7e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RT_RNaseH_2 PF17919.1 CEG48695.1 - 1.3e-30 105.3 0.0 1.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEG48695.1 - 1.4e-19 70.3 0.0 1.8e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_GPA PF05840.13 CEG48697.1 - 3.7e-68 230.0 0.2 8.6e-68 228.8 0.2 1.6 1 1 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) gpD PF02925.16 CEG48698.1 - 2e-98 326.0 1.7 2.3e-98 325.8 1.7 1.0 1 0 0 1 1 1 1 Bacteriophage scaffolding protein D Phage_F PF02305.17 CEG48699.1 - 1.4e-162 542.0 1.0 7.2e-89 298.9 0.4 2.0 1 1 1 2 2 2 2 Capsid protein (F protein) KNOX2 PF03791.13 CEG48699.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain Phage_G PF02306.15 CEG48700.1 - 8.8e-125 413.0 3.2 9.8e-125 412.9 3.2 1.0 1 0 0 1 1 1 1 Major spike protein (G protein) Microvir_H PF04687.12 CEG48701.1 - 5.4e-217 719.1 22.3 6.1e-217 719.0 22.3 1.0 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) Ppx-GppA PF02541.16 CEG48703.1 - 8.7e-20 71.3 0.0 9.4e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Dimer_Tnp_hAT PF05699.14 CEG48705.1 - 2.1e-06 27.4 0.2 4.5e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region adh_short PF00106.25 CEG48707.1 - 2.9e-21 75.8 0.0 1.3e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEG48707.1 - 1.6e-15 57.3 0.0 5.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Spt4 PF06093.13 CEG48707.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.7 4 0 0 4 4 4 0 Spt4/RpoE2 zinc finger AIG2_2 PF13772.6 CEG48710.1 - 0.062 13.7 0.0 0.078 13.4 0.0 1.1 1 0 0 1 1 1 0 AIG2-like family PAN_1 PF00024.26 CEG48712.1 - 0.043 13.8 0.2 0.18 11.8 0.2 2.0 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 CEG48712.1 - 0.058 13.5 0.9 0.21 11.7 0.9 2.0 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.12 CEG48712.1 - 4.7 7.1 6.4 1.7 8.5 1.9 2.3 2 0 0 2 2 2 0 PAN-like domain GlcNAc PF11397.8 CEG48713.1 - 3.7e-43 148.3 0.0 1.4e-35 123.4 0.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) FAM220 PF15487.6 CEG48713.1 - 0.0054 16.4 0.8 0.14 11.8 0.1 2.6 3 0 0 3 3 3 1 FAM220 family Nuc_sug_transp PF04142.15 CEG48714.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Nucleotide-sugar transporter GlcNAc PF11397.8 CEG48715.1 - 3.5e-35 122.1 2.1 8e-15 55.1 1.3 3.5 1 1 2 3 3 3 3 Glycosyltransferase (GlcNAc) Ntox28 PF15605.6 CEG48716.1 - 0.019 15.2 6.8 0.021 15.0 1.4 3.0 2 1 0 2 2 2 0 Bacterial toxin 28 PA_decarbox PF05870.11 CEG48720.1 - 2.9e-09 36.7 0.4 4.2e-09 36.2 0.4 1.3 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Thioredoxin PF00085.20 CEG48721.1 - 6.5e-08 32.5 0.4 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Gal4_dimer PF03902.13 CEG48721.1 - 0.054 13.7 0.5 0.2 11.8 0.5 2.0 1 0 0 1 1 1 0 Gal4-like dimerisation domain Prismane PF03063.20 CEG48721.1 - 0.54 8.9 2.8 0.66 8.6 2.8 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF3801 PF12687.7 CEG48721.1 - 2 8.5 13.7 0.8 9.8 10.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Alpha_kinase PF02816.18 CEG48722.1 - 4e-51 173.7 0.0 5.6e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 CEG48722.1 - 8.4e-05 22.2 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 Short C-terminal domain C1-set PF07654.15 CEG48722.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin C1-set domain DMAP_binding PF06464.11 CEG48722.1 - 0.17 12.7 1.0 0.49 11.2 0.1 2.2 2 0 0 2 2 2 0 DMAP1-binding Domain Pkinase PF00069.25 CEG48725.1 - 6.1e-65 219.2 0.0 8.3e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48725.1 - 3.1e-33 115.2 0.0 4.2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CEG48725.1 - 2.7e-08 34.3 0.1 8.1e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CEG48725.1 - 2.9e-05 23.5 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEG48725.1 - 0.0023 17.9 0.5 0.0037 17.2 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG48725.1 - 0.011 14.6 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PH_11 PF15413.6 CEG48725.1 - 0.025 15.0 0.2 0.11 13.0 0.2 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_C PF00433.24 CEG48725.1 - 0.38 11.5 6.9 0.051 14.3 1.0 2.8 2 0 0 2 2 2 0 Protein kinase C terminal domain TPR_1 PF00515.28 CEG48726.1 - 6.5e-05 22.6 11.4 0.0027 17.4 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG48726.1 - 8.9e-05 22.3 9.3 0.00034 20.5 0.6 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48726.1 - 0.00022 20.9 0.7 0.15 11.7 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 CEG48726.1 - 0.00058 20.1 1.0 0.019 15.2 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEG48726.1 - 0.023 14.8 3.6 0.16 12.1 0.2 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CEG48726.1 - 0.027 15.3 3.9 5.6 8.1 0.0 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG48726.1 - 0.053 13.4 1.8 0.49 10.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RsbRD_N PF14361.6 CEG48726.1 - 0.1 13.3 0.1 0.1 13.3 0.1 2.8 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain FRB_dom PF08771.11 CEG48726.1 - 0.32 11.4 5.1 0.092 13.2 0.5 2.5 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain TPR_8 PF13181.6 CEG48726.1 - 3.7 8.0 7.6 0.49 10.7 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40_3 PF15911.5 CEG48727.1 - 2.4e-17 62.7 0.0 6.4e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48727.1 - 9.3e-11 41.9 0.1 0.0016 18.7 0.1 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CEG48727.1 - 4.6e-06 26.6 4.7 0.42 10.5 0.1 4.6 2 1 1 4 4 4 2 Region in Clathrin and VPS IKI3 PF04762.12 CEG48727.1 - 0.0011 17.1 0.0 0.038 12.0 0.0 2.5 3 0 0 3 3 3 1 IKI3 family eIF2A PF08662.11 CEG48727.1 - 0.0024 17.8 0.0 0.9 9.4 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CEG48727.1 - 0.0033 18.2 3.8 0.5 11.3 0.1 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat TPR_7 PF13176.6 CEG48727.1 - 0.0036 17.2 16.5 24 5.2 0.0 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CEG48727.1 - 0.0085 15.2 7.9 0.43 9.6 0.0 4.7 4 1 1 5 5 5 1 Coatomer WD associated region Frtz PF11768.8 CEG48727.1 - 0.13 10.6 0.0 6.2 5.0 0.0 3.4 4 1 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_12 PF13424.6 CEG48727.1 - 0.38 11.1 30.3 0.49 10.7 0.2 7.2 5 2 0 6 6 6 0 Tetratricopeptide repeat NAD_kinase PF01513.21 CEG48730.1 - 6.3e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase His_Phos_1 PF00300.22 CEG48730.1 - 1.6e-13 50.8 0.3 3.5e-13 49.7 0.3 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DAGK_cat PF00781.24 CEG48730.1 - 0.0091 15.6 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF2120 PF09893.9 CEG48730.1 - 0.028 14.5 0.1 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) WW PF00397.26 CEG48731.1 - 3.5e-13 49.4 1.8 8.9e-07 28.9 0.6 2.7 2 0 0 2 2 2 2 WW domain FF PF01846.19 CEG48731.1 - 9.4e-10 38.5 0.1 1.7e-07 31.3 0.0 3.2 3 0 0 3 3 3 1 FF domain Glyco_hyd_101C PF17451.2 CEG48731.1 - 0.077 13.3 5.5 8.5 6.7 0.2 3.7 3 1 1 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain MMR1 PF08505.10 CEG48732.1 - 0.24 11.6 11.6 0.29 11.4 11.6 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4164 PF13747.6 CEG48732.1 - 0.31 11.4 20.2 1.9 8.8 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Pkinase PF00069.25 CEG48734.1 - 1.2e-61 208.4 0.0 6.7e-42 143.7 0.3 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48734.1 - 2.6e-30 105.6 0.2 1.3e-25 90.2 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG48734.1 - 0.00098 18.2 0.7 0.0016 17.5 0.7 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEG48734.1 - 0.036 13.7 0.7 0.062 12.9 0.7 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CEG48734.1 - 0.096 12.0 0.1 0.37 10.0 0.0 1.9 1 1 1 2 2 2 0 Kinase-like CLASP_N PF12348.8 CEG48735.1 - 6.6e-18 65.1 16.3 5.1e-16 58.9 2.7 5.5 5 0 0 5 5 5 2 CLASP N terminal HEAT_2 PF13646.6 CEG48735.1 - 1.8e-08 34.7 8.3 0.28 11.6 0.1 7.6 7 2 1 8 8 8 2 HEAT repeats HEAT PF02985.22 CEG48735.1 - 3.7e-05 23.6 18.0 2.4 8.6 0.1 9.9 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CEG48735.1 - 0.00017 22.1 3.8 24 5.6 0.0 6.5 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEG48735.1 - 0.74 10.4 12.8 26 5.5 0.0 7.6 10 0 0 10 10 10 0 HEAT-like repeat End3 PF12761.7 CEG48737.1 - 0.022 14.9 10.3 0.22 11.7 6.1 2.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Imm64 PF15600.6 CEG48737.1 - 0.057 13.1 0.8 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 Immunity protein 64 Nnf1 PF03980.14 CEG48737.1 - 0.099 13.0 0.4 0.099 13.0 0.4 2.8 2 1 0 2 2 2 0 Nnf1 YabA PF06156.13 CEG48737.1 - 0.31 11.7 6.6 0.12 13.1 1.7 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Rootletin PF15035.6 CEG48737.1 - 0.38 10.8 7.8 1.1 9.3 7.3 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 CEG48737.1 - 1.1 9.4 7.6 0.35 10.9 3.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CdvA PF18822.1 CEG48737.1 - 1.6 8.6 6.8 0.48 10.3 2.3 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF1157 PF06636.11 CEG48742.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) CTP_transf_like PF01467.26 CEG48747.1 - 1.8e-08 34.7 0.0 6.6e-08 32.9 0.0 2.0 2 1 0 2 2 2 1 Cytidylyltransferase-like Nitro_FeMo-Co PF02579.17 CEG48747.1 - 0.022 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Proteasome PF00227.26 CEG48748.1 - 5e-57 192.5 0.2 6.7e-57 192.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEG48748.1 - 6.8e-14 51.2 0.1 1.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 CEG48748.1 - 0.0079 16.6 0.5 0.0079 16.6 0.5 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3842) Synaptobrevin PF00957.21 CEG48749.1 - 2e-24 85.2 3.2 3.6e-24 84.4 3.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEG48749.1 - 3.8e-16 58.9 0.2 6.1e-16 58.2 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain GP41 PF00517.17 CEG48749.1 - 0.025 14.5 3.0 0.081 12.8 3.0 1.7 1 1 0 1 1 1 0 Retroviral envelope protein Cas_DxTHG PF09455.10 CEG48749.1 - 0.07 12.7 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Borrelia_P13 PF05628.12 CEG48749.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Borrelia membrane protein P13 Ost4 PF10215.9 CEG48752.1 - 0.0031 17.3 0.1 0.0042 16.9 0.1 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase T4-Gluco-transf PF09198.10 CEG48752.1 - 0.026 14.1 0.8 0.6 9.8 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Death PF00531.22 CEG48752.1 - 0.086 13.0 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Death domain NAM PF02365.15 CEG48755.1 - 0.14 13.1 0.0 0.15 13.0 0.0 1.2 1 0 0 1 1 1 0 No apical meristem (NAM) protein gag_pre-integrs PF13976.6 CEG48756.1 - 1.5e-08 34.3 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Orbi_VP2 PF00898.17 CEG48760.1 - 0.43 8.3 2.2 0.5 8.1 2.2 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 rve PF00665.26 CEG48761.1 - 1.1e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEG48761.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease PH PF00169.29 CEG48763.1 - 5.7e-24 84.7 0.1 9.6e-11 42.1 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 CEG48763.1 - 2.4e-12 46.9 3.5 1.2e-07 31.9 0.1 2.8 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 CEG48763.1 - 3.7e-11 43.4 8.6 0.00071 20.0 0.3 4.2 2 2 1 3 3 3 2 Pleckstrin homology domain Methyltransf_23 PF13489.6 CEG48763.1 - 0.054 13.3 0.0 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain PH_9 PF15410.6 CEG48763.1 - 0.072 13.5 0.4 33 4.9 0.0 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain PrgU PF09627.10 CEG48763.1 - 0.094 12.7 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 PrgU-like protein Alpha-2-MRAP_C PF06401.11 CEG48764.1 - 0.012 15.6 0.9 0.024 14.6 0.9 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain ISET-FN3_linker PF16625.5 CEG48764.1 - 0.099 13.2 0.4 0.2 12.2 0.4 1.5 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO RVT_1 PF00078.27 CEG48765.1 - 0.25 10.8 0.0 0.41 10.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) COG6 PF06419.11 CEG48766.1 - 2.2e-130 435.8 1.1 1.2e-129 433.4 0.8 1.9 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 ATG16 PF08614.11 CEG48766.1 - 0.76 10.0 7.4 1.7 8.8 7.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CEG48766.1 - 0.88 9.6 3.6 2.1 8.4 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HTH_ParB PF17762.1 CEG48767.1 - 0.085 12.7 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 HTH domain found in ParB protein Mito_carr PF00153.27 CEG48773.1 - 1.7e-48 162.5 0.3 6.6e-19 67.6 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.29 CEG48773.1 - 2.7e-34 117.1 0.0 9.1e-20 70.5 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Peptidase_C92 PF05708.12 CEG48773.1 - 0.017 15.2 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family SecE PF00584.20 CEG48776.1 - 4.5e-14 52.1 0.0 5.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4926 PF16277.5 CEG48777.1 - 0.17 11.2 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) Amidase PF01425.21 CEG48779.1 - 1.8e-121 406.3 0.3 1.9e-92 310.6 0.1 2.0 1 1 1 2 2 2 2 Amidase Thioredoxin PF00085.20 CEG48780.1 - 1.5e-17 63.5 0.2 2.8e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 CEG48780.1 - 3.2e-10 40.4 0.0 8.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Erv1 / Alr family OST3_OST6 PF04756.13 CEG48780.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CEG48780.1 - 0.00078 19.6 0.4 0.022 14.9 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG48780.1 - 0.018 15.5 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEG48780.1 - 0.1 12.9 0.5 0.45 10.9 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin-like Patched PF02460.18 CEG48782.1 - 6.1e-57 193.3 11.6 4.5e-44 150.7 1.4 3.2 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.8 CEG48782.1 - 1.1e-32 113.0 10.0 1.1e-32 113.0 10.0 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 CEG48782.1 - 1e-06 28.5 2.8 2.3e-06 27.4 2.8 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus MMPL PF03176.15 CEG48782.1 - 8.7 5.2 16.6 0.061 12.2 2.9 3.4 4 1 0 4 4 4 0 MMPL family IMS PF00817.20 CEG48784.1 - 1.1e-45 155.3 0.0 2e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 CEG48784.1 - 1.5e-06 27.7 1.7 3.3e-06 26.6 1.7 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 CEG48784.1 - 0.00028 21.6 0.0 0.0014 19.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEG48784.1 - 0.009 16.3 0.1 0.023 15.0 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif Fic PF02661.18 CEG48787.1 - 0.011 16.6 0.2 0.25 12.2 0.2 2.1 1 1 0 1 1 1 0 Fic/DOC family Carboxyl_trans PF01039.22 CEG48788.1 - 2.1e-189 630.3 0.1 2.5e-189 630.0 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CEG48788.1 - 0.02 14.4 0.1 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) SIS PF01380.22 CEG48789.1 - 1.3e-33 115.6 2.1 2.6e-17 62.9 0.0 3.2 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CEG48789.1 - 3.8e-08 33.6 0.2 0.0043 17.2 0.2 2.5 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_7 PF13537.6 CEG48789.1 - 1.4e-05 25.0 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain RPA_interact_C PF14768.6 CEG48791.1 - 0.12 12.9 1.8 0.39 11.3 1.8 1.8 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF2335 PF10097.9 CEG48791.1 - 0.77 9.8 3.7 10 6.2 0.2 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) COG5 PF10392.9 CEG48791.1 - 1.5 9.0 6.8 1.1 9.5 1.4 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Retrotran_gag_2 PF14223.6 CEG48793.1 - 2.9e-08 33.5 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DNA_gyraseB PF00204.25 CEG48793.1 - 0.039 13.4 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase B SWI2_SNF2 PF18766.1 CEG48794.1 - 4.5e-27 95.2 1.3 1.1e-26 93.9 1.3 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 CEG48794.1 - 1.6e-17 64.1 1.8 1.6e-17 64.1 1.8 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WW PF00397.26 CEG48794.1 - 1e-07 31.9 0.4 1.8e-07 31.1 0.4 1.5 1 0 0 1 1 1 1 WW domain DEAD PF00270.29 CEG48794.1 - 1.6e-07 31.3 4.3 6.9e-07 29.2 4.3 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CEG48794.1 - 0.011 16.1 2.3 0.067 13.5 2.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG48794.1 - 0.033 14.5 0.5 0.54 10.5 0.5 2.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CEG48794.1 - 0.054 13.6 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DENN PF02141.21 CEG48796.1 - 3.2e-27 95.7 2.5 6.3e-27 94.7 2.5 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CEG48796.1 - 0.0087 16.8 0.0 0.025 15.3 0.0 1.8 1 0 0 1 1 1 1 uDENN domain SPAR_C PF11881.8 CEG48796.1 - 0.044 13.7 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 C-terminal domain of SPAR protein Flot PF15975.5 CEG48797.1 - 0.046 13.9 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 Flotillin DUF3195 PF11424.8 CEG48797.1 - 0.083 13.0 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Uds1 PF15456.6 CEG48800.1 - 0.013 15.6 2.8 0.013 15.6 2.8 2.0 2 0 0 2 2 2 0 Up-regulated During Septation TLE_N PF03920.15 CEG48800.1 - 0.029 14.5 0.8 0.055 13.5 0.1 1.8 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Trimer_CC PF08954.11 CEG48800.1 - 0.056 13.0 2.4 0.27 10.8 2.4 2.2 1 0 0 1 1 1 0 Trimerisation motif ABC_tran_CTD PF16326.5 CEG48800.1 - 0.084 13.1 2.2 14 6.0 0.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF3138 PF11336.8 CEG48800.1 - 0.18 10.3 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4140 PF13600.6 CEG48800.1 - 0.19 12.2 2.0 0.67 10.4 0.6 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3573 PF12097.8 CEG48800.1 - 0.2 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SlyX PF04102.12 CEG48800.1 - 0.2 12.3 2.2 0.76 10.4 2.2 2.0 1 0 0 1 1 1 0 SlyX Gon7 PF08738.10 CEG48800.1 - 0.31 11.2 5.3 0.066 13.3 1.1 2.1 2 0 0 2 2 2 0 Gon7 family DivIC PF04977.15 CEG48800.1 - 0.83 9.5 6.4 0.15 11.8 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 CEG48800.1 - 1.5 9.1 7.5 2.3 8.4 0.7 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CCDC-167 PF15188.6 CEG48800.1 - 6.5 7.2 8.0 0.35 11.2 0.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Annexin PF00191.20 CEG48804.1 - 3e-52 174.5 4.0 8.7e-15 54.6 0.1 4.3 4 0 0 4 4 4 4 Annexin Phage_fiber PF03335.13 CEG48804.1 - 1.9 8.9 9.2 2.2 8.7 0.2 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat IlvN PF07991.12 CEG48805.1 - 0.078 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF773 PF05600.12 CEG48806.1 - 6.2e-127 424.4 9.7 7.3e-127 424.2 9.7 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 HMMR_N PF15905.5 CEG48806.1 - 0.016 14.7 1.3 0.016 14.7 1.3 2.6 3 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal SWIRM PF04433.17 CEG48806.1 - 0.02 15.2 0.4 0.27 11.6 0.1 2.9 2 0 0 2 2 2 0 SWIRM domain HR1 PF02185.16 CEG48806.1 - 0.2 11.8 3.5 0.65 10.1 0.1 3.1 2 0 0 2 2 2 0 Hr1 repeat Peptidase_U32_C PF16325.5 CEG48806.1 - 0.26 11.6 3.9 6.7 7.1 0.0 3.6 4 0 0 4 4 4 0 Peptidase family U32 C-terminal domain YabA PF06156.13 CEG48806.1 - 0.35 11.5 3.3 32 5.3 0.1 3.6 4 1 0 4 4 4 0 Initiation control protein YabA Fib_alpha PF08702.10 CEG48806.1 - 0.62 10.3 5.9 1 9.5 1.9 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Annexin PF00191.20 CEG48807.1 - 9.7e-53 176.1 0.2 2.1e-15 56.5 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF3848 PF12959.7 CEG48807.1 - 0.032 14.3 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Annexin PF00191.20 CEG48808.1 - 2.4e-42 142.8 0.2 1e-11 44.7 0.0 4.3 4 0 0 4 4 4 4 Annexin HALZ PF02183.18 CEG48809.1 - 0.29 11.4 6.3 0.4 10.9 0.7 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Peptidase_C2 PF00648.21 CEG48810.1 - 0.04 12.9 0.0 0.04 12.9 0.0 1.0 1 0 0 1 1 1 0 Calpain family cysteine protease SNARE PF05739.19 CEG48810.1 - 0.58 10.2 4.2 3.7 7.6 0.3 2.1 1 1 1 2 2 2 0 SNARE domain Hexapep PF00132.24 CEG48811.1 - 2.8e-29 99.7 30.3 1.6e-08 34.0 2.6 5.4 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEG48811.1 - 2.3e-13 49.6 27.9 6e-05 22.7 3.0 6.2 4 2 2 6 6 6 5 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CEG48811.1 - 0.072 12.0 1.6 0.36 9.7 0.1 2.2 2 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 CEG48811.1 - 0.93 7.5 9.1 1.7 6.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) FYVE PF01363.21 CEG48812.1 - 5.9e-06 26.3 10.9 1.5e-05 25.1 10.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG48812.1 - 0.0035 17.5 10.5 0.0093 16.2 10.5 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 CEG48812.1 - 2.5 8.3 11.6 7.1 6.9 11.6 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger zf-TAZ PF02135.16 CEG48814.1 - 9.3e-15 54.9 18.0 3.9e-09 36.8 9.5 2.4 2 0 0 2 2 2 2 TAZ zinc finger SAGA-Tad1 PF12767.7 CEG48814.1 - 2.3e-06 27.5 0.3 2.3e-06 27.5 0.3 2.6 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Rieske PF00355.26 CEG48815.1 - 3.3e-09 36.6 0.1 5.9e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CEG48815.1 - 1.3e-07 31.5 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Citrate_synt PF00285.21 CEG48816.1 - 0.00046 19.4 0.1 0.0007 18.8 0.1 1.4 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5336 PF17270.2 CEG48816.1 - 0.018 14.7 0.8 0.035 13.7 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Zip PF02535.22 CEG48817.1 - 9.8e-27 94.0 13.0 2.7e-26 92.6 13.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2721 PF11026.8 CEG48817.1 - 0.97 9.3 13.7 0.21 11.5 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Phage_prot_Gp6 PF05133.14 CEG48819.1 - 0.12 11.5 0.1 0.13 11.3 0.1 1.0 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like RXLR PF16810.5 CEG48822.1 - 0.00018 21.9 2.9 9.2 6.7 0.0 4.2 4 0 0 4 4 4 3 RXLR phytopathogen effector protein, Avirulence activity Glycos_transf_1 PF00534.20 CEG48830.1 - 0.00031 20.3 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG48830.1 - 0.0015 19.0 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mannosyl_trans3 PF11051.8 CEG48831.1 - 6.6e-23 81.4 0.0 1.1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative AAA_16 PF13191.6 CEG48833.1 - 0.1 12.9 0.6 0.19 12.1 0.6 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CEG48833.1 - 0.12 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mannosyl_trans3 PF11051.8 CEG48834.1 - 9e-35 120.4 0.1 8.7e-34 117.1 0.1 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 CEG48835.1 - 8.7e-23 80.8 27.2 8.7e-23 80.8 27.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CEG48835.1 - 5e-05 22.3 8.7 0.0006 18.8 0.1 3.1 1 1 2 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 CEG48835.1 - 0.0021 17.0 14.8 0.0021 17.0 14.8 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3925 PF13063.6 CEG48835.1 - 0.055 13.7 0.9 8.5 6.7 0.9 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3925) PH PF00169.29 CEG48836.1 - 4.1e-64 213.7 9.3 5e-10 39.8 0.1 11.9 11 0 0 11 11 11 11 PH domain PH_11 PF15413.6 CEG48836.1 - 1.2e-14 54.6 15.9 0.0015 18.9 0.2 10.3 11 1 0 11 11 11 4 Pleckstrin homology domain PH_9 PF15410.6 CEG48836.1 - 2.9e-07 30.9 18.2 0.34 11.3 0.0 10.2 10 3 0 10 10 10 3 Pleckstrin homology domain PH_2 PF08458.10 CEG48836.1 - 0.013 15.8 13.3 3.3 8.1 0.1 7.1 8 0 0 8 8 8 0 Plant pleckstrin homology-like region PH_8 PF15409.6 CEG48836.1 - 0.033 14.5 10.2 9.3 6.6 0.0 7.0 8 0 0 8 8 8 0 Pleckstrin homology domain DUF2344 PF10105.9 CEG48836.1 - 0.76 9.6 3.8 2.9 7.7 3.8 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) C2 PF00168.30 CEG48838.1 - 9.5e-11 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 CEG48839.1 - 8.9e-10 38.9 11.8 0.026 14.9 0.0 7.1 6 1 0 6 6 6 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG48839.1 - 4.4e-07 29.3 8.9 0.019 14.9 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 CEG48839.1 - 2e-05 23.8 9.3 0.0014 18.1 0.6 5.0 6 0 0 6 6 6 2 EF hand DUF1722 PF08349.11 CEG48839.1 - 0.004 17.4 2.4 2.1 8.7 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1722) EF-hand_5 PF13202.6 CEG48839.1 - 0.13 11.8 1.1 8.7 6.0 0.1 2.9 2 0 0 2 2 2 0 EF hand NiFe_hyd_SSU_C PF14720.6 CEG48840.1 - 0.04 14.3 0.1 0.045 14.1 0.1 1.1 1 0 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal GCP_N_terminal PF17681.1 CEG48842.1 - 0.04 13.5 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal OTCace_N PF02729.21 CEG48843.1 - 0.082 12.9 0.0 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain WD40 PF00400.32 CEG48844.1 - 5.1e-11 42.9 20.3 0.002 18.9 3.2 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG48844.1 - 0.0052 17.0 0.2 0.58 10.5 0.1 4.4 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 CEG48844.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 HELP motif HPS3_N PF14761.6 CEG48844.1 - 0.044 13.3 2.2 18 4.8 0.0 4.4 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 Ribosomal_L1 PF00687.21 CEG48846.1 - 2.2e-52 177.8 0.0 2.9e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ISET-FN3_linker PF16625.5 CEG48846.1 - 0.099 13.2 0.3 0.23 12.0 0.3 1.6 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO P2 PF07194.11 CEG48846.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 P2 response regulator binding domain BPL_LplA_LipB PF03099.19 CEG48847.1 - 7.3e-19 68.0 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CEG48847.1 - 4.8e-05 23.2 0.1 8.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain AAA PF00004.29 CEG48848.1 - 1.6e-37 128.9 0.0 2.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG48848.1 - 8.7e-09 35.0 0.0 2.7e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CEG48848.1 - 9.5e-08 31.9 0.2 9.5e-08 31.9 0.2 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CEG48848.1 - 0.00014 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CEG48848.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG48848.1 - 0.00021 21.3 0.0 0.00096 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEG48848.1 - 0.0023 18.1 0.4 0.0059 16.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CEG48848.1 - 0.0024 17.3 0.1 0.0062 15.9 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEG48848.1 - 0.0036 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 CEG48848.1 - 0.016 15.5 0.4 0.12 12.6 0.1 2.5 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CEG48848.1 - 0.018 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CEG48848.1 - 0.02 15.3 0.0 0.057 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 CEG48848.1 - 0.031 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 CEG48848.1 - 0.049 12.8 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain His_kinase PF06580.13 CEG48848.1 - 0.05 13.9 2.3 0.1 13.0 0.1 2.4 3 0 0 3 3 2 0 Histidine kinase AAA_14 PF13173.6 CEG48848.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEG48848.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 CEG48848.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CEG48848.1 - 0.087 12.3 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CEG48848.1 - 0.089 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CEG48848.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEG48848.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase YlzJ PF14035.6 CEG48849.1 - 0.069 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 YlzJ-like protein Diphthamide_syn PF01866.17 CEG48851.1 - 2.5e-115 385.1 0.0 2.9e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.25 CEG48852.1 - 1.8e-71 240.6 0.0 2.3e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48852.1 - 4e-34 118.1 0.0 5.9e-34 117.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG48852.1 - 0.0026 17.1 0.3 0.0067 15.8 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG48852.1 - 0.0049 16.2 0.2 0.27 10.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CEG48852.1 - 0.018 14.7 0.4 0.43 10.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 CEG48852.1 - 0.045 12.6 0.0 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 CEG48852.1 - 0.068 12.1 0.1 0.12 11.3 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CEG48852.1 - 0.16 11.8 0.6 1 9.2 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EIF_2_alpha PF07541.12 CEG48855.1 - 1.2e-41 141.5 0.6 1.2e-41 141.5 0.6 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CEG48855.1 - 2.7e-15 56.4 0.4 8.2e-15 54.9 0.4 1.8 1 0 0 1 1 1 1 S1 RNA binding domain E1_UFD PF09358.10 CEG48855.1 - 0.055 14.2 1.3 1.1 10.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin fold domain Halo_GVPC PF05465.13 CEG48855.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat MazG-like PF12643.7 CEG48856.1 - 4.1e-15 55.8 0.0 9.8e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 CEG48856.1 - 4.3e-06 26.8 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TrbL PF04610.14 CEG48857.1 - 0.26 11.0 3.2 0.46 10.2 3.2 1.3 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein CCDC53 PF10152.9 CEG48857.1 - 3.1 8.2 11.6 0.32 11.4 6.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Cnn_1N PF07989.11 CEG48857.1 - 6.5 7.0 14.5 10 6.3 0.5 3.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CotH PF08757.11 CEG48858.1 - 2.3e-33 116.1 0.5 2.6e-32 112.6 0.5 2.0 1 1 0 1 1 1 1 CotH kinase protein EGF_2 PF07974.13 CEG48858.1 - 0.15 12.5 5.4 0.38 11.2 5.4 1.7 1 0 0 1 1 1 0 EGF-like domain ABC_tran PF00005.27 CEG48859.1 - 2.9e-30 105.6 0.7 5.7e-20 72.2 0.3 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG48859.1 - 1.5e-19 71.0 2.4 2.1e-05 24.5 0.8 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG48859.1 - 4e-15 55.9 0.2 2.6e-10 40.1 0.2 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEG48859.1 - 4.2e-06 27.1 1.2 0.13 12.5 0.8 3.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEG48859.1 - 1.8e-05 24.9 0.8 0.17 12.0 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG48859.1 - 7.2e-05 23.2 1.4 0.13 12.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 CEG48859.1 - 0.00015 21.7 6.3 0.1 12.5 0.6 3.7 3 2 1 4 4 4 2 NACHT domain SRP54 PF00448.22 CEG48859.1 - 0.00017 21.3 0.0 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CEG48859.1 - 0.00019 21.2 0.0 0.14 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CEG48859.1 - 0.00024 21.0 0.0 0.73 9.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEG48859.1 - 0.00031 20.4 0.0 0.092 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEG48859.1 - 0.00041 20.3 0.0 0.15 12.0 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 CEG48859.1 - 0.00048 20.7 0.1 0.18 12.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG48859.1 - 0.00073 19.2 2.6 0.037 13.6 0.5 2.6 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEG48859.1 - 0.0012 19.4 0.1 1.4 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CEG48859.1 - 0.0025 17.6 0.4 0.88 9.3 0.0 3.0 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CEG48859.1 - 0.0027 18.1 0.1 0.81 10.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 CEG48859.1 - 0.0035 17.0 0.1 6.3 6.4 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEG48859.1 - 0.0039 17.3 1.6 0.066 13.3 0.0 3.2 5 0 0 5 5 4 1 Helicase HerA, central domain SbcCD_C PF13558.6 CEG48859.1 - 0.0041 17.3 0.1 7.9 6.8 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 CEG48859.1 - 0.0058 16.8 0.1 2.2 8.5 0.1 2.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CEG48859.1 - 0.0087 16.5 0.6 1.2 9.5 0.2 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CEG48859.1 - 0.011 16.2 0.3 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CEG48859.1 - 0.011 14.7 0.0 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 CEG48859.1 - 0.015 15.3 2.5 9.5 6.2 0.1 3.5 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CEG48859.1 - 0.028 14.4 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CEG48859.1 - 0.043 13.7 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CEG48859.1 - 0.049 13.9 0.0 4.8 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEG48859.1 - 0.052 13.1 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 CEG48859.1 - 0.087 12.5 0.1 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 CEG48859.1 - 0.088 12.5 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain RIG-I_C PF18119.1 CEG48859.1 - 0.11 12.6 0.7 2.1 8.4 0.2 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Aldedh PF00171.22 CEG48860.1 - 2.5e-156 520.8 0.8 2.5e-154 514.2 0.8 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF2114 PF09887.9 CEG48860.1 - 0.047 12.2 0.2 0.2 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2114) DUF1487 PF07368.11 CEG48860.1 - 0.096 12.1 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF4156 PF13698.6 CEG48861.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Aldedh PF00171.22 CEG48863.1 - 2.7e-39 135.0 0.0 3.7e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNase_T PF00929.24 CEG48864.1 - 5.5e-08 33.5 0.0 2.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Exonuclease Hus1 PF04005.12 CEG48865.1 - 3.5e-44 151.1 0.2 3.9e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Trypsin PF00089.26 CEG48866.1 - 3e-05 24.0 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG48866.1 - 0.047 14.6 0.2 0.11 13.4 0.0 1.7 2 0 0 2 2 2 0 Trypsin-like peptidase domain Autophagy_C PF10381.9 CEG48866.1 - 0.21 11.2 1.6 0.49 10.0 1.6 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Med4 PF10018.9 CEG48867.1 - 0.0028 17.4 13.6 0.0028 17.4 13.6 3.1 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.11 CEG48867.1 - 0.0054 15.6 27.4 0.013 14.4 27.4 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein MIP-T3_C PF17749.1 CEG48867.1 - 8 6.4 29.6 0.19 11.7 21.0 2.7 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region RVT_2 PF07727.14 CEG48868.1 - 3.1e-33 115.4 0.0 3.7e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 CEG48868.1 - 0.046 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlororespiratory reduction 6 p450 PF00067.22 CEG48870.1 - 8.6e-69 232.5 1.6 8.6e-69 232.5 1.6 1.4 2 0 0 2 2 2 1 Cytochrome P450 DUF2384 PF09722.10 CEG48870.1 - 0.19 11.8 0.1 0.51 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) XRCC1_N PF01834.16 CEG48871.1 - 7.8e-05 22.7 0.2 0.00012 22.1 0.2 1.3 1 0 0 1 1 1 1 XRCC1 N terminal domain Stealth_CR1 PF17101.5 CEG48871.1 - 0.63 9.8 1.6 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 EF-hand_4 PF12763.7 CEG48872.1 - 0.00015 21.7 0.0 0.00047 20.1 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Cnl2_NKP2 PF09447.10 CEG48872.1 - 0.11 12.7 0.6 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 Cnl2/NKP2 family protein BAG PF02179.16 CEG48873.1 - 5.2e-08 33.2 0.8 5.2e-08 33.2 0.8 2.1 2 1 0 2 2 2 1 BAG domain SDA1 PF05285.12 CEG48873.1 - 0.17 11.2 9.0 0.31 10.4 9.0 1.4 1 0 0 1 1 1 0 SDA1 TRAPP PF04051.16 CEG48875.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Pterin_bind PF00809.22 CEG48876.1 - 0.074 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Pterin binding enzyme Syntaxin-6_N PF09177.11 CEG48876.1 - 0.4 11.3 4.8 4.7 7.8 0.9 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FYVE PF01363.21 CEG48877.1 - 1.4e-09 38.0 9.6 2.9e-09 36.9 9.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG48877.1 - 0.032 14.4 6.2 0.09 13.0 6.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4576 PF15144.6 CEG48877.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Ank PF00023.30 CEG48878.1 - 1.5e-10 41.1 0.2 0.00017 21.9 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CEG48878.1 - 2.7e-10 40.6 1.1 7e-08 32.9 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG48878.1 - 3.8e-10 39.8 0.9 2.5e-06 27.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48878.1 - 1.5e-08 35.1 0.1 2.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG48878.1 - 2.9e-05 24.1 0.1 0.0024 18.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat RWP-RK PF02042.15 CEG48879.1 - 4.8e-20 71.3 0.1 8.3e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain ATP-grasp_5 PF13549.6 CEG48883.1 - 0.24 10.8 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain 5_3_exonuc_N PF02739.16 CEG48884.1 - 7e-12 45.5 0.2 7e-12 45.5 0.2 1.0 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain mRNA_decap_C PF16741.5 CEG48884.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Pkinase PF00069.25 CEG48885.1 - 1.8e-47 162.0 0.0 2.1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48885.1 - 1e-22 80.7 0.0 1.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG48885.1 - 7.8e-12 45.1 0.0 1.1e-07 31.5 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CEG48885.1 - 9.6e-05 22.4 0.1 0.004 17.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Novirhabdo_Nv PF05554.11 CEG48885.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein COX5A PF02284.16 CEG48885.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Pox_ser-thr_kin PF05445.11 CEG48885.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RRM_1 PF00076.22 CEG48886.1 - 0.0034 17.2 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 CEG48886.1 - 0.0055 16.0 9.5 0.057 12.8 3.6 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf_C2HC_14 PF18574.1 CEG48886.1 - 0.052 13.3 1.5 0.052 13.3 1.5 1.9 2 0 0 2 2 2 0 C2HC Zing finger domain HypA PF01155.19 CEG48886.1 - 0.39 10.8 6.8 2.1 8.4 3.7 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cript PF10235.9 CEG48886.1 - 0.69 10.5 9.0 6.1 7.5 2.7 2.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF2125 PF09898.9 CEG48888.1 - 0.031 13.9 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) ATG2_CAD PF13329.6 CEG48888.1 - 0.082 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF743 PF05332.11 CEG48888.1 - 0.22 11.6 3.8 0.51 10.4 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF743) cNMP_binding PF00027.29 CEG48890.1 - 0.00045 20.2 0.0 0.0044 17.1 0.0 2.3 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Porin_3 PF01459.22 CEG48891.1 - 1.7e-41 142.5 9.0 2e-41 142.2 9.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CS PF04969.16 CEG48892.1 - 4e-16 59.8 0.0 7.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CEG48892.1 - 2.7e-15 56.1 0.1 5.9e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. TMEM51 PF15345.6 CEG48892.1 - 0.05 13.5 1.8 0.11 12.3 1.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1943 PF09172.11 CEG48892.1 - 0.056 12.7 4.0 0.085 12.1 3.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) HA2 PF04408.23 CEG48892.1 - 0.2 11.9 1.7 0.18 12.1 0.2 1.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) Fe-S_biosyn PF01521.20 CEG48894.1 - 1.1e-17 64.3 0.0 1.5e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase_fungal PF17667.1 CEG48898.1 - 0.0087 14.9 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEG48898.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SBF2 PF12335.8 CEG48900.1 - 0.0035 17.0 0.3 0.0035 17.0 0.3 2.0 2 0 0 2 2 2 1 Myotubularin protein Alanine_zipper PF11839.8 CEG48900.1 - 0.093 13.1 3.4 0.35 11.3 3.4 2.0 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein SNARE PF05739.19 CEG48900.1 - 0.85 9.7 5.5 2.5 8.2 0.4 2.9 2 0 0 2 2 2 0 SNARE domain SPC22 PF04573.12 CEG48901.1 - 1.3e-53 181.0 1.1 1.4e-53 180.9 1.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Formyl_trans_N PF00551.19 CEG48903.1 - 4.6e-24 85.1 0.0 6.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CEG48903.1 - 4.8e-10 39.6 0.0 8.2e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain VPS9 PF02204.18 CEG48905.1 - 2.6e-16 59.7 0.1 5.8e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 CEG48905.1 - 6.7e-14 52.3 0.0 1.7e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG48905.1 - 0.00091 19.6 0.9 0.0034 17.8 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 CEG48905.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pex24p PF06398.11 CEG48905.1 - 0.012 14.7 6.5 0.026 13.5 6.5 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Abhydrolase_3 PF07859.13 CEG48907.1 - 7.3e-17 61.9 0.9 2.6e-16 60.1 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CEG48907.1 - 1.5e-15 57.1 1.7 6.3e-15 55.0 1.6 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CEG48907.1 - 1.2e-07 32.6 0.1 1.9e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CEG48907.1 - 6.1e-05 22.6 0.1 0.0081 15.6 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CEG48907.1 - 0.0015 17.5 0.0 0.0032 16.4 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 CEG48907.1 - 0.0047 16.5 0.1 0.19 11.2 0.0 3.1 4 0 0 4 4 4 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 CEG48907.1 - 0.011 15.4 0.1 0.066 12.8 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG48907.1 - 0.013 14.7 0.5 0.11 11.7 0.2 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 RepB PF07506.11 CEG48907.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein Lipase PF00151.19 CEG48907.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipase FAM176 PF14851.6 CEG48908.1 - 0.081 12.6 0.6 0.13 11.9 0.3 1.5 1 1 1 2 2 2 0 FAM176 family DUF4366 PF14283.6 CEG48908.1 - 0.19 11.8 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) COMMD1_N PF17221.3 CEG48910.1 - 0.12 12.6 0.0 0.15 12.4 0.0 1.0 1 0 0 1 1 1 0 COMMD1 N-terminal domain Ank_4 PF13637.6 CEG48911.1 - 1.2e-11 44.9 0.3 1.5e-06 28.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEG48911.1 - 1.9e-08 34.8 0.1 3e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG48911.1 - 3e-06 27.2 0.6 0.0049 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEG48911.1 - 0.0017 18.6 0.3 0.0092 16.3 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG48911.1 - 0.002 18.5 0.6 3.2 8.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat CDC27 PF09507.10 CEG48914.1 - 2.5e-06 27.2 29.1 1.3e-05 24.8 27.9 2.0 1 1 1 2 2 2 1 DNA polymerase subunit Cdc27 TIP49 PF06068.13 CEG48915.1 - 1.5e-158 527.6 1.2 2.1e-158 527.1 1.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEG48915.1 - 2.2e-25 88.6 0.9 6.3e-25 87.1 0.9 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CEG48915.1 - 2.2e-09 37.8 1.8 1.8e-06 28.4 0.1 3.1 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEG48915.1 - 5e-07 29.6 0.3 0.00038 20.3 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEG48915.1 - 1.2e-06 28.6 0.2 0.00069 19.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CEG48915.1 - 2.2e-06 27.2 0.1 3.9e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CEG48915.1 - 1.2e-05 25.6 0.1 0.036 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG48915.1 - 7.9e-05 23.1 0.3 0.00049 20.5 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CEG48915.1 - 0.0001 21.7 0.8 0.0039 16.6 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CEG48915.1 - 0.00023 21.5 0.9 0.0018 18.6 0.9 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CEG48915.1 - 0.00043 20.2 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.26 CEG48915.1 - 0.0007 19.3 0.1 0.46 10.2 0.1 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 CEG48915.1 - 0.0011 18.6 0.5 0.0031 17.1 0.2 1.9 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 CEG48915.1 - 0.0027 17.1 0.2 0.0057 16.0 0.2 1.7 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 CEG48915.1 - 0.0088 16.0 1.2 0.018 15.1 0.2 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CEG48915.1 - 0.016 14.9 1.4 0.32 10.7 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEG48915.1 - 0.017 14.7 0.1 0.075 12.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CEG48915.1 - 0.019 14.3 0.3 0.04 13.2 0.3 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 CEG48915.1 - 0.045 14.2 0.1 0.086 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CEG48915.1 - 0.045 13.8 0.0 0.73 9.9 0.2 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 CEG48915.1 - 0.047 14.2 0.4 0.23 12.0 0.1 2.4 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 CEG48915.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 CEG48915.1 - 0.084 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEG48915.1 - 0.095 11.8 0.2 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 CEG48915.1 - 0.11 12.4 0.3 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CEG48915.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol3_delta2 PF13177.6 CEG48915.1 - 0.21 11.4 0.7 2.3 8.0 0.0 2.3 2 1 0 2 2 2 0 DNA polymerase III, delta subunit FYVE_2 PF02318.16 CEG48917.1 - 0.087 13.0 6.4 0.15 12.3 6.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG48917.1 - 3.8 7.7 15.9 7.5 6.8 15.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger Na_Ca_ex PF01699.24 CEG48919.1 - 1.4e-37 129.0 40.5 4.9e-21 75.3 18.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ADH_N PF08240.12 CEG48921.1 - 1.8e-25 89.0 2.8 3.7e-25 87.9 2.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEG48921.1 - 2e-17 63.4 2.0 3.4e-17 62.7 2.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEG48921.1 - 3.1e-06 26.7 0.1 6.5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEG48921.1 - 6.6e-06 25.6 1.4 1.2e-05 24.8 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 CEG48921.1 - 0.0084 14.9 0.1 0.012 14.3 0.1 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_2 PF03446.15 CEG48921.1 - 0.018 15.2 1.9 0.19 11.9 0.4 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 CEG48921.1 - 0.02 15.7 0.2 0.089 13.6 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 CEG48921.1 - 0.024 15.3 2.2 3.7 8.3 0.1 2.5 2 0 0 2 2 2 0 CoA binding domain ELFV_dehydrog PF00208.21 CEG48921.1 - 0.027 14.2 0.2 0.059 13.1 0.2 1.7 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pectinesterase PF01095.19 CEG48923.1 - 3e-33 114.8 3.2 4.7e-33 114.2 3.2 1.3 1 1 0 1 1 1 1 Pectinesterase MFS_1 PF07690.16 CEG48927.1 - 8.7e-35 120.3 19.8 8.7e-35 120.3 19.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CEG48927.1 - 3.1e-27 95.1 18.2 6.5e-20 70.9 1.3 3.2 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CEG48927.1 - 4.9e-21 75.1 14.7 4.9e-21 75.1 14.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter RhodobacterPufX PF11511.8 CEG48927.1 - 4 7.1 7.9 3.1 7.5 0.1 3.5 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Actin PF00022.19 CEG48928.1 - 8.3e-130 433.0 0.0 3.3e-129 431.1 0.0 1.7 1 1 0 1 1 1 1 Actin Symplekin_C PF12295.8 CEG48929.1 - 9.3e-43 146.5 4.8 9.3e-43 146.5 4.8 3.9 4 0 0 4 4 4 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 CEG48929.1 - 2.1e-11 43.9 2.0 6.9e-11 42.2 2.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) SLATT_1 PF18181.1 CEG48929.1 - 1.6 8.7 5.6 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 CDT1_C PF16679.5 CEG48929.1 - 4.3 7.8 9.0 0.3 11.5 0.4 3.6 3 1 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Aminotran_1_2 PF00155.21 CEG48930.1 - 4.8e-50 170.7 0.0 5.6e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEG48930.1 - 1.1e-05 24.9 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEG48930.1 - 0.00018 21.0 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CEG48930.1 - 0.00071 18.2 0.0 0.0011 17.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEG48930.1 - 0.003 16.6 0.1 0.0046 16.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 CEG48930.1 - 0.0047 15.7 0.9 0.0088 14.8 0.3 1.7 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain tRNA_int_endo_N PF02778.14 CEG48931.1 - 0.053 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Myosin_head PF00063.21 CEG48932.1 - 1.3e-220 734.2 8.1 1.3e-220 734.2 8.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CEG48932.1 - 2.5e-07 29.9 24.5 0.04 13.7 0.5 6.0 6 0 0 6 6 6 4 IQ calmodulin-binding motif WW PF00397.26 CEG48932.1 - 2.8e-07 30.5 0.0 5.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 WW domain Rootletin PF15035.6 CEG48932.1 - 0.0064 16.5 13.2 0.015 15.3 13.2 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion AAA_22 PF13401.6 CEG48932.1 - 0.063 13.5 0.0 0.52 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CEG48932.1 - 0.12 12.7 3.4 0.19 12.1 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain FAM76 PF16046.5 CEG48932.1 - 0.13 11.6 13.2 0.29 10.4 13.2 1.5 1 0 0 1 1 1 0 FAM76 protein AAA_18 PF13238.6 CEG48932.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 CEG48932.1 - 0.65 9.9 6.6 1.4 8.8 0.1 3.4 3 0 0 3 3 3 0 Microtubule binding Fib_alpha PF08702.10 CEG48932.1 - 5.8 7.1 12.1 2.8e+03 -1.6 12.1 2.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG5 PF10392.9 CEG48933.1 - 5.6e-11 42.7 5.4 5.6e-11 42.7 5.4 3.1 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Zw10 PF06248.13 CEG48933.1 - 0.0022 16.7 11.1 0.0022 16.7 11.1 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Sigma70_ner PF04546.13 CEG48933.1 - 0.011 15.6 0.9 0.011 15.6 0.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region COG2 PF06148.11 CEG48933.1 - 0.012 15.7 4.9 0.012 15.7 4.9 3.3 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2570 PF10828.8 CEG48933.1 - 0.016 15.0 6.1 0.56 10.0 0.9 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2570) H-kinase_dim PF02895.14 CEG48933.1 - 0.071 13.5 1.3 2.9 8.3 0.2 3.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Sec8_exocyst PF04048.14 CEG48933.1 - 0.1 12.5 8.1 0.063 13.2 4.5 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TACC_C PF05010.14 CEG48933.1 - 0.11 12.3 5.6 0.52 10.1 5.4 2.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Hrs_helical PF12210.8 CEG48933.1 - 0.16 12.5 3.4 2.2 8.9 1.9 3.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Prominin PF05478.11 CEG48933.1 - 1.2 7.0 6.5 2.7 5.8 6.5 1.6 1 0 0 1 1 1 0 Prominin Peptidase_M1 PF01433.20 CEG48934.1 - 9e-29 100.6 0.5 1.6e-28 99.8 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458_C PF17432.2 CEG48934.1 - 1.9e-21 76.8 0.0 1e-20 74.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1_N PF17900.1 CEG48934.1 - 3.2e-12 47.0 0.1 6.9e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 CEG48934.1 - 5.7e-09 36.3 0.0 1.5e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Rad1 PF02144.16 CEG48935.1 - 2.3e-43 148.3 1.2 3.4e-43 147.7 1.2 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 MCM PF00493.23 CEG48936.1 - 5.7e-73 244.7 0.0 9.8e-73 243.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEG48936.1 - 7e-24 84.1 1.8 1.4e-23 83.1 1.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEG48936.1 - 1.4e-15 57.5 3.4 4e-15 56.0 3.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CEG48936.1 - 6.4e-08 32.2 0.1 0.00022 20.6 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEG48936.1 - 2.7e-07 30.7 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG48936.1 - 0.031 14.7 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEG48936.1 - 0.054 12.8 0.7 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 CEG48936.1 - 0.12 12.8 0.0 0.39 11.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ssu72 PF04722.13 CEG48937.1 - 5.2e-61 205.5 0.0 6.7e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein A_thal_3526 PF09713.10 CEG48937.1 - 0.16 12.2 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) FHA PF00498.26 CEG48939.1 - 1.9e-27 95.4 2.7 3.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 CEG48939.1 - 2.6e-15 56.5 0.0 2.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Defensin_beta PF00711.19 CEG48939.1 - 0.016 15.2 0.7 0.039 14.0 0.7 1.7 1 0 0 1 1 1 0 Beta defensin ALG11_N PF15924.5 CEG48940.1 - 1.3e-76 257.3 0.2 2.1e-76 256.6 0.2 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CEG48940.1 - 2.3e-25 89.1 0.1 4e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG48940.1 - 2.3e-14 53.9 0.1 4.4e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEG48940.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HOCHOB PF17943.1 CEG48940.1 - 0.098 13.4 0.1 0.21 12.3 0.1 1.5 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox E1-E2_ATPase PF00122.20 CEG48941.1 - 8.5e-48 162.3 3.5 3.7e-47 160.2 1.8 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEG48941.1 - 6.1e-25 87.1 0.0 1.4e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEG48941.1 - 1.9e-19 70.8 0.1 6.8e-09 36.3 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 CEG48941.1 - 4.3e-17 62.4 0.0 4.3e-17 62.4 0.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CEG48941.1 - 1.1e-13 50.7 0.0 3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEG48941.1 - 8.8e-05 22.4 3.0 0.0037 17.0 0.5 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 CEG48941.1 - 0.12 12.7 5.9 3.7 7.9 3.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4282 PF14110.6 CEG48941.1 - 0.8 10.5 14.6 16 6.3 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF3040 PF11239.8 CEG48941.1 - 4 7.8 6.1 1.9 8.8 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) HTH_Tnp_Tc5 PF03221.16 CEG48943.1 - 3.3e-16 59.0 0.3 3.9e-14 52.4 0.1 2.6 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain HTH_33 PF13592.6 CEG48943.1 - 0.13 11.9 0.9 0.9 9.2 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn helix ATG16 PF08614.11 CEG48944.1 - 0.00016 21.9 57.0 0.0012 19.1 25.4 11.8 1 1 9 12 12 12 3 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 CEG48944.1 - 0.00025 21.3 5.5 0.00025 21.3 5.5 11.9 4 2 8 13 13 13 3 Domain of unknown function (DUF5082) Intein_splicing PF14890.6 CEG48944.1 - 0.0047 16.9 0.3 0.062 13.3 0.0 3.2 3 1 0 3 3 3 1 Intein splicing domain YjfB_motility PF14070.6 CEG48944.1 - 5.6 7.2 7.4 13 6.0 0.9 4.1 3 0 0 3 3 3 0 Putative motility protein Enolase_N PF03952.16 CEG48946.1 - 2e-22 79.7 0.2 7.9e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 Enolase, N-terminal domain Enolase_C PF00113.22 CEG48946.1 - 5e-13 49.0 0.4 4.9e-06 26.0 0.0 3.5 2 1 1 3 3 3 2 Enolase, C-terminal TIM barrel domain Pkinase PF00069.25 CEG48947.1 - 2.3e-74 250.1 0.0 3.3e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48947.1 - 1.1e-34 119.9 0.0 2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PRCC PF10253.9 CEG48947.1 - 1.2e-07 32.8 15.0 6.8e-07 30.3 15.0 2.3 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Kinase-like PF14531.6 CEG48947.1 - 3.4e-05 23.3 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CEG48947.1 - 0.0032 17.1 0.1 0.0068 16.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEG48947.1 - 0.015 14.2 0.1 0.047 12.6 0.1 1.8 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEG48947.1 - 0.027 14.1 0.1 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEG48947.1 - 0.053 13.4 0.1 0.4 10.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEG48947.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Band_3_cyto PF07565.13 CEG48947.1 - 0.59 9.9 3.0 1.2 8.9 3.0 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NMD3 PF04981.13 CEG48948.1 - 4.4e-70 235.9 13.7 8.6e-70 235.0 13.7 1.5 1 0 0 1 1 1 1 NMD3 family CxC5 PF18718.1 CEG48948.1 - 0.021 14.9 0.9 0.056 13.5 0.9 1.7 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases IRK_C PF17655.1 CEG48949.1 - 1.7e-24 86.4 0.1 1.4e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CEG48949.1 - 5e-13 49.1 4.5 8e-11 41.9 4.5 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CEG48949.1 - 0.002 18.0 8.3 0.0041 17.0 8.3 1.5 1 0 0 1 1 1 1 Ion channel CENP-B_N PF04218.13 CEG48949.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TIM PF00121.18 CEG48950.1 - 5.3e-83 278.1 0.3 6.6e-83 277.8 0.3 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_N PF00044.24 CEG48950.1 - 5e-15 55.7 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CEG48950.1 - 0.057 13.5 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PhoLip_ATPase_C PF16212.5 CEG48951.1 - 1.1e-69 235.0 23.1 1.1e-69 235.0 23.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG48951.1 - 1.6e-26 91.8 0.9 6.5e-26 89.8 0.9 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG48951.1 - 8.5e-11 42.5 1.2 5.9e-05 23.4 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG48951.1 - 1.2e-10 41.4 0.0 6.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG48951.1 - 3.5e-06 26.7 0.0 1.3e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG48951.1 - 0.0026 17.5 0.1 0.0055 16.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 CEG48951.1 - 0.015 15.6 0.3 0.015 15.6 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DnaJ PF00226.31 CEG48952.1 - 0.016 15.3 0.4 0.028 14.6 0.4 1.4 1 0 0 1 1 1 0 DnaJ domain DUF2868 PF11067.8 CEG48952.1 - 0.09 12.3 1.9 0.11 12.0 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) GTP1_OBG PF01018.22 CEG48953.1 - 7.8e-40 136.0 6.3 1.1e-39 135.5 6.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CEG48953.1 - 2.8e-21 75.7 0.0 6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG48953.1 - 1.4e-08 34.4 0.0 1.3e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 CEG48953.1 - 0.0055 17.2 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Arf PF00025.21 CEG48953.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 CEG48953.1 - 0.06 13.9 0.8 0.61 10.6 0.0 2.8 4 0 0 4 4 4 0 AAA domain Gtr1_RagA PF04670.12 CEG48953.1 - 0.22 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_L6e PF01159.19 CEG48954.1 - 7.9e-37 126.2 1.1 7.9e-37 126.2 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L6e E1-E2_ATPase PF00122.20 CEG48955.1 - 1.7e-39 135.2 1.3 1.7e-39 135.2 1.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEG48955.1 - 2e-37 129.5 0.1 4.7e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CEG48955.1 - 4.3e-08 33.5 0.1 1.7e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CEG48955.1 - 0.00022 21.0 0.1 0.0042 16.9 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEG48955.1 - 0.00031 21.2 0.0 0.00087 19.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAP206 PF12018.8 CEG48956.1 - 9.5e-11 41.7 5.1 0.0022 17.6 0.0 5.1 4 1 1 5 5 5 3 Domain of unknown function AAA_18 PF13238.6 CEG48956.1 - 5.7e-07 30.1 0.0 0.00015 22.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CEG48956.1 - 3.2e-06 27.6 0.0 0.00051 20.5 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG48956.1 - 4.7e-06 27.1 0.0 0.013 15.9 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CEG48956.1 - 1.3e-05 25.4 0.0 1.3e-05 25.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain SKI PF01202.22 CEG48956.1 - 1.4e-05 25.3 0.2 0.00025 21.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_5 PF07728.14 CEG48956.1 - 0.00016 21.7 0.0 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CEG48956.1 - 0.00027 21.2 0.0 0.00027 21.2 0.0 2.9 4 0 0 4 4 2 1 AAA domain IstB_IS21 PF01695.17 CEG48956.1 - 0.00059 19.6 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 CEG48956.1 - 0.0007 19.5 0.0 0.0022 17.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Cytidylate_kin2 PF13189.6 CEG48956.1 - 0.0034 17.5 0.0 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.6 CEG48956.1 - 0.0039 17.5 0.0 0.048 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 CEG48956.1 - 0.0052 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Cytidylate kinase ABC_tran PF00005.27 CEG48956.1 - 0.0074 16.8 0.0 0.048 14.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Hydin_ADK PF17213.3 CEG48956.1 - 0.016 15.5 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ADK PF00406.22 CEG48956.1 - 0.02 15.0 0.0 3.3 7.8 0.0 3.2 4 0 0 4 4 2 0 Adenylate kinase AAA_17 PF13207.6 CEG48956.1 - 0.022 15.2 0.0 0.084 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEG48956.1 - 0.024 15.0 0.1 0.19 12.1 0.0 2.6 3 0 0 3 3 2 0 RNA helicase RuvB_N PF05496.12 CEG48956.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CEG48956.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEG48956.1 - 0.066 12.3 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KTI12 PF08433.10 CEG48956.1 - 0.096 12.1 0.0 31 3.9 0.0 3.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 YHS PF04945.13 CEG48956.1 - 0.5 10.5 10.8 4.4 7.5 0.4 5.0 5 0 0 5 5 5 0 YHS domain Pkinase PF00069.25 CEG48958.1 - 1.2e-36 126.4 0.0 1.8e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG48958.1 - 8.4e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG48958.1 - 3e-07 30.1 0.0 4.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Fer2_2 PF01799.20 CEG48968.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 [2Fe-2S] binding domain Retrotrans_gag PF03732.17 CEG48969.1 - 3.2e-09 36.9 0.0 6.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 CEG48969.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP1_TIP1 PF00660.17 CEG48972.1 - 0.067 13.3 0.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 Seripauperin and TIP1 family SIX1_SD PF16878.5 CEG48972.1 - 0.1 13.1 2.8 0.5 10.9 0.0 3.1 4 0 0 4 4 4 0 Transcriptional regulator, SIX1, N-terminal SD domain Cdc13_OB4_dimer PF18233.1 CEG48972.1 - 0.11 12.6 2.2 0.61 10.2 0.7 2.7 2 1 1 3 3 3 0 Cdc13 OB4 dimerization domain DUF3107 PF11305.8 CEG48972.1 - 0.34 11.2 2.0 1.9 8.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) DUF2789 PF10982.8 CEG48972.1 - 4.8 7.4 6.3 45 4.3 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2789) RNase_E_G PF10150.9 CEG48975.1 - 0.005 16.3 0.6 0.87 8.9 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease E/G family APAF1_C PF17908.1 CEG48975.1 - 0.047 13.7 0.6 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 APAF-1 helical domain HisK_N PF09385.10 CEG48975.1 - 0.09 12.7 1.2 0.23 11.4 0.1 2.2 2 2 1 3 3 3 0 Histidine kinase N terminal Acetyltransf_1 PF00583.25 CEG48976.1 - 3.3e-14 53.1 0.0 6.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG48976.1 - 3.6e-10 39.9 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG48976.1 - 1.6e-09 38.0 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG48976.1 - 1.5e-07 31.3 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEG48976.1 - 0.0036 17.4 0.1 0.011 15.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEG48976.1 - 0.0048 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_ABP1_N PF18107.1 CEG48978.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CEG48978.1 - 0.0039 17.8 0.0 0.0073 16.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc5 PF03221.16 CEG48978.1 - 0.0075 16.3 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 CEG48978.1 - 0.013 15.8 0.2 0.021 15.0 0.2 1.4 1 0 0 1 1 1 0 Transposase PGP_phosphatase PF09419.10 CEG48978.1 - 0.017 14.8 0.1 0.032 13.9 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DUF5395 PF17373.2 CEG48978.1 - 0.074 13.7 0.1 0.13 13.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5395) RPM2 PF08579.11 CEG48978.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) HTH_33 PF13592.6 CEG48978.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix AnmK PF03702.14 CEG48978.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase MtN3_slv PF03083.16 CEG48981.1 - 9.3e-09 35.2 11.9 2.7e-06 27.3 3.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Lung_7-TM_R PF06814.13 CEG48982.1 - 3.3e-41 141.5 15.8 4.9e-41 140.9 15.8 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor U-box PF04564.15 CEG48983.1 - 7.5e-26 90.1 0.0 7.5e-26 90.1 0.0 1.9 3 0 0 3 3 2 1 U-box domain TPR_1 PF00515.28 CEG48983.1 - 3e-13 48.9 5.7 0.0001 22.0 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG48983.1 - 1.5e-10 40.3 5.2 0.0068 16.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEG48983.1 - 1.3e-06 28.0 1.0 0.00019 21.1 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 CEG48983.1 - 4.5e-06 27.2 0.2 0.0051 17.4 0.0 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG48983.1 - 4.6e-05 23.3 4.6 0.096 13.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG48983.1 - 0.00018 21.7 5.0 1.8 8.9 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 CEG48983.1 - 0.00068 19.7 0.2 0.0031 17.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 CEG48983.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TPR_9 PF13371.6 CEG48983.1 - 0.002 18.2 0.8 2.9 8.1 0.1 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG48983.1 - 0.0057 17.4 0.3 1.1 10.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG48983.1 - 0.0084 16.4 2.0 3.4 8.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-Nse PF11789.8 CEG48983.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_7 PF13176.6 CEG48983.1 - 0.059 13.4 0.0 1.1 9.5 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG48983.1 - 0.07 13.4 6.3 1.9 8.8 3.5 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEG48983.1 - 0.15 12.7 3.2 8.6 7.2 0.3 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1856 PF08983.10 CEG48984.1 - 0.037 14.3 0.8 1.2 9.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) RCC1 PF00415.18 CEG48985.1 - 5e-73 241.6 13.5 8.1e-15 55.2 0.2 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 CEG48985.1 - 5.8e-41 140.5 0.4 9.5e-41 139.8 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RCC1_2 PF13540.6 CEG48985.1 - 9.3e-37 124.1 36.0 3.1e-09 36.4 0.2 7.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PX PF00787.24 CEG48985.1 - 6.2e-06 26.2 0.2 6.2e-06 26.2 0.2 2.3 2 0 0 2 2 2 1 PX domain Hira PF07569.11 CEG48985.1 - 0.043 13.5 0.7 66 3.1 0.0 4.0 4 0 0 4 4 4 0 TUP1-like enhancer of split Peroxidase_2 PF01328.17 CEG48987.1 - 6.2 7.3 8.8 0.59 10.6 0.7 2.8 1 1 1 2 2 2 0 Peroxidase, family 2 Cnd3 PF12719.7 CEG48988.1 - 1.3e-38 132.9 6.0 1.3e-38 132.9 6.0 3.3 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CEG48988.1 - 9.2e-07 29.2 1.8 0.003 17.9 0.0 4.3 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 CEG48988.1 - 2.4e-05 24.2 3.8 7 7.2 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat EDR1 PF14381.6 CEG48988.1 - 0.0055 16.4 2.1 0.2 11.3 0.2 2.9 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 RVT_2 PF07727.14 CEG48989.1 - 8.1e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ADAM_spacer1 PF05986.14 CEG48989.1 - 0.064 13.3 1.5 4.4 7.4 0.1 2.1 1 1 1 2 2 2 0 ADAM-TS Spacer 1 MMPL PF03176.15 CEG48989.1 - 0.31 9.9 1.0 0.36 9.7 1.0 1.1 1 0 0 1 1 1 0 MMPL family Membralin PF09746.9 CEG48989.1 - 3.8 6.5 5.3 4.3 6.3 5.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein Pectate_lyase PF03211.13 CEG48991.1 - 4.4e-80 268.0 8.6 5.1e-80 267.8 8.6 1.0 1 0 0 1 1 1 1 Pectate lyase Pectate_lyase PF03211.13 CEG48992.1 - 4.9e-06 26.2 0.1 8.2e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Pectate lyase Kazal_2 PF07648.15 CEG48992.1 - 0.0078 16.3 1.1 0.018 15.1 1.1 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG48992.1 - 0.039 14.0 0.4 0.095 12.7 0.4 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Retrotran_gag_2 PF14223.6 CEG48993.1 - 2.9e-23 82.0 0.3 4.1e-23 81.6 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 CEG48993.1 - 0.0067 16.7 0.9 0.0093 16.2 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3307 PF11750.8 CEG48994.1 - 0.11 12.5 0.8 0.12 12.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) Herpes_IE2_3 PF03361.14 CEG48995.1 - 0.016 15.1 0.2 0.035 14.0 0.1 1.6 1 1 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 RXLR_WY PF18634.1 CEG48995.1 - 0.64 10.0 0.1 0.64 10.0 0.1 3.2 3 1 1 4 4 4 0 RXLR phytopathogen effector protein WY-domain DDOST_48kD PF03345.14 CEG48996.1 - 0.015 14.1 0.8 0.018 13.9 0.8 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF4482 PF14818.6 CEG48996.1 - 3.8 8.4 11.1 0.19 12.6 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) AAA_33 PF13671.6 CEG48997.1 - 5.7e-10 39.5 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG48997.1 - 2.5e-06 26.9 0.0 7.1e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 CEG48997.1 - 0.00043 19.8 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CEG48997.1 - 0.0023 18.5 0.0 0.007 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain tRNA_lig_CPD PF08302.11 CEG48997.1 - 0.0064 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_22 PF13401.6 CEG48997.1 - 0.033 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CEG48997.1 - 0.17 11.2 3.0 0.24 10.7 0.2 2.4 2 1 0 2 2 2 0 6-phosphofructo-2-kinase Peptidase_S15 PF02129.18 CEG48998.1 - 1.1e-32 113.7 0.1 2.2e-32 112.7 0.1 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 CEG48998.1 - 5.3e-13 49.4 0.1 1.1e-12 48.4 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 CEG48998.1 - 0.00012 21.4 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cytochrom_B561 PF03188.16 CEG48999.1 - 1.9e-16 60.5 8.5 3.2e-16 59.7 8.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Frag1 PF10277.9 CEG48999.1 - 0.38 10.2 7.3 0.47 10.0 7.3 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Cytochrom_B561 PF03188.16 CEG49000.1 - 8.4e-09 35.7 11.1 1.5e-07 31.6 1.8 2.5 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 Mannosyl_trans3 PF11051.8 CEG49002.1 - 1.3e-32 113.3 0.0 1.3e-31 110.0 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative E1-E2_ATPase PF00122.20 CEG49002.1 - 0.36 10.3 0.9 0.71 9.4 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase Bot1p PF12298.8 CEG49003.1 - 0.0035 17.5 4.3 0.011 16.0 4.3 1.8 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 CEG49003.1 - 0.064 13.4 11.6 2.5 8.2 8.2 3.2 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Mannosyl_trans3 PF11051.8 CEG49003.1 - 0.087 12.2 0.2 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Retrotrans_gag PF03732.17 CEG49005.1 - 2.1e-09 37.5 0.0 6.3e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEG49005.1 - 0.058 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RabGAP-TBC PF00566.18 CEG49008.1 - 7.7e-63 212.0 20.1 1.6e-32 112.9 0.1 2.9 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Glyco_hydro_47 PF01532.20 CEG49010.1 - 5.8e-107 358.4 0.0 1.2e-105 354.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 PA PF02225.22 CEG49010.1 - 8.2e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 PA domain WD40 PF00400.32 CEG49011.1 - 4.7e-06 27.2 1.5 0.78 10.7 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PP2C PF00481.21 CEG49012.1 - 4.7e-37 128.0 0.0 9.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 CEG49012.1 - 1.8e-32 111.3 0.0 1.6e-15 57.0 0.0 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 CEG49012.1 - 2.3e-31 109.1 0.0 4.5e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49012.1 - 2.3e-10 40.2 0.0 4.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG49012.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PP2C_2 PF13672.6 CEG49012.1 - 0.00031 20.4 0.1 0.00093 18.9 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C PhyH PF05721.13 CEG49013.1 - 6.5e-13 49.4 0.0 9.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhoLip_ATPase_C PF16212.5 CEG49014.1 - 3.5e-70 236.6 17.2 3.5e-70 236.6 17.2 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEG49014.1 - 1.3e-19 69.6 4.6 1.3e-19 69.6 4.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEG49014.1 - 1.5e-10 41.7 1.1 2.9e-05 24.5 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEG49014.1 - 2.8e-10 40.1 0.1 4.3e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEG49014.1 - 2.1e-07 30.6 0.0 8.4e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEG49014.1 - 0.00028 20.7 0.1 0.00082 19.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Got1 PF04178.12 CEG49015.1 - 1.5e-22 80.1 15.8 2.5e-22 79.4 15.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Pex14_N PF04695.13 CEG49015.1 - 0.048 14.3 0.1 0.075 13.7 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.29 CEG49018.1 - 9e-19 67.9 0.3 3.2e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG49018.1 - 2.2e-17 63.4 0.0 1.7e-15 57.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CEG49018.1 - 0.00016 22.3 2.9 0.00068 20.3 2.9 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CEG49018.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CEG49018.1 - 0.0015 18.4 2.5 0.0018 18.2 0.1 2.2 2 0 0 2 2 2 1 HRDC domain SNF2_N PF00176.23 CEG49018.1 - 0.0033 16.2 0.0 0.0049 15.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_2 PF07724.14 CEG49019.1 - 5.5e-50 169.8 0.3 6.6e-46 156.5 0.0 3.6 3 1 1 4 4 4 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CEG49019.1 - 6.8e-33 112.7 2.9 6.8e-33 112.7 2.9 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CEG49019.1 - 1e-24 86.4 0.1 3.6e-24 84.6 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CEG49019.1 - 9e-21 74.7 0.7 1.4e-12 48.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG49019.1 - 1.8e-17 63.6 2.2 4.8e-12 46.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG49019.1 - 4.6e-08 33.4 0.3 0.0032 17.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CEG49019.1 - 3.9e-07 29.9 0.1 0.004 16.9 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 CEG49019.1 - 1.2e-06 29.1 11.8 0.00043 20.7 0.1 5.0 4 2 1 6 6 6 2 AAA ATPase domain AAA_18 PF13238.6 CEG49019.1 - 1e-05 26.1 3.5 0.27 11.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 CEG49019.1 - 1.4e-05 24.9 0.0 0.071 12.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 CEG49019.1 - 6.6e-05 22.6 4.4 0.00086 18.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 CEG49019.1 - 6.6e-05 22.7 0.2 0.39 10.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 CEG49019.1 - 8e-05 22.1 0.2 0.45 9.9 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CEG49019.1 - 0.00017 21.1 0.0 0.15 11.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CEG49019.1 - 0.00024 21.5 0.0 1.6 9.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 CEG49019.1 - 0.00085 19.3 0.0 1.5 8.7 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CEG49019.1 - 0.00085 19.3 0.0 0.055 13.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 CEG49019.1 - 0.0013 18.7 4.8 3.8 7.4 0.1 4.7 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CEG49019.1 - 0.0014 18.8 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CEG49019.1 - 0.002 18.1 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CEG49019.1 - 0.0031 17.3 5.0 3.5 7.3 1.4 3.6 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 CEG49019.1 - 0.0044 17.2 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CEG49019.1 - 0.0084 16.4 1.1 9.1 6.5 0.0 3.7 3 1 1 4 4 3 0 AAA domain DNA_pol3_delta2 PF13177.6 CEG49019.1 - 0.0094 15.7 0.0 0.67 9.7 0.0 3.5 3 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 CEG49019.1 - 0.013 15.4 0.1 6.9 6.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CEG49019.1 - 0.023 13.9 0.1 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_23 PF13476.6 CEG49019.1 - 0.024 15.1 12.5 3.8 8.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEG49019.1 - 0.032 14.6 3.3 1.2 9.4 0.6 3.5 2 2 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CEG49019.1 - 0.035 13.9 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CEG49019.1 - 0.055 14.0 1.0 7 7.2 0.0 3.4 3 1 0 3 3 3 0 ABC transporter ATP_bind_1 PF03029.17 CEG49019.1 - 0.18 11.6 0.7 2.7 7.7 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein TPR_MLP1_2 PF07926.12 CEG49019.1 - 0.2 11.7 11.6 0.47 10.5 11.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 CEG49019.1 - 0.4 8.5 2.1 0.51 8.2 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CEG49019.1 - 0.59 9.0 1.1 0.79 8.6 0.5 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein SRP54 PF00448.22 CEG49019.1 - 0.61 9.7 3.7 4.5 6.9 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain APG6_N PF17675.1 CEG49019.1 - 1.1 9.8 13.5 3.1 8.3 13.5 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 CEG49019.1 - 3.1 6.8 6.3 5.8 5.9 6.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 CEG49019.1 - 6.4 7.1 10.5 12 6.2 9.7 1.9 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) Ysc84 PF04366.12 CEG49020.1 - 2e-33 114.9 0.2 4.2e-33 113.8 0.2 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 CEG49020.1 - 7.4e-13 48.4 4.4 7.4e-13 48.4 4.4 2.8 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 CEG49020.1 - 0.017 15.3 0.7 0.017 15.3 0.7 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 CEG49020.1 - 0.02 14.9 0.9 0.02 14.9 0.9 3.3 2 1 0 2 2 2 0 Double zinc ribbon Prok-RING_2 PF14445.6 CEG49020.1 - 0.085 13.0 3.8 0.27 11.4 3.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zinc_ribbon_2 PF13240.6 CEG49020.1 - 0.088 12.6 12.4 0.12 12.2 6.7 3.6 2 1 1 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEG49020.1 - 0.69 9.9 7.5 6.8 6.8 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbons PolyA_pol PF01743.20 CEG49021.1 - 7.2e-11 42.6 0.1 8.1e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Poly A polymerase head domain PDT PF00800.18 CEG49022.1 - 2.7e-13 50.2 0.3 7.9e-12 45.4 0.1 2.3 1 1 1 2 2 2 1 Prephenate dehydratase ACT PF01842.25 CEG49022.1 - 0.014 15.2 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 ACT domain STI1 PF17830.1 CEG49025.1 - 0.0079 16.1 0.2 0.082 12.9 0.0 2.6 2 0 0 2 2 2 1 STI1 domain Alpha_Helical PF18489.1 CEG49025.1 - 0.067 13.4 1.2 0.18 12.0 0.1 2.3 2 0 0 2 2 2 0 Alpha helical domain Nif11 PF07862.11 CEG49025.1 - 0.77 10.1 10.4 8.6 6.8 0.2 4.5 5 0 0 5 5 5 0 Nif11 domain DUF1772 PF08592.11 CEG49026.1 - 2.2e-08 34.5 0.2 2.8e-08 34.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) His_Phos_1 PF00300.22 CEG49027.1 - 0.017 14.8 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Herpes_teg_N PF04843.12 CEG49028.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region FAM91_N PF14647.6 CEG49029.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 FAM91 N-terminus G2BR PF18442.1 CEG49030.1 - 0.13 11.9 0.8 0.13 11.9 0.8 2.1 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) RVT_2 PF07727.14 CEG49031.1 - 3.6e-30 105.4 0.7 4.2e-30 105.2 0.7 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG49031.1 - 0.0041 16.6 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 CEG49035.1 - 3.1e-13 49.7 0.1 1.7e-06 27.6 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 CEG49035.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 CEG49036.1 - 8.3e-44 149.2 0.0 1.8e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEG49036.1 - 1.5e-10 40.8 0.1 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CEG49036.1 - 2.7e-08 33.9 0.1 9.5e-08 32.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEG49036.1 - 9.9e-08 32.3 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CEG49036.1 - 3.5e-06 26.7 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CEG49036.1 - 1.5e-05 25.4 0.2 0.0022 18.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CEG49036.1 - 0.00022 20.5 0.0 0.00065 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEG49036.1 - 0.00025 21.3 0.5 0.019 15.3 0.5 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEG49036.1 - 0.00026 20.8 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CEG49036.1 - 0.00028 20.9 0.1 0.025 14.5 0.0 2.9 3 0 0 3 3 3 1 NTPase Mg_chelatase PF01078.21 CEG49036.1 - 0.00057 19.3 0.1 0.0014 18.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CEG49036.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CEG49036.1 - 0.0014 19.2 0.0 0.0037 17.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CEG49036.1 - 0.0016 18.7 0.1 0.0049 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEG49036.1 - 0.0023 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEG49036.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 CEG49036.1 - 0.0027 17.7 0.0 0.037 14.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEG49036.1 - 0.0054 16.3 0.1 0.026 14.0 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CEG49036.1 - 0.0063 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 CEG49036.1 - 0.009 15.8 0.4 0.02 14.6 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEG49036.1 - 0.012 15.4 0.2 0.027 14.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEG49036.1 - 0.013 14.6 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CEG49036.1 - 0.016 14.9 0.2 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 CEG49036.1 - 0.024 14.7 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEG49036.1 - 0.034 14.1 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 CEG49036.1 - 0.06 13.2 0.1 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CEG49036.1 - 0.065 13.1 0.1 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 CEG49036.1 - 0.068 12.6 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 CEG49036.1 - 0.11 11.9 0.2 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 CEG49036.1 - 0.16 11.3 0.8 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 CEG49036.1 - 0.18 11.3 3.1 0.55 9.8 0.3 2.3 1 1 1 2 2 2 0 AAA domain BAF1_ABF1 PF04684.13 CEG49036.1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TB2_DP1_HVA22 PF03134.19 CEG49037.1 - 1.4e-12 47.3 0.6 2.1e-12 46.8 0.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Myb_DNA-binding PF00249.31 CEG49038.1 - 3e-10 40.1 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ifi-6-16 PF06140.13 CEG49039.1 - 6.8e-19 67.6 30.3 1.8e-18 66.2 30.3 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family RRM_1 PF00076.22 CEG49040.1 - 4.8e-07 29.5 0.0 5.7e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG49040.1 - 0.13 12.1 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif RabGAP-TBC PF00566.18 CEG49040.1 - 0.52 9.9 4.2 0.74 9.4 4.2 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Membralin PF09746.9 CEG49040.1 - 4.1 6.3 6.2 6 5.8 6.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein 2OG-FeII_Oxy_3 PF13640.6 CEG49041.1 - 2.3e-11 44.4 0.0 5.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5643 PF18705.1 CEG49041.1 - 0.66 10.0 3.4 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Lectin_leg-like PF03388.13 CEG49042.1 - 1.8e-37 128.9 1.6 3.3e-37 128.0 1.6 1.4 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CEG49042.1 - 2.5e-12 47.2 4.6 4.3e-12 46.5 4.6 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEG49042.1 - 0.00012 21.7 0.7 0.00029 20.4 0.7 1.5 1 1 0 1 1 1 1 Legume lectin domain Nbl1_Borealin_N PF10444.9 CEG49042.1 - 0.034 13.8 1.2 0.081 12.6 1.0 1.7 1 1 0 1 1 1 0 Nbl1 / Borealin N terminal MIS13 PF08202.11 CEG49042.1 - 0.035 13.4 4.2 0.053 12.8 4.2 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Lectin_leg-like PF03388.13 CEG49043.1 - 1.3e-38 132.6 0.4 2e-38 132.0 0.4 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CEG49043.1 - 9.4e-07 29.0 2.5 1.6e-06 28.3 2.5 1.4 1 0 0 1 1 1 1 Bacterial lectin ApoLp-III PF07464.11 CEG49043.1 - 0.00013 22.1 2.7 0.00023 21.3 2.7 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DCB PF16213.5 CEG49043.1 - 0.012 15.2 0.9 0.02 14.5 0.9 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Cortex-I_coil PF09304.10 CEG49043.1 - 0.032 14.4 2.3 0.058 13.6 2.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil TryThrA_C PF12319.8 CEG49043.1 - 0.16 11.4 2.2 0.29 10.6 2.2 1.3 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Nbl1_Borealin_N PF10444.9 CEG49043.1 - 0.22 11.2 1.9 0.32 10.7 0.4 2.0 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal tRNA-synt_1 PF00133.22 CEG49049.1 - 4.4e-202 672.6 0.0 5.2e-201 669.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEG49049.1 - 1.8e-39 135.2 0.0 3.4e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEG49049.1 - 7.3e-16 57.9 1.0 2.3e-07 29.9 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEG49049.1 - 1.2e-10 41.2 0.1 1.7e-07 30.9 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CEG49049.1 - 1.6e-06 28.3 0.6 6.5e-06 26.3 0.6 2.2 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CEG49049.1 - 0.018 14.4 0.0 3.1 7.1 0.0 3.2 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain UPF0231 PF06062.11 CEG49049.1 - 0.059 13.6 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Polysacc_deac_1 PF01522.21 CEG49054.1 - 0.057 13.3 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide deacetylase EF-hand_8 PF13833.6 CEG49055.1 - 0.0021 17.8 0.3 0.0031 17.3 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG49055.1 - 0.0063 16.0 0.3 0.015 14.8 0.3 1.7 1 0 0 1 1 1 1 EF hand RTBV_P46 PF06216.11 CEG49056.1 - 0.053 12.4 0.1 0.058 12.3 0.1 1.0 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein EF-hand_1 PF00036.32 CEG49057.1 - 4.5e-26 88.4 14.5 1.2e-07 30.8 1.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEG49057.1 - 1.5e-22 79.8 8.6 3e-12 46.8 3.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG49057.1 - 6.7e-21 72.4 7.1 1.4e-07 30.9 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CEG49057.1 - 6.9e-18 64.2 14.1 6.3e-12 45.2 1.2 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CEG49057.1 - 1.8e-10 41.0 0.3 4.3e-05 23.7 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG49057.1 - 2.2e-10 39.5 9.1 0.00094 18.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 CEG49057.1 - 0.00044 20.6 1.5 0.39 11.1 0.1 2.8 1 1 2 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CEG49057.1 - 0.00077 19.4 4.2 1.2 9.1 1.4 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 CEG49057.1 - 0.0056 16.6 0.6 0.4 10.5 0.1 2.3 1 1 0 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 CEG49057.1 - 0.0061 16.5 0.9 1.3 8.9 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein SUB1_ProdP9 PF18213.1 CEG49057.1 - 0.011 15.6 1.6 0.19 11.6 0.2 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 CEG49057.1 - 0.022 15.6 0.6 0.42 11.5 0.1 2.3 1 1 0 2 2 2 0 EF-hand domain DUF3892 PF13031.6 CEG49057.1 - 0.043 14.4 0.2 1.4 9.6 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3892) DUF3911 PF13050.6 CEG49057.1 - 0.081 13.0 0.5 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) PEARLI-4 PF05278.12 CEG49057.1 - 0.11 12.0 1.4 0.29 10.7 0.5 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF1100 PF06500.11 CEG49058.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) TMEM18 PF14770.6 CEG49060.1 - 0.067 13.2 0.1 0.075 13.0 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 18 EF-hand_8 PF13833.6 CEG49062.1 - 0.0087 15.9 0.3 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair FadA PF09403.10 CEG49062.1 - 0.088 13.3 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Kazal_2 PF07648.15 CEG49063.1 - 2.5e-09 37.1 4.8 4.7e-09 36.2 4.8 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CEG49063.1 - 4e-07 29.9 3.6 7.4e-07 29.1 3.6 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain IL31 PF15209.6 CEG49063.1 - 0.053 13.3 3.4 12 5.6 0.1 3.7 1 1 3 4 4 4 0 Interleukin 31 eIF-3c_N PF05470.12 CEG49063.1 - 0.064 11.6 0.1 0.082 11.2 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2274 PF10038.9 CEG49063.1 - 0.069 13.6 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) Ag332 PF04671.12 CEG49064.1 - 0.024 14.6 0.4 0.052 13.5 0.4 1.5 1 0 0 1 1 1 0 Erythrocyte membrane-associated giant protein antigen 332 AMPK1_CBM PF16561.5 CEG49064.1 - 0.19 12.0 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase adh_short PF00106.25 CEG49065.1 - 1.1e-48 165.3 4.3 1.4e-48 165.0 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG49065.1 - 5.2e-39 134.2 3.3 1.4e-38 132.7 3.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG49065.1 - 1.4e-13 51.1 1.4 2.3e-13 50.4 1.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEG49065.1 - 0.026 14.4 0.4 0.052 13.4 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VOMI PF03762.17 CEG49065.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) UQ_con PF00179.26 CEG49066.1 - 9e-38 129.1 0.0 1.2e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG49066.1 - 0.15 12.4 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain ANAPC4_WD40 PF12894.7 CEG49067.1 - 8.5e-07 29.2 0.0 0.0057 16.9 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEG49067.1 - 0.00049 20.8 2.8 1.2 10.1 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.6 CEG49067.1 - 0.00063 19.2 0.3 5.3 6.3 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 CEG49067.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A GFO_IDH_MocA PF01408.22 CEG49067.1 - 0.082 13.7 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lactonase PF10282.9 CEG49067.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Gag_spuma PF03276.14 CEG49067.1 - 0.22 9.9 0.9 0.36 9.2 0.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Mucin PF01456.17 CEG49067.1 - 0.78 9.7 4.9 1.3 9.0 4.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Fra10Ac1 PF09725.9 CEG49068.1 - 2.4e-27 95.5 0.1 3.3e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 FHA PF00498.26 CEG49069.1 - 4.1e-17 62.3 0.0 1.1e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG49069.1 - 2.7e-06 27.6 0.0 2.3e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF1192 PF06698.11 CEG49069.1 - 0.0014 18.6 7.1 0.086 12.9 2.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) DUF1179 PF06678.11 CEG49069.1 - 0.01 15.8 0.1 0.038 14.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Cas_GSU0053 PF09617.10 CEG49069.1 - 0.049 13.6 0.2 0.21 11.5 0.1 2.1 3 0 0 3 3 3 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) COG5 PF10392.9 CEG49069.1 - 0.076 13.2 0.6 0.076 13.2 0.6 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 ABC_tran_CTD PF16326.5 CEG49069.1 - 0.083 13.2 19.6 0.25 11.6 2.6 3.9 3 1 1 4 4 4 0 ABC transporter C-terminal domain FlxA PF14282.6 CEG49069.1 - 0.38 10.8 21.7 0.13 12.2 5.3 3.1 3 1 0 3 3 3 0 FlxA-like protein ISG65-75 PF11727.8 CEG49069.1 - 0.55 9.4 12.2 0.091 12.0 4.2 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF4094 PF13334.6 CEG49069.1 - 3.4 8.2 5.8 13 6.2 1.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF724 PF05266.14 CEG49069.1 - 5.9 6.7 14.7 1.1 9.1 6.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 CEG49070.1 - 0.012 13.9 6.7 0.019 13.1 6.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Tup_N PF08581.10 CEG49070.1 - 0.1 12.9 10.7 0.21 11.9 1.4 3.4 3 0 0 3 3 3 0 Tup N-terminal DUF948 PF06103.11 CEG49070.1 - 0.23 11.7 1.4 2.5 8.4 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 CEG49070.1 - 0.6 8.7 3.5 0.49 8.9 1.9 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CEG49070.1 - 7.2 6.8 11.1 1.5 9.0 3.4 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 CEG49073.1 - 1.3e-66 218.9 25.1 1.6e-10 41.4 0.2 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49073.1 - 3.1e-25 88.3 3.9 0.00027 21.2 0.0 6.5 3 2 3 6 6 5 5 Anaphase-promoting complex subunit 4 WD40 domain Dynein_light PF01221.18 CEG49073.1 - 4.2e-20 71.9 0.2 1.1e-19 70.5 0.2 1.7 1 0 0 1 1 1 1 Dynein light chain type 1 eIF2A PF08662.11 CEG49073.1 - 4e-09 36.6 0.3 0.0013 18.6 0.0 4.0 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEG49073.1 - 9.4e-09 34.7 0.4 0.12 11.3 0.1 5.4 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 CEG49073.1 - 9.9e-09 35.6 0.0 2.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CEG49073.1 - 1e-05 24.4 3.5 6.6 5.2 0.0 5.4 3 2 2 6 6 6 3 Nucleoporin Nup120/160 PD40 PF07676.12 CEG49073.1 - 0.00014 21.7 6.8 1.6 8.8 0.0 4.6 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CEG49073.1 - 0.00082 18.8 0.3 1.8 7.8 0.0 4.0 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CEG49073.1 - 0.0023 17.3 0.0 0.15 11.3 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 CEG49073.1 - 0.0058 15.4 0.1 1.9 7.1 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like IKI3 PF04762.12 CEG49073.1 - 0.1 10.6 0.1 0.59 8.0 0.0 2.0 1 1 1 2 2 2 0 IKI3 family HPS3_N PF14761.6 CEG49073.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 CEG49073.1 - 0.18 10.8 0.0 0.58 9.1 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region PALB2_WD40 PF16756.5 CEG49073.1 - 0.2 10.6 4.4 3.6 6.4 0.3 2.9 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 CEG49073.1 - 2.7 7.7 5.7 40 4.0 0.2 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature eRF1_1 PF03463.15 CEG49076.1 - 1.3e-44 151.3 0.4 2.2e-44 150.6 0.4 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CEG49076.1 - 2.9e-29 102.1 0.1 5.6e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEG49076.1 - 6.5e-23 81.4 0.0 1.5e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 Sedlin_N PF04628.13 CEG49077.1 - 3.7e-15 56.2 0.0 4.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RVT_2 PF07727.14 CEG49080.1 - 7.3e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CEG49080.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Ribosomal_L7Ae PF01248.26 CEG49081.1 - 3.2e-25 87.7 0.0 3.7e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PCO_ADO PF07847.12 CEG49082.1 - 9.3e-45 152.5 0.0 1.1e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO ABC_tran PF00005.27 CEG49083.1 - 2e-57 193.6 0.0 6.6e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CEG49083.1 - 5.7e-34 117.7 49.4 4.3e-19 68.8 21.7 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF2401 PF10287.9 CEG49083.1 - 6.2e-33 114.3 1.7 1.2e-32 113.4 1.7 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) AAA_21 PF13304.6 CEG49083.1 - 4.9e-20 72.6 5.7 1.1e-05 25.4 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG49083.1 - 6.1e-11 42.2 0.1 2.1e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG49083.1 - 6.2e-06 25.9 1.4 0.048 13.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG49083.1 - 1.9e-05 25.3 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CEG49083.1 - 0.0047 16.7 0.0 9.8 5.8 0.0 3.5 3 1 0 4 4 4 1 AAA ATPase domain DUF4162 PF13732.6 CEG49083.1 - 0.0067 17.1 0.2 0.82 10.4 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CEG49083.1 - 0.0086 16.0 1.4 2 8.3 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Rad17 PF03215.15 CEG49083.1 - 0.042 13.8 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 CEG49083.1 - 0.062 13.8 0.0 19 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CEG49083.1 - 0.064 12.8 0.2 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEG49083.1 - 0.074 12.8 0.7 7 6.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 CEG49083.1 - 0.11 12.6 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PHD PF00628.29 CEG49084.1 - 1.1e-08 34.8 5.9 2.1e-08 33.9 5.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEG49084.1 - 6.7e-05 23.1 5.5 0.00016 21.9 5.5 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEG49084.1 - 0.011 15.9 1.8 0.025 14.8 1.8 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-PHD-like PF15446.6 CEG49084.1 - 0.011 15.4 2.3 0.024 14.2 2.3 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain tRNA_NucTran2_2 PF13735.6 CEG49084.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Phage-tail_2 PF09096.10 CEG49084.1 - 0.043 13.8 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Baseplate structural protein, domain 2 Prok-RING_1 PF14446.6 CEG49084.1 - 0.51 10.3 6.3 0.27 11.2 3.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CEG49084.1 - 1 9.0 7.5 0.064 12.8 2.1 1.9 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 CEG49084.1 - 6.5 6.7 8.9 17 5.4 3.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) 2OG-FeII_Oxy PF03171.20 CEG49085.1 - 4e-24 85.0 0.1 5.3e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.21 CEG49087.1 - 4.3e-32 111.7 0.0 5.2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEG49087.1 - 3.5e-14 52.4 0.0 4.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Ribosomal_L24e PF01246.20 CEG49088.1 - 8.2e-26 90.0 0.5 8.2e-26 90.0 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Methyltransf_25 PF13649.6 CEG49089.1 - 4.5e-13 49.7 0.0 1.2e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG49089.1 - 1.9e-11 43.9 0.0 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CEG49089.1 - 7.1e-11 42.1 0.1 1.3e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG49089.1 - 6.4e-10 39.5 0.0 1.6e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEG49089.1 - 9.4e-08 31.3 0.1 1.4e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 CEG49089.1 - 2.6e-07 30.6 0.0 1.3e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CEG49089.1 - 2.7e-06 26.9 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CEG49089.1 - 1.4e-05 24.7 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CEG49089.1 - 1.9e-05 24.7 0.1 3.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG49089.1 - 4.6e-05 24.1 0.0 8.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEG49089.1 - 0.00029 20.3 0.2 0.00058 19.3 0.2 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CEG49089.1 - 0.0003 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CEG49089.1 - 0.00064 19.9 0.4 0.002 18.3 0.4 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 CEG49089.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PRMT5 PF05185.16 CEG49089.1 - 0.0031 17.4 0.1 0.0053 16.6 0.1 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 CEG49089.1 - 0.007 16.1 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CEG49089.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 CEG49089.1 - 0.021 14.2 0.8 0.076 12.4 0.8 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 CEG49089.1 - 0.027 13.6 0.0 0.052 12.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Shikimate_DH PF01488.20 CEG49089.1 - 0.03 14.4 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cons_hypoth95 PF03602.15 CEG49089.1 - 0.065 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DOT1 PF08123.13 CEG49089.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 CEG49089.1 - 0.098 13.7 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CEG49089.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 ASF1_hist_chap PF04729.13 CEG49090.1 - 1e-67 226.9 0.0 1.6e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Aminotran_1_2 PF00155.21 CEG49093.1 - 8.7e-43 146.9 0.0 1.3e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DapB_C PF05173.14 CEG49093.1 - 5.6e-29 100.6 0.0 1.3e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus Aminotran_MocR PF12897.7 CEG49093.1 - 4.8e-10 38.8 0.0 5.9e-09 35.2 0.0 2.3 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase DapB_N PF01113.20 CEG49093.1 - 3.8e-07 30.3 0.1 1.6e-05 25.0 0.1 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Beta_elim_lyase PF01212.21 CEG49093.1 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C3HC4_3 PF13920.6 CEG49094.1 - 1.8e-09 37.3 14.1 1.8e-09 37.3 14.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG49094.1 - 1.5e-05 24.7 12.7 3.8e-05 23.5 12.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 WD40 PF00400.32 CEG49094.1 - 3.8e-05 24.4 0.1 0.15 13.0 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Cdd1 PF11731.8 CEG49094.1 - 0.0083 16.4 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 1 Pathogenicity locus Phage_antitermQ PF06530.12 CEG49094.1 - 0.12 12.3 0.2 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Phage antitermination protein Q DUF2452 PF10504.9 CEG49094.1 - 4.2 6.8 9.5 0.27 10.7 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) zf-RING_5 PF14634.6 CEG49094.1 - 4.8 7.2 14.0 13 5.8 14.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain GSHPx PF00255.19 CEG49095.1 - 2.1e-40 136.7 0.2 2.8e-40 136.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEG49095.1 - 2.2e-08 34.0 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEG49095.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin Peroxidase_2 PF01328.17 CEG49096.1 - 1.7e-29 103.7 0.0 2.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 ATP_synth_reg PF14960.6 CEG49101.1 - 1.1 8.8 5.1 4.5 6.8 0.3 2.4 2 0 0 2 2 2 0 ATP synthase regulation Dimer_Tnp_hAT PF05699.14 CEG49104.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Xpo1 PF08389.12 CEG49106.1 - 1.3e-11 44.8 9.8 5.5e-11 42.7 0.1 5.2 4 2 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 CEG49106.1 - 6.6e-09 35.6 1.0 1.2e-07 31.5 0.2 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain zf-RING_2 PF13639.6 CEG49107.1 - 4.5e-10 39.7 5.9 4.5e-10 39.7 5.9 4.9 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEG49107.1 - 1.2e-07 31.4 4.8 1.2e-07 31.4 4.8 4.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG49107.1 - 1.3e-07 31.4 1.6 1.3e-07 31.4 1.6 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG49107.1 - 2.9e-07 30.2 4.1 2.9e-07 30.2 4.1 3.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG49107.1 - 2e-06 28.0 7.4 2e-06 28.0 7.4 4.7 2 2 2 4 4 4 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEG49107.1 - 0.0011 18.9 3.9 0.0011 18.9 3.9 4.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 CEG49107.1 - 0.0081 15.9 5.5 0.0081 15.9 5.5 3.5 3 1 0 3 3 3 1 RING-like zinc finger TCR PF03638.15 CEG49107.1 - 0.016 15.5 17.5 0.016 15.5 17.5 4.0 3 1 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Mg_trans_NIPA PF05653.14 CEG49111.1 - 4.2e-36 124.6 18.1 4.3e-35 121.3 18.1 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEG49111.1 - 0.0011 19.2 5.7 0.0011 19.2 5.7 3.4 2 1 0 3 3 3 1 EamA-like transporter family Fz PF01392.22 CEG49111.1 - 0.019 15.6 3.4 0.037 14.7 3.4 1.4 1 0 0 1 1 1 0 Fz domain TMEM234 PF10639.9 CEG49111.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.2 2 0 0 2 2 2 0 Putative transmembrane family 234 TMEM220 PF15071.6 CEG49111.1 - 0.37 11.6 6.2 3.9 8.3 0.0 3.5 3 2 0 3 3 3 0 Transmembrane family 220, helix DUF2304 PF10066.9 CEG49111.1 - 2.5 8.4 15.0 0.044 14.0 2.8 3.3 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) Aa_trans PF01490.18 CEG49112.1 - 1.7e-53 181.8 30.2 2.2e-53 181.5 30.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG49112.1 - 0.13 11.2 27.8 0.43 9.6 27.8 1.7 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family DUF1240 PF06836.12 CEG49112.1 - 4.1 8.0 12.3 0.35 11.4 1.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) Peptidase_S9 PF00326.21 CEG49113.1 - 1.5e-24 86.6 0.0 1.1e-23 83.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 CEG49113.1 - 1e-09 38.1 0.0 0.006 16.5 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 CEG49113.1 - 1.6e-07 31.2 0.7 1.7e-05 24.6 0.6 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEG49113.1 - 0.00023 20.5 0.0 0.001 18.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 CEG49113.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.28 CEG49113.1 - 0.011 14.6 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.13 CEG49113.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DNA_pol_E_B PF04042.16 CEG49114.1 - 5.3e-36 124.0 0.0 9.1e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CEG49114.1 - 2.6e-31 108.4 0.2 4.2e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF1414 PF07208.11 CEG49118.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) DUF4440 PF14534.6 CEG49119.1 - 0.16 12.4 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MoCF_biosynth PF00994.24 CEG49121.1 - 6.1e-27 94.0 0.0 9.9e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ge1_WD40 PF16529.5 CEG49122.1 - 9.5e-14 51.1 0.0 5.8e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CEG49122.1 - 0.011 16.6 0.2 2.1 9.4 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat CelTOS PF18659.1 CEG49122.1 - 0.019 15.4 1.3 7.6 7.0 0.0 3.6 3 0 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites Ints3 PF10189.9 CEG49122.1 - 0.086 12.1 0.1 0.39 9.9 0.1 2.1 1 1 0 1 1 1 0 Integrator complex subunit 3 DUF445 PF04286.12 CEG49122.1 - 0.19 11.5 5.4 0.4 10.4 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Matrilin_ccoil PF10393.9 CEG49122.1 - 0.35 10.8 1.8 0.67 9.9 0.6 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DELLA PF12041.8 CEG49122.1 - 0.36 10.7 1.4 0.91 9.5 0.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal DUF1690 PF07956.11 CEG49122.1 - 3.2 8.2 4.7 2.3 8.6 0.9 2.4 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) MbeD_MobD PF04899.12 CEG49122.1 - 4.3 7.5 6.1 0.55 10.4 0.4 2.5 2 0 0 2 2 2 0 MbeD/MobD like Aminotran_1_2 PF00155.21 CEG49126.1 - 7.2e-78 262.3 0.0 1.1e-77 261.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEG49126.1 - 8.9e-06 24.5 0.0 1.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEG49126.1 - 0.00023 20.2 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 CEG49126.1 - 0.077 13.5 6.4 0.17 12.4 6.4 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence ArsA_ATPase PF02374.15 CEG49130.1 - 6.2e-115 383.6 0.1 7.1e-115 383.4 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CEG49130.1 - 3.4e-14 53.2 0.1 8.7e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CEG49130.1 - 2.6e-13 50.1 0.1 9e-13 48.4 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CEG49130.1 - 2.7e-07 30.3 2.0 5.7e-05 22.7 0.2 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CEG49130.1 - 9.5e-07 28.5 0.0 2.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CEG49130.1 - 2.9e-06 27.0 0.0 0.00022 20.8 0.0 2.3 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CEG49130.1 - 4.7e-05 23.1 0.1 0.00063 19.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CEG49130.1 - 0.011 15.4 0.4 0.061 12.9 0.4 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CEG49130.1 - 0.011 15.2 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 CEG49130.1 - 0.048 12.8 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 CEG49130.1 - 0.057 13.1 0.1 0.23 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CEG49130.1 - 0.094 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CEG49130.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 CEG49130.1 - 0.17 11.2 0.3 0.5 9.6 0.3 1.9 1 1 0 1 1 1 0 ATPase MipZ DUF572 PF04502.13 CEG49131.1 - 1.6e-74 251.6 12.6 1.6e-74 251.6 12.6 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) PA26 PF04636.13 CEG49131.1 - 0.2 10.5 3.2 0.31 9.9 3.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) zf-FCS PF06467.14 CEG49131.1 - 0.57 10.2 4.1 19 5.3 0.1 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Terminase_2 PF03592.16 CEG49131.1 - 1.1 9.7 6.7 0.58 10.6 4.3 1.7 1 1 1 2 2 2 0 Terminase small subunit zf-CW PF07496.15 CEG49132.1 - 1.7e-43 146.4 45.6 5.3e-17 61.6 9.3 4.0 4 0 0 4 4 4 3 CW-type Zinc Finger PHD PF00628.29 CEG49132.1 - 4e-08 33.0 3.3 4e-08 33.0 3.3 6.2 5 1 0 5 5 5 2 PHD-finger CT_C_D PF02682.16 CEG49132.1 - 0.016 15.0 0.8 0.055 13.2 0.1 2.2 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D zf-rbx1 PF12678.7 CEG49132.1 - 1 9.7 19.1 0.65 10.3 4.4 3.4 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG49132.1 - 5 7.5 25.0 0.69 10.3 3.9 3.1 2 0 0 2 2 2 0 Ring finger domain Cellulose_synt PF03552.14 CEG49132.1 - 5.8 5.3 6.1 9.9 4.5 6.1 1.3 1 0 0 1 1 1 0 Cellulose synthase DUF1664 PF07889.12 CEG49135.1 - 0.0042 17.1 0.7 0.0042 17.1 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Prp19 PF08606.11 CEG49135.1 - 0.0063 16.5 0.8 0.0063 16.5 0.8 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like GAS PF13851.6 CEG49135.1 - 0.012 14.9 2.2 0.012 14.9 2.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 CEG49135.1 - 0.022 15.2 1.6 0.022 15.2 1.6 2.2 2 2 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 CEG49135.1 - 0.032 13.1 10.2 0.073 11.9 10.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CEG49135.1 - 0.04 14.0 18.9 0.35 11.0 8.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CEG49135.1 - 0.072 13.5 1.5 0.072 13.5 1.5 2.4 2 1 0 2 2 2 0 Cell division protein ZapB MctB PF11382.8 CEG49135.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB FAM76 PF16046.5 CEG49135.1 - 0.084 12.2 5.5 0.12 11.7 5.5 1.2 1 0 0 1 1 1 0 FAM76 protein EMP24_GP25L PF01105.24 CEG49135.1 - 0.17 11.8 3.1 0.24 11.4 3.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SLX9 PF15341.6 CEG49135.1 - 0.17 12.3 8.1 0.25 11.7 8.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 TolA_bind_tri PF16331.5 CEG49135.1 - 0.23 11.5 13.3 5.6 7.1 0.5 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation Atg14 PF10186.9 CEG49135.1 - 0.42 9.7 9.8 1.8 7.6 10.2 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 CEG49135.1 - 0.52 8.2 2.7 0.61 8.0 2.7 1.0 1 0 0 1 1 1 0 Prominin Noelin-1 PF12308.8 CEG49135.1 - 0.66 10.0 4.8 0.17 11.9 0.5 1.9 2 0 0 2 2 2 0 Neurogenesis glycoprotein bZIP_2 PF07716.15 CEG49135.1 - 1.3 9.2 24.1 0.16 12.0 12.4 2.7 2 2 0 2 2 2 0 Basic region leucine zipper TssO PF17561.2 CEG49135.1 - 1.4 9.0 6.1 3.3 7.8 6.1 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssO FapA PF03961.13 CEG49135.1 - 2 6.9 5.6 2.5 6.6 5.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF724 PF05266.14 CEG49135.1 - 2.3 8.0 11.0 0.68 9.7 1.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.12 CEG49135.1 - 3.4 8.4 9.9 0.24 12.1 2.6 2.4 2 1 1 3 3 3 0 SlyX CCDC-167 PF15188.6 CEG49135.1 - 6.9 7.1 11.4 5.4 7.4 3.4 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ccdc124 PF06244.12 CEG49138.1 - 1.1e-27 97.1 32.0 4.7e-27 95.1 25.8 2.7 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CEG49138.1 - 0.0021 18.4 0.2 0.0021 18.4 0.2 3.1 2 1 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.12 CEG49138.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF3889 PF13028.6 CEG49138.1 - 0.031 14.2 0.1 0.031 14.2 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3889) AAA_15 PF13175.6 CEG49138.1 - 0.26 11.0 4.9 0.31 10.7 4.9 1.2 1 0 0 1 1 1 0 AAA ATPase domain cNMP_binding PF00027.29 CEG49139.1 - 7.7e-43 144.5 0.0 3.2e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EF-hand_14 PF17959.1 CEG49139.1 - 0.046 14.1 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Proteasome PF00227.26 CEG49140.1 - 1.7e-26 92.9 0.4 5.2e-26 91.3 0.4 1.7 1 1 0 1 1 1 1 Proteasome subunit DUF974 PF06159.13 CEG49141.1 - 2.9e-53 181.2 0.0 1.7e-52 178.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 CEG49141.1 - 0.015 14.7 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 KNOX2 PF03791.13 CEG49142.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 KNOX2 domain Thioredoxin_8 PF13905.6 CEG49144.1 - 2.8e-27 94.9 0.0 7.9e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Ribosomal_L22 PF00237.19 CEG49144.1 - 3.3e-26 91.5 0.5 6.8e-26 90.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Thioredoxin PF00085.20 CEG49144.1 - 7.4e-08 32.3 0.0 3.2e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CEG49144.1 - 8e-08 32.7 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 CEG49144.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEG49144.1 - 5.3e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 CEG49144.1 - 0.0037 17.0 0.0 0.065 13.0 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEG49144.1 - 0.023 14.9 0.0 0.069 13.3 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 CEG49144.1 - 0.12 11.7 0.1 0.83 8.9 0.0 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family PDZ_6 PF17820.1 CEG49145.1 - 4e-11 42.6 0.0 8.6e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ZZ PF00569.17 CEG49145.1 - 4.3e-10 39.2 3.1 8.9e-10 38.2 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PDZ PF00595.24 CEG49145.1 - 1e-05 25.8 0.0 3.6e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CEG49145.1 - 0.0025 18.1 0.0 0.0087 16.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CEG49145.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF4611 PF15387.6 CEG49145.1 - 2.5 8.3 12.8 0.11 12.7 3.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Syntaxin_2 PF14523.6 CEG49146.1 - 1.4e-17 63.9 11.8 3e-17 62.8 4.6 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 CEG49146.1 - 2.2e-06 27.5 14.6 3.7e-06 26.8 10.5 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 CEG49146.1 - 0.0014 18.6 5.2 0.0043 17.0 5.2 1.9 1 1 0 1 1 1 1 SNARE domain Dynein_C PF18199.1 CEG49146.1 - 0.031 13.5 0.1 0.053 12.7 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Synaptobrevin PF00957.21 CEG49146.1 - 0.054 13.3 0.6 0.054 13.3 0.6 2.4 2 1 1 3 3 3 0 Synaptobrevin COG2 PF06148.11 CEG49146.1 - 0.098 12.7 4.3 0.98 9.5 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4665 PF15679.5 CEG49146.1 - 0.23 12.1 6.8 1.4 9.6 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) YtxH PF12732.7 CEG49146.1 - 0.25 11.9 4.2 7.4 7.2 0.3 2.9 2 1 1 3 3 3 0 YtxH-like protein WXG100 PF06013.12 CEG49146.1 - 0.65 10.3 4.8 12 6.2 0.1 3.7 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Sec8_exocyst PF04048.14 CEG49146.1 - 2.8 7.8 8.6 1.6 8.6 0.4 3.4 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF4537 PF15057.6 CEG49147.1 - 1.3e-05 25.2 3.5 0.19 11.8 0.0 4.8 4 1 1 5 5 5 2 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 CEG49147.1 - 3.6e-05 23.7 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor Tudor_2 PF18104.1 CEG49147.1 - 0.00066 19.3 3.6 0.63 9.8 0.1 4.5 4 0 0 4 4 4 1 Jumonji domain-containing protein 2A Tudor domain DUF1325 PF07039.11 CEG49147.1 - 0.00086 19.4 0.7 1.5 9.0 0.1 3.4 3 0 0 3 3 3 2 SGF29 tudor-like domain LBR_tudor PF09465.10 CEG49147.1 - 0.003 17.3 0.2 0.081 12.7 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain SpvB PF03534.13 CEG49147.1 - 0.04 13.1 0.3 0.091 11.9 0.0 1.7 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein TUDOR_5 PF18359.1 CEG49147.1 - 0.56 10.0 6.4 0.081 12.6 1.2 2.3 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 Tubulin PF00091.25 CEG49149.1 - 1.1e-40 139.9 0.0 5.7e-38 131.1 0.0 3.4 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CEG49149.1 - 0.0006 19.1 0.0 0.00096 18.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CEG49149.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain CYTH PF01928.21 CEG49152.1 - 0.064 13.2 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 CYTH domain Myb_DNA-binding PF00249.31 CEG49156.1 - 2.1e-11 43.8 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG49156.1 - 0.096 12.9 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Kinesin PF00225.23 CEG49157.1 - 3.3e-117 391.1 1.4 3.4e-117 391.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG49157.1 - 1.6e-26 93.1 0.0 5.4e-26 91.3 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CEG49157.1 - 0.26 11.4 17.2 2.1 8.5 12.3 3.3 2 1 0 2 2 2 0 Kinesin-associated AAA_16 PF13191.6 CEG49157.1 - 0.35 11.2 0.0 0.35 11.2 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CEG49157.1 - 3.7 7.8 5.6 4.4 7.6 0.0 3.3 2 1 2 4 4 4 0 AAA domain AAA PF00004.29 CEG49158.1 - 3.1e-09 37.4 0.0 1.2e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEG49158.1 - 5.2e-09 36.7 0.0 1.7e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG49158.1 - 2.8e-07 30.9 0.0 1.6e-06 28.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CEG49158.1 - 1.9e-05 24.2 0.0 4.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein Ferritin PF00210.24 CEG49158.1 - 0.00045 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 Ferritin-like domain ATPase_2 PF01637.18 CEG49158.1 - 0.00052 20.0 0.1 0.0059 16.5 0.1 2.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CEG49158.1 - 0.0063 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Cdc6_C PF09079.11 CEG49158.1 - 0.014 15.4 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PWWP PF00855.17 CEG49158.1 - 0.089 13.2 0.3 0.33 11.4 0.3 2.1 1 1 0 1 1 1 0 PWWP domain Bac_DnaA PF00308.18 CEG49158.1 - 0.096 12.5 0.0 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein DUF4549 PF15082.6 CEG49158.1 - 0.27 11.0 1.3 0.68 9.7 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Ank_2 PF12796.7 CEG49159.1 - 5e-41 139.2 11.2 4e-14 53.0 0.1 5.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG49159.1 - 1.1e-32 108.4 8.6 4.7e-05 23.5 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 CEG49159.1 - 2.3e-32 110.9 2.3 8.2e-08 32.6 0.0 6.7 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 CEG49159.1 - 1.4e-27 94.9 12.2 2.3e-06 27.8 0.1 8.7 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 CEG49159.1 - 6.2e-25 86.9 3.2 1.3e-05 25.4 0.0 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) vATP-synt_E PF01991.18 CEG49159.1 - 0.036 13.5 0.2 0.096 12.1 0.2 1.6 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Ribonuc_red_sm PF00268.21 CEG49162.1 - 4.1e-101 338.1 1.1 3.4e-81 272.8 0.4 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, small chain PX PF00787.24 CEG49163.1 - 9.8e-07 28.8 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PX domain TPR_2 PF07719.17 CEG49164.1 - 2.3e-36 121.0 24.4 0.00034 20.5 0.4 13.2 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_19 PF14559.6 CEG49164.1 - 1.4e-31 108.8 11.3 5.9e-07 29.9 0.0 10.0 5 4 6 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49164.1 - 7.7e-31 106.5 0.4 2.1e-07 31.5 0.1 7.6 5 1 2 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CEG49164.1 - 1.3e-28 97.6 35.7 0.00084 19.1 0.0 13.3 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49164.1 - 6.1e-26 88.9 4.5 0.03 15.1 0.0 10.8 6 4 4 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49164.1 - 1e-22 78.4 12.9 0.003 17.5 0.0 10.1 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEG49164.1 - 1.1e-21 75.1 21.3 0.0014 18.7 0.0 11.1 12 0 0 12 12 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG49164.1 - 1.1e-20 73.6 18.0 4.3e-06 26.9 0.0 6.3 4 1 1 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CEG49164.1 - 1.5e-19 70.1 19.3 0.00039 20.6 0.1 9.3 7 3 2 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49164.1 - 1.7e-18 66.0 20.1 0.0015 18.2 1.1 12.4 9 3 4 13 13 13 5 TPR repeat TPR_17 PF13431.6 CEG49164.1 - 7.3e-17 60.5 22.1 0.18 12.3 0.0 13.4 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49164.1 - 9e-15 54.3 28.6 0.25 12.1 0.0 11.9 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG49164.1 - 1.1e-12 47.3 14.2 0.26 11.2 0.0 9.3 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEG49164.1 - 8.5e-09 35.4 1.1 3.6 7.8 0.0 6.6 3 3 4 7 7 7 1 Tetratricopeptide repeat YfiO PF13525.6 CEG49164.1 - 4.7e-06 26.5 4.0 0.13 11.9 0.2 3.7 3 0 0 3 3 3 2 Outer membrane lipoprotein TPR_15 PF13429.6 CEG49164.1 - 3.7e-05 23.1 2.2 0.062 12.5 0.0 4.6 2 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 CEG49164.1 - 0.0085 15.1 0.1 0.31 10.0 0.0 2.9 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 CEG49164.1 - 0.034 14.1 8.2 1.8 8.6 0.4 4.7 4 1 0 4 4 4 0 Putative TPR-like repeat MIT PF04212.18 CEG49164.1 - 0.052 13.6 16.0 17 5.6 0.2 6.5 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain HrpB1_HrpK PF09613.10 CEG49164.1 - 0.065 12.9 0.2 24 4.6 0.0 4.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 CEG49164.1 - 0.11 13.1 0.0 40 5.2 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEG49164.1 - 8.9 6.4 27.2 8.7 6.4 0.2 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 CEG49165.1 - 0.016 15.6 0.5 0.26 11.7 0.0 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain AvrPto PF11592.8 CEG49165.1 - 0.016 15.2 0.1 0.12 12.5 0.1 2.4 1 1 1 2 2 2 0 Central core of the bacterial effector protein AvrPto LRR_6 PF13516.6 CEG49166.1 - 2.7e-08 33.2 17.1 0.85 9.8 0.1 7.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 CEG49166.1 - 6.9e-05 22.9 5.9 2.7 8.9 0.0 6.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 CEG49166.1 - 0.0031 17.3 12.5 0.46 10.3 2.8 6.4 5 1 2 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 CEG49166.1 - 0.028 14.8 12.8 0.094 13.2 0.2 5.5 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) UPF0561 PF10573.9 CEG49166.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 XRN_M PF17846.1 CEG49166.1 - 0.16 10.9 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Xrn1 helical domain RRM_1 PF00076.22 CEG49167.1 - 1.2e-22 79.5 0.0 1.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEG49167.1 - 0.00025 20.6 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG49167.1 - 0.0051 16.9 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif ATP-synt_C PF00137.21 CEG49168.1 - 9.2e-16 57.9 21.3 2e-12 47.2 10.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SET PF00856.28 CEG49169.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.8 1 1 0 1 1 1 0 SET domain Bac_surface_Ag PF01103.23 CEG49170.1 - 1.5e-42 146.2 0.7 1.9e-42 145.9 0.7 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 CEG49170.1 - 8.9e-05 23.0 0.4 0.00017 22.1 0.4 1.5 1 0 0 1 1 1 1 Surface antigen variable number repeat GTPase_binding PF09027.10 CEG49170.1 - 0.04 13.9 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 GTPase binding PCC_BT PF18140.1 CEG49172.1 - 0.02 15.3 1.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain ChaC PF04752.12 CEG49173.1 - 2.2e-53 180.9 0.0 2.6e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 CEG49173.1 - 4.6e-05 24.0 0.1 8.3e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CEG49173.1 - 0.00021 21.7 0.0 0.00033 21.0 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family PRA1 PF03208.19 CEG49174.1 - 2.5e-18 66.1 0.0 2.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 PRA1 family protein TraL PF07178.11 CEG49174.1 - 0.071 13.6 0.2 0.69 10.4 0.1 2.0 2 0 0 2 2 2 0 TraL protein Vfa1 PF08432.10 CEG49175.1 - 0.017 15.5 0.6 0.021 15.1 0.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 vWF_A PF12450.8 CEG49175.1 - 0.079 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor GTP_EFTU PF00009.27 CEG49176.1 - 8e-52 175.6 0.1 1.3e-51 174.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CEG49176.1 - 9.8e-22 76.8 0.0 2.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus HEAT PF02985.22 CEG49176.1 - 1.3e-08 34.4 24.6 0.02 15.1 0.0 10.1 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 CEG49176.1 - 1.3e-08 35.1 9.7 0.057 13.8 0.1 7.4 5 3 1 6 6 6 3 HEAT repeats GTP_EFTU_D2 PF03144.25 CEG49176.1 - 2.6e-08 34.1 1.5 5.9e-08 33.0 1.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Vac14_Fab1_bd PF12755.7 CEG49176.1 - 5.4e-08 33.3 0.4 2.2 8.9 0.1 5.9 5 2 2 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEG49176.1 - 7.8e-07 29.3 3.6 0.29 11.1 0.0 4.4 4 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEG49176.1 - 8.9e-07 29.3 12.6 0.24 12.0 0.0 7.7 7 0 0 7 7 7 1 HEAT-like repeat MMR_HSR1 PF01926.23 CEG49176.1 - 1.3e-06 28.5 0.1 2.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase CLASP_N PF12348.8 CEG49176.1 - 2e-05 24.2 0.3 0.16 11.5 0.0 4.2 5 0 0 5 5 5 2 CLASP N terminal Septin PF00735.18 CEG49176.1 - 0.011 15.1 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 CEG49176.1 - 0.019 14.4 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CEG49176.1 - 0.022 14.7 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase EFG_II PF14492.6 CEG49176.1 - 0.056 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II FeoB_N PF02421.18 CEG49176.1 - 0.089 12.3 0.1 0.37 10.3 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 CEG49176.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma70_r1_1 PF03979.14 CEG49178.1 - 0.01 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Tup_N PF08581.10 CEG49179.1 - 0.031 14.6 4.2 0.054 13.8 4.2 1.3 1 0 0 1 1 1 0 Tup N-terminal SlyX PF04102.12 CEG49179.1 - 0.12 13.0 4.3 0.28 11.8 4.3 1.7 1 0 0 1 1 1 0 SlyX DUF4094 PF13334.6 CEG49179.1 - 0.21 12.0 1.7 0.58 10.6 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) IQ PF00612.27 CEG49180.1 - 5.7e-15 53.6 36.5 0.00046 19.7 0.1 10.1 10 0 0 10 10 10 6 IQ calmodulin-binding motif TPR_1 PF00515.28 CEG49180.1 - 5.3e-12 45.0 11.3 4.2e-05 23.2 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49180.1 - 2.1e-09 37.5 11.7 0.00014 22.1 0.8 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49180.1 - 1.6e-07 30.9 11.4 0.0003 20.7 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEG49180.1 - 2.5e-06 27.1 9.3 0.021 14.7 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEG49180.1 - 0.00038 20.4 8.4 0.0076 16.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49180.1 - 0.0018 18.2 6.6 0.069 13.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat CompInhib_SCIN PF11546.8 CEG49180.1 - 3.2 7.8 7.4 0.66 10.0 0.2 3.2 4 0 0 4 4 4 0 Staphylococcal complement inhibitor SCIN ThiF PF00899.21 CEG49181.1 - 5.5e-48 163.5 0.1 7.8e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 CEG49181.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEG49181.1 - 0.0037 16.9 0.3 0.015 14.9 0.1 1.9 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CEG49181.1 - 0.0046 17.4 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.16 CEG49181.1 - 0.043 13.4 0.5 0.19 11.4 0.5 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CEG49181.1 - 0.053 12.8 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain AceK PF06315.11 CEG49181.1 - 0.056 11.9 0.0 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) TrkA_N PF02254.18 CEG49181.1 - 0.086 13.1 0.1 5 7.4 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CEG49181.1 - 0.94 9.7 6.0 7.6 6.8 3.6 2.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KIX_2 PF16987.5 CEG49182.1 - 1.8e-11 43.8 0.1 4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 KIX domain AChE_tetra PF08674.10 CEG49183.1 - 0.082 12.6 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Rib_5-P_isom_A PF06026.14 CEG49184.1 - 2.5e-63 212.8 0.0 3.1e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 CEG49184.1 - 0.068 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Torus PF16131.5 CEG49185.1 - 2.5e-16 60.3 16.4 0.0013 19.4 0.4 4.4 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 CEG49185.1 - 3.2e-12 46.0 36.3 1.1e-05 25.3 0.3 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG49185.1 - 9.2e-11 41.4 43.2 2.5e-05 24.1 1.1 4.8 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 CEG49185.1 - 4.2e-10 39.2 39.2 0.0068 16.2 0.5 4.8 4 0 0 4 4 4 4 CCCH-type zinc finger zf-C3HC4 PF00097.25 CEG49185.1 - 2.3e-08 33.8 6.9 6.1e-08 32.4 6.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG49185.1 - 1.1e-07 32.0 7.2 1.1e-07 32.0 7.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_3 PF15663.5 CEG49185.1 - 2.8e-06 27.5 12.6 0.031 14.5 1.1 4.1 4 0 0 4 4 4 2 Zinc-finger containing family zf-RING_5 PF14634.6 CEG49185.1 - 2.9e-06 27.1 7.5 2.9e-06 27.1 7.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEG49185.1 - 6.8e-06 25.9 5.3 1.8e-05 24.5 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG49185.1 - 3.2e-05 23.8 3.7 3.6e-05 23.7 1.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG49185.1 - 0.00014 21.7 5.4 0.00063 19.5 5.4 2.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG49185.1 - 0.0096 16.2 7.8 0.044 14.1 7.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CEG49185.1 - 0.016 15.4 3.8 0.062 13.5 3.8 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEG49185.1 - 0.031 14.1 9.7 0.41 10.5 9.7 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEG49185.1 - 0.091 12.8 5.0 0.22 11.6 1.5 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEG49185.1 - 0.28 11.0 8.2 0.086 12.6 3.3 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 CEG49185.1 - 0.75 10.0 5.1 0.31 11.2 1.9 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger Cpn60_TCP1 PF00118.24 CEG49186.1 - 4.9e-150 500.4 0.5 5.6e-150 500.2 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2121 PF09894.9 CEG49186.1 - 0.026 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Beta_helix_2 PF18835.1 CEG49186.1 - 0.091 12.5 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase ATP-gua_Ptrans PF00217.19 CEG49187.1 - 2.2e-75 252.8 0.0 3.2e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CEG49187.1 - 5.3e-29 100.4 0.0 9.4e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Ribosomal_L20 PF00453.18 CEG49188.1 - 1.2e-40 137.9 2.0 1.4e-40 137.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 SpoIIE PF07228.12 CEG49189.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CEG49189.1 - 2.4e-05 24.1 0.1 0.046 13.3 0.0 2.5 2 1 1 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 CEG49189.1 - 0.0057 16.3 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C YHYH PF14240.6 CEG49190.1 - 1e-29 103.9 0.4 5.3e-16 59.1 0.0 4.6 2 2 2 4 4 4 4 YHYH protein DUF4923 PF16270.5 CEG49190.1 - 0.18 11.6 0.2 5.2 6.9 0.0 3.0 2 0 0 2 2 2 0 Lipocalin-like domain (DUF4923) NadA PF02445.16 CEG49191.1 - 5.4e-33 114.4 0.2 1.5e-31 109.6 0.2 2.1 2 0 0 2 2 2 1 Quinolinate synthetase A protein Reprolysin_5 PF13688.6 CEG49191.1 - 0.029 14.5 0.1 0.051 13.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 MRP-S33 PF08293.11 CEG49191.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Aldedh PF00171.22 CEG49192.1 - 1.7e-06 26.9 0.1 1.7e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 CEG49194.1 - 1.4e-22 80.1 4.3 5.6e-11 42.9 0.7 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG49194.1 - 2e-17 61.5 1.0 0.006 17.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CEG49194.1 - 5e-17 62.0 4.3 1.7e-09 38.0 0.5 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG49194.1 - 4.3e-14 52.4 3.0 0.00011 22.4 0.1 4.9 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CEG49194.1 - 6.5e-11 42.2 7.2 3e-05 24.3 0.4 4.7 5 0 0 5 5 5 2 Ankyrin repeat CTP_synth_N PF06418.14 CEG49195.1 - 2.8e-124 413.7 0.1 4e-124 413.2 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CEG49195.1 - 1.6e-54 184.6 0.0 2.5e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEG49195.1 - 0.055 13.2 0.7 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 Peptidase C26 MeaB PF03308.16 CEG49195.1 - 0.2 10.6 0.6 0.53 9.2 0.6 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-B_box PF00643.24 CEG49196.1 - 1.3e-12 47.7 25.0 1.1e-07 31.9 2.8 3.0 3 0 0 3 3 3 2 B-box zinc finger IBR PF01485.21 CEG49196.1 - 0.0055 16.9 14.9 0.015 15.5 2.0 3.0 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain PARP PF00644.20 CEG49196.1 - 0.044 13.4 0.3 0.26 10.8 0.3 2.3 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain MbeB_N PF04837.12 CEG49196.1 - 0.15 12.3 1.2 0.66 10.3 1.2 2.2 1 0 0 1 1 1 0 MbeB-like, N-term conserved region CEBP_ZZ PF16366.5 CEG49196.1 - 0.27 11.5 12.0 0.27 11.5 5.0 2.6 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_4 PF07975.12 CEG49196.1 - 7.6 6.9 13.2 10 6.4 4.0 3.1 2 0 0 2 2 2 0 TFIIH C1-like domain TAXi_N PF14543.6 CEG49197.1 - 2.7e-25 89.6 2.9 2.7e-25 89.6 2.9 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 CEG49197.1 - 2e-22 80.0 3.7 1e-21 77.7 3.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CEG49197.1 - 2.7e-09 37.0 0.0 9.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TMEM51 PF15345.6 CEG49197.1 - 0.021 14.7 0.2 0.021 14.7 0.2 2.3 2 1 1 3 3 3 0 Transmembrane protein 51 EphA2_TM PF14575.6 CEG49197.1 - 0.065 14.1 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CRA PF06589.11 CEG49197.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) LapA_dom PF06305.11 CEG49197.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Serinc PF03348.15 CEG49197.1 - 1 8.2 4.0 0.23 10.3 0.5 1.6 1 1 1 2 2 2 0 Serine incorporator (Serinc) Plasmodium_Vir PF05795.11 CEG49197.1 - 1.3 8.4 8.3 1.4 8.3 6.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4834 PF16118.5 CEG49197.1 - 1.9 9.5 4.2 0.82 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Asp PF00026.23 CEG49198.1 - 1.6e-27 96.8 0.7 5.5e-19 68.7 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEG49198.1 - 3.2e-21 76.3 0.9 5.5e-21 75.6 0.9 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEG49198.1 - 1.5e-07 31.3 0.0 6.8e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RHSP PF07999.11 CEG49201.1 - 0.066 12.0 0.6 0.46 9.3 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon hot spot protein Exonuc_VII_S PF02609.16 CEG49201.1 - 0.23 11.6 1.0 5.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Methyltr_RsmB-F PF01189.17 CEG49202.1 - 4.1e-30 104.9 0.0 8.8e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CEG49202.1 - 7.8e-06 26.5 0.3 0.00028 21.6 0.1 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG49202.1 - 0.0004 20.2 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 CEG49202.1 - 0.00079 19.6 0.1 0.0054 16.9 0.1 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 CEG49202.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CEG49202.1 - 0.044 13.6 0.1 0.38 10.6 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CEG49202.1 - 0.053 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MAR_sialic_bdg PF10564.9 CEG49202.1 - 0.07 13.2 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Methyltransf_11 PF08241.12 CEG49202.1 - 0.085 13.5 0.1 2.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain ANAPC4_WD40 PF12894.7 CEG49203.1 - 1.1e-11 44.9 2.1 2e-05 24.8 0.1 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CEG49203.1 - 7e-08 31.9 3.8 0.00023 20.4 0.0 4.5 4 1 1 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 CEG49203.1 - 0.00016 21.4 3.4 0.89 9.7 0.0 5.7 4 2 1 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.20 CEG49203.1 - 0.00067 19.5 3.8 0.045 13.6 0.1 4.3 2 1 2 4 4 4 1 Region in Clathrin and VPS TPR_14 PF13428.6 CEG49203.1 - 0.0011 19.7 9.1 17 6.6 0.2 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEG49203.1 - 0.0028 17.4 8.3 0.075 12.9 0.2 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat WD40 PF00400.32 CEG49203.1 - 0.014 16.2 6.2 2.6 9.1 0.0 5.7 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_12 PF13424.6 CEG49203.1 - 0.021 15.1 8.7 0.74 10.1 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49203.1 - 0.024 14.7 22.1 0.033 14.3 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG49203.1 - 0.047 13.9 12.6 1.7 8.9 0.7 5.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps16_N PF04841.13 CEG49203.1 - 0.099 11.4 0.2 1.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Vps16, N-terminal region PD40 PF07676.12 CEG49203.1 - 0.18 11.8 0.1 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TPR_8 PF13181.6 CEG49203.1 - 0.47 10.8 6.3 11 6.5 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49203.1 - 7.2 7.5 5.3 1.2e+02 3.6 0.3 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DZR PF12773.7 CEG49203.1 - 8 6.6 17.9 0.51 10.4 3.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon TPR_19 PF14559.6 CEG49203.1 - 8.8 6.9 17.4 2 9.0 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat FUSC PF04632.12 CEG49204.1 - 0.34 9.4 2.5 0.56 8.7 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PPR_3 PF13812.6 CEG49205.1 - 2.5e-14 53.1 5.2 5.4e-05 23.2 0.0 7.8 6 2 3 9 9 9 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 CEG49205.1 - 1e-13 51.3 5.4 0.00035 20.7 0.0 8.2 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.20 CEG49205.1 - 3.8e-12 45.6 4.4 0.34 11.2 0.0 9.1 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 CEG49205.1 - 3e-09 36.6 6.8 0.033 13.6 0.0 5.3 4 2 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP Retrotran_gag_2 PF14223.6 CEG49207.1 - 7.6e-05 22.4 0.1 9.5e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ribosomal_L28e PF01778.17 CEG49210.1 - 3.6e-14 53.5 2.6 4.6e-14 53.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Yop-YscD_cpl PF16697.5 CEG49211.1 - 5e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 CEG49211.1 - 0.00068 19.9 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF410 PF04190.13 CEG49211.1 - 0.0049 16.7 1.5 0.0098 15.7 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CENP-X PF09415.10 CEG49212.1 - 1.9e-11 44.1 1.2 3e-11 43.5 1.2 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X PfkB PF00294.24 CEG49213.1 - 3.5e-55 187.4 1.0 3.9e-55 187.3 1.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CEG49213.1 - 5.6e-11 42.3 0.1 9.6e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 CEG49213.1 - 0.0052 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate kinase zf-Di19 PF05605.12 CEG49214.1 - 0.096 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding COPIIcoated_ERV PF07970.12 CEG49216.1 - 1.2e-25 90.7 2.1 4.5e-24 85.5 0.1 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEG49216.1 - 1.1e-19 70.6 0.0 3.4e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LRR_6 PF13516.6 CEG49216.1 - 6.4e-17 60.1 14.8 2.7e-05 23.9 0.0 8.8 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 CEG49216.1 - 6.1e-10 39.2 5.6 0.045 14.2 0.1 5.9 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG49216.1 - 4.1e-05 23.3 0.0 0.33 10.7 0.0 3.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CEG49216.1 - 7.6e-05 22.7 13.3 25 5.9 0.0 8.3 8 0 0 8 8 8 0 Leucine Rich Repeat Ribosomal_TL5_C PF14693.6 CEG49216.1 - 0.032 14.6 0.3 0.087 13.2 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Adeno_E4_34 PF04528.13 CEG49216.1 - 0.21 11.4 7.5 0.1 12.5 0.8 2.7 2 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region UPF0731 PF14982.6 CEG49216.1 - 0.75 10.0 2.3 15 5.8 0.0 3.1 2 1 0 3 3 3 0 UPF0731 family Fer2_BFD PF04324.15 CEG49216.1 - 1.1 9.7 3.6 36 4.8 0.1 4.0 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain Deltameth_res PF16020.5 CEG49217.1 - 0.039 13.8 0.5 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Deltamethrin resistance Methyltransf_28 PF02636.17 CEG49218.1 - 2.2e-71 240.6 0.0 6.3e-71 239.1 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 CEG49218.1 - 0.034 14.9 0.0 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L16 PF00252.18 CEG49219.1 - 5.6e-38 129.9 0.0 7e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Apo-CIII PF05778.12 CEG49222.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Retrotran_gag_2 PF14223.6 CEG49223.1 - 1.6e-09 37.6 0.2 2.1e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RhlB PF12300.8 CEG49223.1 - 0.1 12.7 3.2 0.13 12.3 3.2 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB COG7 PF10191.9 CEG49223.1 - 0.22 9.7 0.3 0.25 9.5 0.3 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) rve PF00665.26 CEG49225.1 - 3.4e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 CEG49225.1 - 2.7e-05 23.9 0.1 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TAF4 PF05236.14 CEG49225.1 - 0.06 13.1 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RVT_2 PF07727.14 CEG49227.1 - 2.2e-05 24.3 0.3 0.041 13.5 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CEG49229.1 - 4.8e-26 91.1 0.0 5.5e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Fibrillin_U_N PF18193.1 CEG49230.1 - 0.032 14.4 0.2 0.044 13.9 0.2 1.3 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain MGC-24 PF05283.11 CEG49238.1 - 7.3 7.0 7.6 1.3 9.5 0.0 2.8 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EBA-175_VI PF11556.8 CEG49239.1 - 0.074 13.4 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 GILT PF03227.16 CEG49241.1 - 1.3e-34 118.6 1.8 1.6e-18 66.9 0.9 2.5 2 0 0 2 2 2 2 Gamma interferon inducible lysosomal thiol reductase (GILT) Redoxin PF08534.10 CEG49241.1 - 0.024 14.4 0.3 5 6.8 0.1 2.3 2 0 0 2 2 2 0 Redoxin Lung_7-TM_R PF06814.13 CEG49242.1 - 3e-41 141.6 13.2 3.7e-41 141.3 13.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Lung_7-TM_R PF06814.13 CEG49243.1 - 4.6e-29 101.6 18.2 1.4e-16 60.6 2.5 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor Ribosomal_S24e PF01282.19 CEG49245.1 - 1.7e-34 117.6 0.1 1.7e-34 117.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e ABC_tran PF00005.27 CEG49246.1 - 1.4e-48 164.9 3.0 5.3e-25 88.5 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CEG49246.1 - 5.8e-14 52.6 6.9 0.013 15.3 0.2 4.8 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG49246.1 - 7.8e-10 38.6 8.6 0.0043 16.5 0.0 4.4 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEG49246.1 - 3.5e-08 33.1 1.1 0.0043 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEG49246.1 - 2e-06 28.3 0.4 0.046 14.1 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 CEG49246.1 - 2.8e-06 27.8 0.1 0.15 12.5 0.1 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CEG49246.1 - 2.9e-06 27.9 31.5 0.00089 19.8 0.3 4.5 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 CEG49246.1 - 8.2e-06 25.8 0.1 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CEG49246.1 - 6.8e-05 23.2 1.4 0.061 13.6 0.2 3.4 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEG49246.1 - 0.00017 21.3 0.1 4.7 6.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CEG49246.1 - 0.00022 21.2 1.8 0.17 11.8 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 CEG49246.1 - 0.00024 20.9 1.1 0.2 11.3 0.4 3.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEG49246.1 - 0.00025 21.1 0.2 0.0065 16.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CEG49246.1 - 0.00029 20.6 3.9 0.12 12.1 0.1 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CEG49246.1 - 0.0006 20.2 0.0 0.46 10.9 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 CEG49246.1 - 0.00083 19.4 0.1 2.4 8.2 0.1 3.3 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.15 CEG49246.1 - 0.0016 18.4 0.2 0.75 9.7 0.3 2.7 2 0 0 2 2 2 1 NTPase Roc PF08477.13 CEG49246.1 - 0.003 17.8 0.3 1.1 9.5 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CEG49246.1 - 0.0052 16.3 0.2 2.9 7.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 CEG49246.1 - 0.006 16.3 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 CEG49246.1 - 0.0075 16.0 0.2 1.7 8.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein cobW PF02492.19 CEG49246.1 - 0.012 15.2 0.1 11 5.6 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_Xtn PF12848.7 CEG49246.1 - 0.026 14.5 0.1 0.026 14.5 0.1 4.8 5 0 0 5 5 3 0 ABC transporter RuvB_N PF05496.12 CEG49246.1 - 0.029 14.1 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_15 PF13175.6 CEG49246.1 - 0.032 13.9 0.2 0.032 13.9 0.2 4.5 2 1 2 4 4 3 0 AAA ATPase domain NB-ARC PF00931.22 CEG49246.1 - 0.039 13.1 4.1 0.56 9.4 0.3 3.1 2 1 0 2 2 2 0 NB-ARC domain Arf PF00025.21 CEG49246.1 - 0.092 12.2 0.2 18 4.7 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.6 CEG49246.1 - 0.15 12.2 9.8 0.94 9.6 0.0 4.1 4 1 0 5 5 4 0 AAA domain AAA_5 PF07728.14 CEG49246.1 - 0.59 10.1 6.0 1.8 8.6 0.1 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CEG49246.1 - 0.7 10.1 9.2 0.72 10.1 0.0 3.5 4 1 0 4 4 2 0 AAA domain AAA_18 PF13238.6 CEG49246.1 - 1.1 9.9 8.5 0.74 10.4 0.1 3.9 4 1 0 4 4 3 0 AAA domain Ndc1_Nup PF09531.10 CEG49246.1 - 1.9 7.1 6.0 2.9 6.4 6.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Elicitin PF00964.17 CEG49249.1 - 4.8e-07 29.8 0.2 1.1e-06 28.6 0.1 1.6 1 1 0 1 1 1 1 Elicitin Mito_carr PF00153.27 CEG49250.1 - 1.6e-54 181.8 5.6 9.1e-19 67.2 0.6 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_1 PF00515.28 CEG49252.1 - 1.2e-50 167.3 10.7 4.4e-07 29.4 0.0 10.4 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49252.1 - 6.6e-42 138.3 19.1 0.00022 21.1 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEG49252.1 - 1.1e-38 128.2 7.2 3.8e-05 23.5 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 CEG49252.1 - 3.1e-26 89.8 14.4 0.00056 20.1 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49252.1 - 1.1e-21 76.2 15.3 5.9e-06 25.9 0.0 10.0 6 2 4 10 10 10 4 TPR repeat TPR_14 PF13428.6 CEG49252.1 - 2.9e-18 65.0 16.2 0.016 16.0 0.0 10.0 5 2 5 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49252.1 - 5.7e-18 65.0 26.1 0.00069 19.9 0.1 8.3 5 4 2 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEG49252.1 - 1.7e-15 57.3 25.9 9.6e-06 26.0 0.0 7.2 4 1 5 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49252.1 - 3.2e-15 56.5 15.8 0.014 16.0 0.1 7.6 4 2 3 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49252.1 - 2.4e-12 46.0 7.3 0.063 13.3 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49252.1 - 8.4e-12 44.9 21.1 0.78 10.5 0.0 10.4 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEG49252.1 - 3.7e-08 33.4 14.4 0.021 15.0 0.3 6.1 4 1 1 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEG49252.1 - 4.8e-07 29.9 22.1 0.0014 18.8 0.1 4.5 3 2 1 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 CEG49252.1 - 0.0021 17.1 1.3 0.041 12.9 0.0 2.9 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 CEG49252.1 - 0.0027 17.4 24.8 0.026 14.2 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat-like domain DUF1965 PF09248.10 CEG49252.1 - 0.04 13.7 0.4 0.86 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) BTAD PF03704.17 CEG49252.1 - 0.16 12.4 14.2 0.3 11.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TFIIA PF03153.13 CEG49252.1 - 0.33 10.9 23.7 0.64 10.0 23.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHM7_cyt PF14703.6 CEG49252.1 - 1.4 9.1 11.0 27 4.9 0.0 3.8 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter HemX PF04375.14 CEG49252.1 - 7.9 5.7 17.4 17 4.6 17.4 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_membrane PF00664.23 CEG49253.1 - 3.8e-50 171.1 30.1 3.7e-36 125.2 3.4 3.1 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG49253.1 - 3.9e-45 153.7 0.0 4e-26 92.2 0.0 3.2 3 0 0 3 3 2 2 ABC transporter Brix PF04427.18 CEG49253.1 - 7.8e-44 150.1 0.1 1.6e-43 149.1 0.1 1.5 1 0 0 1 1 1 1 Brix domain AAA_21 PF13304.6 CEG49253.1 - 1.3e-07 31.8 0.0 0.6 9.9 0.0 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEG49253.1 - 5e-07 29.8 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CEG49253.1 - 9.7e-07 28.4 0.1 0.27 10.6 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CEG49253.1 - 1e-06 28.8 0.2 0.002 18.2 0.1 3.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CEG49253.1 - 1.6e-06 28.7 7.8 0.026 15.0 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CEG49253.1 - 1.1e-05 25.7 0.7 0.26 11.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CEG49253.1 - 1.7e-05 24.5 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 CEG49253.1 - 0.00033 20.7 6.2 0.52 10.3 0.0 3.6 3 0 0 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 CEG49253.1 - 0.0015 17.9 0.2 0.25 10.7 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family cobW PF02492.19 CEG49253.1 - 0.0026 17.4 0.3 1.9 8.0 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CEG49253.1 - 0.0075 15.4 0.0 0.68 8.9 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 CEG49253.1 - 0.017 15.5 0.0 7.7 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CEG49253.1 - 0.03 13.9 0.1 12 5.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEG49253.1 - 0.057 13.8 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.6 CEG49253.1 - 0.059 13.6 0.0 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 CEG49253.1 - 0.085 11.8 0.3 0.27 10.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CEG49253.1 - 0.088 12.9 1.4 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 CEG49253.1 - 0.23 12.0 3.6 10 6.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_11 PF13086.6 CEG49253.1 - 0.4 10.4 5.2 14 5.3 4.9 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEG49253.1 - 1.1 9.4 3.9 14 5.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF2681 PF10883.8 CEG49253.1 - 2.6 8.5 8.4 13 6.3 8.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PRA1 PF03208.19 CEG49255.1 - 0.0013 18.4 5.3 0.0016 18.0 5.3 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2427 PF10348.9 CEG49255.1 - 0.016 15.0 5.0 0.055 13.3 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Trp_oprn_chp PF09534.10 CEG49255.1 - 0.018 14.8 2.9 0.022 14.5 2.9 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_A22B PF04258.13 CEG49255.1 - 0.032 13.8 2.9 0.033 13.7 2.9 1.0 1 0 0 1 1 1 0 Signal peptide peptidase DUF473 PF04322.12 CEG49255.1 - 0.041 13.7 0.2 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) TIC20 PF16166.5 CEG49255.1 - 0.044 13.6 2.1 0.056 13.2 2.1 1.1 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like LapA_dom PF06305.11 CEG49255.1 - 0.19 11.5 5.6 0.058 13.2 2.3 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NCD1 PF04904.13 CEG49256.1 - 0.072 13.1 0.3 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) FAA_hydro_N_2 PF18288.1 CEG49257.1 - 0.0045 17.4 5.1 0.096 13.1 0.1 3.9 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal domain 2 DUF3138 PF11336.8 CEG49257.1 - 0.0082 14.8 1.0 0.016 13.8 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) MHC_II_beta PF00969.19 CEG49257.1 - 0.059 13.5 0.2 2.5 8.3 0.1 3.0 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain UBD PF16455.5 CEG49257.1 - 0.06 13.6 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-binding domain Ricin_B_lectin PF00652.22 CEG49257.1 - 0.14 12.4 2.9 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Fer4_24 PF18109.1 CEG49257.1 - 0.24 11.7 2.3 0.31 11.3 0.6 2.1 2 1 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain FlxA PF14282.6 CEG49257.1 - 0.57 10.2 10.9 1.8 8.6 4.8 3.3 2 0 0 2 2 2 0 FlxA-like protein MerR-DNA-bind PF09278.11 CEG49257.1 - 0.58 10.7 6.3 1.1 9.8 1.6 2.9 2 0 0 2 2 2 0 MerR, DNA binding YjfB_motility PF14070.6 CEG49257.1 - 0.64 10.2 4.3 2 8.6 4.3 1.9 1 0 0 1 1 1 0 Putative motility protein SOGA PF11365.8 CEG49257.1 - 1.2 10.3 11.0 6.1 8.1 3.8 3.6 1 1 2 3 3 3 0 Protein SOGA CHASE6_C PF17150.4 CEG49257.1 - 1.6 9.5 4.9 16 6.3 0.0 4.2 4 1 0 4 4 4 0 C-terminal domain of two-partite extracellular sensor domain tRNA-synt_2c PF01411.19 CEG49258.1 - 1e-205 684.4 0.0 1.4e-205 684.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CEG49258.1 - 1.6e-15 56.9 0.0 5.7e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CEG49258.1 - 5.6e-10 39.8 5.0 1.8e-09 38.2 5.0 1.9 1 0 0 1 1 1 1 DHHA1 domain HK97-gp10_like PF04883.12 CEG49258.1 - 0.87 10.6 3.5 2.9 8.9 0.6 2.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component HIP1_clath_bdg PF16515.5 CEG49259.1 - 0.086 13.5 12.1 0.033 14.8 9.3 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 CEG49259.1 - 0.14 12.1 8.6 0.35 10.9 8.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CEG49259.1 - 1.4 8.7 11.8 0.37 10.6 4.7 2.3 1 1 1 2 2 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 CEG49260.1 - 0.48 11.0 17.7 2.1 9.0 17.7 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 CEG49260.1 - 0.86 7.5 4.9 1.3 6.9 4.9 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 CEG49260.1 - 1.2 8.6 8.6 1.8 8.1 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EspB PF05802.11 CEG49260.1 - 1.5 8.8 8.5 1.1 9.3 6.8 1.7 2 0 0 2 2 2 0 Enterobacterial EspB protein Cellulase PF00150.18 CEG49261.1 - 6.1e-18 65.2 0.8 8.1e-18 64.8 0.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 CEG49262.1 - 2e-38 130.0 0.0 1.4e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG49262.1 - 1.4e-05 25.1 0.0 0.00078 19.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CEG49262.1 - 0.0038 16.8 0.0 0.093 12.3 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEG49262.1 - 0.0062 16.6 0.1 0.072 13.2 0.0 2.1 2 0 0 2 2 2 1 Limkain b1 PHM7_cyt PF14703.6 CEG49262.1 - 0.014 15.6 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cas_Cas2CT1978 PF09707.10 CEG49262.1 - 0.055 13.5 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.11 CEG49262.1 - 0.36 10.6 1.4 1.2 8.9 0.5 2.2 2 1 0 2 2 2 0 Ribonuclease B OB domain DUF563 PF04577.14 CEG49263.1 - 2.7e-23 83.2 0.1 5.1e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) gag_pre-integrs PF13976.6 CEG49265.1 - 0.003 17.4 0.2 0.0061 16.4 0.2 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3741 PF12552.8 CEG49265.1 - 0.0041 17.0 0.1 0.0081 16.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3741) Tmemb_14 PF03647.13 CEG49267.1 - 4.3e-23 81.9 8.9 5.3e-23 81.6 8.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Rhomboid PF01694.22 CEG49267.1 - 0.028 14.4 5.0 0.039 13.9 5.0 1.2 1 0 0 1 1 1 0 Rhomboid family DUF2070 PF09843.9 CEG49267.1 - 0.039 12.2 0.1 0.043 12.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Rhodanese PF00581.20 CEG49270.1 - 5.3e-30 104.1 0.0 4e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SF3b10 PF07189.11 CEG49271.1 - 1e-41 140.9 0.0 1.2e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) CH PF00307.31 CEG49272.1 - 3.6e-16 59.3 0.9 6.1e-06 26.4 0.0 4.9 4 0 0 4 4 4 2 Calponin homology (CH) domain ASH PF15780.5 CEG49272.1 - 6e-12 45.6 0.0 1.6e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CAMSAP_CH PF11971.8 CEG49272.1 - 1.2e-08 34.7 1.1 0.003 17.3 0.1 3.1 3 0 0 3 3 3 2 CAMSAP CH domain IQ PF00612.27 CEG49272.1 - 0.00081 19.0 4.5 0.0017 18.0 1.7 14.2 12 1 1 13 13 13 6 IQ calmodulin-binding motif Ribosomal_60s PF00428.19 CEG49273.1 - 5e-16 59.1 3.3 6.2e-16 58.8 3.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 CEG49273.1 - 0.089 12.9 3.0 0.11 12.5 3.0 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective adh_short_C2 PF13561.6 CEG49275.1 - 3.4e-51 174.1 2.5 4.7e-51 173.6 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG49275.1 - 2.8e-43 147.7 1.6 3.6e-43 147.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG49275.1 - 1.1e-09 38.4 1.0 1.7e-09 37.8 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEG49275.1 - 0.00042 19.9 0.3 0.00089 18.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEG49275.1 - 0.00062 19.0 0.1 0.00095 18.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CEG49275.1 - 0.0021 17.5 0.1 0.0032 16.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 CEG49275.1 - 0.011 16.3 0.2 0.027 15.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 CEG49275.1 - 0.013 14.6 0.1 0.025 13.7 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 CEG49275.1 - 0.031 13.3 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 CEG49275.1 - 0.18 11.7 0.6 0.54 10.1 0.6 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OSTbeta PF15048.6 CEG49277.1 - 0.047 13.8 0.4 0.13 12.5 0.4 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein RPN6_N PF18055.1 CEG49277.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF3490 PF11995.8 CEG49277.1 - 0.17 11.7 1.3 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) DUF640 PF04852.12 CEG49278.1 - 0.19 11.9 0.1 1.6 8.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF640) WD40 PF00400.32 CEG49280.1 - 1.5e-28 98.4 3.4 1.5e-05 25.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat LisH_TPL PF17814.1 CEG49280.1 - 2.3e-15 55.9 0.4 4.8e-15 54.9 0.4 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 CEG49280.1 - 7.9e-13 48.5 0.0 4.2e-05 23.7 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG49280.1 - 5.1e-12 45.4 1.6 0.0033 16.4 0.0 4.1 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEG49280.1 - 9.8e-05 21.2 0.1 0.13 10.9 0.1 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 RHD3 PF05879.12 CEG49280.1 - 0.023 12.9 0.3 0.033 12.4 0.3 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CDtoxinA PF03498.14 CEG49280.1 - 0.059 13.0 1.1 16 5.1 0.0 3.5 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain WD40 PF00400.32 CEG49281.1 - 3e-19 69.0 5.4 0.0002 22.1 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49281.1 - 1.5e-10 41.2 1.0 3.9e-05 23.9 1.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEG49281.1 - 4.4e-09 35.5 1.4 8.9e-07 27.9 1.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ribosomal_S14 PF00253.21 CEG49284.1 - 4.7e-14 51.9 5.1 6.6e-14 51.4 5.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Pkinase PF00069.25 CEG49285.1 - 1.1e-48 165.9 0.0 2.2e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49285.1 - 6.6e-47 160.0 0.0 1.1e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CEG49285.1 - 1.8e-06 27.6 10.6 0.00025 20.8 5.9 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CEG49285.1 - 0.00067 19.5 5.6 10 6.5 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich repeat Pkinase_fungal PF17667.1 CEG49285.1 - 0.0081 15.0 0.0 0.0081 15.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase LRR_4 PF12799.7 CEG49285.1 - 0.045 14.2 13.0 0.25 11.8 1.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4381 PF14316.6 CEG49285.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FHA PF00498.26 CEG49286.1 - 4.2e-09 36.6 0.0 8.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CEG49286.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 FHA domain DUF1451 PF07295.11 CEG49287.1 - 0.63 10.1 5.9 1.2 9.2 5.7 1.5 1 1 0 1 1 1 0 Zinc-ribbon containing domain DAGK_cat PF00781.24 CEG49290.1 - 1.4e-22 79.7 0.0 5.2e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain PH PF00169.29 CEG49291.1 - 5.3e-19 68.7 0.1 6.2e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 CEG49291.1 - 4.9e-06 26.6 0.0 6.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG49291.1 - 6e-05 23.4 3.3 0.0025 18.2 3.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CEG49291.1 - 6.3e-05 23.3 0.4 0.004 17.5 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEG49291.1 - 0.00041 20.6 0.1 0.00058 20.1 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CEG49291.1 - 0.0077 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 CEG49291.1 - 0.021 15.2 0.0 0.031 14.6 0.0 1.5 1 1 0 1 1 1 0 Plant pleckstrin homology-like region Retrotrans_gag PF03732.17 CEG49292.1 - 3.7e-08 33.5 0.0 5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein ANAPC4 PF12896.7 CEG49293.1 - 0.0086 15.6 0.0 0.0089 15.5 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PhyH PF05721.13 CEG49294.1 - 5.4e-07 30.1 0.0 7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Maf_N PF08383.11 CEG49295.1 - 0.024 14.4 0.2 0.072 12.9 0.1 1.8 2 0 0 2 2 2 0 Maf N-terminal region Sec7 PF01369.20 CEG49296.1 - 1.2e-62 210.8 0.0 1e-61 207.8 0.0 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CEG49296.1 - 1.3e-29 103.1 3.3 1.3e-29 103.1 3.3 4.2 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CEG49296.1 - 4.8e-07 29.6 0.2 2e-06 27.6 0.2 2.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 HEPN_Toprim_N PF18871.1 CEG49297.1 - 3.5 7.5 6.6 0.66 9.9 0.4 2.7 2 1 1 3 3 3 0 HEPN/Toprim N-terminal domain 1 Myf5 PF12232.8 CEG49297.1 - 7.2 7.5 9.8 13 6.6 6.8 2.8 2 0 0 2 2 2 0 Myogenic determination factor 5 DHHC PF01529.20 CEG49298.1 - 0.0074 16.4 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Bromodomain PF00439.25 CEG49299.1 - 4.1e-17 62.0 0.1 7.9e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF4887 PF16228.5 CEG49299.1 - 0.013 15.7 10.1 0.013 15.7 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) U1snRNP70_N PF12220.8 CEG49299.1 - 0.16 12.6 12.7 0.94 10.2 4.6 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Med19 PF10278.9 CEG49299.1 - 0.23 11.4 38.6 13 5.7 10.0 3.2 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF1840 PF08895.11 CEG49299.1 - 0.31 11.4 6.8 0.22 11.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) RNA_polI_A34 PF08208.11 CEG49299.1 - 0.82 9.7 20.3 0.27 11.3 4.7 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Iron_permease PF04120.12 CEG49299.1 - 8.9 6.1 6.4 1.7 8.4 1.2 2.4 3 0 0 3 3 3 0 Low affinity iron permease GTP_EFTU PF00009.27 CEG49300.1 - 5.1e-66 221.9 0.0 8e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CEG49300.1 - 2.3e-27 94.9 0.0 5.5e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CEG49300.1 - 2.8e-21 75.4 0.1 6.6e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CEG49300.1 - 3.3e-11 43.0 0.0 8.6e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CEG49300.1 - 1.5e-07 31.7 0.0 6.1e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEG49300.1 - 1.8e-07 31.0 0.0 4.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CEG49300.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RINGv PF12906.7 CEG49303.1 - 2e-12 47.0 1.4 4.9e-12 45.8 1.4 1.7 1 1 0 1 1 1 1 RING-variant domain FHA PF00498.26 CEG49303.1 - 1.3e-07 31.8 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEG49303.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 CEG49303.1 - 1.6 9.2 5.5 9.9 6.6 5.9 2.1 1 1 1 2 2 2 0 Ring finger domain NAD_binding_10 PF13460.6 CEG49304.1 - 2.6e-06 27.4 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEG49304.1 - 0.0016 17.7 0.0 0.27 10.3 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 CEG49304.1 - 0.0084 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CEG49304.1 - 0.038 14.4 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyrophosphatase PF00719.19 CEG49305.1 - 9.9e-20 71.0 0.1 1.2e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Alk_phosphatase PF00245.20 CEG49312.1 - 7e-18 64.8 0.0 7.4e-12 44.9 0.0 2.0 1 1 1 2 2 2 2 Alkaline phosphatase UBX PF00789.20 CEG49313.1 - 9.2e-15 54.6 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CEG49313.1 - 1.7e-14 53.3 0.7 5.2e-14 51.8 0.7 1.9 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CEG49313.1 - 4.9e-13 49.1 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TAP_C PF03943.13 CEG49313.1 - 0.00014 21.4 0.3 0.00035 20.1 0.3 1.6 1 0 0 1 1 1 1 TAP C-terminal domain UIM PF02809.20 CEG49313.1 - 0.0019 18.0 1.5 0.0049 16.7 1.5 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif OAD_gamma PF04277.13 CEG49313.1 - 0.079 13.6 10.2 1.7 9.3 0.7 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Trypsin PF00089.26 CEG49315.1 - 1.8e-52 178.4 0.6 3.1e-52 177.6 0.6 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CEG49315.1 - 7.4e-06 26.9 0.1 2.2e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CEG49315.1 - 0.028 14.0 0.2 0.82 9.2 0.1 2.3 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 rve PF00665.26 CEG49316.1 - 1.3e-10 41.5 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DMRL_synthase PF00885.19 CEG49318.1 - 5.6e-06 26.2 0.1 9.2e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase EF-hand_7 PF13499.6 CEG49318.1 - 1.3e-05 25.6 0.3 2.7e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG49318.1 - 0.00017 21.3 0.3 0.00063 19.5 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEG49318.1 - 0.0028 17.1 1.9 0.0038 16.7 0.2 2.1 3 0 0 3 3 3 1 EF hand zf-CCHC_5 PF14787.6 CEG49319.1 - 0.032 13.9 3.3 0.19 11.4 1.4 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PX PF00787.24 CEG49322.1 - 4.6e-09 36.3 0.0 7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 PX domain PX PF00787.24 CEG49324.1 - 1e-12 48.1 0.5 1e-12 48.1 0.5 2.4 3 0 0 3 3 3 1 PX domain WH2 PF02205.20 CEG49324.1 - 6e-09 35.5 0.7 1.8e-08 33.9 0.7 1.9 1 0 0 1 1 1 1 WH2 motif COMM_domain PF07258.14 CEG49325.1 - 4e-05 23.6 2.9 0.00013 22.0 2.9 1.9 1 1 0 1 1 1 1 COMM domain TGT PF01702.18 CEG49325.1 - 0.089 11.9 0.1 0.13 11.4 0.1 1.3 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase Prominin PF05478.11 CEG49326.1 - 0.57 8.1 15.2 0.0066 14.5 7.1 1.8 2 0 0 2 2 2 0 Prominin WD40 PF00400.32 CEG49326.1 - 0.92 10.5 3.7 12 7.0 0.0 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat PH_12 PF16457.5 CEG49327.1 - 0.00083 19.9 1.1 0.0044 17.5 0.2 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 CEG49327.1 - 0.023 15.0 0.3 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain E2F_CC-MB PF16421.5 CEG49330.1 - 2.3e-30 104.8 0.0 3.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 CEG49330.1 - 4.1e-18 65.2 0.9 2.5e-17 62.7 0.1 2.4 2 1 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 CEG49330.1 - 0.0054 16.6 0.1 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF812 PF05667.11 CEG49330.1 - 0.031 13.2 0.4 0.038 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 CEG49330.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SPC25 PF06703.11 CEG49331.1 - 4.8e-28 98.0 1.2 5.9e-28 97.7 1.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Clc-like PF07062.12 CEG49331.1 - 0.016 14.7 0.2 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Clc-like HORMA PF02301.18 CEG49332.1 - 8.1e-24 84.4 0.3 1.3e-23 83.7 0.3 1.3 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CEG49332.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Bacterial HORMA domain 2 MutS_V PF00488.21 CEG49333.1 - 7e-33 114.2 0.1 9.6e-32 110.5 0.1 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEG49333.1 - 4e-24 85.9 0.2 6.2e-23 82.0 0.0 2.4 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CEG49333.1 - 3.2e-05 24.2 0.1 0.00023 21.5 0.0 2.4 3 0 0 3 3 3 1 MutS family domain IV AAA_30 PF13604.6 CEG49333.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L30 PF00327.20 CEG49333.1 - 0.092 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e SMC_N PF02463.19 CEG49333.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Syntaxin-6_N PF09177.11 CEG49333.1 - 0.35 11.5 1.5 7.7 7.1 0.1 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Peptidase_M16_M PF16187.5 CEG49336.1 - 2e-73 247.1 0.3 3.8e-73 246.2 0.1 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CEG49336.1 - 1.5e-33 115.9 0.8 4.7e-33 114.3 0.0 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEG49336.1 - 3.8e-33 115.0 0.0 1.4e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Syd PF07348.12 CEG49336.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Syd protein (SUKH-2) GMP_PDE_delta PF05351.11 CEG49337.1 - 1.5e-34 119.3 0.0 2.6e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 GMP-PDE, delta subunit Qn_am_d_aIII PF09099.10 CEG49337.1 - 0.059 13.8 0.0 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Ammonium_transp PF00909.21 CEG49338.1 - 8.4e-88 294.7 19.6 9.6e-88 294.5 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tetraspanin PF00335.20 CEG49338.1 - 1.4 8.6 6.5 11 5.6 0.3 2.9 3 0 0 3 3 3 0 Tetraspanin family Pkinase PF00069.25 CEG49339.1 - 3e-54 184.2 0.0 3.9e-53 180.5 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49339.1 - 3.5e-38 131.4 0.0 1.5e-36 126.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEG49339.1 - 2.7e-05 23.1 0.1 0.00012 21.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase zf-B_box PF00643.24 CEG49339.1 - 3.9e-05 23.7 8.7 3.9e-05 23.7 8.7 2.1 2 0 0 2 2 2 1 B-box zinc finger SAM_2 PF07647.17 CEG49339.1 - 0.0011 19.1 0.1 0.0027 17.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEG49339.1 - 0.0017 18.8 0.3 0.005 17.2 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Thioredoxin_12 PF18400.1 CEG49339.1 - 0.023 14.5 0.8 0.062 13.1 0.2 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Haspin_kinase PF12330.8 CEG49339.1 - 0.036 13.0 0.1 0.074 12.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CEG49339.1 - 0.037 13.4 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DcrB PF08786.11 CEG49339.1 - 0.039 14.0 0.0 2.5 8.2 0.0 3.1 3 0 0 3 3 3 0 DcrB zf-HIT PF04438.16 CEG49339.1 - 0.052 13.4 1.5 0.11 12.4 1.5 1.4 1 0 0 1 1 1 0 HIT zinc finger Seadorna_VP7 PF07387.11 CEG49339.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 PolC_DP2 PF03833.13 CEG49339.1 - 0.16 9.8 0.8 0.24 9.2 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-AN1 PF01428.16 CEG49339.1 - 0.71 10.1 9.6 1.9 8.7 9.6 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.21 CEG49339.1 - 0.72 10.1 6.7 2 8.7 6.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PhoD PF09423.10 CEG49340.1 - 1.4e-16 60.5 0.2 1e-15 57.6 0.2 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.28 CEG49340.1 - 0.083 13.4 1.1 0.15 12.5 1.1 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase TmoB PF06234.12 CEG49341.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) cobW PF02492.19 CEG49342.1 - 3.4e-43 147.3 0.2 5.9e-43 146.5 0.1 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEG49342.1 - 3.9e-18 65.2 0.1 9.3e-18 64.0 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CEG49342.1 - 4.6e-06 26.6 1.6 0.013 15.4 0.0 2.7 2 1 1 3 3 3 2 RsgA GTPase MeaB PF03308.16 CEG49342.1 - 0.00061 18.9 0.9 0.69 8.8 0.1 2.7 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CEG49342.1 - 0.0011 18.4 3.3 0.071 12.5 0.7 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 CEG49342.1 - 0.0043 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 CEG49342.1 - 0.01 15.2 2.2 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 CEG49342.1 - 0.04 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CEG49342.1 - 0.045 13.8 0.3 0.66 10.1 0.3 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CEG49342.1 - 0.068 13.2 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF4083 PF13314.6 CEG49342.1 - 0.11 12.5 2.7 1.2 9.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) SIT PF15330.6 CEG49342.1 - 0.17 12.4 1.5 0.31 11.5 0.5 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM52 PF14979.6 CEG49342.1 - 0.17 11.8 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane 52 AAA_23 PF13476.6 CEG49342.1 - 0.21 12.1 1.5 1.5 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Vpu PF00558.19 CEG49342.1 - 6.5 6.6 6.6 1.8 8.4 2.7 2.1 2 0 0 2 2 2 0 Vpu protein Sugar_tr PF00083.24 CEG49344.1 - 3.9e-42 144.7 19.1 5.3e-42 144.2 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG49344.1 - 4e-32 111.5 31.7 1.8e-23 83.1 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CEG49344.1 - 0.09 11.6 19.6 0.021 13.7 3.5 3.0 2 1 1 3 3 3 0 MFS_1 like family Tetraspanin PF00335.20 CEG49345.1 - 6.1e-17 62.1 13.6 1.8e-16 60.6 13.6 1.6 1 1 0 1 1 1 1 Tetraspanin family RCR PF12273.8 CEG49345.1 - 0.0055 17.3 0.8 0.013 16.2 0.8 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Thioredoxin_16 PF18569.1 CEG49345.1 - 0.066 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain PDEase_I PF00233.19 CEG49347.1 - 1.6e-67 227.7 0.3 2.6e-67 227.0 0.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MAGI_u5 PF16666.5 CEG49347.1 - 0.028 14.6 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI Minor_capsid_2 PF11114.8 CEG49347.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein MRP-S34 PF16053.5 CEG49348.1 - 8.3e-19 67.5 0.1 1.2e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Thioredoxin_6 PF13848.6 CEG49349.1 - 2.2e-08 34.2 0.1 0.00091 19.2 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 CEG49349.1 - 6.9e-06 26.0 0.6 0.92 9.5 0.0 4.8 5 1 1 6 6 6 2 Thioredoxin YL1 PF05764.13 CEG49349.1 - 0.039 14.1 16.2 0.082 13.0 16.2 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF3095 PF11294.8 CEG49349.1 - 0.098 11.7 0.3 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) Peptidase_S49_N PF08496.10 CEG49349.1 - 5 7.2 15.7 14 5.8 15.7 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PLDc_2 PF13091.6 CEG49354.1 - 2.8e-25 88.7 0.0 2e-16 60.1 0.1 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 CEG49354.1 - 1.8e-18 66.8 0.2 4.1e-17 62.4 0.0 3.0 4 0 0 4 4 4 1 PLD-like domain PLDc PF00614.22 CEG49354.1 - 2.8e-11 43.1 2.1 1.1e-06 28.5 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif MA3 PF02847.17 CEG49355.1 - 3.2e-19 69.0 1.2 1.5e-18 66.8 0.6 2.5 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CEG49355.1 - 2.4e-16 60.0 4.0 5.7e-16 58.8 0.2 2.9 2 1 0 2 2 2 1 MIF4G domain FliG_N PF14842.6 CEG49355.1 - 0.038 14.5 7.8 0.27 11.8 0.6 4.1 4 0 0 4 4 4 0 FliG N-terminal domain Spc42p PF11544.8 CEG49356.1 - 0.0024 17.8 1.1 0.012 15.5 1.1 2.2 1 0 0 1 1 1 1 Spindle pole body component Spc42p Y_phosphatase3 PF13350.6 CEG49356.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Metallophos PF00149.28 CEG49357.1 - 5e-19 69.6 2.4 8.6e-19 68.8 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 CEG49357.1 - 3.2e-17 62.9 0.7 3.2e-17 62.9 0.7 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 CEG49357.1 - 2.9e-12 47.2 0.1 1.1e-11 45.5 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.10 CEG49357.1 - 0.00034 19.7 0.5 0.063 12.3 0.4 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.7 CEG49357.1 - 0.00074 19.8 0.0 0.063 13.5 0.0 2.6 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 CEG49357.1 - 0.038 14.5 0.1 0.13 12.8 0.1 1.9 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Tape_meas_lam_C PF09718.10 CEG49359.1 - 0.085 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CLIP PF12032.8 CEG49359.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Paramecium_SA PF01508.16 CEG49360.1 - 1.2 9.6 12.6 14 6.2 2.2 2.8 1 1 2 3 3 3 0 Paramecium surface antigen domain P5-ATPase PF12409.8 CEG49362.1 - 0.041 14.0 1.0 0.052 13.6 1.0 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter DnaJ_C PF01556.18 CEG49363.1 - 1.1e-28 100.2 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEG49363.1 - 5.7e-25 87.2 2.6 6.8e-25 87.0 1.7 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEG49363.1 - 2e-14 53.7 17.0 3.2e-14 53.0 17.0 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEG49363.1 - 1e-07 31.8 7.0 0.00048 20.0 0.6 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEG49363.1 - 7.9e-05 22.7 6.1 0.089 12.8 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CEG49363.1 - 0.013 15.6 9.7 0.022 14.8 9.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 CEG49363.1 - 0.87 9.2 9.8 0.31 10.7 0.8 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 NinF PF05810.12 CEG49363.1 - 2.1 8.3 5.0 0.75 9.7 2.1 1.7 2 0 0 2 2 2 0 NinF protein Cytochrom_c3_2 PF14537.6 CEG49363.1 - 5.5 7.5 20.2 26 5.3 1.8 2.1 1 1 1 2 2 2 0 Cytochrome c3 Sugar_tr PF00083.24 CEG49364.1 - 1.4e-61 208.7 4.6 1.6e-61 208.6 4.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG49364.1 - 9.4e-15 54.4 29.8 5.4e-09 35.4 12.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tim44 PF04280.15 CEG49365.1 - 4.5e-33 114.4 0.2 4.5e-33 114.4 0.2 1.8 2 0 0 2 2 2 1 Tim44-like domain MT0933_antitox PF14013.6 CEG49365.1 - 0.087 13.1 5.1 0.41 11.0 3.2 2.5 2 0 0 2 2 2 0 MT0933-like antitoxin protein Phage_connect_1 PF05135.13 CEG49365.1 - 0.088 13.3 0.1 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein HisKA_3 PF07730.13 CEG49365.1 - 0.11 13.0 0.3 6.1 7.4 0.1 3.1 3 0 0 3 3 3 0 Histidine kinase RIBIOP_C PF04950.12 CEG49367.1 - 1e-88 297.6 0.0 1e-88 297.6 0.0 2.3 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CEG49367.1 - 8.3e-29 99.5 0.0 3.3e-28 97.6 0.0 2.2 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 CEG49367.1 - 3.1e-05 24.2 0.0 0.00021 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEG49367.1 - 0.00011 22.4 0.8 0.0027 17.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEG49367.1 - 0.00024 21.5 0.0 0.00076 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CEG49367.1 - 0.00029 20.4 0.0 0.021 14.4 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CEG49367.1 - 0.00082 19.8 0.0 0.0029 18.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG49367.1 - 0.0018 18.8 5.4 0.0045 17.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CEG49367.1 - 0.0074 16.4 0.1 0.066 13.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 CEG49367.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEG49367.1 - 0.01 16.3 3.9 0.054 14.0 0.0 3.3 3 0 0 3 3 3 0 ABC transporter PduV-EutP PF10662.9 CEG49367.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 CEG49367.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CEG49367.1 - 0.031 14.7 0.0 0.099 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase U-box PF04564.15 CEG49367.1 - 0.037 14.2 0.0 0.094 12.9 0.0 1.8 1 0 0 1 1 1 0 U-box domain AAA_30 PF13604.6 CEG49367.1 - 0.038 13.7 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEG49367.1 - 0.041 13.8 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CEG49367.1 - 0.066 12.8 0.2 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mago-bind PF09282.10 CEG49367.1 - 0.082 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Mago binding AAA_5 PF07728.14 CEG49367.1 - 0.098 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Anoctamin PF04547.12 CEG49368.1 - 1.8e-63 214.9 21.5 2.5e-63 214.5 21.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_6 PF13405.6 CEG49368.1 - 3.7e-05 23.3 1.0 0.0057 16.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CEG49368.1 - 0.00083 18.7 0.2 0.73 9.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CEG49368.1 - 0.014 15.8 0.0 0.056 13.9 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 CEG49368.1 - 0.14 12.0 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Pox_EPC_I2-L1 PF12575.8 CEG49368.1 - 0.36 11.1 2.3 26 5.1 0.0 3.4 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Cation_ATPase_C PF00689.21 CEG49368.1 - 0.48 10.1 9.4 0.17 11.6 5.5 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Glyco_hydro_17 PF00332.18 CEG49369.1 - 2.8e-05 23.9 0.2 5.2e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Pribosyltran PF00156.27 CEG49370.1 - 2.2e-14 53.2 0.2 2.9e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NRDE-2 PF08424.10 CEG49371.1 - 1.4e-40 139.4 9.2 1.2e-39 136.3 9.2 2.4 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 CEG49371.1 - 0.034 14.1 3.1 12 5.8 0.0 3.9 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 CEG49371.1 - 0.097 13.5 3.2 41 5.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 CEG49373.1 - 0.00087 19.9 0.1 0.002 18.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CEG49373.1 - 0.15 12.2 0.3 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 CEG49374.1 - 6.9e-72 242.0 0.0 9.6e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49374.1 - 6.5e-33 114.1 0.0 9.3e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CEG49374.1 - 2.4e-08 34.0 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 PX domain Pkinase_C PF00433.24 CEG49374.1 - 3.3e-07 30.9 0.3 3.3e-07 30.9 0.3 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CEG49374.1 - 0.0036 16.7 0.0 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEG49374.1 - 0.052 12.5 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF3185 PF11381.8 CEG49375.1 - 0.56 10.3 2.7 0.51 10.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) ODR4-like PF14778.6 CEG49376.1 - 2.3e-36 125.5 0.0 3.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like Ribosomal_L24e PF01246.20 CEG49378.1 - 4.6e-32 110.1 4.9 9.4e-32 109.1 4.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Protocadherin PF08374.11 CEG49378.1 - 0.093 12.7 0.1 0.093 12.7 0.1 2.6 3 0 0 3 3 3 0 Protocadherin Cu-oxidase_3 PF07732.15 CEG49379.1 - 1.9e-20 73.1 1.6 4.6e-19 68.6 0.8 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEG49379.1 - 8.6e-14 51.4 11.0 4.9e-12 45.8 2.2 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CEG49379.1 - 0.00042 20.5 0.2 0.0074 16.4 0.0 2.8 4 0 0 4 4 4 1 Multicopper oxidase VPS13_C PF16909.5 CEG49379.1 - 0.036 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Plavaka PF18759.1 CEG49382.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Plavaka transposase K1377 PF15352.6 CEG49387.1 - 0.00082 17.8 4.0 0.001 17.5 1.1 2.0 1 1 1 2 2 2 1 Susceptibility to monomelic amyotrophy End3 PF12761.7 CEG49387.1 - 0.0074 16.5 0.4 0.015 15.4 0.4 1.6 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Pro_isomerase PF00160.21 CEG49388.1 - 3.7e-42 144.3 0.0 6.5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FTP PF07504.13 CEG49388.1 - 0.058 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Ribosomal_L13 PF00572.18 CEG49389.1 - 1.1e-11 45.1 0.3 1.2e-09 38.5 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 CEG49390.1 - 6.6e-23 81.4 0.0 1.2e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49390.1 - 5.7e-11 42.2 0.0 7.8e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Aldedh PF00171.22 CEG49398.1 - 2.1e-06 26.5 0.1 2.1e-06 26.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ATG16 PF08614.11 CEG49399.1 - 0.0015 18.8 15.5 0.002 18.4 15.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cas6 PF09559.10 CEG49399.1 - 0.014 15.4 2.3 0.018 15.0 2.3 1.2 1 0 0 1 1 1 0 Cas6 Crispr TSC22 PF01166.18 CEG49399.1 - 0.033 14.5 7.5 2.3 8.6 0.3 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family ADIP PF11559.8 CEG49399.1 - 0.034 14.2 17.7 0.1 12.7 17.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 CEG49399.1 - 0.042 14.3 11.8 0.042 14.3 11.8 2.4 2 0 0 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 CEG49399.1 - 0.059 13.5 17.8 0.57 10.3 16.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 CEG49399.1 - 0.66 10.1 17.1 0.66 10.1 11.8 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 CEG49399.1 - 0.76 9.8 11.0 1 9.4 9.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 CEG49399.1 - 0.79 10.4 17.1 0.13 12.9 3.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5094 PF17015.5 CEG49399.1 - 6.4 6.9 14.5 1.7 8.7 6.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) FAM76 PF16046.5 CEG49399.1 - 9.5 5.5 11.8 12 5.1 11.8 1.1 1 0 0 1 1 1 0 FAM76 protein Stealth_CR2 PF11380.8 CEG49400.1 - 4.8e-46 155.4 0.1 2.1e-45 153.3 0.1 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CEG49400.1 - 4.4e-17 61.7 5.7 5.6e-17 61.4 1.7 2.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 CEG49400.1 - 1.7e-15 56.6 0.0 5.5e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Notch PF00066.17 CEG49400.1 - 1.5e-12 47.8 28.3 8e-07 29.4 11.8 2.5 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 CEG49400.1 - 1.3e-11 44.0 2.3 3.4e-11 42.7 2.3 1.8 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DUF21 PF01595.20 CEG49400.1 - 0.13 11.9 1.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain EF-hand_6 PF13405.6 CEG49400.1 - 0.14 12.1 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain DUF1676 PF07898.13 CEG49400.1 - 0.24 11.4 0.5 0.61 10.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) LapA_dom PF06305.11 CEG49400.1 - 0.32 10.8 1.1 29 4.6 0.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COX16 PF14138.6 CEG49401.1 - 1.3e-14 54.5 0.7 7.4e-14 52.0 0.2 2.1 2 1 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 ALMS_motif PF15309.6 CEG49402.1 - 0.00045 20.7 22.1 0.00045 20.7 22.1 6.1 5 2 1 6 6 6 1 ALMS motif Aft1_HRR PF11787.8 CEG49403.1 - 0.0026 18.9 0.2 0.0043 18.2 0.2 1.3 1 0 0 1 1 1 1 Aft1 HRR domain RXLR PF16810.5 CEG49406.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Jacalin PF01419.17 CEG49408.1 - 1.3e-07 31.6 0.2 2.4e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain AMP-binding PF00501.28 CEG49410.1 - 6.4e-90 301.8 0.0 7.6e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEG49410.1 - 7.3e-25 87.7 0.1 1.6e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEG49410.1 - 3e-18 65.5 0.2 6.5e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Rh5 PF18515.1 CEG49410.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain SIR2 PF02146.17 CEG49411.1 - 3.1e-29 102.2 0.0 5e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family PyrI_C PF02748.15 CEG49411.1 - 0.011 15.6 0.3 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Myosin_head PF00063.21 CEG49412.1 - 6e-125 418.0 1.2 8.6e-125 417.5 1.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 CEG49412.1 - 2.3e-27 95.6 0.0 9.7e-27 93.6 0.0 2.2 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.18 CEG49412.1 - 4.9e-08 33.4 0.0 1.9e-07 31.5 0.0 2.1 1 0 0 1 1 1 1 FERM central domain EF-hand_14 PF17959.1 CEG49412.1 - 0.019 15.3 0.3 0.21 11.9 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain Thioredoxin PF00085.20 CEG49413.1 - 3.4e-24 84.8 0.1 3.7e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEG49413.1 - 4.2e-05 24.0 0.1 0.00029 21.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CEG49413.1 - 0.00099 18.9 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CEG49413.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 CEG49413.1 - 0.0071 15.3 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 CEG49413.1 - 0.0077 16.1 0.1 0.0091 15.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 CEG49413.1 - 0.04 14.1 0.0 0.65 10.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin RXLR PF16810.5 CEG49414.1 - 1.2e-17 64.7 0.0 1.5e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity Thioredoxin PF00085.20 CEG49415.1 - 3.7e-15 55.8 0.0 6.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Sugar_tr PF00083.24 CEG49417.1 - 1.2e-80 271.6 27.6 1.6e-80 271.2 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG49417.1 - 6.7e-26 91.0 51.9 3.4e-21 75.6 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Auto_anti-p27 PF06677.12 CEG49418.1 - 4e-15 55.7 3.3 6.6e-15 55.0 3.3 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CxC6 PF18721.1 CEG49418.1 - 0.022 15.0 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Rep_fac-A_C PF08646.10 CEG49418.1 - 0.06 13.1 0.5 0.06 13.1 0.5 2.3 1 1 2 3 3 3 0 Replication factor-A C terminal domain Asp-B-Hydro_N PF05279.11 CEG49418.1 - 0.11 12.5 7.9 0.13 12.3 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region P5-ATPase PF12409.8 CEG49418.1 - 0.2 11.7 1.9 0.39 10.8 1.9 1.6 1 1 0 1 1 1 0 P5-type ATPase cation transporter HSP70 PF00012.20 CEG49418.1 - 0.44 8.7 8.3 0.56 8.3 8.3 1.1 1 0 0 1 1 1 0 Hsp70 protein ALMT PF11744.8 CEG49418.1 - 0.48 9.2 8.4 0.58 8.9 8.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter RNase_H2_suC PF08615.11 CEG49419.1 - 1.4e-12 48.0 0.2 7.3e-12 45.6 0.2 1.9 1 1 1 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AAA PF00004.29 CEG49421.1 - 4.8e-41 140.3 0.0 1.2e-40 139.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG49421.1 - 9.7e-13 47.7 0.1 2.3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEG49421.1 - 1.8e-10 40.6 0.0 4.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CEG49421.1 - 7.9e-07 29.6 0.0 0.00071 20.0 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CEG49421.1 - 8.8e-06 25.9 0.1 2.8e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEG49421.1 - 2.1e-05 24.5 0.3 0.00025 21.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEG49421.1 - 8e-05 22.9 0.1 0.032 14.5 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CEG49421.1 - 8.5e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 CEG49421.1 - 0.0013 18.3 0.2 0.0049 16.5 0.0 2.0 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 CEG49421.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CEG49421.1 - 0.0028 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 CEG49421.1 - 0.0028 16.8 0.0 0.0063 15.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 CEG49421.1 - 0.0046 16.3 0.3 0.11 11.8 0.0 2.8 3 0 0 3 3 3 1 KaiC Mg_chelatase PF01078.21 CEG49421.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CEG49421.1 - 0.0062 17.1 0.0 0.02 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CEG49421.1 - 0.0075 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CEG49421.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEG49421.1 - 0.015 15.0 0.1 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEG49421.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CEG49421.1 - 0.021 14.4 0.1 0.053 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 CEG49421.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CEG49421.1 - 0.033 14.0 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEG49421.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CEG49421.1 - 0.042 13.3 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2951 PF11166.8 CEG49421.1 - 0.051 13.8 0.6 0.12 12.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_14 PF13173.6 CEG49421.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEG49421.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CEG49421.1 - 0.075 12.1 0.2 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 CEG49421.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CEG49421.1 - 0.14 12.6 0.0 0.86 10.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 CEG49421.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEG49421.1 - 0.18 11.6 0.3 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AA_permease_2 PF13520.6 CEG49422.1 - 1.4e-44 152.6 44.8 1.9e-44 152.2 44.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEG49422.1 - 1.8e-38 132.3 35.6 2.3e-38 132.0 35.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 CEG49422.1 - 9.9e-18 64.0 3.6 9.9e-18 64.0 3.6 4.0 6 0 0 6 6 6 1 C-terminus of AA_permease Spore_permease PF03845.13 CEG49422.1 - 6.2e-06 25.3 21.0 2e-05 23.6 15.9 3.0 2 1 0 2 2 2 1 Spore germination protein MBOAT_2 PF13813.6 CEG49422.1 - 2.2 8.6 8.4 1 9.7 3.8 2.3 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family DEAD PF00270.29 CEG49424.1 - 1.3e-40 139.0 0.2 1.1e-39 136.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG49424.1 - 7.9e-27 93.8 0.6 9.5e-26 90.3 0.6 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG49424.1 - 1e-09 38.6 1.3 1.3e-06 28.5 0.0 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEG49424.1 - 0.015 15.6 1.3 1.5 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF809 PF05663.11 CEG49424.1 - 0.35 11.0 1.8 0.93 9.6 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Retrotran_gag_2 PF14223.6 CEG49427.1 - 1.2e-12 47.7 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Gal11_ABD1 PF18535.1 CEG49427.1 - 0.016 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) RasGEF PF00617.19 CEG49428.1 - 0.068 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 RasGEF domain P2 PF07194.11 CEG49428.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 P2 response regulator binding domain TPR_1 PF00515.28 CEG49429.1 - 0.00079 19.1 1.0 0.039 13.8 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49429.1 - 0.009 16.1 1.8 0.5 10.6 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49429.1 - 0.085 13.2 0.9 0.17 12.2 0.9 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat HMMR_C PF15908.5 CEG49430.1 - 0.12 12.7 3.2 2.2 8.5 1.3 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal RAP1 PF07218.11 CEG49431.1 - 4.8 5.3 6.3 4.9 5.3 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 CEG49435.1 - 2.3e-12 46.9 0.0 3.9e-10 39.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 CEG49435.1 - 0.0004 20.4 0.3 0.0026 17.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CEG49435.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase MeaB PF03308.16 CEG49437.1 - 0.0046 16.0 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Pkinase PF00069.25 CEG49439.1 - 2.2e-49 168.2 0.0 3.1e-21 75.9 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49439.1 - 1.4e-25 90.1 0.0 1.5e-12 47.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CEG49439.1 - 2.8e-14 53.4 0.0 7.2e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CEG49439.1 - 3.7e-07 29.7 0.0 0.01 15.1 0.0 2.7 1 1 1 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 CEG49439.1 - 5.2e-06 26.2 0.1 5.2e-06 26.2 0.1 2.6 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs FTA2 PF13095.6 CEG49439.1 - 0.0039 16.8 4.2 0.2 11.3 0.0 3.3 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CEG49439.1 - 0.0068 15.7 0.0 0.037 13.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEG49439.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cbl_N PF02262.16 CEG49439.1 - 0.16 12.0 2.1 0.47 10.5 2.1 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Prenyltrans PF00432.21 CEG49441.1 - 2e-56 187.3 13.3 2e-13 49.8 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CEG49441.1 - 3.7e-05 23.0 0.0 1.3 8.1 0.0 3.4 2 2 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CEG49441.1 - 0.0047 16.1 0.0 0.098 11.7 0.0 2.5 2 1 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain Proteasome PF00227.26 CEG49442.1 - 2.9e-50 170.4 0.7 3.5e-50 170.1 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CEG49442.1 - 0.24 10.8 0.0 0.24 10.8 0.0 2.5 3 0 0 3 3 3 0 Proteasome beta subunits C terminal Ribosomal_S13 PF00416.22 CEG49443.1 - 1.2e-51 174.4 1.6 1.4e-51 174.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEG49443.1 - 0.048 12.4 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4524 PF15025.6 CEG49444.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) ARL2_Bind_BART PF11527.8 CEG49444.1 - 0.04 14.0 6.5 0.12 12.5 2.6 2.3 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART SurA_N_3 PF13624.6 CEG49444.1 - 0.067 13.0 7.3 0.39 10.5 0.5 2.6 2 0 0 2 2 2 0 SurA N-terminal domain DUF1910 PF08928.10 CEG49444.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) MHB PF16525.5 CEG49444.1 - 0.27 11.5 2.2 4.6 7.6 1.7 2.6 2 0 0 2 2 2 0 Haemophore, haem-binding DUF4296 PF14129.6 CEG49444.1 - 0.81 10.3 6.2 0.94 10.1 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) TipAS PF07739.13 CEG49444.1 - 0.9 10.1 11.8 0.16 12.5 5.8 2.3 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF737 PF05300.11 CEG49444.1 - 2.4 8.5 8.7 1.7 9.0 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF737) SPARC_Ca_bdg PF10591.9 CEG49444.1 - 3.3 8.1 5.1 0.59 10.5 0.8 1.9 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GrpE PF01025.19 CEG49444.1 - 5 6.8 9.7 20 4.8 5.0 3.0 1 1 2 3 3 3 0 GrpE ArdA PF07275.11 CEG49444.1 - 5.5 7.5 9.2 1.3 9.5 3.5 2.3 1 1 0 2 2 2 0 Antirestriction protein (ArdA) ALC PF17527.2 CEG49445.1 - 0.19 11.4 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Phage ALC protein Na_H_Exchanger PF00999.21 CEG49446.1 - 4.4e-47 160.7 35.2 6.4e-47 160.2 35.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SURF1 PF02104.15 CEG49446.1 - 3.7e-32 112.0 0.0 7.7e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 SURF1 family LRR19-TM PF15176.6 CEG49446.1 - 0.52 10.3 3.7 33 4.5 2.8 3.5 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF4064 PF13273.6 CEG49446.1 - 1.6 9.0 17.5 0.92 9.8 0.4 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) Bin3 PF06859.12 CEG49447.1 - 1.5e-19 70.6 0.4 3.4e-19 69.5 0.1 1.7 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 CEG49447.1 - 7.4e-12 45.3 0.1 2.1e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain dsrm PF00035.26 CEG49447.1 - 3.8e-10 40.3 0.0 7.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Methyltransf_25 PF13649.6 CEG49447.1 - 4.7e-06 27.2 0.2 0.19 12.5 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEG49447.1 - 0.001 18.9 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 CEG49447.1 - 0.017 14.7 0.9 0.17 11.4 0.1 2.3 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 CEG49447.1 - 0.019 15.7 0.1 8.1 7.3 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain RNA_pol_L PF01193.24 CEG49447.1 - 0.029 13.8 0.0 0.043 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ubie_methyltran PF01209.18 CEG49447.1 - 0.058 12.7 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CEG49451.1 - 9.5e-07 28.4 0.1 1.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase ERCC4 PF02732.15 CEG49453.1 - 5.9e-20 72.0 0.6 1e-19 71.2 0.6 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 CEG49453.1 - 7.5e-08 32.6 0.1 1.9e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Flt3_lig PF02947.14 CEG49453.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 flt3 ligand Pkinase PF00069.25 CEG49454.1 - 1e-51 175.8 0.2 3e-46 157.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49454.1 - 7e-28 97.6 0.1 1.2e-24 87.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEG49454.1 - 3.4e-05 23.3 0.0 6.3e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEG49454.1 - 0.0036 16.7 0.1 0.0089 15.4 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEG49454.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CEG49454.1 - 0.057 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PUB_1 PF18486.1 CEG49454.1 - 0.14 12.1 0.1 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Ndc1_Nup PF09531.10 CEG49454.1 - 0.71 8.5 5.1 0.92 8.1 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FliJ PF02050.16 CEG49455.1 - 0.12 12.6 12.6 0.55 10.5 5.1 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein LSM PF01423.22 CEG49456.1 - 5.3e-18 64.5 0.3 6.5e-18 64.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain HECT PF00632.25 CEG49458.1 - 1e-64 219.0 0.0 8e-64 216.0 0.0 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Mo25 PF08569.11 CEG49458.1 - 0.057 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Mo25-like Arm PF00514.23 CEG49458.1 - 2.6 8.2 6.9 31 4.8 0.2 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PMG PF05287.12 CEG49461.1 - 0.071 13.1 4.2 0.12 12.5 4.2 1.3 1 0 0 1 1 1 0 PMG protein ABC_membrane_2 PF06472.15 CEG49463.1 - 4.5e-83 278.8 7.2 6.6e-83 278.2 7.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEG49463.1 - 5e-17 62.7 0.0 1.4e-16 61.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CEG49463.1 - 0.00022 20.7 0.2 0.19 11.2 0.2 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEG49463.1 - 0.002 18.0 0.1 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 CEG49463.1 - 0.0057 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_23 PF13476.6 CEG49463.1 - 0.016 15.7 0.0 0.049 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain GIY-YIG PF01541.24 CEG49464.1 - 4.5e-13 49.3 0.0 2.9e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 CEG49464.1 - 4e-05 23.7 7.8 4e-05 23.7 7.8 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 CEG49464.1 - 0.073 13.4 11.0 0.19 12.1 11.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 CEG49464.1 - 0.14 12.4 9.8 0.31 11.3 9.8 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 CEG49464.1 - 0.78 9.7 13.1 0.81 9.7 8.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 CEG49464.1 - 0.82 9.6 11.5 2.7 7.9 8.7 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEG49464.1 - 1.2 9.6 12.6 6.7 7.1 8.2 2.5 2 0 0 2 2 2 0 C1 domain YdjO PF14169.6 CEG49464.1 - 1.5 8.6 7.1 1.4 8.7 0.2 2.8 1 1 2 3 3 3 0 Cold-inducible protein YdjO Kazal_1 PF00050.21 CEG49465.1 - 8.3e-37 125.0 39.2 3.5e-10 39.7 4.2 4.7 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CEG49465.1 - 6.7e-31 106.2 51.7 3.6e-09 36.6 3.7 4.9 5 0 0 5 5 5 4 Kazal-type serine protease inhibitor domain PDZ_6 PF17820.1 CEG49466.1 - 6.3e-09 35.6 0.9 1.1e-08 34.8 0.9 1.4 1 0 0 1 1 1 1 PDZ domain Nas2_N PF18265.1 CEG49466.1 - 1.3e-08 34.6 0.4 1.3e-08 34.6 0.4 3.2 3 1 1 4 4 4 1 Nas2 N_terminal domain PDZ_2 PF13180.6 CEG49466.1 - 3.4e-06 27.3 0.2 5.7e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEG49466.1 - 4e-06 27.1 0.2 8.6e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 CEG49466.1 - 8.3e-05 22.9 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Sigma54_CBD PF04963.13 CEG49466.1 - 0.022 14.6 1.1 0.045 13.6 1.1 1.5 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF3253 PF11625.8 CEG49466.1 - 0.08 13.2 0.3 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Ribosomal_S11 PF00411.19 CEG49467.1 - 9.6e-47 157.9 1.8 1.2e-46 157.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 CEG49467.1 - 0.036 13.1 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) CBM_25 PF03423.13 CEG49467.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Prp19 PF08606.11 CEG49468.1 - 1e-33 115.1 2.2 1.9e-33 114.2 2.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CEG49468.1 - 1.2e-31 108.2 8.6 7.2e-08 33.0 0.0 7.8 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49468.1 - 1.6e-12 47.6 0.1 0.00082 19.6 0.0 5.9 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 CEG49468.1 - 2.3e-06 27.3 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ge1_WD40 PF16529.5 CEG49468.1 - 0.0024 16.9 0.5 0.53 9.2 0.0 3.6 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3450 PF11932.8 CEG49468.1 - 0.024 14.0 1.1 0.039 13.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) U-box PF04564.15 CEG49468.1 - 0.03 14.5 0.0 0.096 12.9 0.0 1.9 1 0 0 1 1 1 0 U-box domain WD40_like PF17005.5 CEG49468.1 - 0.048 13.0 0.0 0.38 10.0 0.0 2.3 1 1 1 3 3 3 0 WD40-like domain SlyX PF04102.12 CEG49468.1 - 0.065 13.9 1.1 0.19 12.4 1.1 1.7 1 0 0 1 1 1 0 SlyX Rtf2 PF04641.12 CEG49468.1 - 0.2 11.0 2.4 4.2 6.7 0.0 2.6 1 1 1 2 2 2 0 Rtf2 RING-finger FUSC PF04632.12 CEG49468.1 - 0.67 8.4 4.1 0.95 7.9 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 CEG49468.1 - 1.7 9.1 4.6 1.4 9.3 2.7 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TPH PF13868.6 CEG49469.1 - 1.9e-45 154.9 133.5 1.9e-45 154.9 133.5 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Glu-tRNAGln PF02686.15 CEG49471.1 - 0.064 13.6 0.3 0.41 11.0 0.2 2.4 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Cnn_1N PF07989.11 CEG49472.1 - 1.1e-10 41.5 7.4 1.1e-10 41.5 7.4 12.0 6 3 3 9 9 9 2 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CEG49472.1 - 0.0053 16.8 19.4 0.0053 16.8 19.4 9.3 1 1 9 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YnfE PF17452.2 CEG49472.1 - 0.018 15.3 1.9 0.018 15.3 1.9 5.1 4 1 1 5 5 5 0 Uncharacterized YnfE-like CAP PF00188.26 CEG49473.1 - 2.8e-09 37.9 1.2 4.5e-09 37.2 1.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MitMem_reg PF13012.6 CEG49474.1 - 2.3e-33 115.0 0.4 3.8e-33 114.3 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEG49474.1 - 5.4e-26 90.9 0.0 1.3e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF525 PF04379.14 CEG49475.1 - 3.4e-18 65.7 0.0 5.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 ApaG domain Lipoprotein_3 PF00938.17 CEG49475.1 - 0.007 16.5 0.3 0.28 11.4 0.1 2.2 2 0 0 2 2 2 1 Lipoprotein Tox-HNH-EHHH PF15657.6 CEG49475.1 - 0.026 14.9 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Complex1_LYR PF05347.15 CEG49475.1 - 0.065 13.3 4.0 0.3 11.1 0.3 2.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Malic_M PF03949.15 CEG49476.1 - 1.1e-81 273.9 1.6 2.2e-56 191.0 0.1 2.2 1 1 1 2 2 2 2 Malic enzyme, NAD binding domain malic PF00390.19 CEG49476.1 - 1.3e-72 243.4 0.0 4.7e-72 241.6 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 CEG49476.1 - 0.048 13.7 0.3 1.1 9.3 0.3 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CEG49476.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_2 PF13923.6 CEG49478.1 - 1.8e-12 46.9 7.8 3.1e-12 46.1 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG49478.1 - 1.4e-09 38.1 7.4 2.5e-09 37.3 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEG49478.1 - 1.1e-08 34.8 7.7 1.9e-08 34.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG49478.1 - 1.6e-07 31.1 7.8 3e-07 30.2 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEG49478.1 - 5.5e-07 29.4 7.6 9.9e-07 28.6 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEG49478.1 - 2.2e-06 27.6 6.9 4.6e-06 26.6 6.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEG49478.1 - 4.2e-06 26.5 11.0 6.3e-06 26.0 8.5 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG49478.1 - 4.5e-06 26.7 7.3 8.4e-06 25.9 7.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CEG49478.1 - 2e-05 24.4 3.3 3.6e-05 23.5 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEG49478.1 - 0.00055 20.2 6.3 0.0016 18.6 6.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CEG49478.1 - 0.0047 16.7 4.8 0.011 15.5 4.8 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 CEG49478.1 - 0.007 16.2 3.2 0.014 15.2 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CEG49478.1 - 0.019 15.1 6.1 0.033 14.3 6.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 CEG49478.1 - 0.044 13.6 0.1 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 CEG49478.1 - 0.16 11.8 5.4 0.37 10.6 5.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger LRV_FeS PF05484.11 CEG49478.1 - 0.62 10.1 4.0 1.3 9.1 4.0 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster GCP_C_terminal PF04130.13 CEG49479.1 - 2.1e-22 80.0 9.3 6.1e-22 78.5 9.3 1.8 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEG49479.1 - 2.1e-10 40.7 0.1 4.5e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Pkinase PF00069.25 CEG49480.1 - 6.2e-67 225.7 0.1 1.2e-66 224.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49480.1 - 2.7e-40 138.3 0.0 3.8e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 CEG49480.1 - 8.9e-12 45.0 0.0 2.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CEG49480.1 - 3.9e-09 36.2 0.0 1.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEG49480.1 - 0.0014 18.6 0.0 0.01 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sushi_2 PF09014.10 CEG49480.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Beta-2-glycoprotein-1 fifth domain FTA2 PF13095.6 CEG49480.1 - 0.016 14.9 0.4 2.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEG49480.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Not1 PF04054.15 CEG49481.1 - 2.1e-132 441.5 0.1 5.7e-132 440.1 0.1 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CEG49481.1 - 2.4e-90 301.8 5.6 4.8e-89 297.6 1.0 2.4 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CEG49481.1 - 4.8e-56 188.9 0.6 1.1e-55 187.7 0.6 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CEG49481.1 - 6e-56 188.5 0.7 6e-56 188.5 0.7 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CEG49481.1 - 2.4e-22 79.6 0.0 5.7e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat C2 PF00168.30 CEG49485.1 - 2.7e-09 37.2 0.0 5.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain YjhX_toxin PF09857.9 CEG49485.1 - 0.031 14.2 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair Ank_2 PF12796.7 CEG49486.1 - 4.7e-33 113.6 0.1 1.6e-10 41.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG49486.1 - 5.8e-30 103.3 0.7 9.5e-13 48.4 0.0 5.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG49486.1 - 6.7e-22 77.3 3.3 2.7e-06 27.5 0.1 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CEG49486.1 - 4e-21 74.5 1.9 3.5e-06 27.2 0.1 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 CEG49486.1 - 4e-21 72.8 0.7 0.00012 22.2 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Fic PF02661.18 CEG49486.1 - 2e-12 47.9 0.0 9.3e-12 45.7 0.0 2.3 1 0 0 1 1 1 1 Fic/DOC family bHLH-MYC_N PF14215.6 CEG49486.1 - 5.4e-05 23.6 0.0 0.00016 22.0 0.0 1.8 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal DUF3978 PF13123.6 CEG49486.1 - 0.0016 18.2 0.1 0.0078 16.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3978) DUF4796 PF16044.5 CEG49486.1 - 0.032 13.8 0.0 0.83 9.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4796) TFCD_C PF12612.8 CEG49486.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal RRP7 PF12923.7 CEG49487.1 - 2.5e-26 92.2 15.7 2.5e-26 92.2 15.7 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 CEG49487.1 - 7.6e-05 22.6 0.1 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain AAA_30 PF13604.6 CEG49487.1 - 0.1 12.3 0.6 0.15 11.7 0.6 1.4 1 1 0 1 1 1 0 AAA domain DUF1779 PF08680.10 CEG49487.1 - 0.31 11.2 5.4 0.59 10.3 5.4 1.4 1 0 0 1 1 1 0 TATA-box binding NAD_Gly3P_dh_C PF07479.14 CEG49494.1 - 2.9e-49 167.0 0.1 6e-49 166.0 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CEG49494.1 - 4.1e-47 160.1 0.0 1.1e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 CEG49494.1 - 0.0011 19.5 0.1 0.014 16.0 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CEG49494.1 - 0.01 16.3 0.0 0.03 14.8 0.0 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PDH PF02153.17 CEG49494.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase 2OG-FeII_Oxy_3 PF13640.6 CEG49495.1 - 4.9e-19 69.0 0.0 8.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CEG49495.1 - 4.7e-09 36.8 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 CEG49495.1 - 0.045 14.0 0.0 0.068 13.4 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) FAD-oxidase_C PF02913.19 CEG49496.1 - 3.5e-44 151.3 0.0 5e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEG49496.1 - 1.8e-20 73.1 0.1 5.3e-15 55.4 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain Phenyl_P_gamma PF09662.10 CEG49496.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) KOG2701 PF09762.9 CEG49497.1 - 2.9e-38 131.9 0.1 2.9e-38 131.9 0.1 3.3 4 0 0 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) Phage_T4_Ndd PF06591.11 CEG49497.1 - 0.019 14.7 0.2 0.35 10.6 0.0 2.6 3 0 0 3 3 3 0 T4-like phage nuclear disruption protein (Ndd) CAMSAP_CKK PF08683.11 CEG49498.1 - 9.5e-22 77.4 0.0 2.2e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated DUF2833 PF11090.8 CEG49501.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DWNN PF08783.11 CEG49501.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 DWNN domain C2-C2_1 PF11618.8 CEG49502.1 - 1.7e-34 118.9 0.0 2.7e-31 108.6 0.0 2.9 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 EF-hand_6 PF13405.6 CEG49502.1 - 7.2e-11 41.1 1.6 0.023 14.6 0.0 7.1 6 0 0 6 6 6 3 EF-hand domain C2 PF00168.30 CEG49502.1 - 6.7e-08 32.8 0.0 1.9e-05 24.9 0.0 3.1 2 0 0 2 2 2 1 C2 domain EF-hand_8 PF13833.6 CEG49502.1 - 3.2e-07 30.1 0.2 0.033 14.0 0.0 5.7 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_7 PF13499.6 CEG49502.1 - 3.6e-06 27.3 8.1 11 6.5 0.0 8.3 10 0 0 10 10 10 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG49502.1 - 1.4e-05 24.3 0.0 23 4.8 0.0 6.4 7 0 0 7 7 7 0 EF hand EF-hand_9 PF14658.6 CEG49502.1 - 0.00013 22.2 0.2 69 3.9 0.0 7.1 8 0 0 8 8 8 0 EF-hand domain Cytokin_check_N PF10407.9 CEG49502.1 - 0.027 14.4 1.1 4.2 7.4 0.8 3.2 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus HEPN_Toprim_N PF18871.1 CEG49502.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.9 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 Tudor_4 PF18358.1 CEG49503.1 - 9e-10 38.0 7.3 0.00015 21.3 1.2 2.8 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain MBT PF02820.18 CEG49503.1 - 4.8e-06 26.8 1.4 0.044 14.1 0.1 3.1 3 0 0 3 3 3 2 mbt repeat SAWADEE PF16719.5 CEG49503.1 - 0.00012 22.1 3.9 0.033 14.2 0.5 3.0 2 0 0 2 2 2 2 SAWADEE domain Tudor-knot PF11717.8 CEG49503.1 - 0.0056 16.5 15.3 0.093 12.6 2.8 3.9 4 0 0 4 4 4 2 RNA binding activity-knot of a chromodomain DOR PF14839.6 CEG49503.1 - 1.7 8.5 8.7 7.5 6.4 2.8 2.4 2 0 0 2 2 2 0 DOR family GST_N_2 PF13409.6 CEG49504.1 - 4.8e-12 46.0 0.1 5.9e-11 42.5 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEG49504.1 - 7.1e-11 42.4 0.0 3.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEG49504.1 - 1.8e-07 31.4 0.1 4.4e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain AAA_33 PF13671.6 CEG49505.1 - 2.5e-18 66.6 0.0 5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG49505.1 - 2.6e-09 36.6 0.0 7.9e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CEG49505.1 - 3.9e-07 30.7 0.1 1e-06 29.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEG49505.1 - 4.3e-06 26.4 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 CEG49505.1 - 4.9e-06 26.5 0.2 9.6e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 CEG49505.1 - 2.2e-05 24.9 0.1 4.7e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 CEG49505.1 - 0.00052 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 CEG49505.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1967 PF09269.11 CEG49505.1 - 0.094 12.7 0.8 0.35 10.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) AAA_16 PF13191.6 CEG49505.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain CUB_2 PF02408.20 CEG49506.1 - 0.084 12.6 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 CUB-like domain zf-RING_2 PF13639.6 CEG49507.1 - 2.8e-11 43.6 10.8 5.5e-11 42.6 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG49507.1 - 2.4e-10 40.5 6.5 5.8e-10 39.3 6.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEG49507.1 - 4.9e-08 32.7 5.9 8.9e-08 31.9 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG49507.1 - 6.1e-08 32.4 10.7 1.4e-07 31.2 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG49507.1 - 2.6e-07 30.4 9.4 5.3e-07 29.4 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG49507.1 - 4.3e-06 26.4 7.6 1.3e-05 24.9 7.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEG49507.1 - 4.6e-06 26.6 6.1 4.6e-06 26.6 6.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG49507.1 - 0.00011 22.0 8.5 0.0002 21.3 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEG49507.1 - 0.00057 19.9 5.8 0.0014 18.6 5.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEG49507.1 - 0.004 17.0 9.5 0.009 15.9 9.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 CEG49507.1 - 0.03 14.5 5.3 0.073 13.2 5.3 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CEG49507.1 - 0.089 12.4 6.8 0.18 11.5 6.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CEG49507.1 - 0.093 12.9 10.2 0.38 11.0 10.2 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CEG49507.1 - 0.43 10.8 7.2 2.1 8.6 7.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Tmpp129 PF10272.9 CEG49507.1 - 0.62 9.3 5.9 0.3 10.3 1.7 2.0 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-RING-like PF08746.11 CEG49507.1 - 3.9 7.9 7.8 9.8 6.6 7.8 1.7 1 1 0 1 1 1 0 RING-like domain Hydrolase_6 PF13344.6 CEG49512.1 - 3.8e-29 100.8 0.0 5.9e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEG49512.1 - 1.3e-19 70.0 0.0 2.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEG49512.1 - 9.9e-10 39.0 0.0 1.3e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEG49512.1 - 9e-05 22.6 0.0 0.0021 18.2 0.0 2.4 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CEG49512.1 - 0.079 12.6 0.1 0.35 10.5 0.0 2.0 2 1 1 3 3 3 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 CEG49512.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) S-AdoMet_synt_M PF02772.16 CEG49513.1 - 1.4 9.2 4.8 3 8.1 2.8 2.6 1 1 1 2 2 2 0 S-adenosylmethionine synthetase, central domain WD40 PF00400.32 CEG49514.1 - 6.4e-14 52.1 16.1 0.0014 19.5 0.1 7.1 6 2 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49514.1 - 1e-10 41.8 0.7 0.0086 16.3 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG49514.1 - 1e-07 32.1 2.7 0.0006 19.7 0.4 4.2 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CEG49514.1 - 0.00066 19.5 0.0 0.22 11.5 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 CEG49514.1 - 0.02 13.7 0.4 0.8 8.4 0.0 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region POLO_box PF00659.18 CEG49514.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.5 4 0 0 4 4 4 0 POLO box duplicated region SET PF00856.28 CEG49515.1 - 2e-09 38.1 0.0 5e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 SET domain DDE_1 PF03184.19 CEG49516.1 - 2.9e-12 46.6 0.0 5.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 CEG49516.1 - 0.00057 19.5 0.4 0.0012 18.5 0.4 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 CEG49516.1 - 0.0035 17.3 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain UPF0257 PF06788.13 CEG49516.1 - 0.043 13.6 0.1 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0257) HTH_3 PF01381.22 CEG49516.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Josephin PF02099.17 CEG49516.1 - 0.12 12.4 0.0 0.76 9.9 0.0 2.2 2 1 0 2 2 2 0 Josephin HTH_38 PF13936.6 CEG49516.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DEAD PF00270.29 CEG49519.1 - 9.5e-45 152.5 0.2 4.3e-44 150.4 0.1 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG49519.1 - 7.5e-27 93.9 0.3 5.9e-26 91.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEG49519.1 - 4.2e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEG49519.1 - 0.0027 17.1 0.0 0.0088 15.4 0.0 1.8 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.14 CEG49519.1 - 0.044 13.1 0.2 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain tRNA-synt_2b PF00587.25 CEG49520.1 - 4e-17 62.8 0.2 9.7e-17 61.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEG49520.1 - 4.3e-12 46.2 5.5 6.7e-12 45.6 5.5 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1043 PF06295.12 CEG49520.1 - 0.0041 17.1 0.8 0.0095 15.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) DUF4618 PF15397.6 CEG49520.1 - 0.071 12.5 6.0 0.11 11.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Macoilin PF09726.9 CEG49520.1 - 0.11 11.0 4.4 0.16 10.5 4.4 1.1 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 CEG49520.1 - 0.35 8.8 4.8 0.48 8.3 4.8 1.1 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.9 CEG49520.1 - 0.4 10.7 7.5 1.6 8.8 1.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 CEG49520.1 - 0.48 9.9 4.3 0.72 9.4 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 CEG49520.1 - 0.53 10.4 7.9 0.6 10.2 6.2 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 CEG49520.1 - 0.61 10.1 11.0 2.5 8.1 11.0 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5082 PF16888.5 CEG49520.1 - 0.75 10.1 7.9 7.9 6.8 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 CEG49520.1 - 2.8 8.3 5.9 12 6.3 4.3 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sds3 PF08598.11 CEG49521.1 - 1.2e-05 25.4 12.5 1.2e-05 25.4 12.5 1.7 1 1 0 1 1 1 1 Sds3-like HOCHOB PF17943.1 CEG49521.1 - 0.24 12.1 5.8 0.29 11.8 0.3 2.7 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox ACPS PF01648.20 CEG49523.1 - 4.4e-18 65.5 0.0 1.3e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily vATP-synt_E PF01991.18 CEG49524.1 - 6.6e-45 153.0 13.9 7.8e-45 152.7 13.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4448 PF14610.6 CEG49526.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PMP1_2 PF08114.11 CEG49526.1 - 0.023 14.4 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Phos_pyr_kin PF08543.12 CEG49527.1 - 5.3e-16 58.8 0.0 1.5e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CEG49527.1 - 1e-08 34.9 0.0 1.1e-06 28.2 0.0 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase DUF370 PF04025.12 CEG49527.1 - 0.13 12.4 0.4 0.32 11.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF370) PCI PF01399.27 CEG49528.1 - 1.5e-19 70.5 0.3 6.3e-19 68.4 0.3 2.1 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CEG49528.1 - 3.8e-05 23.7 0.0 0.0001 22.3 0.0 1.8 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 CEG49528.1 - 0.013 15.8 1.3 4.4 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49528.1 - 0.014 15.4 4.2 7.9 6.8 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49528.1 - 0.046 14.6 0.8 55 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat KH_8 PF17903.1 CEG49528.1 - 0.079 13.1 0.1 0.35 11.0 0.0 2.1 1 1 1 2 2 2 0 Krr1 KH1 domain RPN7 PF10602.9 CEG49528.1 - 0.8 9.4 5.6 3.9 7.1 0.1 3.4 3 1 1 4 4 4 0 26S proteasome subunit RPN7 Got1 PF04178.12 CEG49529.1 - 4.2e-29 101.2 15.1 5.7e-29 100.8 15.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family PH PF00169.29 CEG49530.1 - 4.3e-08 33.6 0.7 1.4e-07 31.9 0.2 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 CEG49530.1 - 0.034 14.4 0.1 0.077 13.3 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Elf-1_N PF12310.8 CEG49530.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor protein N terminal Beta-lactamase2 PF13354.6 CEG49531.1 - 4.9e-08 32.8 0.0 6.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 CEG49531.1 - 2.1e-06 27.2 0.0 2.4e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase RICTOR_V PF14668.6 CEG49535.1 - 0.13 12.5 0.7 0.51 10.6 0.2 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Exonuc_VII_L PF02601.15 CEG49538.1 - 0.022 14.3 7.4 0.025 14.1 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 CEG49538.1 - 0.038 12.6 0.5 0.043 12.4 0.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1640 PF07798.11 CEG49538.1 - 0.1 12.6 12.4 0.14 12.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Vicilin_N PF04702.12 CEG49538.1 - 0.14 12.0 19.1 0.19 11.6 19.1 1.2 1 0 0 1 1 1 0 Vicilin N terminal region PRY PF13765.6 CEG49538.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 SPRY-associated domain AAA_11 PF13086.6 CEG49538.1 - 0.49 10.1 6.0 0.59 9.9 6.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEG49538.1 - 0.58 10.6 4.3 0.75 10.3 4.3 1.1 1 0 0 1 1 1 0 AAA domain Ino80_Iec3 PF14612.6 CEG49538.1 - 0.74 10.4 12.9 0.11 13.2 5.6 2.1 1 1 1 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling LMBR1 PF04791.16 CEG49538.1 - 0.83 8.5 5.6 0.92 8.3 5.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Asp-B-Hydro_N PF05279.11 CEG49538.1 - 1.5 8.8 7.9 2 8.5 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FadA PF09403.10 CEG49538.1 - 4 8.0 11.1 5.3 7.6 3.9 2.3 1 1 1 2 2 2 0 Adhesion protein FadA OrfB_IS605 PF01385.19 CEG49538.1 - 4.4 7.6 16.3 7.7 6.8 8.9 2.1 1 1 1 2 2 2 0 Probable transposase Peptidase_M24 PF00557.24 CEG49539.1 - 1.4e-38 132.7 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CEG49539.1 - 3.8e-38 131.1 0.1 1.3e-37 129.4 0.1 1.9 1 1 1 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CEG49539.1 - 6e-22 77.5 0.3 1.3e-21 76.4 0.3 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CEG49539.1 - 9.7e-22 78.0 0.0 1.4e-14 54.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CE2_N PF17996.1 CEG49540.1 - 3.4e-12 46.3 0.0 9.5e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 CEG49540.1 - 7.6e-12 46.0 0.0 1.2e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEG49540.1 - 0.0039 17.2 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_2 PF07719.17 CEG49541.1 - 6.3e-11 41.5 15.6 0.012 15.7 0.1 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEG49541.1 - 7.3e-10 38.2 14.5 0.025 14.4 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEG49541.1 - 3.7e-09 36.1 1.4 0.12 12.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat cNMP_binding PF00027.29 CEG49541.1 - 6.9e-09 35.7 0.0 0.023 14.7 0.0 3.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain TPR_17 PF13431.6 CEG49541.1 - 0.00066 19.9 2.6 2.3 8.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49541.1 - 0.0015 18.1 0.5 0.022 14.5 0.1 2.7 2 1 1 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 CEG49541.1 - 0.0021 18.1 0.7 0.012 15.6 0.1 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CEG49541.1 - 0.0031 17.6 3.8 0.27 11.4 0.5 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49541.1 - 0.0042 17.7 6.8 0.078 13.6 0.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49541.1 - 0.016 15.4 14.5 0.25 11.6 3.3 3.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49541.1 - 0.028 15.2 5.7 0.22 12.4 0.1 4.4 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEG49541.1 - 0.033 14.7 2.8 0.83 10.2 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49541.1 - 0.041 13.9 7.7 6.6 7.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49541.1 - 0.042 14.5 4.1 2 9.2 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat C5HCH PF17982.1 CEG49541.1 - 0.086 13.0 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 NSD Cys-His rich domain Coatomer_E PF04733.14 CEG49541.1 - 0.2 11.1 0.3 1.9 7.9 0.1 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit JIP_LZII PF16471.5 CEG49542.1 - 0.12 12.5 0.2 0.12 12.5 0.2 6.1 6 1 1 7 7 7 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 CEG49542.1 - 0.26 11.4 0.1 0.26 11.4 0.1 6.7 7 1 0 7 7 7 0 bZIP transcription factor DivIC PF04977.15 CEG49542.1 - 6 6.7 32.6 0.29 11.0 0.8 6.8 4 2 3 7 7 7 0 Septum formation initiator PX PF00787.24 CEG49543.1 - 0.022 14.7 0.1 0.063 13.3 0.1 1.7 1 1 0 1 1 1 0 PX domain ATP_transf PF09830.9 CEG49544.1 - 1.2e-15 57.4 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase RNase_T PF00929.24 CEG49545.1 - 3.9e-09 37.2 0.0 7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease NCBP3 PF10309.9 CEG49545.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Kinesin PF00225.23 CEG49546.1 - 6e-103 344.3 3.5 1.4e-102 343.1 3.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG49546.1 - 3.6e-22 78.9 0.4 3.6e-22 78.9 0.4 2.5 2 1 0 2 2 2 1 Microtubule binding bZIP_1 PF00170.21 CEG49546.1 - 0.0019 18.2 6.9 0.0022 18.1 3.1 2.6 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 CEG49546.1 - 3.2 8.2 8.2 0.77 10.1 3.5 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family SOAR PF16533.5 CEG49546.1 - 5 7.1 15.6 2.6 8.1 1.8 3.8 2 1 0 3 3 3 0 STIM1 Orai1-activating region DUF4140 PF13600.6 CEG49546.1 - 9.6 6.7 16.0 1 9.8 0.5 4.2 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Urb2 PF10441.9 CEG49547.1 - 2.1e-23 83.3 10.9 1.1e-22 81.0 1.9 3.8 3 0 0 3 3 3 2 Urb2/Npa2 family DUF447 PF04289.12 CEG49547.1 - 0.0084 15.9 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF447) DUF2383 PF09537.10 CEG49547.1 - 0.03 14.7 0.1 0.099 13.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) WW PF00397.26 CEG49548.1 - 1.8e-06 27.9 0.1 3.8e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 WW domain FOXO_KIX_bdg PF16675.5 CEG49548.1 - 0.82 10.0 3.8 0.48 10.8 1.1 2.0 2 0 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 Sybindin PF04099.12 CEG49549.1 - 1.2e-46 158.2 0.0 1.4e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CEG49549.1 - 1.1e-05 25.6 0.0 1.3e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Trypsin_2 PF13365.6 CEG49550.1 - 0.0016 19.3 0.0 0.0034 18.3 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEG49550.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Trypsin HTH_Tnp_1 PF01527.20 CEG49551.1 - 4.5e-09 36.5 3.5 6.2e-09 36.1 3.5 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 CEG49551.1 - 0.0074 16.1 0.2 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEG49551.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FAM76 PF16046.5 CEG49551.1 - 0.027 13.8 1.7 0.03 13.7 1.7 1.1 1 0 0 1 1 1 0 FAM76 protein CCDC-167 PF15188.6 CEG49551.1 - 0.061 13.7 6.9 0.093 13.1 6.9 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4005 PF13178.6 CEG49551.1 - 0.21 12.3 2.7 0.26 12.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) DUF498 PF04430.14 CEG49552.1 - 0.042 13.9 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Paralemmin PF03285.15 CEG49552.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Retrotran_gag_2 PF14223.6 CEG49556.1 - 1e-26 93.2 0.0 1.8e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_44 PF14641.6 CEG49556.1 - 0.028 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 AMP-binding PF00501.28 CEG49557.1 - 8e-48 163.1 0.0 1.3e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Na_Ca_ex PF01699.24 CEG49558.1 - 1e-46 158.6 36.7 3.2e-26 92.1 13.6 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Dpy-30 PF05186.13 CEG49561.1 - 3.4e-11 42.6 0.1 6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CEG49561.1 - 0.00025 21.2 0.0 1.7 8.7 0.0 3.3 2 1 0 2 2 2 2 Adenylate kinase NAD_binding_10 PF13460.6 CEG49561.1 - 0.0021 18.0 0.4 0.0021 18.0 0.4 2.1 2 0 0 2 2 2 1 NAD(P)H-binding AAA_22 PF13401.6 CEG49561.1 - 0.061 13.6 0.1 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEG49561.1 - 0.09 13.3 0.1 0.92 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 CEG49561.1 - 0.13 12.6 0.4 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 CEG49561.1 - 0.22 12.0 1.3 1.4 9.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain Kinesin PF00225.23 CEG49563.1 - 1.5e-91 306.8 0.1 1.9e-91 306.5 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG49563.1 - 7.4e-18 64.9 0.0 2.5e-16 60.0 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 CEG49563.1 - 0.0054 16.1 1.0 0.025 13.9 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 CEG49563.1 - 0.12 13.3 0.1 0.12 13.3 0.1 3.4 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Smac_DIABLO PF09057.10 CEG49563.1 - 0.22 10.8 1.8 0.46 9.8 1.8 1.5 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases GIT_CC PF16559.5 CEG49563.1 - 5 7.1 13.4 4.7 7.2 0.3 4.1 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5094 PF17015.5 CEG49563.1 - 5.5 7.1 5.9 12 5.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Retrotrans_gag PF03732.17 CEG49564.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein T2SSJ PF11612.8 CEG49564.1 - 0.077 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J Cas9_a PF18470.1 CEG49565.1 - 0.082 12.4 0.1 0.088 12.3 0.1 1.1 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain DEAD_2 PF06733.15 CEG49566.1 - 4.1e-47 160.1 0.9 8.3e-47 159.1 0.9 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CEG49566.1 - 2.4e-43 148.2 0.0 5.4e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain zf-C3HC4_3 PF13920.6 CEG49566.1 - 2.3e-06 27.4 9.8 2.3e-06 27.4 9.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CEG49566.1 - 1.9e-05 24.5 0.0 0.00099 18.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CEG49566.1 - 7.8e-05 22.7 0.0 0.0033 17.4 0.1 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 CEG49566.1 - 0.00032 20.5 13.4 0.00071 19.4 11.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG49566.1 - 0.0035 17.2 10.9 0.0085 15.9 9.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 PhoH PF02562.16 CEG49566.1 - 0.0055 16.2 0.1 3.2 7.1 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein zf-UDP PF14569.6 CEG49566.1 - 0.009 16.1 2.0 0.025 14.7 2.0 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger DUF3067 PF11267.8 CEG49566.1 - 0.013 16.1 0.0 11 6.7 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) SNF2_N PF00176.23 CEG49566.1 - 0.094 11.4 0.0 0.56 8.9 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_6 PF14835.6 CEG49566.1 - 0.15 11.9 5.4 1.2 9.1 4.7 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CEG49566.1 - 0.18 11.8 10.5 0.7 9.9 10.5 2.1 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CEG49566.1 - 0.23 11.3 10.7 0.92 9.4 10.7 2.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CEG49566.1 - 1.4 9.0 8.4 6.6 6.8 8.4 2.3 1 0 0 1 1 1 0 RING-type zinc-finger UFC1 PF08694.11 CEG49568.1 - 2.2e-83 277.5 0.1 2.4e-83 277.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CEG49568.1 - 0.03 14.0 0.1 0.074 12.7 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 CEG49568.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF2970 PF11174.8 CEG49570.1 - 0.095 12.6 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Orf78 PF06024.12 CEG49570.1 - 0.13 12.6 0.4 0.72 10.2 0.0 2.2 2 1 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 CEG49570.1 - 0.99 10.3 0.0 0.99 10.3 0.0 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ndc80_HEC PF03801.13 CEG49573.1 - 2e-42 144.4 0.9 6.9e-42 142.7 0.0 2.3 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 CEG49573.1 - 0.02 14.9 4.3 0.02 14.9 4.3 4.6 5 2 1 6 6 6 0 Domain of unknown function (DUF5595) ERM PF00769.19 CEG49573.1 - 1.6 8.5 52.7 1.8 8.3 20.5 3.1 2 1 1 3 3 3 0 Ezrin/radixin/moesin family GAS PF13851.6 CEG49573.1 - 2.9 7.2 55.1 0.37 10.1 6.5 3.6 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding LID PF17916.1 CEG49574.1 - 0.091 12.4 1.2 0.45 10.2 0.3 2.3 2 0 0 2 2 2 0 LIM interaction domain (LID) DUF4596 PF15363.6 CEG49574.1 - 0.14 12.4 6.3 1.2 9.4 1.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) SET PF00856.28 CEG49576.1 - 8.9e-20 71.7 0.1 4.9e-19 69.3 0.1 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 CEG49576.1 - 2.2e-08 34.0 6.2 2.2e-08 34.0 6.2 2.0 2 0 0 2 2 2 1 AWS domain Sec10 PF07393.11 CEG49577.1 - 2.5 6.4 6.2 3.3 6.0 6.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Ribosomal_L7Ae PF01248.26 CEG49579.1 - 0.0053 16.5 0.1 0.008 15.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FtsJ PF01728.19 CEG49580.1 - 2.1e-26 93.1 0.0 3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Myotub-related PF06602.14 CEG49581.1 - 1e-128 429.2 0.0 1.5e-128 428.7 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CEG49581.1 - 0.00036 20.4 0.0 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 GRAM domain Y_phosphatase3 PF13350.6 CEG49581.1 - 0.00051 20.1 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEG49581.1 - 0.0049 16.5 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEG49581.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PBP_GOBP PF01395.22 CEG49581.1 - 0.11 12.7 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 PBP/GOBP family FAA_hydrolase PF01557.18 CEG49582.1 - 1.2e-65 221.3 0.0 1.5e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_C1 PF00112.23 CEG49583.1 - 1.2e-53 182.4 6.9 1.7e-53 182.0 6.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CEG49583.1 - 0.00065 18.6 1.1 0.017 14.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family NAD_binding_10 PF13460.6 CEG49583.1 - 0.059 13.3 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding rve PF00665.26 CEG49585.1 - 7e-14 52.0 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEG49585.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_2 PF14223.6 CEG49586.1 - 2.3e-26 92.1 0.0 3.1e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_hydro_81 PF03639.13 CEG49586.1 - 4.3e-21 75.4 0.1 5.7e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Aminotran_1_2 PF00155.21 CEG49588.1 - 1.2e-52 179.3 0.0 1.6e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEG49588.1 - 0.00015 20.4 0.0 0.0003 19.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 CEG49588.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Allinase DUF1084 PF06454.11 CEG49589.1 - 7.3e-43 146.9 11.5 9e-43 146.6 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Mannosyl_trans4 PF15971.5 CEG49591.1 - 0.048 13.5 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase RabGAP-TBC PF00566.18 CEG49592.1 - 2.1e-45 155.1 0.1 3.6e-45 154.2 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain C2 PF00168.30 CEG49592.1 - 2.9e-06 27.5 0.0 7.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain HEPN_LA2681 PF18733.1 CEG49592.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 LA2681-like HEPN ASH PF15780.5 CEG49593.1 - 1.5e-30 105.3 28.3 1.2e-05 25.4 0.1 14.6 16 0 0 16 16 16 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEG49593.1 - 1.8e-15 57.0 4.7 0.00011 22.3 0.1 7.4 7 0 0 7 7 7 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CEG49593.1 - 9.2e-09 35.1 0.8 1.6 8.7 0.0 7.9 10 1 0 10 10 10 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CEG49593.1 - 4.2e-05 23.7 10.0 1.7 9.0 0.0 8.2 8 0 0 8 8 8 1 Transmembrane protein 131-like tRNA_U5-meth_tr PF05958.11 CEG49594.1 - 1.2e-18 67.3 0.0 4e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CEG49594.1 - 3.3e-05 23.7 0.0 8.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEG49594.1 - 4.8e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CEG49594.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 CEG49594.1 - 0.00082 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CEG49594.1 - 0.0026 18.4 0.0 0.0076 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.9 CEG49594.1 - 0.0033 16.6 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 CEG49594.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Fer4_14 PF13394.6 CEG49595.1 - 0.089 12.9 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF131 PF01998.17 CEG49595.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF131 p450 PF00067.22 CEG49598.1 - 6.9e-71 239.4 0.5 8.5e-71 239.1 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 SH3BGR PF04908.15 CEG49600.1 - 0.00018 21.6 0.1 0.00035 20.7 0.1 1.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CEG49600.1 - 0.025 14.8 0.0 0.072 13.3 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin ArdA PF07275.11 CEG49600.1 - 0.03 14.9 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein (ArdA) SUIM_assoc PF16619.5 CEG49600.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 bZIP_1 PF00170.21 CEG49601.1 - 2.6e-09 37.1 8.8 5.6e-09 36.0 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEG49601.1 - 4e-05 23.6 11.0 9.9e-05 22.4 11.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEG49601.1 - 0.016 15.7 6.5 0.016 15.7 6.5 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TFIIA PF03153.13 CEG49601.1 - 0.022 14.8 4.5 0.027 14.5 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SnoaL_2 PF12680.7 CEG49601.1 - 0.08 13.6 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain DHHC PF01529.20 CEG49602.1 - 1.5e-32 112.5 5.5 1.5e-32 112.5 5.5 2.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF2842 PF11003.8 CEG49602.1 - 0.54 10.6 3.1 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) Pkinase PF00069.25 CEG49603.1 - 1.8e-07 30.8 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CEG49604.1 - 2.3e-18 66.5 0.1 2.9e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49604.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE_2 PF02318.16 CEG49605.1 - 0.86 9.8 4.9 2.3 8.4 4.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CEG49605.1 - 2.2 8.5 8.8 5.1 7.3 8.8 1.7 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 CEG49608.1 - 1 9.6 10.3 3 8.1 10.3 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger p450 PF00067.22 CEG49609.1 - 8.8e-73 245.6 2.1 1.1e-72 245.3 2.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CEG49610.1 - 9.2e-70 235.7 0.0 1.1e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OrfB_Zn_ribbon PF07282.11 CEG49611.1 - 0.0026 17.6 2.5 0.0065 16.4 2.5 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain FYVE PF01363.21 CEG49611.1 - 0.05 13.7 9.7 0.12 12.5 9.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger Hydrolase_4 PF12146.8 CEG49615.1 - 0.032 13.5 0.0 1.8 7.7 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 CEG49617.1 - 0.016 14.5 0.0 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CEG49617.1 - 0.088 12.9 0.0 0.25 11.5 0.0 1.8 1 1 0 1 1 1 0 TAP-like protein Peptidase_C48 PF02902.19 CEG49618.1 - 1.3e-15 57.8 0.2 2.5e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YwqJ-deaminase PF14431.6 CEG49621.1 - 0.053 13.7 0.1 0.092 12.9 0.1 1.4 1 1 0 1 1 1 0 YwqJ-like deaminase EF-hand_8 PF13833.6 CEG49623.1 - 1.6e-16 59.9 3.5 1.8e-10 40.5 1.8 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CEG49623.1 - 8.3e-16 56.3 7.9 2.7e-07 29.7 1.5 4.0 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 CEG49623.1 - 1.6e-15 57.3 1.0 1.7e-11 44.4 1.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG49623.1 - 1.2e-11 43.6 1.6 0.00021 21.0 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 CEG49623.1 - 3e-06 27.5 0.1 0.0038 17.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CEG49623.1 - 0.00099 18.5 12.6 0.032 13.8 1.2 3.4 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CEG49623.1 - 0.0045 16.9 0.7 0.064 13.2 0.6 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Retrotran_gag_2 PF14223.6 CEG49627.1 - 6.2e-21 74.5 1.9 7.2e-21 74.3 1.9 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF489 PF04356.12 CEG49628.1 - 0.14 12.1 0.7 0.25 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Linker_histone PF00538.19 CEG49629.1 - 5.6e-18 65.1 0.1 5.6e-18 65.1 0.1 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CEG49629.1 - 2.8 8.0 58.5 0.49 10.4 25.4 2.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 Acyl-CoA_dh_1 PF00441.24 CEG49631.1 - 4.8e-35 121.0 0.1 8.3e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEG49631.1 - 1.2e-26 93.5 0.0 2.6e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEG49631.1 - 1.6e-22 79.5 0.1 3e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEG49631.1 - 9.4e-15 55.1 0.0 2.5e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Bromodomain PF00439.25 CEG49632.1 - 1.2e-18 66.9 0.0 2.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 CEG49632.1 - 2.2e-15 56.6 0.2 5.6e-15 55.3 0.2 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF2098 PF09871.9 CEG49632.1 - 2.6 8.5 6.8 19 5.6 6.8 2.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Chorion_2 PF03964.15 CEG49632.1 - 3.9 8.4 5.3 9.4 7.1 1.0 2.7 2 0 0 2 2 2 0 Chorion family 2 Clr2 PF10383.9 CEG49633.1 - 5.7 7.7 7.0 2.2 9.0 0.1 2.6 2 1 0 2 2 2 0 Transcription-silencing protein Clr2 HTH_23 PF13384.6 CEG49634.1 - 0.079 12.8 2.2 0.13 12.1 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 CEG49634.1 - 0.088 12.8 0.5 6 6.9 0.0 3.2 2 0 0 2 2 2 0 HTH domain HTH_AsnC-type PF13404.6 CEG49634.1 - 0.1 12.4 1.7 0.31 10.9 0.2 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF1192 PF06698.11 CEG49634.1 - 0.11 12.6 13.4 4.6 7.4 0.4 5.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Shugoshin_N PF07558.11 CEG49634.1 - 6.7 6.7 11.2 32 4.5 0.7 4.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region FAD-oxidase_C PF02913.19 CEG49635.1 - 5.9e-60 203.0 0.0 8.3e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEG49635.1 - 1.5e-37 128.4 1.3 2.4e-37 127.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_2 PF12756.7 CEG49636.1 - 1.1e-31 109.1 12.9 4.4e-27 94.4 3.9 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEG49636.1 - 6.5e-07 29.5 1.5 6.5e-07 29.5 1.5 4.2 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEG49636.1 - 3.4e-05 24.1 2.4 3.4e-05 24.1 2.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2024 PF09630.10 CEG49636.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Phage_lambda_P PF06992.11 CEG49636.1 - 0.085 12.6 0.5 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Replication protein P zf-C2H2_4 PF13894.6 CEG49636.1 - 0.15 13.0 0.4 0.15 13.0 0.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger TMEM156 PF15106.6 CEG49636.1 - 0.17 11.3 3.4 0.33 10.3 3.4 1.4 1 0 0 1 1 1 0 TMEM156 protein family DUF1764 PF08576.10 CEG49639.1 - 8.8e-20 71.5 8.9 8.8e-20 71.5 8.9 2.9 1 1 1 2 2 1 1 Eukaryotic protein of unknown function (DUF1764) KdpC PF02669.15 CEG49639.1 - 0.25 11.2 3.0 0.31 10.8 0.1 2.0 1 1 0 2 2 2 0 K+-transporting ATPase, c chain Asp-B-Hydro_N PF05279.11 CEG49639.1 - 0.27 11.2 17.3 0.38 10.8 17.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lambda_Bor PF06291.11 CEG49639.1 - 0.28 11.2 3.2 0.45 10.6 0.1 2.5 3 0 0 3 3 3 0 Bor protein RR_TM4-6 PF06459.12 CEG49639.1 - 0.46 10.3 21.2 0.56 10.0 21.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CelTOS PF18659.1 CEG49639.1 - 0.63 10.5 8.4 0.1 13.1 4.2 1.8 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites HGD-D PF06050.13 CEG49639.1 - 3.8 7.2 7.3 3.8 7.2 6.3 1.3 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component AAA_23 PF13476.6 CEG49639.1 - 4.7 7.7 20.9 6.4 7.2 20.9 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEG49639.1 - 4.8 6.9 17.0 6.6 6.4 17.0 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CEG49639.1 - 6.4 4.5 9.6 7.4 4.4 9.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNApol_Exo PF18136.1 CEG49639.1 - 8.2 5.5 10.7 13 4.8 10.7 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CHIP_TPR_N PF18391.1 CEG49639.1 - 9.6 7.1 21.7 7.3 7.4 7.5 2.8 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Ras PF00071.22 CEG49640.1 - 1.4e-51 174.3 0.3 2e-51 173.8 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG49640.1 - 1.1e-29 103.0 1.3 1.2e-29 103.0 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG49640.1 - 1e-09 38.1 0.2 2.1e-09 37.1 0.2 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG49640.1 - 7.7e-06 26.0 0.2 1.4e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG49640.1 - 0.00016 21.7 0.2 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CEG49640.1 - 0.0025 18.1 0.1 0.013 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEG49640.1 - 0.0042 17.5 0.1 0.0068 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 CEG49640.1 - 0.0043 16.3 0.1 0.0056 16.0 0.1 1.1 1 0 0 1 1 1 1 KAP family P-loop domain ABC_tran PF00005.27 CEG49640.1 - 0.018 15.6 0.2 0.042 14.4 0.2 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 CEG49640.1 - 0.019 14.7 0.0 0.064 13.0 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CEG49640.1 - 0.023 14.2 0.2 0.074 12.6 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CEG49640.1 - 0.031 14.0 0.2 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CEG49640.1 - 0.041 13.3 0.6 0.088 12.2 0.0 1.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEG49640.1 - 0.053 12.9 0.1 0.32 10.3 0.0 2.1 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CEG49640.1 - 0.066 12.6 0.1 0.2 11.1 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 CEG49640.1 - 0.09 12.8 0.1 0.44 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEG49640.1 - 0.11 12.5 0.1 0.31 11.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 CEG49640.1 - 0.23 11.2 1.2 0.44 10.3 0.6 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IMPDH PF00478.25 CEG49643.1 - 4.7e-82 275.7 1.6 9.2e-82 274.8 1.6 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Mito_carr PF00153.27 CEG49643.1 - 1e-50 169.6 3.7 2.2e-16 59.6 0.0 4.5 4 0 0 4 4 4 3 Mitochondrial carrier protein FMN_dh PF01070.18 CEG49643.1 - 8.8e-05 21.7 1.3 0.00015 20.9 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase dCache_3 PF14827.6 CEG49643.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Glyco_transf_22 PF03901.17 CEG49644.1 - 2.7e-50 171.8 26.4 3.6e-50 171.4 26.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3096 PF11295.8 CEG49644.1 - 3.7 7.3 9.3 41 3.9 0.7 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) PITH PF06201.13 CEG49646.1 - 4.4e-38 130.9 0.9 5.1e-38 130.7 0.9 1.0 1 0 0 1 1 1 1 PITH domain LRR_4 PF12799.7 CEG49649.1 - 2.1e-07 31.2 7.2 9.1e-05 22.8 0.2 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG49649.1 - 0.00019 21.1 4.6 0.15 11.9 0.9 2.9 1 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 CEG49649.1 - 0.0047 16.5 1.4 0.0097 15.4 1.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeat DUF1081 PF06448.11 CEG49649.1 - 0.039 14.3 1.4 0.086 13.2 0.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1081) Coa1 PF08695.10 CEG49652.1 - 1.7e-07 31.0 0.1 3.3e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Phospholamban PF04272.14 CEG49652.1 - 0.0045 16.4 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Phospholamban PUA_2 PF14306.6 CEG49652.1 - 0.069 12.8 0.1 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 PUA-like domain MARVEL PF01284.23 CEG49653.1 - 1.2e-08 35.2 17.1 1.7e-08 34.6 17.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.23 CEG49654.1 - 3.8e-09 36.7 15.1 3.8e-09 36.7 15.1 2.4 2 0 0 2 2 2 2 Membrane-associating domain ETF PF01012.21 CEG49655.1 - 1.3e-34 119.7 6.3 1.9e-34 119.1 6.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CEG49655.1 - 2.7e-24 85.0 0.8 5.5e-24 84.0 0.2 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain DAD PF02109.16 CEG49656.1 - 6.1e-39 132.7 1.8 6.6e-39 132.6 1.8 1.0 1 0 0 1 1 1 1 DAD family MNHE PF01899.16 CEG49656.1 - 0.11 12.2 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF2207 PF09972.9 CEG49656.1 - 0.16 10.7 0.4 0.16 10.7 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EGF_2 PF07974.13 CEG49659.1 - 7.8e-14 51.7 64.1 2.1e-05 24.8 12.9 5.7 5 1 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 CEG49659.1 - 0.0052 16.9 25.9 0.018 15.1 10.7 4.7 4 1 1 5 5 5 3 Laminin EGF domain EGF PF00008.27 CEG49659.1 - 0.066 13.5 54.7 0.11 12.8 6.5 5.8 6 0 0 6 6 6 0 EGF-like domain EGF_Tenascin PF18720.1 CEG49659.1 - 0.39 10.8 0.2 0.39 10.8 0.2 6.5 7 0 0 7 7 7 0 Tenascin EGF domain RNA_pol_Rpb6 PF01192.22 CEG49660.1 - 2.7e-16 59.2 0.3 2.7e-16 59.2 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 AAA_14 PF13173.6 CEG49660.1 - 0.1 12.6 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.6 CEG49662.1 - 7.9e-07 29.7 0.0 1.5e-05 25.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CEG49662.1 - 4.3e-05 23.1 0.0 8.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEG49662.1 - 0.00046 19.8 0.0 0.074 12.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 CEG49662.1 - 0.00081 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG49662.1 - 0.0011 19.6 0.0 0.0041 17.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEG49662.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEG49662.1 - 0.12 13.2 0.0 0.51 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEG49662.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 CEG49663.1 - 8.2e-19 67.2 0.0 1.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Filo_VP35 PF02097.15 CEG49664.1 - 0.045 12.8 0.1 0.055 12.5 0.1 1.2 1 0 0 1 1 1 0 Filoviridae VP35 PAS_10 PF13596.6 CEG49664.1 - 0.058 14.0 0.5 0.13 12.9 0.3 1.7 2 0 0 2 2 2 0 PAS domain PIH1 PF08190.12 CEG49667.1 - 9.2e-36 122.8 0.3 1.6e-35 122.0 0.3 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain IKKbetaNEMObind PF12179.8 CEG49667.1 - 0.03 14.4 0.7 4.8 7.3 1.0 3.0 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain PIH1_CS PF18201.1 CEG49668.1 - 6.2e-17 61.8 0.0 3.4e-16 59.5 0.0 2.2 2 1 0 2 2 2 1 PIH1 CS-like domain WD40 PF00400.32 CEG49669.1 - 3.8e-12 46.5 7.3 0.066 14.1 0.8 6.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49669.1 - 5.9e-06 26.5 0.4 0.11 12.8 0.0 5.2 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CEG49669.1 - 0.00073 19.2 0.3 0.022 14.3 0.0 2.9 3 1 0 3 3 3 1 PQQ-like domain Exo_endo_phos PF03372.23 CEG49670.1 - 5.6e-29 101.3 0.0 7.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1959 PF09218.10 CEG49670.1 - 0.08 13.1 0.3 0.08 13.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) MAPEG PF01124.18 CEG49671.1 - 3.6e-11 43.1 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 MAPEG family Alg14 PF08660.11 CEG49672.1 - 2.7e-49 167.4 0.0 5.6e-49 166.4 0.0 1.5 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like CN_hydrolase PF00795.22 CEG49673.1 - 1.7e-31 109.5 0.0 2.7e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MORN PF02493.20 CEG49673.1 - 1.1e-23 81.7 36.5 2.6e-06 27.0 2.1 6.6 6 0 0 6 6 6 6 MORN repeat Ribosomal_S15 PF00312.22 CEG49674.1 - 6.3e-20 71.2 0.9 9.5e-20 70.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 TruB_N PF01509.18 CEG49674.1 - 0.098 13.0 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) PhetRS_B1 PF18262.1 CEG49674.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PH PF00169.29 CEG49675.1 - 1e-10 42.0 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG49675.1 - 0.05 14.0 0.0 0.05 14.0 0.0 4.0 3 2 0 3 3 3 0 Pleckstrin homology domain zf-RanBP PF00641.18 CEG49675.1 - 0.12 11.7 1.2 0.22 10.9 1.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PH_9 PF15410.6 CEG49675.1 - 0.89 9.9 0.0 0.89 9.9 0.0 4.0 3 2 0 3 3 3 0 Pleckstrin homology domain SAP30_Sin3_bdg PF13867.6 CEG49676.1 - 8.2e-11 42.1 0.1 1.5e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 CEG49676.1 - 5.9e-06 26.1 8.1 5.9e-06 26.1 8.1 2.7 3 0 0 3 3 3 1 PHD-finger Forkhead PF00250.18 CEG49676.1 - 7.7e-06 26.1 0.0 2.4e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Forkhead domain zf-HC5HC2H PF13771.6 CEG49676.1 - 0.072 13.4 9.6 0.029 14.6 5.5 2.5 2 1 0 2 2 2 0 PHD-like zinc-binding domain CS PF04969.16 CEG49677.1 - 1.3e-06 29.3 0.3 1.3e-06 29.3 0.3 1.6 2 0 0 2 2 2 1 CS domain ANAPC10 PF03256.16 CEG49678.1 - 0.00043 20.0 0.4 0.0011 18.7 0.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DnaJ PF00226.31 CEG49682.1 - 4.8e-20 71.4 0.2 7e-20 70.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain Nuc_sug_transp PF04142.15 CEG49683.1 - 0.00088 18.5 0.1 0.0016 17.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CEG49683.1 - 0.0035 16.7 2.6 0.0081 15.5 2.6 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 CEG49683.1 - 0.0041 16.4 1.8 0.0041 16.4 1.8 2.0 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 CEG49683.1 - 0.024 14.7 0.3 0.062 13.3 0.3 1.7 1 0 0 1 1 1 0 Putative transmembrane family 234 EamA PF00892.20 CEG49683.1 - 0.035 14.3 21.9 0.038 14.2 6.9 3.2 3 0 0 3 3 3 0 EamA-like transporter family PMP22_Claudin PF00822.20 CEG49683.1 - 5.8 6.7 12.2 30 4.5 8.4 2.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family EIIBC-GUT_N PF03612.14 CEG49685.1 - 0.27 10.9 1.3 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Ribosomal_L31e PF01198.19 CEG49686.1 - 0.056 13.7 0.2 0.085 13.1 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L31e DUF3136 PF11334.8 CEG49688.1 - 0.14 12.0 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Bac_chlorC PF02043.17 CEG49690.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Carb_bind PF10645.9 CEG49690.1 - 0.47 10.7 6.7 8.6 6.7 1.1 2.7 2 0 0 2 2 2 0 Carbohydrate binding Sororin PF09666.10 CEG49690.1 - 1.1 9.4 5.6 0.31 11.2 0.2 2.4 2 0 0 2 2 2 0 Sororin protein Vps54_N PF10475.9 CEG49690.1 - 5.5 6.2 16.2 0.43 9.8 5.7 2.2 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DHHC PF01529.20 CEG49691.1 - 2e-10 40.9 16.4 2e-10 40.9 16.4 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase ADH_N PF08240.12 CEG49691.1 - 0.037 13.9 2.7 0.054 13.4 2.7 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain TGT PF01702.18 CEG49692.1 - 6.1e-74 249.3 0.0 7.3e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF4413 PF14372.6 CEG49693.1 - 3.6e-05 24.0 0.1 0.00014 22.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) 5_3_exonuc PF01367.20 CEG49693.1 - 0.11 13.1 0.3 0.43 11.2 0.0 2.1 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DUF687 PF05095.12 CEG49694.1 - 0.035 12.6 0.1 0.046 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) EVI2A PF05399.11 CEG49695.1 - 0.016 14.8 0.6 0.016 14.8 0.6 1.7 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF4514 PF14986.6 CEG49695.1 - 0.027 14.4 0.2 0.052 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) TMEM154 PF15102.6 CEG49695.1 - 0.9 9.4 9.4 2.1 8.3 7.6 2.3 1 1 0 1 1 1 0 TMEM154 protein family Macoilin PF09726.9 CEG49695.1 - 7.7 4.9 5.1 8.9 4.7 5.1 1.1 1 0 0 1 1 1 0 Macoilin family SL4P PF17618.2 CEG49696.1 - 0.092 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Trypsin PF00089.26 CEG49697.1 - 0.016 15.1 1.6 0.031 14.1 0.7 1.7 1 1 1 2 2 2 0 Trypsin MIP PF00230.20 CEG49701.1 - 2.1e-25 89.8 2.2 2.6e-25 89.5 2.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_4_2 PF04020.13 CEG49701.1 - 0.01 16.5 2.1 0.01 16.5 2.1 2.1 2 1 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV zf-C3HC4_2 PF13923.6 CEG49702.1 - 2.8e-06 27.0 5.6 4e-06 26.6 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 CEG49702.1 - 1.8e-05 24.7 2.7 4.1e-05 23.5 2.5 1.6 2 0 0 2 2 2 1 PX domain zf-rbx1 PF12678.7 CEG49702.1 - 7.3e-05 23.0 0.2 7.3e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEG49702.1 - 0.00015 22.0 3.5 0.00028 21.2 0.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CEG49702.1 - 0.00022 21.1 2.3 0.00022 21.1 2.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG49702.1 - 0.00024 20.9 0.3 0.00024 20.9 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEG49702.1 - 0.0035 17.0 0.5 0.0035 17.0 0.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEG49702.1 - 0.0054 16.7 0.4 0.024 14.7 0.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CEG49702.1 - 0.057 13.0 2.4 0.19 11.3 0.9 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 CEG49702.1 - 2.3 8.3 7.0 1 9.4 1.9 2.5 2 0 0 2 2 2 0 Zinc-finger Kinesin PF00225.23 CEG49703.1 - 1.4e-78 264.1 0.6 2.7e-78 263.2 0.6 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG49703.1 - 9.7e-13 48.3 0.2 3.4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Endotoxin_mid PF09131.10 CEG49703.1 - 0.0051 16.5 0.3 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Bacillus thuringiensis delta-Endotoxin, middle domain DUF87 PF01935.17 CEG49703.1 - 0.068 13.3 0.0 0.068 13.3 0.0 2.1 3 0 0 3 3 3 0 Helicase HerA, central domain SPARC_Ca_bdg PF10591.9 CEG49703.1 - 0.1 12.9 0.5 3.6 7.9 0.2 2.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_30 PF13604.6 CEG49703.1 - 0.16 11.7 2.6 1.8 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.26 CEG49704.1 - 2.2e-15 56.8 0.9 3.5e-15 56.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEG49704.1 - 1.6e-08 35.6 0.1 3.9e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEG49704.1 - 4.3e-08 33.0 0.3 2.5e-07 30.5 0.0 2.5 4 0 0 4 4 4 1 Alcohol dehydrogenase GroES-like domain ATP-synt_C PF00137.21 CEG49706.1 - 1.4e-36 124.6 34.9 1.6e-23 82.8 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Med22 PF06179.12 CEG49707.1 - 2.8e-19 69.3 1.0 3.4e-19 69.0 1.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex ApoLp-III PF07464.11 CEG49707.1 - 0.0028 17.8 0.6 0.086 12.9 0.5 2.1 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 CEG49707.1 - 0.094 12.6 0.2 0.21 11.4 0.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSBP1 PF06825.12 CEG49707.1 - 0.11 12.3 2.2 0.17 11.8 0.2 2.3 3 1 0 3 3 3 0 Heat shock factor binding protein 1 YtxH PF12732.7 CEG49707.1 - 0.22 12.1 1.3 1.5 9.4 1.3 2.2 1 1 0 1 1 1 0 YtxH-like protein SNF5 PF04855.12 CEG49708.1 - 5.7e-44 150.7 2.2 1.5e-22 80.6 0.0 2.5 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 HMG_box PF00505.19 CEG49708.1 - 3e-14 53.2 1.0 5.8e-14 52.3 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEG49708.1 - 1.8e-06 28.5 1.4 4.6e-06 27.1 1.4 1.7 1 0 0 1 1 1 1 HMG-box domain HTH_31 PF13560.6 CEG49708.1 - 0.00025 21.4 0.1 0.00052 20.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 CEG49708.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 CEG49708.1 - 0.053 13.3 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_19 PF12844.7 CEG49708.1 - 0.13 12.4 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DDT PF02791.17 CEG49708.1 - 0.15 12.4 0.3 0.44 10.9 0.3 1.7 1 0 0 1 1 1 0 DDT domain ORF6C PF10552.9 CEG49712.1 - 0.04 14.0 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 ORF6C domain DUF1725 PF08333.11 CEG49714.1 - 0.0045 16.6 1.8 0.0045 16.6 1.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1725) AAA PF00004.29 CEG49715.1 - 3e-40 137.7 0.0 6.2e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEG49715.1 - 3.1e-10 39.7 0.2 6.7e-10 38.6 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEG49715.1 - 9.3e-10 38.3 0.1 2.9e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 CEG49715.1 - 4.7e-06 26.9 0.2 0.0063 16.8 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 CEG49715.1 - 8.8e-06 25.9 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEG49715.1 - 5.3e-05 22.5 0.0 8.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CEG49715.1 - 0.00013 22.0 0.1 0.00077 19.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEG49715.1 - 0.00026 21.4 0.3 0.0033 17.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEG49715.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CEG49715.1 - 0.019 15.3 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CEG49715.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CEG49715.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CEG49715.1 - 0.025 13.9 0.1 0.35 10.2 0.1 2.2 1 1 0 2 2 2 0 KaiC AAA_3 PF07726.11 CEG49715.1 - 0.034 14.0 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEG49715.1 - 0.068 12.9 0.2 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEG49715.1 - 0.077 12.7 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 CEG49715.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEG49715.1 - 0.12 12.2 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 CEG49715.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CEG49715.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 CEG49715.1 - 0.16 11.6 1.2 0.39 10.4 0.1 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 CEG49715.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Microcin PF03526.13 CEG49720.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Colicin E1 (microcin) immunity protein MIP PF00230.20 CEG49722.1 - 1.2e-56 192.0 5.2 1.4e-56 191.8 5.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2157 PF09925.9 CEG49722.1 - 0.0063 16.3 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2157) Phage_holin_5_2 PF16079.5 CEG49722.1 - 0.056 13.8 0.1 0.056 13.8 0.1 2.9 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF1418 PF07214.12 CEG49722.1 - 0.44 10.4 1.3 13 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Tad PF13400.6 CEG49722.1 - 2.7 8.4 5.3 28 5.1 0.3 2.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Ephrin_rec_like PF07699.13 CEG49723.1 - 0.029 14.2 3.1 0.076 12.8 3.1 1.8 1 0 0 1 1 1 0 Putative ephrin-receptor like Erf4 PF10256.9 CEG49723.1 - 0.13 12.4 0.0 0.82 9.8 0.0 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family DIM1 PF02966.16 CEG49724.1 - 2e-66 221.8 0.1 2.2e-66 221.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CEG49724.1 - 0.0033 17.4 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin NDK PF00334.19 CEG49725.1 - 1.2e-42 145.1 0.0 2.6e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CEG49725.1 - 0.0002 21.2 0.3 0.00065 19.5 0.3 1.9 1 1 0 1 1 1 1 DUF1126 PH-like domain Chromo PF00385.24 CEG49726.1 - 0.002 18.0 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEG49726.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Arf PF00025.21 CEG49728.1 - 4.2e-11 42.6 0.0 5.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEG49728.1 - 1.8e-10 41.1 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEG49728.1 - 2.2e-08 33.9 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEG49728.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEG49728.1 - 0.0027 16.9 0.0 0.87 8.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 CEG49728.1 - 0.011 16.2 0.0 0.017 15.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEG49728.1 - 0.016 15.4 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CEG49728.1 - 0.023 14.3 0.0 0.78 9.2 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CEG49728.1 - 0.025 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CEG49728.1 - 0.026 15.0 0.2 0.052 14.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CEG49728.1 - 0.043 13.2 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CEG49728.1 - 0.065 12.9 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEG49728.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CEG49728.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.6 1 1 0 1 1 1 0 Dynamin family CobU PF02283.16 CEG49728.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Med10 PF09748.9 CEG49729.1 - 1.2e-14 54.4 0.0 1.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIP5K PF01504.18 CEG49730.1 - 6.8e-70 235.4 0.0 1.2e-69 234.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 CEG49730.1 - 0.0009 18.6 4.7 0.0009 18.6 4.7 2.2 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Phage_holin_3_6 PF07332.11 CEG49730.1 - 0.21 11.7 3.9 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 CEG49730.1 - 1.5 7.5 9.8 0.37 9.5 1.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tmemb_55A PF09788.9 CEG49730.1 - 5 6.1 5.9 1.4 7.9 0.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 55A zf-HC5HC2H_2 PF13832.6 CEG49731.1 - 3.9e-26 91.4 30.5 3.8e-14 52.8 5.3 3.5 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEG49731.1 - 9.3e-24 83.5 35.8 6.6e-13 48.7 12.2 4.3 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CEG49731.1 - 1.9e-09 36.9 3.1 1.9e-09 36.9 3.1 3.9 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 CEG49731.1 - 3.4e-08 33.2 44.1 3.1e-07 30.2 7.5 4.8 5 0 0 5 5 5 3 PHD-finger Ada3 PF10198.9 CEG49731.1 - 0.004 17.3 0.4 0.004 17.3 0.4 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Prok-RING_1 PF14446.6 CEG49731.1 - 0.005 16.7 2.9 0.005 16.7 2.9 4.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 CLZ PF16526.5 CEG49731.1 - 0.035 14.5 0.1 0.17 12.2 0.1 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLUF PF04940.12 CEG49731.1 - 0.42 10.8 1.7 0.68 10.1 0.1 2.2 3 0 0 3 3 3 0 Sensors of blue-light using FAD LRR_4 PF12799.7 CEG49732.1 - 1.3e-20 73.2 13.9 1.2e-07 31.9 0.3 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEG49732.1 - 1.6e-11 43.8 17.9 5.4e-05 22.9 0.1 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CEG49732.1 - 1e-06 28.3 3.2 0.00025 20.6 0.9 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CEG49732.1 - 0.0049 16.8 12.9 6.2 7.1 0.1 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CEG49732.1 - 0.57 10.9 15.6 6.7 7.7 0.9 6.3 6 2 0 6 6 6 0 Leucine Rich Repeat IRK_C PF17655.1 CEG49734.1 - 2.9e-25 88.9 0.1 1.9e-12 47.1 0.1 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CEG49734.1 - 4.6e-11 42.7 4.5 4.8e-10 39.4 4.5 2.3 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CEG49734.1 - 0.089 12.8 7.9 0.18 11.8 7.9 1.5 1 0 0 1 1 1 0 Ion channel PapB PF03333.13 CEG49735.1 - 0.0019 18.2 4.2 1.2 9.2 0.1 4.4 4 0 0 4 4 4 2 Adhesin biosynthesis transcription regulatory protein DNA_primase_S PF01896.19 CEG49739.1 - 0.024 14.7 0.1 0.027 14.5 0.1 1.1 1 0 0 1 1 1 0 DNA primase small subunit Integrase_DNA PF02920.15 CEG49739.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase Peptidase_S64 PF08192.11 CEG49740.1 - 0.01 14.4 0.4 0.012 14.1 0.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 RXLR PF16810.5 CEG49740.1 - 0.036 14.5 4.0 0.16 12.4 4.0 2.0 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity HTH_3 PF01381.22 CEG49740.1 - 0.12 12.5 0.1 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix Histone_HNS PF00816.21 CEG49740.1 - 0.69 10.8 3.8 3.8 8.4 3.8 2.0 1 1 1 2 2 2 0 H-NS histone family BRE1 PF08647.11 CEG49740.1 - 1.2 9.2 7.4 0.14 12.3 2.8 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TRAM_LAG1_CLN8 PF03798.16 CEG49741.1 - 1.6e-28 99.8 17.5 2.4e-28 99.3 17.5 1.2 1 0 0 1 1 1 1 TLC domain CrgA PF06781.12 CEG49741.1 - 0.0013 18.7 0.8 0.048 13.7 0.4 2.9 2 0 0 2 2 2 1 Cell division protein CrgA DUF2627 PF11118.8 CEG49741.1 - 0.81 10.3 10.4 0.27 11.9 1.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) BLOC1_2 PF10046.9 CEG49746.1 - 0.0091 16.3 3.1 1 9.7 0.1 3.3 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 PMP1_2 PF08114.11 CEG49747.1 - 0.25 11.1 0.2 0.65 9.8 0.2 1.6 1 0 0 1 1 1 0 ATPase proteolipid family Syntaxin-6_N PF09177.11 CEG49747.1 - 0.37 11.4 5.6 5.1 7.7 1.2 3.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Porin_OmpL1 PF11389.8 CEG49749.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.0 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Complex1_LYR PF05347.15 CEG49754.1 - 3.1e-05 23.9 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EF-G-binding_N PF07299.11 CEG49754.1 - 0.046 14.2 1.6 0.19 12.3 0.5 2.0 1 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Endotoxin_C2 PF18449.1 CEG49754.1 - 0.057 13.7 0.3 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Delta endotoxin GBP PF02263.19 CEG49755.1 - 4.6e-18 65.4 0.1 4.6e-18 65.4 0.1 3.7 4 0 0 4 4 4 1 Guanylate-binding protein, N-terminal domain Seadorna_VP6 PF07407.11 CEG49755.1 - 0.1 11.5 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 Seadornavirus VP6 protein FAA_hydro_N_2 PF18288.1 CEG49755.1 - 1.2 9.6 5.7 1.4 9.4 0.1 3.8 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 ZYG-11_interact PF05884.12 CEG49755.1 - 2.9 7.2 14.5 0.039 13.4 0.4 3.3 2 1 0 2 2 2 0 Interactor of ZYG-11 GCFC PF07842.12 CEG49756.1 - 5.3e-06 26.2 0.4 1.6e-05 24.7 0.4 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein B56 PF01603.20 CEG49760.1 - 1.5e-11 43.9 0.3 2.5e-11 43.2 0.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase_Tyr PF07714.17 CEG49762.1 - 9.6e-53 179.1 0.0 1.3e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG49762.1 - 8.2e-51 172.9 0.0 2.1e-50 171.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain EGF_2 PF07974.13 CEG49762.1 - 0.00086 19.6 4.3 0.00086 19.6 4.3 17.2 8 4 3 11 11 11 3 EGF-like domain Haspin_kinase PF12330.8 CEG49762.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain EGF PF00008.27 CEG49762.1 - 0.0069 16.7 12.0 0.0069 16.7 12.0 14.5 15 0 0 15 15 15 6 EGF-like domain hEGF PF12661.7 CEG49762.1 - 0.009 16.6 6.4 0.009 16.6 6.4 14.3 14 1 0 14 14 14 6 Human growth factor-like EGF Pkinase_fungal PF17667.1 CEG49762.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEG49762.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG49762.1 - 0.24 10.7 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TAFII28 PF04719.14 CEG49763.1 - 9.5e-24 83.3 0.0 1.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CDC45 PF02724.14 CEG49763.1 - 0.054 11.8 1.7 0.049 11.9 1.7 1.0 1 0 0 1 1 1 0 CDC45-like protein TGFb_propeptide PF00688.18 CEG49763.1 - 0.073 12.8 2.0 0.095 12.4 2.0 1.1 1 0 0 1 1 1 0 TGF-beta propeptide RRN3 PF05327.11 CEG49763.1 - 2.7 6.4 8.9 3 6.3 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spidroin_MaSp PF11260.8 CEG49766.1 - 0.078 13.3 0.2 0.091 13.1 0.2 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 FYVE PF01363.21 CEG49768.1 - 1.9e-07 31.1 8.7 1.9e-07 31.1 8.7 2.7 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_5 PF14634.6 CEG49768.1 - 6.9 6.7 11.4 25 4.9 8.4 3.2 2 1 1 3 3 3 0 zinc-RING finger domain DUF2000 PF09391.10 CEG49771.1 - 0.005 16.7 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2000) Peroxidase_2 PF01328.17 CEG49773.1 - 1.1e-36 127.1 0.1 2.5e-36 125.9 0.0 1.6 1 1 1 2 2 2 1 Peroxidase, family 2 PAS_3 PF08447.12 CEG49776.1 - 3.9e-09 36.7 0.0 7.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CEG49776.1 - 2.4e-06 27.5 0.4 4.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold bZIP_2 PF07716.15 CEG49776.1 - 0.00011 22.2 1.8 0.00021 21.3 1.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEG49776.1 - 0.00013 22.0 4.8 0.00022 21.2 4.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAS_11 PF14598.6 CEG49776.1 - 0.025 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain Carb_anhydrase PF00194.21 CEG49779.1 - 5.2e-35 121.2 0.1 7.1e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pkinase PF00069.25 CEG49780.1 - 4.1e-65 219.8 0.0 2.6e-63 213.8 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49780.1 - 8.2e-30 103.9 0.0 1.1e-28 100.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG49780.1 - 3.3e-06 26.6 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Arb2 PF09757.9 CEG49780.1 - 2.4e-05 23.6 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Haspin_kinase PF12330.8 CEG49780.1 - 0.0077 15.2 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG49780.1 - 0.066 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carb_anhydrase PF00194.21 CEG49781.1 - 6.8e-45 153.6 0.4 8.5e-45 153.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Gly-zipper_Omp PF13488.6 CEG49782.1 - 0.021 14.8 0.6 0.028 14.4 0.6 1.2 1 0 0 1 1 1 0 Glycine zipper Ion_trans PF00520.31 CEG49784.1 - 3e-100 334.5 94.3 6.6e-27 94.3 21.3 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CEG49784.1 - 2e-09 37.1 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 CEG49784.1 - 0.054 13.3 1.7 0.21 11.5 1.7 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pirin PF02678.16 CEG49785.1 - 2.6e-28 98.1 0.0 6.3e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CEG49785.1 - 4.2e-27 94.5 0.1 1.4e-26 92.8 0.1 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 CEG49785.1 - 0.00067 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Myb_DNA-binding PF00249.31 CEG49788.1 - 5e-12 45.8 0.1 9.7e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEG49788.1 - 0.016 15.4 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain WD40 PF00400.32 CEG49789.1 - 1.2e-30 105.1 10.8 3.7e-07 30.7 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG49789.1 - 4.4e-13 49.3 0.1 0.0047 17.2 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEG49789.1 - 0.0001 22.3 0.2 0.18 11.7 0.1 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Aa_trans PF01490.18 CEG49790.1 - 7.1e-73 245.7 29.4 8.2e-73 245.4 29.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1656 PF07869.12 CEG49790.1 - 0.015 15.3 0.5 0.015 15.3 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Oxidored_q2 PF00420.24 CEG49790.1 - 2.5 7.8 8.0 10 5.8 8.0 2.0 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PCNA_C PF02747.15 CEG49791.1 - 1e-51 174.4 0.0 6.3e-51 171.9 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CEG49791.1 - 2.2e-50 169.6 0.3 4.1e-50 168.7 0.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 CEG49791.1 - 7.3e-05 22.3 0.0 9.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 CEG49791.1 - 0.00046 19.3 0.0 0.00074 18.7 0.0 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 ADP_ribosyl_GH PF03747.14 CEG49795.1 - 2.9e-20 73.2 0.0 5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DEP PF00610.21 CEG49795.1 - 2.1e-19 69.4 0.3 4.7e-19 68.2 0.3 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AAA_lid_7 PF17867.1 CEG49795.1 - 0.081 13.1 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Midasin AAA lid domain FG-GAP_2 PF14312.6 CEG49796.1 - 1.1e-74 246.5 63.4 3.9e-11 43.0 0.2 16.6 16 1 0 16 16 16 14 FG-GAP repeat Calx-beta PF03160.14 CEG49796.1 - 3.8e-11 43.1 0.4 3.6e-05 23.9 0.0 4.5 3 1 0 3 3 3 2 Calx-beta domain DUF3915 PF13054.6 CEG49797.1 - 0.11 12.4 4.5 4.4 7.3 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PA PF02225.22 CEG49799.1 - 3.9e-08 33.2 0.0 8.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF640 PF04852.12 CEG49799.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Minor_capsid_2 PF11114.8 CEG49799.1 - 0.033 14.2 0.4 5.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Minor capsid protein PTP_tm PF18861.1 CEG49799.1 - 0.085 12.8 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Retrotran_gag_3 PF14244.6 CEG49800.1 - 0.2 11.5 0.5 0.45 10.4 0.1 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 CEG49801.1 - 3.8e-18 66.0 0.0 4e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEG49801.1 - 0.022 14.3 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_37 PF13744.6 CEG49802.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Med31 PF05669.12 CEG49804.1 - 0.028 14.4 0.3 0.065 13.2 0.3 1.7 1 0 0 1 1 1 0 SOH1 DUF4238 PF14022.6 CEG49804.1 - 0.05 13.1 0.5 0.18 11.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) Aminotran_1_2 PF00155.21 CEG49805.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEG49805.1 - 2.6e-06 26.6 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEG49805.1 - 2.1e-05 23.2 0.0 3.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEG49805.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cupin_8 PF13621.6 CEG49806.1 - 8.1e-40 137.1 3.5 1.1e-39 136.7 3.5 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEG49806.1 - 1.8e-05 24.4 1.6 2.8e-05 23.7 1.1 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CEG49806.1 - 0.00017 22.0 0.7 0.00049 20.5 0.7 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_3 PF05899.12 CEG49806.1 - 0.029 14.0 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 CEG49806.1 - 0.033 13.8 0.1 0.21 11.2 0.0 2.3 3 0 0 3 3 3 0 Cupin Cupin_2 PF07883.11 CEG49806.1 - 0.082 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Peptidase_C1 PF00112.23 CEG49808.1 - 2.2e-40 139.1 3.5 1.6e-39 136.3 3.5 2.0 1 1 0 1 1 1 1 Papain family cysteine protease Phage_holin_2_2 PF10746.9 CEG49808.1 - 0.017 14.7 0.5 0.046 13.4 0.5 1.6 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Peptidase_C1_2 PF03051.15 CEG49808.1 - 0.055 12.2 1.9 4.8 5.8 0.2 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Uma2 PF05685.12 CEG49810.1 - 0.0067 16.0 0.2 0.088 12.3 0.1 2.1 1 1 1 2 2 2 2 Putative restriction endonuclease zf-C2H2_4 PF13894.6 CEG49810.1 - 0.007 17.1 0.2 0.016 16.0 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CEG49810.1 - 0.032 14.7 0.1 0.07 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type SF3b1 PF08920.10 CEG49811.1 - 7.5e-37 126.4 20.6 2.3e-36 124.9 0.7 4.2 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CEG49811.1 - 4.3e-09 36.6 2.8 0.14 12.6 0.0 6.6 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 CEG49811.1 - 4.5e-08 32.7 6.9 4.1 7.9 0.0 9.0 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 CEG49811.1 - 1.8e-07 31.5 2.6 0.53 10.8 0.0 7.0 7 1 1 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.20 CEG49811.1 - 3.6e-05 22.5 2.9 0.035 12.7 0.0 3.1 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CEG49811.1 - 0.00066 20.2 0.8 30 5.3 0.0 5.0 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region UME PF08064.13 CEG49811.1 - 0.0045 16.9 1.7 16 5.5 0.0 5.6 6 2 1 8 8 8 0 UME (NUC010) domain Arm PF00514.23 CEG49811.1 - 0.039 14.0 0.0 36 4.6 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 CEG49811.1 - 0.042 13.5 0.4 2.9 7.5 0.0 4.0 4 2 1 5 5 5 0 NUC173 domain ParcG PF10274.9 CEG49811.1 - 0.057 13.5 0.8 6 7.0 0.0 3.9 2 2 4 6 6 6 0 Parkin co-regulated protein TIP120 PF08623.10 CEG49811.1 - 0.13 12.1 0.7 1.2 8.8 0.0 2.9 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 CEG49811.1 - 0.13 11.8 0.3 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal PMM PF03332.13 CEG49813.1 - 1.6e-103 345.3 2.2 1.9e-103 345.0 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CEG49813.1 - 2.7e-05 24.1 0.3 6.1e-05 22.9 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CEG49813.1 - 0.0028 17.2 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Slu7 PF11708.8 CEG49814.1 - 5.3e-98 328.0 17.3 5.3e-98 328.0 17.3 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Glyco_hydro_6 PF01341.17 CEG49815.1 - 0.01 15.6 0.3 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 LPP PF04728.13 CEG49816.1 - 0.014 15.8 1.1 0.014 15.8 1.1 3.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 CEG49816.1 - 0.019 15.0 7.4 0.019 15.0 7.4 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Metal_resist PF13801.6 CEG49816.1 - 0.63 10.2 6.3 1 9.6 6.3 1.3 1 0 0 1 1 1 0 Heavy-metal resistance HIP1_clath_bdg PF16515.5 CEG49816.1 - 0.94 10.1 32.1 4.3 8.0 17.0 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 CEG49816.1 - 3.1 5.6 18.2 3.3 5.5 18.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CEG49816.1 - 3.5 7.7 20.1 1.9 8.5 8.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 CEG49816.1 - 6.1 7.0 10.3 10 6.3 7.1 2.5 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal BRE1 PF08647.11 CEG49816.1 - 9.3 6.4 32.9 3.8 7.7 23.5 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase H_PPase PF03030.16 CEG49818.1 - 1.1e-205 685.1 27.2 4.9e-105 352.6 8.8 3.0 1 1 2 3 3 3 3 Inorganic H+ pyrophosphatase GtrA PF04138.14 CEG49818.1 - 1.4 9.2 13.3 0.12 12.6 2.1 3.3 2 0 0 2 2 2 0 GtrA-like protein DUF4231 PF14015.6 CEG49818.1 - 2.8 8.4 6.2 0.9 10.0 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Citrate_synt PF00285.21 CEG49819.1 - 0.079 12.0 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Kelch_4 PF13418.6 CEG49822.1 - 8.2e-31 105.8 21.9 1.3e-08 34.7 0.2 9.0 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CEG49822.1 - 3.4e-28 97.1 20.8 2.9e-07 30.3 0.8 7.8 7 1 0 7 7 7 6 Kelch motif TPR_2 PF07719.17 CEG49822.1 - 1.8e-22 77.6 15.9 0.023 14.8 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 CEG49822.1 - 3.8e-21 74.0 20.8 0.00017 21.2 0.0 9.7 11 0 0 11 11 8 5 Tetratricopeptide repeat Kelch_1 PF01344.25 CEG49822.1 - 1.4e-20 72.6 24.2 7.9e-08 31.8 1.4 7.4 7 2 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 CEG49822.1 - 1.4e-19 69.3 19.4 3e-05 23.8 1.8 7.8 6 2 0 6 6 6 4 Kelch motif TPR_19 PF14559.6 CEG49822.1 - 2e-18 66.6 5.3 0.0003 21.2 0.1 7.4 5 3 0 6 6 6 3 Tetratricopeptide repeat Kelch_6 PF13964.6 CEG49822.1 - 1.1e-17 63.7 23.9 0.014 15.6 0.1 8.6 9 0 0 9 9 8 5 Kelch motif TPR_12 PF13424.6 CEG49822.1 - 2.9e-17 62.7 7.8 6.8e-05 23.1 0.0 7.8 6 3 1 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49822.1 - 3.1e-17 62.0 1.2 0.22 12.2 0.0 10.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49822.1 - 2.2e-16 58.6 6.9 0.007 16.3 0.0 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat Kelch_3 PF13415.6 CEG49822.1 - 2.5e-16 59.5 30.6 7.4e-06 26.1 1.4 8.9 9 2 0 9 9 7 3 Galactose oxidase, central domain ANAPC3 PF12895.7 CEG49822.1 - 2.3e-13 50.2 14.0 0.0026 17.9 0.3 7.5 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEG49822.1 - 2.4e-12 46.0 14.3 0.12 12.7 0.0 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49822.1 - 4.6e-12 46.4 0.5 0.14 12.9 0.2 7.0 4 3 5 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49822.1 - 4.7e-12 45.6 0.9 2.3 9.3 0.0 7.8 7 2 2 9 9 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49822.1 - 7.4e-11 41.6 7.1 0.013 15.2 0.0 7.4 7 0 0 7 7 7 2 TPR repeat TPR_9 PF13371.6 CEG49822.1 - 6.1e-06 26.3 0.0 3.5 7.8 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEG49822.1 - 0.00024 21.3 6.0 2.5 8.7 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG49822.1 - 0.00031 20.2 6.8 0.83 9.0 0.1 5.0 5 1 1 6 6 5 2 MalT-like TPR region DUF2225 PF09986.9 CEG49822.1 - 0.00043 20.1 5.0 0.0017 18.1 0.2 3.5 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.9 CEG49822.1 - 0.0014 18.4 6.7 0.0055 16.4 0.4 3.0 3 1 0 3 3 2 1 Tetratricopeptide repeat-like domain MIT PF04212.18 CEG49822.1 - 0.0051 16.8 2.3 8.8 6.5 0.1 4.6 4 1 1 5 5 3 0 MIT (microtubule interacting and transport) domain DUF3808 PF10300.9 CEG49822.1 - 0.0084 14.9 0.3 0.46 9.2 0.0 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3808) DUF4810 PF16068.5 CEG49822.1 - 0.037 14.6 0.3 1.9 9.1 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.6 CEG49822.1 - 0.092 12.8 0.9 36 4.5 0.0 4.9 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CEG49822.1 - 0.14 12.5 2.3 17 5.8 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Glyco_tran_28_C PF04101.16 CEG49822.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TPR_10 PF13374.6 CEG49822.1 - 0.31 11.0 15.7 6.1 6.9 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat RVT_2 PF07727.14 CEG49827.1 - 0.038 13.6 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AT_hook PF02178.19 CEG49828.1 - 0.32 11.0 5.3 0.67 10.0 5.3 1.6 1 0 0 1 1 1 0 AT hook motif Herpeto_peptide PF14409.6 CEG49829.1 - 0.12 12.6 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon ABC_tran PF00005.27 CEG49835.1 - 9e-41 139.6 0.0 2.6e-20 73.3 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEG49835.1 - 3.1e-17 63.3 0.0 2.5e-05 24.3 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEG49835.1 - 2e-11 43.8 0.5 0.005 16.3 0.0 4.7 5 0 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEG49835.1 - 7.2e-07 29.6 0.0 0.026 14.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEG49835.1 - 4.8e-06 26.6 1.7 0.038 13.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 CEG49835.1 - 5.5e-06 26.4 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 CEG49835.1 - 1.8e-05 23.9 1.2 0.013 14.5 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CEG49835.1 - 1.8e-05 24.8 0.0 0.056 13.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CEG49835.1 - 5.2e-05 22.9 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CEG49835.1 - 5.3e-05 23.5 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 CEG49835.1 - 9.1e-05 22.7 0.0 0.61 10.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 CEG49835.1 - 0.00013 21.6 0.3 0.14 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain CLASP_N PF12348.8 CEG49835.1 - 0.00018 21.1 1.4 0.0049 16.5 0.1 2.5 1 1 1 2 2 2 1 CLASP N terminal AAA_33 PF13671.6 CEG49835.1 - 0.0002 21.5 0.1 0.32 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG49835.1 - 0.00022 21.6 0.1 0.92 9.9 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEG49835.1 - 0.00024 20.9 0.0 0.63 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG49835.1 - 0.00029 21.2 7.7 0.38 11.1 0.0 4.2 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 CEG49835.1 - 0.00042 20.9 0.0 1.8 9.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CEG49835.1 - 0.00063 19.9 1.4 0.045 13.8 0.0 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_14 PF13173.6 CEG49835.1 - 0.0012 18.8 0.0 1.9 8.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEG49835.1 - 0.0023 17.1 0.1 2.5 7.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 CEG49835.1 - 0.0037 16.5 0.1 0.27 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CEG49835.1 - 0.0043 17.4 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CEG49835.1 - 0.0043 16.8 2.5 3.4 7.4 0.0 3.9 4 1 0 4 4 4 1 AAA domain AAA_23 PF13476.6 CEG49835.1 - 0.0051 17.3 2.4 2 8.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 CEG49835.1 - 0.01 15.8 0.2 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 CEG49835.1 - 0.013 15.1 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CEG49835.1 - 0.024 14.4 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CEG49835.1 - 0.029 13.9 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4638 PF15472.6 CEG49835.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Arf PF00025.21 CEG49835.1 - 0.034 13.6 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 CEG49835.1 - 0.036 13.8 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RE_HindVP PF09519.10 CEG49835.1 - 0.052 12.6 0.8 0.11 11.5 0.8 1.5 1 0 0 1 1 1 0 HindVP restriction endonuclease AAA_17 PF13207.6 CEG49835.1 - 0.083 13.3 1.6 9.7 6.6 0.1 3.1 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 CEG49835.1 - 0.085 12.1 0.0 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 CEG49835.1 - 0.096 12.7 0.6 0.44 10.6 0.0 2.4 3 0 0 3 3 2 0 Dynamin family MobB PF03205.14 CEG49835.1 - 0.097 12.6 0.2 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 CEG49835.1 - 0.1 12.2 0.9 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 CEG49835.1 - 0.11 12.2 0.5 12 5.5 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase SRP54 PF00448.22 CEG49835.1 - 0.11 12.1 1.2 9.7 5.8 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 CEG49835.1 - 0.11 12.2 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Vac14_Fab1_bd PF12755.7 CEG49835.1 - 0.13 12.9 0.2 21 5.8 0.0 3.6 4 0 0 4 4 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEG49835.1 - 0.19 12.3 9.4 6.6 7.3 0.2 5.3 5 1 1 6 6 3 0 HEAT-like repeat ATP_bind_1 PF03029.17 CEG49835.1 - 0.22 11.3 1.2 14 5.4 0.1 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein UME PF08064.13 CEG49835.1 - 0.38 10.7 5.3 0.4 10.6 0.2 3.3 3 1 1 4 4 3 0 UME (NUC010) domain DUF3584 PF12128.8 CEG49835.1 - 1.9 5.9 7.9 4.5 4.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF1765 PF08578.10 CEG49836.1 - 2.9e-06 27.7 5.8 8.2e-06 26.3 5.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Bin3 PF06859.12 CEG49837.1 - 4.6e-38 130.2 0.8 1.8e-37 128.3 0.0 2.2 3 0 0 3 3 3 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 CEG49837.1 - 3.2e-14 53.5 0.0 2e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEG49837.1 - 2.3e-12 47.1 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG49837.1 - 1.2e-10 41.3 0.0 6.4e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CEG49837.1 - 3.7e-10 40.4 0.0 4.1e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CEG49837.1 - 3.1e-08 34.2 0.0 0.0066 17.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.7 CEG49837.1 - 8.8e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEG49837.1 - 0.00012 21.5 0.2 0.00074 19.0 0.0 2.2 2 1 1 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CEG49837.1 - 0.0011 18.5 0.0 0.0092 15.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.18 CEG49837.1 - 0.0039 16.7 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain NodS PF05401.11 CEG49837.1 - 0.024 14.2 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) MTS PF05175.14 CEG49837.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 CEG49837.1 - 0.047 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CEG49837.1 - 0.1 11.9 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_S9 PF00380.19 CEG49838.1 - 1.7e-20 73.8 1.6 1.8e-20 73.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 LSM PF01423.22 CEG49838.1 - 1.1e-13 50.6 1.0 2.3e-13 49.6 0.5 1.8 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 CEG49838.1 - 0.00018 21.6 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain UPF0113_N PF17833.1 CEG49839.1 - 4.9e-27 94.3 0.1 7.7e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CEG49839.1 - 2.8e-23 81.9 0.0 4.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain Mito_carr PF00153.27 CEG49840.1 - 8.4e-66 218.0 5.6 4.3e-22 77.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Retrotran_gag_2 PF14223.6 CEG49844.1 - 9.4e-12 44.8 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CEG49844.1 - 2.7e-05 24.0 2.7 4.8e-05 23.2 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle CKAP2_C PF15297.6 CEG49844.1 - 0.078 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus zf-CCHC_5 PF14787.6 CEG49844.1 - 0.15 11.8 2.4 0.27 11.0 2.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MR_MLE_C PF13378.6 CEG49846.1 - 0.082 12.5 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Enolase C-terminal domain-like HEAT PF02985.22 CEG49847.1 - 2.1e-31 105.3 36.9 0.0007 19.6 0.0 20.7 23 0 0 23 23 22 7 HEAT repeat HEAT_EZ PF13513.6 CEG49847.1 - 9.6e-25 86.7 49.9 8.7e-05 22.9 0.0 19.8 16 3 4 20 20 20 5 HEAT-like repeat HEAT_2 PF13646.6 CEG49847.1 - 1.2e-23 83.3 47.8 0.0014 19.0 0.0 18.5 12 3 10 22 22 22 8 HEAT repeats Cnd1 PF12717.7 CEG49847.1 - 1.1e-17 64.6 12.3 0.11 12.6 0.0 11.9 8 3 4 12 12 12 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEG49847.1 - 2.6e-12 47.2 1.0 0.76 10.4 0.1 9.4 10 0 0 10 10 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEG49847.1 - 5.4e-10 39.2 14.2 0.00073 19.2 0.0 10.0 10 2 2 12 12 12 1 CLASP N terminal Adaptin_N PF01602.20 CEG49847.1 - 6.9e-08 31.5 21.7 0.00078 18.1 0.8 8.2 8 1 0 8 8 8 3 Adaptin N terminal region Dopey_N PF04118.14 CEG49847.1 - 0.00024 20.3 0.1 0.64 9.1 0.0 4.0 3 0 0 3 3 3 2 Dopey, N-terminal ParcG PF10274.9 CEG49847.1 - 0.00082 19.5 4.7 6.4 6.8 0.0 6.5 6 1 1 7 7 7 1 Parkin co-regulated protein Cohesin_HEAT PF12765.7 CEG49847.1 - 0.0012 19.1 11.8 0.058 13.7 0.0 6.9 8 0 0 8 8 7 1 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 CEG49847.1 - 0.0022 18.1 2.8 2.9 8.1 0.1 5.5 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 NUC173 PF08161.12 CEG49847.1 - 0.0058 16.3 0.3 31 4.1 0.0 5.4 5 0 0 5 5 5 0 NUC173 domain UME PF08064.13 CEG49847.1 - 0.029 14.3 6.1 9.4 6.2 0.0 6.8 7 1 1 8 8 8 0 UME (NUC010) domain Tcf25 PF04910.14 CEG49847.1 - 0.086 11.9 0.5 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 IPP-2 PF04979.14 CEG49847.1 - 0.11 13.3 2.2 0.23 12.2 2.2 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) FANCI_S3 PF14677.6 CEG49847.1 - 0.13 12.0 2.1 51 3.5 0.0 4.5 4 0 0 4 4 4 0 FANCI solenoid 3 MMS22L_C PF14911.6 CEG49847.1 - 1.3 8.0 5.7 0.78 8.8 0.1 3.2 4 0 0 4 4 4 0 S-phase genomic integrity recombination mediator, C-terminal SF1-HH PF16275.5 CEG49848.1 - 1.4e-31 109.2 0.8 3.6e-31 107.8 0.8 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CEG49848.1 - 1.6e-08 34.2 0.6 3.5e-08 33.2 0.6 1.6 1 0 0 1 1 1 1 KH domain PHD_4 PF16866.5 CEG49848.1 - 0.00011 22.3 4.2 0.00028 20.9 4.2 1.7 1 0 0 1 1 1 1 PHD-finger Cytidylate_kin2 PF13189.6 CEG49848.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase-like family zf-CCHC PF00098.23 CEG49848.1 - 0.073 13.2 11.8 0.055 13.6 4.9 2.7 2 0 0 2 2 2 0 Zinc knuckle PolC_DP2 PF03833.13 CEG49848.1 - 0.11 10.3 3.1 0.16 9.8 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_2 PF13696.6 CEG49848.1 - 0.38 10.6 11.3 0.068 13.0 6.9 2.0 2 0 0 2 2 2 0 Zinc knuckle Smg4_UPF3 PF03467.15 CEG49848.1 - 0.53 10.3 3.6 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Smg-4/UPF3 family SlyX PF04102.12 CEG49848.1 - 0.55 10.9 3.5 0.25 12.0 0.3 2.1 2 0 0 2 2 2 0 SlyX zf-CCHC_3 PF13917.6 CEG49848.1 - 0.92 9.5 8.4 0.45 10.5 1.8 2.7 1 1 1 2 2 2 0 Zinc knuckle Pkinase PF00069.25 CEG49849.1 - 4.7e-14 52.4 0.0 8.3e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG49849.1 - 4.7e-06 26.1 0.0 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEG49849.1 - 0.05 12.6 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FSH1 PF03959.13 CEG49850.1 - 1.7e-25 89.9 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) START PF01852.19 CEG49851.1 - 4.2e-24 85.1 0.0 5.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 START domain zf-XS PF03470.14 CEG49851.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 XS zinc finger domain Motile_Sperm PF00635.26 CEG49852.1 - 1.3e-19 70.0 0.6 3e-08 33.5 0.0 3.3 3 0 0 3 3 3 2 MSP (Major sperm protein) domain TM231 PF10149.9 CEG49853.1 - 5.4e-52 177.0 9.8 6e-52 176.9 9.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 Pex19 PF04614.12 CEG49854.1 - 1.4e-33 116.7 30.8 1.5e-32 113.3 30.8 2.0 1 1 0 1 1 1 1 Pex19 protein family SMI1_KNR4 PF09346.10 CEG49854.1 - 0.023 15.1 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) CNDH2_C PF16858.5 CEG49854.1 - 0.098 12.5 10.2 0.15 11.9 10.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Spectrin PF00435.21 CEG49854.1 - 0.099 13.1 0.1 0.099 13.1 0.1 3.0 1 1 4 5 5 5 0 Spectrin repeat SesA PF17107.5 CEG49854.1 - 0.16 12.2 5.2 4 7.7 0.6 2.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF445 PF04286.12 CEG49854.1 - 0.19 11.5 8.4 5.4 6.7 7.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2791 PF10923.8 CEG49854.1 - 0.39 9.5 6.0 0.33 9.7 2.6 2.0 1 1 1 2 2 2 0 P-loop Domain of unknown function (DUF2791) SRP54_N PF02881.19 CEG49854.1 - 0.47 10.7 0.0 0.47 10.7 0.0 3.1 3 1 0 3 3 3 0 SRP54-type protein, helical bundle domain FdhE PF04216.12 CEG49854.1 - 0.58 10.0 4.2 0.43 10.4 2.4 1.7 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Spore_III_AB PF09548.10 CEG49854.1 - 5 7.2 6.9 1.6 8.8 2.4 2.3 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Occludin_ELL PF07303.13 CEG49854.1 - 5.7 7.7 9.9 9.4 7.0 0.6 3.6 2 1 2 4 4 4 0 Occludin homology domain BRCT PF00533.26 CEG49855.1 - 2.6e-06 27.7 0.1 0.0023 18.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEG49855.1 - 0.00014 22.2 0.1 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CEG49855.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEG49855.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 twin BRCT domain NST1 PF13945.6 CEG49859.1 - 0.059 13.5 0.7 0.071 13.2 0.7 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator AMP-binding PF00501.28 CEG49860.1 - 4.5e-70 236.4 0.0 5.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEG49860.1 - 0.00043 21.2 0.0 0.0009 20.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mcp5_PH PF12814.7 CEG49861.1 - 0.039 14.1 0.2 0.16 12.1 0.2 2.2 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Abhydrolase_3 PF07859.13 CEG49862.1 - 7.8e-31 107.6 0.0 9.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEG49862.1 - 9.8e-09 34.5 0.0 1.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEG49862.1 - 0.00022 20.8 0.0 0.00034 20.1 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1997 PF09366.10 CEG49862.1 - 0.053 13.7 0.0 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) mRNA_stabil PF13929.6 CEG49865.1 - 0.036 13.0 0.5 0.056 12.4 0.5 1.2 1 0 0 1 1 1 0 mRNA stabilisation DUF2345 PF10106.9 CEG49865.1 - 0.057 13.3 0.6 0.12 12.3 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) AT_hook PF02178.19 CEG49865.1 - 0.078 12.9 3.9 0.18 11.8 3.9 1.6 1 0 0 1 1 1 0 AT hook motif Tenui_NCP PF04876.12 CEG49865.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Pox_RNA_Pol_19 PF05320.12 CEG49866.1 - 0.039 13.9 0.2 0.044 13.8 0.2 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Cu-oxidase_2 PF07731.14 CEG49870.1 - 2e-29 102.1 0.6 3.3e-29 101.3 0.6 1.3 1 1 0 1 1 1 1 Multicopper oxidase Glyco_hydro_1 PF00232.18 CEG49873.1 - 8.4e-167 555.2 0.1 9.7e-167 555.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DA1-like PF12315.8 CEG49876.1 - 4.8e-42 143.7 0.2 1.3e-41 142.2 0.2 1.7 1 1 0 1 1 1 1 Protein DA1 LIM PF00412.22 CEG49876.1 - 2.6e-17 62.8 12.9 3.5e-11 43.1 3.3 5.4 2 2 2 4 4 4 2 LIM domain KASH_CCD PF14662.6 CEG49877.1 - 6.2e-05 22.9 32.0 6.2e-05 22.9 32.0 4.2 2 2 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 CEG49877.1 - 0.38 10.6 10.3 0.037 13.9 3.2 3.1 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vip3A_N PF12495.8 CEG49877.1 - 0.65 9.9 4.4 0.44 10.4 0.8 2.3 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal Filament PF00038.21 CEG49877.1 - 9.5 5.7 55.1 2 7.9 9.4 4.2 1 1 2 3 3 3 0 Intermediate filament protein HSBP1 PF06825.12 CEG49878.1 - 2.2e-17 62.7 1.7 2.7e-17 62.3 1.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 YvrJ PF12841.7 CEG49878.1 - 0.23 11.0 0.1 0.5 9.9 0.0 1.6 2 0 0 2 2 2 0 YvrJ protein family HSP70 PF00012.20 CEG49879.1 - 4.9e-266 883.7 12.1 5.6e-266 883.5 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEG49879.1 - 8.2e-16 57.7 0.6 7.7e-13 48.0 0.1 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CEG49879.1 - 0.0038 17.6 3.2 3.6 8.1 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 CEG49879.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4192 PF13830.6 CEG49879.1 - 0.79 9.7 3.4 1.6 8.7 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Rho_RNA_bind PF07497.12 CEG49880.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain zf-C3HC PF07967.13 CEG49881.1 - 6.1e-32 110.4 0.1 1.1e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 CEG49881.1 - 1.1e-07 31.9 6.1 1.9e-05 24.7 0.3 2.9 2 1 0 2 2 2 2 Rsm1-like OSCP PF00213.18 CEG49881.1 - 0.043 14.0 0.4 0.42 10.7 0.3 2.1 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit KASH_CCD PF14662.6 CEG49882.1 - 0.00011 22.0 1.0 0.00013 21.8 1.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spectrin PF00435.21 CEG49882.1 - 0.0005 20.5 0.7 0.28 11.7 1.4 2.3 2 1 0 2 2 2 1 Spectrin repeat RRM_1 PF00076.22 CEG49882.1 - 0.004 16.9 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS2_interact PF15784.5 CEG49882.1 - 0.013 15.9 1.5 0.025 15.0 1.5 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain YabA PF06156.13 CEG49882.1 - 0.016 15.8 0.2 0.023 15.3 0.2 1.3 1 1 0 1 1 1 0 Initiation control protein YabA p25-alpha PF05517.12 CEG49882.1 - 0.035 14.3 0.4 0.046 13.9 0.4 1.2 1 0 0 1 1 1 0 p25-alpha Apolipoprotein PF01442.18 CEG49882.1 - 0.039 13.8 5.5 0.09 12.6 5.6 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain XhlA PF10779.9 CEG49882.1 - 0.089 13.0 0.7 0.19 12.0 0.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Rho_Binding PF08912.11 CEG49882.1 - 0.13 13.1 4.0 0.24 12.2 4.0 1.5 1 0 0 1 1 1 0 Rho Binding COG2 PF06148.11 CEG49882.1 - 0.14 12.2 1.3 0.2 11.7 1.3 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 CEG49882.1 - 0.17 12.2 3.4 0.34 11.2 1.2 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5407 PF17401.2 CEG49882.1 - 0.66 10.3 4.7 1.5 9.1 4.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5407) SANT_DAMP1_like PF16282.5 CEG49883.1 - 1.3e-25 89.4 1.8 2.7e-25 88.4 1.8 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 CEG49883.1 - 1.7e-14 54.0 4.0 4.2e-14 52.8 4.0 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 CEG49883.1 - 0.0019 18.3 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aa_trans PF01490.18 CEG49884.1 - 2.9e-69 233.8 33.1 3.3e-69 233.6 33.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEG49884.1 - 1.1e-14 54.3 33.6 1.4e-13 50.7 33.6 2.1 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family FYVE PF01363.21 CEG49885.1 - 1.6e-12 47.4 5.9 5.1e-12 45.8 5.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG49885.1 - 0.0029 17.8 3.6 0.0099 16.1 3.6 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 CEG49885.1 - 1.3 9.2 5.8 4.1 7.6 5.8 1.9 1 0 0 1 1 1 0 Piccolo Zn-finger ABC_tran_Xtn PF12848.7 CEG49887.1 - 1.6 8.8 6.4 7.5 6.7 6.4 2.2 1 0 0 1 1 1 0 ABC transporter UPF0242 PF06785.11 CEG49887.1 - 3.2 7.8 11.3 0.49 10.5 4.6 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 CEG49887.1 - 5 7.5 11.0 0.27 11.5 4.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) 2-oxoacid_dh PF00198.23 CEG49888.1 - 1.8e-62 210.8 0.3 2.9e-62 210.1 0.3 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEG49888.1 - 1e-32 111.8 12.9 3.3e-16 58.9 5.3 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEG49888.1 - 0.00012 21.9 0.9 0.00012 21.9 0.9 3.6 2 2 2 4 4 4 1 Biotin-lipoyl like HlyD_3 PF13437.6 CEG49888.1 - 0.00066 20.4 9.8 0.07 13.8 0.1 4.1 2 2 2 4 4 4 2 HlyD family secretion protein RnfC_N PF13375.6 CEG49888.1 - 0.064 13.2 3.5 0.44 10.5 1.2 3.1 2 2 1 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CEG49888.1 - 0.066 13.1 6.2 0.79 9.6 1.4 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF1126 PF06565.12 CEG49890.1 - 4.4e-81 267.5 4.9 2.1e-26 91.8 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain Ins134_P3_kin PF05770.11 CEG49891.1 - 2e-35 122.1 0.1 3.3e-35 121.4 0.1 1.3 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 CEG49891.1 - 0.0034 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Retrotran_gag_2 PF14223.6 CEG49892.1 - 5.9e-14 51.9 0.9 7.7e-14 51.5 0.9 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NADH-UOR_E PF16514.5 CEG49892.1 - 0.37 11.1 2.1 2.3 8.6 2.0 2.1 1 1 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E PIN_6 PF17146.4 CEG49893.1 - 0.051 14.1 0.3 0.076 13.5 0.3 1.4 1 1 0 1 1 1 0 PIN domain of ribonuclease Endotoxin_N PF03945.14 CEG49894.1 - 0.19 11.4 0.2 1.4 8.6 0.1 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DIMCO_N PF16844.5 CEG49898.1 - 0.055 13.8 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal ALS_ss_C PF10369.9 CEG49901.1 - 0.026 14.7 0.4 0.081 13.2 0.2 1.9 2 0 0 2 2 2 0 Small subunit of acetolactate synthase CENP-F_leu_zip PF10473.9 CEG49901.1 - 0.11 12.5 13.7 0.23 11.5 13.7 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 CEG49901.1 - 0.19 10.2 3.1 0.23 10.0 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF313 PF03754.13 CEG49901.1 - 0.37 11.0 4.5 2.5 8.3 4.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF313) FapA PF03961.13 CEG49901.1 - 0.51 8.9 9.1 0.65 8.5 9.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 CEG49901.1 - 0.58 10.8 12.4 1.8 9.2 8.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 CEG49901.1 - 0.71 10.1 14.2 8.9 6.6 14.2 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding E2R135 PF11570.8 CEG49901.1 - 0.95 9.8 8.1 0.73 10.1 1.2 2.4 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 GvpK PF05121.12 CEG49901.1 - 1.2 9.3 6.3 1.7 8.7 1.5 2.9 2 1 1 3 3 3 0 Gas vesicle protein K DUF2968 PF11180.8 CEG49901.1 - 1.2 8.7 13.4 0.6 9.7 11.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Rab_bind PF16704.5 CEG49901.1 - 2.2 8.4 7.7 2 8.5 3.5 2.5 1 1 0 2 2 2 0 Rab binding domain Spc7 PF08317.11 CEG49901.1 - 3.1 6.6 17.6 2.4 7.0 15.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein WXG100 PF06013.12 CEG49901.1 - 3.9 7.8 8.1 28 5.0 6.2 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG APG6_N PF17675.1 CEG49901.1 - 4 8.0 17.3 1.3 9.6 13.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2730 PF10805.8 CEG49901.1 - 9.9 6.3 10.2 22 5.2 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Arrestin_C PF02752.22 CEG49902.1 - 1.7e-10 41.5 0.1 4.5e-09 36.8 0.0 2.9 4 0 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEG49902.1 - 1.4e-06 28.4 0.1 4e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain E1_DerP2_DerF2 PF02221.15 CEG49902.1 - 0.0052 17.2 0.3 0.021 15.3 0.2 2.1 2 1 0 2 2 2 1 ML domain NOA36 PF06524.12 CEG49902.1 - 0.024 14.0 1.1 0.035 13.4 1.1 1.2 1 0 0 1 1 1 0 NOA36 protein IQ PF00612.27 CEG49906.1 - 2.1e-22 76.7 30.6 0.0028 17.3 1.2 8.0 7 0 0 7 7 7 7 IQ calmodulin-binding motif DUF948 PF06103.11 CEG49909.1 - 0.0099 16.1 0.2 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) zf-B_box PF00643.24 CEG49909.1 - 3.7 7.8 17.2 0.16 12.2 8.0 2.8 2 0 0 2 2 2 0 B-box zinc finger Histone_H2A_C PF16211.5 CEG49910.1 - 5.1e-20 70.9 0.7 5.1e-20 70.9 0.7 1.9 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CEG49910.1 - 2.8e-15 56.8 0.0 3.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEG49910.1 - 0.00052 20.3 0.0 0.0008 19.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_hydro_19 PF00182.19 CEG49911.1 - 4.8e-48 164.1 1.8 1.2e-46 159.5 1.8 2.2 1 1 0 1 1 1 1 Chitinase class I Ins_allergen_rp PF06757.13 CEG49911.1 - 0.16 11.9 0.3 0.33 10.9 0.2 1.6 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Glyco_hydro_19 PF00182.19 CEG49913.1 - 8.7e-46 156.7 5.9 1.8e-44 152.3 5.9 2.2 1 1 0 1 1 1 1 Chitinase class I pPIWI_RE_Z PF18155.1 CEG49914.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Glyco_hydro_28 PF00295.17 CEG49916.1 - 6.2e-68 229.2 11.8 7.6e-68 228.9 11.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CEG49916.1 - 1.5e-07 31.4 23.2 3.5e-07 30.2 17.8 2.9 2 1 1 3 3 3 1 Right handed beta helix region NosD PF05048.13 CEG49916.1 - 0.00042 19.6 7.3 0.00042 19.6 7.3 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) CAP_GLY PF01302.25 CEG49916.1 - 0.043 13.8 0.2 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 CAP-Gly domain SMC_N PF02463.19 CEG49917.1 - 3.2e-65 219.6 36.7 1.3e-64 217.6 36.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEG49917.1 - 6.5e-24 84.5 0.6 2.4e-23 82.7 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CEG49917.1 - 1.9e-14 54.2 5.9 4.8e-06 26.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEG49917.1 - 2.4e-09 37.4 22.1 2.4e-09 37.4 22.1 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CEG49917.1 - 2.3e-05 24.0 0.0 7.5e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CEG49917.1 - 7.4e-05 23.3 38.5 7.4e-05 23.3 38.5 6.8 2 2 2 4 4 4 1 AAA domain SbcCD_C PF13558.6 CEG49917.1 - 0.035 14.3 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CEG49917.1 - 0.063 13.8 0.0 0.063 13.8 0.0 6.2 4 3 0 4 4 4 0 ABC transporter ThiF PF00899.21 CEG49918.1 - 5.6e-61 206.0 0.1 8.6e-61 205.4 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CEG49918.1 - 1.7e-21 76.1 0.1 3.5e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 CEG49918.1 - 0.00022 21.8 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 CEG49918.1 - 0.04 14.0 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_41 PF13844.6 CEG49920.1 - 9.6e-140 466.1 0.4 4.2e-75 253.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 CEG49920.1 - 4e-92 298.6 45.1 9.9e-11 41.0 0.3 13.3 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49920.1 - 1.2e-83 274.6 39.1 6.7e-14 51.3 0.2 12.5 2 1 10 12 12 12 11 TPR repeat TPR_8 PF13181.6 CEG49920.1 - 1.9e-71 230.4 25.7 1.8e-06 27.7 0.0 12.2 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49920.1 - 2.2e-70 227.2 44.8 1.3e-07 31.2 0.2 12.7 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_17 PF13431.6 CEG49920.1 - 4.8e-53 173.8 31.8 5.4e-05 23.3 0.3 12.5 11 1 1 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49920.1 - 1.6e-52 171.7 17.6 2.3e-05 24.1 0.0 12.7 12 1 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49920.1 - 8.7e-45 150.9 37.2 3.8e-09 36.7 1.2 9.0 3 3 4 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49920.1 - 5.9e-42 142.0 20.6 5.7e-08 33.3 1.3 9.0 4 2 3 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49920.1 - 2.5e-39 130.6 20.5 0.00097 19.8 0.0 12.0 3 1 9 12 12 11 10 Tetratricopeptide repeat TPR_19 PF14559.6 CEG49920.1 - 5.2e-37 126.2 23.8 7e-07 29.7 0.1 9.2 3 1 7 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 CEG49920.1 - 7.7e-32 108.3 47.9 8.4e-05 22.3 0.3 12.4 10 2 2 12 12 12 7 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49920.1 - 1.5e-21 75.5 18.2 0.15 12.8 0.0 10.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_9 PF13371.6 CEG49920.1 - 1.2e-14 54.2 10.7 0.14 12.3 0.0 7.4 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_MalT PF17874.1 CEG49920.1 - 5.9e-13 48.9 7.5 0.0017 17.8 1.0 5.2 1 1 2 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 CEG49920.1 - 3.7e-11 42.5 0.7 13 6.7 0.0 9.3 11 0 0 11 11 8 0 Tetratricopeptide repeat NARP1 PF12569.8 CEG49920.1 - 5.1e-10 38.9 1.8 0.46 9.3 0.1 5.5 1 1 4 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CEG49920.1 - 2.4e-09 36.8 5.7 0.024 13.8 0.5 5.8 1 1 1 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 CEG49920.1 - 6.7e-09 35.4 13.5 0.27 11.6 0.0 8.3 8 0 0 8 8 8 2 PPR repeat FAT PF02259.23 CEG49920.1 - 1.3e-08 34.5 0.6 0.091 12.0 0.2 5.4 1 1 3 4 4 4 2 FAT domain BTAD PF03704.17 CEG49920.1 - 2.4e-08 34.6 21.1 0.015 15.8 0.0 6.3 3 1 3 6 6 6 3 Bacterial transcriptional activator domain TPR_21 PF09976.9 CEG49920.1 - 4.9e-08 32.9 7.2 0.032 14.0 0.8 4.6 1 1 3 4 4 4 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CEG49920.1 - 2e-05 24.8 24.8 0.022 15.0 1.0 6.7 2 2 6 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CEG49920.1 - 2e-05 23.9 1.2 2.1 7.8 0.0 5.3 5 1 1 6 6 5 2 SHNi-TPR EST1_DNA_bind PF10373.9 CEG49920.1 - 2.6e-05 23.8 19.0 0.08 12.4 0.4 5.4 4 2 1 5 5 5 2 Est1 DNA/RNA binding domain RPN7 PF10602.9 CEG49920.1 - 3.8e-05 23.5 7.6 0.95 9.1 0.0 6.2 3 3 4 7 7 7 2 26S proteasome subunit RPN7 SNAP PF14938.6 CEG49920.1 - 8.9e-05 22.0 17.5 0.026 14.0 1.3 4.5 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 CEG49920.1 - 0.00024 21.1 27.3 0.47 10.6 0.3 10.1 10 1 1 11 11 10 1 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 CEG49920.1 - 0.0032 16.9 0.2 3.7 6.9 0.0 3.6 3 1 0 3 3 3 1 Coatomer epsilon subunit DUF5113 PF17140.4 CEG49920.1 - 0.0037 17.1 13.8 6.6 6.5 0.1 6.2 3 1 4 7 7 7 0 Domain of unknown function (DUF5113) DUF4071 PF13281.6 CEG49920.1 - 0.014 14.5 0.1 0.056 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) EF-hand_3 PF09069.11 CEG49920.1 - 0.015 15.7 0.4 10 6.6 0.1 3.3 2 0 0 2 2 2 0 EF-hand TPR_20 PF14561.6 CEG49920.1 - 0.021 15.2 5.2 50 4.3 0.0 5.7 2 1 6 8 8 7 0 Tetratricopeptide repeat TOM20_plant PF06552.12 CEG49920.1 - 0.022 14.5 0.4 2.4 7.9 0.0 3.8 3 1 2 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4326 PF14216.6 CEG49920.1 - 0.64 10.8 3.3 1.6e+02 3.1 0.2 4.5 4 1 1 5 5 4 0 Domain of unknown function (DUF4326) TPR_3 PF07720.12 CEG49920.1 - 0.91 9.6 16.9 0.79 9.8 0.2 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CEG49920.1 - 0.92 9.6 7.5 3.4 7.8 0.1 4.5 3 2 0 4 4 4 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 CEG49920.1 - 2.3 8.3 8.2 8.9 6.4 0.2 5.2 4 2 1 6 6 5 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CEG49920.1 - 6.1 7.0 12.8 12 6.0 0.9 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_S24 PF00717.23 CEG49921.1 - 1.6e-09 37.6 0.1 3.3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like DUF2190 PF09956.9 CEG49921.1 - 0.053 14.0 0.0 13 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) PseudoU_synth_2 PF00849.22 CEG49922.1 - 9.2e-15 55.1 0.2 7.9e-14 52.0 0.1 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CEG49922.1 - 1e-08 34.8 0.4 2.7e-08 33.4 0.4 1.8 1 0 0 1 1 1 1 S4 domain Inhibitor_I48 PF10467.9 CEG49922.1 - 0.094 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin DDE_1 PF03184.19 CEG49924.1 - 5.5e-27 94.5 0.0 3e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CEG49924.1 - 1e-12 47.9 0.0 6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEG49924.1 - 9.7e-05 22.0 1.1 9.7e-05 22.0 1.1 2.7 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain RFC1 PF08519.12 CEG49925.1 - 0.0061 16.7 0.8 0.014 15.6 0.8 1.6 1 1 0 1 1 1 1 Replication factor RFC1 C terminal domain DUF3994 PF13159.6 CEG49925.1 - 0.029 14.9 0.3 0.65 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DcpS PF05652.12 CEG49926.1 - 0.028 15.2 1.1 6.3 7.7 0.1 2.1 1 1 1 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal BTG PF07742.12 CEG49927.1 - 0.022 14.6 0.4 0.063 13.1 0.4 1.7 1 0 0 1 1 1 0 BTG family KH_8 PF17903.1 CEG49927.1 - 0.16 12.0 5.1 5.7 7.1 0.3 4.5 2 1 4 6 6 6 0 Krr1 KH1 domain DUF4049 PF13258.6 CEG49928.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) MFS_1 PF07690.16 CEG49929.1 - 2.4e-29 102.4 38.2 2.4e-29 102.4 38.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG49929.1 - 2.4e-28 99.2 36.7 3.2e-28 98.8 36.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TMEM61 PF15105.6 CEG49929.1 - 0.15 11.9 0.8 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 TMEM61 protein family Trypsin PF00089.26 CEG49930.1 - 3.9e-28 98.8 0.5 4.9e-28 98.5 0.5 1.1 1 0 0 1 1 1 1 Trypsin DUF1336 PF07059.12 CEG49931.1 - 1.3e-61 208.6 0.0 1.2e-60 205.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 CEG49931.1 - 2.7e-15 56.4 0.2 4.9e-15 55.5 0.2 1.4 1 0 0 1 1 1 1 START domain PH PF00169.29 CEG49931.1 - 8.4e-07 29.5 0.2 6.6e-06 26.6 0.2 2.5 1 1 0 1 1 1 1 PH domain FANCI_HD1 PF14679.6 CEG49931.1 - 0.012 15.6 0.0 3.2 7.8 0.0 2.7 2 0 0 2 2 2 0 FANCI helical domain 1 ABC2_membrane PF01061.24 CEG49934.1 - 2.1e-68 229.9 73.2 1.7e-40 138.7 25.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEG49934.1 - 2.6e-37 128.4 0.0 3.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEG49934.1 - 3.1e-09 36.6 3.5 1.2e-07 31.6 0.0 3.5 2 1 0 2 2 2 1 CDR ABC transporter AAA_16 PF13191.6 CEG49934.1 - 2.1e-08 34.8 0.0 0.0013 19.2 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 CEG49934.1 - 1.1e-07 32.0 1.2 0.011 15.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEG49934.1 - 7.7e-07 29.2 2.1 0.012 15.5 0.3 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 CEG49934.1 - 1.9e-05 24.3 6.1 0.024 14.4 0.8 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG49934.1 - 3.2e-05 24.2 0.4 0.076 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 CEG49934.1 - 4.9e-05 22.6 58.7 0.0096 15.1 28.7 3.5 2 2 0 2 2 2 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 CEG49934.1 - 6.8e-05 22.2 1.3 0.006 15.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 CEG49934.1 - 6.9e-05 22.5 0.3 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CEG49934.1 - 0.00032 20.2 3.6 5.4 6.4 0.1 4.1 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEG49934.1 - 0.0013 19.2 1.5 0.18 12.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEG49934.1 - 0.002 17.9 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CEG49934.1 - 0.0023 17.9 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEG49934.1 - 0.0026 18.3 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEG49934.1 - 0.0056 17.1 0.4 11 6.4 0.1 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CEG49934.1 - 0.012 15.7 2.5 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_assoc PF08370.11 CEG49934.1 - 0.017 14.9 0.3 0.017 14.9 0.3 3.8 4 0 0 4 4 2 0 Plant PDR ABC transporter associated RNA_helicase PF00910.22 CEG49934.1 - 0.022 15.1 0.4 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CEG49934.1 - 0.025 14.8 1.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CEG49934.1 - 0.041 13.8 3.1 7.2 6.5 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 CEG49934.1 - 0.062 13.0 0.9 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 CEG49934.1 - 0.081 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 CEG49934.1 - 0.09 11.9 0.8 0.2 10.8 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 CEG49934.1 - 0.1 12.5 0.7 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 CEG49934.1 - 0.15 12.3 0.3 14 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEG49934.1 - 0.16 11.5 3.3 1.7 8.2 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CEG49934.1 - 0.23 11.5 6.8 1.4 8.9 0.1 2.9 4 0 0 4 4 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 CEG49934.1 - 0.42 10.4 2.3 5.4 6.8 0.5 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 CEG49934.1 - 0.63 8.8 2.7 2.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TsaE PF02367.17 CEG49934.1 - 0.76 9.8 2.8 1.8 8.6 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEG49934.1 - 0.87 9.1 2.8 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 CEG49934.1 - 1.6 8.9 3.9 39 4.4 1.3 2.6 2 0 0 2 2 2 0 AAA domain DUF3533 PF12051.8 CEG49937.1 - 0.14 11.0 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) EI24 PF07264.11 CEG49938.1 - 8.3e-16 58.7 11.8 8.3e-16 58.7 11.8 1.7 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) RELT PF12606.8 CEG49938.1 - 1.1 8.3 5.0 7 5.7 5.0 2.3 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF4642 PF15484.6 CEG49939.1 - 0.016 15.4 3.5 0.03 14.6 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) CDC45 PF02724.14 CEG49939.1 - 6.5 4.9 12.4 7.8 4.7 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Choline_transpo PF04515.12 CEG49943.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter Metallophos PF00149.28 CEG49944.1 - 1e-12 49.0 0.0 1.9e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_17 PF00332.18 CEG49945.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TAF6_C PF07571.13 CEG49946.1 - 2.2e-25 88.8 0.0 8.4e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CEG49946.1 - 4.1e-16 58.9 0.5 1.1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) LRR_9 PF14580.6 CEG49946.1 - 3.2e-14 52.8 2.4 6.5e-14 51.8 0.6 2.4 2 1 0 2 2 2 1 Leucine-rich repeat C2 PF00168.30 CEG49946.1 - 3.4e-13 49.8 0.0 7.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 CEG49946.1 - 7.2e-12 44.9 9.6 1.1e-09 37.9 5.0 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEG49946.1 - 6.7e-06 26.4 9.4 0.019 15.4 2.1 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEG49946.1 - 0.19 12.4 6.9 27 5.9 0.1 4.7 3 0 0 3 3 3 0 Leucine Rich Repeat DUF349 PF03993.12 CEG49946.1 - 0.38 11.1 2.8 1.6 9.1 2.8 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) LRR_6 PF13516.6 CEG49946.1 - 6.6 7.1 9.6 3.4 8.0 0.6 3.4 3 0 0 3 3 3 0 Leucine Rich repeat A_thal_3526 PF09713.10 CEG49947.1 - 5e-24 84.3 0.6 8.7e-24 83.5 0.6 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF883 PF05957.13 CEG49948.1 - 0.0097 16.5 0.8 0.025 15.2 0.8 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) PHD PF00628.29 CEG49949.1 - 9.9e-08 31.8 7.3 9.9e-08 31.8 7.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-Di19 PF05605.12 CEG49949.1 - 0.0046 17.2 0.1 0.53 10.6 0.0 3.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PHD_Oberon PF07227.11 CEG49949.1 - 0.0048 16.8 2.3 0.0048 16.8 2.3 1.9 2 0 0 2 2 2 1 PHD - plant homeodomain finger protein DUF4428 PF14471.6 CEG49949.1 - 0.28 11.1 3.5 0.51 10.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) GATA PF00320.27 CEG49949.1 - 0.34 10.5 7.8 0.69 9.6 5.1 2.5 2 0 0 2 2 2 0 GATA zinc finger C1_1 PF00130.22 CEG49949.1 - 0.55 10.2 6.7 0.033 14.1 1.1 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-C2H2_12 PF18112.1 CEG49949.1 - 1.1 9.8 3.8 3.3 8.3 0.3 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_2 PF13639.6 CEG49949.1 - 3.7 8.0 7.3 11 6.4 7.3 1.9 1 0 0 1 1 1 0 Ring finger domain Clat_adaptor_s PF01217.20 CEG49950.1 - 9.6e-48 161.7 0.9 1.1e-47 161.5 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LBR_tudor PF09465.10 CEG49955.1 - 0.012 15.4 0.2 0.22 11.3 0.1 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain E3_UFM1_ligase PF09743.9 CEG49955.1 - 0.015 15.0 0.5 0.026 14.2 0.5 1.3 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 RVT_2 PF07727.14 CEG49956.1 - 3.7e-51 174.1 0.4 4.4e-51 173.9 0.4 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAA_hydro_N_2 PF18288.1 CEG49957.1 - 0.094 13.1 2.1 0.31 11.5 0.2 2.7 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF202 PF02656.15 CEG49960.1 - 0.0043 17.5 0.4 0.0043 17.5 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) L51_S25_CI-B8 PF05047.16 CEG49961.1 - 6.8e-10 38.7 0.1 1.2e-09 37.9 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FAM183 PF14886.6 CEG49962.1 - 6.3e-05 23.7 0.6 9.2e-05 23.1 0.2 1.5 2 0 0 2 2 2 1 FAM183A and FAM183B related SKN1 PF03935.15 CEG49963.1 - 2.2e-57 194.6 15.5 1.8e-37 128.9 9.2 4.7 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) ABC_membrane PF00664.23 CEG49965.1 - 1.9e-49 168.8 0.4 2.3e-49 168.5 0.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEG49965.1 - 6.3e-29 101.2 0.0 1.4e-28 100.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CEG49965.1 - 6.9e-08 32.2 0.3 2.8e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEG49965.1 - 0.002 18.5 0.2 0.0096 16.3 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEG49965.1 - 0.0023 18.2 0.1 0.066 13.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CEG49965.1 - 0.0025 17.7 0.1 0.0064 16.4 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 CEG49965.1 - 0.004 17.6 0.8 0.062 13.7 0.1 2.6 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEG49965.1 - 0.039 13.9 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 CEG49965.1 - 0.051 12.4 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CEG49965.1 - 0.057 13.7 0.2 0.83 9.9 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CEG49965.1 - 0.061 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CEG49965.1 - 0.064 13.0 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 CEG49965.1 - 0.067 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CEG49965.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 CEG49965.1 - 0.14 11.7 0.1 0.41 10.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF421 PF04239.12 CEG49966.1 - 0.014 15.1 1.0 0.014 15.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF421) PP2C_C PF07830.13 CEG49966.1 - 0.13 12.8 0.1 0.5 10.9 0.1 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Tfb4 PF03850.14 CEG49966.1 - 0.19 11.2 1.7 0.42 10.1 1.7 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 Suppressor_APC PF11414.8 CEG49966.1 - 0.24 11.5 8.6 1.2 9.3 0.6 3.5 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF5320 PF17253.2 CEG49966.1 - 0.26 12.4 3.2 24 6.1 0.9 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Rx_N PF18052.1 CEG49966.1 - 0.94 9.8 9.2 6.1 7.2 0.3 3.6 2 1 1 3 3 3 0 Rx N-terminal domain CENP-F_leu_zip PF10473.9 CEG49966.1 - 3.7 7.6 24.1 7.1 6.7 8.6 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 CEG49966.1 - 4.6 7.8 10.4 1.7 9.2 3.3 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Sugar_tr PF00083.24 CEG49968.1 - 1.3e-93 314.3 22.7 1.6e-93 314.1 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEG49968.1 - 2e-24 86.2 32.5 9.2e-19 67.6 8.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 CEG49970.1 - 2.8e-05 23.6 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG49970.1 - 0.016 14.8 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase YchF-GTPase_C PF06071.13 CEG49971.1 - 6.2e-32 109.6 0.0 1.5e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CEG49971.1 - 4.8e-25 87.9 0.3 2.2e-24 85.8 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG49971.1 - 2.9e-08 33.4 0.0 6.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 CEG49971.1 - 0.0022 17.1 0.0 0.0051 15.8 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CEG49971.1 - 0.013 15.7 0.0 0.12 12.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CEG49971.1 - 0.02 15.4 0.5 0.31 11.5 0.1 2.5 1 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 CEG49971.1 - 0.026 15.0 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CEG49971.1 - 0.031 14.3 0.1 0.17 12.0 0.1 2.3 1 1 0 1 1 1 0 Dynamin family Roc PF08477.13 CEG49971.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CEG49971.1 - 0.057 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CEG49971.1 - 0.061 13.7 0.1 0.18 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Hrs_helical PF12210.8 CEG49971.1 - 0.063 13.8 0.3 0.15 12.6 0.3 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate adh_short PF00106.25 CEG49972.1 - 4.7e-11 42.5 0.1 6.7e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG49972.1 - 7.2e-06 25.7 0.2 1.1e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.6 CEG49972.1 - 0.00025 20.4 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 CEG49972.1 - 0.0007 19.6 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CEG49972.1 - 0.058 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEG49972.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 CEG49972.1 - 0.091 12.6 0.1 0.32 10.8 0.1 1.7 1 1 1 2 2 2 0 YjeF-related protein N-terminus Sacchrp_dh_NADP PF03435.18 CEG49972.1 - 0.11 12.7 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Toprim_4 PF13662.6 CEG49972.1 - 0.13 12.8 0.1 5.7 7.5 0.0 2.3 1 1 1 2 2 2 0 Toprim domain Enoyl_reductase PF12241.8 CEG49976.1 - 0.079 12.3 0.1 0.087 12.2 0.1 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region DUF1672 PF07901.11 CEG49976.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) SelB-wing_3 PF09107.11 CEG49978.1 - 0.17 11.5 0.5 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF2766 PF10964.8 CEG49979.1 - 0.17 11.8 0.0 4.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) DUF3109 PF11307.8 CEG49983.1 - 0.026 14.3 0.8 0.065 13.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3109) EMP70 PF02990.16 CEG49984.1 - 8.2e-202 671.5 5.8 9.7e-202 671.2 5.8 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 C2 PF00168.30 CEG49985.1 - 3.3e-28 98.0 0.0 1.6e-13 50.8 0.0 2.4 3 0 0 3 3 3 2 C2 domain 60KD_IMP PF02096.20 CEG49987.1 - 1.5e-09 37.9 1.7 2.5e-09 37.3 1.7 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein adh_short_C2 PF13561.6 CEG49988.1 - 3.6e-44 151.1 0.1 4.5e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEG49988.1 - 3.4e-35 121.3 0.7 6.7e-35 120.3 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEG49988.1 - 5.9e-08 32.8 0.4 7.3e-08 32.5 0.4 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CEG49988.1 - 0.005 15.9 0.2 0.0077 15.3 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEG49988.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FYVE PF01363.21 CEG49989.1 - 2.5e-16 59.6 9.6 6.5e-16 58.2 9.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 CEG49989.1 - 0.0077 16.7 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 CEG49989.1 - 0.0079 16.4 6.4 0.0079 16.4 6.4 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Caudo_bapla16 PF16792.5 CEG49989.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Synaphin PF05835.12 CEG49989.1 - 0.096 13.0 1.8 0.18 12.1 1.8 1.4 1 0 0 1 1 1 0 Synaphin protein Zn-ribbon_8 PF09723.10 CEG49989.1 - 0.27 11.4 9.2 0.33 11.1 0.7 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Rhodanese_C PF12368.8 CEG49989.1 - 0.42 11.0 7.3 1.3 9.4 7.4 1.8 1 1 0 1 1 1 0 Rhodanase C-terminal UPF0515 PF15135.6 CEG49989.1 - 0.75 9.1 7.4 0.13 11.6 2.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 DZR PF12773.7 CEG49989.1 - 2.2 8.4 7.5 49 4.1 1.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon BT1 PF03092.16 CEG49990.1 - 2.7e-19 68.8 13.5 5.5e-12 44.7 0.2 3.6 3 1 1 4 4 4 3 BT1 family MFS_1 PF07690.16 CEG49990.1 - 3.1e-08 32.9 25.9 3.1e-08 32.9 25.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Nop14 PF04147.12 CEG49994.1 - 1.4 7.0 23.0 1.8 6.7 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_1 PF00515.28 CEG49995.1 - 3.9e-98 317.6 22.3 7.5e-10 38.2 1.3 12.2 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_2 PF07719.17 CEG49995.1 - 1.1e-75 243.8 26.0 1.6e-07 30.9 0.8 12.2 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_11 PF13414.6 CEG49995.1 - 8.1e-66 217.5 27.3 1.7e-08 34.0 0.3 12.1 5 2 7 12 12 12 11 TPR repeat TPR_8 PF13181.6 CEG49995.1 - 1.5e-53 174.6 11.7 3e-07 30.1 0.4 12.1 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_17 PF13431.6 CEG49995.1 - 1.4e-45 150.5 17.7 2e-05 24.6 0.0 11.5 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 CEG49995.1 - 4.7e-42 142.4 18.3 5.3e-10 39.8 0.0 7.2 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_9 PF13371.6 CEG49995.1 - 5.9e-39 132.1 19.6 5.4e-09 36.1 0.1 9.5 2 2 8 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 CEG49995.1 - 2.7e-33 114.1 30.8 2.6e-08 34.0 1.2 8.8 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_6 PF13174.6 CEG49995.1 - 6.2e-27 92.4 20.5 0.0073 16.9 0.3 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEG49995.1 - 2.2e-22 79.3 20.1 0.0014 19.1 0.0 8.3 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 CEG49995.1 - 6.3e-22 76.4 14.6 0.2 12.6 0.0 10.4 3 1 8 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 CEG49995.1 - 2.5e-17 61.5 28.3 0.0041 17.1 0.3 11.0 12 0 0 12 12 10 4 Tetratricopeptide repeat SHNi-TPR PF10516.9 CEG49995.1 - 2.2e-13 49.4 23.7 0.11 12.0 0.9 11.4 11 1 0 11 11 11 2 SHNi-TPR ANAPC3 PF12895.7 CEG49995.1 - 1.4e-12 47.6 22.1 0.02 15.1 0.8 6.2 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEG49995.1 - 8e-11 41.5 27.1 0.082 12.8 0.2 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat DUF3856 PF12968.7 CEG49995.1 - 9.6e-08 32.2 2.3 0.53 10.4 0.0 7.3 2 2 2 5 5 5 2 Domain of Unknown Function (DUF3856) MIT PF04212.18 CEG49995.1 - 1.9e-07 31.0 19.4 2.4 8.3 0.9 8.9 9 0 0 9 9 9 2 MIT (microtubule interacting and transport) domain BTAD PF03704.17 CEG49995.1 - 1.1e-06 29.1 10.3 2 8.9 0.1 5.5 2 1 3 5 5 5 2 Bacterial transcriptional activator domain NARP1 PF12569.8 CEG49995.1 - 2.4e-06 26.8 10.5 0.2 10.6 0.0 5.4 2 2 4 6 6 6 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 CEG49995.1 - 3.4e-06 27.0 10.1 0.00049 20.1 1.0 5.4 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CEG49995.1 - 1.8e-05 25.0 12.3 0.072 13.4 0.2 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 CEG49995.1 - 3e-05 23.6 0.4 0.082 12.3 0.0 3.5 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_15 PF13429.6 CEG49995.1 - 6.6e-05 22.2 10.0 2.5 7.3 0.1 6.9 2 2 7 9 9 9 1 Tetratricopeptide repeat TPR_5 PF12688.7 CEG49995.1 - 0.00012 22.2 5.2 0.09 13.0 0.1 5.2 4 1 1 5 5 5 1 Tetratrico peptide repeat TPR_4 PF07721.14 CEG49995.1 - 0.001 19.5 8.7 1.2 10.0 0.1 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat DHC_N2 PF08393.13 CEG49995.1 - 0.051 12.7 0.2 0.086 11.9 0.2 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF1257 PF06868.11 CEG49995.1 - 0.11 12.8 1.0 1.9 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1257) Flp_C PF05202.12 CEG49995.1 - 0.26 10.8 4.5 0.65 9.5 0.1 2.6 3 0 0 3 3 3 0 Recombinase Flp protein Ubie_methyltran PF01209.18 CEG49996.1 - 8.3e-85 283.8 0.0 1e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CEG49996.1 - 4.9e-18 65.6 0.0 3.7e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG49996.1 - 5.1e-17 62.3 0.0 1.7e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEG49996.1 - 3.5e-13 49.6 0.0 9.3e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEG49996.1 - 6.6e-13 49.3 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEG49996.1 - 6.8e-09 35.8 0.0 9.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEG49996.1 - 0.0069 16.3 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 CEG49996.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cucumo_2B PF03263.13 CEG49997.1 - 0.31 11.5 3.3 0.32 11.5 3.3 1.3 1 1 0 1 1 1 0 Cucumovirus protein 2B MFS_1 PF07690.16 CEG49998.1 - 1e-29 103.6 38.3 1e-29 103.6 38.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEG49998.1 - 4.7e-26 91.7 33.6 6.2e-26 91.3 33.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter EF-hand_8 PF13833.6 CEG49999.1 - 1.7e-22 79.0 6.5 2.9e-08 33.4 0.4 5.5 5 0 0 5 5 5 3 EF-hand domain pair Methyltransf_16 PF10294.9 CEG49999.1 - 3.6e-11 43.1 0.2 1.5e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Lysine methyltransferase EF-hand_1 PF00036.32 CEG49999.1 - 1.6e-08 33.5 10.5 8.9e-05 21.8 0.3 4.9 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 CEG49999.1 - 2.8e-08 34.1 5.6 0.022 15.2 0.7 4.5 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CEG49999.1 - 1.4e-07 30.8 14.6 0.00013 21.6 0.2 6.1 6 0 0 6 6 6 2 EF-hand domain Methyltransf_25 PF13649.6 CEG49999.1 - 4.9e-05 24.0 0.1 0.00038 21.1 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain SurA_N_2 PF13623.6 CEG49999.1 - 0.0022 17.9 0.4 0.43 10.4 0.3 2.5 2 0 0 2 2 2 1 SurA N-terminal domain EF-hand_5 PF13202.6 CEG49999.1 - 0.0024 17.3 0.4 0.0024 17.3 0.4 3.0 3 0 0 3 3 3 1 EF hand Cons_hypoth95 PF03602.15 CEG49999.1 - 0.0043 16.7 0.0 0.0095 15.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Hydrolase_6 PF13344.6 CEG49999.1 - 0.014 15.5 0.1 41 4.4 0.0 4.4 4 1 0 4 4 4 0 Haloacid dehalogenase-like hydrolase MTS PF05175.14 CEG49999.1 - 0.036 13.6 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Se-cys_synth_N PF12390.8 CEG49999.1 - 0.083 13.1 0.0 0.74 10.1 0.0 2.6 3 0 0 3 3 3 0 Selenocysteine synthase N terminal SurA_N_3 PF13624.6 CEG49999.1 - 0.1 12.4 1.7 0.42 10.4 0.7 2.4 3 0 0 3 3 3 0 SurA N-terminal domain EF-hand_8 PF13833.6 CEG50000.1 - 1.3e-05 25.0 0.1 3.4e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEG50000.1 - 0.0038 16.7 0.2 0.016 14.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEG50000.1 - 0.0064 16.3 1.6 0.034 14.1 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CEG50000.1 - 0.0089 16.5 1.3 0.046 14.2 1.3 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG50000.1 - 0.18 11.3 0.3 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 EF hand Trans_reg_C PF00486.28 CEG50001.1 - 1.2 9.3 4.5 12 6.0 0.1 3.4 3 2 0 3 3 3 0 Transcriptional regulatory protein, C terminal TatD_DNase PF01026.21 CEG50002.1 - 4.3e-38 131.1 0.0 4.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DUF3330 PF11809.8 CEG50002.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Herpes_UL52 PF03121.15 CEG50004.1 - 7.4e-11 41.8 0.2 2.4e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase PPL4 PF18188.1 CEG50004.1 - 0.17 11.8 0.7 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Prim-pol 4 DUF659 PF04937.15 CEG50005.1 - 0.038 13.8 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Cyt-b5 PF00173.28 CEG50008.1 - 2.2e-12 46.9 0.0 4.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 CEG50008.1 - 1.1e-05 25.2 1.1 1.8e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEG50008.1 - 0.008 16.0 2.1 0.025 14.4 2.1 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 CEG50008.1 - 0.085 13.4 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A 2OG-FeII_Oxy_2 PF13532.6 CEG50009.1 - 5.4e-20 72.4 0.0 6.3e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CEG50009.1 - 0.00011 22.6 0.0 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.25 CEG50010.1 - 1.1e-73 248.4 0.0 1.6e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2HCIx2C PF10782.9 CEG50012.1 - 0.079 12.9 0.5 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger PX PF00787.24 CEG50013.1 - 2.3e-18 66.2 0.8 7.8e-18 64.5 0.2 2.2 2 0 0 2 2 2 1 PX domain zf-RING_UBOX PF13445.6 CEG50013.1 - 1.4e-08 34.6 1.6 2.9e-08 33.6 1.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG50013.1 - 1.7e-07 31.1 4.1 3.2e-07 30.2 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEG50013.1 - 3e-07 30.6 3.5 3e-07 30.6 3.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CEG50013.1 - 2.6e-06 27.2 3.7 5.7e-06 26.1 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG50013.1 - 3.6e-05 23.5 1.9 8.9e-05 22.3 1.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEG50013.1 - 0.0011 19.1 1.4 0.0011 19.1 1.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG50013.1 - 0.0024 17.7 2.5 0.0063 16.3 2.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEG50013.1 - 0.017 15.4 2.3 0.046 14.0 2.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CEG50013.1 - 0.29 11.0 4.1 0.71 9.7 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CEG50013.1 - 1.1 9.1 9.7 8.2 6.4 9.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CBFD_NFYB_HMF PF00808.23 CEG50014.1 - 9.6e-07 29.0 2.2 0.0005 20.3 0.0 4.1 4 0 0 4 4 4 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pro_isomerase PF00160.21 CEG50015.1 - 1.6e-45 155.2 0.1 2.1e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 CEG50016.1 - 2.5e-17 62.4 0.0 5.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG50016.1 - 6.1e-05 22.8 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEG50016.1 - 0.00096 19.6 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain MBT PF02820.18 CEG50016.1 - 0.0012 19.1 0.2 0.0027 18.0 0.2 1.5 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 CEG50016.1 - 0.0031 17.4 0.8 0.0067 16.3 0.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Rad60-SLD_2 PF13881.6 CEG50016.1 - 0.17 12.0 0.5 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEG50016.1 - 0.31 11.6 2.8 1.2 9.8 0.0 2.8 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain CDC24 PF06395.11 CEG50018.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin BAG PF02179.16 CEG50020.1 - 8.1e-05 23.0 0.5 0.0002 21.7 0.5 1.7 1 1 0 1 1 1 1 BAG domain DUF2551 PF10826.8 CEG50020.1 - 0.024 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) W2 PF02020.18 CEG50022.1 - 1.6e-15 57.0 0.0 4.1e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NARP1 PF12569.8 CEG50022.1 - 0.26 10.1 16.1 0.39 9.6 16.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 CEG50022.1 - 0.36 9.1 5.8 0.46 8.7 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Lipoprotein_18 PF06804.11 CEG50022.1 - 0.41 9.7 6.2 0.59 9.1 6.2 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein RR_TM4-6 PF06459.12 CEG50022.1 - 1.1 9.0 9.9 1.7 8.4 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 CEG50022.1 - 3.6 6.0 17.3 4.8 5.6 17.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.9 CEG50022.1 - 7.8 5.5 9.1 11 5.0 9.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 CEG50023.1 - 3.4e-37 126.9 14.3 3e-13 50.1 2.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEG50023.1 - 2.2e-21 73.7 1.5 0.0033 17.8 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CEG50023.1 - 2.8e-20 71.8 8.9 0.00027 21.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CEG50023.1 - 1.5e-19 69.8 12.8 2.5e-06 27.6 0.2 5.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEG50023.1 - 3.7e-18 65.6 4.1 4.5e-06 27.1 0.2 4.6 1 1 3 5 5 5 4 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 CEG50024.1 - 2.1e-13 49.0 0.7 5.1e-05 22.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CEG50024.1 - 1.4e-11 44.6 5.9 2.7e-05 24.5 0.4 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEG50024.1 - 5.5e-11 41.2 6.6 9.5e-05 21.7 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEG50024.1 - 6.5e-11 41.9 5.8 1.5e-07 31.2 1.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CEG50024.1 - 8.6e-09 34.5 5.2 7.9e-05 22.0 1.0 2.5 2 0 0 2 2 2 2 EF hand RST PF12174.8 CEG50024.1 - 0.026 14.5 0.3 0.43 10.5 0.1 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 CEG50024.1 - 0.054 13.4 2.7 1.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF2802 PF10975.8 CEG50024.1 - 0.065 13.4 0.7 0.85 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) His_Phos_2 PF00328.22 CEG50025.1 - 9.4e-81 272.1 0.0 9.7e-45 153.5 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CEG50025.1 - 2.5e-29 101.3 0.5 6.3e-29 100.0 0.0 2.0 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CEG50025.1 - 3e-06 27.0 0.0 7.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 CEG50025.1 - 0.0025 17.5 0.3 1.7 8.3 0.0 3.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PAP_assoc PF03828.19 CEG50027.1 - 1e-13 51.3 0.1 2.5e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEG50027.1 - 0.041 14.2 0.0 0.2 12.0 0.0 2.2 1 1 0 1 1 1 0 Nucleotidyltransferase domain GH131_N PF18271.1 CEG50028.1 - 1.2e-52 179.1 0.4 1.4e-52 178.9 0.4 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 CEG50028.1 - 0.0002 21.3 0.2 0.00032 20.6 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide lyase GSG-1 PF07803.11 CEG50028.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 GSG1-like protein WD40 PF00400.32 CEG50029.1 - 4.3e-16 59.0 12.4 4.7e-05 24.1 1.3 4.7 3 1 1 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG50029.1 - 2.5e-07 30.9 0.5 0.099 13.0 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2_7 PF15269.6 CEG50029.1 - 0.047 13.8 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger Nup160 PF11715.8 CEG50029.1 - 0.07 11.8 0.0 0.41 9.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Kinesin PF00225.23 CEG50030.1 - 9.5e-100 333.7 0.0 9.5e-100 333.7 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEG50030.1 - 2.7e-42 144.2 0.0 2.7e-42 144.2 0.0 4.0 4 0 0 4 4 4 1 Microtubule binding Mce4_CUP1 PF11887.8 CEG50030.1 - 2 7.8 4.6 1.7 8.0 2.0 2.3 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative YabA PF06156.13 CEG50030.1 - 6.2 7.5 0.0 6.2 7.5 0.0 9.0 3 1 6 9 9 9 0 Initiation control protein YabA Filament PF00038.21 CEG50031.1 - 0.0011 18.6 20.4 0.0017 18.0 20.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein bZIP_1 PF00170.21 CEG50031.1 - 0.011 15.8 3.2 0.011 15.8 3.2 3.8 3 1 1 4 4 4 0 bZIP transcription factor ADIP PF11559.8 CEG50031.1 - 0.021 14.9 6.7 0.021 14.9 6.7 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Flexi_CP_N PF08358.10 CEG50031.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Carlavirus coat DUF1515 PF07439.11 CEG50031.1 - 0.097 12.7 5.6 0.25 11.4 2.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) UreE_C PF05194.12 CEG50031.1 - 0.21 12.1 0.8 1 9.9 0.1 2.3 1 1 0 2 2 2 0 UreE urease accessory protein, C-terminal domain Mod_r PF07200.13 CEG50031.1 - 0.57 10.3 23.1 1.6 8.8 10.4 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein STAT_alpha PF01017.20 CEG50031.1 - 1.2 9.0 22.6 0.057 13.3 7.6 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Sec2p PF06428.11 CEG50031.1 - 1.7 8.6 23.9 3.1 7.8 5.7 3.6 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Atg14 PF10186.9 CEG50031.1 - 1.9 7.5 15.9 2.1 7.4 15.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 CEG50031.1 - 2.3 6.1 12.4 4.7 5.1 12.0 1.6 1 1 0 1 1 1 0 Prominin WD-3 PF09765.9 CEG50031.1 - 3.4 6.9 10.2 6.6 6.0 8.4 1.8 1 1 1 2 2 2 0 WD-repeat region DASH_Dam1 PF08653.10 CEG50031.1 - 5 7.0 8.7 33 4.4 0.3 3.7 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF3106 PF11304.8 CEG50031.1 - 5.9 7.4 17.3 8.9 6.8 5.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) DUF2203 PF09969.9 CEG50031.1 - 7.7 7.3 12.4 1.7 9.4 4.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 CEG50031.1 - 7.8 6.5 28.8 1.9 8.6 14.9 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YtxH PF12732.7 CEG50031.1 - 7.9 7.1 7.5 6.5e+02 1.0 7.5 2.9 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 CEG50031.1 - 9.8 6.9 9.6 4.4 8.0 0.3 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Tweety PF04906.13 CEG50031.1 - 9.9 4.7 8.3 5.4 5.6 3.0 1.8 1 1 1 2 2 2 0 Tweety Smg4_UPF3 PF03467.15 CEG50032.1 - 8e-24 84.6 0.1 8e-24 84.6 0.1 2.2 1 1 1 2 2 2 1 Smg-4/UPF3 family Ras PF00071.22 CEG50033.1 - 1.7e-37 128.5 0.0 2.1e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG50033.1 - 2.7e-26 92.2 0.0 4.1e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG50033.1 - 7.8e-11 41.7 0.1 9.4e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG50033.1 - 0.00083 18.8 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEG50033.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CEG50033.1 - 0.0018 17.5 0.4 1.3 8.1 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 CEG50033.1 - 0.15 12.2 0.2 7.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Dynamin family YqaJ PF09588.10 CEG50034.1 - 0.01 16.0 0.1 0.035 14.3 0.1 2.2 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain SecA_SW PF07516.13 CEG50034.1 - 0.05 13.7 0.8 0.1 12.6 0.8 1.4 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Peptidase_S9_N PF02897.15 CEG50038.1 - 2.7e-112 375.6 1.9 4e-112 375.0 1.9 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CEG50038.1 - 1.9e-59 200.7 0.0 3.9e-59 199.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CEG50038.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 CEG50038.1 - 0.015 14.5 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CEG50038.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HTH_28 PF13518.6 CEG50039.1 - 1.9e-05 24.7 0.1 0.043 14.0 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain DDE_3 PF13358.6 CEG50039.1 - 0.00055 19.7 0.1 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEG50039.1 - 0.012 15.4 0.2 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 CEG50039.1 - 0.11 12.3 0.2 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_IclR PF09339.10 CEG50040.1 - 0.0096 15.7 0.6 0.48 10.3 0.3 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_23 PF13384.6 CEG50040.1 - 0.014 15.2 0.2 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain YfdX PF10938.8 CEG50040.1 - 0.043 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 YfdX protein Sigma54_DBD PF04552.13 CEG50040.1 - 0.056 13.2 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 Sigma-54, DNA binding domain HTH_Tnp_1_2 PF13022.6 CEG50040.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_Tc3_2 PF01498.18 CEG50040.1 - 0.22 11.8 1.6 1.6 9.0 0.0 3.1 4 0 0 4 4 4 0 Transposase DPM3 PF08285.11 CEG50041.1 - 3.1e-24 85.0 2.2 3.4e-24 84.8 2.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1686 PF07937.11 CEG50041.1 - 0.026 14.4 3.8 0.6 10.0 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) TF_Zn_Ribbon PF08271.12 CEG50042.1 - 6.7e-15 54.3 1.6 1.1e-14 53.6 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 CEG50042.1 - 0.0004 20.0 0.4 0.0011 18.6 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S27 zf-ribbon_3 PF13248.6 CEG50042.1 - 0.0056 16.0 1.6 0.15 11.6 0.1 2.4 2 0 0 2 2 2 1 zinc-ribbon domain Nudix_N_2 PF14803.6 CEG50042.1 - 0.022 14.6 2.4 0.1 12.6 2.2 2.0 1 1 1 2 2 2 0 Nudix N-terminal zf-RRN7 PF11781.8 CEG50042.1 - 0.03 14.0 1.9 0.057 13.1 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 CEG50042.1 - 0.11 12.5 0.9 0.18 11.8 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.13 CEG50042.1 - 2.9 7.6 7.7 18 5.1 6.2 2.4 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit MFS_1 PF07690.16 CEG50046.1 - 4.8e-18 65.2 22.6 4.8e-18 65.2 22.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.23 CEG50050.1 - 2e-39 134.2 3.9 4.9e-39 133.0 1.8 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEG50050.1 - 3.1e-21 75.7 0.2 9.4e-21 74.1 0.2 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain HELP PF03451.14 CEG50051.1 - 1.8e-38 130.2 0.4 6.7e-16 57.9 0.0 3.6 3 0 0 3 3 3 3 HELP motif WD40 PF00400.32 CEG50051.1 - 2.4e-30 104.1 64.5 0.0047 17.8 0.1 25.1 25 2 0 25 25 25 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG50051.1 - 6.7e-24 84.0 0.0 0.01 16.1 0.0 12.6 8 3 4 12 12 12 6 Anaphase-promoting complex subunit 4 WD40 domain Yippee-Mis18 PF03226.14 CEG50051.1 - 5.3e-13 49.1 0.2 1.6e-12 47.6 0.2 1.8 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ge1_WD40 PF16529.5 CEG50051.1 - 8.2e-05 21.7 0.1 0.8 8.6 0.0 4.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_7 PF13499.6 CEG50051.1 - 0.00018 21.9 0.8 0.0022 18.4 0.1 2.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG50051.1 - 0.00021 20.9 0.1 0.59 10.2 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEG50051.1 - 0.0017 17.8 2.5 2 8.2 0.0 3.7 4 0 0 4 4 4 2 EF hand IKI3 PF04762.12 CEG50051.1 - 0.0075 14.3 0.0 0.25 9.3 0.0 2.9 3 0 0 3 3 3 1 IKI3 family WD40_like PF17005.5 CEG50051.1 - 0.0087 15.4 0.9 0.7 9.2 0.0 3.9 4 1 1 5 5 5 1 WD40-like domain Nbas_N PF15492.6 CEG50051.1 - 0.088 12.1 3.4 1.1 8.5 0.0 4.0 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 CEG50051.1 - 0.19 10.7 0.0 30 3.5 0.0 3.2 3 0 0 3 3 3 0 Coatomer WD associated region RRM_1 PF00076.22 CEG50052.1 - 4.1e-38 129.0 0.0 5.5e-17 61.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG50052.1 - 6.7e-06 25.9 0.0 0.72 9.8 0.0 4.0 4 1 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CEG50052.1 - 0.015 14.9 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OS-D PF03392.13 CEG50052.1 - 0.023 14.8 1.0 0.048 13.8 1.0 1.4 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D RRM_7 PF16367.5 CEG50052.1 - 0.032 14.4 0.0 2.2 8.4 0.0 2.8 2 2 0 2 2 2 0 RNA recognition motif FYVE PF01363.21 CEG50053.1 - 2.9e-11 43.3 9.8 1.1e-10 41.5 9.8 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEG50053.1 - 0.011 15.9 2.0 0.18 12.0 3.0 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger SAPS PF04499.15 CEG50053.1 - 0.02 13.7 0.1 0.02 13.7 0.1 2.7 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein IBR PF01485.21 CEG50053.1 - 0.12 12.6 8.1 0.38 11.0 8.1 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PH PF00169.29 CEG50053.1 - 0.15 12.6 3.0 2.9 8.4 0.0 3.1 3 0 0 3 3 3 0 PH domain TMEM171 PF15471.6 CEG50056.1 - 9.3 5.1 8.3 22 3.9 7.5 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 Na_Pi_cotrans PF02690.15 CEG50060.1 - 1.4e-37 128.9 27.5 5.3e-21 75.2 5.0 3.1 2 1 1 3 3 3 2 Na+/Pi-cotransporter Phage_Coat_B PF05356.11 CEG50060.1 - 0.012 15.5 0.2 0.073 13.0 0.2 2.4 1 0 0 1 1 1 0 Phage Coat protein B PTP_tm PF18861.1 CEG50060.1 - 0.046 13.7 0.2 0.046 13.7 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Retrotrans_gag PF03732.17 CEG50062.1 - 7.8e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein TMEM132D_C PF15706.5 CEG50063.1 - 0.074 12.8 0.0 0.27 11.0 0.0 2.0 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ndc1_Nup PF09531.10 CEG50063.1 - 0.14 10.8 3.5 0.2 10.3 3.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FeoB_associated PF12669.7 CEG50063.1 - 0.23 11.9 1.5 0.62 10.5 1.5 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein vMSA PF00695.19 CEG50063.1 - 0.24 10.5 1.0 0.33 10.0 1.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DDHD PF02862.17 CEG50063.1 - 0.51 10.5 4.1 0.25 11.5 2.0 1.6 2 0 0 2 2 2 0 DDHD domain GREB1 PF15782.5 CEG50063.1 - 1 6.4 6.9 1.3 6.0 6.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CEG50063.1 - 1.6 7.7 7.4 2.9 6.8 7.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CEG50063.1 - 2.2 6.8 10.0 3.5 6.2 10.0 1.2 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 CEG50063.1 - 9.4 4.9 12.4 19 3.9 12.4 1.5 1 0 0 1 1 1 0 Presenilin AI-2E_transport PF01594.16 CEG50064.1 - 1.1e-12 47.8 19.5 1.1e-12 47.8 19.5 3.1 3 0 0 3 3 3 1 AI-2E family transporter DUF4975 PF16346.5 CEG50064.1 - 0.096 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Osmo_CC PF08946.10 CEG50065.1 - 0.045 14.0 1.3 0.22 11.8 1.3 2.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil FAD-oxidase_C PF02913.19 CEG50066.1 - 1.8e-62 211.2 0.0 2.7e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEG50066.1 - 4.3e-38 130.2 1.6 9.4e-38 129.1 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain Chromo PF00385.24 CEG50067.1 - 8.6e-11 41.6 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEG50067.1 - 0.00085 19.4 0.8 0.0016 18.6 0.8 1.5 1 1 0 1 1 1 1 Polycomb-like MTF2 factor 2 IQ PF00612.27 CEG50068.1 - 5.8e-05 22.5 8.1 0.019 14.7 1.3 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif Vasculin PF15337.6 CEG50068.1 - 0.6 11.0 7.2 0.44 11.4 2.2 3.3 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 DUF3522 PF12036.8 CEG50069.1 - 3.3e-53 180.8 5.3 3.3e-53 180.8 5.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) PAP2 PF01569.21 CEG50069.1 - 8.5e-22 77.4 9.4 8.5e-22 77.4 9.4 2.2 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CEG50069.1 - 0.0012 19.3 3.8 0.0012 19.3 3.8 3.1 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF212 PF02681.14 CEG50069.1 - 0.16 12.1 2.2 2.6 8.2 0.3 3.2 3 1 1 4 4 4 0 Divergent PAP2 family PAP2_3 PF14378.6 CEG50069.1 - 2.1 8.0 27.7 0.012 15.3 13.1 3.8 3 1 0 3 3 3 0 PAP2 superfamily DUF2779 PF11074.8 CEG50072.1 - 0.067 13.7 0.3 0.17 12.4 0.1 1.7 1 1 0 2 2 2 0 Domain of unknown function(DUF2779) Herpes_UL3 PF03369.13 CEG50072.1 - 0.11 13.0 1.8 0.16 12.5 0.3 1.9 2 1 1 3 3 3 0 Herpesvirus UL3 protein Cpn60_TCP1 PF00118.24 CEG50073.1 - 2.8e-21 75.7 0.0 5.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.18 CEG50073.1 - 4.9e-19 68.6 0.3 1.3e-06 27.9 0.0 3.3 1 1 2 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CEG50073.1 - 3e-17 62.5 10.0 3e-17 62.5 10.0 3.0 2 1 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 CEG50073.1 - 9.3e-06 26.3 1.3 0.047 14.6 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat PALP PF00291.25 CEG50074.1 - 1e-71 241.8 0.0 1.4e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3510 PF12022.8 CEG50074.1 - 2e-27 96.1 2.1 2.2e-27 96.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 CEG50074.1 - 6.2e-25 87.8 6.3 1.8e-24 86.3 6.3 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 pPIWI_RE_REase PF18154.1 CEG50074.1 - 0.019 14.9 0.4 0.47 10.4 0.0 3.0 3 0 0 3 3 3 0 REase associating with pPIWI_RE DUF1664 PF07889.12 CEG50074.1 - 0.17 12.0 1.9 0.59 10.2 1.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1843 PF08898.10 CEG50074.1 - 0.46 11.0 1.7 1.3 9.6 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) tRNA-synt_1c PF00749.21 CEG50076.1 - 3.7e-104 348.0 0.0 4.5e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Pkinase_Tyr PF07714.17 CEG50079.1 - 2e-57 194.4 0.0 3.5e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG50079.1 - 9.1e-48 162.9 0.0 1.5e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cofilin_ADF PF00241.20 CEG50079.1 - 9.1e-10 38.4 0.0 0.00031 20.5 0.0 2.9 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Kinase-like PF14531.6 CEG50079.1 - 0.00028 20.3 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG50079.1 - 0.0057 15.5 0.8 0.0091 14.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEG50079.1 - 0.0067 16.4 0.2 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG50079.1 - 0.035 13.4 0.1 0.093 12.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CEG50079.1 - 0.05 13.2 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FTA2 PF13095.6 CEG50079.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 LRR_8 PF13855.6 CEG50080.1 - 6.4e-10 38.7 13.3 1.1e-07 31.5 3.4 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CEG50080.1 - 6.1e-09 36.0 22.9 1.3e-06 28.6 0.2 5.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) WW PF00397.26 CEG50080.1 - 7.8e-06 25.9 4.7 7.8e-06 25.9 4.7 1.8 2 0 0 2 2 2 1 WW domain LRR_6 PF13516.6 CEG50080.1 - 7.2e-05 22.5 13.5 0.08 13.0 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 CEG50080.1 - 0.0011 18.5 4.8 0.0031 17.0 4.8 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 CEG50080.1 - 1.7 9.5 11.3 78 4.4 0.1 6.3 5 0 0 5 5 5 0 Leucine Rich Repeat HORMA PF02301.18 CEG50081.1 - 0.011 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 HORMA domain TFA2_Winged_2 PF18121.1 CEG50082.1 - 1.1e-11 44.3 0.1 2.8e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CEG50082.1 - 3.2e-08 33.7 0.1 1.3e-07 31.8 0.1 2.1 1 0 0 1 1 1 1 TFIIE beta subunit core domain CorA PF01544.18 CEG50083.1 - 2.7e-09 36.8 7.6 8e-09 35.2 6.5 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein HTH_40 PF14493.6 CEG50084.1 - 0.17 12.3 0.4 0.62 10.6 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RVT_2 PF07727.14 CEG50086.1 - 0.0091 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4542 PF15075.6 CEG50088.1 - 0.064 13.6 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) CAF1 PF04857.20 CEG50088.1 - 0.078 12.1 1.4 0.094 11.9 1.4 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease BRCA-2_OB1 PF09103.10 CEG50089.1 - 2.6e-28 98.5 0.1 1.3e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CEG50089.1 - 2.7e-15 56.5 0.1 9.3e-15 54.8 0.1 2.0 1 0 0 1 1 1 1 BRCA2, helical DUF4078 PF13300.6 CEG50089.1 - 0.0047 17.2 0.2 0.017 15.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4078) His_Phos_2 PF00328.22 CEG50092.1 - 5.9e-12 45.6 0.0 5.6e-06 25.9 0.0 3.0 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Elicitin PF00964.17 CEG50094.1 - 5.7e-07 29.5 4.8 1.1e-06 28.7 4.8 1.4 1 0 0 1 1 1 1 Elicitin Pkinase PF00069.25 CEG50095.1 - 2.7e-40 138.4 0.0 7.2e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50095.1 - 9.6e-19 67.7 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEG50095.1 - 0.00019 21.4 1.5 0.016 15.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CEG50095.1 - 0.00034 20.0 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-4CXXC_R1 PF10497.9 CEG50095.1 - 0.16 12.2 0.7 0.68 10.2 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 TrmO PF01980.16 CEG50096.1 - 6.4e-40 136.1 0.0 1.7e-39 134.7 0.0 1.8 1 0 0 1 1 1 1 tRNA-methyltransferase O Tudor-knot PF11717.8 CEG50096.1 - 0.0023 17.8 0.3 0.0093 15.8 0.2 2.1 1 1 1 2 2 2 1 RNA binding activity-knot of a chromodomain SRP54 PF00448.22 CEG50098.1 - 9.9e-54 182.0 0.1 2.4e-53 180.7 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CEG50098.1 - 4.3e-37 128.6 10.5 6.7e-37 128.0 10.5 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 CEG50098.1 - 1.1e-08 34.4 0.0 2.8e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 CEG50098.1 - 1.5e-06 28.3 0.4 5.6e-06 26.5 0.4 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 CEG50098.1 - 1.6e-05 25.4 0.0 9e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CEG50098.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CEG50098.1 - 0.00047 20.2 0.0 0.0053 16.8 0.0 2.6 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ETF PF01012.21 CEG50098.1 - 0.00088 19.2 0.3 0.2 11.5 0.0 2.7 2 1 0 2 2 2 1 Electron transfer flavoprotein domain NTPase_1 PF03266.15 CEG50098.1 - 0.0014 18.6 1.6 0.012 15.5 0.2 2.8 2 1 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 CEG50098.1 - 0.0021 18.1 0.5 0.015 15.4 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Fer4_NifH PF00142.18 CEG50098.1 - 0.0086 15.5 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 CEG50098.1 - 0.0094 15.7 1.3 0.091 12.5 0.0 3.1 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 CEG50098.1 - 0.011 16.2 0.8 0.038 14.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 CEG50098.1 - 0.043 13.7 0.3 0.7 9.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEG50098.1 - 0.056 13.4 0.1 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 CEG50098.1 - 0.063 13.6 1.2 0.43 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 CEG50098.1 - 0.086 13.3 0.0 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_4_2 PF13477.6 CEG50098.1 - 0.12 12.4 0.0 4 7.5 0.0 2.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like A_deaminase PF00962.22 CEG50099.1 - 1.1e-25 90.7 0.1 2.4e-20 73.1 0.1 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase G-alpha PF00503.20 CEG50100.1 - 1.7e-102 343.2 3.5 2.1e-102 342.9 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEG50100.1 - 1.7e-14 53.7 2.0 3.8e-11 42.8 0.2 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEG50100.1 - 0.0012 18.3 2.5 0.13 11.6 0.5 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEG50100.1 - 0.0038 17.4 2.2 1.5 9.0 0.4 3.1 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CEG50100.1 - 0.047 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEG50100.1 - 0.07 13.2 0.1 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEG50100.1 - 0.092 12.3 0.2 0.8 9.2 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Histone PF00125.24 CEG50101.1 - 1.3e-15 58.0 0.0 1.6e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 CEG50101.1 - 0.00045 20.7 0.0 0.00076 19.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CEG50101.1 - 0.001 19.3 0.1 0.0022 18.2 0.0 1.6 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CEG50101.1 - 0.025 14.6 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein PX PF00787.24 CEG50103.1 - 3.5e-06 27.0 0.0 9.4e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 PX domain DUF2451 PF10474.9 CEG50104.1 - 1.9e-51 175.1 0.1 4.3e-51 174.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CEG50104.1 - 2.3e-27 96.0 6.9 7.8e-27 94.3 6.9 1.9 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Metallophos PF00149.28 CEG50105.1 - 8.2e-35 121.2 0.6 1.3e-34 120.5 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CEG50105.1 - 9.4e-27 93.2 0.0 2e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CEG50105.1 - 5.4e-12 45.0 5.5 8.5e-05 22.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEG50105.1 - 6.7e-10 38.3 6.4 0.0011 18.9 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEG50105.1 - 1.1e-05 25.2 3.3 0.00032 20.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG50105.1 - 0.00053 20.1 1.2 0.0016 18.5 1.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEG50105.1 - 0.00058 20.5 3.0 0.089 13.7 0.2 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEG50105.1 - 0.0022 18.6 4.9 0.01 16.5 3.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG50105.1 - 0.0068 16.1 1.1 0.0068 16.1 1.1 3.7 2 1 2 4 4 4 1 TPR repeat TPR_17 PF13431.6 CEG50105.1 - 0.0078 16.5 1.1 0.13 12.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEG50105.1 - 0.015 15.5 5.3 1.2 9.5 1.5 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CEG50105.1 - 0.017 14.3 0.4 0.029 13.6 0.4 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat bPH_4 PF06713.11 CEG50105.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain MIT PF04212.18 CEG50105.1 - 0.41 10.7 4.8 1.4 9.1 0.2 2.7 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain MMS19_C PF12460.8 CEG50106.1 - 6.5e-05 22.2 7.7 0.053 12.6 0.1 4.7 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal OSK PF17182.4 CEG50106.1 - 0.093 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 OSK domain RasGEF_N_2 PF14663.6 CEG50106.1 - 0.76 10.2 4.5 12 6.3 0.7 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PALP PF00291.25 CEG50107.1 - 1.2e-30 106.9 0.3 1.7e-30 106.5 0.0 1.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Asp_protease_2 PF13650.6 CEG50108.1 - 1.2e-08 35.5 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEG50108.1 - 4.5e-08 33.5 0.2 7.8e-08 32.8 0.0 1.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEG50108.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEG50108.1 - 0.0025 18.1 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Phage_sheath_1N PF17481.2 CEG50108.1 - 0.077 13.5 0.1 0.096 13.2 0.1 1.2 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain IF4E PF01652.18 CEG50109.1 - 1.1e-41 142.3 0.3 1.4e-41 141.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Trehalase PF01204.18 CEG50110.1 - 3.6e-131 438.5 2.8 7.8e-131 437.4 2.8 1.4 1 1 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 CEG50110.1 - 0.00031 19.7 5.0 0.06 12.1 0.2 3.1 3 0 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain DUF2294 PF10057.9 CEG50110.1 - 0.031 14.4 0.1 0.08 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) TFIIS_M PF07500.14 CEG50111.1 - 3.2e-21 75.9 2.8 6.6e-21 74.9 2.8 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CEG50111.1 - 3.9e-17 61.8 4.5 7.4e-17 60.9 4.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CEG50111.1 - 5.8e-14 51.8 0.7 1.5e-13 50.5 0.7 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CTNNBL PF08216.11 CEG50111.1 - 0.0075 16.4 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear zf-DNL PF05180.12 CEG50111.1 - 0.011 15.7 1.3 0.03 14.3 1.3 1.7 1 0 0 1 1 1 0 DNL zinc finger Baculo_LEF5_C PF11792.8 CEG50111.1 - 0.19 11.4 0.7 0.39 10.4 0.7 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PHD_2 PF13831.6 CEG50112.1 - 1.3e-08 34.3 8.0 1.3e-08 34.3 8.0 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CEG50112.1 - 8.4e-05 22.4 12.3 0.00022 21.0 12.3 1.7 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 CEG50112.1 - 0.00052 19.5 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 C1_1 PF00130.22 CEG50112.1 - 0.004 17.0 6.1 0.004 17.0 6.1 2.6 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF668 PF05003.12 CEG50112.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) zf-piccolo PF05715.13 CEG50112.1 - 0.98 9.6 8.1 2.5 8.3 8.1 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger C1_2 PF03107.16 CEG50112.1 - 5.9 7.3 13.9 0.83 10.0 5.9 2.7 3 0 0 3 3 3 0 C1 domain Sec23_trunk PF04811.15 CEG50114.1 - 4.9e-72 242.4 0.0 6.9e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CEG50114.1 - 6.2e-28 97.4 0.0 1.4e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CEG50114.1 - 2.2e-22 78.8 1.7 4.6e-22 77.8 0.1 2.4 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEG50114.1 - 1.3e-16 60.3 6.2 2.5e-16 59.4 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEG50114.1 - 8e-06 25.7 5.5 1.1e-05 25.2 0.0 3.1 3 0 0 3 3 3 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CEG50114.1 - 0.049 13.0 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ORC4_C PF14629.6 CEG50116.1 - 1.1e-16 60.9 0.2 2e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 CEG50116.1 - 0.071 13.5 0.1 0.3 11.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DRMBL PF07522.14 CEG50118.1 - 2e-29 102.0 0.4 4.7e-29 100.8 0.4 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CEG50118.1 - 0.0015 18.1 0.1 0.0042 16.6 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 CEG50118.1 - 0.027 14.4 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CEG50118.1 - 0.056 13.4 0.2 0.097 12.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AAA_26 PF13500.6 CEG50119.1 - 4.2e-42 144.2 0.0 1.5e-41 142.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain DRTGG PF07085.12 CEG50119.1 - 2.7e-06 27.1 0.0 5.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 CEG50119.1 - 3.2e-06 27.2 0.2 3.7e-05 23.8 0.2 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ER_lumen_recept PF00810.18 CEG50120.1 - 1.5e-51 175.1 7.9 1.5e-51 175.1 7.9 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor Apq12 PF12716.7 CEG50120.1 - 0.003 17.5 1.5 0.003 17.5 1.5 3.1 3 1 0 3 3 3 1 Nuclear pore assembly and biogenesis PQ-loop PF04193.14 CEG50120.1 - 0.022 14.5 0.1 0.022 14.5 0.1 4.2 3 2 2 5 5 5 0 PQ loop repeat Octopine_DH PF02317.17 CEG50121.1 - 3.1e-39 134.5 0.0 4.9e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 CEG50121.1 - 0.0072 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CEG50121.1 - 0.021 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CEG50121.1 - 0.03 14.4 0.1 0.1 12.7 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 CEG50121.1 - 0.036 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 CEG50121.1 - 0.068 12.7 0.1 0.34 10.5 0.1 1.9 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 CEG50121.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDPD PF03009.17 CEG50125.1 - 8.8e-45 153.5 0.0 2.4e-44 152.0 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FGGY_N PF00370.21 CEG50126.1 - 2.3e-21 76.5 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEG50126.1 - 9e-21 74.5 0.2 2.6e-20 73.0 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain CBM9_1 PF06452.11 CEG50130.1 - 1.2e-09 38.4 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 CEG50130.1 - 5.5e-07 29.5 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding family 9 PTCB-BRCT PF12738.7 CEG50132.1 - 1e-32 111.8 2.2 8e-14 51.3 0.4 3.9 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CEG50132.1 - 6.3e-24 84.2 0.2 2.3e-07 31.1 0.0 5.0 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEG50132.1 - 1.9e-18 66.7 0.2 2.8e-07 30.8 0.0 4.4 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CEG50132.1 - 8.6e-09 35.4 1.3 0.0046 17.0 0.1 5.1 4 2 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CEG50132.1 - 2e-05 24.8 1.0 0.86 9.9 0.0 3.9 3 1 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 CEG50132.1 - 0.00069 19.5 0.1 2.2 8.2 0.0 3.3 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain TFCD_C PF12612.8 CEG50132.1 - 0.0066 16.3 0.1 0.068 13.0 0.0 2.3 1 1 1 2 2 2 1 Tubulin folding cofactor D C terminal Laminin_I PF06008.14 CEG50133.1 - 5.1e-05 23.1 5.9 5.3e-05 23.1 5.9 1.0 1 0 0 1 1 1 1 Laminin Domain I YbfN PF13982.6 CEG50133.1 - 0.0026 18.0 0.2 0.0047 17.2 0.1 1.5 1 1 0 1 1 1 1 YbfN-like lipoprotein NYD-SP28 PF14772.6 CEG50133.1 - 0.0068 16.4 3.4 0.0068 16.4 3.4 1.3 1 1 0 1 1 1 1 Sperm tail DUF725 PF05267.12 CEG50133.1 - 0.0071 16.3 1.2 0.0072 16.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF725) V-ATPase_G_2 PF16999.5 CEG50133.1 - 0.062 13.7 5.3 0.076 13.4 5.3 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Herpes_UL6 PF01763.16 CEG50133.1 - 0.11 11.0 3.1 0.12 10.8 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4226 PF10774.9 CEG50133.1 - 0.12 12.6 3.2 0.2 12.0 2.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Lge1 PF11488.8 CEG50133.1 - 0.16 12.2 5.2 0.23 11.6 5.2 1.4 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 UPF0242 PF06785.11 CEG50133.1 - 1.4 9.0 8.6 0.53 10.4 3.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FmiP_Thoc5 PF09766.9 CEG50134.1 - 3.9e-77 260.0 0.3 5.5e-77 259.5 0.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 CcdA PF07362.12 CEG50134.1 - 0.11 13.0 0.2 0.54 10.7 0.2 2.2 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA FYVE PF01363.21 CEG50138.1 - 3.6e-09 36.6 16.7 3.6e-09 36.6 16.7 2.5 2 0 0 2 2 2 1 FYVE zinc finger Vps39_2 PF10367.9 CEG50138.1 - 0.28 11.6 4.2 0.87 10.1 4.2 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Multi_ubiq PF14452.6 CEG50143.1 - 0.065 13.5 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Multiubiquitin RolB_RolC PF02027.17 CEG50145.1 - 0.0025 17.5 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 RolB/RolC glucosidase family Peptidase_C65 PF10275.9 CEG50146.1 - 2.2e-48 164.9 0.0 7.3e-43 146.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 CEG50146.1 - 0.02 15.4 0.0 0.057 13.9 0.0 1.9 1 1 0 1 1 1 0 OTU-like cysteine protease DUF4694 PF15765.5 CEG50146.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) CDP-OH_P_transf PF01066.21 CEG50147.1 - 1.7e-13 51.1 1.2 1.7e-13 51.1 1.2 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pox_P21 PF05313.12 CEG50148.1 - 0.034 13.7 1.1 0.034 13.7 1.1 1.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Ly49 PF08391.10 CEG50148.1 - 0.12 12.7 0.4 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Radical_SAM_C PF16199.5 CEG50149.1 - 2.2e-32 110.9 0.0 5.6e-32 109.6 0.0 1.7 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CEG50149.1 - 9.1e-18 65.2 0.2 1.1e-16 61.7 0.0 2.4 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CEG50149.1 - 2.4e-09 37.5 0.0 8.5e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG50149.1 - 5.7e-05 23.1 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG50149.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Piezo_RRas_bdg PF12166.8 CEG50150.1 - 9.9e-89 298.5 0.6 9.9e-89 298.5 0.6 2.4 3 0 0 3 3 3 1 Piezo non-specific cation channel, R-Ras-binding domain fn3 PF00041.21 CEG50150.1 - 2.2e-11 44.0 0.0 5.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain PH PF00169.29 CEG50150.1 - 0.00057 20.4 0.2 0.0024 18.3 0.2 2.1 1 0 0 1 1 1 1 PH domain Pur_ac_phosph_N PF16656.5 CEG50150.1 - 0.042 14.4 0.0 0.21 12.2 0.0 2.2 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain PolyA_pol_arg_C PF12626.7 CEG50151.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus HTH_17 PF12728.7 CEG50152.1 - 4e-05 23.7 0.1 0.12 12.6 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 CEG50152.1 - 0.0033 18.0 0.0 0.95 10.1 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.6 CEG50152.1 - 0.0066 16.2 0.1 0.75 9.7 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain AbiEi_4 PF13338.6 CEG50152.1 - 0.0088 16.2 0.2 1.3 9.3 0.2 2.7 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin HTH_11 PF08279.12 CEG50152.1 - 0.1 12.6 0.1 2 8.4 0.0 2.5 3 0 0 3 3 3 0 HTH domain HTH_38 PF13936.6 CEG50152.1 - 0.12 12.1 1.4 8.9 6.2 0.1 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain PWI PF01480.17 CEG50153.1 - 0.00045 20.5 0.1 0.00098 19.4 0.1 1.5 1 0 0 1 1 1 1 PWI domain zf-U11-48K PF05253.12 CEG50153.1 - 0.079 12.9 1.0 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Ank_2 PF12796.7 CEG50154.1 - 4.9e-30 104.0 2.0 3.3e-12 46.8 0.4 5.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG50154.1 - 1.8e-24 85.8 3.2 2.4e-07 31.1 0.1 5.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG50154.1 - 6.4e-22 77.3 9.2 0.00014 22.1 0.1 6.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG50154.1 - 6.2e-21 72.2 7.4 0.0009 19.5 0.0 8.3 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 CEG50154.1 - 1.1e-19 69.9 9.6 0.00016 22.0 0.1 7.3 7 0 0 7 7 7 4 Ankyrin repeat YTH PF04146.15 CEG50155.1 - 6e-25 88.1 0.8 3.5e-24 85.6 0.8 1.9 1 1 0 1 1 1 1 YT521-B-like domain AAA PF00004.29 CEG50156.1 - 8.9e-44 149.1 0.1 7e-38 130.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEG50156.1 - 2.1e-18 66.0 0.4 1.3e-17 63.5 0.3 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CEG50156.1 - 4e-13 49.6 0.0 2.6e-05 24.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEG50156.1 - 2.6e-12 47.2 9.4 3.5e-06 27.3 0.0 3.7 4 1 0 4 4 2 2 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CEG50156.1 - 6.8e-12 45.0 0.2 1.9e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain Torsin PF06309.11 CEG50156.1 - 1.1e-11 44.9 0.0 3.3e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 Torsin AAA_22 PF13401.6 CEG50156.1 - 4.9e-11 43.0 1.1 0.00081 19.7 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEG50156.1 - 9.7e-11 42.3 0.5 0.0002 21.8 0.1 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CEG50156.1 - 1.9e-07 31.2 0.0 0.0056 16.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEG50156.1 - 2e-06 28.3 0.5 0.19 12.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 CEG50156.1 - 2.1e-06 27.6 0.2 0.025 14.3 0.0 3.4 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 CEG50156.1 - 1.6e-05 24.5 0.7 0.54 9.7 0.0 3.5 3 0 0 3 3 3 2 PhoH-like protein ResIII PF04851.15 CEG50156.1 - 1.9e-05 24.8 1.3 0.0061 16.6 0.1 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CEG50156.1 - 2.7e-05 24.5 0.0 0.14 12.5 0.0 3.0 2 1 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 CEG50156.1 - 6.1e-05 22.8 0.7 0.21 11.3 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEG50156.1 - 8e-05 22.8 0.0 0.0031 17.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEG50156.1 - 0.00012 22.5 1.4 0.86 9.9 0.4 3.4 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEG50156.1 - 0.00025 20.8 0.1 0.66 9.7 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEG50156.1 - 0.00034 20.4 0.1 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 CEG50156.1 - 0.0004 20.4 0.3 0.73 9.8 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CEG50156.1 - 0.0022 17.3 2.9 0.47 9.7 0.0 3.4 4 0 0 4 4 3 1 Zeta toxin TIP49 PF06068.13 CEG50156.1 - 0.0026 17.0 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 CEG50156.1 - 0.0032 17.0 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 CEG50156.1 - 0.0034 16.5 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 CEG50156.1 - 0.0036 17.8 6.5 0.097 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CEG50156.1 - 0.0063 16.8 0.0 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CEG50156.1 - 0.0065 16.3 6.5 0.67 9.7 0.0 3.6 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 CEG50156.1 - 0.0078 15.6 0.3 0.15 11.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AFG1_ATPase PF03969.16 CEG50156.1 - 0.013 14.4 0.0 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_25 PF13481.6 CEG50156.1 - 0.015 14.8 1.6 6.7 6.2 0.1 3.3 3 1 0 3 3 2 0 AAA domain AAA_3 PF07726.11 CEG50156.1 - 0.016 15.1 0.2 1.1 9.2 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 CEG50156.1 - 0.017 14.9 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 CEG50156.1 - 0.019 14.2 0.7 1.6 7.9 0.0 3.1 2 1 0 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.27 CEG50156.1 - 0.023 15.2 5.2 5 7.6 0.0 3.9 3 1 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 CEG50156.1 - 0.024 14.3 3.0 1.8 8.2 0.0 3.4 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 CEG50156.1 - 0.029 14.3 0.1 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 NACHT domain FlxA PF14282.6 CEG50156.1 - 0.046 13.7 0.5 0.23 11.5 0.3 2.2 2 0 0 2 2 2 0 FlxA-like protein NTPase_1 PF03266.15 CEG50156.1 - 0.058 13.3 2.1 1.4 8.8 0.1 3.2 3 0 0 3 3 3 0 NTPase IPT PF01745.16 CEG50156.1 - 0.19 11.1 0.9 6.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Isopentenyl transferase ATPase PF06745.13 CEG50156.1 - 0.24 10.7 5.5 0.63 9.4 0.0 3.1 4 0 0 4 4 3 0 KaiC CRCB PF02537.15 CEG50158.1 - 2.9e-30 104.4 33.1 9.4e-17 61.1 5.1 4.2 3 1 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Pyr_redox_3 PF13738.6 CEG50158.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3347 PF11827.8 CEG50158.1 - 0.18 12.0 0.5 0.37 11.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Na_H_Exchanger PF00999.21 CEG50161.1 - 2.7e-10 39.6 40.6 2.2e-09 36.6 23.1 2.3 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family GWT1 PF06423.12 CEG50161.1 - 0.032 14.4 2.3 0.79 9.8 0.6 2.9 2 1 0 2 2 2 0 GWT1 Pyr_redox_3 PF13738.6 CEG50161.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SPW PF03779.14 CEG50161.1 - 2.5 7.7 8.9 1.6 8.4 1.3 3.0 2 0 0 2 2 2 0 SPW repeat Citrate_bind PF16114.5 CEG50162.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Na_H_Exchanger PF00999.21 CEG50164.1 - 2.1e-11 43.2 39.4 1.5e-09 37.2 27.0 2.3 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Pyr_redox_3 PF13738.6 CEG50164.1 - 0.00031 20.1 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SPW PF03779.14 CEG50164.1 - 6.3 6.5 8.5 2.3 7.9 1.7 2.9 2 0 0 2 2 2 0 SPW repeat SRI PF08236.11 CEG50166.1 - 0.015 15.5 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain PseudoU_synth_2 PF00849.22 CEG50167.1 - 9.1e-28 97.4 0.0 1.6e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TFIIS_M PF07500.14 CEG50167.1 - 0.044 14.3 0.1 0.087 13.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Ank_2 PF12796.7 CEG50168.1 - 1.2e-32 112.3 5.5 1.9e-08 34.8 0.1 7.5 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG50168.1 - 5.1e-25 87.5 16.8 5.4e-09 36.4 0.5 8.5 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG50168.1 - 3.2e-18 63.9 23.3 0.0073 16.7 0.0 12.5 13 0 0 13 13 13 5 Ankyrin repeat Ank_5 PF13857.6 CEG50168.1 - 2.9e-16 59.3 3.9 0.03 14.6 0.0 6.5 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CEG50168.1 - 3.4e-16 58.9 19.2 0.004 17.5 0.0 10.2 11 0 0 11 11 11 6 Ankyrin repeat TyeA PF09059.10 CEG50168.1 - 0.15 12.1 0.0 0.53 10.4 0.0 1.9 1 0 0 1 1 1 0 TyeA LRR_8 PF13855.6 CEG50169.1 - 0.011 15.5 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat YfkB PF08756.10 CEG50169.1 - 0.015 15.1 0.4 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 YfkB-like domain BT1 PF03092.16 CEG50170.1 - 2.8e-08 32.5 18.2 0.00038 18.8 6.4 3.0 2 1 0 2 2 2 2 BT1 family CBP_BcsF PF11120.8 CEG50170.1 - 0.035 14.2 0.7 0.43 10.7 0.2 2.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF ISK_Channel PF02060.15 CEG50170.1 - 2 8.1 4.3 0.46 10.2 0.2 2.0 3 0 0 3 3 3 0 Slow voltage-gated potassium channel DUF3671 PF12420.8 CEG50170.1 - 2.1 8.5 0.0 2.1 8.5 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function MotA_ExbB PF01618.16 CEG50170.1 - 2.7 7.7 5.0 20 5.0 0.3 2.4 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Abhydrolase_9_N PF15420.6 CEG50170.1 - 3 7.8 9.0 0.38 10.7 0.3 2.6 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Prim-Pol PF09250.11 CEG50172.1 - 0.026 14.9 0.0 0.038 14.4 0.0 1.4 1 1 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DUF365 PF04033.12 CEG50172.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) DPBB_1 PF03330.18 CEG50173.1 - 2.8e-09 37.1 0.0 7.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF5305 PF17231.2 CEG50173.1 - 0.00079 18.9 1.2 0.00089 18.7 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Barwin PF00967.17 CEG50173.1 - 0.014 15.3 0.9 0.029 14.2 0.9 1.6 1 0 0 1 1 1 0 Barwin family TMEM154 PF15102.6 CEG50173.1 - 0.83 9.6 5.5 0.07 13.0 0.4 1.7 2 0 0 2 2 2 0 TMEM154 protein family DPBB_1 PF03330.18 CEG50174.1 - 1.3e-08 34.9 0.2 3.5e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEG50174.1 - 0.0012 18.7 0.4 0.0022 17.9 0.4 1.4 1 0 0 1 1 1 1 Barwin family HTH_Tnp_Tc5 PF03221.16 CEG50175.1 - 1.6e-08 34.4 0.6 1.6e-08 34.4 0.6 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Atrophin-1 PF03154.15 CEG50175.1 - 0.21 9.9 6.7 0.27 9.5 6.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Rotamase_3 PF13616.6 CEG50176.1 - 2.3e-15 57.2 0.0 2.9e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CEG50176.1 - 1.2e-14 55.0 0.0 1.6e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CEG50176.1 - 0.013 16.3 0.0 0.014 16.2 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CEG50177.1 - 3.3e-38 130.8 0.0 3.4e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase PF00639.21 CEG50177.1 - 1.7e-35 121.9 0.1 2e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CEG50177.1 - 7.6e-11 42.9 0.0 0.00032 21.5 0.0 2.1 2 0 0 2 2 2 2 PPIC-type PPIASE domain SMC_hinge PF06470.13 CEG50177.1 - 0.043 14.1 0.0 5.3 7.4 0.0 2.2 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain DUF111 PF01969.17 CEG50179.1 - 3.4e-10 39.6 0.0 3.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF111 bPH_2 PF03703.14 CEG50179.1 - 0.057 13.6 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain DUF111 PF01969.17 CEG50180.1 - 4.8e-59 200.3 0.2 5.6e-59 200.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 DUF111 PF01969.17 CEG50181.1 - 4.2e-23 82.0 0.0 4.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 Spore_YunB PF09560.10 CEG50181.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) adh_short PF00106.25 CEG50182.1 - 3e-49 167.1 0.1 4.5e-49 166.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG50182.1 - 3.9e-32 111.7 0.0 5.6e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG50182.1 - 1.3e-12 48.0 0.1 2.2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CEG50182.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CEG50182.1 - 0.041 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEG50182.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PCI PF01399.27 CEG50183.1 - 1e-14 54.9 0.2 5.9e-14 52.5 0.0 2.5 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CEG50183.1 - 7e-13 48.4 3.0 2e-12 47.0 3.0 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain LPD5 PF18799.1 CEG50183.1 - 0.054 13.9 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 OSCP PF00213.18 CEG50183.1 - 0.2 11.8 4.4 0.26 11.4 0.4 2.7 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit Voldacs PF03517.13 CEG50184.1 - 5.3e-21 75.2 0.9 5.6e-11 42.7 0.0 2.3 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling RNB PF00773.19 CEG50185.1 - 1.6e-91 307.1 0.0 1.6e-91 307.1 0.0 2.6 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CEG50185.1 - 3.6e-17 62.2 0.0 1e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEG50185.1 - 1e-10 41.8 0.0 1e-10 41.8 0.0 3.1 2 1 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 CEG50185.1 - 5.8e-08 32.6 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CEG50185.1 - 0.00033 20.8 0.0 0.006 16.7 0.0 2.9 3 0 0 3 3 3 1 Cold shock domain Dapper PF15268.6 CEG50185.1 - 9.6 4.9 41.0 15 4.3 41.0 1.2 1 0 0 1 1 1 0 Dapper TFIIF_alpha PF05793.12 CEG50186.1 - 2.1e-26 92.6 22.6 1.9e-24 86.2 22.6 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1604 PF07713.13 CEG50186.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) FlxA PF14282.6 CEG50189.1 - 0.049 13.6 2.7 0.068 13.2 2.7 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF1192 PF06698.11 CEG50189.1 - 0.23 11.6 4.7 0.58 10.3 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Tctex-1 PF03645.13 CEG50190.1 - 1.1e-21 77.0 0.4 5e-21 74.9 0.1 1.8 2 0 0 2 2 2 1 Tctex-1 family NitrOD5 PF11537.8 CEG50190.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 Kinesin PF00225.23 CEG50191.1 - 2.5e-101 338.9 0.6 3.8e-101 338.3 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEG50191.1 - 1.2e-19 70.7 0.2 1.1e-18 67.6 0.0 2.9 2 1 0 2 2 2 1 Microtubule binding PH PF00169.29 CEG50191.1 - 2.6e-08 34.3 0.0 9.5e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 PH domain Kinesin_assoc PF16183.5 CEG50191.1 - 9.3e-05 22.7 0.6 0.00056 20.1 0.5 2.4 1 1 0 1 1 1 1 Kinesin-associated DUF3694 PF12473.8 CEG50191.1 - 0.0076 16.9 0.0 0.031 14.9 0.0 2.1 1 0 0 1 1 1 1 Kinesin protein SpoU_methylase PF00588.19 CEG50193.1 - 6.6e-23 81.4 0.2 9e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SAP PF02037.27 CEG50193.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 SAP domain ADH_N PF08240.12 CEG50194.1 - 8.6e-18 64.2 0.2 3.4e-17 62.3 0.2 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEG50194.1 - 2.4e-10 40.5 0.1 6.1e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEG50194.1 - 6.8e-07 29.0 0.2 1.6e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 CEG50194.1 - 0.0012 18.9 0.1 0.0052 16.9 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase zf-C2HE PF16278.5 CEG50194.1 - 0.04 14.4 0.1 0.15 12.6 0.1 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger ROS_MUCR PF05443.11 CEG50194.1 - 0.11 12.6 0.5 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_4 PF13894.6 CEG50194.1 - 0.17 12.8 1.0 0.58 11.1 1.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Mannitol_dh_C PF08125.13 CEG50195.1 - 1.6e-05 24.5 0.1 9.8e-05 21.9 0.1 2.1 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain NDK PF00334.19 CEG50196.1 - 2.5e-52 176.5 0.0 3.7e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase OMPdecase PF00215.24 CEG50196.1 - 0.16 11.5 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family WGR PF05406.15 CEG50197.1 - 2.5 8.2 6.1 2.6 8.2 0.6 2.3 1 1 1 2 2 2 0 WGR domain EF-1_beta_acid PF10587.9 CEG50197.1 - 3.6 8.1 15.2 0.52 10.8 5.4 2.9 2 1 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Borrelia_P83 PF05262.11 CEG50197.1 - 7 5.0 17.9 7.8 4.9 17.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RGS PF00615.19 CEG50198.1 - 5.4e-21 75.1 0.3 2.4e-20 73.0 0.3 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 CEG50198.1 - 1e-19 70.4 0.0 5.3e-15 55.3 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CEG50199.1 - 2.9e-213 704.6 67.8 3.6e-56 190.1 5.2 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CEG50199.1 - 1.2e-18 67.0 75.4 3.3e-05 22.8 0.9 11.0 7 4 2 11 11 11 10 Polycystin cation channel GPHH PF16905.5 CEG50199.1 - 2.8e-13 49.4 0.0 6.9e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF3935 PF13071.6 CEG50199.1 - 2.3 8.8 14.5 8.3 7.0 1.3 4.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3935) RRM_1 PF00076.22 CEG50200.1 - 2.6e-13 49.6 0.0 4.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOP5NT PF08156.13 CEG50200.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 NOP5NT (NUC127) domain RraA-like PF03737.15 CEG50201.1 - 2.8e-29 102.2 5.1 2.8e-29 102.2 5.1 1.5 2 0 0 2 2 2 1 Aldolase/RraA zf-BED PF02892.15 CEG50201.1 - 0.00031 20.7 0.1 0.00062 19.7 0.1 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 CEG50201.1 - 0.13 13.1 0.2 0.4 11.6 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger LON_substr_bdg PF02190.16 CEG50202.1 - 2.7e-09 37.2 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 CEG50202.1 - 5e-05 23.5 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Folliculin_C PF16692.5 CEG50202.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Folliculin C-terminal domain DUF2593 PF10767.9 CEG50203.1 - 0.083 12.9 0.1 0.12 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) DUF3081 PF11280.8 CEG50204.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) PH PF00169.29 CEG50205.1 - 1.5e-12 47.9 0.0 4.5e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 CEG50205.1 - 7.1e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEG50205.1 - 0.021 15.2 3.3 0.066 13.6 1.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 CEG50205.1 - 0.022 15.1 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MYND PF01753.18 CEG50206.1 - 3.9e-10 39.7 13.6 5.9e-10 39.1 13.6 1.3 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 CEG50206.1 - 5.5e-10 39.4 0.1 2.6e-05 24.4 0.0 2.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 CEG50206.1 - 1.4e-05 24.7 1.0 0.069 13.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEG50206.1 - 0.00049 20.7 0.9 4.9 8.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEG50206.1 - 0.00063 19.6 1.1 0.33 11.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEG50206.1 - 0.0026 17.7 0.3 14 6.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEG50206.1 - 0.01 15.6 0.2 20 5.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEG50206.1 - 0.014 15.5 0.2 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 CEG50206.1 - 0.094 13.0 0.2 2.5 8.6 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_5 PF12688.7 CEG50206.1 - 0.097 12.9 0.3 0.18 12.1 0.3 1.4 1 1 0 1 1 1 0 Tetratrico peptide repeat NGP1NT PF08153.12 CEG50207.1 - 3.7e-45 153.2 0.4 6.5e-45 152.5 0.4 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CEG50207.1 - 5e-18 65.2 0.2 5.3e-15 55.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEG50207.1 - 1.8e-06 27.5 0.0 3.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEG50207.1 - 2.7e-06 27.4 0.0 2.1e-05 24.5 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEG50207.1 - 0.00022 20.8 0.2 0.014 14.9 0.1 3.0 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CEG50207.1 - 0.00057 19.4 0.4 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CEG50207.1 - 0.0047 17.0 1.6 0.19 11.8 0.0 3.3 2 2 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CEG50207.1 - 0.0049 17.4 0.1 0.16 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 CEG50207.1 - 0.012 15.9 0.1 8.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEG50207.1 - 0.016 14.8 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain C2 PF00168.30 CEG50208.1 - 1.8e-06 28.2 0.0 4.1e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 C2 domain Peptidase_M16_M PF16187.5 CEG50209.1 - 9e-52 176.1 0.1 1.4e-50 172.2 0.0 2.5 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CEG50209.1 - 1.5e-30 106.2 0.4 6e-30 104.2 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEG50209.1 - 6.9e-17 62.0 0.0 1.1e-12 48.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Phage_int_SAM_1 PF02899.17 CEG50209.1 - 0.14 12.5 0.1 0.46 10.8 0.1 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Metallophos PF00149.28 CEG50210.1 - 1.6e-28 100.6 0.3 3.8e-28 99.4 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S8 PF00410.19 CEG50210.1 - 2.6e-21 75.9 0.1 6.8e-21 74.5 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S8 EF-hand_7 PF13499.6 CEG50210.1 - 1.2e-15 57.7 3.8 7.1e-05 23.2 0.1 5.0 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CEG50210.1 - 7.8e-13 47.2 3.1 0.021 14.7 0.0 5.8 5 0 0 5 5 4 3 EF-hand domain EF-hand_1 PF00036.32 CEG50210.1 - 3.6e-12 44.9 0.2 7.8e-05 21.9 0.1 5.2 4 0 0 4 4 4 3 EF hand FYVE PF01363.21 CEG50210.1 - 1.7e-11 44.1 19.1 1.7e-11 44.0 16.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger EF-hand_8 PF13833.6 CEG50210.1 - 2e-09 37.1 0.6 2.4e-06 27.3 0.2 4.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CEG50210.1 - 0.024 14.1 0.0 2.9 7.5 0.0 3.6 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 CEG50210.1 - 0.028 14.4 0.8 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand YajC PF02699.15 CEG50210.1 - 0.038 13.9 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 Preprotein translocase subunit RE_LlaMI PF09562.10 CEG50210.1 - 0.052 13.1 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 LlaMI restriction endonuclease MlaD PF02470.20 CEG50210.1 - 0.079 13.3 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 MlaD protein FYVE_2 PF02318.16 CEG50210.1 - 0.095 12.9 9.9 0.27 11.4 9.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Retrotran_gag_3 PF14244.6 CEG50210.1 - 0.11 12.3 0.4 27 4.7 0.0 3.9 4 0 0 4 4 4 0 gag-polypeptide of LTR copia-type PPP5 PF08321.12 CEG50210.1 - 0.13 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 PPP5 TPR repeat region Abhydrolase_4 PF08386.10 CEG50213.1 - 6.3e-07 29.5 0.1 2.7e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 CEG50213.1 - 1.2e-06 28.0 0.0 0.00021 20.6 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEG50213.1 - 1.4e-06 28.2 0.2 5.8e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEG50213.1 - 0.00032 21.4 0.0 0.0037 17.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sigma_reg_N PF13800.6 CEG50213.1 - 0.023 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Tetraspanin PF00335.20 CEG50214.1 - 8.1e-24 84.6 32.2 5.3e-16 59.0 18.4 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF2370 PF10176.9 CEG50214.1 - 0.045 13.4 0.7 2.5 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) DUF4184 PF13803.6 CEG50214.1 - 0.1 12.3 9.0 0.066 12.9 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) Rsm1 PF08600.10 CEG50214.1 - 0.35 11.1 1.9 0.46 10.7 1.0 1.6 1 1 0 1 1 1 0 Rsm1-like DHHC PF01529.20 CEG50214.1 - 0.52 10.4 19.7 0.27 11.4 7.0 3.3 2 1 1 3 3 3 0 DHHC palmitoyltransferase DUF4064 PF13273.6 CEG50214.1 - 1.9 8.8 0.0 1.9 8.8 0.0 5.1 2 1 1 4 4 4 0 Protein of unknown function (DUF4064) CH PF00307.31 CEG50215.1 - 9.7e-08 32.2 0.1 3.8e-07 30.3 0.1 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain SecD-TM1 PF13721.6 CEG50215.1 - 1.9 9.0 7.9 5.4 7.5 0.5 2.9 1 1 1 2 2 2 0 SecD export protein N-terminal TM region Bap31_Bap29_C PF18035.1 CEG50215.1 - 8.1 6.5 15.8 0.2 11.7 6.6 2.7 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RNA_pol_Rpb2_6 PF00562.28 CEG50216.1 - 6.8e-125 417.2 0.0 9.9e-125 416.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEG50216.1 - 1.3e-67 227.3 0.1 1.8e-67 226.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CEG50216.1 - 1.1e-51 175.1 0.0 1.8e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CEG50216.1 - 2e-33 114.6 0.1 6.6e-33 113.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CEG50216.1 - 3.4e-26 91.2 0.0 7.8e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CEG50216.1 - 8.4e-25 86.8 2.2 1.1e-24 86.4 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CEG50216.1 - 1.3e-13 51.3 2.5 3.7e-13 49.8 2.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FA_desaturase PF00487.24 CEG50217.1 - 9.7e-21 74.8 15.9 1.4e-20 74.3 15.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CEG50217.1 - 6e-18 64.0 1.8 1.1e-17 63.2 1.8 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Equine_IAV_S2 PF06502.11 CEG50218.1 - 0.091 12.9 1.2 0.13 12.3 1.2 1.5 1 1 0 1 1 1 0 Equine infectious anaemia virus S2 protein BT1 PF03092.16 CEG50219.1 - 7.6e-09 34.3 1.4 7.6e-09 34.3 1.4 2.2 2 0 0 2 2 2 1 BT1 family CHASE6_C PF17150.4 CEG50222.1 - 0.11 13.2 0.1 0.76 10.5 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain NRIP1_repr_3 PF15689.5 CEG50222.1 - 0.44 10.9 3.2 0.35 11.2 0.8 2.1 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Coq4 PF05019.13 CEG50223.1 - 1.9e-85 285.7 0.0 2.3e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pro-kuma_activ PF09286.11 CEG50225.1 - 1.8e-20 73.7 0.6 8.6e-20 71.5 0.1 2.5 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CEG50225.1 - 3.1e-07 30.0 0.3 5.1e-07 29.3 0.3 1.3 1 0 0 1 1 1 1 Subtilase family ParcG PF10274.9 CEG50226.1 - 1.1e-68 231.0 0.0 1.3e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein RWP-RK PF02042.15 CEG50227.1 - 1.9e-19 69.4 0.3 6.1e-19 67.7 0.3 1.9 1 0 0 1 1 1 1 RWP-RK domain UvrB_inter PF17757.1 CEG50227.1 - 0.081 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 UvrB interaction domain Sel1 PF08238.12 CEG50230.1 - 4.6e-47 157.4 26.8 4e-08 33.7 0.4 7.3 7 0 0 7 7 7 6 Sel1 repeat TPR_7 PF13176.6 CEG50230.1 - 0.008 16.1 6.5 8.9 6.6 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Tai4 PF16695.5 CEG50230.1 - 0.017 15.6 0.3 4.9 7.8 0.0 2.9 2 1 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein TPR_14 PF13428.6 CEG50230.1 - 0.048 14.5 13.0 3.1 8.9 0.4 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat fn3_3 PF14686.6 CEG50230.1 - 0.45 10.3 2.0 8.9 6.2 0.1 3.6 4 1 0 4 4 4 0 Polysaccharide lyase family 4, domain II WD40 PF00400.32 CEG50231.1 - 1.6e-22 79.4 15.2 5.6e-05 23.8 0.3 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG50231.1 - 3.7e-05 24.0 0.0 0.18 12.1 0.0 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Marek_SORF3 PF07153.11 CEG50231.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein HTH_Tnp_Tc5 PF03221.16 CEG50232.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEG50232.1 - 0.0004 20.0 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Ammonium_transp PF00909.21 CEG50235.1 - 2.6e-14 52.7 5.0 4e-14 52.1 5.0 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Vut_1 PF02592.15 CEG50235.1 - 0.019 15.3 2.6 2.2 8.6 1.9 2.2 2 0 0 2 2 2 0 Putative vitamin uptake transporter RseC_MucC PF04246.12 CEG50235.1 - 0.34 10.8 4.3 0.15 12.0 1.6 1.7 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ammonium_transp PF00909.21 CEG50237.1 - 1.2e-42 146.1 16.6 1.6e-42 145.6 16.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Asp_protease_2 PF13650.6 CEG50237.1 - 0.0001 22.8 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEG50237.1 - 0.028 14.2 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CEG50237.1 - 0.092 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RseC_MucC PF04246.12 CEG50237.1 - 0.21 11.5 0.3 0.59 10.1 0.1 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC CCDC53 PF10152.9 CEG50240.1 - 7.8e-59 198.5 3.1 2.4e-44 151.4 0.1 2.6 2 1 0 2 2 2 2 Subunit CCDC53 of WASH complex TFIID_30kDa PF03540.13 CEG50240.1 - 0.019 14.9 0.2 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit ALAD PF00490.21 CEG50241.1 - 2.3e-95 319.4 0.2 2.6e-95 319.2 0.2 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF1378 PF07125.11 CEG50241.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) tRNA-synt_1b PF00579.25 CEG50242.1 - 3.2e-20 72.7 0.0 4.7e-19 68.8 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 CEG50242.1 - 1.6e-16 60.2 1.1 4.3e-16 58.8 1.1 1.8 1 0 0 1 1 1 1 WHEP-TRS domain NTP_transf_2 PF01909.23 CEG50243.1 - 6.2e-06 26.4 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEG50243.1 - 0.00082 19.5 0.1 0.0023 18.1 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-CCCH_4 PF18044.1 CEG50243.1 - 0.0027 17.4 1.9 0.0064 16.3 1.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CEG50243.1 - 0.018 15.0 2.0 0.018 15.0 2.0 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEG50243.1 - 0.024 14.7 3.7 0.067 13.3 3.7 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CEG50243.1 - 0.16 12.5 3.4 0.5 10.9 3.4 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HHH_8 PF14716.6 CEG50244.1 - 4.8e-10 39.7 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Peptidase_S49 PF01343.18 CEG50244.1 - 0.026 14.5 0.4 0.039 13.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 Relaxase PF03432.14 CEG50244.1 - 0.034 13.7 2.8 0.048 13.3 2.8 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain COX16 PF14138.6 CEG50244.1 - 1.5 9.4 5.0 5.5 7.6 5.0 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 TRAP-gamma PF07074.12 CEG50244.1 - 2.8 7.4 4.4 4.1 6.9 4.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ESAG1 PF03238.13 CEG50247.1 - 0.085 12.3 0.3 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 ESAG protein Aldo_ket_red PF00248.21 CEG50248.1 - 2.1e-69 233.9 0.0 2.4e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pox_F17 PF04767.12 CEG50252.1 - 0.072 13.6 0.5 0.95 10.0 0.4 2.0 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein Nop PF01798.18 CEG50254.1 - 4.9e-89 297.8 0.1 4.9e-89 297.8 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CEG50254.1 - 1.9e-21 76.2 0.4 1.9e-21 76.2 0.4 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain HMA PF00403.26 CEG50256.1 - 8.1e-51 170.3 22.0 1.1e-13 51.4 0.2 7.7 7 0 0 7 7 7 7 Heavy-metal-associated domain Hydrolase PF00702.26 CEG50256.1 - 1.8e-47 162.4 0.2 4.2e-47 161.1 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEG50256.1 - 8.2e-41 139.5 0.8 2.6e-40 137.9 0.8 1.9 1 0 0 1 1 1 1 E1-E2 ATPase PseudoU_synth_2 PF00849.22 CEG50256.1 - 7e-26 91.2 0.0 1.6e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Hydrolase_3 PF08282.12 CEG50256.1 - 0.0004 20.2 4.1 0.037 13.7 0.4 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Beach PF02138.18 CEG50257.1 - 7.4e-93 310.9 0.0 7.4e-93 310.9 0.0 1.6 2 0 0 2 2 2 1 Beige/BEACH domain ELMO_CED12 PF04727.13 CEG50257.1 - 1.2e-33 116.8 0.3 3.4e-33 115.2 0.3 1.8 1 0 0 1 1 1 1 ELMO/CED-12 family Mob1_phocein PF03637.17 CEG50257.1 - 6.4e-28 97.9 0.2 1.7e-27 96.5 0.2 1.8 1 0 0 1 1 1 1 Mob1/phocein family DUF4704 PF15787.5 CEG50257.1 - 1e-15 57.7 0.5 4.6e-15 55.6 0.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 CEG50257.1 - 1.1e-09 38.2 0.0 2.9e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CEG50257.1 - 1.6e-06 28.4 0.0 4.7e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 CEG50257.1 - 0.011 16.5 0.7 17 6.5 0.0 4.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Methyltransf_4 PF02390.17 CEG50258.1 - 1.4e-49 167.9 0.0 1.7e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CEG50258.1 - 0.00016 22.3 0.0 0.00032 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEG50258.1 - 0.0013 18.3 0.0 0.0041 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CEG50258.1 - 0.0046 17.7 0.0 0.0098 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEG50258.1 - 0.0055 17.3 0.0 0.015 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CEG50258.1 - 0.0096 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 CEG50258.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CEG50258.1 - 0.12 12.4 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain VirionAssem_T7 PF11653.8 CEG50258.1 - 0.14 12.7 0.1 0.25 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein XPA_C PF05181.12 CEG50259.1 - 1.7e-12 47.1 0.0 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus PhnA_Zn_Ribbon PF08274.12 CEG50259.1 - 0.062 13.3 0.9 6 6.9 0.1 2.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon XPA_N PF01286.18 CEG50259.1 - 0.085 12.9 6.5 0.19 11.8 6.5 1.6 1 1 0 1 1 1 0 XPA protein N-terminal F-box PF00646.33 CEG50260.1 - 0.0054 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEG50260.1 - 0.014 15.2 0.1 0.044 13.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like Pyr_redox_3 PF13738.6 CEG50261.1 - 0.0072 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CEG50261.1 - 0.12 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding U-box PF04564.15 CEG50262.1 - 8.8e-13 48.2 0.1 1.7e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 U-box domain C2 PF00168.30 CEG50262.1 - 2.5e-09 37.4 0.0 1.4e-06 28.5 0.0 2.7 1 1 1 2 2 2 2 C2 domain zf-Nse PF11789.8 CEG50262.1 - 7.3e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CEG50262.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein EamA PF00892.20 CEG50263.1 - 6.4e-13 49.0 38.0 1.8e-06 28.1 20.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CEG50263.1 - 4.5e-08 33.0 6.8 4.5e-08 33.0 6.8 2.0 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 CEG50263.1 - 0.0024 17.3 9.0 0.0038 16.6 8.8 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family RabGAP-TBC PF00566.18 CEG50264.1 - 4.1e-59 199.8 0.1 5.6e-59 199.4 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SNARE_assoc PF09335.11 CEG50265.1 - 5.4e-17 62.4 4.7 1.1e-16 61.4 4.7 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF948 PF06103.11 CEG50267.1 - 0.0079 16.4 0.9 0.0096 16.2 0.9 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) SLATT_4 PF18186.1 CEG50267.1 - 0.049 13.3 0.5 0.054 13.1 0.5 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Vif PF00559.17 CEG50267.1 - 0.08 12.6 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein Phtf-FEM1B_bdg PF12129.8 CEG50268.1 - 1.1e-18 67.6 0.2 1.1e-18 67.6 0.2 2.7 3 0 0 3 3 3 1 Male germ-cell putative homeodomain transcription factor LicD PF04991.13 CEG50269.1 - 5e-10 39.9 1.8 1.3e-09 38.6 2.1 1.6 1 1 0 1 1 1 1 LicD family DUF659 PF04937.15 CEG50271.1 - 0.028 14.3 0.5 0.068 13.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Pkinase PF00069.25 CEG50272.1 - 2.1e-23 83.0 0.2 2.4e-23 82.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50272.1 - 1e-15 57.7 0.1 1.1e-15 57.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEG50273.1 - 7.3e-10 38.5 0.1 1.5e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 AdenylateSensor PF16579.5 CEG50273.1 - 1.8e-09 38.1 3.1 1.2e-08 35.4 2.7 2.3 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase PF00069.25 CEG50273.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zf-SAP30 PF13866.6 CEG50273.1 - 0.092 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger FYVE_2 PF02318.16 CEG50274.1 - 0.011 16.0 11.6 0.016 15.4 7.7 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger EFP PF01132.20 CEG50274.1 - 0.023 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain SHMT PF00464.19 CEG50275.1 - 3.5e-172 572.5 0.0 4.1e-172 572.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CEG50275.1 - 3.5e-05 23.2 0.0 9.5e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GMP_synt_C PF00958.22 CEG50276.1 - 3.6e-44 148.7 0.0 8.3e-44 147.6 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CEG50276.1 - 6.1e-34 117.5 0.0 9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CEG50276.1 - 1.7e-09 37.2 0.0 1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Peptidase_C26 PF07722.13 CEG50276.1 - 7.4e-06 25.9 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CEG50276.1 - 5e-05 22.3 0.0 0.00012 21.0 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CEG50276.1 - 7.5e-05 22.4 0.0 0.00029 20.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 CEG50276.1 - 0.00043 20.4 0.0 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 CEG50276.1 - 0.00047 19.7 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 CEG50276.1 - 0.0044 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase SNO PF01174.19 CEG50276.1 - 0.035 14.0 0.0 0.49 10.2 0.0 2.3 1 1 0 1 1 1 0 SNO glutamine amidotransferase family ATP_bind_3 PF01171.20 CEG50276.1 - 0.041 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Fur_reg_FbpA PF13076.6 CEG50276.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Fur-regulated basic protein A Gtr1_RagA PF04670.12 CEG50278.1 - 1.3e-99 332.3 0.2 1.6e-99 332.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CEG50278.1 - 6.4e-09 36.1 0.0 3.5e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG50278.1 - 8.5e-09 35.1 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CEG50278.1 - 2.1e-07 30.7 0.0 7.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CEG50278.1 - 6.7e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG50278.1 - 0.01 15.8 0.2 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CEG50278.1 - 0.026 14.3 0.2 0.081 12.7 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CEG50278.1 - 0.05 14.1 0.7 0.094 13.2 0.6 2.0 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 CEG50278.1 - 0.058 12.6 0.4 0.55 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CEG50278.1 - 0.067 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CEG50278.1 - 0.12 12.8 0.1 1.5 9.2 0.1 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAA_hydrolase PF01557.18 CEG50279.1 - 2.8e-59 200.4 0.0 3.2e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 CEG50279.1 - 0.19 11.6 0.9 0.45 10.4 0.3 1.8 2 0 0 2 2 2 0 KH domain TraY PF05509.11 CEG50282.1 - 0.16 12.0 0.5 0.25 11.4 0.5 1.2 1 0 0 1 1 1 0 TraY domain Ank_2 PF12796.7 CEG50283.1 - 8.1e-35 119.3 0.8 2.2e-13 50.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEG50283.1 - 5.6e-31 106.5 0.6 4.5e-08 33.5 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEG50283.1 - 1.9e-29 101.3 0.5 4.1e-07 30.2 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEG50283.1 - 8.5e-28 93.3 0.2 0.00088 19.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 CEG50283.1 - 3.7e-25 87.2 2.5 0.0005 20.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat RRM_1 PF00076.22 CEG50284.1 - 4.6e-23 80.8 0.0 7.6e-13 48.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEG50284.1 - 4.2e-05 23.3 0.0 0.84 9.5 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CEG50284.1 - 0.00024 21.1 0.0 0.002 18.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RBM39linker PF15519.6 CEG50284.1 - 0.45 11.6 2.2 0.54 11.4 0.0 2.2 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein SWIRM-assoc_2 PF16496.5 CEG50284.1 - 5.6 5.7 10.3 8 5.2 10.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Sel1 PF08238.12 CEG50285.1 - 4.6e-44 147.9 22.9 5.4e-07 30.1 0.2 11.0 11 0 0 11 11 11 9 Sel1 repeat TPR_7 PF13176.6 CEG50285.1 - 0.00052 19.9 3.2 8.1 6.7 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG50285.1 - 0.011 16.0 2.9 2.9 8.5 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEG50285.1 - 0.35 10.8 1.6 13 5.8 0.4 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CEG50285.1 - 1.1 9.3 4.0 87 3.3 0.1 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SRP-alpha_N PF04086.13 CEG50286.1 - 5.8 6.7 12.0 7.1 6.5 12.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF-1a PF01176.19 CEG50287.1 - 1.8e-11 43.6 0.1 3.3e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 VASt PF16016.5 CEG50288.1 - 2.3e-27 96.3 0.4 2.3e-27 96.3 0.4 2.1 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain FCH PF00611.23 CEG50288.1 - 9.3e-13 48.3 2.9 3e-10 40.2 0.7 3.4 3 0 0 3 3 3 2 Fes/CIP4, and EFC/F-BAR homology domain GRAM PF02893.20 CEG50288.1 - 1.4e-11 44.2 0.2 5.3e-11 42.4 0.2 2.0 1 0 0 1 1 1 1 GRAM domain RUN PF02759.19 CEG50288.1 - 6.4 6.7 6.6 10 6.1 0.0 4.1 5 1 0 5 5 5 0 RUN domain Ribosomal_L7Ae PF01248.26 CEG50289.1 - 1.1e-22 79.6 0.4 2.3e-22 78.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CEG50289.1 - 0.0048 17.0 0.2 0.03 14.4 0.2 2.0 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF2817 PF10994.8 CEG50290.1 - 2.6e-71 240.8 0.0 3e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) zf-RING_2 PF13639.6 CEG50291.1 - 8.6e-08 32.4 7.6 1.9e-07 31.3 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEG50291.1 - 3.3e-05 24.1 6.7 8.7e-05 22.7 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 CEG50291.1 - 0.00019 21.5 7.2 0.00048 20.2 7.2 1.7 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 CEG50291.1 - 0.0019 18.2 1.8 0.0042 17.1 1.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CEG50291.1 - 0.0061 16.4 5.4 0.015 15.2 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG50291.1 - 0.0066 16.3 5.5 0.017 14.9 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG50291.1 - 0.019 14.8 7.0 0.053 13.4 7.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG50291.1 - 0.24 11.5 4.4 1.4 9.0 1.9 2.9 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 CEG50291.1 - 0.55 10.4 8.2 2.5 8.3 8.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CEG50291.1 - 0.95 9.3 6.1 2.4 8.0 6.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glucan_synthase PF02364.15 CEG50292.1 - 2.3e-187 624.8 9.9 7.6e-166 553.6 5.7 2.8 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEG50292.1 - 6.5e-25 87.9 3.2 1.1e-23 84.0 0.8 3.4 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 EF-hand_5 PF13202.6 CEG50292.1 - 0.017 14.6 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 EF hand Glucan_synthase PF02364.15 CEG50294.1 - 1.1e-185 619.3 17.7 4.4e-163 544.5 13.1 3.0 1 1 1 2 2 2 2 1,3-beta-glucan synthase component EF-hand_5 PF13202.6 CEG50294.1 - 0.0059 16.0 0.0 0.84 9.2 0.0 2.6 2 0 0 2 2 2 2 EF hand Mago_nashi PF02792.14 CEG50295.1 - 0.039 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Mago nashi protein CCT PF06203.14 CEG50297.1 - 8.5e-09 35.3 10.0 1.5e-08 34.5 10.0 1.4 1 0 0 1 1 1 1 CCT motif Period_C PF12114.8 CEG50297.1 - 0.19 11.3 3.2 0.3 10.7 3.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pro_isomerase PF00160.21 CEG50302.1 - 1.2e-41 142.6 0.0 4.3e-41 140.8 0.0 2.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MORN PF02493.20 CEG50302.1 - 0.00028 20.6 45.5 0.026 14.4 1.9 8.7 9 0 0 9 9 9 5 MORN repeat PIF3 PF05006.12 CEG50306.1 - 0.035 14.2 0.1 0.037 14.1 0.1 1.0 1 0 0 1 1 1 0 Per os infectivity factor 3 zf-CSL PF05207.13 CEG50307.1 - 6.6e-23 80.2 2.1 7.7e-23 80.0 2.1 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 CEG50307.1 - 0.033 14.4 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Kinesin PF00225.23 CEG50308.1 - 1.4e-113 379.2 1.8 1.4e-113 379.2 1.8 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG50308.1 - 3.4e-31 108.2 0.2 1.7e-30 105.9 0.2 2.3 1 0 0 1 1 1 1 Microtubule binding DUF4530 PF15039.6 CEG50308.1 - 0.049 13.8 0.1 0.049 13.8 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4530) PRT_C PF08372.10 CEG50308.1 - 6.5 6.5 7.3 2.1 8.1 0.4 2.5 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal Methyltransf_16 PF10294.9 CEG50309.1 - 2.1e-12 47.1 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase VWA_2 PF13519.6 CEG50310.1 - 9.4e-24 84.1 0.1 4.1e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 CEG50310.1 - 3.8e-08 33.4 0.0 5.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 CEG50310.1 - 8.8e-07 29.3 0.1 1.5e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 CEG50310.1 - 0.26 11.3 2.0 0.48 10.4 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif MAGE_N PF12440.8 CEG50310.1 - 4.8 7.9 9.3 13 6.5 9.3 1.8 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal Pkinase PF00069.25 CEG50311.1 - 9.7e-56 189.0 0.0 1.3e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50311.1 - 8.1e-27 94.1 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG50311.1 - 8.7e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEG50311.1 - 0.0005 19.0 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 CEG50311.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.23 CEG50311.1 - 0.0018 18.2 0.0 0.0036 17.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 CEG50311.1 - 0.012 16.4 0.6 0.027 15.2 0.6 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 CEG50311.1 - 0.016 14.2 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CEG50311.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain MINDY_DUB PF04424.13 CEG50312.1 - 9.8e-31 106.2 0.5 2.3e-30 105.0 0.5 1.7 1 0 0 1 1 1 1 MINDY deubiquitinase CAMSAP_CC1 PF17095.5 CEG50312.1 - 0.019 14.8 1.9 0.061 13.2 1.9 1.9 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin NADH-u_ox-rdase PF10785.9 CEG50313.1 - 1.1e-19 70.9 0.1 1.5e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH-u_ox-rdase PF10785.9 CEG50314.1 - 3e-24 85.5 0.1 3.5e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit RVT_2 PF07727.14 CEG50318.1 - 1.9e-39 135.7 0.0 2.5e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CEG50320.1 - 3.9e-07 30.0 0.1 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) A_deamin PF02137.18 CEG50320.1 - 0.019 14.4 0.4 0.029 13.9 0.4 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Crr6 PF08847.11 CEG50320.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 Chlororespiratory reduction 6 5-FTHF_cyc-lig PF01812.20 CEG50325.1 - 1.5e-44 152.1 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF1216 PF06746.11 CEG50326.1 - 0.0086 16.1 0.1 0.0086 16.1 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1216) TolA_bind_tri PF16331.5 CEG50326.1 - 2 8.5 15.8 0.47 10.6 1.4 5.0 5 1 0 5 5 5 0 TolA binding protein trimerisation HMMR_C PF15908.5 CEG50326.1 - 6.1 7.1 17.4 5.6 7.2 0.2 4.5 2 1 3 5 5 5 0 Hyaluronan mediated motility receptor C-terminal UPF0121 PF03661.13 CEG50332.1 - 3.4e-56 190.4 12.4 4.3e-56 190.0 12.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 CEG50332.1 - 1.2e-13 50.1 4.5 0.00035 20.5 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEG50332.1 - 3.2e-12 45.7 5.1 0.00042 20.0 0.2 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEG50332.1 - 2.9e-09 37.0 1.2 0.0076 17.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEG50332.1 - 5e-07 29.3 0.7 0.002 17.7 0.0 2.9 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 CEG50332.1 - 7.4e-06 26.2 0.3 0.0092 16.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEG50332.1 - 0.00024 21.7 3.3 0.027 15.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEG50332.1 - 0.00046 20.3 0.8 0.041 14.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEG50332.1 - 0.0006 19.8 3.2 0.46 10.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEG50332.1 - 0.0014 18.8 0.3 0.73 10.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 CEG50332.1 - 0.0015 19.0 1.2 0.11 12.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 CEG50332.1 - 0.02 15.4 2.9 0.83 10.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 CEG50332.1 - 0.067 13.4 0.6 0.3 11.4 0.1 2.1 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_21 PF09976.9 CEG50332.1 - 0.07 12.8 0.8 0.13 12.0 0.5 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 CEG50332.1 - 0.12 12.4 0.2 3.1 7.9 0.2 2.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 CEG50332.1 - 0.26 11.4 3.3 5.4 7.2 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CEG50332.1 - 0.89 9.5 6.1 25 4.9 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat SLC3A2_N PF16028.5 CEG50332.1 - 1.1 8.8 4.1 28 4.4 1.2 2.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus SNF2_N PF00176.23 CEG50333.1 - 2.8e-59 200.6 1.4 5.4e-59 199.7 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEG50333.1 - 5.7e-20 71.7 0.0 2.9e-19 69.4 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 CEG50333.1 - 2.6e-15 56.0 2.8 7.1e-07 29.0 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CEG50333.1 - 9.6e-06 25.7 0.0 4.9e-05 23.4 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEG50333.1 - 4.9e-05 23.2 0.0 0.00023 21.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ENTH PF01417.20 CEG50335.1 - 7.3e-14 51.9 0.0 9.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CEG50335.1 - 4.3e-08 32.5 0.0 5.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF2897 PF11446.8 CEG50336.1 - 0.021 14.7 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Staphostatin_A PF09022.10 CEG50340.1 - 0.055 13.4 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Staphostatin A DUF3417 PF11897.8 CEG50343.1 - 0.22 12.0 1.7 7 7.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Ntox1 PF15500.6 CEG50343.1 - 1.7 9.0 7.6 4.1 7.8 0.2 2.9 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 GRIM-19 PF06212.12 CEG50344.1 - 0.07 13.1 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 GRIM-19 protein M16C_assoc PF08367.11 CEG50346.1 - 8.2e-52 175.8 0.1 2e-51 174.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CEG50346.1 - 1e-20 74.5 0.1 2.2e-15 57.1 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEG50346.1 - 1.9e-08 34.4 0.0 1.6e-07 31.4 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) zf-RING_2 PF13639.6 CEG50347.1 - 4.1e-12 46.2 9.8 4.1e-12 46.2 9.8 2.0 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 CEG50347.1 - 4.8e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 CEG50347.1 - 9.5e-08 32.2 11.6 5.1e-07 29.9 11.6 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEG50347.1 - 8e-07 28.8 7.4 8e-07 28.8 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG50347.1 - 1.8e-06 27.9 8.7 5e-06 26.4 8.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEG50347.1 - 2.1e-06 27.6 8.1 3.6e-06 26.8 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CEG50347.1 - 5.1e-06 26.1 7.0 5.1e-06 26.1 7.0 2.8 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 CEG50347.1 - 7.8e-06 25.7 2.0 7.8e-06 25.7 2.0 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEG50347.1 - 9.6e-06 25.6 3.1 2.7e-05 24.1 3.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CEG50347.1 - 0.00012 21.9 5.6 0.00012 21.9 5.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG50347.1 - 0.00036 20.3 11.0 0.00036 20.3 11.0 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEG50347.1 - 0.014 15.0 6.6 0.014 15.0 6.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type OrfB_Zn_ribbon PF07282.11 CEG50347.1 - 0.081 12.9 3.8 14 5.7 0.1 3.4 2 1 1 3 3 3 0 Putative transposase DNA-binding domain FANCL_C PF11793.8 CEG50347.1 - 0.21 11.8 9.0 0.9 9.8 9.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CEG50347.1 - 4.2 7.6 9.3 48 4.2 9.3 2.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CHCH PF06747.13 CEG50348.1 - 2.2e-05 24.5 2.4 5.1e-05 23.3 2.4 1.6 1 0 0 1 1 1 1 CHCH domain Rhodanese_C PF12368.8 CEG50348.1 - 0.017 15.4 8.9 0.071 13.5 9.1 1.7 1 1 1 2 2 2 0 Rhodanase C-terminal DUF3128 PF11326.8 CEG50348.1 - 0.056 13.8 0.7 0.056 13.8 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3128) Sel1 PF08238.12 CEG50349.1 - 1.6e-37 127.1 32.3 2.2e-05 25.0 0.2 11.8 11 1 0 11 11 11 9 Sel1 repeat TPR_17 PF13431.6 CEG50349.1 - 0.029 14.8 1.2 30 5.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEG50349.1 - 0.089 13.5 11.8 27 5.7 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Peptidase_S74 PF13884.6 CEG50350.1 - 2.8e-14 53.2 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase EGF_2 PF07974.13 CEG50350.1 - 6.9e-07 29.5 30.7 0.00011 22.5 9.6 2.5 2 0 0 2 2 2 2 EGF-like domain Lactamase_B_3 PF13483.6 CEG50350.1 - 0.015 15.2 0.0 0.35 10.7 0.0 2.9 3 0 0 3 3 3 0 Beta-lactamase superfamily domain DHR10 PF18595.1 CEG50350.1 - 0.45 10.6 7.5 0.83 9.7 7.5 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain EGF PF00008.27 CEG50350.1 - 1.2 9.5 20.0 4.9 7.6 5.7 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 CEG50350.1 - 4.9 7.4 27.0 0.086 13.0 8.1 2.6 2 0 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 CEG50350.1 - 6.9 7.5 17.7 2.8 8.7 6.0 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF DASH_Spc19 PF08287.11 CEG50351.1 - 0.007 16.3 1.6 0.012 15.5 0.1 2.0 1 1 1 2 2 2 1 Spc19 PX PF00787.24 CEG50351.1 - 0.012 15.6 0.7 0.062 13.3 0.7 2.0 1 1 0 1 1 1 0 PX domain Pyr_redox_2 PF07992.14 CEG50352.1 - 4.7e-63 213.1 1.0 9.4e-63 212.2 0.6 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEG50352.1 - 7.4e-31 106.7 0.3 1.6e-30 105.6 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 CEG50352.1 - 1.4e-18 67.3 0.3 1.6e-17 63.7 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEG50352.1 - 1.4e-18 67.2 2.1 8.8e-18 64.6 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEG50352.1 - 9.6e-07 28.2 0.0 0.0013 17.9 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CEG50352.1 - 4.9e-06 25.5 0.4 0.18 10.4 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 CEG50352.1 - 5.1e-05 23.0 5.9 0.0086 15.7 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEG50352.1 - 0.00016 21.2 0.1 0.00038 19.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEG50352.1 - 0.00039 19.6 4.2 0.0019 17.3 0.7 2.7 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CEG50352.1 - 0.0013 18.0 0.3 0.012 14.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.19 CEG50352.1 - 0.0047 16.3 1.1 0.84 9.0 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 CEG50352.1 - 0.0054 16.9 1.0 0.0054 16.9 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CEG50352.1 - 0.0082 16.1 4.5 0.2 11.7 0.1 3.0 2 2 1 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CEG50352.1 - 0.015 14.6 1.0 0.83 8.9 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CEG50352.1 - 0.019 14.0 2.6 2 7.4 0.0 3.2 2 2 0 2 2 2 0 Lycopene cyclase protein DUF3251 PF11622.8 CEG50352.1 - 0.047 13.3 0.0 0.21 11.2 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3251) GIDA PF01134.22 CEG50352.1 - 0.089 11.9 1.5 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 CEG50352.1 - 0.091 12.6 2.9 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CEG50352.1 - 0.099 13.1 0.1 0.67 10.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain zf-TAZ PF02135.16 CEG50353.1 - 5.3e-07 30.0 12.5 1.2e-06 28.8 12.5 1.6 1 0 0 1 1 1 1 TAZ zinc finger CBFD_NFYB_HMF PF00808.23 CEG50355.1 - 8.5e-05 22.8 0.6 0.00023 21.4 0.6 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 CEG50355.1 - 0.0057 16.7 0.2 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF728 PF05304.12 CEG50355.1 - 0.0074 16.1 3.7 0.012 15.5 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF728) AA_kinase PF00696.28 CEG50356.1 - 1.5e-39 136.1 0.0 2.8e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family Fringe PF02434.16 CEG50356.1 - 0.042 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Fringe-like ACT_7 PF13840.6 CEG50356.1 - 0.14 11.9 0.4 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 ACT domain Guanylate_cyc PF00211.20 CEG50358.1 - 5e-10 39.3 0.0 8.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RSN1_7TM PF02714.15 CEG50359.1 - 1.4e-10 40.9 8.1 1.4e-10 40.9 8.1 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEG50359.1 - 5.5e-05 23.5 0.1 0.0029 17.9 0.5 2.6 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 CEG50359.1 - 0.0025 16.7 0.1 0.017 14.0 0.1 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel RRM_1 PF00076.22 CEG50359.1 - 0.007 16.2 0.0 0.62 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2178 PF09946.9 CEG50359.1 - 9 6.5 9.8 0.4 10.9 2.6 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DDE_1 PF03184.19 CEG50361.1 - 7.4e-37 126.7 0.0 1.4e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 CEG50361.1 - 2.6e-07 30.5 0.1 0.00032 20.5 0.0 2.7 3 0 0 3 3 3 2 DDE superfamily endonuclease Pox_F12L PF03337.13 CEG50361.1 - 0.062 11.4 0.0 0.083 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein DEAD PF00270.29 CEG50373.1 - 1.7e-24 86.5 0.1 4.1e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEG50373.1 - 8.5e-21 74.4 0.1 1.7e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 CEG50373.1 - 2.6e-07 31.2 5.9 0.12 13.3 0.0 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF5446 PF17522.2 CEG50373.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) ResIII PF04851.15 CEG50373.1 - 0.093 12.7 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CorA PF01544.18 CEG50373.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SpoIIE PF07228.12 CEG50374.1 - 6e-08 32.8 0.1 1.2e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CEG50374.1 - 2.5e-06 27.3 0.2 4.3e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Alba PF01918.21 CEG50374.1 - 0.093 12.6 0.3 0.21 11.4 0.3 1.5 1 0 0 1 1 1 0 Alba PP2C PF00481.21 CEG50374.1 - 0.18 11.4 1.3 12 5.4 0.3 2.2 1 1 1 2 2 2 0 Protein phosphatase 2C Pro_isomerase PF00160.21 CEG50375.1 - 2e-50 171.2 0.0 2.5e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4485 PF14846.6 CEG50376.1 - 0.14 12.3 3.5 7 6.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) ALMT PF11744.8 CEG50376.1 - 3.6 6.3 8.3 3.5 6.3 8.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C3HC4_3 PF13920.6 CEG50377.1 - 4.8e-12 45.5 15.6 9.4e-12 44.6 15.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG50377.1 - 2.7e-07 30.3 14.6 6e-07 29.2 14.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 CEG50377.1 - 0.00029 20.9 1.0 0.00029 20.9 1.0 3.0 3 1 1 4 4 4 1 K-box region RRM_1 PF00076.22 CEG50377.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRM1_C PF08767.11 CEG50378.1 - 5.1e-117 390.6 8.5 6e-117 390.4 1.2 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CEG50378.1 - 4.3e-35 121.0 8.4 4.3e-35 121.0 8.4 3.1 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CEG50378.1 - 2.1e-30 104.2 2.9 6e-30 102.7 2.9 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CEG50378.1 - 3.4e-30 103.9 1.7 3.4e-30 103.9 1.7 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CEG50378.1 - 3.6e-17 61.6 0.3 8.3e-17 60.4 0.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CEG50378.1 - 7.6e-12 45.0 0.2 4.3e-11 42.6 0.2 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain SpoIIIAH PF12685.7 CEG50382.1 - 6.9 6.4 10.1 41 3.9 10.1 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein PUB PF09409.10 CEG50384.1 - 2.6e-33 113.8 0.5 9.1e-12 44.7 0.0 4.8 4 0 0 4 4 4 4 PUB domain TUDOR_5 PF18359.1 CEG50384.1 - 1.5e-17 63.0 34.2 0.0023 17.6 0.2 8.5 9 0 0 9 9 9 6 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 CEG50384.1 - 1.5e-16 60.7 17.7 0.068 13.3 0.0 9.3 4 2 6 10 10 10 6 SGF29 tudor-like domain Tudor_3 PF18115.1 CEG50384.1 - 1e-14 54.1 14.1 0.0068 16.2 0.1 8.1 8 0 0 8 8 8 6 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CEG50384.1 - 2.4e-11 43.9 17.2 0.82 10.2 0.0 9.6 9 0 0 9 9 9 3 Agenet domain DUF4537 PF15057.6 CEG50384.1 - 3.7e-11 43.1 11.1 0.0049 16.9 0.0 6.3 3 2 4 7 7 7 4 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 CEG50384.1 - 5.9e-11 42.4 23.8 0.84 9.6 0.1 8.4 6 2 2 8 8 8 6 Tumour suppressor p53-binding protein-1 Tudor EF-hand_6 PF13405.6 CEG50384.1 - 1e-08 34.4 0.2 0.02 14.8 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CEG50384.1 - 1.3e-07 30.6 0.6 0.12 12.0 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CEG50384.1 - 2.6e-06 27.8 2.3 0.0017 18.8 0.3 3.8 2 1 1 3 3 3 2 EF-hand domain pair TUDOR PF00567.24 CEG50384.1 - 0.00028 20.9 6.5 6.7 6.8 0.0 5.8 5 3 2 7 7 7 2 Tudor domain Tudor_2 PF18104.1 CEG50384.1 - 0.0055 16.4 25.2 0.068 12.9 0.0 6.9 8 0 0 8 8 8 2 Jumonji domain-containing protein 2A Tudor domain EF-hand_8 PF13833.6 CEG50384.1 - 0.0075 16.1 1.5 3.1 7.7 0.2 4.0 4 0 0 4 4 4 1 EF-hand domain pair TERT_thumb PF17984.1 CEG50384.1 - 0.043 13.7 1.2 15 5.4 0.1 3.3 1 1 2 3 3 3 0 Telomerase reverse transcriptase thumb DNA binding domain Bac_A_amyl_C PF18612.1 CEG50384.1 - 3.7 7.4 5.0 76 3.2 0.2 4.2 3 0 0 3 3 3 0 Bacterial Alpha amylase C-terminal domain PH PF00169.29 CEG50385.1 - 1.5e-12 48.0 0.3 9.2e-12 45.4 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 CEG50385.1 - 0.00096 19.4 0.0 0.004 17.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 CEG50385.1 - 0.0027 17.8 0.1 0.58 10.3 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEG50385.1 - 0.036 14.5 0.6 0.88 10.0 0.6 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain BCNT PF07572.12 CEG50385.1 - 0.8 9.8 3.6 1.1 9.3 1.8 2.2 2 0 0 2 2 2 0 Bucentaur or craniofacial development MnmE_helical PF12631.7 CEG50387.1 - 0.056 13.6 7.1 0.27 11.4 0.0 3.3 1 1 2 3 3 3 0 MnmE helical domain ALS_ss_C PF10369.9 CEG50387.1 - 0.13 12.5 2.0 0.42 10.9 0.1 2.9 3 0 0 3 3 3 0 Small subunit of acetolactate synthase Cdc13_OB4_dimer PF18233.1 CEG50387.1 - 3.9 7.7 9.9 3.4 7.9 0.2 4.1 4 1 0 4 4 4 0 Cdc13 OB4 dimerization domain 6PF2K PF01591.18 CEG50388.1 - 1.2e-66 224.3 0.0 1.7e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEG50388.1 - 6.1e-37 127.2 0.0 1.6e-36 125.8 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AMPK1_CBM PF16561.5 CEG50388.1 - 1.1e-24 86.5 0.0 2.1e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AAA_33 PF13671.6 CEG50388.1 - 7.3e-08 32.7 0.0 1.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEG50388.1 - 0.053 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEG50388.1 - 0.087 13.4 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CEG50388.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CBM_48 PF02922.18 CEG50388.1 - 0.15 12.4 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Methyltransf_16 PF10294.9 CEG50389.1 - 1.1e-20 74.1 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase SpoIIIAH PF12685.7 CEG50390.1 - 0.2 11.4 11.3 0.68 9.7 5.3 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF349 PF03993.12 CEG50390.1 - 3 8.2 8.3 2.1 8.7 4.2 3.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) Pkinase PF00069.25 CEG50392.1 - 5.3e-52 176.8 0.0 7.5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50392.1 - 3.4e-23 82.2 0.0 5.2e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEG50392.1 - 0.0037 16.3 0.2 0.0056 15.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEG50392.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEG50392.1 - 0.035 14.0 0.4 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEG50392.1 - 0.076 12.3 0.4 0.14 11.5 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG50392.1 - 0.086 12.1 0.0 0.23 10.7 0.0 1.7 2 1 0 2 2 2 0 Kinase-like PALP PF00291.25 CEG50394.1 - 8.3e-70 235.5 0.0 9.4e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 CEG50394.1 - 0.041 13.9 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Myb_DNA-binding PF00249.31 CEG50395.1 - 1.9e-11 44.0 0.6 3.8e-11 43.0 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEG50395.1 - 0.00054 19.8 0.7 0.0015 18.3 0.7 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CEG50395.1 - 0.00095 19.4 0.2 0.0027 17.9 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain U1snRNP70_N PF12220.8 CEG50395.1 - 0.046 14.4 0.1 0.14 12.8 0.1 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Radical_SAM PF04055.21 CEG50397.1 - 0.006 17.0 0.0 0.0068 16.8 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily SUKH_6 PF14568.6 CEG50398.1 - 2.4e-17 63.5 1.5 2.9e-17 63.2 1.5 1.1 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 CEG50398.1 - 1.7e-12 47.3 0.2 2.2e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 CEG50398.1 - 1.8e-10 41.4 0.5 2.4e-10 40.9 0.5 1.2 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 CEG50399.1 - 2.2e-05 24.9 0.7 3e-05 24.4 0.7 1.2 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 CEG50399.1 - 0.0015 18.9 0.6 0.0041 17.5 0.6 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 CEG50399.1 - 0.0036 17.0 0.2 0.0084 15.8 0.2 1.8 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall Sod_Fe_N PF00081.22 CEG50404.1 - 1.2e-33 115.4 0.9 1.7e-33 114.9 0.9 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CEG50404.1 - 0.00095 19.3 0.5 0.0029 17.7 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain VIT PF08487.10 CEG50404.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain His_Phos_1 PF00300.22 CEG50406.1 - 1.1e-14 54.5 0.0 3.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PH PF00169.29 CEG50406.1 - 5.5e-07 30.1 0.0 9.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG50406.1 - 0.00083 19.6 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain FYVE PF01363.21 CEG50408.1 - 1.2e-06 28.5 10.0 3.1e-06 27.2 10.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger Vfa1 PF08432.10 CEG50408.1 - 0.5 10.7 3.7 1.1 9.5 3.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FYVE_2 PF02318.16 CEG50408.1 - 1.5 9.1 5.4 4 7.7 5.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger RXT2_N PF08595.11 CEG50408.1 - 1.7 8.7 5.7 5.9 6.9 5.7 1.9 1 1 0 1 1 1 0 RXT2-like, N-terminal zinc_ribbon_6 PF14599.6 CEG50410.1 - 4.4e-22 77.8 3.2 4.4e-22 77.8 3.2 2.6 2 1 1 3 3 3 1 Zinc-ribbon zf-RING_2 PF13639.6 CEG50410.1 - 1e-08 35.3 10.2 1e-08 35.3 10.2 2.6 2 2 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CEG50410.1 - 0.00028 20.8 10.2 0.00028 20.8 10.2 3.3 2 2 1 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 CEG50410.1 - 0.00051 19.9 9.9 0.00051 19.9 9.9 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG50410.1 - 0.00055 19.7 8.1 0.00055 19.7 8.1 3.1 2 2 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG50410.1 - 0.00085 19.1 15.5 0.00094 19.0 2.3 3.0 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG50410.1 - 0.0015 18.8 9.1 0.0015 18.8 9.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEG50410.1 - 0.0048 16.7 12.0 0.0048 16.7 12.0 3.3 2 2 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG50410.1 - 0.017 15.1 9.0 0.017 15.1 9.0 2.9 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_11 PF17123.5 CEG50410.1 - 0.018 14.8 7.4 0.018 14.8 7.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger FeS PF04060.13 CEG50410.1 - 0.042 13.5 3.2 0.56 9.9 0.1 2.8 2 0 0 2 2 2 0 Putative Fe-S cluster zf-LITAF-like PF10601.9 CEG50410.1 - 0.081 13.2 16.4 5.4 7.3 0.7 3.3 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-RING_4 PF14570.6 CEG50410.1 - 0.36 10.7 18.1 0.72 9.7 8.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CEG50410.1 - 0.84 9.7 9.8 0.56 10.3 4.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.29 CEG50410.1 - 2.4 8.1 15.0 1.6 8.7 6.8 3.0 2 2 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 CEG50410.1 - 4.8 6.9 13.0 0.13 11.9 4.5 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF3336 PF11815.8 CEG50411.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) MMR_HSR1 PF01926.23 CEG50412.1 - 1e-14 54.6 0.0 7.2e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG50412.1 - 9e-08 32.2 0.4 0.0015 18.5 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CEG50412.1 - 1.1e-06 28.2 0.1 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEG50412.1 - 0.00097 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Septin PF00735.18 CEG50412.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.5 2 0 0 2 2 2 1 Septin Roc PF08477.13 CEG50412.1 - 0.0053 17.0 0.1 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CEG50412.1 - 0.068 12.5 0.0 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 AIG1 family TIR_3 PF18567.1 CEG50412.1 - 0.83 9.7 2.9 7 6.7 0.9 2.4 1 1 1 2 2 2 0 Toll/interleukin-1 receptor domain Kinesin PF00225.23 CEG50415.1 - 1.9e-112 375.5 0.3 1.9e-112 375.5 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEG50415.1 - 2.5e-27 95.7 0.0 8.6e-27 93.9 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding ZZ PF00569.17 CEG50415.1 - 2.4e-09 36.9 2.7 2.4e-09 36.9 2.7 2.9 3 0 0 3 3 3 1 Zinc finger, ZZ type DUF4686 PF15742.5 CEG50415.1 - 0.057 12.5 17.6 0.39 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Mso1_Sec1_bdg PF14475.6 CEG50415.1 - 0.17 11.5 1.4 0.55 9.9 1.4 1.8 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Tup_N PF08581.10 CEG50415.1 - 0.73 10.2 6.6 2.4 8.5 0.2 2.9 2 0 0 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 CEG50415.1 - 0.91 9.9 19.8 0.046 14.1 1.2 4.6 4 1 1 5 5 5 0 Csm1 N-terminal domain Peptidase_M16 PF00675.20 CEG50416.1 - 3.7e-54 182.8 0.1 5.5e-54 182.2 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEG50416.1 - 4.7e-36 124.5 0.0 3.6e-35 121.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain CENP-F_C_Rb_bdg PF10490.9 CEG50419.1 - 0.011 15.2 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 CEG50420.1 - 2.2e-08 34.0 9.7 2.2e-08 34.0 9.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEG50420.1 - 2.7e-08 33.8 12.1 2.7e-08 33.8 12.1 1.6 2 0 0 2 2 2 1 Basic region leucine zipper SnoaL_2 PF12680.7 CEG50420.1 - 3.6e-05 24.3 0.0 6.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain bZIP_Maf PF03131.17 CEG50420.1 - 9.9e-05 22.8 5.9 9.9e-05 22.8 5.9 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor SnoaL PF07366.12 CEG50420.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SAS4 PF15460.6 CEG50420.1 - 0.012 15.7 3.5 0.023 14.8 3.5 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 TMCO5 PF14992.6 CEG50420.1 - 0.07 12.7 4.4 0.11 12.1 4.4 1.3 1 0 0 1 1 1 0 TMCO5 family MPM1 PF17234.2 CEG50420.1 - 4.7 7.4 6.2 16 5.7 6.2 1.8 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Pkinase_Tyr PF07714.17 CEG50421.1 - 9.8e-56 188.9 0.0 1.3e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEG50421.1 - 5.8e-54 183.2 0.0 8.4e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CEG50421.1 - 1.8e-05 23.7 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEG50421.1 - 0.0092 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family ACT_4 PF13291.6 CEG50421.1 - 0.033 14.8 0.2 0.076 13.6 0.2 1.6 1 0 0 1 1 1 0 ACT domain Ustilago_mating PF05722.12 CEG50421.1 - 0.06 12.9 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Haspin_kinase PF12330.8 CEG50421.1 - 0.098 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_trans_1_4 PF13692.6 CEG50424.1 - 9.7e-05 22.8 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CEG50424.1 - 0.0019 17.8 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PX PF00787.24 CEG50425.1 - 0.015 15.3 0.5 0.062 13.3 0.5 2.1 1 1 0 1 1 1 0 PX domain SKA2 PF16740.5 CEG50425.1 - 0.018 14.8 15.5 4.6 7.1 0.1 3.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF5137 PF17220.3 CEG50425.1 - 0.58 11.1 5.4 3.8 8.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF5137) FlaC_arch PF05377.11 CEG50425.1 - 3.2 8.2 11.4 1.4 9.4 0.3 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PH PF00169.29 CEG50426.1 - 6.1e-09 36.3 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CEG50426.1 - 0.071 13.4 0.1 0.29 11.4 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_C78 PF07910.13 CEG50427.1 - 2.1e-42 145.0 0.0 3.7e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CEG50427.1 - 7.1e-05 22.4 0.1 0.0035 16.8 0.0 2.8 3 0 0 3 3 3 1 Peptidase family C54 Vpu PF00558.19 CEG50428.1 - 0.03 14.1 2.7 0.16 11.8 0.3 2.2 2 0 0 2 2 2 0 Vpu protein CcmD PF04995.14 CEG50428.1 - 0.076 13.1 1.9 0.19 11.9 1.9 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Sulfatase PF00884.23 CEG50429.1 - 3e-30 105.7 0.1 7.2e-30 104.4 0.1 1.7 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CEG50429.1 - 0.00027 19.7 0.8 0.0024 16.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CEG50429.1 - 0.0037 16.9 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Uso1_p115_head PF04869.14 CEG50431.1 - 8.6e-19 67.8 2.9 6.9e-16 58.3 1.1 2.6 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.6 CEG50431.1 - 0.00061 20.1 1.0 0.034 14.5 0.1 4.0 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 CEG50431.1 - 0.0081 16.2 0.2 0.047 13.7 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEG50431.1 - 0.076 13.3 0.0 16 6.1 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat NPC1_N PF16414.5 CEG50432.1 - 4.1e-15 56.0 20.2 7.2e-15 55.2 20.2 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus ARL6IP6 PF15062.6 CEG50432.1 - 0.078 13.1 0.1 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Folate_rec PF03024.14 CEG50432.1 - 0.3 10.9 18.4 0.017 15.0 12.0 2.1 2 0 0 2 2 2 0 Folate receptor family Glycos_transf_1 PF00534.20 CEG50434.1 - 7e-05 22.4 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEG50434.1 - 0.00075 19.9 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RVT_2 PF07727.14 CEG50435.1 - 3.3e-19 69.5 0.1 4.3e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_membrane PF00664.23 CEG50437.1 - 3.8e-102 341.6 30.3 9.4e-57 192.7 5.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEG50437.1 - 7.7e-72 240.2 0.0 4.5e-35 121.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEG50437.1 - 2.2e-12 46.9 0.0 0.00021 20.8 1.5 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEG50437.1 - 4.8e-06 25.6 0.7 0.084 11.7 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CEG50437.1 - 6.2e-06 26.2 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEG50437.1 - 7.6e-06 25.6 0.7 0.079 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEG50437.1 - 8.5e-06 26.1 2.1 0.47 10.7 0.1 3.9 2 2 0 2 2 2 2 AAA domain APS_kinase PF01583.20 CEG50437.1 - 1.6e-05 24.9 0.0 0.014 15.2 0.0 2.8 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_16 PF13191.6 CEG50437.1 - 1.7e-05 25.2 0.1 0.21 11.9 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CEG50437.1 - 0.00019 21.6 3.2 0.71 10.2 0.4 4.3 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CEG50437.1 - 0.0015 18.3 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEG50437.1 - 0.0021 18.2 0.4 0.56 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEG50437.1 - 0.0036 17.1 0.2 12 5.6 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 CEG50437.1 - 0.0051 16.4 1.5 22 4.6 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 CEG50437.1 - 0.0082 16.6 6.1 1.5 9.3 0.1 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CEG50437.1 - 0.012 14.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DEAD PF00270.29 CEG50437.1 - 0.013 15.3 2.2 9.5 6.0 0.0 3.7 4 1 0 4 4 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 CEG50437.1 - 0.019 14.7 0.7 13 5.5 0.1 3.5 3 1 0 3 3 3 0 AAA domain PEPCK_ATP PF01293.20 CEG50437.1 - 0.03 13.0 0.0 0.74 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.6 CEG50437.1 - 0.036 14.6 0.0 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEG50437.1 - 0.059 13.6 0.0 2.8 8.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 CEG50437.1 - 0.1 13.1 1.1 9.1 6.7 0.1 2.8 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 CEG50437.1 - 0.12 12.4 0.8 10 6.1 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_21 PF13304.6 CEG50437.1 - 0.14 12.0 0.4 26 4.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CEG50437.1 - 0.15 12.2 0.2 20 5.3 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase CTP_transf_1 PF01148.20 CEG50439.1 - 2.9 7.6 40.0 2 8.1 31.3 2.8 2 1 0 2 2 2 0 Cytidylyltransferase family DUF5433 PF17498.2 CEG50439.1 - 4 7.7 9.1 0.58 10.4 1.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5433) Pex26 PF07163.12 CEG50440.1 - 0.0017 17.7 0.3 0.0028 17.0 0.3 1.4 1 0 0 1 1 1 1 Pex26 protein TTL PF03133.15 CEG50442.1 - 0.052 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family ORMDL PF04061.14 CEG50444.1 - 4.8e-35 120.3 0.1 5.7e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 ORMDL family Ripply PF14998.6 CEG50444.1 - 0.049 14.3 0.0 0.064 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription Regulator Ras PF00071.22 CEG50445.1 - 1.3e-57 194.0 0.0 1.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEG50445.1 - 2.6e-33 114.8 0.0 3.9e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEG50445.1 - 6.6e-14 51.7 0.0 7.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEG50445.1 - 0.013 15.5 0.0 0.019 15.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEG50445.1 - 0.052 13.5 0.0 9.9 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 CEG50445.1 - 0.071 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CEG50445.1 - 0.18 11.2 0.0 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Mago_nashi PF02792.14 CEG50446.1 - 4.9e-77 256.9 0.5 5.5e-77 256.7 0.5 1.0 1 0 0 1 1 1 1 Mago nashi protein DP PF08781.10 CEG50447.1 - 1.1e-31 109.6 4.6 1.7e-31 109.0 3.3 2.0 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.20 CEG50447.1 - 7.1e-24 83.6 0.4 7.1e-24 83.6 0.4 2.0 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Spo7 PF03907.13 CEG50447.1 - 0.054 13.0 0.8 0.12 11.8 0.8 1.5 1 1 0 1 1 1 0 Spo7-like protein Bromodomain PF00439.25 CEG50449.1 - 1.9e-19 69.5 0.2 5.2e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 CEG50449.1 - 5.7e-10 39.4 0.1 1e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEG50449.1 - 6.4e-08 32.6 0.1 1.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEG50449.1 - 7.1e-06 26.4 0.3 1.4e-05 25.4 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEG50449.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein RWP-RK PF02042.15 CEG50451.1 - 4.9e-19 68.0 2.3 6.9e-19 67.6 0.1 2.2 3 0 0 3 3 3 1 RWP-RK domain zf-DBF PF07535.12 CEG50451.1 - 0.26 11.4 1.3 0.71 10.0 0.2 2.1 2 0 0 2 2 2 0 DBF zinc finger Pribosyltran PF00156.27 CEG50452.1 - 1.2e-26 93.1 0.0 1.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEG50452.1 - 0.026 14.0 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CEG50452.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase BolA PF01722.18 CEG50453.1 - 9.8e-19 67.4 0.1 2.2e-18 66.3 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein RIC1 PF07064.13 CEG50454.1 - 8.8e-21 74.5 0.4 2.1e-20 73.2 0.4 1.7 1 0 0 1 1 1 1 RIC1 ACBP PF00887.19 CEG50454.1 - 4.4e-12 46.0 0.0 9.7e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein ANAPC4_WD40 PF12894.7 CEG50454.1 - 7.9e-06 26.1 0.0 0.0037 17.5 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PDZ PF00595.24 CEG50454.1 - 0.0029 17.9 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CEG50454.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain RWP-RK PF02042.15 CEG50455.1 - 4.6e-13 48.9 0.0 9.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_50 PF18024.1 CEG50455.1 - 0.0019 17.7 0.1 0.0046 16.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CEG50455.1 - 0.0038 16.9 0.1 0.022 14.4 0.1 2.3 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_6 PF01418.17 CEG50455.1 - 0.032 14.2 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family RWP-RK PF02042.15 CEG50456.1 - 2.3e-13 49.9 0.0 4.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 CEG50456.1 - 0.00044 19.9 0.2 0.0055 16.3 0.1 2.1 1 1 1 2 2 2 2 Sigma-70, region 4 TnsD PF15978.5 CEG50456.1 - 0.019 14.0 0.8 0.023 13.7 0.8 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_50 PF18024.1 CEG50456.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 CEG50456.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_38 PF13936.6 CEG50456.1 - 0.048 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 CEG50456.1 - 0.19 12.0 0.6 7.4 6.8 0.2 3.2 2 1 0 2 2 2 0 Helix-turn-helix domain Tim17 PF02466.19 CEG50457.1 - 0.00028 21.2 0.3 0.0012 19.2 0.1 2.2 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DnaJ PF00226.31 CEG50457.1 - 0.00037 20.6 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CEG50458.1 - 1.7e-76 257.1 0.0 2e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50458.1 - 2.2e-33 115.7 0.0 2.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEG50458.1 - 2.3e-06 27.1 0.1 0.00032 20.1 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CEG50458.1 - 0.0007 18.7 0.1 0.01 14.8 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEG50458.1 - 0.0031 16.9 0.1 0.0052 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEG50458.1 - 0.02 14.8 0.1 0.042 13.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEG50458.1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 CEG50458.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PRK PF00485.18 CEG50459.1 - 0.0023 17.7 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FTHFS PF01268.19 CEG50459.1 - 0.016 13.4 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Rhv PF00073.20 CEG50461.1 - 0.12 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 picornavirus capsid protein DUF2431 PF10354.9 CEG50462.1 - 2.3e-42 145.1 2.8 1e-41 143.0 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2431) zf-C3HC4_3 PF13920.6 CEG50462.1 - 2.7e-09 36.7 10.2 2.7e-09 36.7 10.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG50462.1 - 6.9e-09 35.4 10.1 2.5e-08 33.6 10.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEG50462.1 - 2.9e-07 30.2 8.3 7.6e-07 28.9 8.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEG50462.1 - 2.6e-06 27.2 12.2 2.6e-06 27.2 12.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG50462.1 - 7.9e-06 26.1 10.4 7.9e-06 26.1 10.4 2.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 CEG50462.1 - 1e-05 25.4 12.0 1e-05 25.4 12.0 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CEG50462.1 - 5.4e-05 23.0 2.8 0.00016 21.5 2.8 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEG50462.1 - 0.0003 21.0 6.7 0.0003 21.0 6.7 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEG50462.1 - 0.0019 18.2 9.4 0.0055 16.7 9.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger CENP-F_leu_zip PF10473.9 CEG50462.1 - 0.011 15.8 19.9 0.011 15.8 19.9 8.2 4 2 3 8 8 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_LEF-11 PF06385.12 CEG50462.1 - 0.08 13.4 2.8 0.21 12.1 1.2 2.8 2 0 0 2 2 1 0 Baculovirus LEF-11 protein zf-ANAPC11 PF12861.7 CEG50462.1 - 0.16 12.0 4.0 0.37 10.9 4.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger NapD PF03927.13 CEG50462.1 - 0.21 11.6 5.3 1.9 8.6 0.4 3.6 3 0 0 3 3 2 0 NapD protein zf-UDP PF14569.6 CEG50462.1 - 0.58 10.3 10.1 0.1 12.8 4.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 CEG50462.1 - 0.91 9.5 7.2 2.2 8.2 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CEG50462.1 - 2.8 7.8 14.3 0.18 11.6 8.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TauE PF01925.19 CEG50463.1 - 2.7e-18 66.5 19.1 1.7e-09 37.7 9.2 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE p53-inducible11 PF14936.6 CEG50463.1 - 0.72 9.9 5.6 0.11 12.5 1.3 1.8 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 ubiquitin PF00240.23 CEG50466.1 - 4.9e-07 29.4 0.0 9.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEG50466.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CEG50466.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CBS PF00571.28 CEG50467.1 - 2.3e-29 101.6 5.9 2.9e-07 30.8 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 CEG50467.1 - 8.6e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain GAF PF01590.26 CEG50467.1 - 0.0055 17.3 0.1 0.18 12.4 0.0 2.5 2 0 0 2 2 2 1 GAF domain WD40 PF00400.32 CEG50470.1 - 5.4e-26 90.3 15.8 5.2e-09 36.6 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEG50470.1 - 6.6e-14 52.0 0.0 2.9e-05 24.3 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEG50470.1 - 1.9e-06 27.1 0.2 0.044 12.8 0.0 3.7 3 2 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEG50470.1 - 0.0042 17.0 6.2 5.7 7.0 0.1 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CEG50470.1 - 0.018 14.9 0.0 1.6 8.6 0.0 3.5 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A p53-inducible11 PF14936.6 CEG50471.1 - 0.0018 18.4 2.1 0.0021 18.1 2.1 1.1 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 EamA PF00892.20 CEG50471.1 - 0.16 12.1 6.9 1.4 9.1 5.0 2.0 1 1 1 2 2 2 0 EamA-like transporter family EMP24_GP25L PF01105.24 CEG50472.1 - 4.6e-26 91.9 0.1 7.2e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAP2_C PF14360.6 CEG50472.1 - 1.9e-16 60.4 9.6 1.9e-16 60.4 9.6 3.5 3 1 0 3 3 3 1 PAP2 superfamily C-terminal Acetyltransf_3 PF13302.7 CEG50473.1 - 6.2e-12 46.4 0.0 9.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEG50473.1 - 3.5e-09 36.9 0.0 5.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CEG50473.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CHCH PF06747.13 CEG50474.1 - 3e-06 27.2 2.7 8.7e-06 25.7 2.7 1.8 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 CEG50474.1 - 0.0095 15.6 0.6 0.017 14.8 0.6 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 CEG50474.1 - 0.013 15.8 2.3 0.032 14.5 2.3 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CEG50474.1 - 0.026 14.5 1.9 0.056 13.5 1.9 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CEG50474.1 - 0.15 12.4 3.5 0.45 10.9 0.3 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) PspC PF04024.12 CEG50475.1 - 7 6.6 7.4 12 5.8 2.1 3.0 2 0 0 2 2 2 0 PspC domain RXLR PF16810.5 CEG50476.1 - 0.069 13.6 4.0 4.2 7.8 4.0 2.2 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Pkinase PF00069.25 CEG50478.1 - 4.8e-80 268.7 0.0 5.9e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEG50478.1 - 9.6e-36 123.4 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEG50478.1 - 1.3e-05 24.6 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEG50478.1 - 4.6e-05 22.9 0.0 0.0017 17.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CEG50478.1 - 0.0027 17.7 0.2 0.56 10.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEG50478.1 - 0.033 13.0 0.0 0.07 11.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CEG50478.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pre-PUA PF17832.1 CEG50479.1 - 6.3e-27 94.1 0.4 8.8e-27 93.6 0.4 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CEG50479.1 - 3.7e-16 58.8 0.0 5.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUSP PF06337.12 CEG50480.1 - 8.4e-08 32.7 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 DUSP domain Luteo_PO PF04662.13 CEG50482.1 - 0.066 12.9 0.0 0.069 12.8 0.0 1.0 1 0 0 1 1 1 0 Luteovirus P0 protein RAWUL PF16207.5 CEG50484.1 - 2.4e-08 34.5 0.8 6.2e-08 33.2 0.8 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 CEG50484.1 - 3.6e-07 29.9 6.4 8.8e-07 28.7 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEG50484.1 - 4.7e-06 26.4 6.8 5.3e-06 26.2 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEG50484.1 - 5.2e-06 26.4 2.3 6.8e-05 22.8 3.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger DUF3337 PF11816.8 CEG50484.1 - 6.6e-06 26.1 0.1 1.4e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) zf-Nse PF11789.8 CEG50484.1 - 0.0014 18.4 2.9 0.0037 17.0 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CEG50484.1 - 0.0015 18.7 3.5 0.004 17.3 3.5 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CEG50484.1 - 0.0017 18.5 9.7 0.0041 17.2 9.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEG50484.1 - 0.0029 17.4 3.6 0.0068 16.2 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEG50484.1 - 0.0044 17.3 5.6 0.01 16.2 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEG50484.1 - 0.0085 16.0 7.4 0.018 15.0 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 CEG50484.1 - 0.3 11.0 3.0 0.55 10.1 3.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein NIF PF03031.18 CEG50485.1 - 1.8e-52 177.3 0.2 2.5e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CEG50485.1 - 0.16 12.4 0.1 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 CEG50486.1 - 1.4e-53 180.8 0.2 2.1e-53 180.3 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CEG50486.1 - 0.09 13.2 0.1 0.78 10.1 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PH PF00169.29 CEG50488.1 - 1e-17 64.5 0.3 7.6e-08 32.8 0.1 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CEG50488.1 - 5.8e-06 26.7 2.8 0.0025 18.2 0.0 3.9 4 0 0 4 4 4 2 Pleckstrin homology domain Chalcone PF02431.15 CEG50488.1 - 0.0035 16.8 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Chalcone-flavanone isomerase LCM PF04072.14 CEG50489.1 - 7.4e-22 78.2 0.0 2.1e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_1 PF00583.25 CEG50489.1 - 1.2e-14 54.5 0.1 3.9e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEG50489.1 - 4.2e-11 43.1 0.0 9.8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEG50489.1 - 2.4e-07 30.7 0.0 6.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEG50489.1 - 0.013 15.6 0.0 0.076 13.1 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEG50489.1 - 0.093 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 CEG50490.1 - 1.3e-19 69.7 5.3 2.6e-10 39.9 1.3 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CEG50490.1 - 4.6e-17 61.8 2.2 3.6e-05 24.0 0.1 4.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEG50490.1 - 1.4e-05 24.7 2.1 0.054 13.0 0.1 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CEG50490.1 - 4e-05 23.3 7.3 2 8.7 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CEG50490.1 - 5e-05 23.3 7.9 2.3 9.1 0.1 5.3 5 2 0 5 5 5 2 Leucine Rich Repeat EF-hand_7 PF13499.6 CEG50491.1 - 4.4e-06 27.0 0.0 5.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEG50491.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEG50491.1 - 0.14 11.8 0.0 0.65 9.7 0.0 2.2 3 0 0 3 3 3 0 EF hand NIF PF03031.18 CEG50492.1 - 5.9e-53 178.8 1.6 8.6e-53 178.3 0.6 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 CEG50492.1 - 0.15 12.5 0.0 1.5 9.2 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lebercilin PF15619.6 CEG50494.1 - 0.063 12.9 15.0 0.25 11.0 7.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 CEG50494.1 - 0.14 11.9 9.7 0.038 13.7 4.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mis14 PF08641.12 CEG50494.1 - 0.24 11.7 12.8 0.3 11.4 11.4 1.9 1 1 0 1 1 1 0 Kinetochore protein Mis14 like DUF1664 PF07889.12 CEG50494.1 - 0.27 11.3 5.4 6.6 6.8 0.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 CEG50494.1 - 0.38 11.2 10.0 0.62 10.5 10.0 1.4 1 0 0 1 1 1 0 Fez1 ALMT PF11744.8 CEG50494.1 - 0.57 9.0 9.7 0.73 8.6 9.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc7 PF08317.11 CEG50494.1 - 0.59 9.0 14.6 0.22 10.4 11.0 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein SLATT_1 PF18181.1 CEG50494.1 - 0.7 9.8 4.8 2.1 8.3 1.1 2.3 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_C98 PF15499.6 CEG50494.1 - 0.86 9.0 4.1 0.45 10.0 0.6 1.9 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PKcGMP_CC PF16808.5 CEG50494.1 - 1.1 9.2 6.1 0.34 10.8 1.9 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 CEG50494.1 - 5.6 7.7 9.6 3.2 8.4 3.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CSN5_C PF18323.1 CEG50494.1 - 8 7.5 8.8 3.6 8.6 3.4 2.5 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Ribonuc_2-5A PF06479.12 CEG50495.1 - 0.17 12.0 0.2 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 Ribonuclease 2-5A Aldedh PF00171.22 CEG50496.1 - 1.4e-67 228.2 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PX PF00787.24 CEG50497.1 - 2.3e-05 24.4 2.7 5.3e-05 23.2 2.7 1.8 1 1 0 1 1 1 1 PX domain TFCD_C PF12612.8 CEG50500.1 - 7.2e-49 166.2 0.4 5.7e-48 163.3 0.1 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal adh_short PF00106.25 CEG50500.1 - 2.6e-20 72.7 0.2 5.2e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG50500.1 - 6.2e-14 52.1 0.4 1.3e-13 51.0 0.4 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEG50500.1 - 5.1e-09 36.3 0.1 2.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 KR domain HEAT_2 PF13646.6 CEG50500.1 - 5.3e-08 33.1 4.1 0.37 11.2 0.4 6.1 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 CEG50500.1 - 1.5e-07 31.1 12.7 0.21 11.9 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat Pyr_redox_3 PF13738.6 CEG50500.1 - 0.00087 18.6 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HEAT_EZ PF13513.6 CEG50500.1 - 0.0055 17.2 18.1 2.1 8.9 0.0 8.0 7 2 1 8 8 8 1 HEAT-like repeat HEAT_PBS PF03130.16 CEG50500.1 - 0.007 16.9 0.3 39 5.3 0.0 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Rif1_N PF12231.8 CEG50500.1 - 0.01 14.9 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal 3HCDH_N PF02737.18 CEG50500.1 - 0.075 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CEG50500.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CEG50501.1 - 2.6e-11 43.3 0.4 3e-11 43.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEG50501.1 - 2.9e-06 27.0 0.2 3.7e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.6 CEG50501.1 - 4.1e-05 23.0 0.0 4.5e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 CEG50501.1 - 0.00029 20.8 0.1 0.0004 20.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Toprim_4 PF13662.6 CEG50501.1 - 0.017 15.6 0.0 0.93 10.0 0.0 2.0 1 1 1 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.19 CEG50501.1 - 0.041 13.2 0.0 0.045 13.1 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CEG50501.1 - 0.056 13.7 0.1 0.082 13.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEG50501.1 - 0.062 13.4 0.1 0.069 13.2 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 CEG50501.1 - 0.088 12.7 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 CEG50501.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_lid_6 PF17866.1 CEG50502.1 - 0.0055 16.9 0.1 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA lid domain Cna_B PF05738.13 CEG50502.1 - 0.11 13.1 0.3 0.21 12.1 0.3 1.6 1 1 0 1 1 1 0 Cna protein B-type domain ubiquitin PF00240.23 CEG50503.1 - 0.007 16.1 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_4 PF18036.1 CEG50503.1 - 0.036 14.1 0.0 0.25 11.4 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain Glyoxalase_4 PF13669.6 CEG50503.1 - 0.044 14.1 0.0 0.079 13.2 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DWNN PF08783.11 CEG50503.1 - 0.091 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 DWNN domain MFS_1 PF07690.16 CEG50505.1 - 1.2e-19 70.4 24.0 5.5e-12 45.3 5.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 CEG50505.1 - 0.011 15.1 0.7 0.018 14.4 0.0 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SieB PF14163.6 CEG50505.1 - 0.23 11.0 1.4 0.95 9.0 0.0 2.4 2 1 0 2 2 2 0 Super-infection exclusion protein B COG4 PF08318.12 CEG50506.1 - 4.2e-17 62.2 8.2 2e-16 60.0 3.9 3.1 2 1 0 2 2 2 1 COG4 transport protein HtrL_YibB PF09612.10 CEG50506.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) GP3_package PF16677.5 CEG50506.1 - 0.02 15.0 0.1 2.2 8.4 0.0 3.3 2 1 1 3 3 3 0 DNA-packaging protein gp3 DUF1643 PF07799.12 CEG50506.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) ADK PF00406.22 CEG50507.1 - 4e-39 134.1 0.7 3.7e-37 127.7 0.7 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEG50507.1 - 7.4e-27 94.4 1.2 1e-24 87.5 1.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEG50507.1 - 0.0012 19.4 0.0 0.0018 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CEG50507.1 - 0.0035 17.0 0.4 0.02 14.5 0.1 1.9 2 0 0 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 CEG50507.1 - 0.0059 16.8 0.0 0.0088 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEG50507.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 CEG50507.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 CEG50507.1 - 0.13 12.6 0.2 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEG50507.1 - 0.24 11.7 0.7 1.5 9.1 0.5 2.3 1 1 0 1 1 1 0 AAA domain V-ATPase_H_N PF03224.14 CEG50508.1 - 8.6e-42 143.5 0.0 1.1e-40 139.9 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CEG50508.1 - 8.4e-39 132.3 2.0 1.5e-37 128.2 0.4 2.6 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 CEG50508.1 - 1.2e-10 41.0 5.2 0.3 11.2 0.1 5.3 4 1 1 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CEG50508.1 - 0.0021 18.2 5.1 0.37 11.2 0.0 4.7 4 1 1 5 5 5 1 HEAT repeat DRIM PF07539.12 CEG50508.1 - 0.0068 14.8 0.1 0.018 13.4 0.0 1.6 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.6 CEG50508.1 - 0.011 16.1 3.6 1.6 9.2 0.0 4.4 2 2 3 5 5 5 0 HEAT repeats Arm_2 PF04826.13 CEG50508.1 - 0.025 14.1 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Armadillo-like HEAT_EZ PF13513.6 CEG50508.1 - 0.044 14.3 3.1 6.8 7.3 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat PEX11 PF05648.14 CEG50509.1 - 1.3e-13 51.0 0.1 1.6e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PH PF00169.29 CEG50510.1 - 0.0025 18.3 0.0 0.0041 17.6 0.0 1.3 1 0 0 1 1 1 1 PH domain MU2_FHA PF18221.1 CEG50510.1 - 0.05 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain malic PF00390.19 CEG50511.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Zwilch PF09817.9 CEG50513.1 - 0.042 12.3 0.0 0.047 12.1 0.0 1.0 1 0 0 1 1 1 0 RZZ complex, subunit zwilch RRM_1 PF00076.22 CEG50517.1 - 9.2e-34 115.1 0.2 8e-16 57.6 0.4 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEG50517.1 - 2e-11 43.9 0.3 2.5e-06 27.5 0.3 2.6 2 0 0 2 2 2 2 RNA recognition motif SBF2 PF12335.8 CEG50518.1 - 2.1e-05 24.3 0.2 0.049 13.2 0.1 2.6 2 0 0 2 2 2 2 Myotubularin protein FCH PF00611.23 CEG50518.1 - 0.0067 16.7 0.2 0.16 12.3 0.1 3.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain zf-4CXXC_R1 PF10497.9 CEG50518.1 - 0.13 12.5 2.0 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Thiolase_N PF00108.23 CEG50519.1 - 3.3e-86 288.9 0.0 4.5e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEG50519.1 - 6e-46 155.1 1.1 1.4e-45 153.9 1.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEG50519.1 - 1.3e-05 24.9 1.0 0.00052 19.7 0.5 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEG50519.1 - 0.00042 20.1 1.6 0.31 10.9 0.0 3.3 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pex2_Pex12 PF04757.14 CEG50520.1 - 3e-31 108.7 9.4 4e-31 108.4 9.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 CEG50520.1 - 1.2e-05 25.1 2.4 2.6e-05 23.9 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEG50520.1 - 0.00018 21.3 4.1 0.00018 21.3 4.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEG50520.1 - 0.0028 17.5 2.4 0.0081 16.0 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CEG50520.1 - 0.018 14.6 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_2 PF13639.6 CEG50520.1 - 0.047 14.0 5.3 0.29 11.5 5.5 2.1 1 1 1 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 CEG50520.1 - 0.12 12.3 3.8 0.64 9.9 4.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEG50520.1 - 0.17 12.2 2.6 0.64 10.3 2.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Remorin_N PF03766.13 CEG50520.1 - 0.19 11.8 0.4 0.39 10.8 0.4 1.5 1 0 0 1 1 1 0 Remorin, N-terminal region zf-RING_UBOX PF13445.6 CEG50520.1 - 0.29 11.2 7.0 0.73 9.9 7.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CEG50520.1 - 0.37 11.0 6.7 0.89 9.8 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PRIMA1 PF16101.5 CEG50520.1 - 0.6 10.2 3.9 0.47 10.5 2.1 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 zf-RING_5 PF14634.6 CEG50520.1 - 1.2 9.2 5.1 8 6.5 5.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Spermine_synth PF01564.17 CEG50521.1 - 0.045 13.2 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Dus PF01207.17 CEG50522.1 - 2.3e-80 270.0 0.0 2.9e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CEG50522.1 - 2.3e-06 27.2 0.0 4.5e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 CEG50522.1 - 2e-05 23.9 0.0 0.00084 18.6 0.0 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CEG50522.1 - 6.5e-05 22.4 0.0 0.0004 19.8 0.0 2.1 2 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 CEG50522.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase SOR_SNZ PF01680.17 CEG50522.1 - 0.0025 17.7 0.1 0.025 14.4 0.0 2.2 1 1 1 2 2 2 1 SOR/SNZ family G3P_antiterm PF04309.12 CEG50522.1 - 0.0029 17.1 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 CEG50522.1 - 0.0033 16.9 0.0 0.0081 15.6 0.0 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 CEG50522.1 - 0.012 14.7 0.0 0.052 12.6 0.0 1.8 1 1 1 2 2 2 0 FMN-dependent dehydrogenase IMPDH PF00478.25 CEG50522.1 - 0.016 14.3 0.0 0.044 12.8 0.0 1.6 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 CEG50522.1 - 0.11 11.3 0.0 4.8 5.9 0.0 2.4 1 1 1 2 2 2 0 Tryptophan synthase alpha chain SET PF00856.28 CEG50523.1 - 1.8e-17 64.2 0.3 1.6e-16 61.1 0.1 2.8 2 1 0 2 2 2 1 SET domain Pkinase PF00069.25 CEG50523.1 - 2.1e-17 63.4 0.0 4.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AWS PF17907.1 CEG50523.1 - 2.4e-07 30.7 3.6 7.5e-07 29.1 3.6 1.8 1 0 0 1 1 1 1 AWS domain RRM_1 PF00076.22 CEG50523.1 - 0.044 13.6 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 CEG50523.1 - 0.08 12.7 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 Cyclin, N-terminal domain Corona_5a PF06336.11 CEG50523.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Coronavirus 5a protein Glyco_hydro_72 PF03198.14 CEG50524.1 - 7.5e-50 170.0 0.3 1e-49 169.6 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase GH115_C PF17829.1 CEG50524.1 - 0.089 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain NmrA PF05368.13 CEG50526.1 - 4.8e-32 111.4 0.8 6.2e-32 111.0 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CEG50526.1 - 7e-12 45.6 0.8 1.9e-11 44.2 0.8 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CEG50526.1 - 3e-08 34.0 0.2 6.5e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEG50526.1 - 6.2e-06 26.3 0.2 1.8e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 CEG50526.1 - 4.9e-05 22.5 0.7 8.1e-05 21.7 0.1 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 CEG50526.1 - 0.0019 18.7 0.5 0.0051 17.4 0.5 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CEG50526.1 - 0.002 17.8 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 CEG50526.1 - 0.0032 17.9 1.1 0.0069 16.8 0.1 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding KR PF08659.10 CEG50526.1 - 0.0036 17.2 0.2 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 CEG50526.1 - 0.0046 17.2 0.2 0.0091 16.2 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain PglD_N PF17836.1 CEG50526.1 - 0.0058 17.3 0.1 0.03 14.9 0.1 2.2 2 0 0 2 2 2 1 PglD N-terminal domain AlaDh_PNT_C PF01262.21 CEG50526.1 - 0.012 14.9 0.9 0.024 13.9 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_deac_1 PF01522.21 CEG50526.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase NAD_binding_2 PF03446.15 CEG50526.1 - 0.013 15.7 0.1 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 CEG50526.1 - 0.026 14.1 0.1 0.063 12.9 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GFO_IDH_MocA PF01408.22 CEG50526.1 - 0.045 14.6 0.1 0.077 13.8 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 CEG50526.1 - 0.12 12.8 0.2 0.25 11.8 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CEG50526.1 - 0.16 11.2 0.0 0.36 10.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L16 PF00252.18 CEI80203.1 - 9.1e-21 74.2 0.1 1e-20 74.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Biotin_lipoyl_2 PF13533.6 CEI80203.1 - 0.023 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Biotin-lipoyl like Proton_antipo_M PF00361.20 CEI80204.1 - 6.5e-12 45.3 0.4 1.1e-11 44.5 0.2 1.5 1 1 1 2 2 2 1 Proton-conducting membrane transporter Complex1_49kDa PF00346.19 CEI80205.1 - 2.2e-16 59.7 0.3 9.2e-16 57.7 0.1 1.8 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ATP-synt_ab PF00006.25 CEI80206.1 - 2.7e-72 242.9 0.0 4e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CEI80206.1 - 2.9e-24 85.8 3.6 5.3e-24 85.0 3.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CEI80206.1 - 1.8e-13 50.8 0.5 1.8e-13 50.8 0.5 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CEI80206.1 - 0.00027 21.0 0.2 0.001 19.2 0.2 2.0 1 1 1 2 2 2 1 HAS barrel domain COX2 PF00116.20 CEI80207.1 - 3.4e-61 204.4 0.1 4e-61 204.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Plasmopara_halstedii-GCA_900000015.1/GCA_900000015.1_Plasmopara_halstedii_genome_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Plasmopara_halstedii-GCA_900000015.1/GCA_900000015.1_Plasmopara_halstedii_genome_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Plasmopara_halstedii-GCA_900000015.1/GCA_900000015.1_Plasmopara_halstedii_genome_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Plasmopara_halstedii-GCA_900000015.1/GCA_900000015.1_Plasmopara_halstedii_genome_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 11:11:23 2019 # [ok]